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Phytoconstituents are a valuable source of new lead compounds due to their structural variety.The accelerated rate of human ageing brought about by the 21st century's longer life expectancy seems to be one of the major problems facing varied cultures worldwide. Ageing and the onset of chronic diseases appear to be significantly influenced by the type of food consumption pattern that people follow throughout their lives. There is strong evidence that Mediterranean diets are linked to a lower risk of brain disorders. A greater proportion of rural communities in the Mediterranean basin eat a diet high in plant-based foods daily. Stressors like reactive oxygen and reactive nitrogen species have a major negative influence on the brain in addition to the cardiovascular system.Foods, particularly those derived from plants, are a great source of vitamins, antioxidants, polyphenols, and vital fatty acids, according to a growing body of epidemiological research. Studies indicate the effect of antioxidant vitamins on brain health, including ascorbic acid and α-tocopherol. Polyphenols and other plant-derived bioactivities influence how animal and human brains operate by reducing the amount of oxidative stress and controlling different signal transduction pathways, according to a large body of experimental evidence.The present volume provides a collation of recent developments in the field with special reference to various types of plant-based phytoconstituents. The book's content is relevant and interesting to a wide range of audiences from the backgrounds of plant sciences, pharmacy, biochemistry, and molecular biology. Apart from being a good reference material source, the book is relevant to plant biotechnologists and students/researchers in the field.

Ageing is the main reason for most neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD). About 10% of individuals aged ≥65 years develop AD, which continuously increases with growing age. Medicinal plants have been used for age-related neurodegenerative disorders for a long time. These plants are rich in terms of various phytochemical constituents such as flavonoids, sterols, alkaloids, saponins, and terpenoids. Different scientific studies have been carried out on these medicinal herbs, e.g., anti-inflammatory, antioxidant, and neuro-regenerative activities that may be used in the treatment of AD and other age-related diseases. These medicinal plants, e.g., Curcuma longa, Bacopa monniera, Glycyrrhiza glabra, Commiphora whighitti, and Acorus calamus L., have anti-inflammatory properties that may decrease swelling of the brain tissue in AD.Despite this, there is currently no book available in the market that provides full information on the phytochemical and medicinal uses of the medicinal plants exclusively used for the management of neurodegenerative diseases in the elderly. This book aims to provide some important and evidence-based information on the plants used for neurodegenerative diseases in the elderly, especially AD and PD, in a planned manner so the academicians, researchers, and students working in the fields of medicinal plants, plant science, chemistry, biotechnology, pharmacognosy, pharmaceuticals, biochemistry, and many other interdisciplinary subjects may benefit. This book will also be useful in identifying a few medicinal plants and their prospects for the synthesis or preparation of new drugs for neurodegenerative diseases.Features: An overview of the medicinal plants that can be helpful for neurodegenerative disorders Recent research results and some pointers for the management of neurodegenerative diseases This book serve as comprehensive information about the description, phytochemistry, actions, and medicinal use of plants that are used in neurodegenerative diseases. In addition, this book will also ease the understanding and interaction of medicinal plants used in neurodegenerative diseases.

This new 2-volume set aims to share and preserve ethnic and traditional knowledge of herbal medicine and treatments, while also emphasizing the link between biodiversity, human nutrition, and food security. Ethnic Knowledge and Perspectives of Medicinal Plants is divided into two volumes, with volume 1 focusing on the traditional use of curative properties and treatment strategies of medicinal plants, and volume 2 addressing the varied nutritional and dietary benefits of medicinal plants and the practice of Ayurveda. Both volumes stress the importance of bioresources for human nutrition and nutraceuticals based on ethnic knowledge and the need for efforts to protect biodiversity in many regions rich with medicinal plants.Exploring the benefits of medicinal plants in disease prevention, treatment, and management, Volume 1 discusses the traditional use of medicinal plants as promising therapeutics for cancer, liver conditions, COVID-19, and other human ailments. It examines the efficacy of Ayurvedic and Chinese herbal medicine, Indian traditional medicine, and other ethnic herbal practices used by indigenous peoples of Azerbaijan, South America, Turkey, India, etc. A variety of plants are discussed, and the ethnomedicinal applications of over 100 wild mushrooms for their medicinal and healthcare purposes are elaborated on.While volume 1 focuses primarily on natural plant resources for addressing specific health issues, volume 2 looks at traditional medicinal plant use for their nutritional and dietary benefits, while also encouraging the preservation of biodiversity for healthy and sustainable diets. The volume presents information on over 2200 vascular plant taxa from 127 families as well as many taxa from leaf parts, fruits, underground parts, floral parts, seeds, and more that have potential use as edible food plants. Ethnic knowledge on the wild edible mushrooms is an emerging area, which is unique and is dependent on the folk knowledge of tribals; this volume discusses the unique nutritional attributes of wild edible mushrooms (206 species belonging to 73 genera) in Southern India. The authors look at various lichens as nutritional aids and medicine and as flavoring agents and spices. Fucoidans derived from the seaweeds (and spirulina) are described for their antioxidant activity, nutritional and anti-aging properties, antiviral activities, anti-cancer properties, anti-diabetic properties, and more. The authors also examine how ethnicity affects healthcare/nutritive systems at different levels through various dynamics such as lower income, inability for services uptake, disputes among different ethnic groups, cultural attitudes (some ethnic group are vegetarian), lack of socio-economic resources, and disease prevalence.Together, these two important volumes aim to preserve and disseminate the valuable ethnic knowledge of medicinal plants gained over thousands of years and to promote the value of integrating and safeguarding biodiversity.

