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The elapsing time from producer to consumer has significantly increased as a result of food marketing and trade globalization. Consequently, maintaining quality along the food value chain is becoming a significant challenge. Postharvest losses are considered a major component of food loss and waste in the supply chain from farmers to consumers, due to improper handling, storage, transport, preservation techniques and spoilage. Postharvest science aims to extend the shelf life of fresh and perishable commodities, and to reduce heavy losses, thereby contributing to food security. While significant progresses have been made in postharvest preservation and shelf-life extension, the continuous development of emerging technologies have changed our vision on postharvest science. Furthermore, recent advancements in molecular engineering of horticultural crops for quality improvement; the development of genomics, transcriptomics, proteomics, and metabolomics have led to a better understanding of the physiology and the biochemistry of the senescence processes, resulting in better preservation and improved production of fresh crops. This two-volume work focuses on innovative technologies that extend and preserve shelf life of fruits and vegetables. Volume 1 offers a review on the state of the art modern technologies in the postharvest filed. The accompanying Volume 2 explores advanced and novel technologies after harvest, particularly the application of nanotechnologies to packaging materials.

Agriculture is facing unprecedented challenges including climate change, declining arable land, and a growing global population. To meet the increasing demand for food while minimizing environmental impact, innovative solutions are required. Nanotechnology offers promising avenues to enhance agricultural productivity, sustainability, and food security.'Revolutionizing Agriculture: A Comprehensive Exploration of Agri-Nanotechnology'is an ambitious and timely book that sheds light on the transformative potential of nanotechnology in agriculture. This book is an exploration of agri-nanotechnology covering foundational principles, various applications, environmental considerations, and future trends. It serves as a valuable resource for researchers, academics, students, policymakers, and industry professionals interested in the intersection of nanotechnology and agriculture. By addressing both the scientific and societal implications of agri-nanotechnology, this book contributes to the sustainable development of agriculture in the 21st century. This book... Expands existing knowledge and understanding of applications of nano-materials in agriculture, exploring their chemical structures, properties, and biological activities; Provides readers with a foundational understanding of nanoscale science and its relevance to agriculture; Explores various types of nanomaterials and their applications in crop production, soil management, and pest control; Discusses the use of nanosensors for real-time monitoring of soil and crop conditions, as well as data analytics for precision agriculture; Addresses the development of nanopesticides, nanofertilizers, and nanodelivery systems to reduce chemical use and enhance crop protection; Examines how nanotechnology can contribute to sustainable practices such as water management, waste reduction, and energy efficiency; Discusses the regulatory framework and ethical concerns surrounding the use of nanotechnology in agriculture; Bridges the gap between the fields of agriculture, biotechnology, chemical and physical sciences.

This book reviews all important aspects of plant genome editing to shed new light on these genome editing technologies together in crop improvement and sustainable agriculture. The book is divided into three areas: the first of which reinterprets plant genome studies from an overview perspective, examining the safety and risk assessment of plants as well as breeding-related outcomes. The second area discusses recent advances in the understanding of crop improvement. A wide range of plant stress tolerance in relation to plant genome editing is then addressed, before turning attention to specific species approaches including rice, maize, wheat, and soybean. The entire book is devoted to an updated knowledge of plant genome editing technologies from all aspects of plant biology and agronomy as we move toward advancements in sustainable life research. The book will be highly recommended for agriculture biologists, agronomists, plant pathologists, and all related research areas.

This book summarizes the recent advancements for biomaterials in the field of cardiovascular disease, including drug delivery system (gene, protein, drug), implant interventional instrument (heart valve, heart blocker, stent, artificial blood vessel, patch, artificial heart, cardiac pacemaker, etc.) have been innovated and applied to the clinical uses to treatment of cardiovascular disease. Through the summary of this book, readers will have comprehensive and advanced understanding of the application of biomaterials in the field of cardiovascular disease.

Postbiotics: Health and Industry provides a detailed overview on the fundamentals, biological and therapeutic properties, safety, and application of postbiotics in health and industry. Sections cover the fundamentals of postbiotics, which include insights on probiotic microorganisms, postbiotics, and host–microbe interaction, analysis, and characterization of postbiotics. The book goes on to delve into the different types of postbiotics and their mechanisms. Remaining sections explore various health, pharmaceutical, and industrial applications of postbiotics. - Provides an overview on the separation, characterization, and identification of postbiotics from probiotic microbes - Includes classes of postbiotics and their mechanisms of action - Discusses the safety of postbiotics in humans and animals and the use of multiomics to understand the effect of postbiotics on human physiology - Analyzes existing regulatory framework for postbiotics

This book is a call to expand and diversify our approach to the study of the human mind in relation to the Theory of Mind. It proposes that it is necessary to combine cross-disciplinary methods to arrive at a more complete understanding of how our minds work. Seeking to expand the discussion surrounding the Theory of Mind beyond the field of psychology, and its focus on our capacity to ascribe mental states to other people, this volume collects evidence and research to point to a more holistic understanding of our own minds, the minds of others, behavior, language, and reasoning. This book therefore illuminates the conceptual intricacy underlying the Theory of Mind. It posits that a wide scope is necessary to make a breakthrough in scientific research towards a full understanding of the nature, function, and development of our capacity to converge on biological processes of the brain towards consciousness, emotion, awareness, and cognition. The volume presents methods, results, critiques, and models intended to provoke debates in various academic disciplines. It is of interest to scholars working in psychology, neuroscience, philosophy of mind, and artificial intelligence.

