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The agricultural food system needs to provide access to enough healthy and affordable food for the growing population and mitigate its impact on the planet for future generations. Emerging technologies can help farmers increase yields.The book presents theoretical and applied aspects of nanotechnology and biotechnology. It also includes topics on management and food security.

Today's fast-moving world of science will have far-reaching effects on all of our lives. Trends in Science is a series of of essential readings for anyone who wants to know more about how his or her future will be affected; as well, the series provides accessible and stimulating material for high school and college students, for researchers and librarians. All titles in the series provide: an introductory overview of the field in the last 100 years, reviewing the past but also predicting the new developments of the future; a detailed chronology of the most important milestones; an index of key terms and concepts; biographies of the most important scientists in each field and their role in shaping their particular branch of science; a listing of important Websites, a directory of organizations, and suggestions for further reading.

Many of the natural products have been isolated and characterized from the actinobacteria, for example polyketides, phenazines, peptides, indolocarbarbazoles, and sterols. To explore new antibiotics from actinobacteria, several bioinformatics and synthetic biology tools were developed. This book covers basics to recent protocols for drug discovery from actinobacteria.Features: Discusses the benefits of production of antibiotics and enzymes from actinomycetes in a large scale Covers the synthetic biology approach Describes the strain improvement of actinobacteria Gives information on basic isolation of actinobacteria and modern techniques Covers the applications and metabolic engineering strategies of actinomycetes This book will be helpful for the pharmaceutical industries and researchers to develop new antibiotics from actinobacteria and can be used in support of future research in drug discovery.

Chemistry: An Introduction to General, Organic and Biological Chemistry is the ideal resource for today's allied health and nursing students. Author Karen Timberlake fosters development of problem-solving skills while helping you visualize and understand concepts. She assumes no prior knowledge of chemistry, as she engages you in seeing the connections between chemistry, the world around you and your future careers. The 14th Edition presents new problem-solving strategies, current Chemistry in Health topics and updated content to reflect the diversity of the health care community.

Seager/Rye-McCurdy/Yoder's FUNDAMENTALS OF CHEMISTRY FOR TODAY helps you hone your critical-thinking skills with ample problem-solving opportunities throughout the text. Fresh examples won't bog you down with incessant repetition, and new figures relevant to health professions add context and color to the core source material. FUNDAMENTALS OF CHEMISTRY FOR TODAY covers all the necessary components of the GOB curriculum in sufficient depth to prepare you for future studies.

Natural products are a marvel of evolution. Plants are chemical factories and have produced a vast number of highly diverse and interesting natural substances with their extraordinary properties, which we humans have been using for centuries to relieve and cure diseases. At the latest since the discovery of penicillin, natural substances have become an important source of medicines, but we know only very few of the presumably many millions that are still waiting to be discovered. Important antibiotics, immunosuppressants, anticancer agents, hormones, and antiviral agents are among the natural products. But do natural products still matter in the age of biotechnology and genetic engineering? Yes, more than ever, because medicinal chemists draw creative inspiration for their syntheses from nature to develop the next blockbuster in medicine. Oliver Kayser tells the story of natural products and medicinal plants in this book in a highly informative and amusing way from a new perspective. He explores how natural products from naturopathy gave birth to the pharmaceutical industry, how they shaped our society as medicines and remedies, enabled wars, and paved the way to Nobel Prizes. The author paints a fascinating panorama of natural product chemistry in plants, microorganisms, and animals. Starting with the first isolations at the beginning of the industrial revolution, he leads us with the ideas and enthusiasm of many scientists into the modern era of drug testing, computer chemistry, and the highly successful serendipitous discoveries of active ingredients. Natural product research in the laboratory has an enormous impact on our lives today. The author offers a glimpse over the shoulder of how the search for the new drugs of tomorrow works today. This book is the ultimate book from the pen of a scientist deeply rooted in research, providing the reader with an enlightening and at the same time entertaining insight into how scientists think and how arduous research can be.

Chinese Materia Medica - Chemistry, Pharmacology and Applications provides comprehensive and up-to-date information on the chemistry and pharmacology of commonly-used Chinese herbs. It gives an in-depth profile of the traditional experience of Chinese materia medica with modern scientific explanations. It also features the theories and concepts of Chinese materia medica from the Western medical perspectives, and the sources, production and quality control of Chinese materia medica. This book can be used both as a reference book and a textbook for specialized university and on-the-job training courses. It is essential reading for all students and practitioners of traditional Chinese medicine. It should also be of interest to those in education and research in natural products, pharmaceutical sciences and medicine.

This book discusses toxic Microcystis and the toxins from various viewpoints such as classification, cultivation, occurrences in lakes, and relations to zooplankton. The text presents new information on the chemistry, analytical chemistry, toxicology, molecular modeling, and liver tumor promotion of the toxins. Microcystis species are described in relation to morphological features, allozyme genotype, and toxin content. Seasonal changes of Microcystis population are described with special references to toxic species and composition of the toxins. Chemical characteristics of microcystins are reviewed and the process for identification of microcystins is described.

Biomolecules, also known as molecules of life, are essential for sustaining life processes. This book presents a study of these crucial biological substances to explore their function, structure, biological role, and synthesis. It also expands upon the various types of biomolecules and discusses their individual characteristics.The subject matter of this book also covers: Mucopolysaccharides Tertiary Structure of Proteins Caffeine Mechanism of Enzyme Action Biosythesis of Haemoglobin Print edition not for sale in South Asia (India, Sri Lanka, Nepal, Bangladesh, Pakistan or Bhutan)

Explore the comprehensive landscape of polymer membrane applications in this book, encompassing gas separation, organic solvent nanofiltration, water desalination, and fuel cells. The text delves into the subtle influence of polymer membranes on energy efficiency across diverse industries, spotlighting advanced variants such as bio-based, mixed matrix, and polyimides-based membranes. Offering an in-depth analysis, the book elucidates the discovery, development, and challenges associated with these state-of-the-art materials, underscoring their role in achieving enhanced performance and energy efficiency.

