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Industrial crops offer farmers new market opportunities to increase their revenue by producing high-value products, focusing on fiber, forest, and energy crops, industrial oilseeds, rubber and resins, pharmaceuticals, and more. Technological innovations in agriculture have facilitated higher yields, but conserving crop genetic resources and diversity remains crucial for sustainable agricultural production. This poses a challenge that can be addressed through modern tools of biotechnology and genomics, utilizing the wealth of sequenced plant genomes. This book addresses the need for knowledge in managing the risks and conservation of genetic diversity associated with advanced technology. It provides comprehensive coverage of plant genomics and biotechnology, catering to post-graduate students, researchers, employees of seed and biotechnology companies, as well as instructors in plant genetics, breeding, and biotechnology fields.

The book explains the use of natural products as scaffolds in tissue engineering. It presents an introduction to the concept of natural product-based scaffolds and explores various fabrication strategies for their synthesis. The book highlights the wide range of applications of these scaffolds in tissue engineering, including their use in tissue regeneration, wound healing, plastic surgery, and breast reconstruction. Specific natural products, such as gums (xanthan, gellan, arabic, guar, ghatti gum), chitosan, collagen are discussed in separate chapters. In addition, various application of natural product loaded PCL and PLA scaffolds have also been discussed. Each chapter focuses on the application of these natural product based scaffolds and explores their potential in tissue engineering. It also covers specific applications of these scaffolds in tissue regeneration, including angiogenesis, bone, skin, and nerve tissue regeneration. The book addresses important considerations regarding the toxicity and regulatory aspects of natural product-based scaffolds and explores the challenges associated with their implementation and emphasizes the need for safety and compliance in their use. Overall, the book provides a comprehensive overview of the field. It serves as a valuable resource for researchers, scientists, and professionals in the field of tissue engineering.

This book provides insights into the recent developments in the field of bioprocess technology and bioreactor design. Bioprocess engineering or biochemical engineering is a subcomponent of chemical engineering, which encompasses designing and developing those processes and equipment that are required for the manufacturing of products from biological materials and sources, such as agriculture, pharmaceutical, chemicals, polymers, food, etc., or for the treatment of environmental process, for example, waste water. The main focus of this book is to highlight the advancements in the field of bioprocess technology and bioreactor design. The book is divided into various chapters briefing all aspects of bioprocess engineering and focusing on the advances in bioprocess engineering. The book summarizes introduction to bioprocess technology and microbiology, isolation and maintenance of microbial strains, and sterilization techniques for advanced-level students and researchers. Different models depicting kinetics of microbial growth, substrate consumption, and product formation are discussed. The applications of enzymes have increased tremendously and therefore understanding their metabolic pathways to increase yields is also briefly discussed. The calculations of mass and energy balances associated with entropy changes and free energy. This book also covers the approaches for handling different types of cell cultures and current advancements in the area of bioprocess strategies for different culture types, which scientists and researchers working in the different cell cultures can refer to. The downstream processing of various industrially important products is also a part of this book. Apart from that, the process economics which ensures the feasibility and quality of any biological process is also dealt with as the last section of the book.

Emergence of lifestyle diseases, e.g., type II diabetes, cancers, obesity, cardiovascular disorders, liver cirrhosis, etc., are exponentially increasing day by day. Modern drifts toward the utilization of herbal medicines in different healthcare aspects necessitate (demand) the replacement of synthetic molecules with phytoconstituents because of their biocompatibility, biodegradability, economic extraction process, and ready availability from the natural source. This book provides a thorough insight into the comprehensive and up-to-date trends of phytomedicines in the management of lifestyle diseases and its mechanisms, modern methods of extraction and purification of phytoconstituents, and chemical characterization as well as standardization of phytoconstituents using modern equipments.

This book provides technical information on different biological and hybrid wastewater treatment systems for treatment of wastewater and reuse. The contained information helps in tracking their progress of such systems toward practical and field-scale applications. The book also includes strategies to be adopted for minimizing the losses and maximizing the benefits. Additionally, it includes methods for protecting the environment through the application of advanced biological and hybrid wastewater treatment technology. Furthermore, it discusses the crucial parts that science, technology, and innovation play in the formulation, implementation, and administration of wastewater treatment policy. It highlights the challenges that must be overcome to adopt biological and hybrid wastewater treatment infrastructure regulations successfully and provides some answers. It investigates how the biological and hybrid wastewater treatment technology may be used in a wide variety of field's sets apart from other on-the-shelf publications on the market. Also, it delves into the core concepts of biological and hybrid wastewater treatment systems. It explores how these concepts can be modified to fit a variety of contexts and uses. Applications such as managing facilities, dealing with pandemics, urban wastewater treatment and reuse, farming, and other applications are included in this book. This book is helpful to researchers, entrepreneurs, professionals, planners, policymakers, environmental engineers, and others interested in biological and hybrid wastewater treatment system management strategies through the application of breakthroughs in biological and hybrid wastewater treatment technologies. Also, it is useful as a fundamental source of information and state-of-the-art knowledge to graduate students, university faculties, and researchers in the fields of environmental sciences/engineering, biological and chemical sciences, and NGO. It is also useful to entrepreneurs, professionals, and planners in policy and decision making at the local, state, and national levels for many countries.