This book highlights recent advances focusing on the synthesis methods of engineered biomaterials and their applications. The book discusses recent applications of various approaches and technology in improving the functional properties and biological activities of biopolymers. It includes two major sections: the first section introduces a range of methods which lead to materials with enhanced properties for a range of practical applications, along with the positives and limitations of the techniques. The second section covers recent trends and advances in application of engineered biomaterials that assist materials scientists and researchers in mapping out the future of these new improved materials through value addition in order to enhance their use. Contributions in the book are done by prominent researchers from industry, academia, and government/private research laboratories across the globe. The book summarizes in a fairly comprehensive manner many of the recent technical advancements in the area of biopolymers. The book is intended to serve as a reference resource in the area of polymers science.

This book brings together the latest information on almond genomics and transcriptomics, with a particular focus on cutting-edge findings, tools, and strategies employed in genome sequencing and analysis with regard to the most important agronomic traits. Cultivated almond [(Prunus dulcis (Miller) D. A. Webb, syn. Prunus amygdalus Batsch., Amygdalus communis L., Amygdalus dulcis Mill.)] is a tree crop producing seeds of great economic interest, and adapted to hot and dry climates. Domesticated in Southeast Asia, its small diploid genome and phenotypic diversity make it an ideal model to complement genomics studies on peach, generally considered to be the reference Prunus species. Both represent consanguineous species that evolved in two distinct environments: warmer and more humid in the case of peach, and colder and xerophytic for almond. The advent of affordable whole-genome sequencing, in combination with existing Prunus functional genomics data, has now made it possible to leverage the novel diversity found in almond, providing an unmatched resource for the genetic improvement of this species.

Encyclopedia of Sensors and Biosensors, Four Volume Set provides unique foundational level information on the rapidly growing sensor community. The book covers innovations in materials, designs, devices and software that find their way into new types of sensors. Sections include over 1000 color images, including representations of sensor design, sensor manufacturing, and assessments of sensor performance. In addition, applications of sensors in healthcare, food safety, environmental engineering and other fields are discussed, making this a truly interdisciplinary work. The book is structured using a logical and thematic approach, with chapters taking a balanced viewpoint, listing both advantages and disadvantages. Perfect for those learning their trade in both academia and industry, this vital reference work will serve many groups, including chemists, engineers, biological scientists, clinicians, and industrial researchers. - Provides students and new scientists with a comprehensive,'one-stop'resource in sensor technology, giving them a solid grounding in unfamiliar topics - Presents the most up-to-date reference resource available, providing truly interdisciplinary coverage across all aspects of sensor technology - Ideal for researchers/scientists in both academia and industry - Allows experienced researchers to put their work into a broader context - Includes over 1000 color images that detail the full range of sensors and devices covered

Molecular Medical Microbiology, Third Edition presents the latest release in what is considered to be the first book to synthesize new developments in both molecular and clinical research. The molecular age has brought about dramatic changes in medical microbiology, along with great leaps in our understanding of the mechanisms of infectious disease. This third edition is completely updated, reviewed and expanded, providing a timely and helpful update for microbiologists, students and clinicians in the era of increasing use of molecular techniques, changing epidemiology and prevalence, and increasing resistance of many pathogenic bacteria. Written by experts in the field, chapters include cutting-edge information and clinical overviews for each major bacterial group, along with the latest updates on vaccine development, molecular technology and diagnostic technology. - Completely updated and revised edition of this comprehensive and accessible reference on molecular medical microbiology - Includes full color presentations throughout - Delves into in-depth discussions on individual pathogenic bacteria in a system-oriented approach - Includes a clinical overview for each major bacterial group - Presents the latest information on vaccine development, molecular technology and diagnostic technology - Provides more than 100 chapters on all major groups of bacteria

Under ongoing climate change, natural and cultivated habitats of major food crops are being continuously disturbed. Such condition accelerates to impose stress effects like abiotic and biotic stressors. Drought, salinity, flood, cold, heat, heavy metals, metalloids, oxidants, irradiation etc. are important abiotic stresses; and diseases and infections caused by plant pathogens viz. fungal agents, bacteria and viruses are major biotic stresses. As a result, these harsh environments affect crop productivity and its biology in multiple complex paradigms. As stresses become the limiting factors for agricultural productivity and exert detrimental role on growth and yield of the crops, scientists and researchers are challenged to maintain global food security for a rising world population.This two-volume work highlights the fast-moving agricultural research on crop improvement through the stress mitigation strategies, with specific focuses on crop biology and their response to climatic instabilities. Together with'Climate Resilient Agriculture, Vol 2: Agro-Biotechnological Advancement for Crop Production', it covers a wide range of topics under environmental challenges, agronomy and agriculture processes, and biotechnological approaches, uniquely suitable for scientists, researchers and students working in the fields of agriculture, plant science, environmental biology and biotechnology.

The careful choice of nanoparticles as targets and in drug delivery routes enhances therapeutic efficacy in cancer. Nanoparticle-Based Drug Delivery in Cancer Treatment discusses nanotechnological developments of interfering RNA-based nanoparticles, delivery vehicles, and validated therapeutic RNAi–molecular target interactions and explains the results of clinical and preclinical trials. The book also gives strategies for universal methods of constructing hybrid organic–inorganic nanomaterials that can be widely applied in the biomedical field. Key Features: Reviews recent advances of nanoparticle-mediated siRNA delivery systems and their application in clinical trials for cancer therapy Focuses on material platforms that establish NPs and both localized and controlled gene silencing Emphasizes the most promising systems for clinical application Surveys progress in nanoparticle-based nanomedicine in cancer treatment Describes the most advanced of the nonviral nanocarriers for delivery of oligonucleotides to malignant blood cancer cells This book is a valuable resource for researchers, professors, and students researching drug delivery, gene carriers, cancer therapy, nanotechnology, and nanomaterials.

