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Natural products are a marvel of evolution. Plants are chemical factories and have produced a vast number of highly diverse and interesting natural substances with their extraordinary properties, which we humans have been using for centuries to relieve and cure diseases. At the latest since the discovery of penicillin, natural substances have become an important source of medicines, but we know only very few of the presumably many millions that are still waiting to be discovered. Important antibiotics, immunosuppressants, anticancer agents, hormones, and antiviral agents are among the natural products. But do natural products still matter in the age of biotechnology and genetic engineering? Yes, more than ever, because medicinal chemists draw creative inspiration for their syntheses from nature to develop the next blockbuster in medicine. Oliver Kayser tells the story of natural products and medicinal plants in this book in a highly informative and amusing way from a new perspective. He explores how natural products from naturopathy gave birth to the pharmaceutical industry, how they shaped our society as medicines and remedies, enabled wars, and paved the way to Nobel Prizes. The author paints a fascinating panorama of natural product chemistry in plants, microorganisms, and animals. Starting with the first isolations at the beginning of the industrial revolution, he leads us with the ideas and enthusiasm of many scientists into the modern era of drug testing, computer chemistry, and the highly successful serendipitous discoveries of active ingredients. Natural product research in the laboratory has an enormous impact on our lives today. The author offers a glimpse over the shoulder of how the search for the new drugs of tomorrow works today. This book is the ultimate book from the pen of a scientist deeply rooted in research, providing the reader with an enlightening and at the same time entertaining insight into how scientists think and how arduous research can be.

This book conducts research on the evaluation and reduction mechanism of the negative effects of urban Transportation Energy Supply Network (TESN). By analyzing the current supply and demand situation of urban transportation energy supply network, the concept of negative effects of urban transportation energy supply network is defined, and specific definitions and measurement methods of negative effects are proposed. A TESN negative effect reduction mechanism was constructed from three aspects: site layout optimization, site cooperation game, and replenishment vehicle scheduling. The simulation validation of the urban transportation energy supply network was conducted using AnyLogic simulation software.

Scientific writing is a trade that can and must be learned and not a form of art that is limited to the talented. The real constraint for writing a good scientific article is most of the time not the usage of the English language, but the conversion of outcomes of a set of experiments into a coherent and convincing scientific story. This book is designed to guide junior scientists in the Life Sciences writing their thesis and first manuscripts, along this uphill struggle. All aspects of building up and publishing a forceful scientific narrative are covered, from designing experiments to dealing with the reviewers'comments. This book takes you step by step through the process of writing a paper. It starts by discussing how to collect and organize data and make an outline. The actual writing starts with the Results section, as this is the heart of any research paper. The Discussion interprets your data in the framework of the existing literature and explains the novel insights you obtained. The Introduction is written to pose the questions that are answered in the Discussion and give the necessary background information. It is written after the Results and Discussion to make sure it is a perfect match. The M&M is the easiest to write. A good abstract is essential for attracting readers. How to write that is described in detail. The title is the last piece of the puzzle. The book contains many practical examples that explain the general principles of good writing. These examples are all from the Life Sciences and so are the anecdotes that illustrate the concepts, making the information directly applicable. All kinds of tips and suggestions are provided for improving readability and accessibility of your manuscript, thus making it easier acceptable. In addition, background information on the basics of science is supplied that helps to avoid common mistakes that cause rejection of manuscripts that report on otherwise good science.

Industrial crops offer farmers new market opportunities to increase their revenue by producing high-value products, focusing on fiber, forest, and energy crops, industrial oilseeds, rubber and resins, pharmaceuticals, and more. Technological innovations in agriculture have facilitated higher yields, but conserving crop genetic resources and diversity remains crucial for sustainable agricultural production. This poses a challenge that can be addressed through modern tools of biotechnology and genomics, utilizing the wealth of sequenced plant genomes. This book addresses the need for knowledge in managing the risks and conservation of genetic diversity associated with advanced technology. It provides comprehensive coverage of plant genomics and biotechnology, catering to post-graduate students, researchers, employees of seed and biotechnology companies, as well as instructors in plant genetics, breeding, and biotechnology fields.

