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Synthetic biology is enabling scientists to use engineered genetic circuits in the cells as the basis for the development of new living therapeutics and as a powerful new weapon in the fight against diseases, especially cancer. Bacteria-mediated therapy is a promising alternative cancer treatment. The book covers the recent developments of cellular therapies from a synthetic biology perspective including engineered microbial therapies, CAR-T therapies etc. and is an indispensable guide to scientists in both biotechnology and medicine.

Nanosensors in Healthcare Diagnostics examines the role of nanosensors in clinical microbiology, point-of-care sensing, clinical diagnostics, and therapy.This book addresses the concept of nanosensors and their utilization in healthcare diagnostics, and therapy. It covers the principles and mechanisms involved in nanosensor-based diagnostics platforms. It also discusses various approaches and techniques used in the preparation of nanosensors as well as the biomedical application of nanosensors in clinical diagnostics and their significance in the detection, treatment, and management of diseases. This book is a useful reference for researchers, graduate students, and industry professionals studying nanosensors in biological and medical sciences.• Brings together multiple perspectives, in-depth analyses, and insights on nanosensors and its application in disease diagnostics and therapy• Covers the basic aspects of functioning principles and discusses the technologies and challenges of present and future analytical sensing approaches for diagnosis and treatment• Outlines the significant types of nanosensor platforms explored and developed for efficient detection

This Volume 2 of a two-volume work provides an up-to-date overview of the latest advances in live biotherapeutics research, engineered and genome-edited probiotics. It focuses on key areas within probiotics and microbiome studies in human medicine, including their translation into commercial applications. The book is divided into three sections, comprising (I) biomedical and nutritional benefits of probiotics for human health, (II) post-genomic technologies in probiotics sciences and genome engineering, and (III) biosafety aspects and prospects of biotherapeutics. The broad spectrum of industry-relevant contributions makes this work a valuable resource for industry professionals as well as researchers in functional food and feed biotechnology, applied microbiology and gastroenterology. Presenting novel and evidence-based research, this volume will drive the commercial enterprise and meets the great demand for good probiotic products in the human medical sector.

Nanoscience or the science of the very small offers the pharmaceutical scientist a wealth of opportunities. By fabricating at the nanoscale, it is possible to exert unprecedented control on drug activity. This textbook will showcase a variety of nanosystems working from their design and construction to their application in the field of drug delivery. The book is intended for graduate students in drug delivery, physical and polymer chemistry, and applied pharmaceutical sciences courses that involve fundamental nanoscience. The purpose of the text is to present physicochemical and biomedical properties of synthetic polymers with an emphasis on their application in polymer therapeutics i.e., pharmaceutical nanosystems, drug delivery and biological performance. There are two main objectives of this text. The first is to provide advanced graduate students with knowledge of the principles of nanosystems and polymer science including synthesis, structure, and characterization of solution and solid state properties. The second is to describe the fundamentals of therapeutic applications of polymers in drug delivery, targeting, response modifiers as well as regulatory issues. The courses, often listed as Advanced Drug Delivery and Applied Pharmaceutics; Polymer Therapeutics; or Nanomedicine, are designed as an overview of the field specifically for graduate students in the Department of Pharmaceutical Sciences Graduate Programs. However, the course content may also be of interest for graduate students in related biomedical research programs. These courses generally include a discussion of the major principles of polymer science and fundamental concepts of application of polymers as modern therapeutics. All courses are moving away from the above mentioned course names and going by ‘pharmaceutical nanoscience or nanosystems'. This area of research and technology development has attracted tremendous attention during the last twodecades and it is expected that it will continue to grow in importance. However, the area is just emerging and courses are limited but they are offered.

This book provides a comprehensive review of nanomaterials, including essential foundational examples of nanosensors, smart nanomaterials, nanopolymers, and nanotubes. Chapters cover their synthesis and characteristics, production methods, and applications, with specific sections exploring nanoelectronics and electro-optic nanotechnology, nanostructures, and nanodevices. This book is a valuable resource for interdisciplinary researchers who want to learn more about the synthesis of nanomaterials and how they are used in different types of energy storage devices, including supercapacitors, batteries, fuel cells solar cells in addition to electrical, chemical, and biomedical engineering.Key Features: Comprehensive overview of how nanomaterials can be utilised in a variety of interdisciplinary applications Explores the fundamental theories, alongside their electrochemical mechanisms and computation Discusses recent developments in electrode designing based on nanomaterials, separators, and the fabrication of advanced devices and their performances

This edited book deals with the distribution, classification and diversity of halophytic ecosystems, ecology of mangroves, coastal agroforestry, adaptations and mechanisms of salt tolerance in glycophytes verses halophytes, scope of biosaline agriculture, and potential utilization of halophytes in abiotic stressed environments in arid and semiarid regions and coastal areas. In this era of global population increase and global environmental change, there is need to provide food to the ever-growing population, combating climate change and conserving biodiversity. Keeping in view the rich biodiversity of halophytes, there is wide scope in food industry, phytoremediation, as well as a source of bioactive compounds including modern drugs. The new technologies for the cultivation of halophytes help to utilize saline and arid wastelands and also waterlogged areas sustainably for humans and the livestock. This book creates interest in educationists, researchers, industrialists, investors, soil and climate change scientists, development/extension workers, environmentalists, policy/decision makers, and government and non-government organizations. Also, the book serves as reference material for undergraduate and graduate students of agriculture, ecology, soil science, and environmental sciences. National and international soil and agricultural scientists, ecologists, policy makers will also find this book immensely useful.

This book offers a comprehensive and authoritative review of the key environmental areas and compartments where fragrances have been found and discusses the current challenges of their presence and potential hazards. The book starts with a chapter devoted to the manufacturing and characterization of the most relevant types of fragrances, and their emissions to the environment. Subsequent chapters cover topics such as fragrances'toxic effects on the environment, their major routes of exposure, behaviour, and fate in different environmental matrices. Particular attention is given to ecotoxicological issues and the environmental impact of fragrances in wastewater treatment plants, surface waters, marine environments, soils, remote areas, and air. In this book, readers will find valuable insights into the bioaccessibility and availability of synthetic musks in seafood and the corresponding human exposure and health risks. The book also outlines the most promising analytical methods used for fragrance detection and quantification, and it discusses the risks and future trends in this field. Written by a multidisciplinary team of expert contributors, and considering its scope, this book is an essential tool not only for scholars and researchers in academia and industry but also for other stakeholders and decision-makers interested in the field of fragrances and their ecotoxicology, as well as environmental impacts.

