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This volume presents recent biotechnological advances in the application of extremophiles in sustainable agricultural production, plant health and soil remediation. It highlights the physiology and biochemistry of extremophiles to ensure their survival and adaptation under stressful agricultural conditions, as well as their ecological diversity and taxonomical attributes that allow them to be useful in improving abiotic and biotic tolerance among crops. The chapters cover genomic, metagenomic and metabolomic approaches for improving crop production, biocontrol, nutrient solubilization and soil health to ensure food and nutrition security in a sustainable manner in difficult growing environments. The book will be useful for students and researchers studying soil and plant management, sustainable agriculture, microbiology and biochemistry.

This book comprehensively covers critically investigated information on medicinal plants prioritized for their anti-allergy properties. It offers insights into strategies related to the distribution, mechanism of action, and assessment of antiallergic medicinal plants, and also delves into crucial aspects of modern biotechnological tools, addressing their implementation challenges, presenting innovative approaches through case studies, and exploring opportunities for nanotechnologies. These elaborated discussions aim to raise awareness and bridge the gap between human health and the biodiversity of antiallergic medicinal plants. As the book navigates the uncertainties of plant-based medicines in the post-COVID-19 era, it provides real-world applications showcasing the specific utility of medicinal plants through advanced biotechnological insights. This book covers several medicinal plants associated with antiallergy, exploring their modes of action, available secondary metabolites,and estimation methods. It also emphasizes all modern biotechnological interventions aimed at propagating, multiplying, and conserving this unique treasure trove of medicinal plants. The World Health Organization estimated that 80% of the populations of developing countries rely on traditional medicines, mostly plant drugs, for their primary health care needs. Increasing demand in both developing and developed countries resulted in the expanding trade of medicinal plants and has serious implications for the survival of several plant species, with many under threat of becoming extinct. This book describes various approaches to conserving these genetic resources. It discusses the whole spectrum of biotechnological tools from micro-propagation for large-scale multiplication and cell-culture techniques to the biosynthesis and enhancement of pharmaceutical compounds in plants. It also discusses the genetic transformation as well as short- to long-term conservation of plant genetic resources via synthetic seed production and cryopreservation, respectively. This reference book is useful for researchers in the pharmaceutical and biotechnological industries, medicinal chemists, biochemists, botanists, molecular biologists, academicians, students as well as allergic patients, traditional medicine practitioners, scientists in medicinal and aromatic plants, and other traditional medical practitioners.

This book highlights the potential of biomass for cosmetics applications. It covers the discussion on biomass as a source for cosmetics from savanna, marine and tropical forest, trend and market outlook of biobased cosmetics, active substances from biomass for cosmetics, extractives from biomass for cosmetics, other non-wood forest products such as essential oil, tengkawang, and bee pollen. Besides that, the potency of biopolymers such as lignin, and polysaccharides are presented. The book also discusses activated carbon as a cosmetic source. To present more comprehensive information, it covers biomass as anti-aging, anti-acne, sunscreen, anti-melanin, and antimicrobial. Regarding the close contact system with the human in daily life, cosmetic needs to comply with the human system. Therefore, one special chapter is dedicated to presenting the compatibility view of biobased cosmetics in the human body system. Nanomaterials in cosmetics have started to be used by many beauty companies asindicated by nano-related patents. The nanotechnology applications in cosmetics also provide future trends in bio-based cosmetics. Some forms of nanomaterials that have been reported include liposomes, nanoemulsion, nanocapsules, solid lipid nanoparticles, nanocrystals, nano-silver, nano-gold, hydrogel, etc. Iodinated Aloe Vera formulations within polymeric complexes present examples of bio-antimicrobials and such compounds are at the crossroads between pharmaceutics and cosmetics. Finally, the environmental and safety impacts of biobased cosmetic development are discussed as the closure in the last chapter.This book is expected to provide insightful information for those dealing with biomass or doing research on biomass for sustainable living. Moreover, it is also suitable for policymakers to get the new and latest information on valorizing local biomass while expanding its usage for cosmeceutical purposes. Due to the current environmental problems occurring in our surroundings, this book is seen to be an important tool to spread awareness of the smart way of utilizing our precious biomass and transforming it into valuable products.

Due to complex phytochemical components and associated beneficial properties, numerous medicinal and aromatic plants, in whole or parts, have been used for nutritional purposes or the treatment of various diseases and disorders in humans and animals. Essential oils from medicinal and aromatic plants (MAPs) have been exploited for product formulations of pharmaceuticals, cosmetics, food and beverage, colorants, biopesticides, and several other utility chemicals of industrial importance. There is scientific evidence of many medicinal plant extracts possessing immunomodulatory, immunostimulatory, antidiabetic, anticarcinogenic, antimicrobial, and antioxidant properties, thus demonstrating their traditional use in popular medicine. With the advent of modern technology, the exploitation of natural resources has exponentially increased in order to fulfill the demand of an increased human population with improved quality of life. The traditional agriculture and production-based supply of commodities is inadequate to meet the current demand. Biotechnological approaches are gaining importance to bridge the gaps in demand and supply. In the proposed book, medicinal and aromatic plant-based secondary metabolites have been discussed in terms of their therapeutic potential and industrial relevance. To discuss the qualitative and quantitative analysis of a range of medicinal and aromatic plants-based secondary metabolites (SMs), bioprocess development for their extraction and bioseparation, a brief overview of their industrial relevance, various tissue culturing strategies, biotechnological approaches to enhance production, scale-up strategies, management of residual biomass post extraction of target SMs is central to the idea of the proposed book. A section will explore the verticals mentioned above. In the next section, the book addresses the approaches for conserving and improving medicinal and aromatic plant genetic resources. In the third section, approaches to managing the post-harvest crop residue and secondary metabolites extracted plant biomass will be thoroughly discussed. The recent integration of artificial intelligence to improve medicinal and aromatic plant research at several levels, including the development and employment of computational approaches to enhance secondary metabolite production, tissue culture, drug design and discovery, and disease treatment, will be included in the fourth section. The book summarizes current research status, gaps in knowledge, agro-industrial potential, waste or residual plant biomass management, conservation strategies, and computational approaches in the area of medicinal and aromatic plants with an aim to translate biotechnological interventions into reality.

