1. Maternal Serum and Umbilical Cord Brain Natriuretic Peptide Levels in Fetuses with Intrauterine Growth Restriction.
- Author
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Eroğlu, Hasan, Erdöl, Mehmet Akif, Tonyalı, Nazan Vanlı, Örgül, Gökçen, Biriken, Derya, Yücel, Aykan, Yazihan, Nuray, and Şahin, Dilek
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FETAL growth retardation , *FETAL development , *UMBILICAL cord , *CORD blood , *PREGNANT women , *BRAIN natriuretic factor , *PLACENTAL growth factor - Abstract
Aim: We compared maternal serum and fetal cord blood proBNP levels in healthy pregnancies to those with intrauterine growth restriction (IUGR). Methods: Prospectively, maternal and cord blood samples at childbirth of 40 pregnant women with isolated IUGR and 40 healthy pregnant women were evaluated for ProBNP levels. Results: The mean serum ProBNP level was significantly higher in newborn cord blood with IUGR than in the control group (181.28 ± 145.37 vs. 91.41 ± 49.77 pg/mL, p = <0.01). Mean serum ProBNP level trended higher in women with IUGR compared to the controls, but was not statistically significant (124.21 ± 113.32 vs. 88.73 ± 85.18 pg/mL, p= >0.05). Conclusion: Third trimester mean proBNP in fetal cord blood are increased in IUGR fetuses at term birth compared to pregnancies with normal fetal growth. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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