1. The interactome of human EGF/ErbB receptors.
- Author
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Uetz, Peter and Stagljar, Igor
- Subjects
- *
PROTEOMICS , *PROTEIN microarrays , *HER2 protein , *PROTEINS , *CYTOSOL - Abstract
The article features comments on EGFR signaling. By using protein microarray and quantitative proteomics technologies, a group has recently identified proteins associated with the cytosolic domains of the human EGFR family. In a related project, others have used protein microarrays to identify ErbB interactors. It is commented that the dramatic differences are due to the fact that the two groups looked at very different things. The paper indicates that systems biology is in its nascent stage.
- Published
- 2006
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