This book consolidates the collective contributions of various authors, presenting a diverse array of materials for systematic property assessment and their subsequent application in electronic, magnetic, and spintronic technologies. Encompassing pure and modified polymers, metals, and semiconductors, the book elucidates the magnetic, photocatalytic, thermal, electrochemical, and other salient characteristics inherent in these materials. Delving into a broad spectrum of applications such as energy storage, environmental remediation (water purification), and biomedical (drug administration), the book carefully examines these materials in the context of their distinctive attributes. By elucidating the correlation between a material's functionality and its physical properties, this work offers a lucid and accessible presentation that facilitates an understanding of how these materials can be judiciously employed for specific purposes. Designed for researchers, graduate students, educators, engineers, industry researchers, and other informed members of the public, the comprehensive coverage of this book renders it an indispensable tool in the realm of materials science and technology. Through its meticulous exploration of various materials and their applications, this work stands as a valuable resource for those seeking a profound understanding of the intricate interplay between material properties and their functionalities.

Nanotechnology can treat diseases by site-specific and target-oriented delivery of precise medicines. Nanomaterials improve the efficacy of drugs and selective diagnosis. The book covers detection and treatment. It explains the use of nanocarriers for a variety of diseases such as cardiovascular and respiratory diseases, cancer, and ulcerative colitis. It includes topical, transdermal, and ocular drug delivery and combined medication delivery.

Introduction to Chemistry ISE

This new volume provides comprehensive coverage of the family Rutaceae, emphasizing its diverse phytochemistry and medicinal uses.The volume provides an introduction to the family Rutaceae and then goes on to delineate its phytochemical and pharmacological properties and uses. Also addressed are the nutritional, clinical, and toxicological profiles of the family Rutaceae, elaborating on the nutritional value of Rutaceae plants, their healthcare and clinical applications, and their possible toxic side effects.This volume provides an information overview of the Rutaceae family, which comprises numerous ornamental as well as economically significant fruit-bearing trees with significant phytochemistry and medicinal uses that are important for new drug discovery for pharmaceutical industries. The chapters may also direct researchers to isolate/extract pure compounds from Family Rutaceae for new and novel drug discoveries.

Whole-cell biocatalysis is a promising and emerging field of biological science that is mostly based on advancements in biosystems engineering for the production of useful products such as chemicals, fuels, and pharmaceuticals. It is a unique platform that provides an efficient catalytic system at affordable cost and with low maintenance. Recent studies have proven that whole-cell catalysis is very useful in conducting many complex and complicated chemical reactions that could be executed with greater ease and in an eco-friendly manner in ambient conditions with zero/minimal ecological effect. This has made whole-cell biocatalysis very popular and a center of significance in the field of modern biological catalysis.This new volume offers a comprehensive understanding of whole-cell biocatalysis, beginning with an introduction and an overview of relevant tools and techniques. It presents the basic as well as the advanced concepts of whole-cell biocatalysis, thus acting as a complete guide for the reader. It looks at the promising developments that have taken place in the past decade and discusses the application of computational tools, the use of metabolic flux systems, and the role of metabolic networks for the cell system development for whole-cell catalysis. The chapters explore whole-cell biocatalysis for the production of chemicals, of fuels, and for environmental restoration, with case studies and success stories that showcase new developments in the technology.This volume provides a valuable presentation of whole-cell biocatalysis for graduate students, faculty, industry professionals, and others working in biochemistry and bio-systems engineering.

Ocean plays a significant role in energy production, human health and economy. Seawater, seaweed, microalgae, yeast, bacteria act as feedstock for biofuels and bioproducts. This book focuses on the application of marine biomass for production of energy, fertilizers, nutraceuticals, pharmaceuticals, cosmetics, bioplastics and other value-added products. It presents technological advancements and optimization strategies for enhancing process efficiency, overcoming challenges and maximizing the potential of marine-based biorefinery. It also describes how marine resources can be applied to wastewater treatment, eco-restoration, environment protection and sustainable development.

The term nutraceuticals is applied to the products isolated from the herbal sources, nutrients or dietary supplements, processed foods, (cereals, soup and beverages) and specific diets, that may also used as medicine other than nutrition. It usually refers to the foods derived products which may sell in medicinal form, possessing physiological benefits to the host while promoting health and wellness and provide protection against chronic disorders. They may also increase the life expectancy, delay the aging and/or support the structure and function of the body organs. Demand for nutraceuticals with potential to prevent and treat chronic disorders has been interestingly increasing over the past few years. Based on food sources, nutraceuticals are classified into dietary fibers, probiotics, prebiotics, polyunsaturated fatty acids (PUFAs), vitamins, polyphenols and spices. A dietary supplement is generally considered as product containing vitamins, minerals, amino acids, and medicinal plants that are indented to be used to supplement the diet or a concentrate, metabolite, constituent, extract, or combinations of these ingredients. Broadly, nutraceuticals are any of these ingredients or supplements using for health purposes other than nutrition. This book on the fundamentals of Nutraceuticals is organized in two parts i.e., the introductory aspects of macro- and micro-nutrients, gut microbiota regulation, nutraceuticals and drug interactions, while the second part is focusing on the biological benefits of nutraceuticals in different disease states. Besides, this book is also addressing the safety aspects of nutraceuticals and phytotherapeutic support in pregnancy. Including contributions from the experts in the field, target audience (pharmacists, nutritionists, other healthcare providers, and researchers in food and nutrition sector) will be benefited with the updated literature on nutraceuticals and dietary supplements.