This compendium presents comprehensive information on more than 25 important spice crops commercially grown in India and traded globally, apart from over 40 spices that have the potential to be popularized. In 70 chapters the book covers the achievements in research and development made in India for the past 75 years in various organizations including research institutes, agricultural universities and private sector laboratories. Spices are natural products of plant origin, used primarily for flavouring and seasoning or for adding pungency and flavour to foods and beverages. The flavour and fragrance of Indian spices had a magic spell on human culture since very ancient days. The importance of spices in Indian life and its contribution to the economy are substantial. India, as the world's leading producer of spices is also a significant stakeholder in spices export trade globally. Indian spices being sources of many high value compounds, are also gaining muchimportance for other diversified uses especially for their pharmaceutical and nutraceutical properties. A wide variety of 52 spices are grown in India including black pepper, chillies, cardamom, ginger, turmeric, cinnamon, nutmeg, garlic, onion, cumin, coriander, saffron and vanilla. This book complies a comprehensive, holistic review on the subject, written by the best experts in the field in India representing diverse agencies. This book is a single point reference book for all those involved in the research, study, teaching and use of spices in India and abroad.

Biorationals or biopesticides are pest control agents of biological origin. Biopesticides are emerging alternatives to harmful chemical pest control agents. The book provides essential information on botanical, biological originated insecticidal, herbicidal, fungicidal, nematicidal agents, insect growth hormones, insect pheromones and plant growth regulators. It will help researchers and students to develop new strategies for pest management.

This book serves as an excellent comprehensive material covering the current understandings and updates on antimicrobial resistance (AMR) and the use of medicinal plant resources for tackling it. Chapters cover important aspects of AMR and strategies to address this threatening issue with medicinal plants and their resources. One health perspectives for addressing AMR have been presented for the readers. Antimicrobial medicinal plant therapeutic resources including crude extracts, active fractions, pure molecules and essential oils, besides using them as functionalizing agents for nano-antimicrobials have been covered. Further, plant endophytes as a source of antimicrobial compounds have been discussed. Chapters cover both the bactericidal as well as resistance-reversal (or potentiating/ combinatorial therapies) potencies of medicinal plant resources. The book also focuses on how medicinal plant resources effectively target major determinants of AMR. Use of metabolomics in understanding and targeting AMR mechanisms and identifying potent phyto-therapeutics has been discussed as well. The book is a valuable read for both experienced and younger researchers working in the field of AMR and related fields in biomedicine, pharmacy, and clinical research.

Novel Formulations and Future Trends, Volume Three in the Recent and Future Trends in Pharmaceutics series, explores aspects of pharmaceutics with an original approach focused on technology, novelties and future trends. It discusses the most important developments in drug delivery, including important and exciting areas such as mucosal, implantable, transdermal, gastroretentive, vaccine and targeted drug delivery systems. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. This is an essential reference for researchers in academia and industry as well as advanced graduate students. New technologies are also explored including 3D printing and computational pharmaceutics. - Explores the most recent technologies in drug delivery in detail - Contains contributions from the leading experts from academia, research, industry and regulatory agencies - Includes high quality illustrations, flow charts and tables for easy understanding of concepts - Discusses practical examples and research case studies

This book delves into antibiotic resistance, offering insights into its emergence, mechanisms, and impact on global health. The book also scrutinizes over-prescription, agricultural use, and the scarcity of new drug development, while spotlighting the role of globalization in its propagation. It moves beyond conventional approaches, examining alternative strategies like phage therapy, immunotherapy, and nanotechnology. Highlighting precision diagnostics and the importance of policy implications, it navigates through public health strategies, surveillance, and international collaborations. Finally, it glimpses into the future, delineating the challenges, opportunities, and the urgency of action required to steer away from a post-antibiotic era. This book serves as an invaluable resource for students, researchers, and scientists in the fields of medicine, pharmacy, microbiology, and public health.

This book describes recent important advancements in nanobiotechnology for biomedical applications as well as explaining fundamentals and examining potential applications in biomedical settings. Nanobiotechnology is the study of applications of nanotechnologies in biological or biomedical settings. It is an interdisciplinary field of growing importance whose subcategories encompass chemical engineering, molecular biophysics, and cellular mechanics or tissue engineering. This book is structured in a way to summarize the latest process in nanobiotechnology at the molecular, cellular, tissue, and organ levels. The principles of the underlying science are presented, and widely accepted applications in the field and newly designed techniques are extensively described. Fresh insights are provided into the convergence of science and technology. This book is an ideal guide to the field that will be of value especially for researchers from interdisciplinary fields and higher level graduate students with extraordinary inspirations and research training.

This book provides new insight and a better understanding of nanotechnology in mitigating crop biotic stresses.It covers crop diseases and different nano-based management strategies used to manage pathogens and plant-parasitic nematodes damaging crops. Nanoparticles have the potential to revolutionize crop yield and can control plant biotic stress. Nanotechnology in plant pathology is a new frontier among various nanotechnological applications. Nanotechnology applications include the development of nano-based pesticides and nanoformulations of chemicals for crop improvement by reducing biotic stress. Different nanomaterials like ZnONPs, SiO2NPs, CuONPs, AgNPs, and TiO2NPs have been examined for their impacts on plant growth and biotic stress management. This book deals with the advanced use of nanotechnology in managing the biotic stress of crops and improving crop production. It covers these issues and many more. Each chapter focus on one particular topic. Incorporate chapters provide detailed information on nanotechnology and may help in future research. This book will be useful for researchers, professors, and postgraduate and undergraduate students, especially concerning agriculture and plant pathology.

The book explains the use of natural products as scaffolds in tissue engineering. It presents an introduction to the concept of natural product-based scaffolds and explores various fabrication strategies for their synthesis. The book highlights the wide range of applications of these scaffolds in tissue engineering, including their use in tissue regeneration, wound healing, plastic surgery, and breast reconstruction. Specific natural products, such as gums (xanthan, gellan, arabic, guar, ghatti gum), chitosan, collagen are discussed in separate chapters. In addition, various application of natural product loaded PCL and PLA scaffolds have also been discussed. Each chapter focuses on the application of these natural product based scaffolds and explores their potential in tissue engineering. It also covers specific applications of these scaffolds in tissue regeneration, including angiogenesis, bone, skin, and nerve tissue regeneration. The book addresses important considerations regarding the toxicity and regulatory aspects of natural product-based scaffolds and explores the challenges associated with their implementation and emphasizes the need for safety and compliance in their use. Overall, the book provides a comprehensive overview of the field. It serves as a valuable resource for researchers, scientists, and professionals in the field of tissue engineering.

