Search

A wide range of chemical products (especially fine chemicals) are important for a healthy and enjoyable modern life; therefore efficient syntheses of these materials are essential. Traditional stoichiometric processes need to be replaced by modern catalytical methods in the change to sustainable chemistry and the production of lower amounts of waste. This book summarizes the wide variety of catalytic methods that have been developed and applied on an industrial scale in recent years to fulfill this goal. The synthesis of compound classes such as pharmaceuticals, agrochemicals, flavoring, and fragrance compounds as well as food additives such as vitamins exemplify the use of these modern catalytic methods in the modern chemical industry.

Comprehensive Chirality, Second Edition is the definitive ten-volume reference, offering a thorough exploration of chiral research and application. This extensively updated edition features 121 new chapters and 70 revised ones, focusing on the latest advancements in chiral research across synthesis, catalysis, analytical chemistry, and bioactive compound synthesis. Edited by a world-class editorial board, with contributions from leading experts, Comprehensive Chirality, Second Edition bridges theoretical principles with practical applications, making it an invaluable resource for advanced students, researchers, and professionals. Key highlights include:- Innovative Reactions and Methods: advanced diastereo- and enantioselective techniques for controlling stereogenic centers in complex natural products and pharmaceuticals.- Chiral Auxiliaries and Modern Reagents: transformative uses of chiral auxiliaries and cutting-edge reagents such as hypervalent iodide.- Catalytic Methodologies: comprehensive coverage of C-C bond formation, emphasizing transition metals, biocatalysis, and multicatalysis.- Asymmetric Photochemistry: light-induced asymmetric transformations.- Olefin Functionalization and Cycloaddition: asymmetric oxidation and reduction methods.- Biocatalysis and Enzyme Engineering: in-depth analysis of enzyme design and engineering as powerful synthesis catalysts.- Industrial Applications: practical insights into asymmetric synthesis for industrial applications, illustrated through recent case studies.- Spectroscopic Techniques: updated spectroscopic methods for separating and analyzing enantiomers. - Unites different areas of research and allows anyone working or researching in chiral chemistry to navigate through the most essential concepts - Includes different areas of research and deep foundational reviews - Helps users apply context to diverse journal literature, aiding them in identifying areas for further research and/or for solving problems - Serves as a valuable, critical tool for instructors, practicing experimentalists, and students of the field, as well as those curious to gain appreciation of the chirality landscape and its vast expanse

This book explores some of the latest and recent advances in the synthesis, characterization and applications of magnetic nanomaterials. It starts with an overview of magnetic nanomaterials, followed by a list of their synthesis and characterization methods. The book shows the potential of magnetic materials in different applications, including theranostic nanomedicine, heavy metals detection, dyes sensing, solar cells, wastewater treatment, decontamination of soil, and detection and monitoring of toxic gases. Moreover, it explores their use as drug and gene delivery agents, their biosafety and bioregulation facets, tissue engineering applications, and their potential for combating pathogens

This fully updated second edition reflects the significant changes in process chemistry since the first edition and includes more common process issues such as safety, cost, robustness, and environmental impact. Some areas have made notable progress such as process safety, stereochemistry, new reagents and reagent surrogates. Forty years ago there were few process research and development activities in the pharmaceutical industry, partly due to the simplicity of drug molecules. With increasing structural complexity especially the introduction of chiral centers into drug molecules and stricter regulations, process R&D has become one of the critical departments for pharmaceutical companies.Features:This unique volume now in its second edition is designed to provide readers with an unprecedented strategy and approach which will help chemists and graduate students develop chemical processes in an efficient manner. Promotes an industrial mindset concerning safety and commercial viability when developing methods. The author discusses development strategies with case studies and experimental procedures. Focuses on mechanism-guided process development which provides readers with practical strategies and approaches. Addresses more common process issues such as safety, cost, robustness, and environmental impact.This book provides a new direction for scientists, researchers, and students in materials science and polymer chemistry who seek to better understand the chemistry behind conducting polymers and improve their performance for use in advanced energy applications.

This book highlights recent research and advances in natural product chemistry written by promising young researchers in this field who have played a central role for recent innovative advancements. The book consists of seventeen chapters covering novel bioactive natural products, uncovering life phenomena with natural products, biosynthesis of natural products, total synthesis of complex natural products by innovative strategies, and drug discovery using natural products. Each chapter begins with a brief and easy-to-understand introduction, then presents the cutting-edge research in each individual specialty. This book is not only a practical and essential reference resource for natural product chemists, medicinal chemists, synthetic organic chemists, biochemists, pharmacologists, as well as the pharmaceutical and biotechnological industries, but is also a useful guide to understanding new and emerging trends in this field.

