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Human Evolutionary Genetics is a groundbreaking text which for the first time brings together molecular genetics and genomics to the study of the origins and movements of human populations. Starting with an overview of molecular genomics for the non-specialist (which can be a useful review for those with a more genetic background), the book shows h

How humanity brought about the climate crisis by departing from its evolutionary trajectory 15,000 years ago—and how we can use evolutionary principles to save ourselves from the worst outcomes.Despite efforts to sustain civilization, humanity faces existential threats from overpopulation, globalized trade and travel, urbanization, and global climate change. In A Darwinian Survival Guide, Daniel Brooks and Salvatore Agosta offer a novel—and hopeful—perspective on how to meet these tremendous challenges by changing the discourse from sustainability to survival. Darwinian evolution, the world's only theory of survival, is the means by which the biosphere has persisted and renewed itself following past environmental perturbations, and it has never failed, they explain. Even in the aftermath of mass extinctions, enough survivors remain with the potential to produce a new diversified biosphere.Drawing on their expertise as field biologists, Brooks and Agosta trace the evolutionary path from the early days of humans through the Late Pleistocene and the beginning of the Anthropocene all the way to the Great Acceleration of technological humanity around 1950, demonstrating how our creative capacities have allowed humanity to survive. However, constant conflict without resolution has made the Anthropocene not only unsustainable, but unsurvivable. Guided by the four laws of biotics, the authors explain how humanity should interact with the rest of the biosphere and with each other in accordance with Darwinian principles. They reveal a middle ground between apocalypse and utopia, with two options: alter our behavior now at great expense and extend civilization or fail to act and rebuild in accordance with those same principles. If we take the latter, then our immediate goal ought to focus on preserving as many of humanity's positive achievements—from high technology to high art—as possible to shorten the time needed to rebuild.

A sweeping account of male nurturing, explaining how and why men are biologically transformed when they care for babies It has long seemed self-evident that women care for babies and men do other things. Hasn't it always been so? When evolutionary science came along, it rubber-stamped this venerable division of labor: mammalian males evolved to compete for status and mates, while females were purpose-built to gestate, suckle, and otherwise nurture the victors'offspring. But come the twenty-first century, increasing numbers of men are tending babies, sometimes right from birth. How can this be happening? Puzzled and dazzled by the tender expertise of new fathers around the world—several in her own family—celebrated evolutionary anthropologist and primatologist Sarah Blaffer Hrdy set out to trace the deep history of male nurturing and explain a surprising departure from everything she had assumed to be “normal.”In Father Time, Hrdy draws on a wealth of research to argue that this ongoing transformation in men is not only cultural, but profoundly biological. Men in prolonged intimate contact with babies exhibit responses nearly identical to those in the bodies and brains of mothers. They develop caring potential few realized men possessed. In her quest to explain how men came to nurture babies, Hrdy travels back through millions of years of human, primate, and mammalian evolution, then back further still to the earliest vertebrates—all while taking into account recent economic and social trends and technological innovations and incorporating new findings from neuroscience, genetics, endocrinology, and more. The result is a masterful synthesis of evolutionary and historical perspectives that expands our understanding of what it means to be a man—and what the implications might be for society and our species.

Der international renommierte Biologe Lluís Quintana-Murci zeichnet in dieser so bahnbrechenden wie meisterhaften Darstellung die außergewöhnliche Geschichte der menschlichen Besiedlung auf der ganzen Welt nach. Er belegt die Existenz ausgestorbener Menschenarten und enthüllt, wie sich die menschlichen Populationen ständig untereinander, aber auch mit archaischen Menschen wie dem Neandertaler oder dem Denisova-Menschen vermischten. Ohne Vielfalt gibt es keine Evolution und keinen Fortschritt in irgendeinem Sinne des Wortes. Vor etwa sechzigtausend Jahren haben unsere Vorfahren Afrika verlassen, um sich über den gesamten Planeten zu verbreiten. Dies ist die erste große Migration in der Geschichte der Menschheit gewesen: Alle Menschen nicht-afrikanischer Herkunft sind Nachkommen dieser ersten «Migranten». Es war der Beginn einer langen Geschichte von Wanderungen, in deren Verlauf Europa, Asien und Australien vor etwa fünfzigtausend Jahren, Amerika vor weniger als dreißigtausend Jahren und viel später die Inseln des fernen Ozeaniens wurden. Die moderne Populationsgenetik ermöglicht uns, Wanderungsereignisse und andere demografische Prozesse zu datieren. Heute wissen wir, dass Vermischung ein kontinuierlicher Prozess im Laufe der Menschheitsgeschichte war und ist. Wir alle sind, in unterschiedlichem Maße, multiethnisch, da unsere Genome aus einer Vielzahl von DNA-Segmenten unterschiedlichster Herkunft bestehen – ein historischer und geografischer Flickenteppich, in dem sich Völker und Generationen vermischen.

This book serves as a gateway to the fascinating intersection of genetics, plant breeding and innovation, which is shaping the future of agriculture. It explores the dynamic world of molecular plant breeding, from decoding genetic markers to cutting-edge omics techniques. Each chapter is enriched with tables and diagrams for an engaging learning experience, simplifying complex concepts. The book begins with the basics, immersing you in molecular plant breeding, and then delves into genetic markers, diverse populations, linkage mapping, and association mapping. The book also covers such topics as marker-assisted selection, functional genomics, gene fingerprinting, gene transfer technologies, bioinformatics tools, and phenomics, and navigates the intricacies of intellectual property rights in molecular breeding.

The genome of a living being is composed of DNA sequences with diverse origins. Beyond single-copy genes, whose product has a biological function that can be inferred by experimentation, certain DNA sequences, present in a large number of copies, escape the most refined approaches aimed at elucidating their precise role. The existence of what 20th century geneticists had already perceived (and wrongly described as'junk DNA'!) was confirmed by the sequencing of the first complex genomes, including that of Homo sapiens. A large part of what defines a living thing is not unique, but repeated, sometimes a very large number of times, increasing in complexity with successive duplications and multiplication. Understanding and defining the many functions of this myriad of repeated sequences, as well as their evolution through natural selection, has become one of the major challenges for 21st century genomics.

The scientific study of human mating has mushroomed over the past three decades, and this growth in turn has generated a proliferation of evolving literature revealing fresh discoveries about mate attraction, mate choice, mate retention, marital satisfaction, jealousy, infidelity, intimate partner violence, breakups, internet dating, cyberstalking, and sexual coercion. In The Oxford Handbook of Human Mating, editor David M. Buss showcases contributions from'the best and the brightest'scientists in the field, providing up-to-date summaries of theories and empirical evidence of the science of human mating strategies. Much of the research in the field is guided by sexual selection theory. Over 150 years after Darwin's proposal of sexual selection theory, it has become the most important overarching theoretical framework for the scientific study of the mating strategies of all sexually reproducing species, including humans. A mountain of research centered around Darwin's classic book has documented the many complexities of human mate competition and mate choice; how these processes differ between the sexes; and how they differ as a function of sex ratio, mate value, social contexts, ovulation cycles, personality characteristics, and cultural norms and mating rituals. Thus, the science is now ripe for a collection of work by eminent scholars in the field. David M. Buss is a leading researcher and pioneer in the study of human mating strategies, and he applies his expertise to the curation of this volume, which includes major sections covering theories of human mating; mate selection and mate attraction; mate competition; sexual conflict in mating; human pair bonding; the endocrinology of mating; and mating in the modern world.

