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This classic reference examines the mechanisms driving adhesion, categories of adhesives, techniques for bond formation and evaluation, and major industrial applications. Integrating recent innovation and improved instrumentation, the work offers broad and comprehensive coverage. This edition incorporates several new adhesive classes, new application topics, and recent developments with nanoadhesives and bio-based adhesives. Existing chapters are thoroughly updated, revised, or replaced and authored by top specialists in the field. Abundant figures, tables, and equations appear throughout the work.

High throughput screening remains a key part of early stage drug and tool compound discovery, and methods and technologies have seen many fundamental improvements and innovations over the past 20 years. This comprehensive book provides a historical survey of the field up to the current state-of-the-art. In addition to the specific methods, this book also considers cultural and organizational questions that represent opportunities for future success.Following thought-provoking foreword and introduction from Professor Stuart Schreiber and the editors, chapters from leading experts across academia and industry cover initial considerations for screening, methods appropriate for different goals in small molecule discovery, newer technologies that provide alternative approaches to traditional miniaturization procedures, and practical aspects such as cost and resourcing. Within the context of their historical development, authors explain common pitfalls and their solutions.This book will serve as both a practical reference and a thoughtful guide to the philosophy underlying technological change in such a fast-moving area for postgraduates and researchers in academia and industry, particularly in the areas of chemical biology, pharmacology, structural biology and assay development.

Your personal Ullmann's: Chemical and physical characteristics, production processes and production figures, main applications, toxicology and safety information are all to be found here in one single resource - bringing the vast knowledge of the Ullmann's Encyclopedia to the desks of industrial chemists and chemical engineers. The ULLMANN'S perspective on polymers and plastics brings reliable information on more than 1500 compounds and products straight to your desktop Carefully selected'best of'compilation of 61 topical articles from the Encyclopedia of Industrial Chemistry on economically important polymers provide a wealth of chemical, physical and economic data on more than 1000 different polymers and hundreds of modifications Contains a wealth of information on the production and use of all industrially relevant polymers and plastics, including organic and inorganic polymers, fibers, foams and resins Extensively updated: more than 30% of the content has been added or updated since the launch of the 7th edition of the Ullmann's encyclopedia in 2011 and is now available in print for the first time 4 Volumes

In recent years many of the conventional methods of insect control by broad­ spectrum synthetic chemicals have come under scrutiny because of their unde­ sirable effects on human health and the environment. In addition, some classes of pesticide chemistry, which generated resistance problems and severely affected the environment, are no longer used. It is against this background that the authors of this book present up-to-date findings-relating to biochemical sites that can serve as targets for developing insecticides with selective prop­ erties, and as the basis for the elucidation of resistance mechanisms and countermeasures. The book consists of eight chapters relating to biochemical targets for insec­ ticide action and seven chapters relating to biochemical modes of resistance and countermeasures. The authors of the chapters are world leaders in pesti­ cide chemistry, biochemical modes of action and mechanisms of resistance. Biochemical sites such as chitin formation, juvenile hormone and ecdysone receptors, acetylcholine and GABA receptors, ion channels, and neuropeptides are potential targets for insecticide action. The progress made in recent years in molecular biology (presented in depth in this volume) has led to the iden­ tification of genes that confer mechanisms of resistance, such as increased detoxification, decreased penetration and insensitive target sites. A combina­ tion of factors can lead to potentiation of the resistance level. Classifications of these mechanisms are termed gene amplification, changes in structural genes, and modification of gene expression.