In today's world, it has become necessary to shift towards a more eco-friendly and sustainable approach in the industrial field to reduce pollution and stop toxic chemicals from entering the environment. Green chemistry is an emerging concept that can be utilized to assist with these environmental issues. To ensure this concept is employed to its full potential, further study on the best practices and challenges of implementation are required. Green Chemistry for the Development of Eco-Friendly Products discusses the main objective of green chemistry and how it can redefine and modify manufacturing processes and products in order to decrease hazards to human health. The book also considers key concepts of green chemistry, such as the need to make better use of available resources for the development of a chemical process. Covering critical topics such as bioplastics, waste, and hydrogen law, this reference work is ideal for chemists, business owners, environmentalists, policymakers, academicians, scholars, researchers, practitioners, instructors, and students.

This edited book provides an in-depth overview of carbon dioxide (CO2) transformations to sustainable power technologies. It also discusses the wide scope of issues in engineering avenues, key designs, device fabrication, characterizations, various types of conversions and related topics. It includes studies focusing on the applications in catalysis, energy conversion and conversion technologies, etc. This is a unique reference guide, and one of the detailed works is on this technology. The book is the result of commitments by leading researchers from various backgrounds and expertise. The book is well structured and is an essential resource for scientists, undergraduate, postgraduate students, faculty, R&D professionals, energy chemists and industrial experts.

This book focuses on the new and old methods for the synthesis of various heterocycles using Lawesson's reagent. The book covers an important and rapidly growing branch of heterocyclic chemistry and can serve as a guide to those who are completing their education and are about to enter the job market. Students will be able to find all Lawesson's reagent-assisted protocols for the synthesis of heterocycles in one place. This feature of the book provides an important benefit, because sometimes users want to see all the possibilities and relevant information for making a particular compound using one particular reagent. The purpose of this valuable resource is to provide the knowledge not only to students but also to pharmacologists, biochemists, organic and medicinal chemists, researchers, and academic professionals for easy access to synthetic protocols for different heterocycles using Lawesson's reagent. The book will be greatly helpful for everyone involved inthe field and can pave the way for better understanding and quantification of heterocycle synthesis.

A wide range of chemical products (especially fine chemicals) are important for a healthy and enjoyable modern life; therefore efficient syntheses of these materials are essential. Traditional stoichiometric processes need to be replaced by modern catalytical methods in the change to sustainable chemistry and the production of lower amounts of waste. This book summarizes the wide variety of catalytic methods that have been developed and applied on an industrial scale in recent years to fulfill this goal. The synthesis of compound classes such as pharmaceuticals, agrochemicals, flavoring, and fragrance compounds as well as food additives such as vitamins exemplify the use of these modern catalytic methods in the modern chemical industry.

Green chemistry is a work tool that can be applied in different areas such as medicine, materials, polymers, food, organic chemistry, etc., since it was propounded in the early 2000s. It has become a viable alternative for care, remediation and protection of the environment and has been implemented worldwide. In this book the twelve principles of green chemistry are presented in a simple way, with examples of the applications of green chemistry in numerous areas showcasing it as an ideal alternative for environmental care. It also provides information on current research being implemented at the pilot plant and industrial level. The book demonstrates the importance of the use of renewable raw materials, the use of catalysis and the implementation of alternative energy sources such as the use of microwaves and ultrasound in different separation and chemical processes.

A guide to the wide-variety of waste valorisation techniques related to various biomass, waste materials and by products Waste Valorisation provides a comprehensive review of waste chemistry and its application to the generation of value-added products. The authors – noted experts on the topic – offer a clear understanding of waste diversity, drivers and policies governing its valorisation based on the location. The book provides information on the principles behind various valorisation schemes and offers a description of general treatment options with their evaluation guidelines in terms of cost, energy consumption and waste generation. Each of the book's chapters contain an introduction which summarises the current production and processing methods, yields, energy sources and other pertinent information for each specific type of waste. The authors focus on the most relevant novel technologies for value-added processing of waste streams or industrial by-products which can readily be integrated into current waste management systems. They also provide the pertinent technical, economic, social and environmental evaluations of bioconversions as future sustainable technologies in a biorefinery. This important book: Presents the most current technologies which integrate waste and/or by-product valorisation Includes discussions on end-product purity and life-cycle assessment challenges Explores relevant novel technologies for value-added processing of waste streams or industrial by-products which can be integrated into current waste management systems Offers a guide to waste reuse, a key sustainability goal for existing biorefineries wishing to reduce material and environmental costs Written for academic researchers and industrial scientists working in agricultural and food production, bioconversions and waste management professionals, Waste Valorisation is an authoritative guide to the chemistry and applications of waste materials and provides an overview of the most recent developments in the field.