Contributors explore common elements in the evolutionary histories of both human and insect agriculture resulting from convergent evolution.During the past 12,000 years, agriculture originated in humans as many as twenty-three times, and during the past 65 million years, agriculture also originated in nonhuman animals at least twenty times and in insects at least fifteen times. It is much more likely that these independent origins represent similar solutions to the challenge of growing food than that they are due purely to chance. This volume seeks to identify common elements in the evolutionary histories of both human and insect agriculture that are the results of convergent evolution. The goal is to create a new, synthetic field that characterizes, quantifies, and empirically documents the evolutionary and ecological mechanisms that drive both human and nonhuman agriculture. The contributors report on the results of quantitative analyses comparing human and nonhuman agriculture; discuss evolutionary conflicts of interest between and among farmers and cultivars and how they interfere with efficiencies of agricultural symbiosis; describe in detail agriculture in termites, ambrosia beetles, and ants; and consider patterns of evolutionary convergence in different aspects of agriculture, comparing fungal parasites of ant agriculture with fungal parasites of human agriculture, analyzing the effects of agriculture on human anatomy, and tracing the similarities and differences between the evolution of agriculture in humans and in a single, relatively well-studied insect group, fungus-farming ants.

This book introduces cutting-edge studies on the spectrum of sex. The sex spectrum can be understood as an interwoven mechanism sustaining graded phenotypes between the two sexes. The book overviews three elements that develop the sex spectrum: genetics, the endocrine system, and the environment. Part I discusses the genetic regulation during sex determination, which often results in a mixture of two sexes or sex reversal. The evolutionary aspects of the genetic determinants are also discussed. Part II presents the involvement of endocrine regulation in the sex spectrum, which covers a broad range of phenotypic events, including sexual behavior and metabolism. Interestingly, sex hormones can also act as sex determinants. Finally, Part III shows that intrinsic factors, such as sex-determining genes and sex hormones, are not the only factors in sex development. The environment surrounding organisms, such as symbiosis and metabolism, act on the sex as critical factors, generating the sex spectrum. Determination and development of the two sexes have been a topic of great interest and a long-standing issue in biology. The book updates the conventional view that biological sex is fixed after birth and sets new perspectives for understanding sex as a spectrum manifested in multiple phenomena. Each chapter contributed by leading experts explains the sex spectrum in various organisms and their underlying mechanisms from the latest ongoing studies. The book provides a valuable resource for not only experts in developmental biology, physiology, and medical science, but also non-scientists and anyone interested in the topic.

DNA and RNA extraction methods from a variety of tissues and samples are now routine, including extraction from single cells. Many methods are now automated. Sequencing efficiency has reached the point where it is now possible to obtain gigabases of data, both quickly and inexpensively. Such methods permit the identification of gene versions, including those associated with disease (e.g. small nucleotide polymorphism analyses, or SNPs). The general public as well as clinicians can now access a wide variety of literature on the molecular bases of diseases, allowing them to better assess disease risks and treatments. This volume concentrates on medically-focused methods, and therefore the major audience will be medical professionals, students, and those involved in medically-related research endeavors. There are also papers in this volume dealing specifically with methods developed to analyze large sequence data sets. Many methods reviewed herein are more broadly applicable to other fields in biology, chemistry, bioinformatics, and bioengineering, and are intended for a broad readership.Key Features Summarizes nucleic acid extractions from a wide variety of tissues and cells Describes processes of nucleic acid preservation Reviews forensic sampling, detection of nucleic acids, and delivery of nucleic acids to multicellular organisms Provides essential guidance for sequencing, sequence analysis, database searches, and phylogenetic analyses Includes additional methods useful for analysis of nucleic acids and proteins Related TitlesDeSalle, et al. Phylogenomics: A Primer (ISBN 978-0-3670-2849-7).Jennings, W. B. Phylogenomic Data Acquisition: Principles and Practice (ISBN 978-0-3678-6980-9).Wang, X. Next-Generation Sequencing Data Analysis (ISBN 978-1-4822-1788-9)Sung, W.-K. Algorithms for Next-Generation Sequencing (ISBN 978-0-3676-5797-0)

This book explores important chapters of past and recent African history from a multidisciplinary perspective. It covers an extensive time range from the evolution of early humans to the complex cultural and genetic diversity of modern-day populations in Africa. Through a comprehensive list of chapters, the book focuses on different time-periods, geographic regions and cultural and biological aspects of human diversity across the continent. Each chapter summarises current knowledge with perspectives from a varied set of international researchers from diverse areas of expertise. The book provides a valuable resource for scholars interested in evolutionary history and human diversity in Africa. Contributors are Shaun Aron, Ananyo Choudhury, Bernard Clist, Cesar Fortes-Lima, Rosa Fregel, Jackson S. Kimambo, Faye Lander, Marlize Lombard, Fidelis T. Masao, Ezekia Mtetwa, Gilbert Pwiti, Michèle Ramsay, Thembi Russell, Carina Schlebusch, Dhriti Sengupta, Plan Shenjere-Nyabezi, Mário Vicente.

This is an introductory textbook for the study of human evolution, and covers all major topics of human origins taught under paleoanthropology, anthropology, archaeology, and evolutionary biology courses. This book differs from the existing selection of textbooks in the following ways:•It incorporates the most recent fossil discoveries and interpretations.•It balances the discussion between descriptions of fossils and interpretations of behavior of hominins in different time periods. •It includes current findings of genomics into understanding the more recent stages of human evolution. This important subdiscipline is badly underserved by current texts.•It consistently addresses the relationship of evidence to our current hypotheses and interpretations.The book has an engaging and lucid style suitable for those entering the field. Students will find ample case studies, illustrations and examples helpful in understanding difficult concepts. Tables, timelines, and maps in every chapter include data summaries and key points. The book highlights peripheral points and background concepts in side boxes for easy reference and lists key ideas at the end of each chapter. This up-to-date and easy to read text is suitable for both classroom study and self-learning.

