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Basic Principles in Nucleic Acid Chemistry, Volume I provides information pertinent to the fundamental aspects of nucleic acids. This book discusses the development of the basic principles in nucleic acid research that will serve as a foundation for further advancement in nucleic acid research. Organized into six chapters, this volume begins with an overview of the history of the scientific study of nucleic acid as a genetic material. This text then examines the utility of the analogs of the naturally occurring nucleic acid components as biochemical tools and as therapeutic agents. Other chapters consider mass spectrometry that deals with the production and chemistry of ions in the vapor phase. This book discusses as well the various aspects of the excited states of the nucleic acids. The final chapter deals with the systematic study of the physiochemical properties of the monomeric units of nucleic acid. This book is a valuable resource for molecular biologists, scientists, and research workers.

Keine ausführliche Beschreibung für'1957, I. Halbjahr 1: Januar – Juni'verfügbar.

XXIIIrd International Congress of Pure and Applied Chemistry, Volume 1 compiles lectures presented in Boston, USA on July 26-30, 1971. This book is organized into three main topics: application of quantum mechanics to organic reaction paths; intramolecular rearrangements, valence isomerization, and cyclo-addition; and photochemistry. This publication specifically discusses the quantitative SCF MO studies of reaction mechanisms, interaction of particular orbitals in chemical reactions, and potential surfaces for the addition reactions of?-systems. The ring opening reactions of aziridines and oxiranes, mechanism in the system of dimers of butadiene, and thermal cyclisation of unsaturated carbonyl compounds are also elaborated. This text likewise covers the low temperature photochemistry of organic compounds, photochemical modification of biologically significant compounds, and photochemistry of thioketones. This compilation is useful to chemists and specialists working in the field of pure and applied chemistry.

Glucuronic Acid Free and Combined: Chemistry, Biochemistry, Pharmacology, and Medicine focuses on the study of glucuronic acid, particularly its physiological role in different fields. Divided into three parts with nine chapters, the book contains the literature of authors who have incessantly conducted research on this kind of acid. The book starts with the discussion on the chemistry of free glucuronic acid and its derivatives, and then discusses the nature, characteristics, and properties of glucuronides and other known conjugates. The next part presents the occurrence and chemistry of glucuronic acid incorporated in animal, plant, and bacterial polysaccharides. This presentation is followed by the discussions on the biosynthesis of glucuronic acid as UDPglucuronic acid and its relationship with simple glucuronides. A summary of information of the enzymic hydrolysis of conjugates is then presented. The succeeding chapters deal with the entry of glucuronic acid into general carbohydrate metabolism; the incorporation of glucuronic acid with the polysaccharides of living tissues; the pharmacological implications of glucuronic acid in drug detoxification; and the isolation and identification of steroid glucuronides. The book is a primary source of data for readers interested in studying the nature, composition, functions, and uses of glucuronic acid.

Advances in Clinical Chemistry

A Manual of Paper Chromatography and Paper Electrophoresis provides a comprehensive discussion of the techniques of paper chromatography and paper electrophoresis. The book is organized into two parts. Part I on paper chromatography provides a readily accessible source for some of the many uses and adaptations of paper chromatography. An effort has been made to write a practical manual in which tried and proved procedures, employing relatively simple equipment and available reagents, are summarized. Part II on paper electrophoresis discusses basic principles and methodology. The emphasis throughout has been on the separation of protein mixtures, particularly blood serum. This reflects the fact that it is in this particular application that paper electrophoresis has thus far not been challenged by paper chromatography, whereas many of the smaller molecules can be resolved equally well or better by the thus far more widely employed chromatographic procedures.