Antimicrobial peptides (AMPs) have been sought to be a potential alternative to the current arsenal of antibiotics against undesirable microbes. AMPs synthesized by lactic acid bacteria have attracted significant attention due to their strong activity against a broad range of bacteria including pathogens. The bacteriocin (an AMP) has been known to us since early 1928, a year before penicillin was reported. This is possibly due to their narrower activity compared to antibiotics. However, several AMPs having promising activity have been thoroughly characterized in the past few decades. Renewed interest has developed focusing on industrially important bacteriocins produced by lactic acid bacteria. Some of these AMPs are also active against food spoilage and clinically important pathogens. Similar to antibiotics, large-scale intellectual screening is ongoing in the search for novel AMPs with unique properties. Recent research has revealed that AMPs may also play a role in maintaining gut microflora and keeping us protected from food-borne pathogens. The ongoing genomic studies suggest that there may be more such bioactive compounds waiting to be explored. This book provides an overview of the fundamental knowledge accumulated so far regarding the diversity and potential applications of AMPs produced by lactic acid bacteria. This updated reference book on AMPs from lactic acid bacteria is timely, covering the most important achievements in the field and providing the scientific community particularly graduate students, researchers, and clinicians with the latest updates. The goal of this book is to illustrate and detail the findings made so far, debate the state of the art, and draw new perspectives.

The book explains the use of natural products as scaffolds in tissue engineering. It presents an introduction to the concept of natural product-based scaffolds and explores various fabrication strategies for their synthesis. The book highlights the wide range of applications of these scaffolds in tissue engineering, including their use in tissue regeneration, wound healing, plastic surgery, and breast reconstruction. Specific natural products, such as gums (xanthan, gellan, arabic, guar, ghatti gum), chitosan, collagen are discussed in separate chapters. In addition, various application of natural product loaded PCL and PLA scaffolds have also been discussed. Each chapter focuses on the application of these natural product based scaffolds and explores their potential in tissue engineering. It also covers specific applications of these scaffolds in tissue regeneration, including angiogenesis, bone, skin, and nerve tissue regeneration. The book addresses important considerations regarding the toxicity and regulatory aspects of natural product-based scaffolds and explores the challenges associated with their implementation and emphasizes the need for safety and compliance in their use. Overall, the book provides a comprehensive overview of the field. It serves as a valuable resource for researchers, scientists, and professionals in the field of tissue engineering.

This book provides insights into the recent developments in the field of bioprocess technology and bioreactor design. Bioprocess engineering or biochemical engineering is a subcomponent of chemical engineering, which encompasses designing and developing those processes and equipment that are required for the manufacturing of products from biological materials and sources, such as agriculture, pharmaceutical, chemicals, polymers, food, etc., or for the treatment of environmental process, for example, waste water. The main focus of this book is to highlight the advancements in the field of bioprocess technology and bioreactor design. The book is divided into various chapters briefing all aspects of bioprocess engineering and focusing on the advances in bioprocess engineering. The book summarizes introduction to bioprocess technology and microbiology, isolation and maintenance of microbial strains, and sterilization techniques for advanced-level students and researchers. Different models depicting kinetics of microbial growth, substrate consumption, and product formation are discussed. The applications of enzymes have increased tremendously and therefore understanding their metabolic pathways to increase yields is also briefly discussed. The calculations of mass and energy balances associated with entropy changes and free energy. This book also covers the approaches for handling different types of cell cultures and current advancements in the area of bioprocess strategies for different culture types, which scientists and researchers working in the different cell cultures can refer to. The downstream processing of various industrially important products is also a part of this book. Apart from that, the process economics which ensures the feasibility and quality of any biological process is also dealt with as the last section of the book.

Emergence of lifestyle diseases, e.g., type II diabetes, cancers, obesity, cardiovascular disorders, liver cirrhosis, etc., are exponentially increasing day by day. Modern drifts toward the utilization of herbal medicines in different healthcare aspects necessitate (demand) the replacement of synthetic molecules with phytoconstituents because of their biocompatibility, biodegradability, economic extraction process, and ready availability from the natural source. This book provides a thorough insight into the comprehensive and up-to-date trends of phytomedicines in the management of lifestyle diseases and its mechanisms, modern methods of extraction and purification of phytoconstituents, and chemical characterization as well as standardization of phytoconstituents using modern equipments.