This new volume discusses the valuable contribution of immune-boosting properties of nutraceuticals and functional foods toward human health, exploring dietary antioxidants, vitamins and minerals, edible microalgae, herbs, phytonutrients, omega 3-fatty acids, and probiotics. The volume addresses the immune-boosting properties of herbs and vegetables and the pharmacological and therapeutic importance of commonly used medicinal herbs and carotenoids-containing vegetables and their immunological and biological actions for treating disease and maintaining health. Several chapters focus on marine-derived sources used to boost immunity, such as microalgae-derived compounds and compounds from coral reefs, which can promote better health and alleviate the risk of development of degenerative diseases.

This book provides scientific reports on the therapeutic potential of medicinal plants using animal models and provides information on the beneficial role of medicinal plants on human diseases. It looks at a number of medicinal plants and examines the medicinal properties and activities of the plants for a variety of health issues, such as for diabetes, cardiovascular disease, neurodegenerative disease, organ dysfunctions, cancer, labor and postpartum issues, and more. The therapeutic mechanisms of some phytoconstituents are also discussed.

Alzheimer's disease, one of the most rapidly growing neurodegenerative disorders, is characterized by a progressive loss of memory. Despite several advances in the field of medical therapeutics, a viable treatment for Alzheimer's disease would be of great importance. Medicinal plants represent a largely untapped reservoir of natural medicines and potential sources of anti-Alzheimer's drugs. The structural diversity of their phytoconstituents makes these plants a valuable source of novel lead compounds in the quest for drugs to treat Alzheimer's disease. Based on traditional literature and up-to-date research, various new therapeutically active compounds have been identified from phytoextracts, which could be useful in the treatment of cognitive disorders.Phytomedicine and Alzheimer's Disease presents information on Mechanistic aspects of neurodegeneration in Alzheimer's disease and the role of phytochemicals as restorative agents Understanding the complex biochemical aspects of Alzheimer's disease Pre-clinical approaches to evaluating drugs to target Alzheimer's disease Assessing alternative approaches to treating Alzheimer's disease and the role of alternative medicine to delay the symptomatic progression of this disease Epigenetic changes in Alzheimer's disease and possible therapeutic or dietary interventions This book serves as an excellent resource for scientific investigators, academics, biochemists, botanists, and alternative medicine practitioners who work to advance the role of phytomedicines in treating Alzheimer's disease.

The enormous advances in nanomedicine and precision medicine in the past two decades necessitated this comprehensive reference, which can be relied upon by researchers, clinicians, pharmaceutical scientists, regulators, policymakers, and lawyers alike. This standalone, full-color resource broadly surveys innovative technologies and advances pertaining to nanomedicine and precision medicine. In addition, it addresses often-neglected yet crucial areas such as translational medicine, intellectual property law, ethics, policy, FDA regulatory issues, nano-nomenclature, and artificial nano-machines—all accomplished in a user-friendly, broad yet interconnected format. The book is essential reading for the novice and the expert alike in diverse fields such as medicine, law, pharmacy, genomics, biomedical sciences, ethics, and regulatory science. The book's multidisciplinary approach will attract a global audience and serve as a valuable reference resource for industry, academia, and government.