This two-volume edited book highlights and reviews the potential of the fossil record to calibrate the origin and evolution of parasitism, and the techniques to understand the development of parasite-host associations and their relationships with environmental and ecological changes. The book deploys a broad and comprehensive approach, aimed at understanding the origins and developments of various parasite groups, in order to provide a wider evolutionary picture of parasitism as part of biodiversity. This is in contrast to most contributions by parasitologists in the literature that focus on circular lines of evidence, such as extrapolating from current host associations or distributions, to estimate constraints on the timing of the origin and evolution of various parasite groups. This approach is narrow and fails to provide the wider evolutionary picture of parasitism on, and as part of, biodiversity.Volume two focuses on the importance of direct host associations and hostresponses such as pathologies in the geological record to constrain the role of antagonistic interactions in driving the diversification and extinction of parasite-host relationships and disease. To better understand the impact on host populations, emphasis is given to arthropods, colonial metazoans, echinoderms, mollusks and vertebrates as hosts. In addition, novel techniques used to constrain interactions in deep time are discussed ranging from chemical and microscopic investigations of host remains, such as blood and coprolites, to the statistical inference of lateral transfer of transposons and host-parasite coevolutionary dynamics using molecular divergence time estimation.

Evolution is the single unifying principle of biology and core to everything in the life sciences. More than a century of work by scientists from across the biological spectrum has produced a detailed history of life across the phyla and explained the mechanisms by which new species form.This textbook covers both this history and the mechanisms of speciation; it also aims to provide students with the background needed to read the research literature on evolution. Students will therefore learn about cladistics, molecular phylogenies, the molecular-genetical basis of evolutionary change including the important role of protein networks, symbionts and holobionts, together with the core principles of developmental biology. The book also includes introductory appendices that provide background knowledge on, for example, the diversity of life today, fossils, the geology of Earth and the history of evolutionary thought.Key Features Summarizes the origins of life and the evolution of the eukaryotic cell and of Urbilateria, the last common ancestor of invertebrates and vertebrates. Reviews the history of life across the phyla based on the fossil record and computational phylogenetics. Explains evo-devo and the generation of anatomical novelties. Illustrates the roles of small populations, genetic drift, mutation and selection in speciation. Documents human evolution using the fossil record and evidence of dispersal across the world leading to the emergence of modern humans.

It's time for a story of human evolution that goes beyond describing'ape-men'and talks about what women and children were doing. In a few decades, a torrent of new evidence and ideas about human evolution has allowed scientists to piece together a more detailed understanding of what went on thousands and even millions of years ago. We now know much more about the problems our ancestors faced, the solutions they found, and the trade-offs they made. The drama of their experiences led to the humans we are today: an animal that relies on a complex culture. We are a species that can — and does — rapidly evolve cultural solutions as we face new problems, but the intricacies of our cultures mean that this often creates new challenges. Our species'unique capacity for culture began to evolve millions of years ago, but it only really took off in the last few hundred thousand years. This capacity allowed our ancestors to survive and raise their difficult children during times of extreme climate chaos. Understanding how this has evolved can help us understand the cultural change and diversity that we experience today. Lesley Newson and Peter Richerson, a husband-and-wife team based at the University of California, Davis, began their careers with training in biology. The two have spent years — together and individually — researching and collaborating with scholars from a wide range of disciplines to produce a deep history of humankind. In A Story of Us, they present this rich narrative and explain how the evolution of our genes relates to the evolution of our cultures. Newson and Richerson take readers through seven stages of human evolution, beginning seven million years ago with the apes that were the ancestors of humans and today's chimps and bonobos. The story ends in the present day and offers a glimpse into the future.

Does the field of evolution differ from other sciences? The author, a reviewer for a major medical journal, scrutinized hundreds of scientific references in evolutionary literature, adopting the same standards used for studies submitted for medical public

Many complex traits define the primate condition, including behaviors as fundamental as locomotion and traits as scrutinized as the dentition, and their study reveals dramatic evolutionary change across the primates. Genetic modifications are at the basis of these changes, but transformation of genetic information into phenotypes occurs at the level of the cell, which is the focus of this book. Contributors summarize novel methodologies to analyze the collective behavior of cells in forming tissues and organs influencing physiological functions and anatomical features that enable behaviors. Our goal is to review current knowledge and encourage others to adopt evolutionary cell biology to aid in deciphering the genotype-phenotype map that underlies the diversification of primates, human variation, and human evolution. The contributors to this book utilize advances in genetic analysis and visualization of cells and tissues and merge evolutionary developmental biology with evolutionary cell biology to address questions central to understanding human and primate evolution.Key Features Explores mechanisms underlying trait development, distribution, variation, and evolution, especially with respect to pigmentation, dental formulae, the skeleton, energetics, and temperature-related morphological variation Documents the advantages for anthropologists to work at the level of cells, focusing on how genes provide instructions for cells to make structure and how environment affects the behavior of cells Illustrates the role cell biology plays in pelage growth and pigmentation, facial morphology, melanin production in pigmentation, dental development and tooth loss, and energy expenditure Describes novel methodologies and techniques to analyze environment- and temperature-related influences on phenotypes Demonstrates how significant changes in life history occur at the level of the cell Related TitlesBianchi, L. Developmental Neurobiology (ISBN 978-0-8153-4482-7)King, G. R. Primate Behavior and Human Origins (ISBN 978-1-138-85317-1)Rhys Evans, P. H. The Waterside Ape: An Alternate Account of Human Evolution (ISBN 978-0-367-14548-4)

This two-volume set provides a general overview of the evolution of the human genome; The first volume overviews the human genome with descriptions of important gene groups. This second volume provides up-to-date, concise yet ample knowledge on the genome evolution of modern humans. It comprises twelve chapters divided into two parts discussing “Non-neutral Evolution on Human Genes” (Part I) and “Evolution of Modern Human Populations” (Part II.) The most significant feature of this book is the continent-wise discussion of modern human dispersal using human genomic data in Part II. Recent results such as introgression of paleogenomes to modern humans, new methods such as computer simulation of global human dispersals, and new information on genes for humanness will be of particular interest to the readers. Since the euchromatin regions of the human genome was sequenced in 2003, a huge number of research papers were published on modern human evolution for a variety ofpopulations. It is now time to summarize these achievements. This book stands out as the most comprehensive book on the modern human evolution, focusing on genomic points of view with a broad scope. Primary target audiences are researchers and graduate students in evolutionary biology.

This book includes 16 selected contributions presented at the 23rd Evolutionary Biology Meeting, which took place in Marseille in September 2019. The annual Evolutionary Biology Meetings in Marseille serve to gather leading evolutionary biologists and other scientists using evolutionary biology concepts, e.g. for medical research. The aim of these meetings is to promote the exchange of ideas to encourage interdisciplinary collaborations. Offering an up-to-date overview of recent findings in the field of evolutionary biology, this book is an invaluable source of information for scientists, teachers and advanced students.

The Arctic is a special world. The Arctic Ocean is covered by white sea ice, and its margins are surrounded by bare terrestrial regions, known as tundra. Tundra is a cold and dry environment without trees, but even in the absence of trees, tundra plants such as dwarf shrubs, grasses, herbs and moss support the harsh environment by providing sustenance and shelter. This book introduces representative arctic plants and their function in Svalbard, revealing the unique tundra ecosystem, and discussing the direct and indirect effects of climate change in the Arctic.