This book provides technical information on different biological and hybrid wastewater treatment systems for treatment of wastewater and reuse. The contained information helps in tracking their progress of such systems toward practical and field-scale applications. The book also includes strategies to be adopted for minimizing the losses and maximizing the benefits. Additionally, it includes methods for protecting the environment through the application of advanced biological and hybrid wastewater treatment technology. Furthermore, it discusses the crucial parts that science, technology, and innovation play in the formulation, implementation, and administration of wastewater treatment policy. It highlights the challenges that must be overcome to adopt biological and hybrid wastewater treatment infrastructure regulations successfully and provides some answers. It investigates how the biological and hybrid wastewater treatment technology may be used in a wide variety of field's sets apart from other on-the-shelf publications on the market. Also, it delves into the core concepts of biological and hybrid wastewater treatment systems. It explores how these concepts can be modified to fit a variety of contexts and uses. Applications such as managing facilities, dealing with pandemics, urban wastewater treatment and reuse, farming, and other applications are included in this book. This book is helpful to researchers, entrepreneurs, professionals, planners, policymakers, environmental engineers, and others interested in biological and hybrid wastewater treatment system management strategies through the application of breakthroughs in biological and hybrid wastewater treatment technologies. Also, it is useful as a fundamental source of information and state-of-the-art knowledge to graduate students, university faculties, and researchers in the fields of environmental sciences/engineering, biological and chemical sciences, and NGO. It is also useful to entrepreneurs, professionals, and planners in policy and decision making at the local, state, and national levels for many countries.

The book introduces readers to the latest developments in biotechnological methods used for improving the cultivation of silkworms. The text focuses on implementing biotechnological approaches, ranging from basic to advanced techniques, on enhancing silk production, increasing abiotic stress resilience, improving disease tolerance, and developing resistance in silkworm crops. With the current climate crisis and growing demand for high-quality silk, biotechnological applications have become essential in addressing the urgent need to increase silk production. The field of sericulture has made significant breakthroughs, such as identifying DNA markers, linkage association, genome-wide association studies, generating mutants, and introducing transgenic silkworms. Developing silkworms with improved cocoon yield and disease resistance is crucial to boost silk production. The book covers fundamental principles and recent advancements and delves into various methodologies employed inseri-biotechnology for improving silkworm crops. These methodologies include next-generation sequencing for DNA sequencing, using molecular markers to enhance abiotic stress tolerance (specifically high temperature and humidity conditions), expression analysis, RNA interference, gene knockout approaches to bolster disease resistance, and transcriptomics to enhance economically significant parameters such as silk content. The book explains these topics in detail and includes contemporary research appraisals, extensive discussions, and an evaluation of the benefits and risks associated with the use of biotechnological tools. This book serves as an invaluable reference for researchers and academics in biotechnology, molecular biology, and sericulture while also serving as an informative starting point for budding researchers.

This book focuses on the various applications of microorganisms for sustainable environment and the reduction of hazardous pollutants released in various forms, including xenobiotics, e-waste, pesticides, insecticides, plastic, heavy metals, paper waste, medical waste, textile dyes, and their impact on environmental and human health. The book involves a series of research reports that explain the application of microbes used to solve real-life issues raised due to changes happening in environment, including pollution, by covering applications, including the use of bacteria, fungi, microalgae and biofilm in the detection and degradation of crude oil, pesticides, dyes, e-waste, heavy metals and other pollutants. It also focuses on integrative strategies in the application of microbial nanomaterials for remediation of pollutant. This material will help environmental scientists and microbiologists to learn about existing environmental problems and suggest novel ways to control or contain their effects by employing various treatment approaches.

Blockchain is a new type of technology that combines and secures information exchange between different stakeholders such as medical practitioners, patients, healthcare providers, and other applicable parties. Among them, Blockchain Technology is one of the most important areas in the bioinformatics application of biomedical research and healthcare systems utilizing unique requirements and integration features. All the chapters are written by experts and researchers working in various areas of the biomedical and healthcare domain and they also dive into one of the most overlooked methodological, practical, and moral questions to secure and handle the enormous amount of data being generated from IoT-enabled biomedical and healthcare systems. In the beginning, this book presents an overview and then discusses open issues, challenges, and applicability aspect of Blockchain technology in healthcare. Then, this book presents a variety of perspectives on the most pressing questions in the field, for example: how IoT can connect billions of biomedical and healthcare information; how the blockchain-based secure access control mechanisms in biomedical and healthcare work; how to address the Quality-of-Service (QoS) and real-time accessibility requirements for healthcare applications; and how to ensure communication with efficiency. Also, it discusses Blockchain for IoT-enabled healthcare systems and presents a comparative analysis with respect to various performance evaluation metrics too.