Nanomaterials contain some unique properties compared to their bulk. Their unique properties are due to the chemical nature of the material, small size, and surface functionalization. Along with control over size, the functionalization of nanomaterials also affects their compatibility to the environment and living organisms. This book provides a detailed account of nanomaterials functionalization along with a brief overview of their application.This book serves as a reference for scientific investigators including doctoral and postdoctoral scholars and undergradate and graduate students who need to have knowledge of the basics of nanomaterial functionalization, recent advancements, challenges, and opportunities in this field. This book will also provide critical and comparative data for nano-technologists and may be beneficial for industry personnel, journalists, policy makers, and the general public to help understand functionalized nanomaterials in detail and in depth. Features: This book is comprehensive and covers all aspects of functionalized nanotechnology. It describes the challenges and methods of functionalized nanomaterials synthesis for different applications. It discusses the recent findings and cutting-edge global research trends on the functionalization of nanomaterials. It emphasizes the products and market, safety, and regulatory issues of functionalized nanomaterials. It contains contributions from international experts and will be a valuable resource for researchers.

This comprehensive text presents a critical discussion of the scopes and limitations of various organic synthetic methodologies that are available for performing asymmetric transformations. In addition to purely chemical methods, the book covers applications of new enzymes and other biological systems that are increasingly useful in asymmetric methodology.

The completely revised and updated, definitive resource for students and professionals in organic chemistry The revised and updated 8th edition of March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure explains the theories of organic chemistry with examples and reactions. This book is the most comprehensive resource about organic chemistry available. Readers are guided on the planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions The opening chapters of March's Advanced Organic Chemistry, 8th Edition deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Further coverage concerns general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation. The relationship between structure and reactivity is also covered. The final chapters cover the nature and scope of organic reactions and their mechanisms. This edition: Provides revised examples and citations that reflect advances in areas of organic chemistry published between 2011 and 2017 Includes appendices on the literature of organic chemistry and the classification of reactions according to the compounds prepared Instructs the reader on preparing and conducting multi-step synthetic reactions, and provides complete descriptions of each reaction The 8th edition of March's Advanced Organic Chemistry proves once again that it is a must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields.

In the fields of biologically active materials and functional materials, fluorinated organic materials are becoming a focus of significant interest. Over the past decade synthetic methodologies and reagents in fluorine chemistry have been developed, especially stereocontrolled synthetic methods, enzymatic resolution to synthesize enantiomers, fluoromethylated reagents, and fluorination reagents. These methods have contributed to the opening of new pathways for fluorinated materials. However, few fluorinated materials have been put to commercial use. Furthermore, there remain problems to be solved, such as the handling of the materials, availability of reagents and selectivity (stereo-, regio-, and/or chemoselectivity). Research chemists, technical engineers, and graduate students in all branches of chemistry, pharmaceutics, and material science interested in fluorinated materials need to know detailed experimental procedures of how to synthesize the target fluorinated materials. This volume summarizes the chemical and microbial methods for obtaining functionalized fluorinated materials for use as building blocks; detailed experimental methods (reaction conditions, solvent, temperature, handling techniques, etc.); and the stereoview (possible absolute configuration) of the structures with spectral data. Mono-, di-, tri-, and polyfluorinated materials derived from fluorinating agents, fluoromethylated reagents and building blocks are summarized. A chemical name index, molecular formula index, and reagent index are also included. The publication of this monograph will provide access to the enormous possibilities in fluorine chemistry, biological material chemistry, and functionalized material chemistry.

The literature on chlorinated biphenyl is growing rapidly. Review articles on PCB's cited in this book usually contained a section on the toxicity of PCB. The structure and nomenclature are detailed. The chapters and topics included are (1) commercial PCB preparations: properties and compositions, (2) synthesis of chlorobiphenyls, (3) chemical reactions of chlorobiphenyls, (4) photodegradation of chlorobiphenyls, (5) metabolism of chlorobiphenyls, (5) mass spectroscopy of chlorobiphenyls, (6) nuclear magnetic resonance of chlorobiphenyls, (7) ultraviolet spectroscopy of chlorobiphenyls, (8) infrared spectrometry of chlorobiphenyls, (9) determination of chlorobiphenyls, and (10) recent developments.