A comprehensive and multidisciplinary guide to nanomaterials-based medicine Nanomedicine is the study and application of nanomaterials-based medical techniques. In recent years it has very rapidly become indispensable in a huge range of medical contexts, from analysis of extreme life events to diagnosis and treatment of life-threatening intractable diseases, such as cancers and cardiovascular diseases. It has already transformed both research and clinical outcomes in many areas of medicine and promises to continue as the cutting-edge research and clinical area for the next generation of medical specialists. Nanomedicine: Fundamentals, Synthesis, and Applications constitutes a comprehensive guide to this subfield and its recent advances. Beginning with a brief history of the field and introduction to its core principles, it thoroughly treats recent developments in this vital and ever-growing field. Its multidisciplinary approach equips the reader with a systematic overview of these life-saving developments in medicine. Nanomedicine readers will also find: Edited by a leading researcher with decades of experience in both North America and ChinaDetailed treatment of subjects including nanocarriers, nanomaterial bioprobes, multi-function nanodrugs, nanomedicine-mediated immunotherapy and/or physical ablation, and moreA comprehensive volume treats every facet of the subject Nanomedicine is a vital resource for biochemists, biomedical engineers, pharmaceutical chemists, physicists, and professionals in the biotechnological industries, as well as for clinicians looking to familiarize themselves with nanomedical techniques and instrumentation.

This book provides an updated account of recent advancements in the field of nanotechnology-based theranostics with special emphasis on their application in the diagnosis and treatment of various types of cancer and neurological diseases. The book is divided into two sections; the first section provides an introduction to the nanoscale theranostics & radiopharmaceuticals. The second section highlights the importance of nanoscale theranostics in disease diagnosis & treatment. It presents the potential of nanotechnology for developing nanomedicine and nanotheranostics for the diagnosis and treatment of a variety of illnesses. Further, the book discusses the usefulness of theranostic nanoparticles in the diagnosis of disease, identification of location, and stage, and in providing information about the therapy response. In addition, the book focuses on the clinical applications of nanomaterial radiolabeling in nuclear imaging of cancer and other illness. Towards the end, the bookexamines the toxicity, regulatory protocols, and future aspects of clinical applications of theranostics. This book is an invaluable source for academicians and industrial scientists working in multiple healthcare fields like pharmaceutical and biological sciences, life sciences, biotechnology, biomedical engineering, and nanobiotechnology. ​

Recent years have seen a sharp rise in novel resistant pathogenic microorganisms. Bioprospecting, or the systematic identification, evaluation and exploitation of the diversity of life in a certain place, is a means of mining microorganisms for what is known as exploitable biology, or valuable genetic information. This information can then be used in the development of novel antibiotics, enzymes, food sources, and energy sources, all of which are of pressing industrial interest across agricultural, nutraceutical, pharmaceutical, biomedical and bioenergetic fields. Microbe-derived bioactive compounds are currently of significant use to the development of sustainable approaches in environmental protection efforts. However, production challenges currently pose a barrier to the large-scale commercialization of microbe-derived products. Bioprospecting of Microbial Resources for Agriculture, Environment and Bio-Chemical Industry is a much-needed review of the current achievements and emerging challenges facing the field of microbe-derived compound production. It covers established knowledge while also proposing solutions to various limitations,and introducing the application of microbe-based products in pollution control and the development of greener technologies. As the preservation of global biodiversity and the production of novel antibiotics are both of significant importance to researchers and the general public alike, this text offers a timely and comprehensive look into the many uses of microbial products across industries. Specific uses covered in the text include the microbial-based recovery of metals for e-waste, the use of microbial nanowires in bioenergy applications, and omics-based technologies in bioprospecting.Through a comprehensive investigation into the current and emerging research on microbial bioprospecting, this text will expand possibilities for the application of microbial resources nutraceutical, pharmaceutical, biomedical and bioenergetic fields. It offers valuable insights for administrators, policy makers, and consultants. It is also a helpful guide for researchers and students in the areas of microbiology, microbial prospecting, food and plant biotechnology, industrial microbiology, biochemical engineering and environmental science.

This book highlights the potential of biomass for cosmetics applications. It covers the discussion on biomass as a source for cosmetics from savanna, marine and tropical forest, trend and market outlook of biobased cosmetics, active substances from biomass for cosmetics, extractives from biomass for cosmetics, other non-wood forest products such as essential oil, tengkawang, and bee pollen. Besides that, the potency of biopolymers such as lignin, and polysaccharides are presented. The book also discusses activated carbon as a cosmetic source. To present more comprehensive information, it covers biomass as anti-aging, anti-acne, sunscreen, anti-melanin, and antimicrobial. Regarding the close contact system with the human in daily life, cosmetic needs to comply with the human system. Therefore, one special chapter is dedicated to presenting the compatibility view of biobased cosmetics in the human body system. Nanomaterials in cosmetics have started to be used by many beauty companies asindicated by nano-related patents. The nanotechnology applications in cosmetics also provide future trends in bio-based cosmetics. Some forms of nanomaterials that have been reported include liposomes, nanoemulsion, nanocapsules, solid lipid nanoparticles, nanocrystals, nano-silver, nano-gold, hydrogel, etc. Iodinated Aloe Vera formulations within polymeric complexes present examples of bio-antimicrobials and such compounds are at the crossroads between pharmaceutics and cosmetics. Finally, the environmental and safety impacts of biobased cosmetic development are discussed as the closure in the last chapter.This book is expected to provide insightful information for those dealing with biomass or doing research on biomass for sustainable living. Moreover, it is also suitable for policymakers to get the new and latest information on valorizing local biomass while expanding its usage for cosmeceutical purposes. Due to the current environmental problems occurring in our surroundings, this book is seen to be an important tool to spread awareness of the smart way of utilizing our precious biomass and transforming it into valuable products.