This book describes the basic concepts and recent advances in new discoveries and technologies related to microbial omics and their role in environmental research and human health. The term'omics'refers to a blend of high-throughput analysis and traditional methods including genomics, transcriptomics, proteomics, lipidomics and metabolomics for a variety of applications in the field of life sciences, biomedical sciences, environmental sciences, and related industries. The book aims to fill the existing gap in terms of a comprehensive approach that incorporates recent advances in this dynamic field and provides an answer to why this field requires an interdisciplinary research approach. The focus of this book is on the applications of genomics, epigenomics, metagenomics, integrative omics, machine learning and microbiome research in environmental health, disease, wastewater epidemiology, antibiotic resistance, drug discovery, cancer, production of secondary metabolites of microbial origin, oxidative stress alleviating mechanisms, etc. The overall construction of this book emphasizes three major perspectives, namely, elaborate knowledge from fundamentals to recent advances in technologies about omics in general and its application in microbiology, environment, and health in particular; illustrative figures capable of easy visualization of complex pathways; and serving as a platform for highly demanded bioinformatics strategies including relevant codes, programming scripts, machine learning and use of artificial intelligence strategies needed to streamline the research outcomes. With global contributions from authors from internationally renowned organizations who excel in relevant research, this book will benefit bibliophiles and prospective audiences from the research fraternity, academia, professionals, and experts in the field of life sciences, biomedical as well as industries related to the development of drug design and novel advances in biotechnological applications.

This book provides a comprehensive reference for various plant bioactive compounds for research and pharmacological significance across the entire spectrum of phytochemical genomics. The book opens with general information on diversity, analysis and genomic basis of phytochemicals, computational approaches, databases for responsible genes, and biosynthetic pathways, and it delves very much into the details behind phytochemical diversity and diverse roles of plant metabolites. The later parts of the book also explore the direct drug discovery and omics approaches including metabolomics, transcriptomics, as well as gene editing technology experiments to further inspire readers into its unlimited potentials. Each chapter includes detailed analysis and relevant experiments for better and deeper understanding of the concepts. The book will be an invaluable aid for medicinal plant researchers and a rich source of information and advice for advanced undergraduates and graduates in the fields of medicine, nutraceuticals, cosmetics, flavor, and fragrance studies.

Plant bioactive compounds are plant-based natural products that display a variety of pharmacological applications. These bioactive compounds are important as medicines, pigments and flavorings since most of the pharmaceutical industries are highly dependent on medicinal plants and their extraction. The types and concentrations of bioactive compounds produced by plants are determined by the species, genotype, physiology, developmental stage and environmental factors during growth, determining the physiological adaptive responses employed by various plant taxonomic groups in coping with the stress and defensive stimuli. In the past two decades there has been a renewed interest in the study of conventional aspects such as elicitors and biotic and abiotic stress factors that influence secondary metabolism during in vitro and in vivo growth of plants. the application of molecular biology tools and techniques are facilitating increased understanding of the signaling processes and pathwaysinvolved in the bioactive compounds production in subcellular, cellular, organ and whole plant systems during in vivo and in vitro growth, with application in the metabolic engineering of biosynthetic pathways intermediates. Biosynthesis and Manipulation of Bioactive compounds in Medicinal and Aromatic Plants provides a comprehensive introduction and review of the state-of-the-art biotechnological tools used in enhancement of bioactive compounds in medicinal and aromatic plants. Readers will find a systematic overview of techniques such as Omics, Crisper /Cas9 and RNAi to enhance plant bioactive contents including various in vitro techniques, hairy root culture and transgenic technology to enhance plant bioactive contents using plant tissue culture approaches. The chapters provide an overview of the role of induced mutation, biotic and abiotic stress to increase the bioactive contents in plants, plus the role of endophytes to enhance the contents of plant bioactive compounds and standard operating procedures using hydroponics system of cultivation for significant enhancement of bioactive compounds.This book serves as a single source for researchers working in plant secondary metabolites and the pharmaceutical industry.