Encyclopedia of Interfacial Chemistry: Surface Science and Electrochemistry, Seven Volume Set summarizes current, fundamental knowledge of interfacial chemistry, bringing readers the latest developments in the field. As the chemical and physical properties and processes at solid and liquid interfaces are the scientific basis of so many technologies which enhance our lives and create new opportunities, its important to highlight how these technologies enable the design and optimization of functional materials for heterogeneous and electro-catalysts in food production, pollution control, energy conversion and storage, medical applications requiring biocompatibility, drug delivery, and more. This book provides an interdisciplinary view that lies at the intersection of these fields. - Presents fundamental knowledge of interfacial chemistry, surface science and electrochemistry and provides cutting-edge research from academics and practitioners across various fields and global regions

To fully utilize Nuclear Magnetic Resonance (NMR) spectroscopy, a comprehensive and well-organized compilation of NMR data is necessary. While compilations have been available for other important NMR nuclei, such as carbon and fluorine, no comprehensive collection of data has been prepared for phosphorus-until now. The CRC Handbook of Phosphorus-31 Nuclear Magnetic Resonance Data provides a collection of 31P NMR chemical shifts for nearly 20,000 organic and inorganic phosphorus compounds. Each class of phosphorus compound is discussed. Bond types, stereochemistry (with the exception of metal complexes), media, important coupling constants, and data sources are included. The information is systematically organized according to coordination state, the atoms bound to phosphorus, and their connectivities. A comprehensive series of bar charts is also included to allow structure types to be assigned to chemical shift data. This handbook is an invaluable resource for all scientists working with phosphorus compounds, including chemists, biochemists, medical researchers, and pharmaceutical chemists.

The Handbook for Chemical Process Research and Development focuses on developing processes for chemical and pharmaceutical industries. Forty years ago there were few process research and development activities in the pharmaceutical industry, partially due to the simplicity of the drug molecules. However, with the increasing structural complexity, especially the introduction of chiral centers into the drug molecules and strict regulations set by the EMA and FDA, process R&D has become one of the critical departments for pharmaceutical companies. This book assists with the key responsibility of process chemists to develop chemical processes for manufacturing pharmaceutical intermediates and final drug substances for clinical studies and commercial production.

The field of molecular materials research looks at the preparation and characterization of potentially useful materials with enhanced physical, chemical, and biomedical properties. Molecular Materials: Preparation, Characterization, and Applications discusses the cutting-edge interdisciplinary research in the area of advanced molecular-based materials. This book explores multiple aspects of molecular materials, including their synthesis and characterization, and gives information on their application in various fields.

Comprehensive Membrane Science and Engineering, Second Edition, Four Volume Set is an interdisciplinary and innovative reference work on membrane science and technology. Written by leading researchers and industry professionals from a range of backgrounds, chapters elaborate on recent and future developments in the field of membrane science and explore how the field has advanced since the previous edition published in 2010. Chapters are written by academics and practitioners across a variety of fields, including chemistry, chemical engineering, material science, physics, biology and food science. Each volume covers a wide spectrum of applications and advanced technologies, such as new membrane materials (e.g. thermally rearranged polymers, polymers of intrinsic microporosity and new hydrophobic fluoropolymer) and processes (e.g. reverse electrodialysis, membrane contractors, membrane crystallization, membrane condenser, membrane dryers and membrane emulsifiers) that have only recently proved their full potential for industrial application. This work covers the latest advances in membrane science, linking fundamental research with real-life practical applications using specially selected case studies of medium and large-scale membrane operations to demonstrate successes and failures with a look to future developments in the field. - Contains comprehensive, cutting-edge coverage, helping readers understand the latest theory - Offers readers a variety of perspectives on how membrane science and engineering research can be best applied in practice across a range of industries - Provides the theory behind the limits, advantages, future developments and failure expectations of local membrane operations in emerging countries