The handbook comprehensively reviews the therapeutic potential of stem cells and stem cell secretome-based cell-free strategies in regenerative medicine. The chapters in section I and section II respectively discuss the diverse applications of mesenchymal stem cells and non- mesenchymal stem cells, including skeletal myoblasts, endothelial progenitor cells, adipose tissue-derived stem cells, induced pluripotent stem cells, and neuronal stem cells in myocardial repair, inflammatory bowel disease, cognitive deficits, wound healing, retinal disorders, and COVID-19. The subsequent chapters in section IIIprimarily focused on the fast-emerging cell-free therapy approach in regenerative medicine for tissue repair and regeneration. These chapters review the impact of stem cell-derived secretome on various biological processes such as angiogenesis, neurogenesis, tissue repair, immunomodulation, musculoskeletal pathologies, wound healing, anti-fibrotic, and anti-tumorigenesis for tissue maintenance and regeneration.Lastly, section IV summarizes miscellaneous aspects of cell-based therapy, includingthe treatment advantages, opportunities, and shortcomings in stem cell-based therapy, potentially helping to refine future studies and translate them from experimental to clinical studies. Moreover, this section also has chapters on cancer stem cells as novel targets in cancer therapeutics. This Major Reference Book (MRW) is a valuable resource for researchers involved in stem cell research to understand the multifaceted therapeutic applications of stem cells and their derivative secretome in regenerative medicine.​

This book discusses inorganic/metallic nanopesticides and fertilizers. Rather than providing a general review of the topic, it offers a critical assessment of what has been achieved and highlights future measures to allow agriculture to profit from the properties of inorganic nanoparticles. It covers a variety of topics, including strategies for preparing cost-effective nanoparticles, their chemistry both within and outside the plant, the effects of nanoparticles in the field and whether the current strategies were successful in increasing crop yields. This book will appeal to readers in academia and industry, as well as stakeholders and anyone who has an interest in the applications of inorganic nanopesticides and nanofertilizers as well as the potential use of these technologies in agriculture.

This book collates the latest trends and technological advancements in bioremediation, especially for its monitoring and assessment.Divided into 18 chapters, the book summarizes basic concepts of waste management and bioremediation, describes advancements of the existing technologies, and highlights the role of modern instrumentation and analytical methods, for environmental clean-up and sustainability.The chapters cover topics such as the role of microbial fuel cells in waste management, microbial biosensors for real-time monitoring of bioremediation processes, genetically modified microorganisms for bioremediation, application of immobilized enzyme reactors, spectroscopic techniques, and in-silico approaches in bioremediation monitoring and assessment. The book will be advantageous not only to researchers and scholars interested in bioremediation and sustainability but also to professionals and policymakers.

After the drug discovery and development process, designing suitable formulations to safely deliver the optimum dose, while avoiding side effects, has been a constant challenge, especially when drugs are very toxic and have poor solubility and undesirable clearance profiles. With recent advances in synthetic technologies, nanoparticles can be custom-made from a variety of advanced materials to mimic the bioenvironment and can be equipped with various targeting and imaging moieties for site-specific delivery and real-time imaging. Drug Delivery Using Nanomaterials covers advancements in the field of nanoparticle-based drug-delivery systems, along with all the aspects needed for a successful and marketable nanoformulation.FEATURES Offers a general overview of the entire process involved in the synthesis and characterization of pharmaceutical nanoparticles Covers a broad range of synthetic materials for developing nanoformulations customized for specific disease states, target organs, and drugs Every chapter sequentially builds, providing a progressive pathway from classical nanoparticles to the more advanced to be used as a full drug product by consumers Provides information in a bottom-up manner in that definitions and explanations of relevant background information serve as a framework for understanding advanced concepts This user-friendly reference is aimed at materials engineers, chemical engineers, biomedical engineers, pharmaceutical scientists, chemists, and others working on advanced drug delivery, from academia as well as industry.