The enormous advances in nanomedicine and precision medicine in the past two decades necessitated this comprehensive reference, which can be relied upon by researchers, clinicians, pharmaceutical scientists, regulators, policymakers, and lawyers alike. This standalone, full-color resource broadly surveys innovative technologies and advances pertaining to nanomedicine and precision medicine. In addition, it addresses often-neglected yet crucial areas such as translational medicine, intellectual property law, ethics, policy, FDA regulatory issues, nano-nomenclature, and artificial nano-machines—all accomplished in a user-friendly, broad yet interconnected format. The book is essential reading for the novice and the expert alike in diverse fields such as medicine, law, pharmacy, genomics, biomedical sciences, ethics, and regulatory science. The book's multidisciplinary approach will attract a global audience and serve as a valuable reference resource for industry, academia, and government.

Biomedical Application of Nanoparticles explores nanoparticles, their chemical and physicals properties, and how they interact in biological systems with proteins, immune system and targeted cells. Risk assessment of nanoparticles for human is described, including: cellular paradigms, transcriptomics and toxicogenomics. Finally, the applications of nanoparticles in medicine and antioxidant regenerative therapeutics are presented in several chapters with emphasis on how nanoparticles enhance transport of drugs across biological membrane barriers and therefore may enhance drug bioavailability.

The editors of this book, who are world renown for their creativity with entomopathogenic nematodes, have assembled the foremost authorities from four continents to contribute on basic and applied concepts. The authors have taken advantage of this opportunity to express their views to a wide scientific audience. They have combined their international experience so that the latest developments in this fascinating and rapidly expanding field are present in comprehensive manner with diverse topics ranging from biological control theory to organismal and molecular biology.

In recent years, a tremendous amount of effort has been focused on better understanding the fundamentals of Alzheimer's disease (AD) to facilitate early and accurate diagnosis and appropriately targeted therapeutic treatments. Alzheimer's Disease: Targets for New Clinical, Diagnostic, and Therapeutic Strategies provides a detailed synopsis of the c

Astrocytes play diverse roles in central nervous system (CNS) function and dysfunction, and the connections that the astrocyte makes with other cells of the brain are essential for a variety of important neural tasks. Bringing together contributions from international experts at the top of their field, Astrocytes: Wiring the Brain emphasizes cellul

The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef

In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg

Micronutrients and Brain Health addresses cutting-edge research related to processes of oxidative stress that affect brain function, an area of increasing significance for those concerned and involved with public health and translational medicine. Edited by four leading micronutrient researchers, the book brings together the investigative work of m

Anemones and fish, ants and acacia trees, fungus and trees, buffaloes and oxpeckers--each of these unlikely duos is an inimitable partnership in which the species'coexistence is mutually beneficial. More specifically, they represent examples of defensive mutualism, when one species receives protection against predators or parasites in exchange for

At the nexus of advances in molecular genetics and findings in redox biology, this volume elaborates on the dynamics governing cellular redox states and aggregates the body of evidence linking oxidative stress and redox modulation with a host of monogenetic and polygenetic diseases.

Histochemistry deals with the activities of chemical components in cells, and immunohistochemistry addresses the function of cell types in tissue or organs, such as those leading to acceptance or rejection of grafts or organs. This book is a methods volume focusing on antigen retrieval, particularly methods used in disease-related antigens. Because the book is a methods volume and a lab manual, it will have an audience of pathologists, biochemists, and lab technicians.

The basic science of the cellular and molecular responses of the brain to injury is a rapidly expanding area of research that provides evidence of growing opportunities for pharmacological intervention in the clinic. CNS Injuries: Cellular Responses and Pharmacological Strategies is an examination of developments in our understanding of the cellular and trophic responses to CNS injuries and the potential treatment. This text collates reviews of the most important areas of study regarding injury response including inflammatory and immune reactions scarring neuron death demyelination and remyelination axonal regeneration re-establishment of neuronal connectivity Providing a record of recent advances that will help point the way to future developments, this enlightening reference is sure to benefit researchers and practitioners in a broad range of disciplines, including: neurology, pharmacology, pathology, toxicology, immunology, and many others.

This timely resource offers extensive discussions on the pharmacological, environmental,endocrinological, and natural factors that alter reproductive or developmental processes-elucidating the effects of toxicants on mechanisms of reproduction. Describing biological actions common to both genders as well as gender-specific processes, Reproducti