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Milestones in Immunology: Based on Collected Papers contains scientific milestones relating to the history of medicine over the past two centuries. The book highlights the contributions of pioneering scientists whose discoveries have paved the way for researchers working in the field of immunology. As the science of immunology grew from knowledge that survivors of common infectious diseases rarely contracted them again, the book uses this as a central thesis, helping readers understand how the adaptive immune system aids in defense against pathogens. In addition, the book covers special fields, such as immunohistochemistry, immunogenetics and immunopathology. For the past century, immunology has fascinated and inspired some of the greatest scientists of our time. Numerous Nobel Prizes have been awarded for fundamental discoveries in immunology, from Paul Ehrlich'work on antibodies (1908) to the studies of Zinkernagel and Doherty (1986) elucidating mechanisms of cell-mediated immunity. - Provides on update on developments since the publication of Nobel prize winning research for fundamental discoveries in immunology - Discusses the changing theories and technologies that guided the field - Lists all the important discoveries and books in the field - Explains, in detail, the many Nobel prize-winning contributions of immunologists - Provides recognition of the scientists who were pioneers of landmark discoveries in immunology

Xylanolytic Enzymes describes the enzyme structure and its interaction with plant cell walls, the properties and production of different enzymes and their application, and the knowledge gathered on the hydrolysis mechanism of hemicellulose. The knowledge gathered about the hydrolysis mechanism of the hemicelluloses, especially xylans, has greatly promoted the rapid application of these enzymes in new areas. Recently there has been much industrial interest in xylan and its hydrolytic enzymatic complex, as a supplement and for the manufacturing of food, drinks, textiles, pulps and paper, and ethanol; and in xylitol production as a fermentation substrate for the production of enzymes. This book describes xylan as a major component of plant hemicelluloses. - Presents a thorough overview of all aspects of xylanolytic enzymes - Gives up-to-date authoritative information and cites pertinent research - Includes studies on xylanase regulation and synergistic action between multiple forms of xylanase

For many biologists, statistics are an anathema; but statistical analysis of quantitative and qualitative data is of considerable importance. Although spreadsheet software provides a diverse range of statistical tools, users are usually unsure which technique should be used. This book provides the basic statistical theory and practice to understand the types of tests frequently needed for the assessment of microbiological data. No prior knowledge of statistical techniques is required. Even when data can be given to a professional statistician for analysis, the microbiologist needs to have at least a general understanding of the underlying basis of statistical procedures in order to communicate effectively with the statistician. The book contains many worked examples to illustrate the use of the techniques and provides a plethora of references both to standard statistical works and to relevant original scientific papers on food microbiology. - Basil Jarvis has had many years of experience in academic, research and industrial food microbiology and is a Past President of the Society for Applied Microbiology. He has published several edited books and more than 200 scientific articles concerned with food microbiology - NEW to this edition - chapters on Measurement Uncertainty in Microbiology, Statistical Process Control, Food Safety Objectives, Risk Assessment and Microbiological Criteria and a chapter on Validation of Microbiological Methods by Dr Sharon Brunelle, AOAC consultant - Includes additional figures and tables together with many worked examples to illustrate the use of specific procedures in the analysis of data obtained in the microbiological examination of foods

Genetics and Biotechnology of Bacilli, Volume 2 is a collection of papers from the'Fourth International Conference on Bacilli'held in California on June 21-24, 1987. One paper reviews the results of cloning and characterization of genes for secreted enzyme and of genes that control the expression of secreted enzymes in relation with other prokaryotic regulatory systems. Other papers tackle the regulation of gene expression during sporulation, the sigma factors, bacterial toxins, and antibiotic resistance genes. One paper reports that three genes responsible for the code for peptides found in BT cuboidal crystals have been successfully cloned. The three codes have different toxic characteristics in relation to tobacco hornworm larvae or mosquito larvae. Other papers examine replication. Such examination pertains to the two levels of control on the chromosome involved in DNA replication, or to the possible functional importance that several membranes associated DNA subcomplexes can have in Bacillus subtilis, where one of these appear to control initiation. Other papers discus secretion and extracellular enzymes, as well as, the different genetic systems and methods. This collection can prove beneficial for biochemists, micro-biologists, cellular researchers, and academicians involved in the study of cellular biology, microchemistry, or toxicology.

Fungal Biotechnology: Industrial Applications and Market Potential provides a comprehensive and holistic review on the uses of filamentous fungi in food, agriculture, and pharmaceutical industries. In addition to genetic and metabolic engineering approaches for heterologous proteins production in fungi, the book focuses on fungi as a source of bioactive compounds like enzymes, polysaccharides, alkaloids, glycoproteins, and phytohormones. It describes recent trends in the use of fungi for solid waste management and its subsequent conversion into value added products. As a complete guide on the broad uses of microfungi in different industrial sectors while maintaining a sustainable environment, this book is a beneficial resource for students, researchers, and scientists as an effective means of imparting knowledge on the current trends and future perspectives in the field of fungal biotechnology. - Emphasizes updated research and developments in the field of Fungal Biotechnology - Encompasses the use of filamentous fungi to produce specialty chemicals and bioactive compounds - incorporates recent developments in the use of fungi for sustainable environment, waste management, and waste recycling into value added compounds - Highlights the benefits for future developments in the field of mycobiology

Enzyme Biotechnology for Environmental Sustainability discusses recent applications of enzyme biotechnology in various industrial sectors and state-of-the-art information on novel microbial enzyme technologies for a sustainable environment. The book describes in detail the latest developments and modern methods in microbial enzyme biotechnology for wider application in bioremediation, cleaner technology for industries and waste management, green chemistry and pharmaceutical biotechnology, sustainable textiles, food production and biodegradation, and other industries. The chapters cover topics such as genetic engineering, protein engineering, nanotechnological advances of microbial enzymes, computational tools for engineering enzymes, and health risk assessment of enzymes in different sectors. With contributors from an array of experts in the field, Enzyme Biotechnology for Environmental Sustainability is an informative reference for researchers, biotechnologists, microbiologists, environmental scientists, graduate and post-graduate students working in the area of enzyme technology and their biomedical, environmental, and industrial applications. - Includes new-methods and up-to-date information on modern methods with respect to its application in pharmaceuticals, textiles, food fermentation, and many other related fields - Provides in-depth information about the recent applications of enzyme biotechnology in different industrial sectors - Focuses on the rapid developments and biotechnological advances in microbial enzymology to enhance industrial and environmental sustainability

