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• An intrinsically stretchable tribotronic mechanoplastic artificial synapse was proposed. • The device can be modulated by the triboelectric potential induced by mechanical stimulation. • The device establishes an active mechanically adjustable synaptic plasticity. Stretchable synaptic devices with adaptability to elastic deformation, sensing environmental stimuli, and unique information processing functions are of great significance for the development of the next generation of artificial nervous systems. Here, an intrinsically stretchable tribotronic mechanoplastic artificial synapse (STMAS) is proposed, which is integrated by a triboelectric nanogenerator and an electrolyte-gated transistor with ion-gel as dielectric layer. The STMAS can be modulated by the triboelectric potential induced by mechanical stimulation without the need to apply an external gate voltage, achieving an active mechanical tuning of synaptic plasticity such as excitatory postsynaptic current, paired-pulse facilitation, short-term plasticity, and long-term plasticity. The STMAS exhibits stable synaptic plasticity under 0–50% stretcher strain in parallel and vertical to channel directions, respectively. Furthermore, the International Morse code triggered by mechanical signals has been successfully mimicked. This work has achieved an intrinsically stretchable tribotronic artificial synapse with mechanically tuned synaptic behavior, which will help promote the development of artificial nervous systems and expand the applications of artificial synapses in intelligent robotics, artificial limbs and human–machine interaction. [ABSTRACT FROM AUTHOR]

[Display omitted] • P. chrysosporium could tolerate IMI and transform 93.5% for 6 days. • Manganese and lignin peroxidase played important roles in IMI transformation. • IMI mainly underwent nitrate-reduction, hydroxylation, and de-chlorination process. • MD results explained the reactive sites and metabolic mechanisms of enzymes. • 6-chloronicotinic acid, a less neurologically toxic major metabolite, was detected. As one of the widely used neonicotinoid insecticide, imidacloprid (IMI) poses serious threat on many kinds of non-target species. The acceleration of its removal from the contaminated environment is therefore an urgent task. Herein, the transformation of IMI by white-rot fungus Phanerochaete chrysosporium was examined, and the reaction mechanism underlying enzymes-mediated IMI biotransformation was elucidated. In addition, transformed products, pathways, and toxicity to Escherichia coli and Microcystis aeruginosa or the growth of rice seeds were investigated. P. chrysosporium could efficiently transform 93.5% of IMI for 6 days primarily through biotransformation, in which extracellular manganese peroxidase and lignin peroxidase substantially responded to transform IMI. IMI mainly underwent nitrate reduction, hydroxylation, and de-chlorination. A less neurologically toxic major metabolite of IMI, 6-chloronicotinic acid, was detected. Molecular dynamics simulation demonstrated that IMI stably bonded to active pocket of extracellular enzymes. This study reveals the key metabolic mechanism and fate of IMI in environment, and highlights the potential of fungi for IMI transformation. [ABSTRACT FROM AUTHOR]