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This fully updated and revised second edition address specifically some of the significant advances made in our understanding of the pathophysiology of penile cancer including discussion of the suspected role of the human papilloma virus in penile carcinogenesis. Similarly, the molecular pathways implicated in precancerous and penile cancer will be discussed as these are the present targets of novel therapeutic approaches to this disease. The text details the recent national and international diagnostic and treatment guidelines that have been developed by both the National Comprehensive Cancer Network© and the European Urological Association establishing evidence based standards upon which the care of penile cancer should be based. The text also covers significant advances made in the diagnostic and therapeutic approach to both primary tumors and inguinal nodal metastases resulting from penile cancer such as penile sparing surgery and minimally invasive inguinal lymph node surgery. Thetext will similarly highlights the improvement in cancer specific outcome in the management of loco-regionally advanced (N2/3) penile cancer managed by upfront systemic chemotherapy followed by consolidative surgery in appropriately selected patients based on recent prospective phase II data. It also covers the role of radiotherapy in the management of penile cancer for both primary tumors and/or at sites of regional or distant metastases. Finally, some of the novel systemic approaches being devised in the management of advanced penile cancer along with some upcoming international trials soon to be opened which likely will re-define the present therapeutic approaches to penile cancer are discussed. The Second Edition of Penile Cancer: Diagnosis and Treatment will constitute a comprehensive review of the above mentioned subjects in addition to a few select topics of high clinical relevance, with the readership predominantly consisting of urologists, medical and surgical oncologists, and other healthcare professionals.

Since the publication of the first edition of Urethral Reconstructive Surgery, important refinements have been added to the urologic surgical armamentarium. Extensively revised and updated, Advanced Male Urethral and Genital Reconstructive Surgery, Second Edition guides urologists in a practical manner on how to evaluate and manage complex urethral and male genital reconstructive challenges. Chapters have been added on wound healing, synchronous urethral strictures, non-transecting anastomotic urethroplasty (including muscle and vessel sparing), overlapping buccal grafts, male urethral slings, genital skin grafting, Peyronie's surgery, priapism, pediatric strictures and prosthetics. Such chapters greatly strengthen the overall appeal of the book. The volume closes with a new comprehensive appendix of preferred instruments.With broad contributions by international authorities in reconstructive urologic surgery, Advanced Male Urethral and Genital Reconstructive Surgery, Second Edition is a valuable resource for all urologists, from residents to reconstructive surgeons.

​Penile Cancer: Diagnosis and Management provides a comprehensive overview of penile cancer for medical and surgical urologists oncologists, and other healthcare professionals. This book highlights many of the significant advances made in this field, which include a discussion of penile-sparing surgical and radiotherapeutic approaches to select primary penile tumors typically of lower stage and grade as well as advances in our understanding of the epidemiology, risk factors, and pathophysiology of penile cancer. The book also addresses many of the novel diagnostic and therapeutic surgical approaches to inguinal lymph nodes, including dynamic sentinel node biopsy and minimally invasive surgery. The authors also discuss many of the clinical pearls and surgical considerations that can optimize treatment outcomes while minimizing the morbidity and inherent risk of complications in patients undergoing an open inguinal lymph node dissection. Lastly, the volume presents a discussion of the paradigm shift in the management of bulky inguinal lymph node metastases from penile cancer consisting of neoadjuvant systemic chemotherapy followed by consolidative surgical resection, which can offer an improved likelihood of survival as shown in a recent phase 3 clinical trial. Penile Cancer: Diagnosis and Management will serve as a resource for clinicians and researchers seeking an overview on the current state of knowledge in penile cancer. The editor has gathered leading worldwide experts in this field who have written a very practical and useful textbook for clinicians in an attempt to optimize patient outcomes and promote the pivotal scientific advances made in recent years.

Urethral reconstructive surgery can often be complex, time consuming and demanding. Enlightening urologists in a practical manner, Urethral Reconstructive Surgery evaluates and manages complex urethral problems. Written by a panel of experts in the field, Urethral Reconstructive Surgery offers the anatomy of the urethra and the aspects of wound healing and applicable plastic surgical techniques. A practical and comprehensive review, Dr. Brandes and his contributors focus on the methods for evaluating the extent and degree of urethral stricture and the decision making process.