Since 1984 this book, now in its 7th edition and thoroughly updated, has introduced the crucial interface between our diet and the essentially chemical nature of what we eat and drink. The contributions of the various classes of natural food components, as well as additives and contaminants, to the nutritional value of foods are considered. These include the nutrients required in large amounts like carbohydrates, proteins, fat, minerals and water as well as the less bulky nutrients such as vitamins, flavours, colours and preservatives. Undesirable food components, including allergens, pesticide residues and toxins are also dealt with. Not just the nature of food components are described, but also how they behave in storage, processing and cooking and accompanying changes in a food's nutritional value. The book features a ‘Special Topics'section at the end of each chapter for specialist readers and advanced students, comprehensive listings of up-to-date review articles and recommended books for further reading, an exhaustive index and the structural formulae of over 500 food components. Frequent reference is also made to wider food and health issues, e.g. lactose intolerance, polyunsaturated fatty acids, wheat and gluten evolution, salt and hypertension, flavonoids in tea and fruit, and the increasing replacement of artificial with natural food colours. Food: The Chemistry of its Components will be of particular interest to students and teachers of food science, nutrition and applied chemistry in universities, colleges and schools. Its accessible style ensures that it will be invaluable to anyone with an interest in food issues. Extracts from reviews of previous editions:“A superb book to have by your side when you read your daily newspaper.” New Scientist.“… filled me with delight, curiosity and wonder. All the chemistry is very clear and I thoroughly recommend it.” The Chemical Educator.“This is a lively and thorough treatment of the subject. I can recommend it to anyone interested in food, as an excellent reference or just to pick up and browse.” School Science Review.“Especially noteworthy are the author's simple observations on foods that are familiar to us all …” Comprehensive Reviews in Food Science and Safety.

A guide examining one of the most important, yet often most neglected, organ systems in the body — from the mouth, to the stomach, to the pancreas and liver — and how to keep it healthy with herbal medicine and natural healing Digestive complaints account for around 30% of health consultations, and more than 40% of unrelated consultations end up being connected to the gut. An unhealthy gut, as well as causing gastrointestinal disorders, contributes to most other chronic health issues, ranging from neurological issues to chronic fatigue to mental health issues, as well as many more. And although a functioning digestive system is imperative for energy, intelligence, happiness and survival, it is often one of the most poorly understood and mistreated systems in the human body. In her twenty five years of herbal practice, Christine Herbert has treated a plethora of patients, whose issues more often than not stemmed from problems with digestion. In Digestion, the Key to Good Health Herbert condenses this wisdom into a pioneering guide on how to maintain a normal, healthy gut. The book sets out discussing the whole digestive process, from top to bottom, exploring all the organs and tissues involved. It moves on to discuss symptoms to be aware of that something is amiss with digestion and the gut, addressing a range of specific conditions such as reflux and GORD, mouth ulcers, IBS, leaky gut, haemorrhoids and many more. Herbert concludes Digestion, the Key to Good Health by exploring herbs that assist healthy digestion, condensed into a materia medica for ease of reference, along with other natural ways to help digestion. Digestion, the Key to Good Health is an essential guide for all herbalists, naturopaths and nutritionists to assist with their diagnosis and treatment of both digestive issues and the wider impact of the digestive system on chronic illnesses. The clear and accessible prose will also appeal to anyone looking to maintain a healthier digestive system and understand the functioning of their own body more deeply.

Since the discovery and successful deployment of salvarsan to treat syphilis, as well as cisplatin as a cancer drug, the field of metallodrugs has been flourishing. In addition to therapeutic applications, metals and metal-containing molecules have properties, such as an electrochemical or an optical signal, that can be used to diagnose biologically relevant molecules or unravel cellular metabolism. Moreover, metals are part of the essential elements for life, and of increased attention in nutraceuticals. Most of the current diagnosis processes, therapeutics, and nutraceuticals are based on organic molecules. MILS-26 reviews in 7 comprehensive chapters, written by 20 experienced authors, the most recent metal-containing molecules and nanomaterials for diagnosis and therapy.Features: The field of metallodrugs has been flourishing and this area of research can be used to diagnose specific biologically relevant molecules or unravel cellular metabolism. The authors are preeminent bioinorganic and medicinal inorganic chemists and review the most current research in this field. The book discusses the properties and therapeutic applications of metals and metal-containing molecules including the use of electrochemical or optical signal for diagnosis of biologically relevant molecules. It endorses and stimulates research in the vibrant field of biological inorganic chemistry. It reviews the most current research supporting the relevance of metal-containing molecules and nanomaterials for diagnosis and therapy.

This volume provides an overview of the biochemical basis of metabolic diseases and molecular basis of chemical pathologies. Metabolic disorders occur when metabolic processes in the body are disrupted. They contribute a significant burden to human health globally. They can be congenital or acquired, for example, diabetes mellitus, obesity, metabolic syndrome, osteoporosis, osteopenia, mild-moderate hypovitaminosis D, erectile dysfunction, dyslipidemia, and thyroiditis. Metabolic disorders have gained significant importance due to the exponential increase in obesity worldwide. Early diagnosis of metabolic disorders is important in order to employ lifestyle and risk factor modification.Features: An overview of the biochemical basis of metabolic diseases and molecular basis of chemical pathologies Describes recent trends in diagnosis of metabolic disorders Discusses management and treatment of metabolic diseases Allows quick identification and retrieval of material by researchers learning the efficacy, associated dosage and toxicity of each of the classes of compounds Suitable globally for graduate and postgraduate students studying metabolic diseases

The goal of the American Chemical Society's Chemistry in Context is to establish chemical principles on a need-to-know basis for non-science majors, enabling them to learn chemistry in the context of their own lives and significant issues facing science and the world. The non-traditional approach of Chemistry in Context reflects today's technological issues and the chemistry principles within them. Climate change, renewable energy, alternate fuels, nutrition, and genetic engineering are examples of issues that are covered in Chemistry in Context.