Volume 1:Biofabrication aims to produce artificially manufactured tissues and organs, potentially revolutionizing conventional paradigm of clinical practice in treating diseases and extending the life span and quality of human beings. In this volume, we invite notable experts in the field of biofabrication and biomanufacturing to summarize recent rapid progress in this field from multifaceted aspects covering biofabrication techniques and building materials such as scaffold and living cells. Specifically, a focus is placed on a variety of techniques derived from 3D bioprinting and bioassembly strategies, such as acoustic assembly and electrofabrication. Moreover, principles and strategies for choosing hydrogels and polymers for biofabrication are also heavily discussed. Overall, this book creates a good opportunity for undergraduate and postgraduate students as well as bioengineers and medical researchers who wish to gain a fundamental understanding of current status and future trends in biofabrication and biomanufacturing.Volume 2:Infertility has become a significant psychosocial burden affecting the lives of couples who cannot reproduce naturally. Advanced reproductive technologies (ARTs) are being developed to treat infertility. This handbook explores significant development of ARTs for fertility testing, selection of sperm, oocyte and embryo, reproductive monitors, automation in embryology, and fertility preservation. This volume provides a comprehensive overview of the myriad of emerging technologies and systems that are being utilized or will be utilized in near future in reproductive clinics. Overall this book creates a good opportunity for undergraduate and postgraduate students as well as scientists and medical researchers who wish to gain fundamental understanding of current status and future trends in fertility and reproductive medicine.Volume 3:Healthcare industry has a notable paradigm transition from centralized care to the point-of-care (POC). During this metamorphosis, a number of new technologies and strategies have been adapted to the current practice, addressing the existing challenges in the fields of medicine and biology. All the efforts aim to improve the clinical management and the effectiveness and quality of care. In particular, diagnostics has pivotal roles in guiding clinical management for the most effective treatment to control and cure the disease. In contrast to the existing diagnostic strategies employing bulky-sized tools, expensive infrastructure, laborious protocols, and lengthy processing steps, the contribution of biosensors to current healthcare system, especially to diagnostics, is paramount. The unprecedented and admirable characteristics of biosensing strategies have expanded our knowledge on medicine and biology by harmonizing materials science, chemistry, physics, and engineering. We believe that biosensors applied to disease diagnostics will not only garner more attention in clinical research to decipher disease biology and mechanism, and also, stimulate innovative perspectives in artificial intelligence (AI) and internet of things (IoT) synergistically, thereby their more facile adaptation to daily-use. Overall this book creates a good opportunity for undergraduate and postgraduate students as well as scientists and medical researchers who wish to gain fundamental understanding of current status and future trends in diagnostic technologies.

Industrial microbiology utilizes microorganisms to produce industrially important products in a more sustainable way, as opposed to the traditional chemical and energy intensive processes. The present book is an attempt to provide its readers with compiled and updated information in the area of Industrial Microbiology and Biotechnology. This book provides the basics of microbiology and how it has been exploited at an industrial scale. The book focuses on the role of biotechnological advances that directly impact the industrial production of several bioactive compounds using microbes-based methods under a controlled and regulated environment. On one hand, this book presents detailed information on the basics of microbiology such as types of microbes and their applications, bioreactor design, fermentation techniques, strain improvement strategies, etc. At the same time it also provides recent and updated information on industrial production, recovery, and applications of enzymes, alcohols, organic acids, steroids as a drug precursor, etc., using microbial biotechnological approaches. The book presents an overview of modern technological advances for the generation of energy (biomethane, bioethanol, and bioelectricity) and resource recovery from waste. It also highlights the application of CRISPR-based technologies in the industrial microbiology sector. This book is developed with the motive to benefit students, academicians, as well as researchers. The book will also find interests among microbiologists, biotechnologists, environmentalists, and engineers working in the application of the microbes-based approach for the development of greener technologies.

Nanomaterials in Bionanotechnology: Fundamentals and Applications offers a comprehensive treatment of nanomaterials in biotechnology from fundamentals to applications, along with their prospects. This book explains the basics of nanomaterial properties, synthesis, biological synthesis, and chemistry and demonstrates how to use nanomaterials to overcome problems in agricultural, environmental, and biomedical applications. Features Covers nanomaterials for environmental analysis and monitoring for heavy metals, chemical toxins, and water pollutant detection Describes nanomaterials-based biosensors and instrumentation and use in disease diagnosis and therapeutics Discusses nanomaterials for food processing and packaging and agricultural waste management Identifies challenges in nanomaterials-based technology and how to solve them This work serves as a reference for industry professionals, advanced students, and researchers working in the discipline of bionanotechnology.

This book aims to comprehensively summarize the current research status of nanomaterials and cell biology. It highlights the biological effects and biomedical applications of nanomaterials for specific diseases, bone tissue engineering, and skeletal muscle regeneration. It also provides the details of the biomedical applications of nucleic acid nanomaterials in drug delivery carriers, antimicrobial therapy, vaccine, and neurodegenerative diseases. Therefore, this book renders the audience a better understanding of nanomaterials along with the diverse applications in the cell biology field from recent works to perspectives.

Fungi range from being microscopic, single-celled yeasts to multicellular and heterotrophic in nature. Fungal communities have been found in vast ranges of environmental conditions. They can be associated with plants epiphytically, endophytically, or rhizospherically. Extreme environments represent unique ecosystems that harbor novel biodiversity of fungal communities. Interest in the exploration of fungal diversity has been spurred by the fact that fungi perform numerous functions integral in sustaining the biosphere, ranging from nutrient cycling to environmental detoxification, which involves processes like augmentation, supplementation, and recycling of plant nutrients--a particularly important process in sustainable agriculture. Fungal communities from natural and extreme habitats help promote plant growth, enhance crop yield, and soil fertility via direct or indirect plant growth promoting (PGP) mechanisms of solubilization of phosphorus, potassium, and zinc, production of ammonia, hydrogen cyanides, phytohormones, Fe-chelating compounds, extracellular hydrolytic enzymes, and bioactive secondary metabolites. These PGP fungi could be used as biofertilizers, bioinoculants, and biocontrol agents in place of chemical fertilizers and pesticides in eco-friendly manners for sustainable agriculture and environments. Along with agricultural applications, medically important fungi play significant role for human health. Fungal communities are useful for sustainable environments as they are used for bioremediation which is the use of microorganisms'metabolism to degrading waste contaminants (sewage, domestic, and industrial effluents) into non-toxic or less toxic materials by natural biological processes. Fungi could be used as mycoremediation for the future of environmental sustainability. Fungi and fungal products have the biochemical and ecological capability to degrade environmental organic chemicalsand to decrease the risk associated with metals, semi-metals, and noble metals either by chemical modification or by manipulating chemical bioavailability. The two volumes of'Recent Trends in Mycological Research” aim to provide an understanding of fungal communities from diverse environmental habitats and their potential applications in agriculture, medical, environments and industry. The books are useful to scientists, researchers, and students involved in microbiology, biotechnology, agriculture, molecular biology, environmental biology and related subjects.