Due to complex phytochemical components and associated beneficial properties, numerous medicinal and aromatic plants, in whole or parts, have been used for nutritional purposes or the treatment of various diseases and disorders in humans and animals. Essential oils from medicinal and aromatic plants (MAPs) have been exploited for product formulations of pharmaceuticals, cosmetics, food and beverage, colorants, biopesticides, and several other utility chemicals of industrial importance. There is scientific evidence of many medicinal plant extracts possessing immunomodulatory, immunostimulatory, antidiabetic, anticarcinogenic, antimicrobial, and antioxidant properties, thus demonstrating their traditional use in popular medicine. With the advent of modern technology, the exploitation of natural resources has exponentially increased in order to fulfill the demand of an increased human population with improved quality of life. The traditional agriculture and production-based supply of commodities is inadequate to meet the current demand. Biotechnological approaches are gaining importance to bridge the gaps in demand and supply. In the proposed book, medicinal and aromatic plant-based secondary metabolites have been discussed in terms of their therapeutic potential and industrial relevance. To discuss the qualitative and quantitative analysis of a range of medicinal and aromatic plants-based secondary metabolites (SMs), bioprocess development for their extraction and bioseparation, a brief overview of their industrial relevance, various tissue culturing strategies, biotechnological approaches to enhance production, scale-up strategies, management of residual biomass post extraction of target SMs is central to the idea of the proposed book. A section will explore the verticals mentioned above. In the next section, the book addresses the approaches for conserving and improving medicinal and aromatic plant genetic resources. In the third section, approaches to managing the post-harvest crop residue and secondary metabolites extracted plant biomass will be thoroughly discussed. The recent integration of artificial intelligence to improve medicinal and aromatic plant research at several levels, including the development and employment of computational approaches to enhance secondary metabolite production, tissue culture, drug design and discovery, and disease treatment, will be included in the fourth section. The book summarizes current research status, gaps in knowledge, agro-industrial potential, waste or residual plant biomass management, conservation strategies, and computational approaches in the area of medicinal and aromatic plants with an aim to translate biotechnological interventions into reality.

This book comprehensively covers critically investigated information on medicinal plants prioritized for their anti-allergy properties. It offers insights into strategies related to the distribution, mechanism of action, and assessment of antiallergic medicinal plants, and also delves into crucial aspects of modern biotechnological tools, addressing their implementation challenges, presenting innovative approaches through case studies, and exploring opportunities for nanotechnologies. These elaborated discussions aim to raise awareness and bridge the gap between human health and the biodiversity of antiallergic medicinal plants. As the book navigates the uncertainties of plant-based medicines in the post-COVID-19 era, it provides real-world applications showcasing the specific utility of medicinal plants through advanced biotechnological insights. This book covers several medicinal plants associated with antiallergy, exploring their modes of action, available secondary metabolites,and estimation methods. It also emphasizes all modern biotechnological interventions aimed at propagating, multiplying, and conserving this unique treasure trove of medicinal plants. The World Health Organization estimated that 80% of the populations of developing countries rely on traditional medicines, mostly plant drugs, for their primary health care needs. Increasing demand in both developing and developed countries resulted in the expanding trade of medicinal plants and has serious implications for the survival of several plant species, with many under threat of becoming extinct. This book describes various approaches to conserving these genetic resources. It discusses the whole spectrum of biotechnological tools from micro-propagation for large-scale multiplication and cell-culture techniques to the biosynthesis and enhancement of pharmaceutical compounds in plants. It also discusses the genetic transformation as well as short- to long-term conservation of plant genetic resources via synthetic seed production and cryopreservation, respectively. This reference book is useful for researchers in the pharmaceutical and biotechnological industries, medicinal chemists, biochemists, botanists, molecular biologists, academicians, students as well as allergic patients, traditional medicine practitioners, scientists in medicinal and aromatic plants, and other traditional medical practitioners.

This edited book addresses the introduction to wheat, advancements in breeding, the contribution of biotechnological approaches, the development of climate-resilient wheat cultivars, and biofortification efforts to create nutrient-rich wheat cultivars.The world faces simultaneous challenges of a growing population and climate change. It is anticipated that the world population will exceed 9 billion by 2050. Meanwhile, climate change significantly impacts agriculture through uneven patterns, expected to worsen in the coming years, resulting in substantial losses due to biotic and abiotic stresses. Wheat, a staple food for millions worldwide, requires more studies to develop climate-resilient cultivars with improved nutritional content. Given these considerations, it is crucial to understand the activities conducted for wheat breeding and address the current gap to ensure an ample food supply for future generations.This book is beneficial for researchers, teachers, agriculturists, biologists, climate change scientists, and organizations involved in wheat breeding. It also serves as a valuable resource for undergraduate, master, and PhD students interested in wheat.

Emergence of lifestyle diseases, e.g., type II diabetes, cancers, obesity, cardiovascular disorders, liver cirrhosis, etc., are exponentially increasing day by day. Modern drifts toward the utilization of herbal medicines in different healthcare aspects necessitate (demand) the replacement of synthetic molecules with phytoconstituents because of their biocompatibility, biodegradability, economic extraction process, and ready availability from the natural source. This book provides a thorough insight into the comprehensive and up-to-date trends of phytomedicines in the management of lifestyle diseases and its mechanisms, modern methods of extraction and purification of phytoconstituents, and chemical characterization as well as standardization of phytoconstituents using modern equipments.

This book provides an in-depth overview of marine greens and their environmental and biotechnological applications. It addresses concepts such as the niche adaptation strategies of marine greens in their natural habitats, as well as their global distribution, and factors affecting their distribution and proliferation.Marine greens are posited as an alternative to fossil fuels, mitigating global climate change and thereby fostering future environmental sustainability. In addition, the book explains the remediation of xenobiotics, wastewater, microplastics, marine debris and marine green contamination. Expert authors from around the world explore the industrial and agricultural applications of marine greens in the production of enzymes and marine bioenergy, and what is needed to improve its production potential.This is important reading for government and non-governmental organizations as well as industries and research institutions looking for ways to combat current industrial and environmental challenges.