The second edition of The Chemistry of Clay-Organic Reactions book provides a comprehensive and fully updated summary of the literature on the interactions of clay minerals with organic molecules, including reaction mechanisms and bonding modes together with their practical and industrial applications. The reader will gain an insight into the formation and properties of complexes between clay minerals and a variety of organic compounds and the use of such complexes as sorbents and carriers of organic pollutants, pesticides, dyes, and pharmaceuticals.KEY FEATURES An authoritative resource providing a detailed synthesis of published data on clay-organic complexes and reactions. Authored by a globally recognized expert in the field. Describes developments in the interactions of organic compounds with fibrous and short-range order clay minerals. This book is written for environmental and industrial chemists, organic geochemists, and soil scientists, and it will appeal to academics, researchers, industry professionals, and graduate students.

Zinc: Early Development, Applications, and Emerging Trends is a comprehensive book covering various aspects of the metallic element zinc that has a significant role in the growth and survival of humans. The United Nations Organization has aptly declared it as a ‘Life-Saving Material'since it helps in overcoming infections and strengthening the immune system. Zinc is an essential element next to iron, aluminum, and copper with abundant presence in nature, and is worth billions of dollars commercially. Besides the metal, its compounds and nanoparticles have also become attractive to researchers due to their enormous applications. The industrial and agricultural uses of the metal and its compounds are widespread.An exclusive book covering all important aspects of zinc is yet to hit the market. This book, with contributions from experts in geology, chemistry, medicine (including dentistry and traditional systems), agriculture, veterinary science, biology, bioinformatics, and nanotechnology encompassing the latest developments in their fields related to zinc, fills this void. The uniqueness of the book is its interdisciplinary nature and potential use by researchers, students, and teachers of various specialties.Features: Contributes to a better understanding of the complexities of zinc's role in various branches of science Contains basic and practical information for a wider audience and researchers of different fields besides those interested in zinc Provides detailed information on the usefulness of zinc in prophylaxis and treatment of diseases in modern medicine, dentistry, and traditional systems such as Ayurveda, Siddha, and Unani, as well as veterinary medicine Highlights zinc's role in agriculture and food science with various crops and nutritive materials Includes chapters on fast-growing areas – nanotechnology and bioinformatics

This volume in the popular series, Drugs and the Pharmaceutical Sciences, begins with the history of cancer treatment, carcinogens, and molecular mechanisms involved in cancer pathogenesis. It incudes conventional and advanced cancer therapies ranging from oral and parenteral preparations to advanced fabricated systems such as nanoparticles, liposomes, antibodies, aptamers, poly(amidoamine) and photodynamic therapies. The preparation and mechanisms of molecular targeting of cancer are presented and the authors focus on a diverse audience including undergraduates and research students.Features Timely coverage of changes in process control technology for the phamaceutical industry, a dynamic area in terms of products and manufacturing processes Provides an update on the unique requirements of these industries and how they differ from others, for example the microelectronics or specialized chemicals industries Draws on the author's vast experience in the field of industrial hygiene and hazardous materials Presents a collection of unique situations in which industrial hygiene was implemented to resolve a variety of scenarios and did not interfere with quality issues Addresses current topics relating to industry evolution such as migration of therapies to higher potency, RiskMAP, new modalities in medicines and treatments, large molecule therapeutics and conjugates

První díl učebnice je určen zahraničním i českým studentům, kteří se připravují na studium lékařství, farmacie, veterinárního lékařství a přírodovědných oborů, kde chemie není hlavním předmětem studia. Kniha shrnuje základní poznatky z obecné, anorganické a organické chemie. Kapitoly jsou doplněny otázkami k opakování učiva a příklady k důkladnému procvičení probrané látky. Počáteční kapitoly jsou přizpůsobeny jazykovým znalostem zahraničních studentů.

This book highlights all newly reported carbon nanostructures including graphene and its derivatives, carbon nanotubes, metal organic frameworks, fullerenes, nanorods, nanospheres, nano onions, porous nanoparticles, nanohorns, nanofibers and nanoribbons, nanodiamonds, graphitic carbon nitrides, carbon aerogels and hydrogels, graphdiyne and graphenylene. It presents the historical development of carbon nanostructures technologies, different types and classifications, and different fabrication and functionalization techniques, including outer/inner surface functionalization and covalent and noncovalent functionalization. This Handbook discusses the unique properties of functionalized carbon nanostructures that can be obtained by modifying their structures, composition, and surface. It gives the reader an in-depth look at the current achievements of research and practice while pointing you ahead to new possibilities in functionalizing and using carbon nanomaterials. Finally, it covers the various applications of functionalized carbon nanostructures including adsorbents, additives, active materials in energy accumulating systems (batteries, hydrogen storage systems, and supercapacitors), filtering media, catalysts or supports for catalysts, sensors or substrates for sensors, additives for polymers, ceramic composites, metal and carbon alloys, glasses, digital textiles, and composite materials.

This comprehensive resource skillfully consolidates crystal engineering, the design of organic solids, and supramolecular synthons (i.e., structural hydrogen bond units) to achieve desired pharmaceutical properties, including solubility, dissolution, bioavailability, permeability, particle size, tableting, hydration, and mechanical strength. Covering 30 years of crystal engineering developments and pharmaceutical applications, this book will be a single and complete resource for supramolecular and structural chemists, the crystal engineering community, pharmaceutical scientists, and industrial researchers.Key Features Covers the fundamentals of crystal engineering and supramolecular synthons. Details the challenges of low solubility and low permeability facing oral drug formulations. Explains how heterosynthons provide a rational approach to address and implement solutions. Provides case studies from academic and industrial labs to walk the reader through the actual steps. Explores developments in the scale up and manufacture of crystal forms in pharmaceutical industry.