The book introduces readers to the latest developments in biotechnological methods used for improving the cultivation of silkworms. The text focuses on implementing biotechnological approaches, ranging from basic to advanced techniques, on enhancing silk production, increasing abiotic stress resilience, improving disease tolerance, and developing resistance in silkworm crops. With the current climate crisis and growing demand for high-quality silk, biotechnological applications have become essential in addressing the urgent need to increase silk production. The field of sericulture has made significant breakthroughs, such as identifying DNA markers, linkage association, genome-wide association studies, generating mutants, and introducing transgenic silkworms. Developing silkworms with improved cocoon yield and disease resistance is crucial to boost silk production. The book covers fundamental principles and recent advancements and delves into various methodologies employed inseri-biotechnology for improving silkworm crops. These methodologies include next-generation sequencing for DNA sequencing, using molecular markers to enhance abiotic stress tolerance (specifically high temperature and humidity conditions), expression analysis, RNA interference, gene knockout approaches to bolster disease resistance, and transcriptomics to enhance economically significant parameters such as silk content. The book explains these topics in detail and includes contemporary research appraisals, extensive discussions, and an evaluation of the benefits and risks associated with the use of biotechnological tools. This book serves as an invaluable reference for researchers and academics in biotechnology, molecular biology, and sericulture while also serving as an informative starting point for budding researchers.

This book focuses on the various applications of microorganisms for sustainable environment and the reduction of hazardous pollutants released in various forms, including xenobiotics, e-waste, pesticides, insecticides, plastic, heavy metals, paper waste, medical waste, textile dyes, and their impact on environmental and human health. The book involves a series of research reports that explain the application of microbes used to solve real-life issues raised due to changes happening in environment, including pollution, by covering applications, including the use of bacteria, fungi, microalgae and biofilm in the detection and degradation of crude oil, pesticides, dyes, e-waste, heavy metals and other pollutants. It also focuses on integrative strategies in the application of microbial nanomaterials for remediation of pollutant. This material will help environmental scientists and microbiologists to learn about existing environmental problems and suggest novel ways to control or contain their effects by employing various treatment approaches.

Blockchain is a new type of technology that combines and secures information exchange between different stakeholders such as medical practitioners, patients, healthcare providers, and other applicable parties. Among them, Blockchain Technology is one of the most important areas in the bioinformatics application of biomedical research and healthcare systems utilizing unique requirements and integration features. All the chapters are written by experts and researchers working in various areas of the biomedical and healthcare domain and they also dive into one of the most overlooked methodological, practical, and moral questions to secure and handle the enormous amount of data being generated from IoT-enabled biomedical and healthcare systems. In the beginning, this book presents an overview and then discusses open issues, challenges, and applicability aspect of Blockchain technology in healthcare. Then, this book presents a variety of perspectives on the most pressing questions in the field, for example: how IoT can connect billions of biomedical and healthcare information; how the blockchain-based secure access control mechanisms in biomedical and healthcare work; how to address the Quality-of-Service (QoS) and real-time accessibility requirements for healthcare applications; and how to ensure communication with efficiency. Also, it discusses Blockchain for IoT-enabled healthcare systems and presents a comparative analysis with respect to various performance evaluation metrics too.

This book describes the basic concepts and recent advances in new discoveries and technologies related to microbial omics and their role in environmental research and human health. The term'omics'refers to a blend of high-throughput analysis and traditional methods including genomics, transcriptomics, proteomics, lipidomics and metabolomics for a variety of applications in the field of life sciences, biomedical sciences, environmental sciences, and related industries. The book aims to fill the existing gap in terms of a comprehensive approach that incorporates recent advances in this dynamic field and provides an answer to why this field requires an interdisciplinary research approach. The focus of this book is on the applications of genomics, epigenomics, metagenomics, integrative omics, machine learning and microbiome research in environmental health, disease, wastewater epidemiology, antibiotic resistance, drug discovery, cancer, production of secondary metabolites of microbial origin, oxidative stress alleviating mechanisms, etc. The overall construction of this book emphasizes three major perspectives, namely, elaborate knowledge from fundamentals to recent advances in technologies about omics in general and its application in microbiology, environment, and health in particular; illustrative figures capable of easy visualization of complex pathways; and serving as a platform for highly demanded bioinformatics strategies including relevant codes, programming scripts, machine learning and use of artificial intelligence strategies needed to streamline the research outcomes. With global contributions from authors from internationally renowned organizations who excel in relevant research, this book will benefit bibliophiles and prospective audiences from the research fraternity, academia, professionals, and experts in the field of life sciences, biomedical as well as industries related to the development of drug design and novel advances in biotechnological applications.