Emerging Methods for Oil Extraction from Food Processing Waste is a comprehensive and cutting-edge exploration of sustainable oil extraction practices, catering to professionals and researchers in food science. The book, spanning 13 insightful chapters, intricately reviews the extraction of oil from food processing by-products, including pomace and surplus raw materials. It specifically focuses on emerging non-thermal technologies, offering valuable insights into improving oil extraction rates. The discussions encompass factors influencing extraction rates and suggest processing conditions based on various extraction methods and raw materials. In addition to providing a nuanced understanding of conventional and novel extraction techniques, the text delves into the diverse applications of the extracted oil, ranging from food preservation to fortification and fat replacement. Notably, it covers advanced processing techniques for enhancing oil stability, bioavailability, and bioactivity through emulsion and encapsulation methods. Addressing crucial commercial aspects, the text explores economic feasibility, safety considerations, and consumer acceptability, providing a holistic perspective for successful industrial adaptation. Authored by global specialists, each chapter offers in-depth scientific reports and critical analyses, making this volume an indispensable resource for continuous research and advancement in the dynamic field of food processing.

Medicinal Biotechnology: Methods and Applications covers a wide range of topics from traditional herbal medicine to recent plant and animal biotechnology approaches used for the production of vaccines, hormones, enzymes, edible medicinal products, herbal therapeutics, and other secondary metabolites. The book opens with a historical perspective of medicinal biotechnology which includes a discussion of successive development in the field of medicine, starting from early civilization up to current and advanced approaches and strategies. The book also provides a wide range of topics that include: a discussion engineering approaches in medicinal biotechnology, metabolomics, extraction of metabolites, personalization approaches, and strategies for the effective use of medicinal product and drugs; explanation of engineering approaches in medicinal biotechnology, metabolomics, extraction of metabolites, personalization approaches, and strategies for the effective use of medicinal product and drug; and coverage of specific knowledge on the production and use in vaccines, antibodies, and hormones. - Provides a discussion of the traditional medicine system and the role of herbs - Discusses plant and animal tissues culture/engineering approaches used to produce medicinal products such as vaccines, antibiotics, and hormones - Highlights the discussion of topics related to DNA profiling, genome editing, synthetic biology, bioprospecting, metabolomics, personalized medicine, and intellectual property rights in relation to the medicinal product - Emphasizes the therapeutic potential of edible plant products and herbal therapeutics for chronic disease management

The book explores the world of medicinal plants through a groundbreaking and comprehensive book. It delves into high-throughput technologies and multi-omics approaches to unlock the untapped potential of endophytic fungi, revealing novel bioactive compounds. It further talks about the diverse biodiversity and ethnopharmacological knowledge, unravelling the molecular intricacies of secondary metabolites under varying ecological conditions. This gives insights into medicinal plant research, offering cutting-edge insights into genome-based barcoding, nanotechnology, and functional genomics for revolutionary drug discoveries. From proteomic and epigenomic analysis to big data exploration, this book presents a holistic view of medicinal plants'potential and discusses the latest advancements in micropropagation, agronomical approaches, and genome editing, paving the way for transformative medicines and healthcare breakthroughs.It serves as a great resource for academicians, researchers, and pharmacologists.

This book explains the translational aspects of ethnomedicinal plants of different geographical regions including India by explaining the medicinal properties against several diseases, genomic evolution in changing environments, metabolic profiling for biomarker discovery, the role of non-coding RNA in the synthesis of secondary metabolites, genome-wide transcriptome profiling, application of pluripotent stem cells for drug discovery, the importance of high-throughput omics, and genome-editing techniques. In addition, some of the chapters have been designed to describe the role of artificial intelligence, plant database, and network-based drug discovery to explore the medicinal importance of compounds as well as challenges and opportunities in drug discovery from ethnomedicinal plants. The book serves as a great source of information for the students, researchers/scientists of diverse fields such as pharmacognosy, plant physiologists, biotechnologists, and pharmaceutical scientists etc., working in the areas of phytotherapy from ethnomedicinal plants.

This book offers a comprehensive and authoritative review of the key environmental areas and compartments where fragrances have been found and discusses the current challenges of their presence and potential hazards. The book starts with a chapter devoted to the manufacturing and characterization of the most relevant types of fragrances, and their emissions to the environment. Subsequent chapters cover topics such as fragrances'toxic effects on the environment, their major routes of exposure, behaviour, and fate in different environmental matrices. Particular attention is given to ecotoxicological issues and the environmental impact of fragrances in wastewater treatment plants, surface waters, marine environments, soils, remote areas, and air. In this book, readers will find valuable insights into the bioaccessibility and availability of synthetic musks in seafood and the corresponding human exposure and health risks. The book also outlines the most promising analytical methods used for fragrance detection and quantification, and it discusses the risks and future trends in this field. Written by a multidisciplinary team of expert contributors, and considering its scope, this book is an essential tool not only for scholars and researchers in academia and industry but also for other stakeholders and decision-makers interested in the field of fragrances and their ecotoxicology, as well as environmental impacts.

This concise text on biologically active substances of the food, pharmaceutical and agricultural industries presents data on natural compounds of vegetable and animal origin. Various nutrients in food, phytochemicals and zoochemicals are discussed, including their uses for prophylactic, metaphylactic and therapeutic purposes in personalized medicine. Along with these compounds, prebiotics isolated by biotechnological methods from plant tissues are reviewed, with the aim of obtaining compounds with an oligoglucide structure. Metabolism of nutrients and the biodegradation of xenobiotics are hot topics and access routes into the human body for the various biologically active substances are covered.Features: Biologically active substances and related chemistry, biochemistry and agrochemistry data are rigorously discussed Data regarding natural compounds of vegetable origin detected from plants present in the spontaneous flora and plants obtained in agricultural crops (medicinal plants, aromatic plants and more) are presented Discusses the natural compounds of animal origin detected in the organisms of some terrestrial and aquatic animals Covers prebiotics isolated by technological and biotechnological methods from plant tissues, with the aim of obtaining compounds with oligoglucide structure Broad audience including all those in biochemistry, the food and pharmaceutical industries and agricultural fields

This contributed volume provides a comprehensive, in-depth and subject-based reviews on the current status of active ingredients, sustainable use, biodiversity and conservation of certain endangered medicinal plants. The book also explores conventional and non-conventional biotechnological interventions for their biodiversity conservation. Medicinal plants have been used in worldwide as a major source of raw material for the traditional herbal healthcare practices as well as for drug discovery and development in pharmaceutical industry. The cumulative consequences of various human activities and environmental factors cause decline in the biodiversity of medicinal plants at an unprecedented rate worldwide. Thus, the overall understanding of ecology, species and genetic diversity along with assessment of the status of different threats and their impact on medicinal plants is crucial to sustain existing biodiversity, its utilization and conservation. All the latest advancements in the biotechnological approaches for the conservation research of endangered medicinal plants and the future perspectives have been described. This book provides comprehensive reviews spreading over about 25 chapters divided in three sections. The chapters of this book are written by recognized scientists in their respective fields which are useful to students, academicians, researchers, botanists, biotechnologists, policy makers, conservationists and industries interested in biodiversity conservation and medicinal plant research for the production of secondary metabolites.