Bioreactor Design Concepts for Viral Vaccine Production covers a range of interdisciplinary chapters from the engineering perspective of bioreactor design to the biotechnological perspectives of vector design for vaccine development. The book covers bioreactor concepts such as static systems, single-use systems, stirred tanks, perfusion, wave and packed-beds. It reviews options for efficient and economical production of human vaccines and discusses basic factors relevant for viral antigen production in mammalian cells, avian cells, and insect cells. This book will be a great resource for those interested in implemented novel bioreactor design or experimental schemes towards intensified or/and enhanced vaccine production. - Covers the fundamentals of bioreactor designs - Provides strategies for designing a successful vector-based vaccine - Discusses the applications of biological kinetics, thermodynamics and basic substrate requirements for viral vaccine production

Linking Neuroscience and Behavior in COVID-19 examines the impact of the virus and pandemic on behavior and mental health. Chapters look at those with pre-existing conditions, including dementia and multiple sclerosis, and how the pandemic has burdened them further. There is also discussion on the mental health consequences the pandemic has had and continues to have on the broad populace, including depression and anxiety, as well as neurological effects of the virus itself. Finally, managing care and treatment of conditions - those preceding, caused by, or emerging for the first time during the pandemic are also detailed. - Discusses the impact of the COVID-19 pandemic and the virus itself on behavior and psychology - Examines comorbidities including Parkinson's disease, neuroinflammation, and autism spectrum disorders - Outlines the management and care for coexisting conditions including brain tumors, multiple sclerosis, and ischemic stroke - Features chapters on the severe damage to the nervous system which may be caused by SARS-CoV-2 infection including myelitis - Contains chapters with key facts, dictionary of terms, summary points, applications to other areas pertinent to each chapter, and policies and procedures

International and Life Course Aspects of COVID-19 describes the nuances and international variations of COVID-19 in different populations and age groups. This volume details those differences in chapters examining the effects of the virus at different life stages, including newborns, children, adolescents, and older populations. Consideration of the age-specific effects of COVID-19 on the brain are a major focus unique to this resource. International observations and global outcomes are also described. This volume is relevant for all clinicians working to ensure the best outcomes for patients with COVID-19 worldwide. - Examines COVID-19 symptoms and concerns according to age - Discusses outcomes related to global populations and differences observed in symptomatology and care - Focuses on the brain, with a look at developmental changes in pregnancy, newborns, childhood, and adolescence - Describes mental health impacts in the older populations - Features individual chapter introductions and summaries to provide a comprehensive introduction - Contains chapters with key facts, dictionary of terms, summary points, applications to other areas pertinent to each chapter, and policies and procedures

Features, Transmission, Detection, and Case Studies in COVID-19 examines the effects of the virus on the body, as well as its transmission and clinical profile. This volume begins with an introduction to the virus and its pathogenesis, transmission, and avoidance, followed by sections on pulmonary and cardiovascular effects, obesity, diabetes, the liver, detection issues, and biomarkers. Vaccines and treatment are also discussed. Specific case studies covered include hypoxia, acute kidney injury, pneumonia, and neurological effects. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19. - Discusses COVID-19 biology, including pathogenesis and transmission - Describes systemic issues caused by COVID-19, including cardiovascular effects and loss of taste and smell - Outlines detection methods, biomarkers associated with severity, and disease outcomes - Features individual chapter introductions, summaries, and case studies to provide comprehensive descriptions of COVID-19 symptoms and effects - Contains chapters with key facts, dictionary of terms, summary points, applications to other areas pertinent to each chapter, and policies and procedures

Advances in Virus Research, Volume 118 highlights new advances in the field, with this new volume presenting interesting chapters on topics such as HCMV-encoded GPCRs in infection, disease, and pathogenesis, Defense signaling pathways in resistance to plant viruses: crosstalk and finger pointing, and Pathogenesis of neuroinvasive flaviviruses. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in Advances in Virus Research series

Microbial Essentialism: An Industrial Prospective refers to properties specifically possessed by microbes such as secretion of metabolites which make them unique and can be employed by industries. These microorganisms can be commercially exploited for beneficial purposes such as the production of whole microbial cells or their products for direct use or as starting raw material in the manufacture of other commercial products which can contribute to large-scale and profit-oriented businesses.Microbial Essentialism: An Industrial Prospective reviews the newest techniques, approaches, and options in the use of microorganisms for the manufacture of industrially important products such as pharmaceuticals, industrial enzymes, chemicals, proteins, foods and beverages, and fuels. It covers fundamental principles of established and innovative industrial microbiology and biotechnology processes and products. It also discusses industrial microorganisms and the technology required for large-scale cultivation and isolation of fermentation products. - Covers key aspects of microbial physiology, exploring the versatility of microorganisms and their diverse metabolic activities and products - Provides methods and various traditional and novel applications of microorganisms to industrial processes - Contributed by a multidisciplinary group of experts who offer not only a thorough evaluation of the primary literature, but also invaluable first-hand experience in industrial microbiology and biotechnology

Recent Developments in Nanomaterial-Based Sensing of Human Pathogens gives insights into the alignment of recent developments in the field of nano-sensing of bacterial and viral pathogenic organisms. The book describes the role of biomarkers in the detection of fungal diseases and the importance of mycoplasmas in health and diseases that are naturally resistant to many common antibiotics, such as penicillin. Touching all areas of medical microbiology and analytical biochemistry, this book provides understanding to application-oriented microbial sensing concepts and updates knowledge with respect to recent advances on related aspects of pathogenic sensing. - Presents in-depth coverage of nanosensors for a wide range of human pathogens - Combines insights from nanotechnology, biology, and medicine for holistic pathogen detection - Shows cutting-edge progress in analytics, biomarker detection, and innovative nanodevices for improved pathogen sensing - Highlights clinical importance, serving as a valuable resource for pathogen detection and diagnostics

Endophytic Fungi: The Full Story of the Untapped Treasure covers the developments in endophytic fungal research from beginning to the end by the eminent researchers involved in the field. It sheds light on the endophytic fungal current research, challenges, and future possibilities, the trending recent topics in the plant-fungal endophytes'biodynamics for sustainable development of bioproducts and its applications are supported in large-scale biosynthesis of industrially and pharmaceutical important biomolecules.Endophytic Fungi: The Full Story of the Untapped Treasure highlights the bioprospecting and applied aspects of endophytic fungal communities from diverse hosts and discusses the practical applications of such endophytes in detail. It also reviews recent strategies on alternative sustainable sources of medicines such as secondary metabolites of fungi instead of over collection of plants under prohibiting of biodiversity conventions. The uniqueness of this book is the inclusion of updated bioinformatics-based strategies and its importance in bioactive molecules produced by endophytic fungi. The book addresses one of the most eminent issues in this field: how to translate the potential that endophytic fungi hold in stable practical application. - Covers major concepts of plant-fungi interaction, biodiversity of endophytic fungi from diverse and biotechnological applications for sustainable development - Is extensively illustrated and clearly written, using easy-to-understand language, sharing the latest developments and potential of fungal products for various applications - Sheds light on the endophytic fungal current research, challenges, and future possibilities