This book provides a comprehensive introduction and review of state-of-the-art biotechnological tools in enhancement of bioactive compounds in medicinal and aromatic plants. Plant bioactive compounds are plant-based natural products that display a variety of pharmacological applications. These bioactive compounds are important as medicines, pigments, flavorings and drugs because most of the pharmaceutical industries are highly dependent on medicinal plants and their extraction. The book introduces a systematic overview of state-of-the-art biotechnological techniques such as Omics, Crisper /Cas9 and RNAi to enhance the plant bioactive contents as well as enlists various in vitro techniques, hairy root culture and transgenic technology to enhance plant bioactive contents using plant tissue culture approaches. The book also provides an overview of the role of induced mutation, biotic and abiotic stress to increase the bioactive contents in plants and discusses the significant role of endophytes to enhance the contents of plant bioactive compound. The book also opens discussions related to standard operating procedures using hydroponics system of cultivation for significant enhancement of bioactive compound(s) and much more. This book serves as an excellent reference book for the researchers working in the field of plant secondary metabolites and pharmaceutical industries at global level.

This book overviews purinergic receptors that are playing key roles in human and pathophysiological processes. The book elaborates on how selective P1 and P2 modulators have been developed as therapeutics for a variety of diseases. It also provides an overview of current perspectives in the design of purinergic receptor modulators and future challenges such as the availability of selective ligands for all receptor subtypes.Divided into 12 chapters, this comprehensive volume also offers a multidisciplinary perspective on the historical evolution, starting with a chapter devoted to the roots and early discoveries of adenosine and its receptors, followed by a twenty-year retrospective on the synthesis, properties, and functional potential of adenosine receptor ligands, probes, and functional conjugates. In the next chapters, experts in the field delve into topics such as the therapeutic potential of adenosine receptor ligands in wound healing and fibrosis, the therapeutic benefits of A2A receptor antagonists, the A2B adenosine receptor as a target for brain ischemia or demyelination, the development and latest advancements in clinical trials of A3 adenosine receptor ligands. Other chapters describe bifunctional tools to study adenosine receptors, allosteric modulators of adenosine receptors, and new computational approaches to inspect adenosine receptor-ligand recognition processes. Furthermore, the book discusses the role of P2X4 receptors in immunity and inflammation. The final chapters illustrate CD73 inhibitors as antitumor agents, and bacterial ectonucleotidases as underexplored antibacterial drug targets. This book is a valuable resource for scholars working in the field of medicinal chemistry, as well as researchers in the industry, providing readers with a comprehensive understanding of adenosine receptor biology and its therapeutic potential.

This book provides a meticulous view on methodological drug discovery and development insights from bench to bedside. The current book threads almost each step encompassing drug the discovery and development of a molecule. The chapters focus on computational modus operandi, pharmacological optimization approaches, modern high-throughput screening methods and in-vitro procedures, role of structural biologists in drug discovery and development, medicinal chemistry approaches for drug design, formulation and drug delivery, in-vivo evaluations of candidate molecules, clinical trial procedures and others. The book also covers specific case studies, regulatory approval proceedings, and industrial view point alongside the aforementioned conceptual layout. And at the same time, the volume integrates medical, biological, medicinal, pharmacological and computational streams, and it is suggested as an ideal guideline to a wide audience including molecular biologists, biochemist, pharmacologists, medicinal chemist, toxicologists, drug discovery and development researchers, and all other students interested in these disciplines.

This Major Reference Work offers a detailed overview of culturing primary, secondary cell lines, tissues, and organs.It first introduces various types of mammalian cell cultures, infrastructure requirements for a mammalian cell-culture laboratory. The subsequent chapters present the detailed protocols for the isolation of mammalian hematologic organs and cells. It also discusses various cell-based assays for monitoring cell viability, cell proliferation, cytotoxicity, cell senescence, and cell death assays.In addition, the book addresses the various problems encountered while culturing animal cells, their possible causes, and suggested solutions, presenting detailed protocols for isolation and primary culturing of various mammalian cells and hematoimmunologic organs in two dimensions.Lastly, it reviews the various applications of animal-cell culture, stem-cell culture, and tissue and organ culture. As such, this reference book is highly relevant for students and professionals new to cell-culture work as well as to those wishing to expand their skills from cell-line cultures to primary cultures and from conventional 2D cultures to 3D cultures.