Nanosensors are innovative devices that exploit the unique properties exhibited by matter at the nanoscale. A growing and exciting field, nanosensors have recently spurred considerable research endeavors across the globe, driving a need for the development of new device concepts and engineering nanostructured materials with controlled properties. Nanosensors: Physical, Chemical, and Biological, Second Edition offers a panoramic view of the field and related nanotechnologies with extraordinary clarity and depth.Presenting an interdisciplinary approach, blending physics, chemistry and biology, this new edition is broad in scope and organised into six parts; beginning with the fundamentals before moving onto nanomaterials and nanofabrication technologies in the second part. The third and fourth parts provide a critical appraisal of physical nanosensors, and explore the chemical and biological categories of nanosensors. The fifth part sheds light on the emerging applications of nanosensors in the sectors of society, industry, and defense and details the cutting-edge applications of state-of-the-art nanosensors in environmental science, food technology, medical diagnostics, and biotechnology. The final part addresses self-powering and networking issues of nanosensors, and provides glimpses of future trends.This is an ideal reference for researchers and industry professionals engaged in the frontier areas of material science and semiconductor fabrication as well as graduate students in physics and engineering pursuing electrical engineering and electronics courses with a focus on nanoscience and nanotechnology.Key features: Provides an updated, all-encompassing exploration of contemporary nanosensors and highlights the exclusive nanoscale properties on which nanosensors are designed. Presents an accessible approach with a question-and-answer format to allow an easy grasp of the intricacies involved in the complex working mechanisms of devices. Contains clear, illustrative diagrams enabling the visualization of nanosensor operations, along with worked examples, end of chapter questions, and exhaustive up-to-date bibliographies appended to each chapter.

Data Analytics in Biomedical Engineering and Healthcare explores key applications using data analytics, machine learning, and deep learning in health sciences and biomedical data. The book is useful for those working with big data analytics in biomedical research, medical industries, and medical research scientists. The book covers health analytics, data science, and machine and deep learning applications for biomedical data, covering areas such as predictive health analysis, electronic health records, medical image analysis, computational drug discovery, and genome structure prediction using predictive modeling. Case studies demonstrate big data applications in healthcare using the MapReduce and Hadoop frameworks. - Examines the development and application of data analytics applications in biomedical data - Presents innovative classification and regression models for predicting various diseases - Discusses genome structure prediction using predictive modeling - Shows readers how to develop clinical decision support systems - Shows researchers and specialists how to use hybrid learning for better medical diagnosis, including case studies of healthcare applications using the MapReduce and Hadoop frameworks

Deep learning, a branch of Artificial Intelligence and machine learning, has led to new approaches to solving problems in a variety of domains including data science, data analytics and biomedical engineering. Deep Learning for Data Analytics: Foundations, Biomedical Applications and Challenges provides readers with a focused approach for the design and implementation of deep learning concepts using data analytics techniques in large scale environments. Deep learning algorithms are based on artificial neural network models to cascade multiple layers of nonlinear processing, which aids in feature extraction and learning in supervised and unsupervised ways, including classification and pattern analysis. Deep learning transforms data through a cascade of layers, helping systems analyze and process complex data sets. Deep learning algorithms extract high level complex data and process these complex sets to relatively simpler ideas formulated in the preceding level of the hierarchy. The authors of this book focus on suitable data analytics methods to solve complex real world problems such as medical image recognition, biomedical engineering, and object tracking using deep learning methodologies. The book provides a pragmatic direction for researchers who wish to analyze large volumes of data for business, engineering, and biomedical applications. Deep learning architectures including deep neural networks, recurrent neural networks, and deep belief networks can be used to help resolve problems in applications such as natural language processing, speech recognition, computer vision, bioinoformatics, audio recognition, drug design, and medical image analysis. - Presents the latest advances in Deep Learning for data analytics and biomedical engineering applications. - Discusses Deep Learning techniques as they are being applied in the real world of biomedical engineering and data science, including Deep Learning networks, deep feature learning, deep learning toolboxes, performance evaluation, Deep Learning optimization, deep auto-encoders, and deep neural networks - Provides readers with an introduction to Deep Learning, along with coverage of deep belief networks, convolutional neural networks, Restricted Boltzmann Machines, data analytics basics, enterprise data science, predictive analysis, optimization for Deep Learning, and feature selection using Deep Learning

