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The article presents a selection of studies presented at the 48th Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, Illinois, which focused on issues relating to pharmacovigilance and adverse drug reactions associated with cancer therapies. A U.S.-based phase III trial showed the efficacy of duloxetine for the treatment of chemotherapy-induced peripheral neuropathy. A study revealed the link between the use of thiazolidinediones and bladder cancer.

An abstract of the article "Adverse Event Following Immunization (AEFI) Surveillance in India: Position Paper of Indian Academy of Pediatrics 2013," by A. J. Chitkara and colleagues is presented.

B Author Information b An event is serious (based on the ICH definition) when the patient outcome is: * death * life-threatening * hospitalisation * disability * congenital anomaly * other medically important event A 20-year-old man developed drug reaction with eosinophilia and systemic symptoms (DRESS) following treatment with ranitidine and rifampicin. The man developed reactivation of DRESS following patch test (PT) with ranitidine. Nine months later, initial skin testing showed positive patch test (PT) and intradermal test (IDT) for ranitidine. [Extracted from the article]

B » Editorial comment: b Details of this case report have previously been published [see Reactions 1717 p26; 803342730]. In the current paper, the author organisation and country is updated. Characterisation of an acute localised pustular drug reaction. [Extracted from the article]

The article presents a comment to a paper entitled "Sustained Erythroid Response in a Patient with Myelofibrosis Receiving Concomitant Treatment with Ruxolitinib and Deferasirox."

The article presents the paper entitled "Severe anaphylaxis after pelvic examination: A case report of dual latex and chlorhexidine allergies."

The article presents information on the research paper entitled "Delayed hypersensitivity to ribavirin confirmed by provocation test," published in the "Journal of Investigational Allergology and Clinical Immunology."

The article discusses the highlights of studies on side effects of antiepileptic drugs (AEDs) presented at the 2009 meeting of the American Epilepsy Society (AES) in the U.S. A presentation during the meeting criticized an analysis which showed the risks of suicidal ideation and suicidal behavior for not including all antiepileptic drugs. Another paper showed that changes in the treatment using AES had no effects on suicidality.