Advances in genome-scale DNA sequencing technologies have revolutionized genetic research on ancient organisms, extinct species, and past environments. When it is recoverable after hundreds or thousands of years of unintended preservation, “ancient DNA” (or aDNA) is often highly degraded, necessitating specialized handling and analytical approaches. Paleogenomics defines the field of reconstructing and analyzing the genomes of historic or long-dead organisms, most often through comparison with modern representatives of the same or similar species. The opportunity to isolate and study paleogenomes has radically transformed many fields, spanning biology, anthropology, agriculture, and medicine. Examples include understanding evolutionary relationships of extinct species known only from fossils, the domestication of plants and animals, and the evolution and geographical spread of certain pathogens. This pioneering book presents a snapshot view of the history, current status, and future prospects of paleogenomics, taking a broad viewpoint that covers a range of topics and organisms to provide an up-to-date status of the applications, challenges, and promise of the field. This book is intended for a variety of readerships, including upper-level undergraduate and graduate students, professionals and experts in the field, as well as anyone excited by the extraordinary insights that paleogenomics offers.

The vertebral spine is a key element of the human anatomy. Its main role is to protect the spinal cord and the main blood vessels. The axial skeleton, with its muscles and joints, provides stability for the attachment of the head, tail and limbs and, at the same time, enables the mobility required for breathing and for locomotion. Despite its great importance, the vertebral spine is often over looked by researchers because: a) vertebrae are fragile in nature, which makes their fossilization a rare event; b) they are metameric (seriated and repeated elements) that make their anatomical determination and, thus, their subsequent study difficult; and c) the plethora of bones and joints involved in every movement or function of the axial skeleton makes the reconstruction of posture, breathing mechanics and locomotion extremely difficult. It is well established that the spine has changed dramatically during human evolution. Spinal curvatures, spinal load transmission, and thoracic shape of bipedal humans are derived among hominoids. Yet, there are many debates as to how and when these changes occurred and to their phylogenetic, functional, and pathological implications. In recent years, renewed interest arose in the axial skeleton. New and exciting finds, mostly from Europe and Africa, as well as new methods for reconstructing the spine, have been introduced to the research community. New methodologies such as Finite Element Analysis, trabecular bone analysis, Geometric Morphometric analysis, and gait analysis have been applied to the spines of primates and humans. These provide a new and refreshing look into the evolution of the spine. Advanced biomechanical research regarding posture, range of motion, stability, and attenuation of the human spine has interesting evolutionary implications. Until now, no book that summarizes the updated research and knowledge regarding spinal evolution in hominoids has been available. The present book explores both these new methodologies and new data, including recent fossil, morphological, biomechanical, and theoretical advances regarding vertebral column evolution. In order to cover all of that data, we divide the book into four parts: 1) the spine of hominoids; 2) the vertebral spine of extinct hominins; 3) ontogeny, biomechanics and pathology of the human spine; and 4) new methodologies of spinal research. These parts complement each other and provide a wide and comprehensive examination of spinal evolution.

Evolutionary science teaches that humans arose as a population, sharing common ancestors with other animals. Most readers of the book of Genesis in the past understood all humans descended from Adam and Eve, a couple specially created by God. These two teachings seem contradictory, but is that necessarily so? In the fractured conversation of human origins, can new insight guide us to solid ground in both science and theology?In The Genealogical Adam and Eve, S. Joshua Swamidass tests a scientific hypothesis: What if the traditional account is somehow true, with the origins of Adam and Eve taking place alongside evolution? Building on well-established but overlooked science, Swamidass explains how it's possible for Adam and Eve to be rightly identified as the ancestors of everyone. His analysis opens up new possibilities for understanding Adam and Eve, consistent both with current scientific consensus and with traditional readings of Scripture. These new possibilities open a conversation about what it means to be human.In this book, Swamidassuntangles several misunderstandings about the words human and ancestry, in both science and theologyexplains how genetic and genealogical ancestry are different, and how universal genealogical ancestry creates a new opportunity for rapprochementexplores implications of genealogical ancestry for the theology of the image of God, the fall, and people'outside the garden'Some think Adam and Eve are a myth. Some think evolution is a myth. Either way, the best available science opens up space to engage larger questions together. In this bold exploration, Swamidass charts a new way forward for peace between mainstream science and the Christian faith.

Ancestral DNA, Human Origins, and Migrations describes the genesis of humans in Africa and the subsequent story of how our species migrated to every corner of the globe. Different phases of this journey are presented in an integrative format with information from a number of disciplines, including population genetics, evolution, anthropology, archaeology, climatology, linguistics, art, music, folklore and history. This unique approach weaves a story that has synergistic impact in the clarity and level of understanding that will appeal to those researching, studying, and interested in population genetics, evolutionary biology, human migrations, and the beginnings of our species. - Integrates research and information from the fields of genetics, evolution, anthropology, archaeology, climatology, linguistics, art, music, folklore and history, among others - Presents the content in an entertaining and synergistic style to facilitate a deep understanding of human population genetics - Informs on the origins and recent evolution of our species in an approachable manner

A tale of cave bears and comet strikes and a hundred million years of history by the bestselling author of Here on Earth: “Marvelous.”—Publishers Weekly (starred review) In Europe: A Natural History, world-renowned scientist, explorer, and conservationist Tim Flannery applies the eloquent interdisciplinary approach he used in his ecological histories of Australia and North America to the story of Europe. He begins 100 million years ago, when the continents of Asia, North America, and Africa interacted to create an island archipelago that would later become the Europe we know today. It was on these ancient tropical lands that the first distinctly European organisms evolved. Flannery teaches us about Europe's midwife toad, which has endured since the continent's beginning, while elephants, crocodiles, and giant sharks have come and gone. He explores the monumental changes wrought by the devastating comet strike and shows how rapid atmospheric shifts transformed the European archipelago into a single landmass during the Eocene. As the story moves through millions of years of evolutionary history, Flannery eventually turns to our own species, describing the immense impact humans had on the continent's flora and fauna—within 30,000 years of our arrival in Europe, the woolly rhino, the cave bear, and the giant elk, among others, would disappear completely. The story continues right up to the present, as Flannery describes Europe's leading role in wildlife restoration, and then looks ahead to ponder the continent's future: with advancements in gene editing technology, European scientists are working to recreate some of the continent's lost creatures, such as the great ox of Europe's primeval forests and even the woolly mammoth.

Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics, genomics and cell biology.Maintaining the features that have made previous editions so popular, this fifth edition has been completely updated in line with the latest developments in the field. Older technologies such as cloning and hybridization have been merged and summarized, coverage of newer DNA sequencing technologies has been expanded, and powerful new gene editing and single-cell genomics technologies have been added. The coverage of GWAS, functional genomics, stem cells, and disease modeling has been expanded. Greater focus is given to inheritance and variation in the context of populations and on the role of epigenetics in gene regulation. Key features: Fully integrated approach to the molecular aspects of human genetics, genomics, and cell biology Accessible text is supported and enhanced throughout by superb artwork illustrating the key concepts and mechanisms Summary boxes at the end of each chapter provide clear learning points Annotated further reading helps readers navigate the wealth of additional information in this complex subject and provides direction for further study Reorganized into five sections for improved access to related topics Also new to this edition – brand new chapter on evolution and anthropology from the authors of the highly acclaimed Human Evolutionary Genetics A proven and popular textbook for upper-level undergraduates and graduate students, the new edition of Human Molecular Genetics remains the ‘go-to'book for those studying human molecular genetics or genomics courses around the world.

A groundbreaking book about how ancient DNA has profoundly changed our understanding of human history. Geneticists like David Reich have made astounding advances in the field of genomics, which is proving to be as important as archeology, linguistics, and written records as a means to understand our ancestry. In Who We Are and How We Got Here, Reich allows readers to discover how the human genome provides not only all the information a human embryo needs to develop but also the hidden story of our species. Reich delves into how the genomic revolution is transforming our understanding of modern humans and how DNA studies reveal deep inequalities among different populations, between the sexes, and among individuals. Provocatively, Reich's book suggests that there might very well be biological differences among human populations but that these differences are unlikely to conform to common stereotypes. Drawing upon revolutionary findings and unparalleled scientific studies, Who We Are and How We Got Here is a captivating glimpse into humankind—where we came from and what that says about our lives today.

This book presents 19 selected contributions to the 20th Evolutionary Biology Meeting in Marseille, which took place in September 2016. They are grouped under the following major themes:· Self/Nonself Evolution· Species Evolution and Evolution of Complex Traits· Methods and Concepts The aims of the annual meetings in Marseille – which bring together leading evolutionary biologists and other scientists using evolutionary biology concepts, e.g. for medical research – are to promote the exchange of ideas and to encourage interdisciplinary collaborations. Offering a revealing overview of the latest findings in the field of evolutionary biology, this book represents an invaluable source of information for scientists, teachers and advanced students alike.

Biodiversity—the genetic variety of life—is an exuberant product of the evolutionary past, a vast human-supportive resource (aesthetic, intellectual, and material) of the present, and a rich legacy to cherish and preserve for the future. Two urgent challenges, and opportunities, for 21st-century science are to gain deeper insights into the evolutionary processes that foster biotic diversity, and to translate that understanding into workable solutions for the regional and global crises that biodiversity currently faces. A grasp of evolutionary principles and processes is important in other societal arenas as well, such as education, medicine, sociology, and other applied fields including agriculture, pharmacology, and biotechnology. The ramifications of evolutionary thought also extend into learned realms traditionally reserved for philosophy and religion. The central goal of the In the Light of Evolution (ILE) series is to promote the evolutionary sciences through state-of-the-art colloquia—in the series of Arthur M. Sackler colloquia sponsored by the National Academy of Sciences—and their published proceedings. Each installment explores evolutionary perspectives on a particular biological topic that is scientifically intriguing but also has special relevance to contemporary societal issues or challenges. This tenth and final edition of the In the Light of Evolution series focuses on recent developments in phylogeographic research and their relevance to past accomplishments and future research directions.

This book reviews the human genome from an evolutionary perspective. No such book has ever been published before, although there are many books on human genomes. There are two parts in this book: Overview of the Human Genome (Part I) and The Human Genome Viewed through Genes (Part II). In Part I, after a brief review of human evolution and the human genome (by Naruya Saitou), chapters on rubbish or junk DNA (by Dan Graur), GC content heterogeneity (by Satoshi Oota), protein coding and RNA coding genes (by Tadashi Imanishi), duplicated genes (by Takashi Kitano), recombinations (by Montanucci and Bertranpetit), and copy number variations including microsatellites (by Naoko Takezaki) are discussed. Readers can obtain various new insights on the human genome from this part. In Part II, genes in X and Y chromosomes (by Yoko Satta and others), HLA genes (by Timothy A. Jinam), opsin genes (by Shoji Kawamura and Amanda D. Melin), genes related to phenotypic variations (by RyosukeKimura), transcription factors (by Mahoko Takahashi and So Nakagawa), diabetes-related genes (by Ituro Inoue), disease genes in general (by Ituro Inoue and Hirofumi Nakaoka), and microbial genomes (by Chaochun Wei) are discussed. The human genome sequences were determined in 2004, and after more than 10 years we are now beginning to understand the human genome from an evolutionary point of view. This book furnishes readers with a good summary of current research in the field.

Knowledge of chimpanzees in the wild has expanded dramatically in recent years. This comprehensive volume, edited by Martin Muller, Richard Wrangham, and David Pilbeam, brings together scientists who are leading a revolution to discover and explain what is unique about humans, by studying their closest living relatives. Their observations and conclusions have the potential to transform our understanding of human evolution.Chimpanzees offer scientists an unmatched view of what distinguishes humanity from its apelike ancestors. Based on evidence from the hominin fossil record and extensive morphological, developmental, and genetic data, Chimpanzees and Human Evolution makes the case that the last common ancestor of chimpanzees and humans was chimpanzee-like. It most likely lived in African rainforests around eight million years ago, eating fruit and walking on its knuckles. Readers will learn why chimpanzees are a better model for the last common ancestor than bonobos, gorillas, or orangutans. A thorough chapter-by-chapter analysis reveals which key traits we share with chimpanzees and which appear to be distinctive to Homo sapiens, and shows how understanding chimpanzees helps us account for the evolution of human uniqueness. Traits surveyed include social behaviors and structures, mating systems, diet, hunting practices, tool use, culture, cognition, and communication.Edited by three of primatology's most renowned experts, with contributions from 32 scholars drawing on decades of field research, Chimpanzees and Human Evolution provides readers with detailed up-to-date information on what we can infer about our chimpanzee-like ancestors and points the way forward for the next generation of discoveries.

Modern Humans is a vivid account of the most recent—and perhaps the most important—phase of human evolution: the appearance of anatomically modern people (Homo sapiens) in Africa less than half a million years ago and their later spread throughout the world. Leaving no stone unturned, John F. Hoffecker demonstrates that Homo sapiens represents a “major transition” in the evolution of living systems in terms of fundamental changes in the role of non-genetic information. Modern Humans synthesizes recent findings from genetics (including the rapidly growing body of ancient DNA), the human fossil record, and archaeology relating to the African origin and global dispersal of anatomically modern people. Hoffecker places humans in the broad context of the evolution of life, emphasizing the critical role of genetic and non-genetic forms of information in living systems as well as how changes in the storage, transmission, and translation of information underlie major transitions in evolution. He also draws on information and complexity theory to explain the emergence of Homo sapiens in Africa several hundred thousand years ago and the rapid and unprecedented spread of our species into a variety of environments in Australia and Eurasia, including the Arctic and Beringia, beginning between 75,000 and 60,000 years ago. This magisterial work will appeal to all with an interest in the ever-fascinating field of human evolution.