This edited volume provides a comprehensive view of the recent developments on Bacillus and their application in agriculture and allied sectors in a global scenario. Research articles sharing a consolidated state-of-the-art development in this area are solicited for this book. This book is a complete package covering all spheres of diversity and taxonomy, nutrient supplementation, biotic and abiotic stress management, biofilm and endophytic colonization, commercialization and regulatory mechanisms, etc. Descriptions of cutting-edge techniques and novel approaches on Bacillus research is also covered. A part of the book concentrates on the biotic and abiotic stress management in several important crops. It contains 11 contributory chapters from eminent experts in the field of life sciences specially microbiology, plant pathology and biotechnology working on different aspects of Bacilli and their application in agriculture and allied sectors. This book is useful for Graduate, Post-graduate students, research scholars, and post doctorate scholars of plant science, plant microbiology, soil microbiology and plant pathology discipline researchers, academicians, industrialists, policy makers.

This book explores the role of nanotechnology in the delivery of natural phytoconstituents and cosmeceuticals. It presents polymeric nanocarriers, lipid-based nanocarriers, metal/metal oxide nanocarriers, protein nanocarriers, and dendrimers for the delivery of phytoconstituents. Further, it focuses on the usage of phytocompounds in various cosmeceutical products and nano delivery technologies used in the delivery of various cosmeceuticals. Finally, the book reviews the toxicity issues of nanoparticles in the delivery of phytoconstituents and cosmeceuticals and regulatory aspects for clinical applications of nano phytomedicines. This book is helpful for academicians and researchers working in pharmaceutical sciences, nano science, material science, plant science, and cosmetic science.

Microbial Biotechnology for Bioenergy presents the new and emerging biotechnological and microbiological approaches in bioenergy and their economic, social, and environmental implications. Using the latest global data and statistics, it analyses how bioenergy technology improves quality of life by reducing air and water pollution and mitigates energy dependence by creating renewable resources in local communities. The book is formed of three sections; Section 1 addresses the'Sources, Challenges, and Environmental Views of Bioenergy and includes an overview of bioenergy, global statistics and projections for future bioenergy development, the role of biotechnology and bioprocesses in bioenergy, feedstock sources, challenges, decarbonisation, and emerging innovations and technologies. Section 2'Yesterday, Today, and Tomorrow: Innovations of Bioenergy examines the vast topics of biotechnology and microbiology for bioenergy, reviewing both the present day state-of-the-art and future potential. Readers will find dedicated chapters on bioconversion of biomass energy and biological residues, the role of microbes, the potential of organic waste to provide bioenergy, the biotechnology of biofuels such as bioethanol, biodiesel, and biohydrogen, the sustainability of cellulosic ethanol energy and artificial photosynthesis, Power-to-X and integrating energy storage innovations, and the sustainability of microbial fuel cells. Finally, Section 3 explores the policies and environmental aspects of bioenergy, providing a global perspective on the current and future impact of bioenergy, including global projections based on present day global statistics. Microbial Biotechnology for Bioenergy is a valuable reference for biotechnologists, environmental engineers, and microbiologists interested in bioenergy, and includes explanations of the fundamentals and key concepts to ensure it is accessible to students as well as researchers and professionals. - Critically reviews past, present, and future bioenergy technologies, including global statistics, policies, and emerging approaches - Highlights opportunities to improve quality of life and mitigate energy dependence, reducing air/water pollution and creating renewable resources in local communities - Explores environmental benefits of incorporating microbial remediation into bioenergy production

This book focuses on the applications of plant growth promoting microorganisms (PGPMs) in the form of bioinoculants to enhance the crop productivity and resilience against pathogens. Chapters explain the latest findings on development of the bioinoculants utilizing the modern technologies and agri-wastes. It also provides the latest information on methods of improving quality and efficiency of bioformulations and utilization of advanced biotechnological tools for developing precision products. PGPMs play important roles in survival and health of the plant. These useful microorganisms provide plants with nutrients, protect them from pathogens and help in combating abiotic stresses. It is important that these mutualistic interactions between plant and soil microbes are well understood so as to develop reliable products in the form of biostimulants, biopesticides and manage biotic and abiotic stresses in crops. Apart from enhancing crop productivity, plant-microbe interactions can also perform activities such as reclamation of degraded lands, degradation of pollutants and remediation of saline or marginal lands. This book is of interest to teachers, researchers, plant scientists and microbiologists. Also, the book serves as an additional reading material for undergraduate and graduate students of agriculture, microbiology, ecology, soil science, and environmental sciences.

This book is the second edition of the one originally published in 2016, which focused on state-of-the-art microfluidic research in medical and biological applications. Similar to the first edition, beginners in the field —undergraduates, engineers, biologists, medical and pharmaceutical researchers—will easily learn to understand microfluidic-based medical and biological applications. Because a wide range of topics is summarized here, it also helps experts to learn more about fields outside their own specialties. In this second edition, significant revisions have been made to chapters covering technologies that have seen major advancements, such as acoustofluidics, protein crystallography, organ-on-a-chip systems, nanopore sensing, and paper-based microfluidics. In addition, the chapters on cancer diagnosis using exosomes and single-cell sequencing using droplet microfluidics, which are attracting attention as new technologies, have been newly added. Readers will be convinced that microfluidic devices have great potential for medical and biological applications.

From this book reader will learn the best research topics and the latest development trend in MMESE theory and application. Man-Machine-Environment System Engineering (MMESE) is a scientific study on the design concepts and quantitative analysis of a complex giant system using physiology, psychology, system engineering, computer science, environment science, management theory, education, and other related disciplines methods. MMESE focuses mainly on the relationship and the optimum combination between Man, Machine, and Environment. The three optimized goals of the MMESE study are safety, efficiency, and economy. Researchers and professionals who study a human-centered interdisciplinary subject crossing above disciplines will be mostly benefited from this proceedings. In 1981 with direct support from one of the greatest modern Chinese scientists, Xuesen Qian, Man-Machine-Environment System Engineering (MMESE), the integrated and advanced science research topic was established in China by Professor Shengzhao Long. Man-Machine-Environment System Engineering: Proceedings of the 24th Conference on MMESE is the academic showcase of latest research papers selected from more than 500 submission in this field in 2024.

