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Substance misuse and addictions are a public health issue. They affect the well-being of each community and nation as a whole. It is, therefore, necessary to identify, educate, and treat individuals who are addicted to substances. Policies and procedures go hand-in-hand with public health education and safety. The science behind the public health issues of one drug may be applicable to other drugs as well. However, marshalling all of the aforementioned information into a single source is somewhat difficult due to the wide array of material. The Editors address this by compiling the research in this single reference work that serves as a'one-stop-shopping'approach to everything readers need to know about the scientific basis of public health and addictions and agents of misuse.Apart from active agents that have a plant or chemical basis, there is a need to consider that there are other forms of addiction which may havecommon modes of causality or prevention. These include food addiction, gaming, gambling, and other non-drug addictions. These types of addiction may be related to the addiction of drugs.The Handbook of Substance Misuse and Addictions: From Biology to Public Health offers a holistic understanding of the relationship between public health and substance misuse. The text provides a common platform upon which other forms of addiction or substance misuse can be understood and treated. Addiction processes involve understanding the biological processes as well as behavior, psychology, sociology, and public health, all of which are interlinked. This Handbook is a useful reference for lecturers, students, researchers, practitioners, and other professionals in public health, addiction science, epidemiology, health education, health promotion, and health sciences.

Comprehensive Clinical Psychology, Second Edition, 11 Volume Set brings together important information in the field, making this reference a current state-of-the-art of contemporary research and discussion. The book covers foundational history, professional and training issues, clinical research considerations and methods, assessments and treatments for clinical conditions experienced across the lifespan, clinical considerations for diverse populations, and emerging trends and future directions. In addition, this new release focuses on key areas, such as the emergence of new professional and training issues, new research and statistical approaches to clinical psychology, changes to the manner in which various mental health conditions are conceptualized, and more. Readers will find this to be an ideal, one-stop, comprehensive resource in clinical psychology that is thoroughly modernized to include all recent advances in the field. - Provides an update to this much-loved classic reference work with all the scientific advances of the past 20 years - Presents comprehensive and authoritative articles on all aspects of clinical psychology - Offers readers a'one-stop'resource for access to a wealth of information that will fully support their research and activities - Written by leading experts in psychology across the globe, thus ensuring the knowledge within is easily understood by, and applicable to, a large audience

Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this growing area of psychiatry. This new edition has been fully revised to address recent advances in epigenetic understanding of psychiatric disorders, evoking data consortia (e.g., CommonMind, ATAC-seq), single cell analysis, and epigenome-wide association studies to empower new research. The book also examines epigenetic effects of the microbiome on psychiatric disorders, and the use of neuroimaging in studying the role of epigenetic mechanisms of gene expression. Ongoing advances in epigenetic therapy are explored in-depth. - Fully revised to discuss new areas of research across neuronal stem cells, cognitive disorders, and transgenerational epigenetics in psychiatric disease - Relates broad advances in psychiatric epigenetics to a modern understanding of the genome, transcriptome, and proteins - Catalyzes knowledge discovery in both basic epigenetic biology and epigenetic targets for drug discovery - Provides guidance in research methods and protocols, as well how to employ data from consortia, single cell analysis, and epigenome-wide association studies (EWAS) - Features chapter contributions from international leaders in the field

Major depressive disorder (MDD) is a serious, debilitating, life-shortening illness that affects many persons of all ages and backgrounds. The lifetime risk for MDD is 7-12% for men and 20-25% for women (Kessler et al., 2003). MDD is a disabling disorder that costs the U.S. over $200 billion per year in direct and indirect costs (Greenberg et al., 2015), and is the leading cause of disability worldwide (WHO, 2018). Depression also has detrimental effects on all aspects of social functioning (e.g., self-care, social role, and family life, including household, marital, kinship, and parental roles). While there have been several treatments that are efficacious, many individuals suffering from depression experience life-long challenges due to the chronic and episodic nature of the disease. Identifying strategies to find the right treatments for the right patients is critical. Ongoing research has explored the importance of examining physiologic biomarkers, as well as clinical characteristics to gain a better understanding of subtypes of depression, which will lead to improved treatments and better outcomes. This book provides an introduction to the etiology and pathophysiology of depression, common comorbidities and differential diagnoses, pharmacotherapy strategies, psychotherapeutic and neuromodulation interventions, novel and non-traditional treatment strategies, and considerations in special populations.

Psychopathology, Fifth Edition is the most up-to-date text about the etiology and treatment of the most important psychological disorders. The chapters are written by leading experts in the field of psychopathology who provide up-to-date information on theory, research, and clinical practice. The book is unique in its strong emphasis on critical thinking about psychopathology as represented by chapters on such topics as culture, race, gender, class, clinical judgment and decision-making, and alternatives to traditional categorical approaches to understanding psychopathology. The contributors have incorporated information about and from the World Health Organization's International Classification of Diseases along with information about and from the DSM-5.As with the previous editions, this book remains a true textbook in psychopathology. Unlike the many weighty volumes that are intended as reference books, Psychopathology, Fifth Edition has been designed specifically to serve as a textbook on psychopathology for graduate students in clinical and counseling psychology programs and related programs such as social work. It will also serve as an extremely useful reference source for practitioners and researchers.

This book will help the reader to understand the suicidal mind from a phenomenological point of view, shedding light on the feelings of suicidal individuals and also those of clinicians. In accordance with the importance that the phenomenological approach attaches to subjectivity and sense of self as the starting points for knowledge, emphasis is placed on the need for the clinician to focus on the subjective experiences of the at-risk individual, to set aside prior assumptions, judgments, or interpretations, and to identify ways of bridging gaps in communication associated with negative emotions. The vital importance of empathy is stressed, drawing attention to the insights offered by neuroimaging studies and the role of mirror neurons in social cognition. It is widely acknowledged that when a clinician meets a person who wants to die by suicide, the clinician does not fully understand what is going on inside the mind of that individual. This book recognizes that any approach to suicide prevention must promote understanding of suicidal thoughts and feelings. The awareness that it fosters and the innovative perspectives that it presents will appeal to a wide readership.

In this book international experts address a range of key current issues relating to suicide. The opening chapters discuss nosology, definitions, clinical determinants, and conceptual models of the suicide process and consider the evidence regarding potential biomarkers of suicide risk based on neuroscientific research. Adopting a neo-Durkheimian perspective, the role of various social factors in the genesis of suicidal behavior is then explored in depth. Practical user-friendly tools that facilitate risk assessment by clinicians are provided, and detailed consideration is given to efficient and innovative strategies for the prevention of suicide and the treatment of suicidal behavior, such as psychotherapy, psychopharmacological approaches, and effective organization of care, including surveillance and the use of online tools. The final part of the book focuses on the need for and development of a personalized approach within the field of suicide prevention.

Re-Visioning Psychiatry explores new theories and models from cultural psychiatry and psychology, philosophy, neuroscience and anthropology that clarify how mental health problems emerge in specific contexts and points toward future integration of these perspectives. Taken together, the contributions point to the need for fundamental shifts in psychiatric theory and practice: • Restoring phenomenology to its rightful place in research and practice • Advancing the social and cultural neuroscience of brain-person-environment systems over time and across social contexts • Understanding how self-awareness, interpersonal interactions, and larger social processes give rise to vicious circles that constitute mental health problems • Locating efforts to help and heal within the local and global social, economic, and political contexts that influence how we frame problems and imagine solutions. In advancing ecosystemic models of mental disorders, contributors challenge reductionistic models and culture-bound perspectives and highlight possibilities for a more transdisciplinary, integrated approach to research, mental health policy, and clinical practice.

Epigenetics in Psychiatry covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this potentially very important and useful area of psychiatry. The elucidation of basic principles of epigenetic biology points to the creation of more optimal and effective therapies for major classes of psychiatric disease. In this regard, epigenetic therapy, the use of drugs to correct epigenetic defects, may help in the pharmacotherapy of patients with these disorders. With time, such advances may eventually point to replacements for psychotropic drugs presently of symptomatic value and low efficacy. Moreover, there is evidence to suggest that other forms of treatment commonly used in the management of psychiatric disorders, like psychotherapy and electroconvulsive therapy, may also act by epigenetic mechanisms. - Chapters review fascinating new areas of research across neuronal stem cells, cognitive disorders, and transgenerational epigenetics through drug addiction - Relates broad advances in psychiatric epigenetics to a modern understanding of the genome, transcriptome, and protein - Catalyzes knowledge discovery in both basic epigenetic biology and clinical application as epigenetic targets for drug discovery