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This volume deals with the various fabrication techniques, surface functionalization and biomedical applications of polymeric fibers possessing different scale and structure. It provides an overview of fabrication techniques such as Co-axial, Centrifugal, Melt and Yarning to procure multiscale, tubular and layered fibrous scaffold employed for biomedical applications. The chapters in this volume discusse the surface/chemical functionalization of fibers which enhance the biological properties of the fibrous scaffolds as well as the development of hybrid, layered and external stimuli-responsive fibrous scaffolds that hold potential application in biosensor and other biomedical fields. In addition, recent advances and applications of polymeric multiscale fibers in tissue engineering, regenerative medicine and drug delivery are presented. The potential use of fibrous scaffolds in bone, neural, tendon/ligament and cardiac tissue engineering, nanofibers as an antimicrobial wound dressing, employed in cancer theragnostics and in the treatment of skin/periodontal infections are discussed. The volume provides expert knowledge on the fabrication techniques, development of different scale and hybrid structure fibers, surface functionalization, layered and external stimuli responsive fibrous scaffolds. It will be beneficial to material/biomaterials scientists, bioengineering and biotechnologists by providing a better understanding on the subject of the innovative applications of fibrous scaffolds in drug delivery, tissue engineering, wound dressings and regenerative medicine.

This edited collection deals with the structure-property relationships and biomedical applications of carboxymethyl chitosan derivatives in different fields. Readers will detailed overview of the preparatory methods involved in the derivatives of carboxymethyl chitosan and its interaction with metal ions. The chapters provide a detailed overview of the different types of carboxymethyl chitosan derivatives, including the preparatory methods involved, the interactions with metal ions, and the antimicrobial activities. These different forms of carboxymethyl chitosan derivatives are found to be potentially used in food packaging, in enhancing saltiness, as biosensors, and also as wound dressing. Chapters are also devoted to the fabrication and biomedical applications of carboxymethyl chitosan derivatives-based nanofibers as well as the interaction of carboxymethyl chitosan with blood in blood clotting and the underlying mechanism. Contributing authors additionally explore topicsrelated to carboxymethyl chitosan-based hydrogels, films, scaffolds, fibers, and composites. Finally, this volume presents the current challenges in developing biomedical products based on carboxymethyl chitosan derivatives. This book will be of interest not only to chemists, but to all scientists working in the fields of material/environmental science, biological science, and biomaterials. These chapters are great resources for any researcher who works with structure-property relationships, biological interactions, and the applications of carboxymethyl chitosan derivatives in different biomedical fields.

Polymeric Nanoparticles of Chitosan Derivatives as DNA and siRNA Carriers, by Y. K. Kim, H. L. Jiang, Y. J. Choi, I. K. Park, M. H. Cho and C. S. Cho.- Chitosan and Its Derivatives for Drug Delivery Perspective, by T. A. Sonia and C. P. Sharma.- Chitosan-based Nanoparticles in Cancer Therapy, by V.-K. Lakshmanan, K. S. Snima, J. D. Bumgardner, S. V. Nair, and R. Jayakumar.- Chitosan and Thiolated Chitosan, by F. Sarti and A. Bernkop-Schnürch.- Chitosan-Based Particulate Systems for Non-Invasive Vaccine Delivery, by S. Şenel.- Multifunctional Chitosan Nanoparticles for Tumor Imaging and Therapy, by J. Y. Yhee, Heebeom Koo, Dong Eun Lee, Kuiwon Choi, Ick Chan Kwon and Kwangmeyung Kim.- Chitosan-Coated Iron Oxide Nanoparticles for Molecular Imaging and Drug Delivery, by H. Arami, Z. Stephen, O. Veiseh and M. Zhang.- Chitosan: Its Applications in Drug-Eluting Devices, by Mei -Chin Chen, Fwu -Long Mi, Zi -Xian Liao and Hsing -Wen Sung.-