The second edition of this book presents the role of osmolytes in human health and diseases. Some of the chapters deal about the possibility of the use of osmolytes as diagnostic biomarkers and potential drug design for neurodegenerative and other human diseases. Other chapters also include reviews on the role of osmolytes in cancer, metastasis, infectious diseases, metabolic disorders, immunological disorders, and tissue regeneration. Importantly, the book also contain recent updates on the role of naturally occurring osmolytes in protein folding pathway, protein stability, and their underlying mechanisms. The book also covers the aspects that osmolytes could promote conformational alterations of transcription factors that favor metastatic behavior. Potential of the osmolytes in the various process of vaccine development, including enhancing the efficacy, production, and purification steps are also succintly described. Towards the end, the book also elucidates the use of specific molecules for the prevention of toxic gain of functions and restoration of function to disease-causing mutant protein. This book is an invaluable asset for the researchers especially working in osmolyte biology and scientists involved in basic and clinical research particularly neurodegeneration, diabetes, cancer, and metabolic disorders.

Anaerobic digestion is a core technology for sustainable waste(water) management and renewable energy recovery from waste sources. This book introduces and brings readers up to date with anaerobic digestion and its applications. It refreshes readers on the fundamentals of anaerobic digestion processes for normal and stressed scenarios, introduces techniques for stable system operation and predication, and explains the innovation in technology applications for waste valorization. By providing scientific and engineering fundamentals, the book equips professionals with the knowledge of knowing why and how to solve the problems in the application of anaerobic digestion.

This book provides a comprehensive view for plant microbe interactions towards stress management and microbiome-assisted approaches in sustainable agriculture. It is divided into four major sections. The book gives insights into the increasing threat of abiotic and biotic stresses and the accompanying challenges to modern agriculture. Through different chapters, the book shows how various microorganisms could ameliorate abiotic and biotic stress, and contribute towards food sustainability and restore ecosystem functioning. It provides a deep understanding of soil microbiome and its interaction with plants, to enhance food security. It further talks about metagenomic approaches for methodological tool for studying the soil microbiome. Separate sections on stress, talk at length about the various abiotic and biotic stresses that plants are faced it. The book culminates with an exciting section on microbiome-assisted approaches for combating stress. It talks about the different microbiomes such as rhizosphere, soil, phyllosphere and endophytic microbiome. The book would be beneficial to students, researchers and course instructors in microbiology, botany, plant pathology and agriculture.

This book gives an overview of pharmacoproteomics and its clinical applications, as well as the latest information on drug mechanisms at the proteome level, the relationship between proteomics and toxicity or resistance, and how proteomics aid in discovery of new drug targets. The book also highlights recent advances in analytical methods, analysis, and interpretation of pharmacoproteomic data.Pharmacoproteomics: Recent Trends and Applications is an ideal book for those working in pharmaceutical industries, as well as scientists, health care professionals, and researchers who work in the field of genomics, pharmacology, pharmacokinetics, toxicology, and pharmaceutical chemistry.

This edited book presents recent developments in the field of plant biotechnology involving highly efficient micropropagation for the commercial exploitation of nanomaterials (such as silver, cobalt, copper, zinc, magnesium, silicon, iron, nickel, manganese, and selenium nanoparticles, etc.). The book covers the concept, preparation, and synthesis of metallic and non-metallic nanoparticles, as well as their application in plant cell, tissue, and organ culture. Metal nanoparticles have gained significant attention in various fields, including plant cell, tissue, and organ culture. Their unique physical, chemical, and biological properties make them attractive candidates for applications in plant science. Nanomaterials are applied as plant growth regulators to improve plantlet quality by enhancing the quality of in vitro shoots, their growth, and development at both in vitro and ex vitro stages. Since then, the application of nanomaterials in micropropagation has paved the way for replacing previous culture mediums with new nanoparticle mediums, bringing better efficiency and simplicity to plant propagation operations. The book discusses mechanisms, explant surface disinfection, media sterilization, abnormal phenomena, morphogenesis, physiological-biochemical processes, and the accumulation of economically valuable crop compounds in culture mediums supplemented or replaced by metal ions with metal nanoparticles. This book will interest teachers, researchers, scientists, capacity builders, and policymakers. Additionally, it serves as additional reading for undergraduate and graduate students in agriculture, forestry, ecology, soil science, and environmental science.

This edited book focuses on plant growth regulator synthesis, potential applications, stress tolerance mechanisms and preservations. It explores the recently registered molecules strigolactones, karrikins, and hemin-mediated regulation of plant biology. Chapters cover the integration of plant hormones in the biological system as an opportunity for sustainable agriculture. This book explores the latest information on plant growth regulators covering both theoretical and practical aspects. Plant growth regulators are organic chemical compounds that alter or regulate the metabolism in plants. In plants, plant growth regulators play the role of biostimulants that can enhance resistance to stress. Plant growth regulators in low concentrations often lead to vital improvements and high yields in crop plants. Plant growth regulators are involved in several physiological, morphological, and biochemical mechanisms associated with plant growth, development and defence againststresses. This book brings together the latest research work on plant growth regulators and their emerging importance. The book is a useful read for students, researchers, and instructors in the field of plant biology.

Whole-cell biocatalysis is a promising and emerging field of biological science that is mostly based on advancements in biosystems engineering for the production of useful products such as chemicals, fuels, and pharmaceuticals. It is a unique platform that provides an efficient catalytic system at affordable cost and with low maintenance. Recent studies have proven that whole-cell catalysis is very useful in conducting many complex and complicated chemical reactions that could be executed with greater ease and in an eco-friendly manner in ambient conditions with zero/minimal ecological effect. This has made whole-cell biocatalysis very popular and a center of significance in the field of modern biological catalysis.This new volume offers a comprehensive understanding of whole-cell biocatalysis, beginning with an introduction and an overview of relevant tools and techniques. It presents the basic as well as the advanced concepts of whole-cell biocatalysis, thus acting as a complete guide for the reader. It looks at the promising developments that have taken place in the past decade and discusses the application of computational tools, the use of metabolic flux systems, and the role of metabolic networks for the cell system development for whole-cell catalysis. The chapters explore whole-cell biocatalysis for the production of chemicals, of fuels, and for environmental restoration, with case studies and success stories that showcase new developments in the technology.This volume provides a valuable presentation of whole-cell biocatalysis for graduate students, faculty, industry professionals, and others working in biochemistry and bio-systems engineering.