Nanotechnology is gaining importance in every field of science and technology. Green synthesis of nanomaterials involves the use of microorganisms such as bacteria, fungi, viruses; and different lower and higher plants. Green synthesis of nanomaterials from plant extracts becoming popular in comparison to synthesis using microorganisms. Plant based-nanomaterials synthesis is easy, have no need to bring back from the culture medium, and is safe. Additionally, plant-based nanomaterials are eco-friendly, in comparison to physical and chemical modes of synthesis. Several lower and higher plants are rich in terms of secondary metabolites. These metabolites have been used as medicine in crude extract form or with some other formulations. They have been also used to isolate the bioactive compounds in modern medicine as well as in herbal medicine systems. Thus, phytochemicals present in the plant and their parts play an important role in nanomaterials synthesis, mainly due to the presence of a significant number of secondary metabolites, for instance, alkaloids, flavonoids, saponins, steroids, tannins, etc. Further, essential and aromatic oils have been also explored for nanomaterials synthesis, and they are also equally useful in terms of their various biological applications. These organic ingredients come from a wide range of plant components, such as leaves, stems, roots, shoots, flowers, bark, and seeds. Globally, the presence of different plants has shown a capability to produce huge and diverse groups of secondary metabolites. The functional groups present in the plant extract acts as capping and stabilizing agent. Most of the time, pure isolated bioactive compounds are more biologically active; hence scholars are focusing their research on the synthesis of nanomaterials using some particular class of secondary metabolites. Investigations have shown that the green synthesized nanomaterials were found to be more biologically active in comparison to chemicallysynthesized nanomaterials. These nanomaterials and or nanocomposites found different applications especially in drug delivery, detection and cure of cancer cells, diagnosis of a genetic disorder, photoimaging, and angiogenesis detection. They have also shown several applications in agricultural, horticultural as well as forestry sectors. The book in hand covers a wide range of topics as mentioned above. It incorporates chapters that the authors have skilfully crafted with clarity and precision, reviewing up-to-date literature with lucid illustrations. The book would cater to the need of graduate students as a textbook and simultaneously be useful for both novices and experienced scientists and or researchers working in the discipline of nanotechnology, nanomedicine, medicinal plants, plant science, economic botany, chemistry, biotechnology, pharmacognosy, pharmaceuticals, industrial chemistry, and many other interdisciplinary subjects. It should also inspire industrialists and policy makers associated with plant-based nano products.

This contributed volume brings out a comprehensive collection of changes from cellular to molecular levels in medicinal plants under extreme environments. The focus of this book is to address the molecular changes in medicinal plants under different abiotic stresses. Medicinal plants are regarded as rich resources of components that can be used for drug development in the pharmaceutical industry. A few medicinal plants are considered vital sources of nutrients and solicited for their therapeutic properties. Therefore, it is essential to understand medicinal plants'interaction under abiotic stresses as compounds obtained from these plants play an important role in human health. This book is of interest to students, teachers, researchers, scientists, medicinal plant experts, and policymakers. Also, the book provides study material for undergraduate and graduate students of botany, environmental sciences, medicinal and aromatic plants, biochemistry, and biotechnology. National and international scientists working in the area of medicinal plants, drug development, and policymakers will also find this a useful read

Bioorganic and Enzymatic Catalysis Direct comparison of enzymatic reactions and corresponding catalytic transformations in the laboratory Bioorganic and Enzymatic Catalysis covers the most important enzymatic reactions and related catalytic bioorganic reactions using a new approach: Each enzymatic reaction type is compared with organocatalytic, organometallic and other alternative reactions, allowing the reader to understand catalytic reactions in a much-integrated way. For example, in a chapter that describes aldolases corresponding reactions using catalytic antibodies, organocatalytic reagents and metal complexes are discussed. Written by a well-known expert in the field with more than 30 years of experience in organic and bioorganic chemistry, Bioorganic and Enzymatic Catalysis covers sample topics such as: Enzymatic C-C bond formation using aldolases Claisen-type C-C bond formation involving fatty acid synthases and polyketide synthases Biomimetic cyclisations involving carbenium ions Enzymatic oxidation and C-H activation Dioxygenases and oxidoreductases With its unique approach, Bioorganic and Enzymatic Catalysis is a valuable source of information for professionals and researchers in academia and industry as well as graduate and PhD students working in the fields of organic chemistry, biochemistry, and life sciences.

Natural resources and associated biological diversity provide the basis of livelihood for humans, particularly in rural areas and mountain regions around the world. Over centuries, indigenous peoples, traditional societies and local communities have developed their own specific knowledge regarding plant use, management, and conservation. The history of plant use by humans as food and to treat diverse ailments dates back to ancient civilizations. Even though the advent of allopathic medicine has somehow minimized the role of medicinal plants in favor of synthetic drugs, a number of modern drug discoveries have been based on medicinal plants used by indigenous peoples. Ethnobiology is the burgeoning interdisciplinary scientific field which covers all sorts of interactions between plants and people, and Central Asia is recognized as a plant diversity hot spot. The mountains and valleys of this region are rich in unique medicinal and food plant species. Local communities residing in the mountain regions of Central Asia possess unique knowledge of surrounding resources, which is the result of many years of interaction with and selection of the most desirable and pervasive plant species present. In this context, this book provides comprehensive information on cross-culture variation in the traditional uses of plants, fungi, and animal species as food, medicine, and for cultural purposes among the diverse communities of Uzbekistan. The key areas of focus include plant diversity in Uzbekistan, cross cultural variation in traditional uses of plant species, high-value medicinal and food plant species, and threats and conservation status of plant species and traditional knowledge