Entrepreneurship with Microorganisms explains both the basic science and applications of microbiology and bio-resource technology, shining a special emphasis on its entrepreneurial applications. By focusing on basic principles, current research, and global trends, this comprehensive book provides a critical resource and serves as a complete one-stop source for undergraduate and graduates in microbiology, food, agricultural science, medical science, and industrial microbiology biotechnology. In addition, this book will be helpful in the creation of economic (commercial) value of the microorganism(s) based products and technologies as well as opportunities for new jobs at the global level. - Provides a unique combination of both fundamental industrial microbiology and fermentation content - Includes protocols related to microbes (including fungi, bacteria and viruses) and its entrepreneurship, at a single plate form - Creates insights on how to make microbes monetizable for entrepreneurs who are in the state of confusion about the significance of biotechnology for public health and other bio-products like biofuels, food additives, and food quality improvement - Emphasizes the utilization of the beneficial aspects of microbes in the current scenario of the Covid-19 pandemic - Discusses different modern tools and techniques used for the study of microbial resources for the welfare of human beings

Nowadays, the field of microbiology is undergoing a revolutionary change due to the emergence of Artificial Intelligence (AI). AI is being used to analyze massive data in a predictable form, about the behavior of microorganisms, to solve microbial classification-related problems, exploring the interaction between microorganisms and the surrounding environment. It also helps to extract novel microbial metabolites which have been used in various fields like medical, food and agricultural industries. As the pace of innovation in Microbiology is accelerating, the use of AI in these industries will be beneficial. AI will not only show its extraordinary potential in expanding the market of antibiotics, food, and agriculture but also offer an eco-friendly, safer, and profitable solution to the respective industries. It would be challenging to search out specific features and discuss future research on AI in microbiology with a wide perspective. - Uncovering extended functions of AI in Microbiology. - Production and development of novel drug targets through AI. - Challenges for using and selecting appropriate AI tools in health, agriculture and food sector

Advances in Microbial Physiology, Volume 84 in this ongoing serial, highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Topics of interest in this update include Mycobacterial Efflux systems, New insights in bacterial organophosphorus cycling: from human pathogens to environmental bacteria, Link between gut sulfidogenic bacteria and disease, The Formate-H2 Axis and its Importance for Microbial Physiology, Physiology of diazotrophs, Antibiotic efficacy, and Microbial metabolites as modulators of host physiology. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in Advances in Microbial Physiology serial - Covers Mycobacterial efflux systems, New insights in bacterial organophosphorus, The link between gut sulfidogenic bacteria and disease, and much more

Advanced Biologic Drugs and Manufacturing Process explains biologic drugs, their pharmaceutical charters, and their significance in curing life-threatening chronic diseases. It also provides the latest information on the use of biological drugs for the treatment of numerous diseases and conditions and their most advanced therapies available, including how biologics have impacted cancer therapy, delayed or reversed the course of immune-related conditions, and changed the lives of those with rare chronic diseases. In addition, the book explains how immunotherapy is used for the treatment of diseases by activating or suppressing the immune system.Scientists working on the front lines in the biotechnology industry are provided with an overview on stable production processes and how to monitor the value chain transfer process of biologic drug for better return, in terms of profit. The book also helps researchers and academics on how to develop and update protocols related to testing, quality control, and quality assurance to obtain highly purified biopharmaceuticals or vaccines. - Gives insights into the conceptual strategic drive for manufacturing innovative, biologically derived therapeutic compounds to launch for commercial purposes - Focuses on how to execute biopharmaceutical portfolio trends to bring sustainable manufacturing processes per the guidelines of international regulatory acts - Highlights the emerging trends in medical sciences on tissue engineering, regenerative medicine, personalized medicines, and various innovative technique on immunotherapy to fight against life-threatening diseases

Pili in Mycobacterium Tuberculosis: Structure, Function, and Therapeutic Advances discusses the types of pili produced by the tuberculosis-causing bacterium, Mycobacterium tuberculosis (MTBC. The book examines the structure of pili shown under electron and atomic force microscopy and by using whole genome sequencing, outlines the importance of pili in mycobacterium tuberculosis. It also explores the role of pili in bacteria-host interactions and in drug development and delivery. Pili in Mycobacterium Tuberculosis opens with an overview of the structure, synthesis, and function of pili in bacteria. This includes taxonomy and the role of pili in diseases. The book also examines the preparation of Mycobacterium tuberculosis for electronic and atomic microscopy and looks at the different life cycles and susceptibility patterns of MTBC. It does on to discuss the expression and function of pili using whole genome sequencing and PCR-based methods and delves into bacteria host interactions. Lastly, it explores the development of new drugs and its delivery by pili. - Covers the structure, synthesis, and function of pili produced by the tuberculosis-causing bacterium, MTB - Introduces seven types of pili in MTB - Explains the mechanism of bacteria–host attachment and importance of this phenomena in MTB pili and other bacteria - Emphasizes the use of advances techniques to study and investigate the TB-bacilli and its interaction with host cells

Understanding the Pandemic: Pathophysiology, Transmission, and Treatment of COVID-19 aims to cover all aspects of COVID-19 infection from the virus, transmission, pathogenesis, immune-inflammation response, systemic injury, organ damage and associated factors comorbidities that drive mortality. Treatment protocols and the vaccination paradigm will also be discussed. Organized into ten sections, the book aims to provide a comprehensive examination of the impact of COVID-19. The book begins a review of coronaviruses, their structure and mechanism of action. The book goes on to discuss the immune response to the virus and its effect on various organs. It examines clinical cases based on an observations and postmortem studies. Other topics include the long-term effects of COVD-19, vaccines, and public health response. • Discusses coronavirus, their similarities and differences in origin and transmission as well as a review of their structure and mechanisms of action• Examines the immune-inflammation responses to COVID-19 and the organ-specific impact of the disease• Covers vaccines and other treatment protocols and public health responses in various geographic locations

Cutting edge technology-based drug delivery systems have been rapidly growing and are being applied to various sections of biomedicine. The current scenario of global burden due to infectious disorders can take advantage of nanoparticulate based carriers to advance the cure efficiency. Nanostructured Drug Delivery Systems in Infectious Disease Treatment explores a broad range of promising approaches for the treatment of infectious diseases using the latest advancements in nanomedical technologies. The book opens with introduction about infectious diseases and its global burden. There is also specific discussion and assessment of the global impact of viruses with an emphasis on COVID-19, Zika, and Ebola. Subsequent chapters provide detailed information about various novel nanotherapeutic strategies used for delivering drugs for the treatment of various types of viral, bacterial, and fungal disorders. Nanostructured Drug Delivery Systems in Infectious Disease Treatment is a valuable resource for graduates, researchers, industry professionals, and anyone working to tackle the challenges of delivering drugs in a more targeted and efficient manner for the treatment of infectious diseases. - Focuses on the application of different nanotechnology-based drug delivery systems - Offers information on how to design and develop the nanotechnology-based drug delivery systems and devices for the treatment of infectious disorders - Explores challenges and regulatory concerns of nanomedicine in infectious disorders