Organic Synthesis, Fourth Edition, provides a reaction-based approach to this important branch of organic chemistry. Updated and accessible, this eagerly-awaited revision offers a comprehensive foundation for graduate students coming from disparate backgrounds and knowledge levels, to provide them with critical working knowledge of basic reactions, stereochemistry and conformational principles. This reliable resource uniquely incorporates molecular modeling content, problems, and visualizations, and includes reaction examples and homework problems drawn from the latest in the current literature. In the Fourth Edition, the organization of the book has been improved to better serve students and professors and accommodate important updates in the field. The first chapter reviews basic retrosynthesis, conformations and stereochemistry. The next three chapters provide an introduction to and a review of functional group exchange reactions; these are followed by chapters reviewing protecting groups, oxidation and reduction reactions and reagents, hydroboration, selectivity in reactions. A separate chapter discusses strategies of organic synthesis, and he book then delves deeper in teaching the reactions required to actually complete a synthesis. Carbon-carbon bond formation reactions using both nucleophilic carbon reactions are presented, and then electrophilic carbon reactions, followed by pericyclic reactions and radical and carbene reactions. The important organometallic reactions have been consolidated into a single chapter. Finally, the chapter on combinatorial chemistry has been removed from the strategies chapter and placed in a separate chapter, along with valuable and forward-looking content on green organic chemistry, process chemistry and continuous flow chemistry. Throughout the text, Organic Synthesis, Fourth Edition utilizes Spartan-generated molecular models, class tested content, and useful pedagogical features to aid student study and retention, including Chapter Review Questions, and Homework Problems. A full Solutions Manual is also available online for qualified instructors, to support teaching. Winner, 2018 Textbook Excellence Award (Texty) from the Textbook and Academic Authors Association Fully revised and updated throughout, and organized into 19 chapters for a more cogent and versatile presentation of concepts Includes reaction examples taken from literature research reported between 2010-2015 Features new full-color art and new chapter content on process chemistry and green organic chemistry Offers valuable study and teaching tools, including Chapter Review Questions and Homework Problems for students; Solutions Manual for qualified course instructors

A practical handbook for chemists performing bond forming reactions, this book features useful information on the synthesis of common functional groups in organic chemistry. • Details modern functional group synthesis through carbon-heteroelement (N, O, P, S, B, halogen) bond forming reactions with a focus on operational simplicity and sustainability. • Summarizes key and recent developments – which are otherwise scattered across journal literature – into a single source• Contains over 100 detailed preparations of common functional groups• Included 25 troubleshooting guides with suggestions and potential solutions to common problems.• Complements the text in enhanced ebook editions with tutorial videos where the author provides an introduction to microwave assisted chemistry

Porous silicon is rapidly attracting increasing interest in various fields, including optoelectronics, microelectronics, photonics, medicine, chemistry, biosensing, and energy. Porous Silicon: Formation and Properties fills a gap in the literature of the field today, providing a thorough introduction to current knowledge of the formation, processin

Stresses the Potential Applications of Biosurfactants in Various IndustriesEnvironmental concerns and a demand for sustainable chemical production have become important issues in recent years. As a result, microbial biosurfactant-producing systems are gaining momentum as potential replacements for chemical surfactants. Biosurfactants: Production an

Although less common than a-amino acids, non-a-amino acids-where the amino group is not on the carbon immediately adjacent to the carboxyl group but is attached to another carbon in the chain (for example, the �, d carbon)-are components of biologically important molecules, are significant in the pharmaceutical industry, and are useful starting ma

The 3rd supplement continues the updating of the original 20 volumes on boron com­ pounds published between 1974 and 1979. The first supplement to this series brought the literature closing date uniformly to the end of 1977, whereas the two volumes of the 2nd supplement have extended the literature coverage of boron compounds to 1980. Selection and presentation of data parallel the style selected for the two previous supplement volumes, which appeared in 1980/1 and 1982/3, respectively. The Gmelin Principle of the Last Position is largely adhered to, excepting substituted polyboron species containing boron-boron bonds (all of which are found in Chapter 2 within the system boron-hydrogen). Examples of organic derivatives are included, especially in those cases where the carbon-free species are not known; and the carboranes are treated comprehensively. The literature is considered through 1984. Part 1 of the present 3rd supplement contains the systems boron-noble gases and boron­ hydrogen; Part 2 contains the system boron-oxygen. Part 3 will contain the systems boron­ nitrogen, boron-fluorine, and boron-chlorine; the remaining systems and a formula indexwill be included in the final 4th part of this supplement. The first chapter of the present volume on the compounds of boron and oxygen provides sections on the binary boron oxides, including some radicals, and the anhydrous berate ions. The following chapter describes boron-oxygen compounds with hydrogen or organyl groups.