The book provides an overview relevant to various biological mechanisms that regulate carbon exchanges between the major components and their response to climate change. Climate change has a significant impact on people's lives, energy demand, food security, etc. The soil microbial ecology is vital for assessing terrestrial and aquatic carbon cycles and climate feedback. However, the primary concern is the complexity of the soil microbial community and its severely affected functions due to the climate and other global changes. Global warming comprises an assessment of the dynamic interactions and feedback between microbes, plants, and their physical environment due to climate change. The book will address the need to use a multifactor experimental approach to understand how soil microorganisms and their activities adapt to climate change and the implications of carbon cycle feedback. The most pressing concern is a clearer understanding of the biological factors that regulate carbon exchanges between land, oceans, and the atmosphere and how these exchanges will respond to climate change via climate–ecosystem feedbacks, which could augment or quell regional and global climate change. Terrestrial ecosystems play an important role in climate feedback as they produce and absorb greenhouse gases like carbon dioxide, methane, and nitrous oxides. They also strongly contribute to storing enormous amounts of carbon in living vegetation and soils, rendering them a significant global carbon sink. If climate change projections are realistic, such a rapid increase in carbon loss from soil could exacerbate the soil carbon cycle feedback. The book will determine the role of microbial feedback in regulating soil-land-atmosphere carbon exchange under changing climatic conditions at the regional and global levels. The current book will also focus on recent research designed to use beneficial microbes such as plant growth-promoting microorganisms, fungi, endophytic microbes, and others to improve understanding of the interaction and their potential role in promoting advanced management for sustainable agricultural solutions. Understanding the influence on the native microbiome, such as the distribution of methanogens and methanotrophs, nutritional content, microbial biomass, and other factors, is becoming increasingly crucial to establishing climate-resilient agriculture.

This volume discusses the nutraceutical importance, production technologies, management and cultivation practices of underutilized vegetables, which can be described as those vegetable crops which are neither grown commercially on a large scale nor traded widely. While much of the crops addressed in the book are cultivated, traded and consumed at the local level, there are over 60 species of minor vegetables with high growth and yield potentials that are not cultivated to a large extent for greater populations. This work highlights the production technologies needed to grow these vegetables on a larger scale and under various adverse soil and climatic conditions, and their nutritional and medical benefits to assist with food security, health and poverty alleviation in rural areas. Production of underutilized vegetables is low, due to the unavailability of planting material, lack of awareness about the nutritional and medicinal importance among the farmers and inadequateinformation on the production techniques of these crops. In this context, there is an urgent need to take up a program on genetic resources exploration, management, utilization, and improvement of underutilized vegetable crops to ensure food and nutritional security. Readers will learn about these technologies and practices, while also learning about the unique properties and benefits of these underutilized vegetables. The book will be useful for academicians and researchers focusing on vegetable production and breeding, as well as farmers and sustainability scientists looking for underexplored sources of nutrition to benefit large rural populations.

Plant mycobiome represents a diverse array of plant-associated communities of endophytic and epiphytic fungi. These communities fundamentally affect plant health, development, adaptation, and communication with the surrounding ecosystem. Furthermore, they have key roles in the establishment, diversification, productivity, and sustainability of different natural ecosystems. However, some of these communities are pathogenic for the plant itself or dangerous for the consumers, due to the production of mycotoxins. In other words, plant mycobiome represents two faces of a coin. This book aimed to explore contributions of the plant mycobiome in plant-environment interactions from different perspectives. Chapters of this book address numerous themes covering the recent advances in roles, diversity, and dynamics of these fungi as biocontrol agents, biofertilizers, growth promoters, and their secondary metabolites in the area of crop improvement for sustainability and biotechnology, aswell as the plant pathogenic and toxigenic fungi. This book will be useful to postgraduate students, botanists, mycologists, ecologists, plant pathologists, and physiologists.

This book is a comprehensive collection of information on essential oils and their industrial application. It provides reader with a systematic and advanced knowledge of the role of essential oils as natural preservatives and therapeutic agents. Food and pharmaceuticals are two important pillars of human civilization. Plant essential oils and their volatile compounds have been used for preservation as well as for the treatment of human illness for long as traditional practices in biodiversity-rich countries. This book deals with the potential uses of essential oils against insect pests and spoilage microbes of agri-food commodities such as pulses, cereal, fruits, and their shelved products. It also highlights the molecular-assisted engineering of plant essential oils, the pharma-kinetic facet, and their potential in pharmaceutical and aromatherapy. In addition, the book covers recent advances in science and technology such as extraction methods, metabolomics, phytochemical genomics, bioinformatics, conformational dynamics, mathematical modeling, and nanotechnology application. This book is of interest to teachers, researchers, food scientists, capacity builders, and policymakers. Also, it serves as an additional reading material for undergraduate and postgraduate students of agriculture, food, and pharmaceutical sciences.

Under ongoing climate change, natural and cultivated habitats of major food crops are being continuously disturbed. Such condition accelerates to impose stress effects like abiotic and biotic stressors. Drought, salinity, flood, cold, heat, heavy metals, metalloids, oxidants, irradiation etc. are important abiotic stresses; and diseases and infections caused by plant pathogens viz. fungal agents, bacteria and viruses are major biotic stresses. As a result, these harsh environments affect crop productivity and its biology in multiple complex paradigms. As stresses become the limiting factors for agricultural productivity and exert detrimental role on growth and yield of the crops, scientists and researchers are challenged to maintain global food security for a rising world population.This two-volume work highlights the fast-moving agricultural research on crop improvement through the stress mitigation strategies, with specific focuses on crop biology and their response to climatic instabilities. Together with'Climate Resilient Agriculture, Vol 2: Agro-Biotechnological Advancement for Crop Production', it covers a wide range of topics under environmental challenges, agronomy and agriculture processes, and biotechnological approaches, uniquely suitable for scientists, researchers and students working in the fields of agriculture, plant science, environmental biology and biotechnology.

Under ongoing climate change, natural and cultivated habitats of major food crops are being continuously disturbed. Such condition accelerates to impose stress effects like abiotic and biotic stressors. Drought, salinity, flood, cold, heat, heavy metals, metalloids, oxidants, irradiation etc. are important abiotic stresses; and diseases and infections caused by plant pathogens viz. fungal agents, bacteria and viruses are major biotic stresses. As a result, these harsh environments affect crop productivity and its biology in multiple complex paradigms. As stresses become the limiting factors for agricultural productivity and exert detrimental role on growth and yield of the crops, scientists and researchers are challenged to maintain global food security for a rising world population.This two-volume work highlights the fast-moving agricultural research on crop improvement through the stress mitigation strategies, with specific focuses on crop biology and their response to climatic instabilities. Together with'Climate Resilient Agriculture, Vol 1: Crop Responses and Agroecological Perspectives', it covers a wide range of topics under environmental challenges, agronomy and agriculture processes, and biotechnological approaches, uniquely suitable for scientists, researchers and students working in the fields of agriculture, plant science, environmental biology and biotechnology.