Presents nanobiotechnology in drug delivery and disease management Featuring contributions from noted experts in the field, this book highlights recent advances in the nano-based drug delivery systems. It also covers the diagnosis and role of various nanomaterials in the management of infectious diseases and non-infectious disorders, such as cancers and other malignancies and their role in future medicine. Nanobiotechnology in Diagnosis, Drug Delivery and Treatment starts by introducing how nanotechnology has revolutionized drug delivery, diagnosis, and treatments of diseases. It then focuses on the role of various nanocomposites in diagnosis, drug delivery, and treatment of diseases like cancer, Alzheimer's disease, diabetes, and many others. Next, it discusses the application of a variety of nanomaterials in the diagnosis and management of gastrointestinal tract disorders. The book explains the concept of nanotheranostics in detail and its role in effective monitoring of drug response, targeted drug delivery, enhanced drug accumulation in the target tissues, sustained as well as triggered release of drugs, and reduction in adverse effects. Other chapters cover aptamer-incorporated nanoparticle systems; magnetic nanoparticles; theranostics and vaccines; toxicological concerns of nanomaterials used in nanomedicine; and more. Provides a concise overview of state-of-the-art nanomaterials and their application like drug delivery in infectious diseases and non-infectious disorders Highlights recent advances in the nano-based drug delivery systems and role of various nanomaterials Introduces nano-based sensors which detect various pathogens Covers the use of nanodevices in diagnostics and theranostics Nanobiotechnology in Diagnosis, Drug Delivery and Treatment is an ideal book for researchers and scientists working in various disciplines such as microbiology, biotechnology, nanotechnology, pharmaceutical biotechnology, pharmacology, pharmaceutics, and nanomedicine.

Plants have been a source of medicines and have played crucial role for human health. Despite tremendous advances in the field of synthetic drugs and antibiotics, plants continue to play a vital role in modern as well as traditional medicine across the globe. In even today, one-third of the world's population depends on traditional medicine because of its safety features and ability to effectively cure diseases. This book presents a comprehensive guide to medicinal plants, their utility, diversity and conversation, as well as biotechnology. It is divided into four main sections, covering all aspects of research in medicinal plants: biodiversity and conservation; ethnobotany and ethnomedicine; bioactive compounds from plants and microbes; and biotechnology. All sections cover the latest advances. The book offers a valuable asset for researchers and graduate students of biotechnology, botany, microbiology and the pharmaceutical sciences. It is an equally important resource for doctors (especially those engaged in Ayurveda and allopathy); the pharmaceutical industry (for drug design and synthesis); and the agricultural sciences.

Deep Learning Techniques for Biomedical and Health Informatics provides readers with the state-of-the-art in deep learning-based methods for biomedical and health informatics. The book covers not only the best-performing methods, it also presents implementation methods. The book includes all the prerequisite methodologies in each chapter so that new researchers and practitioners will find it very useful. Chapters go from basic methodology to advanced methods, including detailed descriptions of proposed approaches and comprehensive critical discussions on experimental results and how they are applied to Biomedical Engineering, Electronic Health Records, and medical image processing. - Examines a wide range of Deep Learning applications for Biomedical Engineering and Health Informatics, including Deep Learning for drug discovery, clinical decision support systems, disease diagnosis, prediction and monitoring - Discusses Deep Learning applied to Electronic Health Records (EHR), including health data structures and management, deep patient similarity learning, natural language processing, and how to improve clinical decision-making - Provides detailed coverage of Deep Learning for medical image processing, including optimizing medical big data, brain image analysis, brain tumor segmentation in MRI imaging, and the future of biomedical image analysis

Comprehensive Foodomics, Three Volume Set offers a definitive collection of over 150 articles that provide researchers with innovative answers to crucial questions relating to food quality, safety and its vital and complex links to our health. Topics covered include transcriptomics, proteomics, metabolomics, genomics, green foodomics, epigenetics and noncoding RNA, food safety, food bioactivity and health, food quality and traceability, data treatment and systems biology. Logically structured into 10 focused sections, each article is authored by world leading scientists who cover the whole breadth of Omics and related technologies, including the latest advances and applications. By bringing all this information together in an easily navigable reference, food scientists and nutritionists in both academia and industry will find it the perfect, modern day compendium for frequent reference. List of sections and Section Editors: Genomics - Olivia McAuliffe, Dept of Food Biosciences, Moorepark, Fermoy, Co. Cork, Ireland Epigenetics & Noncoding RNA - Juan Cui, Department of Computer Science & Engineering, University of Nebraska-Lincoln, Lincoln, NE Transcriptomics - Robert Henry, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St Lucia, Australia Proteomics - Jens Brockmeyer, Institute of Biochemistry and Technical Biochemistry, University Stuttgart, Germany Metabolomics - Philippe Schmitt-Kopplin, Research Unit Analytical BioGeoChemistry, Neuherberg, Germany Omics data treatment, System Biology and Foodomics - Carlos Leon Canseco, Visiting Professor, Biomedical Engineering, Universidad Carlos III de Madrid Green Foodomics - Elena Ibanez, Foodomics Lab, CIAL, CSIC, Madrid, Spain Food safety and Foodomics - Djuro Josic, Professor Medicine (Research) Warren Alpert Medical School, Brown University, Providence, RI, USA & Sandra Kraljevic Pavelic, University of Rijeka, Department of Biotechnology, Rijeka, Croatia Food Quality, Traceability and Foodomics - Daniel Cozzolino, Centre for Nutrition and Food Sciences, The University of Queensland, Queensland, Australia Food Bioactivity, Health and Foodomics - Miguel Herrero, Department of Bioactivity and Food Analysis, Foodomics Lab, CIAL, CSIC, Madrid, Spain Brings all relevant foodomics information together in one place, offering readers a ‘one-stop,'comprehensive resource for access to a wealth of information Includes articles written by academics and practitioners from various fields and regions Provides an ideal resource for students, researchers and professionals who need to find relevant information quickly and easily Includes content from high quality authors from across the globe