For courses in general biology. The world's most successful majors biology text and media program are better than ever! The 11th Edition of the best-selling Campbell BIOLOGY sets students on the path to success in biology through its clear and engaging narrative, superior skills instruction, innovative use of art and photos, and fully integrated media resources to enhance teaching and learning. To engage learners in developing a deeper understanding of biology, the 11th Edition challenges them to apply their knowledge and skills to a variety of new hands-on activities and exercises in the text and online. Content updates throughout the text reflect rapidly evolving research, and new learning tools include Problem-Solving Exercises, Visualizing Figures, Visual Skills Questions, and more. MasteringBiology™ is not included. Students, if MasteringBiology is a recommended/mandatory component of the course, please ask your instructor for the correct ISBN. MasteringBiology should only be purchased when required by an instructor. Instructors, contact your Pearson representative for more information.MasteringBiology is an online homework, tutorial, and assessment program designed to work with this text to engage students and improve results. Interactive, self-paced tutorials provide individualized coaching to help students stay on track. With a wide range of activities available, students can actively learn, understand, and retain even the most difficult concepts.

For non-majors/mixed biology courses. Helping students understand why biology matters Campbell Essential Biology with Physiology makes biology interesting and understandable for non-majors biology students. This best-selling textbook, known for its scientific accuracy, clear explanations, and intuitive illustrations, has been revised to further emphasize the relevance of biology to everyday life, using memorable analogies, real-world examples, conversational language, engaging new Why Biology Matters photo essays, and more. MasteringBiology not included. Students, if MasteringBiology is a recommended/mandatory component of the course, please ask your instructor for the correct ISBN and course ID. MasteringBiology should only be purchased when required by an instructor. Instructors, contact your Pearson representative for more information. MasteringBiology is an online homework, tutorial, and assessment product that improves results by helping students quickly master concepts. Students benefit from self-paced tutorials that feature immediate wrong-answer feedback and hints that emulate the office-hour experience to help keep students on track. With a wide range of interactive, engaging, and assignable activities, many of them contributed by Essential Biology authors, students are encouraged to actively learn and retain tough course concepts. New MasteringBiology activities for this edition include “Essential Biology” videos that help students efficiently review key topics outside of class, “Evaluating Science in the Media” activities that help students to build science literacy skills, and “Scientific Thinking” coaching activities that guide students in understanding the scientific method.

Intended for non-majors or mixed biology courses. Soar to New Heights with Campbell Biology: Concepts & Connections! Campbell Biology: Concepts & Connections continues to introduce pedagogical innovations, which motivate students not only to learn, but also engage with biology. The Eighth Edition of this market-leading book builds on its hallmarks of accuracy, currency, and a dedication to revolutionizing teaching and learning solutions. This thorough revision focuses on providing instructors with the resources needed to invigorate the course and gives students the tools they need to succeed. This edition includes many new key figures to help students better visualize tough topics, while an increased emphasis on scientific thinking equips students to leave the course thinking like scientists. This program presents a teaching and learning experience—for you and your students. Engage in biology and make important connections between concepts and unifying themes: Immerse students in the world of biology, so they understand the connections across biological concepts. Focus on scientific thinking: Encourage students to think like scientists and develop scientific reasoning and literacy skills with new Scientific Thinking Modules and more. Maximize learning and success: Give students the tools they need to become skilled at learning and understanding course material.