System Biology Approaches for Microbial Pathogenesis Interaction Analysis aids biological researchers to expand their research scope using piled up data generated through recent technological advancement. In addition, it also opens avenues for bioinformatics and computer science researchers to utilize their expertise in biological meaningful ways. It also covers network biology approaches to decipher complex multiple host-pathogen interactions in addition to giving valuable coverage of artificial intelligence. The host-pathogen interactions are generally considered as highly specific interactions leading to a variety of consequences. The utilization of data science approaches has revolutionized scientific research including host-pathogen interaction analyses. Data science approaches coupled with network biology has taken host-pathogen interaction analysis from specific interaction to a new paradigm of understanding consequences of these interaction in the biological network. Unfortunately, basic biological researchers are mostly unaware of these advancements. In contrast, data scientists are not familiar with biological aspects of such data. System Biology Approaches for Microbial Pathogenesis Interaction Analysis will bridge these gaps through a new paradigm of understanding consequences of interaction in biological networks. - Cover approaches to decipher complex multiple host–pathogen interactions - Gives biological researcher an insight into the utilization of technological advancements in the field of host–pathogen interaction analyses in their work - Provides a new paradigm of understanding the consequences of host–pathogen interaction in biological systems

Aquaculture Virology, Second Edition covers all the known virus families, and specific diseases that affect each aquatic organism. Descriptions of each disease includes disease name, structure and composition of virus, classification and virus replication, epidemiology, pathology and immunity, diagnostic methods (gross pathology, histopathology, cell culture, PCR, sequencing, ELISA, etc.) and prevention and control. This is an excellent reference of updated foundational and practical knowledge from experts in both academia and research.Those interested in fish viral diseases will find the book an excellent source for high quality illustrations of viral structure, diagrams of pathogenesis of diseases, and many images of gross pathology and histopathology lesions, using the same format in all chapters to facilitate the reading and studying. This second edition of the book will cover all virus families and the specific diseases relevant to aquaculture with current information delivered in a systematic and succinct way to the researcher, teacher, student, diagnostic laboratory staff, clinical veterinarian, aquaculture disease practitioner, farmer, and all people that are interested in viruses in general. - Provides unique, comprehensive information on animal pathogens and viruses found in aquaculture and fisheries - Presents high-quality illustrations of viral structure, diagrams of viral disease processes, gross pathology, and histopathology lesions to aid in understanding - Incorporates all updated changes in taxonomy since the first edition - Includes a new chapter on the impact of climate change on the manifestations of different aquatic animal viral diseases - Describes aquatic viruses of the major aquatic animals, fish, crustaceans, and mollusks

In recent years, there has been a global surge in the production and application of vitamins and pigments in food and pharmaceuticals industries, leading to draw the attention of scientific communities to develop novel strategies to cope with world demand. Microbial vitamins and carotenoids in food biotechnology: Novel source and potential applications allow the audience to understand the current status of the biotechnological approaches used for the production of vitamins and carotenoids from microorganisms. The title provides important insights to understand the molecular mechanisms involved in microbial biosynthesis of vitamins and carotenoids. The chapters, all written by leading researchers from academia, help to put forward all the latest advancement concerning the production and applications of microbial vitamins and carotenoids. The book also provides the sustainable alternative to chemically synthesized compound and presents the wide coverage for the most promising sources of vitamins and carotenoids in food and pharmaceutical industries. This is a complete and unique resource beneficial for the scientific communities as well as food science and nutrition research students. - Thoroughly explores biotechnological approaches surrounding the production and application of microbial vitamins and carotenoids in food processing and manufacturing industries - Covers the major portion of novel source and various biotechnological approaches used for the production of various types of vitamins and carotenoids from microorganisms and their applications in food industry - Contains up-to-date information required for the formulations of new products or protocols for enhancing production of specific compounds

Metabolomics for Personalized Vaccinology provides insight into the importance of personalized vaccines in the clinical and research environments. It explores the development of personalized vaccines, which requires in-depth knowledge of the patient's health status, particularly the immune system, and on metabolomics, the closest indicator of the disease phenotype. Specifically, the book provides an understanding of how metabolomics might be employed in personalized vaccinology and how the metabolic pathway of the host's system is altered by vaccine administration. Over the past few years, researchers have published articles on personalized vaccines, but these are sparse. Therefore, compiling information on this topic gives the reader an overview of the progress of the field, despite being at its infancy. Metabolomics for Personalized Vaccinology is ideally suited for researchers and postgraduate students who are interested in clinical and nonclinical studies where metabolites are used for the identification of disease and therapeutic targets. - Provides the principles of metabolomics and integration of other systems biology approach for personalized vaccine development - Discusses vaccine manufacturing technologies and importance of metabolomics for personalized vaccine development - Discusses the scope of personalized vaccine in relation to specific diseases - Possible scope of metabolomics in biomarker identification and vaccine discovery

As the field of genomics has progressed, our understanding of microbiology has also developed. With the advent of next-generation sequencing methods and advancements in instrumental resolution, complex transcriptome, proteome, and metabolome data could be analyzed, as well as detailed annotation of microbial genomes. Microbial Genomics: Clinical, Pharmaceutical and Industrial Applications focuses on the various applications of microbial genomics in clinical, pharmaceutical and industrial fields. It consists of four parts devoted to bacterial, viral, and fungal genomics, as well as their applications in clinical, pharmaceutical, and industrial fields. Chapters are written by experts in their respective disciplines and are tightly organized with an introduction to detailed descriptions, available software implementation, applications, advanced topics, summaries, analytic questions, exercises, and suggested readings. Throughout this book, the latest genomics and biotechnological developments and discoveries as well as open problems and future challenges on microbial genomics will be highlighted. Readers will be introduced to state-of-the-art developments and trends of microbial genomics, its clinical, pharmaceutical, and industrial applications. The book will be beneficial for researchers who study microbial genomics in universities, post-graduate and graduate programs (biology, biotechnology, medicine, genetics, microbiology, industrial and environmental microbiology, etc.), as well as the pharmaceutical and industrial sector. - Presents the recent genomic developments in the industrial applications of microorganisms - Summarizes recent developments in microbial genomics, emphasizing the role of next-generation sequencing in functional genomics - Focus on how transcriptomics can help better understand host responses to pathogen infection - Describes applications of genomics in clinical microbiology