This book fills the gap between fundamental and applied research in the use of nanomaterials in biomedical applications, covering the most relevant areas, such as the fundamental concepts of the preparation of nanostructures and regulatory requirements for their safe use in biomedical devices. It also critically discusses what has been achieved in the field, and what needs to be urgently addressed and reviews the state-of-the-art medical uses of nanomaterials for treating damaged organs and tissues.Combining the expertise of clinical researchers working in the field of tissue engineering and novel materials, the book explores the main topics regarding the characterization of materials, specific organ-oriented biomaterials and their applications, as well as regulations and safety. Further, it also examines recent advances, difficulties, and clinical requirements in terms of human bone, cornea, heart, skin and the nervous system, allowing readers to gain a clear and comprehensive understanding of current nanomaterial use in biomedical applications and devices, together with the challenges and future trends.This book is a valuable tool for multidisciplinary scientists and experts interested in fundamental concepts and synthetic routes for preparing nanomaterials. It is also of interest to students and researchers involved in cross-disciplinary research in nanomaterials for clinical applications and offers practical insights for clinicians as well as engineers and materials scientists working in nanoengineering.

Biotechnology can be defined as the manipulation of biological process, systems, and organisms in the production of various products. With applications in a number of fields such as biomedical, chemical, mechanical, and civil engineering, research on the development of biologically inspired materials is essential to further advancement. Biotechnology: Concepts, Methodologies, Tools, and Applications is a vital reference source for the latest research findings on the application of biotechnology in medicine, engineering, agriculture, food production, and other areas. It also examines the economic impacts of biotechnology use. Highlighting a range of topics such as pharmacogenomics, biomedical engineering, and bioinformatics, this multi-volume book is ideally designed for engineers, pharmacists, medical professionals, practitioners, academicians, and researchers interested in the applications of biotechnology.

White biotechnology is industrial biotechnology dealing with various biotech products through applications of microbes. The main application of white biotechnology is commercial production of various useful organic substances, such as acetic acid, citric acid, acetone, glycerine, etc., and antibiotics like penicillin, streptomycin, mitomycin, etc., and value added product through the use of microorganisms especially fungi and bacteria. The value-added products included bioactive compounds, secondary metabolites, pigments and industrially important enzymes for potential applications in agriculture, pharmaceuticals, medicine and allied sectors for human welfare. In the 21st century, techniques were developed to harness fungi to protect human health (through antibiotics, antimicrobial, immunosuppressive agents, value-added products etc.), which led to industrial scale production of enzymes, alkaloids, detergents, acids, biosurfactants. The first large-scale industrial applications of modern biotechnology have been made in the areas of food and animal feed production (agricultural/green biotechnology) and pharmaceuticals (medical/red biotechnology). In contrast, the production of bio-active compounds through fermentation or enzymatic conversion is known industrial or white biotechnology. The beneficial fungal strains may play important role in agriculture, industry and the medical sectors. The beneficial fungi play a significance role in plant growth promotion, and soil fertility using both, direct (solubilization of phosphorus, potassium and zinc; production of indole acetic acid, gibberellic acid, cytokinin and siderophores) and indirect (production of hydrolytic enzymes, siderophores, ammonia, hydrogen cyanides and antibiotics) mechanisms of plant growth promotion for sustainable agriculture. The fungal strains and their products (enzymes, bio-active compounds and secondary metabolites) are very useful for industry. The discovery of antibiotics is a milestone in the development of white biotechnology. Since then, white biotechnology has steadily developed and now plays a key role in several industrial sectors, providing both high valued nutraceuticals and pharmaceutical products. The fungal strains and bio-active compounds also play important role in the environmental cleaning. This volume covers the latest research developments related to value-added products in white biotechnology through fungi.

Fungal nanobionics has great prospects for developing new products with industrial, agriculture, medicine and consumer applications in a wide range of sectors. The fields of chemical engineering, agri-food, biochemical, pharmaceuticals, diagnostics and medical device development all employ fungal products, with fungal nanomaterials currently used in a wide range of applications, ranging from drug development to food industry and agricultural sector. The fungal agents emerge as an environmentally friendly, clean, non‐toxic agent for the biogenic metal nanoparticles and employs both intracellular and extracellular methods. The simplicity of scaling up and downstream processing and the presence of fungal mycelia affording an increased surface area provide key advantages. In addition, the larger spectrum of synthesized nanoparticle morphologies and the substantially faster biosynthesis rate in cell-free filtrate (due to the higher amount of proteins secreted in fungi) make this a particularly enticing route. Understanding the diversity of fungi in assorted ecosystems, as well as their interactions with other microorganisms, animals and plants, is essential to underpin real and innovative technological developments and the applications of metal nanoparticles in many disciplines including agriculture, catalysis, and biomedical biosensors. Importantly, biogenic fungal nanoparticles show significant synergistic characteristics when combined with antibiotics and fungicides to offer substantially greater resistance to microbial growth and applications in nanomedicine ranging from topical ointments and bandages for wound healing to coated stents.

Nature, by dint of its constitution, harbors many unassuming mysteries broadly manifested by its constituent cohorts. If physics is the pivot that holds nature and chemistry provides reasons for its existence, then the rest is just manifestation. Nanoscience and technology harbor the congruence of these two core subjects, whereby many phenomenon may be studied in the same perspective. That nature operates at nanoscale—obeying the principles of thermodynamics and supramolecular chemistry—is a well understood fact manifested in a variety of life processes: bones are restored after a fracture; clots potentially leading to cerebral strokes can be dissolved. The regeneration of new structures in our system follows a bottom-up approach. Be it a microbe (benign or pathogenic), plant (lower or higher), plant parts/organs, food beneficiaries, animal (lower), higher animal processing wastes, these all are found to deliver nanomaterials under amenable processing conditions. Identically, the molecules also seem to obey the thermodynamic principles once they get dissociated/ionized and the energy captured in the form of bonding helps in the synthesis of a myriad of nanomaterials. This edited volume explores the various green sources of nanomaterial synthesis and evaluates their industrial and biomedical applications with a scope of scaling up. It provides useful information to researchers involved in the green synthesis of nanomaterials in fields ranging from medicine to integrated agricultural management.

This book combines the contributions from the experts of material science, molecular biology, toxicology bio-organic and bio-inorganic chemistry, toxicologists and environmental and food technology etc. to fathom the full scope of current and future of developments in the area of Nanobiotechnology. Provides brief overview of nanobiotechnology for general readers who are not familiar with the research fields and presents a strong overview of most of the critical areas in fieldThis book can also be used as text book for graduate students as an essential reference material, and as an reading material for general readers having a curiosity in Nanobiotechnology.

In recent years there has been tremendous progress in the area of tissue engineering research. This book focusses on the fundamental principles underpinning these recent advances in the materials science developed for tissue engineering purposes. Smart materials for tissue engineering are produced by modifying the physicochemical and biological properties of the scaffolds with response to external stimuli to enhance the tissue regeneration. The functions of living cells can be regulated by smart materials which respond to changes in the surrounding microenvironment. This book comprehensively documents the recent advancements in smart materials for tissue engineering and will provide an essential text for those working in materials science and materials engineering, in academia and industry.

Millions of patients suffer from end-stage organ failure or tissue loss annually, and the only solution might be organ and/or tissue transplantation. To avoid poor biocompatibility–related problems and donor organ shortage, however, around 20 years ago a new, hybridized method combining cells and biomaterials was introduced as an alternative to whole-organ and tissue transplantation for diseased, failing, or malfunctioning organs—regenerative medicine and tissue engineering. This handbook focuses on all aspects of intelligent scaffolds, from basic science to industry to clinical applications. Its 10 parts, illustrated throughout with excellent figures, cover stem cell engineering research, drug delivery systems, nanomaterials and nanodevices, and novel and natural biomaterials. The book can be used by advanced undergraduate- and graduate-level students of stem cell and tissue engineering and researchers in macromolecular science, ceramics, metals for biomaterials, nanotechnology, chemistry, biology, and medicine, especially those interested in tissue engineering, stem cell engineering, and regenerative medicine.

Nanomedicine-the application of nanotechnology to health sciences-has the potential to address many important medical problems by exploiting the advanced physicochemical characteristics of nanostructured materials and devices. It can revolutionize conventional medicine by offering cutting-edge developments in the processes of diagnosing, treating,

This comprehensive volume provides the reader valuable insight into the major areas of biomedical nanomaterials, advanced nanomedicine, nanotheragnostics, and cutting-edge nanoscaffolds. The ability to control the structure of materials allows scientists to accomplish what once appeared impossible before the advent of nanotechnology. It is now possible to generate nanoscopic self-assembled and self-destructive robots for effective utilization in therapeutics, diagnostics, and biomedical implants. Nanoscopic therapeutic systems incorporate therapeutic agents, molecular targeting, and diagnostic imaging capabilities and they have emerged as the next generation of multifarious nanomedicine to improve the therapeutic outcome including chemo and translational therapy. Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering comprises fifteen chapters authored by senior scientists, and is one of the first books to cover nanotheragnostics, which is the new developmental edge of nanomedicine combining both diagnostic and therapeutic elements at the nano level. This large multidisciplinary reference work has four main parts: biomedical nanomaterials; advanced nanomedicine; nanotheragnostics; and nanoscaffolds technology. This groundbreaking volume also covers: Multifunctional polymeric nanostructures for therapy and diagnosis Metalla-assemblies acting as drug carriers Nanomaterials for management of lung disorders and drug delivery Responsive polymer-inorganic hybrid nanogels for optical sensing, imaging, and drug delivery Core/shell nanoparticles for drug delivery and diagnosis Theranostic nanoparticles for cancer imaging and therapy Magnetic nanoparticles in tissue regeneration Core-sheath fibers for regenerative medicine

Biomedical Materials and Diagnostics Devices provides an up-to-date overview of the fascinating and emerging field of biomedical materials and devices, fabrication, performance, and uses The biomedical materials with the most promising potential combine biocompatibility with the ability to adjust precisely the biological phenomena in a controlled manner. The world market for biomedical and diagnostic devices is expanding rapidly and the pace of academic research resulted in about 50,000 published papers in recent years. It is timely, therefore, to assemble a volume on this important subject. The chapters in the book seek to address progress in successful design strategies for biomedical materials and devices such as the use of collagen, crystalline calcium orthophosphates, amphiphilic polymers, polycaprolactone, biomimetic assembly, bio-nanocomposite matrices, bio-silica, theranostic nanobiomaterials, intelligent drug delivery systems, elastomeric nanobiomaterials, electrospun nano-matrices, metal nanoparticles, and a variety of biosensors. This large and comprehensive volume includes twenty chapters authored by some of the leading researchers in the field, and is divided into four main areas: biomedical materials; diagnostic devices; drug delivery and therapeutics; and tissue engineering and organ regeneration.