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This comprehensive and authoritative reference presents the state-of-the-art computational methods applied to the field of neurosurgery. The book brings together leading neuroscientists, neurosurgeons, mathematicians, computer scientists, engineers, ethicists and lawyers, to open the new frontier of computational neurosurgery to a broad audience interested in the translational field of the application of computational models, such as deep learning, to the study of the brain and the practical applications of neurosurgery. The focus is primarily clinical, and there is a solid foundation of research aspects. With forewords by Michael L.J. Apuzzo and Enrico Coiera, the book is organized into 2 sections: (1) tenets of computational modeling, artificial intelligence, computational analysis, and analysis software; (2) computational neurosurgery applications, including neurodiagnostics, neuro-oncology, vascular neurosurgery, all the neurosurgical disciplines, surgical approaches, intraoperative applications, and ethics and legal aspects.

The brain weighs just three and a half pounds, but it governs every aspect of our lives...'A fascinating and wide-ranging account of what neurosurgery is really about – the past, present and future.'Henry Marsh, author of Do No Harm Since its inception in the early twentieth century, brain surgery has maintained an air of mystery. As the saying ‘it's not exactly brain surgery'suggests, the specialty has become synonymous with a level of complexity and meticulousness rivalled only by, well, rocket science. Warm, rigorous and deeply insightful, neurosurgeon Theodore Schwartz reveals what it's really like to get inside someone's head – where every second can mean the difference between life or death. Drawing from Schwartz's experience in one of New York's busiest hospitals, Gray Matters explores the short but storied history of brain surgery. From the dark days of the lobotomy to the latest research into the long-term effects of contact sports on athletes'cerebral health, Schwartz unfolds the fascinating story of how we came to understand this extraordinary, three-pound organ, which not only keeps us alive, but makes us who we are.'Fascinating... Schwartz's way with words is as skilful as his wielding of microscissors.'Mail on Sunday

“If you are at all curious about the brain or the surgeons who operate on it, Gray Matters is a must read and Dr. Theodore Schwartz is the perfect guide, a master brain surgeon and superbly talented writer. I have not read a better biography of our shared profession, and in Schwartz's talented hands, the most enigmatic 3 1/2 pounds of tissue in the known universe comes to light in remarkable and revelatory ways.”—Dr. Sanjay Gupta, CNN Chief Medical Correspondent, and New York Times and #1 Wall Street Journal bestselling author of Keep Sharp: Build a Better Brain at Any AgeA popular biography of brain surgery, by one of its preeminent practitionersWe've all heard the phrase “it's not brain surgery.” But what exactly is brain surgery? It's a profession that is barely a hundred years old and profoundly connects two human beings, but few know how it works, or its history. How did early neurosurgeons come to understand the human brain—an extraordinarily complex organ that controls everything we do, and yet at only three pounds is so fragile? And how did this incredibly challenging and lifesaving specialty emerge? In this warm, rigorous, and deeply insightful book, Dr. Theodore H. Schwartz explores what it's like to hold the scalpel, wield the drill, extract a tumor, fix a bullet hole, and remove a blood clot—when every second can mean life or death. Drawing from the author's own cases, plus media, sports, and government archives, this seminal work delves into all the brain-related topics that have long-consumed public curiosity, like what really happened to JFK, President Biden's brain surgery, and the NFL's management of CTE. Dr. Schwartz also surveys the field's latest incredible advances and discusses the philosophical questions of the unity of the self and the existence of free will. A neurosurgeon as well as a professor of neurosurgery at Weill Cornell Medicine, one of the busiest and most highly ranked neurosurgery centers in the world, Dr. Schwartz tells this story like no one else could. Told through anecdote and clear explanation, this is the ultimate cultural and scientific history of a literally mind-blowing human endeavor, one that cuts to the core of who we are.

Unique neurointerventional surgery resource analyzes landmark literature to inform optimal patient managementThe field of neurointerventional surgery is rapidly expanding with an ever-accelerating pace of technological innovations. While industry plays a significant role in designing new technology and defining indications for its use, practitioners need to evaluate and determine the most efficacious treatments for their patients. Neurointerventional Surgery: An Evidence-Based Approach by renowned endovascular neurosurgeons Min Park, M. Yashar S. Kalani, and Michael F. Stiefel examines the most common disease states in neurointerventional surgery through a critical lens. The unique text leverages evidenced-based data to inform treatment decisions and improve patient outcomes.The text is organized by 5 sections and 32 chapters, including the latest state-of-the-art interventions. Each of the chapters provides critical analysis of the'landmark papers'that established the foundation and standards for modern neurointerventional practice. An example is the rapidly changing understanding of large vessel occlusions in ischemic stroke that now strongly supports mechanical thrombectomy as a viable and important part of the treatment armamentarium.Key HighlightsContributions from internationally recognized leaders in academic neurointerventional surgery provide insightful and analytic perspectivesEncompasses the full continuum of neurointerventional procedures in one resource, from hemorrhagic and ischemic stroke to neoplasms and spine conditionsThe reader-friendly structure and chapter formatting facilitates understanding of often complicated decision-makingThe evidenced-based, multifaceted approach to neurointerventional surgery presented in this textbook makes it vital reading for residents, fellows, and practitioners in neurosurgery, as well as fellows in interventional neuroradiology and interventional neurology.