Modernizing Global Health Security to Prevent, Detect, and Respond explores—through thoughtful, thorough, and diverse scientific review and analyses—factors that have led to recent public health emergencies and offers a vision for a better protected global environment. The authors consider the history of global health security, governance, and legal structures with an eye toward novel approaches for the present and future. The book presents a vision for a more protected and safer global public health future (with the actions needed to achieve it) to prevent, detect, and respond to (re)emerging threats. Its aim is to chart a way forward with the understanding that future pandemics must and can be prevented. Major topics examined from a public health perspective include global health security; the growing concept of One Health; epidemic and pandemic prevention, detection, and response; reviews of past (e.g., Ebola, MERS-CoV, Zika, and COVID-19) public health emergencies of international concern; roles of information and communication technology; humanmade public health threats; and legal and ethical issues (e.g., viral sovereignty, trust, and transparency). Modernizing Global Health Security to Prevent, Detect, and Respond provides the academic substance and quality for researchers and practitioners to deeply understand the why of health emergencies, and most importantly—what we can and should do now to prepare. - Highlights (re)emerging past and future threats to public health (e.g., climate change, antibiotic resistance, failures of societal sectors to work together) - Discusses new visions for global health security in each chapter - Considers how to leverage technological innovations to advance public health - Includes practical examples through case studies from around the world

Diagnosis and Analysis of COVID-19 using Artificial Intelligence and Machine Learning-Based Techniques offers new insights and demonstrates how machine learning (ML), artificial intelligence (AI), and (Internet of Things (IoT) can be used to diagnose and fight COVID-19 infection. Sections also discuss the challenges we face in using these technologies. Chapters cover pathogenesis, transmission, diagnosis, and treatment strategies for COVID-19, Artificial Intelligence and Machine Learning, and Blockchain /IoT Blockchain technology, examining how AI can be applied as a tool for detection and containment of the spread of COVID-19, and on the socioeconomic and educational post-pandemic impacts of the disease. This is a multidisciplinary resource for those engaged in researching COVID-19 and how emerging technologies are being used as tools for detection, transmission and treatment strategies. - Describes the molecular basis of pathogenesis, epidemiology, transmission mechanism, diagnostic approaches, and the mutational landscape of SARS-CoV-2 - Provides insights into post COVID-19 symptoms and consequences - Demonstrates how machine learning, AI, and IoT is used to diagnose and fight COVID-19 infection - Examines the use of Blockchain technology/IoT and interpretation and validation of data obtained from artificial intelligence

An Introduction to the Microbiome in Health and Diseases covers the compositional structure and roles of the human microbiome in health and disease. Sections discuss and foundational content, from bench to bedside in microbiology to trigger more in-depth knowledge and provide updated findings on today's hottest topic–the microbiome. The book translates current findings of studies into clinical practice. Other sections give updates on the role of microbiome in health and several diseases, the impact of diet, exercise and gut microbiome, the plant microbiome, non-infectious environmental agents and autoimmunity. - Provides fundamental coverage on the microbiome and its effect on human health and diseases. - Describes procedures for sampling small and larger samples of the microbiome. - Discusses patents, bioproducts, commercialization, and the social, ethical and economic implications of the microbiome.

Viral Diseases of Field and Horticultural Crops details the fundamental and applied aspects of the viral diseases of field and horticultural crops. The book opens with a historical introduction to plant virology, important plant virologists, and landmarks. It continues with systematic coverage of viral diseases, their economic significance, disease symptoms, host range, mode of transmission, diagnostic techniques, geographic distribution, epidemiology, yield losses, and control and management of the disease. Contributions from an international group of virologists with a wide range of academic, research, professional, and specialized backgrounds in plant virology makes Viral Diseases of Field and Horticultural Crops a comprehensive and must-have resource for those engaged in the study and research of plant virology, microbiology, and plant pathology particularly viral diseases and their impact on field and horticultural crops. - Provides virus characterization according to the disease pattern and symptoms they cause - Covers viral diseases of cereals, oil seeds, legumes, commercial crops, spices and condiments, medicinal and aromatic crops, forage crops, vegetable crops, fruit crops, tree nuts, among others - Discusses advances like applications in nanotechnology, molecular techniques for the detection and characterization of plant viruses, and the development of technologies for detecting plant viruses

The Potential of Microbes for a Circular Economy provides a thorough understanding of the role of microbes in a circular economy (CE). It covers the development of effective bio-based formulations for field applications and describes the basic principles and applications of the circular economy, the important role of microorganisms, and new insights into a sustainable ecosystem.The Potential of Microbes for a Circular Economy compiles the latest advancement in the field of CE by covering the aspect of microbes and microbial products providing microbiologists the tools to engage with the wider public, policymakers and industry to inform the debate on addressing current challenges and showcasing the positive impacts of microbiology for society. - Provides a thorough understanding on the role of microbes in the circular economy that can help to develop effective bio-based formulations for field applications - Describes the basic principles and applications of the Circular Economy - Gives insights on the important role of microorganisms explored in the circular economy, which in turn provides new insights into the sustainable ecosystem

Functional Metagenomics: Microbial Diversity, Interaction, and Application in Bioremediation uses a 20-chapter, easy-to-understand format to centralize the practical application ideas for functional metagenomics. This important resource not only includes chapters on next-generation sequencing technologies to study important biogeochemical cycles, degradation pathways and detoxification, but also gives insight into several tools that have been developed to integrate metadata and sequence data, allowing downstream comparative analyses of different datasets using several ecological indices.Content further explains the newly developed techniques for sequencing DNA; generating shorter fragments than Sanger sequencing techniques to quickly read larger sequences in a shorter amount of time. The content finally explores the role of metagenomics in studying microbial diversity, interaction and application in bioremediation studies and gives the reader overall detailed information regarding metagenomics, its application as well as techniques. - Provides comprehensive information to readers on state-of-the-art applications in metagenomics - Summarizes our current knowledge of the use of metagenomics and gives a novel and powerful insight into the already existing bioremediation process - Gives an overall picture of metagenomics, its application, processes, and future prospects in the field of bioremediation