Die phänomenologische Thermodynamik ist von wenigen grundlegenden Observablen, Konzepten und Zusammenhängen bestimmt, die nicht einfach zu vermitteln sind, besonders dann, wenn die notwendige mathematische Vorstellung und Fähigkeit der Studierenden an Grenzen stößt. Das vorliegende Lehr- und Übungsbuch „Chemische Thermodynamik'vermittelt Studierenden im Haupt- und Nebenfach Chemie anschaulich polytrope Zustandsänderungen, Reaktions- und Phasengleichgewichte, Oberflächen und Grenzflächen sowie Verfahren und Vergleich von herkömmlicher und moderner Energiegewinnung und Bioenergetik. Ideal zur Prüfungsvorbereitung sind die rund 500 explizit gelösten Fragen und Aufgaben, u.a. zu idealen und realen Gasen, zur Bioenergetik etc., und der lerndidaktisch förderliche Anspruch auf Parallelität von prägnanter Fassung der Theorie und extensiver fächerintegrierender Übung. Neu in der 4., umfassend überarbeiteten und ergänzten Auflage: - Zusätzliche Kapitel zu schadstofffreien Emissionen, thermischer Analyse und Umwandlungsketten von grünem Wasserstoff als klimaneutraler Brennstoff der deutschen Energiewende. - Zusätzliche Übungsaufgaben und Lösungen. - Optimal zur Prüfungsvorbereitung und darüber hinaus.

Completely revised and updated, this fourth edition elucidates the principles of pharmaceutics, biopharmaceutics, dosage form design, and drug delivery – including emerging new biotechnology-based treatment modalities. The authors integrate aspects of physical pharmacy, chemistry, biology, and biopharmaceutics into drug delivery.With the expiration of older patents and generic competition, the biopharmaceutical industry is evolving faster than ever. Consequently, this edition of the book emphasizes the heightened focus that the recent remarkable progress in gene editing, immunotherapy, and nanotechnology has brought to the design of new drugs and diagnostic approaches along with novel dosage forms.Apart from new chapters, this edition highlights the emerging emphasis on the role of artificial intelligence (AI) in drug discovery, mRNA and antibody-based therapies, genome editing, immunotherapy, chemical kinetics, and the stability of drug products.Features: · Includes new chapters on antibody therapeutics, gene editing, and immunotherapy.· Explains newer approaches and future methods and the significance of artificial intelligence (AI) in drug discovery. · Updated sections on pharmacy mathematics, chemical kinetics, and the stability of medicinal products. · Important updates on parenteral drug products, protein and peptide treatments, and biotechnology-based pharmaceuticals to provide a contemporary perspective on drug development, delivery, and pharmaceutical sciences.· Expansion of review questions and answers to clarify concepts for students and add to their grasp of key concepts covered in this book.Although there are numerous books on pharmaceutics and dosage forms, most cover different areas of the discipline and do not provide an integrated approach. The integrated approach of this book not only provides a singular perspective of the overall field, but also supplies a unified source of information for students, instructors, and professionals, saving their time and money.•

Romanian ethnomedicinal knowledge extends as far back as the 16th century to the Geto-Dacian priests who used medicinal plants and practiced integrated holistic medicine. The ethnomedicine continued in monasteries by monks who used cultivated medicinal plants and wild harvested plants. There are now over 800 species of medicinal plants in Romania. An earlier work last century entitled “Pharmaceutical Botany: the Culture and Harvest of Pharmaceutical Plants” by Grinţescu refers to approximately 500 Romanian healing plants, although most of them are not recognized in modern medicine. There is clear evidence of ethnomedicine in this important region, particularly those that are endangered.Features: Provides an understanding of indigenous plant-derived natural medicines of Romania Discusses selected plant families that are representative members of the most important medicinal plants in the region Includes discussions and critical views on the potential and challenges for further development of the selected plants in a modern setting Details the important plants and organizes the chapters based on either taxonomy or medical use Covers traditional and folk medicine of Romania

Naturstoffe sind ein Wunderwerk der Evolution. Pflanzen sind chemische Fabriken und haben mit ihren außergewöhnlichen Eigenschaften eine riesige Anzahl sehr vielfältiger interessanter Naturstoffe hervorgebracht, die wir Menschen seit Jahrhunderten zur Linderung und Heilung von Krankheiten nutzen. Spätestens seit der Entdeckung des Penicillins sind Naturstoffe zu einer wichtigen Quelle für Medikamente geworden, aber wir kennen nur sehr wenige der vermutlich vielen Millionen, die auf ihre Entdeckung warten. Zu den Naturstoffen gehören wichtige Antibiotika, Immunsuppressiva, Antikrebsmittel, Hormone und auch antivirale Wirkstoffe. Aber haben Naturstoffe im Zeitalter der Bio- und Gentechnologie überhaupt noch eine Bedeutung? Ja, mehr denn je, denn Medizinalchemiker holen sich kreative Anregungen für ihre Synthesen aus der Natur, um den nächsten Blockbuster in der Medizin zu entwickeln. Oliver Kayser erzählt in diesem Buch die Geschichte der Naturstoffe und Medizinpflanzen auf höchst informative und amüsante Weise aus einem neuen Blickwinkel. Er geht der Frage nach, wie Naturstoffe aus der Naturheilkunde die pharmazeutische Industrie ins Leben riefen, wie sie als Arznei- und Heilmittel unsere Gesellschaft prägten, wie sie Kriege ermöglichten und den Weg zu Nobelpreisen ebneten. Der Autor zeichnet ein faszinierendes Panorama der Naturstoffchemie in Pflanzen, Mikroorganismen und Tieren. Beginnend mit den ersten Isolierungen zu Anfang der industriellen Revolution führt er uns mit den Ideen und der Begeisterung vieler Wissenschaftlerinnen und Wissenschaftler in die Moderne der Wirkstofftests, der Computerchemie und der höchst erfolgreichen Zufallsentdeckungen von Wirkstoffen. Die Naturstoffforschung im Labor hat einen enormen Einfluss auf unser heutiges Leben. Der Autor lässt sich über die Schulter schauen, wie heute die Suche nach den neuen Medikamenten von morgen funktioniert. Das Buch ist das ultimative Buch aus der Feder eines Wissenschaftlers, der tief in der Forschung verwurzelt ist und dem Leser einen erhellenden und zugleich kurzweiligen Einblick gibt, wie Wissenschaftler ticken und wie mühsam Forschung sein kann.