The Handbook is part of the Handbook of Reagents for Organic Chemistry series, aiming at collecting articles on a particular theme that individual researchers in academia or industry can use on a daily basis. The Handbook starts with a section discussing the most important aspects of heteroarene functionalization. The introduction is followed by the alphabetical listing of the most relevant reagents drawn from the EROS database. The Editor, André Charette from the University of Montreal, has selected 120 reagent descriptions, many of them updated with heteroarene-specific reactions for this Handbook. Following the standard format for EROS, each article contains an overview of the synthesis and physical properties of the reagents or catalyst, conditions for its storage, and purification methods. Given the importance of heteroarenes in biology and especially in medicinal chemistry, a Handbook that focuses exclusively on heteroarene functionalization has been long overdue. This Handbook will have a broad appeal to many individuals engaged in the area of medicinal chemistry, fine chemical synthesis and industrial-scale chemistry. Key features: Builds on the success of the previously published Handbooks of Reagents for Organic Synthesis Compares the numerous new C-H functionalization reactions that have been developed in the past decade Heteroarene functionalization is widely used in the development of pharmaceuticals and other bioactive compounds Contains listings of secondary reagents for which more information is available in the online edition

The new, revised and updated 7th edition of March's Advanced Organic Chemistry clearly explains the theories and examples of organic chemistry, providing the most comprehensive resource about organic chemistry available. Readers are guided on planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions. The first five chapters deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Chapters 6 to 9 are concerned with general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation, and finally the relationship between structure and reactivity. The last 10 chapters cover the nature and the scope of organic reactions and their mechanisms. The 7th edition proves again it is a must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields. Key features of the 7th edition: Every chapter has been updated with the most recent reaction information with references to both the primary and review literature New to the 7th edition: 5,500 references since the last edition, updates / rewrites of the retained sections, and an updated index in Appendix B Contains more than 1650 reactions and 20,000 valuable references to the primary literature Includes appendices on the literature of organic chemistry and the classification of reactions according to the compounds synthesized Guides the reader on planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions. Reviews of the previous edition:'...a favorite general organic chemistry text and an easy-to-use one-volume reference. We are confident that this book will remain a dominant reference and that it will reside on many chemists'personal bookshelves.'–Journal of Medicinal Chemistry'Who can hope to be seriously accepted as a member of the organic chemistry community without being in possession of at least one edition of'March'?'–Chemistry and Industry

The increasing world population, competition for arable land and rich fishing grounds, and environmental concerns mandate that we exploit in a sustainable way the earth's available plant and animal resources for human consumption. To that end, food chemists, technologists, and nutritionists engage in a vast number of tasks related to food availability, quality, safety, nutritional value, and sensory properties—as well as those involved in processing, storage, and distribution. To assist in these functions, it is essential they have easy access to a collection of information on the myriad compounds found in foods. This is particularly true because even compounds present in minute concentrations may exert significant desirable or negative effects on foods.Includes a foreword by Zdzislaw E. Sikorski, Gdansk University of Technology, Poland; Editor of the CRC Press Chemical & Functional Properties of Food Components Series. Dictionary of Food Compounds, Second Edition is presented in a user-friendly format in both hard copy and fully searchable downloadable resources. It contains entries describing natural components of food raw materials and products as well as compounds added to foods or formed in the course of storage or processing. Each entry contains the name of the component, the chemical and physical characteristics, a description of functional properties related to food use, and nutritional and toxicological data. Ample references facilitate inquiry into more detailed information about any particular compound. Food Compounds Covered:Natural Food ConstituentsLipidsProteinsCarbohydratesFatty acidsFlavonoidsAlkaloidsFood ContaminantsMycotoxinsFood AdditivesColorantsPreservativesAntioxidantsFlavorsNutraceuticalsProbioticsDietary SupplementsVitaminsThis new edition boasts an additional 12,000 entries for a total of 41,000 compounds, including 900 enzymes found in food. No other reference work on food compounds is as complete or as comprehensive.

Brings together the best tested and proven stereoselective synthetic methods Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products. Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery. The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts: Part One: General Methods and Strategies Part Two: Stereoselective Synthesis by Bond Formation including C-C bond formation C-H bond formation C-O bond formation C-N bond formation Other C-heteroatom formation and other bond formation Part Three: Methods of Analysis and Chiral Separation References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.