Our experience of the world is driven by processes common to all animals: growth, survival, reproduction and death. Evolution and Human Behaviour explores the complexities of the human experience through the lens of Darwinism, drawing on a long and vibrant tradition of different theories and interpretations. This textbook offers a compelling synthesis of key concepts, addressing human thought, feeling and behaviour in fundamental evolutionary terms. This is a essential text for undergraduate students taking courses in psychology, human biology, ethology, anthropology and human behavioural ecology, providing an insightful and comprehensive introduction for anyone who wishes to understand how human behaviour has evolved.New to this Edition:- Additional chapters on health and disease, homosexuality, the nature of adaptations and life history theory.- Includes brand-new material on epigenetics, patterns of crime, error management theory, moral foundations theory, religion and gene culture co-evolution.- Now accompanied by a companion website offering additional reading material and useful practice questions- New'controversy'boxes in each chapter, providing ideas for essay topics and classroom discussion

Contributors from a range of disciplines consider the disconnect between human evolutionary studies and the rest of evolutionary biology.The study of human evolution often seems to rely on scenarios and received wisdom rather than theory and methodology, with each new fossil or molecular analysis interpreted as supporting evidence for the presumed lineage of human ancestry. We might wonder why we should pursue new inquiries if we already know the story. Is paleoanthropology an evolutionary science? Are analyses of human evolution biological? In this volume, contributors from disciplines that range from paleoanthropology to philosophy of science consider the disconnect between human evolutionary studies and the rest of evolutionary biology. All of the contributors reflect on their own research and its disciplinary context, considering how their fields of inquiry can move forward in new ways. The goal is to encourage a more multifaceted intellectual environment for the understanding of human evolution.Topics discussed include paleoanthropology's history of procedural idiosyncrasies; the role of mind and society in our evolutionary past; humans as large mammals rather than a special case; genomic analyses; computational approaches to phylogenetic reconstruction; descriptive morphology versus morphometrics; and integrating insights from archaeology into the interpretation of human fossils.ContributorsMarkus Bastir, Fred L. Bookstein, Claudine Cohen, Richard G. Delisle, Robin Dennell, Rob DeSalle, John de Vos, Emma M. Finestone, Huw S. Groucutt, Gabriele A. Macho, Fabrizzio Mc Manus, Apurva Narechania, Michael D. Petraglia, Thomas W. Plummer, J.W. F. Reumer, Jeff Rosenfeld, Jeffrey H. Schwartz, Dietrich Stout, Ian Tattersall, Alan R. Templeton, Michael Tessler, Peter J. Waddell, Martine Zilversmit

Noam Chomsky and Robert Berwick draw on recent developments in linguistic theory to offer an evolutionary account of language and our remarkable, species-specific ability to acquire it.“A loosely connected collection of four essays that will fascinate anyone interested in the extraordinary phenomenon of language.”—New York Review of BooksWe are born crying, but those cries signal the first stirring of language. Within a year or so, infants master the sound system of their language; a few years after that, they are engaging in conversations. This remarkable, species-specific ability to acquire any human language—“the language faculty”—raises important biological questions about language, including how it has evolved. This book by two distinguished scholars—a computer scientist and a linguist—addresses the enduring question of the evolution of language.Robert Berwick and Noam Chomsky explain that until recently the evolutionary question could not be properly posed, because we did not have a clear idea of how to define “language” and therefore what it was that had evolved. But since the Minimalist Program, developed by Chomsky and others, we know the key ingredients of language and can put together an account of the evolution of human language and what distinguishes us from all other animals.Berwick and Chomsky discuss the biolinguistic perspective on language, which views language as a particular object of the biological world; the computational efficiency of language as a system of thought and understanding; the tension between Darwin's idea of gradual change and our contemporary understanding about evolutionary change and language; and evidence from nonhuman animals, in particular vocal learning in songbirds.

Basics in Human Evolution offers a broad view of evolutionary biology and medicine. The book is written for a non-expert audience, providing accessible and convenient content that will appeal to numerous readers across the interdisciplinary field. From evolutionary theory, to cultural evolution, this book fills gaps in the readers'knowledge from various backgrounds and introduces them to thought leaders in human evolution research. - Offers comprehensive coverage of the wide ranging field of human evolution - Written for a non-expert audience, providing accessible and convenient content that will appeal to numerous readers across the interdisciplinary field - Provides expertise from leading minds in the field - Allows the reader the ability to gain exposure to various topics in one publication

In this changing world of what is socially and politically'correct,'polygamy is perhaps the last great taboo. Over the last thousand years, monogamy - at least in name - has been the default setting for coupledom and procreation in the Western world. And yet, throughout history, there have been inklings that'one-man, one-woman'is an uncomfortable institution for human beings. The consistently high rate of marital'cheating'by both sexes, plus the persistent interest in a variety of sexual partners - on the part of women as well as men - suggest strongly that monogamy isn't easy, and certainly isn't'natural,'for either sex. Esteemed writer and evolutionary biologist David P. Barash tackles this uncomfortable finding: that humans are actually biologically and anthropologically inclined toward polygamy. Drawing on decades of research, Barash presents a remarkable array of scientific evidence from evolutionary biology and cross-cultural studies that guide the reader through the hidden impacts of polygamy on such crucial behavior as violence, parenting, sexual preferences, adultery and efforts at monogamy itself, along with mind-bending speculation about the possible role of our polygamous predisposition when it comes to human genius, homosexuality and even monotheism. But take heart, monogamists! Although our species has long been'out of Eden,'this fascinating read is ultimately reassuring that'biology is not destiny.'

Are humans still subject to the forces of evolution? An evolutionary biologist provides surprising insights into the future of Homo sapiens In this intriguing book, evolutionary biologist Scott Solomon draws on the explosion of discoveries in recent years to examine the future evolution of our species. Combining knowledge of our past with current trends, Solomon offers convincing evidence that evolutionary forces still affect us today. But how will modernization—including longer lifespans, changing diets, global travel, and widespread use of medicine and contraceptives—affect our evolutionary future? Solomon presents an entertaining and accessible review of the latest research on human evolution in modern times, drawing on fields from genomics to medicine and the study of our microbiome. Surprising insights, on topics ranging from the rise of online dating and Cesarean sections to the spread of diseases such as HIV and Ebola, suggest that we are entering a new phase in human evolutionary history—one that makes the future less predictable and more interesting than ever before.