This new book provides a detailed overview of some of the fundamental aspects of nanocarbons and their allotropic forms, their preparation techniques, and their applications in several fields of interest. New forms of carbon have the potential to revolutionize many aspects of research, including drug delivery, catalysis, energy conversion and storage, high-strength physics, structural engineering, and more. This volume covers the recent literature on carbon with emphasis on the emerging carbon-based materials developed to date, studies of their properties, and possible prototypes fabricated for practical applications. It covers myriad carbon-based nanomaterials of distinctive features and their application in various fields.

The book focuses on environmental monitoring, pollution discharge control and management, environmental pollution governance, ecological remediation technology, and environmental sustainability. With the rapid growth of global population and the development of industry and cities, environmental pollution problems are becoming increasingly serious, affecting people's lives and social development. In order to protect the environment and achieve sustainable ecological development, we need to maintain research on environmental pollution governance and ecological remediation. This book aims to promote scientific information interchange between scholars from the top universities, research centers, and high-tech enterprises working all around the world and is a valuable resource for those in both academia and industry.

This book summarizes the recent advancements for biomaterials in the field of cardiovascular disease, including drug delivery system (gene, protein, drug), implant interventional instrument (heart valve, heart blocker, stent, artificial blood vessel, patch, artificial heart, cardiac pacemaker, etc.) have been innovated and applied to the clinical uses to treatment of cardiovascular disease. Through the summary of this book, readers will have comprehensive and advanced understanding of the application of biomaterials in the field of cardiovascular disease.

This book accumulates the most recent advancements in the field of bioengineering regarding hybrid science named nanobiotechnology and enriches the readers with vast and comprehensive knowledge about different biomedical applications of nanomaterials. It includes drug and gene delivery, tissue engineering, antimicrobial properties, hyperthermia, cancer therapy, bioimaging, biosensing, photoablation therapy, etc., utilizing the potential of different nanomaterials that are helpful for the well-being of diseased individuals. Furthermore, the concerns about multidrug-resistant microorganisms are increasing daily in the healthcare system. Since conventional therapies fail to combat various infectious diseases, novel nanotechnology techniques provide an alternative approach to developing innovative biomaterials. The novel features of nanomaterials need to be exploited for use in the biomedical engineering domain. They should be fabricated so that the novel multifunctional nanomaterials notonly improve drug efficacy but also reduce their side effects. Moreover, a detailed understanding of the nanotoxicological effects of promising biomedical nanomaterials should necessarily be explored using the cell culture approach. Corona of nanomaterials should be investigated in detail to determine its fate in the biological system regarding safety concerns. This is the most important feature that is novel and explored in this book and would be very helpful for customers like clinicians, scientists, engineers, and technicians who will gain extensive knowledge from this book and work together to get the desired results in the healthcare sector.

Environmental Nanotoxicology: Combatting the Minute Contaminants is a comprehensive guide to the rapidly evolving field of nanotoxicology and its implications for environmental health and safety. This book results from the collaborative efforts of leading experts and researchers from diverse disciplines, aiming to thoroughly understand the interactions between nanomaterials and the environment and their potential impacts on the delicate balance of our ecosystems.Nanotechnology has witnessed remarkable innovations leading to the development of nanomaterials with novel properties and applications across various industries. Alongside these innovations, concerns have arisen about the potential risks that nanomaterials may pose to the environment and living organisms. This book addresses these concerns by comprehensively exploring the field's key concepts, principles, and methodologies. It includes case studies and offers insights into developing appropriate regulatoryframeworks and guidelines for the responsible use and disposal of nanomaterials. The book is a valuable resource for researchers and professionals working in nanotoxicology on the complex challenges posed by the intersection of nanomaterials and the environment. It is also an essential reference for students studying environmental science, toxicology, and nanotechnology.

This edited book brings together a diverse group of researchers to address the challenges posed by global mass poisoning caused by lead contamination of soil and plants. Lead is among the elements that have been most extensively used by man over time. This has led to extensive pollution of surface soils on the local scale, mainly associated with mining and smelting of the metal and addition of organic lead compounds to petrol. Release of lead to the atmosphere from various high-temperature processes has led to surface contamination on the regional and even global scale. Lead is particularly strongly bound to humic matter in organic-rich soil and to iron oxides in mineral soil and is rather immobile in the soil unless present at very high concentrations. In addition, plants grown on lead-rich soils incorporate lead and thus the concentration of lead in crop plants may be increased. Lead enters in the food chain through consumption of plant material. A high concentration of lead has been found to be harmful to vegetation. As the lead concentration increases, it adversely affects several biological parameters and eventually renders the soil barren. The book sheds light on this global environmental issue and proposes solutions to contamination through multi-disciplinary approaches. This book contains three sections. First section describes the different sources and distribution of lead in soil and plant ecosystems. Second section explains the health risks linked to lead toxicity. Third section addresses sustainable lead toxicity mitigation strategies using the potential applications of recent biological technology. This book is a valuable resource to students, academics, researchers, and environmental professionals doing field work on contamination throughout the world.

Advances in Applied Microbiology, Volume 126 continues the comprehensive reach of this widely read and authoritative review source in microbiology where users will find invaluable references and information on a variety of areas relating to the topics of microbiology. - Contains contributions from leading authorities in the field - Informs and updates on the latest developments in the field of microbiology - Includes discussions on the role of specific molecules in pathogen life stages, interactions, and much more

Novel Formulations and Future Trends, Volume Three in the Recent and Future Trends in Pharmaceutics series, explores aspects of pharmaceutics with an original approach focused on technology, novelties and future trends. It discusses the most important developments in drug delivery, including important and exciting areas such as mucosal, implantable, transdermal, gastroretentive, vaccine and targeted drug delivery systems. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. This is an essential reference for researchers in academia and industry as well as advanced graduate students. New technologies are also explored including 3D printing and computational pharmaceutics. - Explores the most recent technologies in drug delivery in detail - Contains contributions from the leading experts from academia, research, industry and regulatory agencies - Includes high quality illustrations, flow charts and tables for easy understanding of concepts - Discusses practical examples and research case studies