Properties and applications of high surface area materials depend on interfacial phenomena, including diffusion, sorption, dissolution, solvation, surface reactions, catalysis, and phase transitions. Among the physicochemical methods that give useful information regarding these complex phenomena, nuclear magnetic resonance (NMR) spectroscopy is the

Although many books exist on the subject of chiral chemistry, they only briefly cover chiral synthesis and analysis as a minor part of a larger work, to date there are none that pull together the background information and latest advances in one comprehensive reference work. Comprehensive Chirality provides a complete overview of the field, and includes chiral research relevant to synthesis, analytic chemistry, catalysis, and pharmaceuticals. The individual chapters in each of the 9 volumes provide an in depth review and collection of references on definition, technology, applications and a guide/links to the related literature. Whether in an Academic or Corporate setting, these chapters will form an invaluable resource for advanced students/researchers new to an area and those who need further background or answers to a particular problem, particularly in the development of drugs. Chirality research today is a central theme in chemistry and biology and is growing in importance across a number of disciplinary boundaries. These studies do not always share a unique identifying factor or subject themselves to clear and concise definitions. This work unites the different areas of research and allows anyone working or researching in chiral chemistry to navigate through the most essential concepts with ease, saving them time and vastly improving their understanding. The field of chirality counts several journals that are directly and indirectly concerned with the field. There is no reference work that encompasses the entire field and unites the different areas of research through deep foundational reviews. Comprehensive Chirality fills this vacuum, and can be considered the definitive work. It will help users apply context to the diverse journal literature offering and aid them in identifying areas for further research and/or for solving problems. Chief Editors, Hisashi Yamamoto (University of Chicago) and Erick Carreira (ETH Zürich) have assembled an impressive, world-class team of Volume Editors and Contributing Authors. Each chapter has been painstakingly reviewed and checked for consistent high quality. The result is an authoritative overview which ties the literature together and provides the user with a reliable background information and citation resource.

When the Nobel Prize Committee recognized the importance of green chemistry with its 2005 Nobel Prize for Chemistry, this relatively new science came into its own. Although no concerted agreement has been reached yet about the exact content and limits of this interdisciplinary discipline, there seems to be increasing interest in environmental topic

A reactions oriented course is a staple of most graduate organic programs, and synthesis is taught either as a part of that course or as a special topic. Ideally, the incoming student is an organic major, who has a good working knowledge of basic reactions, stereochemistry and conformational principles. In fact, however, many (often most) of the students in a first year graduate level organic course have deficiencies in their undergraduate work, are not organic majors and are not synthetically inclined. To save students much time catching up this text provides a reliable and readily available source for background material that will enable all graduate students to reach the same high level of proficiency in organic chemistry. Produced over many years with extensive feedback from students taking an organic chemistry course this book provides a reaction based approach. The first two chapters provide an introduction to functional groups; these are followed by chapters reviewing basic organic transformations (e.g. oxidation, reduction). The book then looks at carbon-carbon bond formation reactions and ways to'disconnect'a bigger molecule into simpler building blocks. Most chapters include an extensive list of questions to test the reader's understanding. There is also a new chapter outlining full retrosynthetic analyses of complex molecules which highlights common problems made by scientists. The book is intended for graduate and postgraduate students, scientific researchers in chemistry - New publisher, new edition; extensively updated and corrected - Over 950 new references with more than 6100 references in total - Over 600 new reactions and figures replaced or updated - Over 300 new homework problems from the current literature to provide nearly 800 problems to test reader understanding of the key principles

This book differs from other organic chemistry textbooks in that it is not focused purely on the needs of students studying premed, but rather for all students studying organic chemistry. It directs the reader to question present assumptions rather than to accept what is told, so the second chapter is largely devoted to spectroscopy (rather than finding it much later on as with most current organic chemistry textbooks). Additionally, after an introduction to spectroscopy, thermodynamics and kinetics, the presentation of structural information of compounds and organic families advances from hydrocarbons to alcohols to aldehydes and ketones and, finally, to carboxylic acids.

Since their first industrial use polymers have gained a tremendous success. The two volumes of'Polymers - Opportunities and Risks'elaborate on both their potentials and on the impact on the environment arising from their production and applications. Volume 11'Polymers - Opportunities and Risks I: General and Environmental Aspects'is dedicated to the basics of the engineering of polymers – always with a view to possible environmental implications. Topics include: materials, processing, designing, surfaces, the utilization phase, recycling, and depositing. Volume 12'Polymers - Opportunities and Risks II: Sustainability, Product Design and Processing'highlights raw materials and renewable polymers, sustainability, additives for manufacture and processing, melt modification, biodegradation, adhesive technologies, and solar applications. All contributions were written by leading experts with substantial practical experience in their fields. They are an invaluable source of information not only for scientists, but also for environmental managers and decision makers.