Microbiome Drivers of Ecosystem Function focuses on the advancements in microbial technologies towards harnessing the microbiome for improved crop productivity and health that are at the frontier of agricultural sciences. It provides insights into the diversity of endophytic microbiomes and their potential utility in agricultural production.Increased crop yield through chemical interventions have limit thresholds and alternative, natural and/or integrated approaches are increasingly needed. Microbial inoculants among the ways in which food production efficiency can be improved. Plant growth-promoting soil organisms increase net crop uptake of soil nutrients, resulting in larger crops and higher yields of harvested food. These and other symbiotic associations between plants and microbes can ultimately be exploited for the increased food production necessary to feed the world, in addition to creating safer farming techniques that minimize ecological disruption.As a volume in the Microbiome Research in Plants and Soil series, Microbiome Drivers of Ecosystem Function serves as an ideal reference for researchers and students in the fields of agricultural biotechnology, biochemistry, environmental science, plant biology, agricultural sciences, and agricultural engineering. - Provides insights on engineered microbes in sustainable agriculture, recent biotechnological developments, and future prospects - Introduces microbes as chief ecological engineers in reinstating equilibrium in degraded ecosystems - Presents the current state and development, as well as future challenges in studying plant-microbe interactions - Discusses endophytic microbiomes and other microbial consortium with multifunctional plant growth-promoting attributes

Advances in Virus Research, Volume 117, the latest release in a series that highlights new advances in the field, includes invaluable updates written by an international board of authors. Chapters in this new release include Pathogenesis of neuroinvasive flaviviruses, Cellular entry and egress of astroviruses, Rift Valley Fever virus entry and infection, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in Advances in Virus Research serials

Aeromicrobiology provides a detailed and systematic analysis of the microbial communities and toxins collectively called bioaerosols that can be found in air. It provides information on the basics of Aeromicrobiology, the fate and transport of microorganisms in air, and the fundamental differences between intramural and extramural Aeromicrobiology. Leaning heavily on the current state of science, detailed information on the sampling and analysis of bioaerosol samples is provided. Subsequent chapters comprehensively discuss various airborne microbial groups and toxins, while the final chapter is dedicated to bioaerosol control strategies, biosafety, and biosecurity. There are limited resources on Aeromicrobiology. In rare instances where there are resources on Aeromicrobiology, they are often restricted to chapters in books or even supplementary materials. The emergence of new airborne pathogens, the aerosolization of microorganisms hitherto believed not to be airborne, and the proliferation of technologies for sampling, analysis, and control of bioaerosols makes it imperative for this title, which streamlines and succinctly presents the new body of knowledge in the field. - Leans heavily on current state-of-the-art technologies used in sampling and analysis of bioaerosol samples such as metagenomics and sensor-based, hybrid technologies, among others - Dedicates considerable attention to airborne and droplet-borne viruses, against the background of SARS-CoV-2 and related pathogens - Comprehensively attends to regulatory aspects of bioaerosol control, highlighting various policies and regulations aimed at achieving biosecurity and curbing bioterrorism - Helps researchers and policy makers in various fields who are often confronted with the need for basic information delivered in seamless style without loss of essential content

Antimicrobial Peptides: Challenges and Future Perspectives covers the latest developments about antimicrobial peptides in the scenario of drug resistance. The book is divided into 16 chapters arranged in sequence and preceded by chapters on historical developments and their role as regulatory molecules in innate defense mechanism. Emphasis is given to purification techniques and characterization suitable for interdisciplinary research. Chapters provide an inventory of various antimicrobial peptides, from a diverse array of organisms such as bacteria, fungi, insects, amphibians, plants and mammals. A section on marine ecosystem broadens readers understanding on marine based antimicrobial peptides. Additional sections provide an informative overview on peptides with antiviral properties and those targeting multi-drug resistant bacteria. Recent reports and mechanism on resistance against antimicrobial peptides are also provided, along with key insights into the challenges and future perspectives of peptide drug development. - Emphasizes antimicrobial peptides targeting various human viruses and multidrug resistant bacteria - Written by internationally recognized experts who provide readers with a wide and useful perspective - Provides in-depth resources for undertaking a research work in antimicrobial peptides with the inclusion of chapters on purification techniques and structural details - Addresses the possibility and availability of peptide antibiotics in the global drug market - Serves as a complete resource from the discovery to drug development of peptide antibiotics

Material-Microbes Interactions: Environmental Biotechnological Perspective brings great insights into microbes-material interactions, biofilm formation and emerging bioprocesses within the field of applied biotechnology. The book systematically summarizes the fundamental principles, the state-of-the-art in microbes-material interaction, and its application in bioprocess and environmental technology development. Understanding the fundamental processes of biofilm formation, the role of material to exchange the energy with microbes, biofilm matrix, and optimization of the biofilm formation process is useful to everyone involved with bioprocess development. This book will be of significant interest to environmental technology developers, researchers, university professors, policymakers, graduate and postgraduate students and other stakeholders. Interestingly, academic institutions, wastewater treatment plants and research centers have upscaled biofilm-based environmental technologies, such as moving bed bioreactors, microalgae, tricking bed reactors, biofilters, and bioelectrochemical process as promising environmental technologies. - Illustrates growing interest in biofilm-based technology development, either wastewater treatment using carrier materials or valorizing waste material into resources using biofilm-based bioprocess - Focuses explicitly on the microbes-material interactions in various biotechnologies - Covers a broad range of biofilm-based bioprocesses, including new and state-of-the-art options and trends within the field - Includes photo-sets on biofilm development and bioreactor systems

Plant RNA Viruses: Molecular Pathogenesis and Management provides wide-ranging coverage on the recognition and signaling events between plants and RNA viruses. The book examines the molecular biology of signaling, host-virus interaction, RNA virus diversity, and how plants and cellular pathogens interact. Sections cover Virus Diversity and Diagnosis, Virus-Host Interactions and Virus Management. Specific chapters discuss classification and nomenclature of viruses, detail the molecular characteristics of viral genomes, highlight the viral manipulation of cellular key regulatory systems for successful virus infection, and discuss the movement of plant viruses into plant cells. Additional topics include RNA plant viruses and host interaction, detection and diversity of plant RNA viruses, and strategies for combating and management of plant viruses. With contributions from an international group of experts, the book is a comprehensive reference for those in research, academia, industry and anybody engaging in the study of plant viruses at the molecular level. - Provides an overview of virus genome and nomenclature - Covers plant virus biodiversity and ecology, diversity mechanisms and opportunities - Examines Plant Host-Virus Interaction - Discusses virus-vector interaction and transmission - Offers strategies for virus management, both traditional and modern

