1. Atopic Dermatitis.
- Author
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Ständer, Sonja
- Subjects
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ATOPIC dermatitis , *ECZEMA , *MOLLUSCUM contagiosum , *ALLERGIC conjunctivitis , *PLASMA cell diseases , *COVID-19 , *ATOPIC dermatitis treatment , *SKIN , *PHOTOTHERAPY , *IMMUNOSUPPRESSIVE agents , *ALLERGIES , *DISEASE complications - Abstract
The article focuses on oral Janus kinase 1 GAK1) inhibitor abrocitinib, which reduces interleukin-4 and interleukin-13 signaling, is being investigated for the treatment of atopic dermatitis and the data from trials comparing JAK1 inhibitors with monoclonal antibodies, such as dupilumab, that block interleukin-4 receptors are limited. Topics include the abrocitinib dose differed significantly from dupilumab with respect to most other key secondary end-point comparisons at week 16.
- Published
- 2021
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