Quantum Sensing at the Interface of Nanotechnology Integrated Microfluidics provides broad multidisciplinary coverage of innovative quantum sensing technologies suitable to industries in the engineering, biomedical, healthcare and environmental sectors. Sections discuss emerging quantum sensing and with an introduction to microfluidic devices, smart sensors, the role of nanotechnology, smart sensing, and the role of quantum technology and artificial intelligence for nano-enabled microfluidics. Sensing technologies and nano-enabled microfluidics and their biomedical and industrial applications are explored. This will be a useful resource for those in research and industry interested in biotechnology, nanotechnology, sensing technology and their applications in multidisciplinary fields. - Provides an introduction to the types of microfluidic devices, smart sensors, and the role of nanotechnology - Covers smart sensing for multidisciplinary sectors - Explores the challenges and prospects of nano-microfluidics systems

Biocontrol Agents for Improved Agriculture, a volume in the Plant and Soil Microbiome series, presents both an advanced and current description of the important role of plant and soil microbiome in plant disease management. Including the latest biotechnological interventions for harnessing plant and soil microbiome and their potential in controlling plant pathogen/ disease, as well as the commercialization of biocontrol products and exploration of microbial derived bioactive compounds, this book provides an important reference on the challenges of biocontrol products. Sections explore the bacterial and fungal species successfully applied as plant and soil inoculant for the effective management of plant diseases. As these microbial biocontrol agents not only suppress the plant disease, but also enhance the growth or agricultural production in sustainable ways, the book focuses on the molecular aspect of plant- pathogen interactions and their biocontrol strategies via the use of plant and soil microbiome. This book is an important reference for those seeking sustainable, safe options for protecting against microbial agricultural loss and environmental damage. - Presents emerging microbial biocontrol strategies for addressing plant pathogens - Covers production and commercialization of biocontrol products - Includes accessible, informative illustrations of current trends in microbial biotechnology

This proceedings volume constitutes peer-reviewed full-length papers contributed by the Authors and tailored on various thematic areas of the 1st International Conference on Sustainable Advanced Technologies for Environmental Management (SATEM – 2023). The areas of research covered by these papers include but are not limited to: •Sustainable Water Quality Management •Advanced Water Treatment Technologies •Advanced Wastewater Treatment Technologies •Assessment and Control of Air Pollution •Solid and Hazardous Waste Management •Prevention of Groundwater Contamination •Wetland Management/Phyto- and Phyco-remediation •Case Studies in Urban and Rural Pollution Control •Management of Emerging Contaminants •Innovative Techniques for measuring environmental pollutants

This book compiles recent studies about edible coatings and how they have improved food products, packaging techniques, and product quality to cause fewer health risks. Food Coatings and Preservation Technologies presents the most recent studies about the application of edible coatings to a wide variety of foods. Edible coatings are globally utilized for preventing food product contamination from harmful microorganisms and pathogens. This book highlights the developments made in designing new edible coatings. Herein, particular attention is given to the main components, manufacturing methods, and their application to specific products. The book also discusses the current state-of-the-art alternative to conventional package usage, providing the main features biodegradable packaging should meet for distinct uses for the conservation and improvement of various food products. This information will be helpful for processors to select the best coating material and its effective concentration for different fresh and minimal processed vegetables. Each chapter delves into edible-based coating research and critical developments to enhance food preservation standards. The first section focuses on biopolymer-based edible coatings, food packaging, and preservation. It provides a comprehensive understanding of the current state and critical developments in biodegradable polymer packaging systems for food applications. As technology advances, the next section highlights ongoing research focusing on optimizing coating effectiveness and the development of eco-friendly and sustainable materials. This section's objective is to identify edible materials and combine the most recent information available to provide a comprehensive understanding of formulation methods and approaches to enhancing the properties of the coatings applied to food products. The final section discusses encapsulation techniques and levels of retention to improve shelf-life. Readers will find in this book information concerning: The efficiency and functional properties of edible coating materials; Feasibility studies performed on new process evaluation, safety and toxicity determination, regulatory assessment, and consumer studies regarding the commercial uses of edible coatings; Coating technologies that present a promising avenue to enhance the delivery, stability, and efficacy of medical foods and nutraceuticals; Shelf-life testing that suggests future directions; Novel practical and reliable tools that are applicable in the industrial process. Audience The book is aimed at chemists, food technologists, food scientists, nutritionists, dietitians, pharmaceutical technologists, biochemists, and engineers, as well as postgraduate, PhD students and postdocs working in the area of edible food coatings and prevention technologies.

This book offers an insightful exploration of drug repurposing, an innovative approach to drug discovery and development that has the potential to revolutionize the field of medicine. It begins with an introduction to drug repurposing and its history, providing a comprehensive overview of the subject. The readers will embark on a journey through the diverse landscape of drug repurposing strategies. From in silico methods of predicting drug-disease associations to experimental approaches to the integrations of artificial intelligence (AI) and machine learning (ML) in drug repurposing for validating repurposed candidates. The book also delves into the application of drug repurposing in various disease areas, including cancer, inflammatory disorders, and CNS disorders. It explores the potential hurdles involved in the regulatory aspects of the process. The book further covers drug products under clinical trials and provides an overview of the future perspectives of drug repurposing. With its detailed and informative content, this book is a must-read for researchers, clinicians, and healthcare professionals interested in the exciting field of drug repurposing.

The book provides information on the sources of arsenic contamination of groundwater and their impacts in the first part of the book consisting of 8 chapters. Process developments such as nano-adsorbents for removal of arsenic and other heavy metals are discussed in the second part of the book that comprises of 4 chapters. The third part of the book includes 4 chapters on technological interventions for the removal of arsenic such as indigenous ceramic membranes and Subterranean Arsenic Removal (SAR). The fourth part of the book deals with arsenic contamination in food materials and food chain systems, and consists of 5 chapters. Arsenic has long been associated with a variety of health complications in the human body. In order to address this, a chapter on arsenic contamination and impacts on human health has been included in the fifth part of the book. The book would be a valuable reference material for the scientific community in developing countries working on community water supply and treatment, food safety, public health and policy.