Viral, Parasitic, Bacterial, and Fungal Infections: Antimicrobial, Host Defense, and Therapeutic Strategies highlight diverse types of infections, including viral, bacterial, parasitic, fungal, and the therapeutic efficacy of antibiotics, antivirals, antifungals and other medications, nutraceuticals, and phytotherapeutics. This book addresses the molecular, pathophysiological, and cellular pathways involved in the process of infection. It also examines the host defense mechanisms modulated by innate and adaptive immunity. The book starts off with an introduction, which includes etiology, pathophysiology, and diagnosis of infections. It then goes on to cover a wide spectrum of salient features involved in viral, bacterial, parasitic, and fungal infections and effective therapeutic strategies. In addition, there is a complete section of eight chapters elaborating the detailed aspects of COVID-19 infections, Mucormycosis, Omicron, and strategic vaccines and therapeutics. The book further goes on to discuss novel antibiotics, vaccines, bromhexine, boron compounds, phytotherapeutics, and aspects on boosting immune competence. Contributed by experts in the fields of viral, parasitic, bacterial, and fungal infections, the book comprehensively details the various types of infections such as herpes and COVID-19, their molecular mechanisms, and treatment strategies for those engaged in the research of infectious diseases. - Details the pathophysiology of various classes of infections - Examines mechanisms of pathogenesis, immunity, and therapeutics in bacterial, viral, and eukaryotic infectious diseases - Discusses various aspects on herpes, COVID-19 infections, Mucormycosis, Omicron, vaccines, and therapeutics - Covers the salient features on zoonosis, prion disease, and diabetic foot infections - Provides therapeutic strategies of using new antibiotics, vaccines, bromhexine, boron compounds, structurally diverse phytotherapeutics, immune enhancers, and other modalities for treating infections

Emerging Technologies in Applied and Environmental Microbiology describes various problems and solutions that arise in applied and environmental microbiology using scientific technologies. The book summarizes the main omic-based methods currently used to characterize environmental microorganisms, as well as approaches to analyzing and interpreting the bio information generated by experimentally based studies. Sections explore the current understanding of bacterial signaling through examples of communication systems that include signaling in gram-positive and gram-negative bacteria, along with discussions on how microorganisms interact with each other, with other organisms, and with the environment. In addition, this comprehensive resource highlights the importance of various emerging technologies for cleaning up pollution in the environment caused by human activities. Final sections assess the potential application of several existing, applied and environmental microbiological techniques and introduces new and emerging technologies through applied aspects. - Describes various problems and solutions that arise in applied and environmental microbiology using scientific technologies - Summarizes the main omics-based methods currently used to characterize environmental microorganisms, as well as approaches to analyzing and interpreting the bio information generated by experimentally based studies - Explores the current understanding of bacterial signaling through examples of communication systems that include signaling in gram-positive and gram-negative bacteria - Shows the presence of all kinds of microbes in the natural environment for the removal of organic pollutants through various emerging technologies

Laboratory Methods in Microbiology and Molecular Biology describes various microbiological, biochemical, and molecular methods employed for the characterization, identification, and analysis of actinomycetes, bacteria and fungi. The book details general guidelines, expectations, and responsibilities for good lab practices and consists of chapters that covers basic microbiological, physiological, biochemical, and molecular aspects as well as in silico analysis using various bioinformatic tools. Other topics in the book include how to make solutions, microscopy and imaging of microorganisms, sero-diagnostics, and basic concepts of phylogeny, physiology, biotechnology, soil, food, and environmental microbiology while working in laboratory. Laboratory Methods in Microbiology and Molecular Biology is an informative update to current practices and future perspectives for the field of microbial biotechnology. It aims to facilitate professors, researchers, and graduate students in monitoring the precision and accuracy of the qualitative and quantitative methods in their research. - Involves various procedures in diverse disciplines, from microbiology to genetics, molecular biology and biochemistry - Lists the principles and facts underlying practical applications of bacteria and fungi which have prospects in various technologies - Includes the questions'how'and'why'as an explanation for novice students and researchers to modify protocols - Facilitates students, teachers and researchers to monitor the precision and accuracy of their qualitative and quantitative methods practically

Algae Materials: Applications Benefitting Health offers a comprehensive analysis of biosensors, algae materials for clinical applications, algae polymers, proteins and pigments, algae for food applications and packaging, blue economy, algae forming, cosmetics, and more. The book enlists the less explored areas of algal bioproducts, including how the application of genetic engineering is currently used to enhance bioproducts. Even though there are numerous reviews and scattered documents available, there are some recent fields yet to explore. - Offers a comprehensive analysis of biosensors, algae materials for clinical applications, algae polymers, proteins and pigments, algae for food applications and packaging - Enlists the less explored areas of algal bioproducts like how applications of genetic engineering are used to enhance bioproducts - Includes recent findings and often excluded areas in microalgae research available in a single source

Advanced Microbial Techniques in Agriculture, Environment, and Health Management provides current perspectives on the fields of agriculture, the environment and health. This important reference presents recent advancements in applied microbial technology, compiling it in a comprehensive manner and transferring applied microbial technology from laboratory conditions to field level. In 20 chapters, the book focuses on microbial interventions for all-inclusive, cost-effective environmental management tactics while also linking the cumulative microbial services involved in the up-gradation of agriculture, environment and health. In addition, the book offers detailed information on emerging environmental issues and proposes ways of controlling their consequences using different approaches to treatment. - Provides conceptual information and recent advances in microbial services involved in enhancing environmental sustainability - Offers potential solutions for a variety of problems like low agricultural productivity, emission of harmful contaminants from both natural and anthropogenic sources, and disease development in plants and humans - Contains applied, in-depth knowledge on microbial contributions as bio-inoculants, enzymatic sources and antimicrobials

Advanced Microbial Technology for Sustainable Agriculture and Environment focuses on plant-microbe interactions in respect to bioremediation and plant growth promotion, providing insights on diverse approaches such as genomics, metagenomics, proteomics, bioinformatics and other high-throughput analyses of environmentally relevant microorganisms. The impact of frequent applications of potentially toxic chemicals (pesticides and fertilizers) and increased industrialization processes on microbial diversity emphasizes the potential threat to microbial biodiversity in ecosystems. This is an ideal resource on current trends and the future of PGPR developments with bioremediation potential.Moreover, it gives a deep understanding of the genetics of microbial biodegradation and different remediation mechanisms that help to re-establish the natural environment. - Helps readers find sustainable ways for environmental clean-up and increased agricultural productivity - Gives a systematic overview of the role of PGPR in bioremediation, selection and preparation of potential PGPR microbial inoculum for bioremediation, biodegradation and plant growth promotion - Illustrates the importance of PGPR in the bioremediation of potentially hazardous and relatively novel compounds with the maintenance of sustainable agricultural productivity - Addresses emerging novel approaches of PGPR-based biodegradation of toxic compounds and highlights key developments and challenges associated with the processes