Green Solvents in Organic Synthesis Essential reference on replacing conventional solvents with greener alternatives in industrial chemicals synthesis and production A well-timed book promoting sustainability in synthesis and production of chemicals, Green Solvents in Organic Synthesis details various green solvents, solvent systems, and solubilization techniques, including their chemistry, physiochemical properties, performance, and distinct applications, presenting a greener approach to conventional solvents by replacing them with sustainable alternatives that have similarities in their reaction mechanisms. Edited by four highly qualified academics with significant research experience in the field, Green Solvents in Organic Synthesis includes information on: Water and liquid polymers (Polyethylene glycol PEG), Acetonitrile, DMSO, Dimethyl carbonate, Ionic liquids, and Supercritical fluids)Bio-based solvents (Cyrene, γ-Valerolactone (GVL), Lactic acid, 2-MeTHF) and deep eutectic solvents (DESs)Alcohols (MeOH, EtOH, i-PrOH, n-BuOH, t-BuOH, Ethylene glycol), ketones (Acetones, MEK, MIBK, Cyclohexanone), and esters (Methyl acetate, Ethyl acetate, i-PrOAc, n-BuOAc)Technical, economic, and environmental aspects of green solvents and how to maximize their reuse and recycling to alleviate pollution and reduce energy consumption For chemists in a variety of disciplines, Green Solvents in Organic Synthesis is an essential reference that provides foundational knowledge of green solvents, along with key features of each class of green solvent within the context of organic reactions for industrial and laboratory synthesis.

With Chemistry: Structure and Properties, author Nivaldo Tro tells the story of chemistry with an atoms-first approach to learning chemistry, emphasizing that matter is composed of particles and the structure of those particles determines the properties of matter. This relationship is the thread that weaves all of chemistry together and is applied to all aspects of the text. The 3rd Edition presents interactive digital features that will guide you through key concepts and the problem-solving process. Updates reflect current research on the COVID-19 vaccine and an extensive diversity, equity and inclusion review.

This book details the advances in drug discovery and delivery and the present need for emerging technologies. Throughout the text new micro and nanofabrication techniques are described, including methods such as electrohydrodynamic processes, additive manufacturing, and microfluidics, which have the potential to produce drug delivery systems that were not possible a few years ago. This book is of great use to both entry-level and experienced researchers in the field of emerging technologies for the manufacturing of drug delivery devices.Features: Describes technologies that are significantly enhancing the delivery of drugs and biologics Presents new data on mobile and wearable point-of-care testing systems Features hot topics such as electrospinning, 3D printing and micro-needles Focuses on additive manufacturing (AM) which can be used to provide customized treatment for patients Will appeal to experienced researchers and those considering entering the field of emerging technologies for the manufacturing of drug delivery devises

This textbook is written to thoroughly cover the topic of introductory chemistry in detail—with specific references to examples of topics in common or everyday life. It provides a major overview of topics typically found in first-year chemistry courses in the USA. The textbook is written in a conversational question-based format with a well-defined problem solving strategy and presented in a way to encourage readers to “think like a chemist” and to “think outside of the box.” Numerous examples are presented in every chapter to aid students and provide helpful self-learning tools. The topics are arranged throughout the textbook in a'traditional approach'to the subject with the primary audience being undergraduate students and advanced high school students of chemistry.

Due to the structural flexibility, large surface area, tailorable pore size and functional tenability, metal-organic frameworks (MOFs) can lead to materials with unique properties. This book covers the fundamental aspects of MOFs, their synthesis and modification, including their potential applications in different domains. The major focus is on applications including chemical, biosensors, catalysis, drug delivery, supercapacitors, energy storage, magnetics and their future perspectives.The volume: Covers all aspects related to metal-organic frameworks (MOFs), including characterization, modification, applications and associated challenges Illustrates designing and synthetic strategies for MOFs Describes MOFs for gas adsorption, separation and purification, and their role in heterogeneous catalysis Covers sensing of different types of noxious substances in the aqueous environment Includes concepts of molecular magnetism, tunable magnetic properties and future aspects This book is aimed at graduate students, and researchers in material science, coordination and industrial chemistry, chemical and environmental engineering and clean technologies.

Poisonous plants are used in traditional medicine systems in various healing therapies. They are a rich resource of ingredients used in herbal drug formulations that are also used in the development of synthetic drugs. They are recognized for their antioxidant, anti-inflammation, anti-cancer, and anti-diabetic activities and for many other health benefits. Exploring Poisonous Plants: Medicinal Values, Toxicity Responses, and Therapeutic Uses provides an analysis of the most important poisonous herbs, shrubs, and trees, detailing poisonous plants while demonstrating endorsements for their potential therapeutic values.Features:Presents therapeutic potentials on various poisonous herbs, shrubs, and trees.Provides descriptions of notable toxic compounds and discusses their adverse effects when consumed by animals or people.Gives practical guidance for botanical description, distribution, phytochemical constituents, pharmacological studies, and traditional and other potential uses of selected poisonous plants.This volume in the Exploring Medicinal Plants series is appropriate for scientists, researchers, and students working with poisonous plants, as well as in areas of economic botany, plant biochemistry, biotechnology, pharmacognosy, pharmaceuticals, industrial chemistry, and nanomedicine.