This book provides a comprehensive introduction and review of state-of-the-art biotechnological tools in enhancement of bioactive compounds in medicinal and aromatic plants. Plant bioactive compounds are plant-based natural products that display a variety of pharmacological applications. These bioactive compounds are important as medicines, pigments, flavorings and drugs because most of the pharmaceutical industries are highly dependent on medicinal plants and their extraction. The book introduces a systematic overview of state-of-the-art biotechnological techniques such as Omics, Crisper /Cas9 and RNAi to enhance the plant bioactive contents as well as enlists various in vitro techniques, hairy root culture and transgenic technology to enhance plant bioactive contents using plant tissue culture approaches. The book also provides an overview of the role of induced mutation, biotic and abiotic stress to increase the bioactive contents in plants and discusses the significant role of endophytes to enhance the contents of plant bioactive compound. The book also opens discussions related to standard operating procedures using hydroponics system of cultivation for significant enhancement of bioactive compound(s) and much more. This book serves as an excellent reference book for the researchers working in the field of plant secondary metabolites and pharmaceutical industries at global level.

This book provides a meticulous view on methodological drug discovery and development insights from bench to bedside. The current book threads almost each step encompassing drug the discovery and development of a molecule. The chapters focus on computational modus operandi, pharmacological optimization approaches, modern high-throughput screening methods and in-vitro procedures, role of structural biologists in drug discovery and development, medicinal chemistry approaches for drug design, formulation and drug delivery, in-vivo evaluations of candidate molecules, clinical trial procedures and others. The book also covers specific case studies, regulatory approval proceedings, and industrial view point alongside the aforementioned conceptual layout. And at the same time, the volume integrates medical, biological, medicinal, pharmacological and computational streams, and it is suggested as an ideal guideline to a wide audience including molecular biologists, biochemist, pharmacologists, medicinal chemist, toxicologists, drug discovery and development researchers, and all other students interested in these disciplines.

This book assembles state-of-the-art approaches for harnessing light energy as a model to develop natural systems such as biofuels. After the basics and potential of photosynthesis of microalgae it discusses topics from engineering micro-algae towards increased photosynthetic efficiency till the optimization of photobioreactor techniques for enhanced biotechnological applications such as cyanobacteria.

This book contains a compilation of papers presented at the II International Conference on Environmental, Industrial and Applied Microbiology (BioMicroWorld2007) held in Seville, Spain on 28 November - 1 December 2007, where over 550 researchers from about 60 countries attended and presented their cutting-edge research. The main goals of this book are to: (1) identify new approaches and research opportunities in applied microbiology, presenting works that link microbiology with research areas usually related to other scientific and engineering disciplines; and (2) communicate current research priorities and progress in the field. The contents of this book mirror this focus.Microbiologists interested in environmental, industrial and applied microbiology and, in general, scientists whose research fields are related to applied microbiology can find an overview of the current state of the art in the topic. In addition to the more general topic, some chapters are devoted to specific branches of microbiology research, such as bioremediation; biosurfactants; microbial factories; biotechnologically relevant enzymes and proteins; microbial physiology, metabolism and gene expression; and future bioindustries.

As natural phenomena are being probed and mapped in ever-greater detail, scientists in genomics and proteomics are facing an exponentially growing vol­ ume of increasingly complex-structured data, information, and knowledge. Ex­ amples include data from microarray gene expression experiments, bead-based and microfluidic technologies, and advanced high-throughput mass spectrom­ etry. A fundamental challenge for life scientists is to explore, analyze, and interpret this information effectively and efficiently. To address this challenge, traditional statistical methods are being complemented by methods from data mining, machine learning and artificial intelligence, visualization techniques, and emerging technologies such as Web services and grid computing. There exists a broad consensus that sophisticated methods and tools from statistics and data mining are required to address the growing data analysis and interpretation needs in the life sciences. However, there is also a great deal of confusion about the arsenal of available techniques and how these should be used to solve concrete analysis problems. Partly this confusion is due to a lack of mutual understanding caused by the different concepts, languages, methodologies, and practices prevailing within the different disciplines.

While the sequence of the human genome sequence has hit the headlines, extensive exploitation of this for practical applications is still to come. Genomic and post-genomic technologies applied to viral and bacterial pathogens, which are almost equally important from a scientific perspective, have the potential to be translated into useful products and processes much more rapidly. Genomics, Proteomics and Vaccines introduces the history of vaccinology and discusses how vaccines are expected to evolve in the future. It describes the relevant technologies, including genome sequencing and analysis, DNA microarrays, 2D electrophoresis and 2D chromatography, mass spectrometry and high-throughput protein expression and purification. The book also features examples of the exploitation of genomics and post-genomics in vaccine discovery, and contains useful descriptions of the biology and pathogenesis of clinically important bacterial pathogens. This book should be of interest to all those working in vaccine discovery and development in pharmaceutical and biotechnology companies as well as in academic institutions

A world wide interest in the various aspects of high pressure in the field of biological science led to the First International Conference on High Pressure Bioscience and Biotechnology in Kyoto, Japan. High pressure bioscience encompasses the fields of food sciences, pharmacy and medical fields and some high pressure techniques are used in the production of industrial products. Moreover, high pressure is a valuable tool for the study of natural macromolecules including biomembranes which are composed, primarily, of lipid and protein. Many intermediate processes in the pressure-induced protein unfolding have been discovered, as a result. This book covers the entire range of current high pressure bioscience and its possible applications.