••Selected for Doody's Core Titles® 2024 in Microbiology••Understanding Microbial Biofilms: Fundamentals to Applications focuses on the microbial biofilms of different environments. The book provides a comprehensive overview of the fundamental aspects of microbial biofilms, their existence in nature, their significance, and the different clinical and environmental problems associated with them. The book covers both the fundamentals and applications of microbial biofilms, with chapters on the introduction to the microbial community and its architecture, physiology, mechanisms and imaging of biofilms in nature and fungal, algal, and bacillus biofilm control. In addition, the book highlights the molecular and biochemical aspects of bacterial biofilms, providing a compilation of chapters on the bacterial community and communication from different environments. Finally, the book covers recent advancements in various aspects of microbial biofilms including the chapters on their biotechnological applications. All the chapters are written by experts who have been working on different aspects of microbial biofilms. - Illustrates fundamental aspects surrounding microbial biofilms, along with recent advancements - Provides an overview on the principal aspects of biofilms, i.e., formation, regulation, distribution, control, and application - Updates on the progress on biofilm regulation through'omics'- Serves as a classical manual for all researchers, academicians, and students who would want complete insights on biofilms in a single resource - Covers all recent advancements and amendments on microbial biofilms

In the recent past, beneficial microorganisms have been sustainably used in agriculture as a safe, economic, and effective alternative to chemical fertilizers or pesticides. These beneficial microbes, including bacteria, actinomycetes, and yeast, were efficiently applied in soil, seeds, fruits, or plants as inoculants, to achieve the optimum agricultural yield.An efficient delivery method or enhanced shelf life of microbial inoculants in the soil or seed is still a matter of concern. The response of local genetic or ecological factors, after microbial applications, are also unknown and less studied. Therefore, Microbial Inoculants: Recent Progress and Applications fulfills the need to explore and learn about an efficient delivery mechanism, selection of microbial strain as inoculants, and related technological advances, for the efficient and productive use of microbial inoculants. Moreover, factors like methods of formulation, interaction between host plant and microbe, impact of inoculation on the metabolomics of plants, the effect of microbial inoculants on soil dynamics, proteomics approach of plant-microbe interaction, as well as the registration and regulation process of bio inoculants for commercial production are described in 16 chapters by the leading academicians and researchers from different parts of the world. - Sums up the latest approaches and advancements in the field of microbial inoculants in microbial formulations and applications. - Proofs the potential development and applications of microbial inoculants as an alternative to chemical fertilizers, herbicides and pesticides. - Shows the impact of microbial inoculants on microbial dynamics, bioavailability and abiotic stress mitigation. - Gives insights on emerging challenges with the commercialization of microbial formulations, technology patenting and legal perspectives.

Unravelling Plant-Microbe Synergy focuses on agriculturally important microorganisms (AIM's) that are indigenous to soil and roots of the plant. These microbes contributing to nutrient balance, growth regulators, suppressing pathogens, alleviate stress response, orchestrating immune response and improving crop performance as they are offering sustainable and alternative solutions to the use of chemicals in agriculture. As plant microbe synergy is an enthralling subject, is multidisciplinary in nature, and concerns scientists involved in applied, and environmental microbiology and plant health and plant protection, Unravelling Plant-Microbe Synergy is an ideal resource that emphasizes the current trends of, and probable future of, microbes mediated amelioration of abiotic and biotic stress, agriculture sustainability, induced systemic tolerance and plant health protection. Unravelling Plant-Microbe Synergy discloses the microbial interaction for stress management and provides a better understanding to know the recent mechanisms to cope these environmental stresses. Unravelling Plant-Microbe Synergy bridges the gap in recent advances in the microbes interaction and rhizosphere engineering. - Emphasizes the plant microbes interactions, induced systemic tolerance, stress responsive genes and diversity of microorganisms - Illustrates the current impact of climate change on plant productivity along with mitigation strategies - Provides a two-way interactive approach to both plants and microbes, and includes multi-omics approaches

The excessive use of antibiotics has given rise to an increase in microbial resistance, threatening our ability to treat infectious diseases. The growth in resistance to antimicrobials and antibiotics threatens to reverse almost a century of medical progress. urgent action plans to tackle the crisis of Antimicrobial Resistance (AMR) and multi-resistant bacteria are needed. It is a major research task to find effective ways to reduce the release and degradation of antibiotics and ARBs to the environment. Degradations of Antibiotics and Antibiotic Resistance Bacteria from various sources addresses various issues related the generations and degradations, eliminations of antibiotics and antibiotics resistance bacteria. Degradations of Antibiotics and Antibiotic Resistance Bacteria from various sources contains both practical and theoretical latest and broad aspects of antibiotics and antibiotics resistance bacteria management through the various recent methods. Various factors which are responsible for the efficient degradations are highlighted in the Degradations of Antibiotics and Antibiotic Resistance Bacteria from various sources as separate chapters. Socioeconomic and policies on the ARBs are also discussed. - Contains both practical and theoretical latest and broad aspects of antibiotics resistant bacteria - Emphasizes the health impact of antibiotic resistance and genes - Gives insight in the applications of anaerobic digestions for eliminations of ARBs (antibiotic resistance blockers) and ARGs (Antibiotic Resistance Genes) - Shows how ARB's influences the degradation processes and management

Metabolomics: A Path Towards Personalized Medicine integrates environmental factors of genomics, transcriptomics and proteomics, providing a bridge to resolve gaps between fundamental science and applications in clinical medicine and population health. The concept of personalized medicine or precision medicine is of great interest in biomedical research as it helps bring about new drug discovery and biomarker identification. In addition, it helps clinicians prescribe the right medicine to the right person with maximum efficacy and minimum toxicity, allowing clinicians to further predict the susceptibility to disease onset of vulnerable populations.The book is ideally suited for researchers and postgraduate students who are interested in clinical and non-clinical studies where metabolites are used for the identification of disease and therapeutic targets. - Gives insights on the importance of personalized medicine in clinical and research environments - Provides the principles of metabolomics - Presents applications of metabolomics in biomarker identification and drug discovery

Basic Biotechniques for Bioprocess and Bioentrepreneurship deals with the entire field of industrial biotechnology, starting from the basic laboratory techniques to scale-up, process development, demonstration, and finally its commercialization. The book compiles currently scattered materials on this topic and updates this information based on practical experience and requirements. The book will be an ideal source for new entrepreneurs who wish to start their own commercial units. - Offers guidance for readers/researchers/start-ups/entrepreneurs on how to develop new microbiological and biotechnical processes - Focuses on basic knowledge and possible solutions to the practical difficulties at all levels in one place through understanding of basic techniques in lab, during bioprocess development, commercialization, technology transfer, marketing, and others which is presently not available in the field - Provides multifaceted coverage, with industry insights from experienced practitioners and leaders in the field - Gives possible best solutions to the practical difficulties at all levels, i.e. lab, scaleup, and commercial stage - Addresses ethical and other regulatory issues