This volume contains eight chapters that detail advances in chemistry research. Chapter One provides an overview of published work on the electrothermal molecular absorption determination of halogens. Chapter Two focuses particularly on the microstructure characteristics of concrete containing recycled concrete aggregates (RCA). Chapter Three explores the interference of directed communications, bond components, and donor-acceptor complexes. Chapter Four highlights the recent advancements on beetroots with respect to several aspects such as its nutritional wholesomeness, commercial cultivation, chemical constituents, pharmacological activities, extraction process and an analysis of its pigments. Chapter Five introduces the study of the adsorption of DNA molecules on mixed phase-separated monolayers composed of a hydrocarbon-containing comb copolymer with an s-triazine ring and a fluorinated s-triazine derivative. Chapter Six discusses tocopherols, important isocomponents naturally found in many vegetable oils. Chapter Seven describes the structure, reactivity, and synthesis of different types of diaryliodonium salts. Lastly, Chapter Eight discusses the atomic absorption analysis method.

Nanotechnology has become very present in the field of science and scientific research. As a result, this book focuses on the green synthesis approach and latest applications of silver nanoparticles. The book also covers their potential uses in the environment, biosensing, food biotechnology, in water treatment as well as in daily life.

The new fifth edition of Chemistry: Atoms First by Burdge and Overby builds further on the success of the first four editions. The Atoms First approach provides a consistent and logical method for teaching general chemistry. This approach starts with the fundamental building block of matter, the atom, and uses it as the stepping-stone to understanding more complex chemistry topics. Once mastery of the nature of atoms and electrons is achieved, the formation and properties of compounds are developed. Only after the study of matter and the atom will students have sufficient background to fully engage in topics such as stoichiometry, kinetics, equilibrium, and thermodynamics. The text is strengthened by its offering in ALEKS, now featuring Custom Question Authoring, Video Assignments, Virtual Labs, and more!

Analytical instrumentation is crucial to research in molecular biology, medicine, geology, food science, materials science, forensics, and many other fields. Undergraduate Instrumental Analysis, 8th Edition, provides the reader with an understanding of all major instrumental analyses, and is unique in that it starts with the fundamental principles, and then develops the level of sophistication that is needed to make each method a workable tool for the student. Each chapter includes a discussion of the fundamental principles underlying each technique, detailed descriptions of the instrumentation, and a large number of applications. Each chapter includes an updated bibliography and problems, and most chapters have suggested experiments appropriate to the technique.This edition has been completely updated, revised, and expanded. The order of presentation has been changed from the 7th edition in that after the introduction to spectroscopy, UV-Vis is discussed. This order is more in keeping with the preference of most instructors. Naturally, once the fundamentals are introduced, instructors are free to change the order of presentation. Mathematics beyond algebra is kept to a minimum, but for the interested student, in this edition we provide an expanded discussion of measurement uncertainty that uses elementary calculus (although a formula approach can be used with no loss of context). Unique among all instrumental analysis texts we explicitly discuss safety, up front in Chapter 2. The presentation intentionally avoids a finger-wagging, thou-shalt-not approach in favor of a how-to discussion of good laboratory and industrial practice. It is focused on hazards (and remedies) that might be encountered in the use of instrumentation. Among the new topics introduced in this edition are:• Photoacoustic spectroscopy.• Cryogenic NMR probes and actively shielded magnets.• The nature of mixtures (in the context of separations).• Troubleshooting and leaks in high vacuum systems such as mass spectrometers.• Instrumentation laboratory safety.• Standard reference materials and standard reference data.In addition, the authors have included many instrument manufacturer's websites, which contain extensive resources. We have also included many government websites and a discussion of resources available from National Measurement Laboratories in all industrialized countries. Students are introduced to standard methods and protocols developed by regulatory agencies and consensus standards organizations in this context as well.

Medicinal Plant Responses to Stressful Conditions discusses the effects of multiple biotic and abiotic stressors on medicinal plants. It features information on biochemical, molecular and physiological strategies used to mitigate or alleviate detrimental effects of biotic and abiotic stressors. The book contains chapters featuring medicinal plants of importance covering subjects including genomics, functional genomics, metabolomics, phenomics, proteomics and transcriptomics under biotic and abiotic stress of medicinal plants and their molecular responses. It suggests exogenous application of different types of stimulants to enhance medicinal plant production in such conditions.Features: Details all aspects of biotic and abiotic stressors in various important medicinal plant species. Chapters cover evidence-based approaches in the diagnosis and management of medicinal plants under stressful conditions. Includes information on ways to mitigate effects from biotic stress (diseases and pests) or abiotic stress (high salinity, drought, temperature extremes, waterlogging, wind, high light intensity, UV radiation, heavy metals and mineral deficiencies). A volume in the Exploring Medicinal Plants series, this book is an essential resource for plant scientists, botanists, environmental scientists and anyone with an interest in herbal medicine.