Were you looking for the book with access to MasteringBiology? This product is the book alone, and does NOT come with access to MasteringBiology. Buy Biology; A Global Approach with MasteringBiology access card 10e (ISBN 9781292008752) if you need access to Mastering as well, and save money on this brilliant resource. This is a Pearson Global Edition. The Pearson Editorial team worked closely with educators around the world to include content especially relevant to students outside of the United States. The Tenth Edition of the best-selling text Campbell BIOLOGY helps launch students to success in biology through its clear and engaging narrative, superior pedagogy, and innovative use of art and photos to promote student learning. The Tenth Edition helps students develop a deeper understanding of biology by making connections visually across chapters and building the scientific skills needed for success in upper-level courses. New Make Connections Figures pull together content from different chapters visually, helping students see “big picture” relationships. New Scientific Skills Exercises in every chapter use real data to build key skills needed for biology, including data analysis, graphing, experimental design, and math skills. New examples show students how our ability to sequence DNA and proteins rapidly and inexpensively is transforming every subfield of biology.Mastering brings learning full circle and is the most effective and widely used online homework, tutorial, and assessment system for the sciences. Over three million science students are currently using Mastering for the following features: Before class, reading quizzes, pre-lecture quizzes, and formative assessments test students'knowledge of the material and ensure they come to class prepared. During class, Learning Catalytics and existing Mastering media like simulations, Flix, Videos, etc, keep your students engaged and bring tough topics to life. After class, “traditional” homework, quizzes, and testing automatically assess your students'comprehension of the material and provide opportunities for remediation.This product is the book alone, and does NOT come with access to Mastering. This title can be supported by Mastering, an online homework and tutorial system which can be fully integrated into an instructor's course. You can benefit from MasteringBiology at a reduced price by purchasing a pack containing a copy of the book and an access card for MasteringBiology: Biology, A Global Approach with MasteringBiology access card 10e (ISBN 9781292008752). Alternatively, buy access to Mastering and the eText – an online version of the book - online at www.masteringbiology.com. For educator access, contact your Pearson Account Manager. To find out who your Account Manager is, visit www.pearsoned.co.uk/replocator

As a component of post-genome science, the field of proteomics has assumed great prominence in recent years. Whereas quantitative analyses focussed initially on relative quantification, a greater emphasis is now placed on absolute quantification and consideration of proteome dynamics. Coverage of the topic of quantitative proteomics requires consideration both of the analytical fundamentals of quantitative mass spectrometry and the specific demands of the problem being addressed. Quantitative Proteomics aims to outline the state of the art in mass spectrometry-based quantitative proteomics, describing recent advances and current limitations in the instrumentation used, together with the various methods employed for generating high quality data. Details on both strategies describing how stable isotope labelling can be applied and methods for performing quantitative analysis of proteins in a label-free manner are given. The utility of these strategies to understanding cellular protein dynamics are then exemplified with chapters looking at spatial proteomics, dynamics of protein function as determined by quantifying changes in protein post-translational modification and protein turnover. Finally, a key application of these techniques to biomarker discovery and validation is presented, together with the rapidly developing area of quantitative analysis of protein-based foodstuffs. This exemplary book is essential reading for analytical and biological mass spectrometrists working in proteomics research, as well as those undertaking either fundamental or clinical-based investigations with an interest in understanding protein dynamics and/or biomarker assessment.

This book takes the reader on a journey of discovery through the biological world. It covers many important aspects of this vast subject, ranging from the biological molecules so vital for life, to whole populations of organisms and how they interact with

Personalise your teaching and create outstanding lessons with Dynamic Learning, the online subscription service that makes teaching and learning easier.If offers:- Time saving tools to streamline your planning - Outstanding content and lessons for your VLE- A simple way to integrate the trusted resources you've already createdWritten by experienced examiners and teachers, this is tailored precisely to the AQA Biology specification.- Personal Tutor presentations show students the key skills and techniques needed to pass their exams- Fully editable for structured tasks and project work- Extensive interactive quizzes to test and consolidate learning

While it is barely 50 years since the first reliable reports of the recovery of living cells frozen to cryogenic temperatures, there has been tremendous growth in the use of cryobiology in medicine, agriculture, horticulture, forestry, and the conservation of endangered or economically important species.As the first major text on cryobiolog

Biology Today is a truly innovative introductory biology text. Designed to combine the teaching of biological concepts within the context of current societal issues, Biology Today encourages introductory biology students to think critically about the role that science plays in their world. The Third Edition has been revised and updated, and contains three new chapters: Genetic Engineering and Genomics, New Infectious Threats, and Protecting the Biosphere.

In response to the popularity and critical acclaim of its other full-color science sets for students, Macmillan Reference USA has developed a comprehensive series of colorful, informative sets in the sciences. The Macmillan Science Library for Students will engage students at many levels -- from middle school and high school -- to nonmajors in college and lay readers in public libraries. This new series offers the most comprehensive views of key areas in the world of science. Each set explores all facets of the topic, offering not only descriptive and analytical information, but also cultural and ethical issues, and career opportunities in many fields of science.