One of the hitherto little researched phenomena of Late Middle Ages is the cult of the Fourteen Holy Helpers, which was distinctly influencing the spiritual climate of Central Europe from the thirteenth to the sixteenth century. Initially the cult covering a variable group, composed largely of male and female saints of Christian Antiquity, intensively spread, since the fourteenth century, from its center between Krems, Passau, Regensburg, and Brixen into additional Austrian, Bavarian, and Franconian regions. The cult gained a definite anchorage on the basis of an alleged revelation of Child Jesus and the Fourteen Holy Helpers, which occurred in 1445/1446 on the grounds of the Cistercian Abbey Langheim in the Bamberg Diocese of Upper Franconia. From that moment – when also the famous pilgrimage place of Vierzehnheiligen sprang up – the cult rapidly expanded in all directions so that by the time of the European Reformations it extended on a vast territory from Denmark to Italy, and from France to Hungary. Moreover, more than any other similar cults, it attracted the interest of social elites, including the aristocratic and intellectual ones. The dissertation is thematically divided into five chapters, representing studies which, while distinctive, yet naturally relate to each other. The first one aims at the Austro‑Bavarian area, a specific cultural region of Central Europe, and the focal point of the cult of the Fourteen Holy Helpers. The following three chapters analyze the functions of the principal pilgrimage centers of the cult. In the first place, it is an exploration of the Vierzehnheiligen in Upper Franconia, where in mid‑fifteenth century there arose a pilgrimage site with an almost unexpected Christocentric spirituality, which attracted members of contemporary elites. This inspiration led to the creation of Vierzehnheiligen cult also in Thuringia that became a sort of spiritual, as well as a combined ecclesiastical and political center of the Saxon dynasty of the Wettins. Finally, there emerged a pilgrimage site in the North‑Western Bohemian Kadaň, where the principal point of attraction was the Franciscan church of the Fourteen Holy Helpers, supported by the aristocratic family of the Hasištejnskýs of Lobkowicz. A separate chapter is devoted to the expansion of the cult into other European regions, and especially to the selection of artefacts, representing the noted Christocentric dimension of this phenomenal cult. The monograph is conceived to be interdisciplinary with a wide utilization of literary and iconographic material of Central Europe, broadly conceived. The structural analysis thoroughly explores the various aspects of the cult of the Fourteen Holy Helpers, which has appeared as a significant phenomenon of the last three medieval centuries, in its last phase even spilling over into the early modern times. One of the key results of the analytical exploration – which at the same time attempts a synthesis – is above all a new periodization of the earliest history of the cult, which, during the course of the research, naturally resulted into four mutually sequential temporal phases. The years 1250–1280 till 1350 can be rightfully designated as a period of incubation, when the cult of the Fourteen Holy Helpers had its gradual start and development in the Austro‑Bavarian area, above all in Bavaria and in Tirol. Apparently on the initiative of mendicant preachers – Minorites and Dominicans – with the support of relevant episcopal authorities in Passau, Regensburg, and Brixen, there gradually came together a group of specially privileged saints, both male and female, and mainly martyrs of Christian Antiquity. Their cult served vis‑à‑vis the rising Christian non‑conformism, particularly Waldensianism, as an instrument of discipline and of deepened internalized Christianity for the local population. The imperial and episcopal town of Regensburg proved to be the initial focus of the cult of the Fourteen Holy Helpers. T