Estas Crónicas de la extinción relatan la extinción de diversas especies animales. Comienzan con la historia de las tortugas de las islas Galápagos, y continúan en los episodios II y III con el recuento histórico de la manera en que la ciencia comprobó a través del registro fósil la extinción de las especies. La llamada extinción de los dinosaurios se detalla en el episodio IV; mientras que los capítulos V y VI narran las extinciones de la llamada megafauna de la Era de Hielo y la de los parientes extintos del ser humano. En el capítulo VII se abordan las historias de extinción de algunas especies contemporáneas al hombre, y finalmente, en los episodios VIII y IX, se aborda la manera en la que la ciencia enfrenta el problema de las extinciones modernas.

Evolution, Explanation, Ethics and Aesthetics: Towards a Philosophy of Biology focuses on the dominant biological topic of evolution. It deals with the prevailing philosophical themes of how to explain the adaptation of organisms, the interplay of chance and necessity, and the recurrent topics of emergence, reductionism, and progress. In addition, the extensively treated topic of how to explain human nature as a result of natural processes and the encompassed issues of the foundations of morality and the brain-to-mind transformation is discussed. The philosophy of biology is a rapidly expanding field, not more than half a century old at most, and to a large extent is replacing the interest in the philosophy of physics that prevailed in the first two-thirds of the twentieth century. Few texts available have the benefit of being written by an eminent biologist who happens to be also a philosopher, as in this work. This book is a useful resource for seminar courses and college courses on the philosophy of biology. Researchers, academics, and students in evolutionary biology, behavior, genetics, and biodiversity will also be interested in this work, as will those in human biology and issues such as ethics, religion, and the human mind, along with professional philosophers of science and those concerned with such issues as whether evolution is compatible with religion and/or where morality comes from. - Presents the unique perspective of a distinguished biologist with extensive experience in the field who has published much about the subject in a wide variety of journals and edited volumes - Covers the philosophical issues related to evolution and biology in an approachable and readable style - Includes the most up-to-date treatment of this burgeoning, exciting field within biology - Provides the ideal guide for researchers, academics, and students in evolutionary biology, behavior, genetics, and biodiversity

Personal genomics services such as 23andMe and Ancestry.com now offer what once was science fiction: the ability to sequence and analyze an individual's entire genetic code—promising, in some cases, facts about that individual's ancestry that may have remained otherwise lost. Such services draw on and contribute to the science of human population genetics that attempts to reconstruct the history of humankind, including the origin and movement of specific populations. Is it true, though, that who we are and where we come from is written into the sequence of our genomes? Are genes better documents for determining our histories and identities than fossils or other historical sources? Our interpretation of gene sequences, like our interpretation of other historical evidence, inevitably tells a story laden with political and moral values. Focusing on the work of Henry Fairfield Osborn, Julian Sorell Huxley, and Luigi Luca Cavalli-Sforza in paleoanthropology, evolutionary biology, and human population genetics, History Within asks how the sciences of human origins, whether through the museum, the zoo, or the genetics lab, have shaped our idea of what it means to be human. How have these biologically based histories influenced our ideas about nature, society, and culture? As Marianne Sommer shows, the stories we tell about bones, organisms, and molecules often change the world.

'Advances in Genetics Research'presents original research results on the leading edge of genetics discovery. Each article has been carefully selected in an attempt to present substantial research results across a broad spectrum. In this continuing series compilation, the authors present and discuss the most recent Y chromosome progress within the main fields of genetics; male infertility associated with TTTY gene family deletions in the Y chromosome; genetic diversity assessment by random amplified polymorphic DNA; the effect of habitat fragmentation on genetic diversity; the use of HeLa cells as a model for studying DNA damage and repair; the molecular genetics of polycythemia vera; recent advances and molecular background of microRNAs in disease; papaya viral diseases; phylogenetics and phylogeography of large neotropical rodents by means of mitochondrial genes; and omics technologies applied to prokaryotes.

This book collects the contributions to the symposium'The current state of evolutionary archeology in Argentina'that was held in Buenos Aires, for celebrating the 200th anniversary of Charles Darwin's birth and the 150th anniversary of the publication of'On the Origin of Species'. The meeting was sponsored by the IMHICIHU-CONICET (Instituto Multidisciplinario de Historia y Ciencias Humanas-Consejo Nacional de Investigaciones Cientificas y Tecnicas). Contents: PREFACE (Hernan J. Muscio and Marcelo Cardillo); INTRODUCTION (Hernan J. Muscio and Marcelo Cardillo); CULTURAL ADAPTATIONS: IS IT CONCEPTUALLY COHERENT TO APPLY NATURAL SELECTION TO CULTURAL EVOLUTION? (Santiago Ginnobili); THEORY OF CLASSIFICATION AND TAXONOMICAL SCHOOLS: A SYNTHESIS FOR ARCHAEOLOGY (Daniel Garcia Rivero); ENVIRONMENT, SPACE, HISTORY, AND TECHNOLOGICAL EVOLUTION. THE CASE OF THE PATAGONIAN COAST (Marcelo Cardillo); ON THE PROBLEM OF IDENTIFYING HOMOLOGIES IN LITHIC ARTIFACTS (Gustavo Barrientos); LOCAL EXTINTION, POPULATION DYNAMICS AND ARCHAEOLOGICAL PATTERNS OF CULTURAL EVOLUTION: A CASE STUDY IN THE NORTH PUNA OF ARGENTINA (Hernan Muscio); HUMAN HOLOCENE COLONIZATION, DIET BREADTH AND NICHE CONSTRUCTION IN SIERRAS OF CORDOBA [ARGENTINA] (Diego Rivero and Matias Medina); THE DEVELOPMENT OF A LEGACY: EVOLUTION, BIOGEOGRAPHY AND ARCHAEOLOGICAL LANDSCAPES (Juan Bautista Belardi, Ramiro Barberena, Rafael Goni and Anahi Re)

This book presents a collection of papers from experts in a broad range of disciplines, including history, archaeology, genetics, and linguistics, to provide a detailed understanding of the Vikings in peace and in war. It focuses on one particularly exciting area of the Viking world, namely the north-west section of England, where they are known to have settled in large numbers. The 12 integrated studies in this book are designed to reinvigorate the search for Vikings in this crucial region and to provide must-reading for anyone interested in Viking history.

Molecular anthropology uses molecular genetic methods to address questions and issues of anthropological interest. More specifically, molecular anthropology is concerned with genetic evidence concerning human origins, migrations, and population relationships, including related topics such as the role of recent natural selection in human population differentiation, or the impact of particular social systems on patterns of human genetic variation. Organized into three major sections, An Introduction to Molecular Anthropology first covers the basics of genetics – what genes are, what they do, and how they do it – as well as how genes behave in populations and how evolution influences them. The following section provides an overview of the different kinds of genetic variation in humans, and how this variation is analyzed and used to make evolutionary inferences. The third section concludes with a presentation of the current state of genetic evidence for human origins, the spread of humans around the world, the role of selection and adaptation in human evolution, and the impact of culture on human genetic variation. A final, concluding chapter discusses various aspects of molecular anthropology in the genomics era, including personal ancestry testing and personal genomics. An Introduction to Molecular Anthropology is an invaluable resource for students studying human evolution, biological anthropology, or molecular anthropology, as well as a reference for anthropologists and anyone else interested in the genetic history of humans.

Written for non-experts, this volume introduces the mechanisms that underlie reticulate evolution. Chapters are either accompanied with glossaries that explain new terminology or timelines that position pioneering scholars and their major discoveries in their historical contexts. The contributing authors outline the history and original context of discovery of symbiosis, symbiogenesis, lateral gene transfer, hybridization or divergence with gene flow and infectious heredity. By applying key insights from the areas of molecular (phylo)genetics, microbiology, virology, ecology, systematics, immunology, epidemiology and computational science, they demonstrate how reticulate evolution impacts successful survival, fitness and speciation.Reticulate evolution brings forth a challenge to the standard Neo-Darwinian framework, which defines life as the outcome of bifurcation and ramification patterns brought forth by the vertical mechanism of natural selection. Reticulate evolution puts forward a pattern in the tree of life that is characterized by horizontal mergings and lineage crossings induced by symbiosis, symbiogenesis, lateral gene transfer, hybridization or divergence with gene flow and infective heredity, making the “tree of life” look more like a “web of life.” On an epistemological level, the various means by which hereditary material can be transferred horizontally challenges our classic notions of units and levels of evolution, fitness, modes of transmission, linearity, communities and biological individuality.The case studies presented examine topics including the origin of the eukaryotic cell and its organelles through symbiogenesis; the origin of algae through primary and secondary symbiosis and dinoflagellates through tertiary symbiosis; the superorganism and holobiont as units of evolution; how endosymbiosis induces speciation in multicellular life forms; transferrable and non-transferrable plasmids and how they symbiotically interact with their host; the means by which pro- and eukaryotic organisms transfer genes laterally (bacterial transformation, transduction and conjugation as well as transposons and other mobile genetic elements); hybridization and divergence with gene flow in sexually-reproducing individuals; current (human) microbiome and viriome studies that impact our knowledge concerning the evolution of organismal health and acquired immunity; and how symbiosis and symbiogenesis can be modelled in computational evolution.

This book provides an introduction to the latest gene mapping techniques and their applications in biomedical research and evolutionary biology. It especially highlights the advances made in large-scale genomic sequencing. Results of studies that illustrate how the new approaches have improved our understanding of the genetic basis of complex phenotypes including multifactorial diseases (e.g., cardiovascular disease, type 2 diabetes, and obesity), anatomic characteristics (e.g., the craniofacial complex), and neurological and behavioral phenotypes (e.g., human brain structure and nonhuman primate behavior) are presented.Topics covered include linkage and association methods, gene expression, copy number variation, next-generation sequencing, comparative genomics, population structure, and a discussion of the Human Genome Project. Further included are discussions of the use of statistical genetic and genetic epidemiologic techniques to decipher the genetic architectureof normal and disease-related complex phenotypes using data from both humans and non-human primates.

Gonorrhea. Bed bugs. Weeds. Salamanders. People. All are evolving, some surprisingly rapidly, in response to our chemical age. In Unnatural Selection, Emily Monosson shows how our drugs, pesticides, and pollution are exerting intense selection pressure on all manner of species. And we humans might not like the result. Monosson reveals that the very code of life is more fluid than once imagined. When our powerful chemicals put the pressure on to evolve or die, beneficial traits can sweep rapidly through a population. Species with explosive population growth—the bugs, bacteria, and weeds—tend to thrive, while bigger, slower-to-reproduce creatures, like ourselves, are more likely to succumb. Monosson explores contemporary evolution in all its guises. She examines the species that we are actively trying to beat back, from agricultural pests to life-threatening bacteria, and those that are collateral damage—creatures struggling to adapt to a polluted world. Monosson also presents cutting-edge science on gene expression, showing how environmental stressors are leaving their mark on plants, animals, and possibly humans for generations to come. Unnatural Selection is eye-opening and more than a little disquieting. But it also suggests how we might lessen our impact: manage pests without creating super bugs; protect individuals from disease without inviting epidemics; and benefit from technology without threatening the health of our children.

Since the publication in 1859 of Darwin's Origin of Species, debate over the theory of evolution has been continuous and often impassioned. In recent years, opponents of'Darwin's dangerous idea'have mounted history's most sophisticated and generously funded attack, claiming that evolution is'a theory in crisis.'Ironically, these claims are being made at a time when the explosion of information from genome projects has revealed the most compelling and overwhelming evidence of evolution ever discovered. Much of the latest evidence of human evolution comes not from our genes, but from so-called'junk DNA,'leftover relics of our evolutionary history that make up the vast majority of our DNA. Relics of Eden explores this powerful DNA-based evidence of human evolution. The'relics'are the millions of functionally useless but scientifically informative remnants of our evolutionary ancestry trapped in the DNA of every person on the planet. For example, the analysis of the chimpanzee and Rhesus monkey genomes shows indisputable evidence of the human evolutionary relationship with other primates. Over 95 percent of our genome is identical with that of chimpanzees and we also have a good deal in common with other animal species. Author Daniel J. Fairbanks also discusses what DNA analysis reveals about where humans originated. The diversity of DNA sequences repeatedly confirms the archeological evidence that humans originated in sub-Saharan Africa (the'Eden'of the title) and from there migrated through the Middle East and Asia to Europe, Australia, and the Americas. In conclusion, Fairbanks confronts the supposed dichotomy between evolution and religion, arguing that both science and religion are complementary ways to seek truth. He appeals to the vast majority of Americans who hold religious convictions not to be fooled by the pseudoscience of Creationists and Intelligent Design advocates and to abandon the false dichotomy between religion and real science. This concise, very readable presentation of recent genetic research is completely accessible to the nonspecialist and makes for enlightening and fascinating reading.

In this masterwork, Russell H. Tuttle synthesizes a vast research literature in primate evolution and behavior to explain how apes and humans evolved in relation to one another, and why humans became a bipedal, tool-making, culture-inventing species distinct from other hominoids. Along the way, he refutes the influential theory that men are essentially killer apes—sophisticated but instinctively aggressive and destructive beings.Situating humans in a broad context, Tuttle musters convincing evidence from morphology and recent fossil discoveries to reveal what early primates ate, where they slept, how they learned to walk upright, how brain and hand anatomy evolved simultaneously, and what else happened evolutionarily to cause humans to diverge from their closest relatives. Despite our genomic similarities with bonobos, chimpanzees, and gorillas, humans are unique among primates in occupying a symbolic niche of values and beliefs based on symbolically mediated cognitive processes. Although apes exhibit behaviors that strongly suggest they can think, salient elements of human culture—speech, mating proscriptions, kinship structures, and moral codes—are symbolic systems that are not manifest in ape niches.This encyclopedic volume is both a milestone in primatological research and a critique of what is known and yet to be discovered about human and ape potential.