This book Introduces the extensive applications of metabolomics from all possible areas of research and development so that not only an undergraduate can understand the advancement of metabolomics, but an entrepreneur can harness the knowledge to address possible problems to make a perfect tool to address their research question. Topics covered include the role of metabolomics in the development of agriculture, plant pathology, and their applications; the generalized application of the metabolomics and use of related technologies in various sectors of industries; and the future of metabolomics and upcoming related technologies that can fill the gap between different -omics and their applications for the betterment of humankind. This is an ideal book for university professors, researchers, and advanced-level scientists who are exploring different avenues in metabolomics. Availability of this concise information in one place will aid scientists by expanding their arsenal of techniques and can be helpful to bring more collaborations and to identify the expert at the global level.

Research in recent years has increasingly shifted away from purely academic research, and into applied aspects of the discipline, including climate change research, conservation, and sustainable development. It has by now widely been recognized that “traditional” knowledge is always in flux and adapting to a quickly changing environment. Trends of globalization, especially the globalization of plant markets, have greatly influenced how plant resources are managed nowadays. While ethnobotanical studies are now available from many regions of the world, no comprehensive encyclopedic series focusing on the worlds mountain regions is available in the market. Scholars in plant sciences worldwide will be interested in this website and its dynamic content. The field (and thus the market) of ethnobotany and ethnopharmacology has grown considerably in recent years. Student interest is on the rise, attendance at professional conferences has grown steadily, and the number of professionals calling themselves ethnobotanists has increased significantly (the various societies (Society for Economic Botany, International Society of Ethnopharmacology, Society of Ethnobiology, International Society for Ethnobiology, and many regional and national societies in the field currently have thousands of members). Growth has been most robust in BRIC countries.The objective of this new MRW on Ethnobotany of Mountain Regions is to take advantage of the increasing international interest and scholarship in the field of mountain research. We anticipate including the best and latest research on a full range of descriptive, methodological, theoretical, and applied research on the most important plants for each region. Each contribution will be scientifically rigorous and contribute to the overall field of study.

This contributed volume deals with problems associated with huge biomass generated by crop plants and the processing of fruits and food materials. The main focus is to address problems associated with organic residues from agro-industrial processes. This book aims to provide a comprehensive and up-to-date account of various processes involved in the valorization of this huge biomass available from agro-industrial processes and obtaining valuable primary and secondary metabolites which will have an impact on the rural economy. Decrease in forest cover associated with the production of agriculture-based waste resulting in pollutants like smoke by burning of residual crops, waste from breweries, food processing, pruning of bushes and trees, and from industries producing proteins, vegetable oils and fruit juices etc.This book is of interest to teachers, researchers, climate change scientists, agriculture scientists and policymakers. The book brings out the latest reading material for botanists, biotechnologists, environmentalists, biologists, policymakers and NGOs working for environmental protection.

This book provides a comprehensive overview of medicinal plants and their interaction with abiotic stress in terms of morphological, physiological, biochemical, and molecular variations, and explains the adaptation and tolerance mechanisms involved. It presents various mechanisms that become operative in medicinal plants to combat stressful situations. The book discusses the secondary metabolites and/or bioactive compounds produced in medicinal plants under abiotic stress conditions, and the use of biostimulants and/or phytoprotectants to alleviate the adverse effects of abiotic stresses on medicinal plants. Additionally, it is likely to address opportunities and challenges in molecular and omics studies of medicinal plants under abiotic stress conditions. Overall, the chapters are developed by eminent subject experts with due care and clarity and cover an up-to-date literature review with relevant illustrations. The book would cater to the need of graduate and post-graduate students, researchers as well as scientists, and may attract the attention of pharmaceutical companies/industrialists and health policymakers.

This book presents a complete overview of COVID-19 and provides a series of in-depth analyses of the literature and a comprehensive discussion and perspectives on promising anti-SARS-CoV-2 agents based on the system of ethnopharmacology, which covers Chinese medicine, traditional medicines of India and Africa, Turkish folk medicine, essential oils, and some well-known medicinal plants. In this book, the current status of therapeutic strategies against COVID-19 was summarized and a perspective of potential options for the future was proposed. Based on ethnopharmacology, some well-established traditional herbal formulations and bioactive compounds with anti-virus activity were repurposed for managing COVID-19 and post-illness, including neurological disorders and kidney illness. Using drug discovery tools, promising immune enhancers were explored from phytochemicals against SARS-CoV-2. Nutraceuticals from dietary plants, spices, and fruits with anti-virus and antioxidant activities were recommended to prevent infection or severe illness caused by emerging variants. With the aid of systems pharmacology, researchers have gained insights into possible molecular mechanisms of anti-SARS-CoV-2 activity and have predicted a range of candidate compounds from medicinal plants to combat COVID-19. This book explores the current knowledge of drug discovery and ethnopharmacology for managing coronavirus diseases. The content proved the anti-SARS-CoV-2 activity from natural products and traditional herbal medicines. It contributes to the management of global public health and fits the goal of establishing “Good Health and Well-Being,” which is one of “The Sustainable Development Goals (SDGs) 2030'.

Drying of Aromatic Plant Material for Natural Perfumes provides readers with a deep understanding of the fascinating world of aromatic plants, drying, extraction and perfumery. It covers the significance and global demand of essential oils, a glimpse of plant histology, secretion and storage of secondary metabolites in plant tissues, drying technologies and selection for dehydration of herbage, extraction, chemical compositions and applications. The book is organized into four sections: plant cell structures and their role during dehydration, aromatic plants and their essential oil contents, composition and contribution towards perfumery, and dehydration and extraction technologies. The book does the following: Summarizes commercially important aromatic plant materials and extracted essential oil around the world and their socio-commercial impact Includes structures of plant tissues, inherent mass transfer pathways, along with the presence and role of water, the understanding of which can aid dehydration and extraction Describes methods for selecting drying parameters and relates drying mechanisms with microstructure Discusses drying technologies for heat-sensitive materials and extraction technologies for selective component extractions Covers preprocessing, extraction and standardization of essential oils for blending for different applications This book serves as a handy tool for R&D, industrial, and academic researchers working in perfumery, fragrance, and food science, as well as chemical and agricultural engineering.