This book elaborates on the sustainability of biofuels and biochemicals production via thermochemical conversion pathways. Sustainability encompasses the social, economic, environmental, political, and thermodynamic efficiencies of a production technology. Assessing the sustainability of wastes conversion pathways would help pinpoint inefficiencies hence improving the process economically, environmentally, and thermodynamically. This book discusses the major sustainable potential feedstocks/waste for thermochemical conversion into bioproducts such as biodiesel and bioelectricity. Though there exist many pathways for thermochemical waste conversion (such as combustion, gasification, and pyrolysis) which operate on laboratory, pilot and commercial scales, their sustainability indices are scarce as there exist few sustainability assessment tools to help pinpoint inefficiencies. This book assesses the sustainability of various types of thermochemical conversion pathways using technoeconomic analysis as well as exergetic life cycle assessment tools. Common sustainability issues and the way forward for sustainable thermochemical wastes conversion into bioproducts are detailed in this book. For overall sustainability, thermochemical waste conversion process development alternatives are also discussed in this book. Given its scope, this is a valuable resource for renewable energy policy makers, bioprocess researchers in academia and related industries, students studying in the fields of Green Chemistry, Chemical and Mechanical Engineering as well as the general publics who have great interest in biofuels for sustainable development. Almost all books on thermochemical biomass conversion address only the process and new technologies, but few tend to address the technical and thermodynamic issues pertaining to sustainability due to the use of fossil fuel in the manufacturing process. This book bridges this knowledge gap, and subsequently outlines specific exergetic improvement options for biofuel and biochemicals production which is scarce in literature. This book assesses the sustainability of bioprocess technologies in a more concise manner for students to understand and apply the knowledge in their future engineering careers.

This book describes numerous issues and brings an improved understanding of a key agenda item for the sustainable development goals (SDGs). The SDGs represent an urgent call for action by all countries, developed and developing, working jointly within the global community. A few of the industries it supports include food processing, energy, biomedical science, space research, drug delivery, and biosensors. This book highlights multidisciplinary solutions for protecting the environment while ensuring the future of our planet. The book mainly targets undergraduates, postgraduates, and doctoral students who are working in materials science and researchers across the world working in interdisciplinary research for climate change for sustainable growth.

This volume brings together leading international experts to offer a unique and timely perspective on geomicrobiology through their latest research and findings. Chapters address interactions of marine and freshwater microorganisms contributing to geochemical cycles, including biochemical mechanisms for mineralization and transformation of solid minerals and dissolved metals. In addition, the resilience and physiological elasticity of specific bacteria in extreme environments is discussed, such as mechanisms of metal homeostasis and electrochemistry involving extracellular electron flow. Further coverage includes resource recovery (metals, minerals) using microbial-driven processes and technologies, with the aim to contribute to a better understanding of microbial potential within the framework of circular economy. This book is designed for professionals and students, including environmental engineers, microbiologists, and individuals studying the interaction of bacteria with metals and minerals in the environment. It is also a resource for students in academic programs or short courses focused on bacterial diversity in the environment, systems of bacterial energetics, resource recovery, and bacterial activities in extreme or nutrient-stressed environments..

This book covers the fundamental principles of molecularly imprinted polymers (MIPs) and their synthesis methodologies, offering readers a solid understanding of these unique materials. It delves into the design and selection of template molecules for imprinting, as well as polymerization techniques and strategies for optimizing MIP performance. With a focus on real-world applications, the book showcases the wide range of environmental health problems that MIPs can address. It discusses the detection and quantification of pollutants in air, water, and soil using MIP-based sensors and biosensors. Additionally, it explores the use of MIPs in environmental remediation, such as the adsorption and removal of contaminants, as well as the development of MIP-based materials for water and soil treatment. The book also highlights the analytical applications of MIPs in environmental health, including separation and purification techniques, sample preparation, and preconcentration methods. It examines how MIPs can be integrated into analytical instrumentation and detection systems to enhance environmental analysis. By bringing together interdisciplinary knowledge from the fields of environmental science, chemistry, polymer science, analytical chemistry, and environmental engineering, this book provides readers with a comprehensive understanding of the potential of MIPs as artificial antibodies for environmental health. With its emphasis on real-world applications and case studies, it offers practical insights that researchers, academics, and professionals can apply in environmental monitoring, remediation, and analysis projects.

This book serves as a guide, leading readers towards a world where waste ceases to be a burden, but a wellspring of possibilities. Whether the goal is to enhance expertise, ignite creativity, or develop a thorough grasp of waste's transformative possibilities, this book serves to achieve a more sustainable and prosperous future. It provides an invaluable treasure of knowledge for readers, researchers, working professionals, and academics alike, and offers a comprehensive roadmap to address the waste crisis with sustainable solutions. The book introduces readers to a diverse range of sustainable approaches that address the pressing challenges of waste management and resource conservation. From converting waste into building materials to employing waste in innovative 3D printing applications, these sustainable approaches empower individuals to make informed choices for a greener future. It provides in-depth insights that captivate waste management and environmental specialists while offering accessible entry points for those new to the subject.

This book covers wide aspects of algal technology and algae-based biorefinery aspects. Algae are the most prevalent, primitive, and abundant microbes on Earth, however, the commercialization of algal-based value-added products is still low due to the negligible dissemination of knowledge flow among the stakeholders and researchers.This book provides up-to-date information on the cultivation of microalgae, their harvesting, downstream processing, and diverse applications. It further discusses the macromolecules existing in microalgae, such as proteins, carbohydrates, and lipids, poly-unsaturated fatty acids, peptides, exo-polysaccharides, flavonoids and antioxidants. This book also highlights the advantages and some real-time challenges before the establishment of sustainable algal-based biorefineries. Further, it includes clear flow charts and figures in each chapter to aid in interpretation of every technical concept. This book motivates readers, entrepreneurs, and young farmers to exploit easily growing microalgae through cottage to large-scale biorefineries and start their own businesses for the production of value-added products.

This book focuses on the various applications of microorganisms for sustainable environment and the reduction of hazardous pollutants released in various forms, including xenobiotics, e-waste, pesticides, insecticides, plastic, heavy metals, paper waste, medical waste, textile dyes, and their impact on environmental and human health. The book involves a series of research reports that explain the application of microbes used to solve real-life issues raised due to changes happening in environment, including pollution, by covering applications, including the use of bacteria, fungi, microalgae and biofilm in the detection and degradation of crude oil, pesticides, dyes, e-waste, heavy metals and other pollutants. It also focuses on integrative strategies in the application of microbial nanomaterials for remediation of pollutant. This material will help environmental scientists and microbiologists to learn about existing environmental problems and suggest novel ways to control or contain their effects by employing various treatment approaches.