While some of the most commonly investigated- and most notorious- chemicals in the world are alkaloids, many modern medicines are also based on alkaloid structures. Chemists continue to explore new synthetic routes and alkaloid derivatives in search of drug candidates for fighting disease. Drawn from the venerable Dictionary of Natural Products, th

Used in the production of a wide number of fine chemicals and pharmaceuticals, the Friedel-Crafts acylation reaction represents a synthetic process of great interest to organic chemists of academia and industry. Nearly 40 years since the last major treatise on the topic and reflecting the growing emphasis on green technology, Advances in Friedel-Cr

Surfactants play a variety of critical roles in tribology. In addition to controlling friction and wear, they also allow for control of a wide range of properties of lubricants, such as emulsification/demulsification, bioresistance, oxidation resistance, and rust/corrosion prevention. This book explains recent advances in the role of surfactants wi

The first of its kind, this dictionary defines more than 25,000 marine- natural products. It indexes each by chemical name, organism type, and compound type. Following a similar format to the Chapman & Hall Chemical Database, each entry includes biological source, chemical structure, physical properties, biological activity, and literature references. With an accompanying CD, this invaluable tool offers immediate access to information essential to the development of novel pharmaceuticals, pesticides, and marine anti-fouling agents derived from unique molecular structures of marine natural products.

Almost all branches of chemistry and material science now interface with organometallic chemistry--the study of compounds containing carbon-metal bonds. This widely acclaimed serial contains authoritative reviews that address all aspects of organometallic chemistry, a field that has expanded enormously since the publication of Volume 1 in 1964. - Fully updated and expanded to reflect recent advances - Illustrated with pertinenet examples from recent literature - Contributions from leading authorities and industry experts

Surfactants play a critical role in tribology as they control friction, wear, and lubricant properties such as emulsification, demulsification, bioresistance, oxidation resistance, rust prevention, and corrosion resistance. The use of surfactants in tribology is a critical topic for scientists and engineers who are developing new materials and devi

In this book, expert authors describe advanced solar photon conversion approaches that promise highly efficient photovoltaic and photoelectrochemical cells with sophisticated architectures on the one hand, and plastic photovoltaic coatings that are inexpensive enough to be disposable on the other. Their leitmotifs include light-induced exciton generation, junction architectures that lead to efficient exciton dissociation, and charge collection by percolation through mesoscale phases. Photocatalysis is closely related to photoelectrochemistry, and the fundamentals of both disciplines are covered in this volume.

While acid-base indicators continue to find new applications in an ever-widening range of scientific disciplines, there is no current book that focuses entirely on the subject, nor one that brings together the relevant advances that have evolved over the last three decades. The Handbook of Acid-Base Indicators compiles the most up-to-date, c

I don't have my name on anything that I don't really do. –Heidi Klum Can the organic chemists associated with so-called “Named Reactions” make the same claim as supermodel Heidi Klum? Many scholars of chemistry do not hesi- te to point out that the names associated with “name reactions” are often not the actual inventors. For instance, the Arndt-Eistert reaction has nothing to do with either Arndt or Eistert, Pummerer did not discover the “Pummerer” rearran- ment, and even the famous Birch reduction owes its initial discovery to someone named Charles Wooster (first reported in a DuPont patent). The list goes on and on… But does that mean we should ignore, boycott, or outlaw “named reac- ons”? Absolutely not. The above examples are merely exceptions to the rule. In fact, the chemists associated with name reactions are typically the original dis- verers, contribute greatly to its general use, and/or are the first to popularize the transformation. Regardless of the controversial history underlying certain named reactions, it is the students of organic chemistry who benefit the most from the - taloging of reactions by name. Indeed, it is with education in mind that Dr. Jack Li has masterfully brought the chemical community the latest edition of Name Reactions. It is clear why this beautiful treatise has rapidly become a bestseller within the chemical community.

Because enzyme-catalyzed reactions exhibit higher enantioselectivity, regioselectivity, substrate specificity, and stability, they require mild conditions to react while prompting higher reaction efficiency and product yields. Biocatalysis in the Pharmaceutical and Biotechnology Industries examines the use of catalysts to produce fine chemic

Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.

Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued.