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This book, like other monographs of the Cellular Organelles series, is not a comprehensive review, but an introduction to the study of cytoskeleton. Accordingly, we describe only the main facts and concepts related to cyto­ skeleton. Needless to say, selection and interpretation was influenced by the personal interests and opinions of the authors, although we attempted to be as fair as possible. We wished to familiarize the reader not only with well­ established facts, but with current unsolved problems. Therefore, the words'possibly,''maybe,''not known,'and'not clear'are much more frequent in this text than in many others. In accordance with the style of the series, relatively short lists of addi­ tional readings are given at the end of each chapter; these lists contain mostly the recent reviews and a few original papers describing certain phenomena in detail. Few references are cited in the text; these citations are given to help the reader find the source of certain new data and theories, which are not discussed at length in the reviews. In contrast, many well-established facts and widely known theories are not cited.

This series was established to create comprehensive treatises on specialized topics in developmental biology. Such volumes are especially vital in develop­ mental biology, since it is a very diverse field that receives contributions from a wide variety of disciplines. This series is a meeting-ground for the various practitioners of this science, facilitating an integration of heterogeneous infor­ mation on. specific topics. Each volume is intended to provide the conceptual basis for a comprehen­ sive understanding of its topic as well as an analysis of the key experiments upon which that understanding is based. The specialist in any aspect of devel­ opmental biology should understand the experimental background of the field and be able to place that body of information in context to ascertain where additional research would be fruitful. At that point, the creative process takes over, and new experiments are designed. This series is intended to be a vital link in that ongoing process of learning and discovery. If it facilitates schol­ arship, it will serve an important function.

International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. - Autoregulation of Angiogenesis by Cells of the Vessel Wall - Fibroblast Growth Factors as Malfunctional Signaling Factors - Structural and Functional Characteristics of the Centrosome in Gametogenesis and Early Embryogenesis of Animals - Cell and Molecular Biology of the Pars Tuberalis of the Pituitary - Polariation of the Na+, K+-ATPase in Epithelia Derived from Neuroepithelium - Desmosomes: Intercellular Adhesive Junctions Specialized for Attachment of Intermediate Filaments

International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. - The Division Apparatus of Plastids and Mitochondria - Nuclear and Cytoplasmic Gylcosylation - Microtubule-Organizing Centers and Nucleating Sites in Land Plants - The Wilms'Tumor 1 Gene: Oncogene or Tumor Supressor Gene? - Exocytosis in Chromaffin Cells of the Adrenal Medulla