Drying is a key operation in processing of many plant-based foods and medicines for the purpose of preservation and retention of key attributes and active compounds. Therefore, it is essential to select suitable drying techniques to ensure a product is processed under optimal operating conditions. Drying of Herbs, Spices, and Medicinal Plants presents processing aspects of these three major global agricultural commodities. It offers an insight into the drying and product quality of herbs, spices, and medicinal plants, such as drying characteristics, equipment selection, physiochemical analyses, quality improvement, product development, storage, and shelf life as well as future developments. Offers the latest information on drying and processing technologies, research, and development Summarizes various drying techniques, their advantages and limitations, industrial applications, and simple design methods Presents guidelines for dryer selection Links theory and practice Envisages future trends and demands Featuring chapters from expert authors in both industry and academia, this book is an important resource for those working in the chemical, food processing, pharma, and biotech industries, especially those focused on the drying of plants for food and medicinal applications.

This volume explores the quickly evolving field of Purinergic signaling, and examines how receptors for ATP and other nucleotides, and receptors for adenosine, act in neuronal transmission, control of synaptic activity, proliferation, differentiation and cell death regulation in the CNS. This book focuses on the participation of purinergic receptors and ectonucleotidases, degrading ATP into adenosine, in embryonic and adult neurogenesis in vitro and in vivo as well as in synaptic transmission and pathophysiology. Further, the chapters discuss varying brain diseases, including Parkinson's, and Alzheimer's disease, autism, mood disorders and epilepsy, as well as brain tumors, in the context of purinergic signaling and its clinical aspects. The development of purinergic receptor agonists is also an important issue of this book. This book provides a critical review of the current state of science and will be useful for both scientists and students who are or would like to get involved in this area. Furthermore, this book addresses neuroscientists, physician and professionals from the industry, who would like to update themselves in this exciting and rapidly growing field of neuroscience.

This book highlights recent advances in variety of nanomaterials classes including metal chalcogenides, metal oxides/hydroxides, polymer, metal-organic frameworks, and hybrid nanostructures, with a focus on their properties, synthesis methods, and key applications. It also offers detailed coverage on the toxicity aspects with possible solution. Additionally, it provides complete and comprehensive information on surface modification strategies of nanoparticles to achieve desired outcomes. This book discusses potential applications and major challenges of using these nanomaterials in the fields of biomedical sciences, agricultural industry, bioenergy, biofuel production, and environmental remediation, etc. Overall, this book provides crucial background in nanobiotechnology that compliments the understanding of experimental design for the production of more customized nanomaterials to avail desirable benefits.

The disability-adjusted life year (DALY) is a generic measure of health effect that can be used in cost-effectiveness analysis as an alternative to the quality-adjusted life year (QALY). Infectious diseases are one of the major to cause significant losses of DALY and QALY. Human infectious diseases are disorders that are triggered by the micro-organisms such as bacteria, fungi, viruses, or parasites. The majority of such diseases are contagious and create a public health menace. There are several reasons why infectious diseases are deadly diseases, and one of the primary reasons is the drug resistance developed over time. Drug resistance-associated mutations are linked to increasing drug efflux, modifications of the drugs, or their targets. Every year, new drugs are being approved by FDA to treat infectious diseases. Nonetheless, the infectious diseases will undoubtedly persist as permanent and main threats to humanity for now and in the future, primarily due to increased longevity that almost always comes at a cost of impaired immunity.A total of four books are covered under the series of Infectious drug diseases.- Malarial drug delivery systems- Tubercular drug delivery systems- Viral drug delivery systems- Infectious disease drug delivery systemsThe third volume of series is focused on viral drug delivery systems. Typically, virus attaches to the cells (referred as host cell) and releases its DNA or RNA inside the cell. In second stage, virus's genetic material takes control of the cell and forces it to replicate the virus leading to onset of disease symptoms. DNA class of viruses include Herpes, Papilloma and Adeno viruses. RNA class of viruses include retroviruses, such as HIV immunodeficiency virus and SARS COV – 2 / Corona virus. This book addresses recent developments in viral drug delivery systems. It covers many different aspects of viral infections, ways to treat them using modern drug delivery systems like nano particulate carriers. The choice of viral delivery systems mainly depends upon the type of virus, duration of life cycle, presence of drug resistance, cellular and mucosal interaction of virus, accordingly gene or non-gene drug delivery systems are selected. Besides that, this book also reports global dynamics of viral diseases, future predictions of infection rate, current treatment options, details of drug carriers like nanoemulsions, polymeric nanoparticles, role of biofunctionalization, and phyto-molecules in treatment of viral infections particularly herpes, Covid-19, Ebola, HIV/AIDS, influenza and viral hepatitis.Audiences from a broad range of groups, from researchers, academicians, and public health bodies to regulatory experts, can benefit from the compiled information to learn more about patient needs and current research advances in the field of viral drug delivery research.

In the twenty-first century Pharmacognosy was transformed into a molecular science building on classic botanical and modern chemical knowledge, leading to a better understanding of the complex molecular effect - structure relationships and interactions required for the development of new drugs based on biologically active plant substances.The work demonstrates the place of phytotherapy in healing, the role of herbs in complementary and traditional therapy, and research strategies for the development of drugs of natural plant origin.This book is primarily designed for scientific researchers, but is also very useful for undergraduate and postgraduate students in their professional training. As this book discusses herbs from all over the world, it is specifically drafted to be useful not only in Hungary and Europe, but also for people in other continents as an English language encyclopaedia of medicinal plants and their biologically active compounds.

This book dispenses a comprehensive coverage of up-to-date account of genomics and genome editing enriched smart plant breeding approaches for enhancing genetic gains in vegetable crops in the post-genomics era. The main focus of the present volume is to illuminate the applications of new techniques evolved in the post-genomics era. The techniques covered are high-throughput sequencing of DNA and RNA, genome editing, epigenetics and epigenomics, genotype by sequencing (GBS), QTL-seq and RNA-seq for transcriptome analysis. Vegetables are the important component of healthy diet, source of energy and hold a promising position in building up a strong immunity. Zero hunger and attaining the food and nutritional security is the top priority of United Nations development goals. Smart breeding of food and vegetable crops to fight the challenges ahead in sustainable manner by keeping the harmony with nature is an important approach to fulfill the United Nations Sustainable Development Goals (UN-SDGs). This edited book highlights the modern results in smart vegetable breeding in the post genomics era and forecasts crucial areas of future needs. It is an important reference for the, readers, students, researchers, scientists in academia and research industries to provide them comprehensive information of innovative approaches for crop improvement in the post-genomics era and in the era of and climate change. Even the readers, academia, social activists, and others fond of reading will get a fair idea of journey travelled so far and future roadmap for fighting the challenges ahead to meet the sustainable development goals.