The Nobel Prize is science's highest award, as is the case with non-science fields too, and it is therefore arguably the most internationally recognized award in the world. This unique set of volumes focuses on summarizing the Nobel Prize within organic chemistry, as well as the specializations within this specialty. Any reader researching the history of the field of organic chemistry will be interested in this work. Furthermore, it serves as an outstanding resource for providing a better understanding of the circumstances that led to these amazing discoveries and what has happened as a result, in the years since.An outstanding resource which enables readers to better understand the conditions that led to these Nobel Prize amazing discoveries To an extent the roots of organic chemistry have been forgotten or lost and this set of volumes bridges the gap Unique set of volumes, no other book publication in the field competes and only press releases announcing the prizes from recent years exist'More than any other branch of chemistry, organic chemists look to history, so the readers will certainly enjoy this compilation'Appeals to a diverse audience including upcoming as well as modern practicing chemists, and provides the historical context of these discoveries

This book provides a comprehensive update on recent developments of Jasmonates (JAs) and Brassinosteroids (BRs) in plant signalling and biotechnological applications. Over the last few decades, an enormous amount of research data has been generated on these two signalling molecules. This valuable compilation will enhance the basic understanding of JAs and BRs mechanism of actions ensuing tolerance mechanism of crops under climate changes for sustainable agriculture and human welfare. This book covers topics regarding the occurrence of JAs and BRs in plants, biosynthesis, role in plant growth and development, role of these PGRs during various abiotic stress tolerance in plants, crosstalk of Reactive Oxygen Species (ROS) and plant stress mitigation, regulation of JAs and BRs signaling pathways by microRNA, along with physiological and anatomical roles of JAs and BRs as wound healing, regeneration and cell fate decisions. The cross talk of JAs and BRs with neurotransmitters in plant growth and development. Bio-fortification of crop plants with BRs in managing in human health issues chapter enlightened new role of BRs in human wellbeing. This book will be beneficial to scientists, researchers, agriculturists, horticulturists, industries related to the crop and food production KEY FEATURES Reviews the global scientific literature and experimental data of the authors on the occurrence of JAs and BRs in various plants Update information on recent developments of JAs and BRs signalling and biotechnological applications in plants Highlights the physiological, metabolic and molecular mechanism of JAs and BRs under variable climates Addresses the abiotic and biotic tolerance management by JAs and BRs Describes the role of JAs and BRs in sustainable agriculture and human welfare in eco-friendly manner

Foundations of College Chemistry, 16th edition presents chemistry as a modern, vital subject and is designed to make introductory chemistry accessible to all beginning students. It is intended for students who have never taken a chemistry course or those who had a significant interruption in their studies but plan to continue with the general chemistry sequence. The central focus is to make chemistry interesting and understandable and teach students the problem-solving skills they will need. This International Adaptation offers new and updated content with improved presentation of all course material. It builds on the strengths of previous editions, including clear explanations and step-by-step problem solving. The material emphasizes real-world applications of chemistry as the authors develop the principles that form the foundation for the further study of chemistry. There is new and expanded coverage of polarizing power and polarizability – Fajans'rules, collision number and mean free path, abnormal molecular masses and van't Hoff factor, and applications of radioactivity.

Das Werden der Chemie Von den Anfängen der Untersuchung der stofflichen Welt bis zum quantitativen Verständnis chemischer Reaktionen Die Chemie als die Lehre vom Aufbau und der Umwandlung von Stoffen hat eine herausragende kulturgeschichtliche Bedeutung für die Menschheit. Es war ein langer und oft irriger Weg von der Beherrschung des Feuers über die alchemistischen Versuche, Eisen in Gold zu verwandeln, bis hin zur Chemie als exakte Naturwissenschaft, die heutzutage alle Lebensbereiche beeinflusst und durchdringt. Im ersten Teil des Buches beschreiben die Autoren die Genese der Erfassung und Ordnung der vielfältigen, in der Natur und damit auch im Alltag beobachtbaren Phänomene. Die Grundüberlegungen und Ideen dazu werden zunächst in einer allgemeinverständlichen Sprache entwickelt, ohne die oftmals verwirrende Formelsprache der Chemie und der komplexeren Mathematik. Der zweite Teil des Buches befasst sich mit den Basiskonzepten, die sich aus den gesammelten und geordneten Phänomenen entwickelt haben und diese schlüssig beschreiben. Die Autoren beschränken sich dabei auf das Wesentliche verzichten bewusst auf eine klassische Einteilung des Buches nach elementspezifischer Stoffchemie. Im Verlauf der Beschreibung der Basiskonzepte werden die Formelsprache der Chemie sowie deren mathematische Entsprechung sukzessive eingeführt.

This new 2-volume set offers a comprehensive review of more than 80 medicinal plant species, providing information on the bioactives and pharmacology of these beneficial plants. It describes the structures of the secondary metabolites found in these plants, the functions of these compounds in human and plant biology, and the biosynthesis of these compounds.Each chapter begins with a brief introduction about the species. The chapters then delve into the bioactive phytochemicals from the plant along with its chemical structure. The published literature on pharmacological activities on that species is comprehensively reviewed. A wide array of the biological activities and potential health benefits of the medicinal plant (which include antiviral, antimicrobial, antioxidant, anti-cancer, anti-inflammatory, and antidiabetic properties as well as protective effects on liver, kidney, heart and nervous system) are given.Phytochemical Composition and Pharmacy of Medicinal Plants aims to be valuable source book for scientists, researchers, industry professionals, faculty and students for the development of new and effective drugs from medicinal plants.

This book, as part of the “Natural Products Chemistry of Global Plants” series, describes in detail the health-promoting wild edible and medicinal mushrooms specific to the Himalayas region. The focus of the book is to draw on the rich culture, folklore, and environment of the Upper Himalayas, which represents a scientifically significant region. The Himalayas has rich plant resources and a large diversity of plants and mushrooms, which can provide important health benefits as detailed throughout the text. Drawing attention to these mushrooms with detailed scientific descriptions may help in the awareness and in developing sustainable growth of these important resources.Features Provides an opportunity to describe the wild edible and medicinal mushrooms from this scientifically significant region. Represents a wider variety of mushrooms than previously published in other books. Presents more content related to traditional uses, phytochemistry, pharmacology, distribution, processing, toxicology, conservation, and future prospective of individual mushrooms. The plants and mushrooms of the region are valuable resources not only to local populations but to those living outside the region. Scientists are monitoring the rich Himalayan plant resources and the consequences of climate change on this precarious ecosystem.