The book is devoted to an important aspect of pharmacology and pharmaceutical chemistry, i.e. the significance of stereoisomerism of drugs for their biological effect from the point of view of their pharmacokinetics, pharmacodynamics and toxicology. The authors review the landmarks in the development of stereochemistry and stereopharmacology. Present-day IUPAC terminology is discussed; general issues of stereoisomerism are considered including separation of racemic mixtures and asymmetric synthesis of isomers, methods of quantifying the isomers of a drug in biological material. The authors put special emphasis on general problems of the influence of stereoisomerism on pharmacological and adverse effects of drugs. A classification of drugs based on stereochemical properties of their isomers is proposed. Possibilities of interaction of stereoisomers in racemic mixtures are discussed. A considerable portion of the book is devoted to pharmacological action of the main groups of drugs whose structure includes asymmetric atoms (that is, drugs with several isomers). Detailed attention is paid to advisability of developing single isomer drugs and to the specifics of their study at the stage of preclinical and clinical trials.

This book discusses inorganic/metallic nanopesticides and fertilizers. Rather than providing a general review of the topic, it offers a critical assessment of what has been achieved and highlights future measures to allow agriculture to profit from the properties of inorganic nanoparticles. It covers a variety of topics, including strategies for preparing cost-effective nanoparticles, their chemistry both within and outside the plant, the effects of nanoparticles in the field and whether the current strategies were successful in increasing crop yields. This book will appeal to readers in academia and industry, as well as stakeholders and anyone who has an interest in the applications of inorganic nanopesticides and nanofertilizers as well as the potential use of these technologies in agriculture.

This book covers sustainable recycling processes (e.g. physical, biological, chemical, and thermo-chemical) of multiple organic solid wastes, provides methods for material recycle of wastes into value-added products including fuels and commodity chemicals that are able to be directly applied to promote manufacturing processes. Aimed at improving the awareness of effective conversion protocols and for developing innovative biomass conversion processes, this text was conceived as a collection of studies on state-of-art techniques and know-how for production of biofuels and chemicals from sustainable recycling of organic solid wastes. Topics in the text are discussed in terms of addressing recent advances, assessing and highlighting promising new methods or new technological strategies and direct conversion of organic solid wastes to process feeds. Highly-recognized authorities, experts and professionals have contributed individual chapters in selected areas to cover the overall topic in a comprehensive manner.

This book compiles the latest information on different kinds of natural, plant-based super sweeteners. A book on alternative, natural super sweeteners is extremely timely and useful, especially, in light of the decreasing cultivable area, ever increasing demand for sucrose, and the well identified ills of sugar consumption. Every year more than 5.0 million people die due to diabetes and diabetes-associated diseases like cardiovascular, kidney disorder, liver cancer etc. This book describes the use of non-saccharide super sweet principles to counter such maladies. The readers will get an in-depth understanding of different kinds of sweeteners, molecular basis of sweetness, their general classification, plant source with photo-plates etc. The chapters explain different kinds of super-sweet principles. This book emphasizes on the propagation, cultivation and conservation of NSSS plants (NSSSP) and extraction of super sweet principles and granting of generally recognised as safe (GRAS) certificate to sweeteners. The concluding chapter describes the eco-physiological difference between saccharide super sweet and non saccharide sweet plants. The book also describes commercial production of selected potential Natural Super Sweeteners. This book will be of great interest to researchers, extension workers as well as postgraduate students in Food science nutrition, ayurveda, plant physiology, Unani, naturopathy, biochemistry and plant breeding. It would also be of interest to industry stakeholders in sweetener industry and alternative sweetener manufactures.

Bioenhancers have been used in Ayurveda historically and are now being investigated for their pharmacological effi cacy. Herbal bioenhancers work on the gastrointestinal tract to improve absorption and drug bioavailability by acting on the drug metabolic process. Many herbal drugs show low activity due to their poor lipid solubility or improper molecular size. Piperine, gingerol, naringin, quercetin, niaziridin, glycyrrhizin, allicin, curcumin, genistein and others are able to enhance the bioavailability of active pharmaceuticals. This book details various facets of herbal bio-enhancers in a single comprehensive text.

Plant secondary metabolites are plant-based natural products that display a variety of pharmacological effects. This book discusses the invaluable bioactivity and multifaceted potential of these compounds. The book describes the physico-chemical and biochemical aspects of the plant secondary metabolites along with the chemistry, therapeutics and future perspectives of these plant secondary metabolites. Moreover, the book also discusses about various sources of plant secondary metabolites, and the metabolite determination through various analytical techniques. It further describes the potential applications of plant secondary metabolites as anticancer and chemo preventive agents, their role as cosmetic ingredients and activity in skin cancer therapy. Further chapters emphasize upon the plethora of roles of plant secondary metabolites, including those as antivirals, anti-bacterial, anti-inflammatory drugs, cardioprotective agents etc. The book culminates with chapters on the impact of certain plant secondary metabolites in plant defence and human healthcare. This book is meant for researchers and students in the field of pharmacology and plant sciences. Moreover, this book is also useful for industry experts especially working in the field of herbal therapeutics.

This book covers recent advances and future trends in yeast synthetic biology, providing readers with an overview of computational and engineering tools, and giving insight on important applications. Yeasts are one of the most attractive microbial cell factories for the production of a wide range of valuable products, including pharmaceuticals, nutraceuticals, cosmetics, agrochemicals and biofuels. Synthetic biology tools have been developed to improve the metabolic engineering of yeasts in a faster and more reliable manner. Today, these tools are used to make synthetic pathways and rewiring metabolism even more efficient, producing products at high titer, rate, and yield. Split into two parts, the book opens with an introduction to rational metabolic pathway prediction and design using computational tools and their applications for yeast systems and synthetic biology. Then, it focuses on the construction and assembly of standardized biobricks for synthetic pathway engineering in yeasts, yeast cell engineering and whole cell yeast-based biosensors. The second part covers applications of synthetic biology to produce diverse and attractive products by some well-known yeasts. Given its interdisciplinary scope, the book offers a valuable asset for students, researchers and engineers working in biotechnology, applied microbiology, metabolic engineering and synthetic biology.