This truly comprehensive title addresses all aspects of the evaluation and management of carotid artery disease. The extracranial carotid artery is an area of confluence for both medical and surgical specialists. Given its unique position and function in the body, disease states that involve the carotid artery require a unique approach to ensure the best outcomes for patients. Developed by a multidisciplinary team of thought leaders from across medical, surgical, and radiological disciplines, Carotid Artery Disease: Evaluation and Management provides a diverse resource where readers can find presentation, evaluation, and management recommendations for any process involving the extracranial carotid artery, be it related to atherosclerotic, traumatic, inflammatory, or even oncologic disease. Indeed this title is a unique offering in that one can find traditional, and even exclusively medical, conditions within the same binding as surgical or interventional ones. Typically,access to this type of information requires the purchase of multiple different texts, but this complete title distills the evaluation and management of carotid artery disease into a one-of-a-kind, practical, accessible reference. A much-needed and invaluable contribution to the clinical literature, Carotid Artery Disease: Evaluation and Management will be of great interest to anyone early in his or her career and needing an introduction to the field, as well as seasoned clinicians in need of state-of-the-art, refresher information.

The ultimate guide to navigating and treating brainstem pathologies from master neurosurgeon Robert SpetzlerThe brainstem is one of the last bastions of surgical prohibition because of its densely packed ascending and descending tracts and nuclei carrying information to and from the brain. Although 10% of all pediatric tumors and 5% of all vascular anomalies occur in the brainstem, neurosurgeons have traditionally resisted dissecting lesions in this area. Recent advances in imaging, microscopy, anesthesia, and operative techniques have expanded the treatment paradigm for this most eloquent region of the brain.Surgery of the Brainstem, by internationally renowned neurosurgeons Robert F. Spetzler, M. Yashar S. Kalani, and Michael T. Lawton, along with an impressive cadre of global experts, is a comprehensive guide to managing disorders of the brainstem, thalamic region, and basal ganglia. Organized in seven sections with 33 chapters, the text opens with four sections covering a variety of topics. Section I presents the history of brainstem surgery; Section II examines anatomy, development, and pathology; Section III reviews patient examination, imaging, and monitoring; and Section IV provides a succinct overview of surgical approaches. Sections V-VII cover a wide range of adult and pediatric tumors, ischemia, stroke, aneurysms, arteriovenous malformations, and cerebral cavernous malformations. More than 300 high-quality clinical images and medical illustrations enhance the text.Key HighlightsA full spectrum of treatment modalities and outcomes, including open surgery, endoscopic approaches, stereotactic radiosurgery, radiotherapy, endovascular techniques, and revascularizationAn anatomy chapter featuring stunning Rhoton-style anatomical dissections delineates critical landmarks in the brainstem, thalamus, pineal region, and cranial nervesDetailed discussion of patient positioning and exposure of various brainstem domainsPearls on overcoming psychological, pathological, and anatomical barriers and managing complicationsUnderstanding the basic anatomy, pathology, and clinical complexities of the brainstem and thalamic regions is essential for safe navigation and treatment. This remarkable book will provide neurosurgeons with additional insights on performing resections and achieving the best possible outcomes for patients with pathologic conditions in this delicate region.

Part of the Neurosurgery by Example series, this volume on cerebrovascular neurosurgery presents exemplary cases in which renowned authors guide readers through the assessment and planning, decision making, surgical procedure, after care, and complication management of common and uncommon disorders. The cases explore the spectrum of clinical diversity and complexity within cerebrovascular neurosurgery, including aneurysms, ischemic/occlusive disease, arteriovenous malformation, dural arteriovenous fistula, and more. Each chapter also contains'pivot points'that illuminate changes required to manage patients in alternate or atypical situations, and pearls for accurate diagnosis, successful treatment, and effective complication management. Containing a focused review of medical evidence and expected outcomes, Cerebrovascular Neurosurgery is appropriate for neurosurgeons who wish to learn more about a subspecialty, and those preparing for the American Board of Neurological Surgery oral examination.

Perfect for anyone considering or training in this challenging specialty, Principles of Neurological Surgery, 4th Edition, by Drs. Richard G. Ellenbogen, Laligam N. Sekhar, and Neil Kitchen, provides a clear, superbly illustrated introduction to all aspects of neurosurgery–from general principles to specific techniques. Thorough updates from leading authors ensure that you'll stay abreast of the latest advances in every area of neurosurgery, including pre- and post-operative patient care, neuroradiology, pediatric neurosurgery, neurovascular surgery, trauma surgery, spine surgery, oncology, pituitary adenomas, cranial base neurosurgery, image-guided neurosurgery, treatment of pain, epilepsy surgery, and much more. - Offers comprehensive coverage without being encyclopedic – just the right amount of information for those in training or who need an introduction to the field. - Provides a strong visual understanding of the essentials of neurosurgery with abundant high-quality illustrations, including imaging, pathology, clinical and operative photographs, surgical line drawings, diagrams, tables, and figures. - Presents information in an easy-to-understand, well-written manner, helping you quickly grasp the principles and problems of today's neurosurgery. - Features new and improved videos, more emphasis on anatomy and radiology, and new evidence and techniques, keeping you up to date with the latest advances in the field. - Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Now in two volumes–an updated atlas to help you and disorders of the brain…This thoroughly revised and expanded atlas is the ideal reference for residents, fellows, and clinicians to review surgical procedures before entering the operating room. The authors provide step-by-step descriptions of techniques, clearly delineating indications and contraindications, goals, operative preparation and anesthesia, and postoperative management. The main focus of this book is on teaching neurosurgical techniques at the most detailed level.Features of the second edition:A new chapter on proton therapyAn expanded section covering the latest radiosurgery techniquesNearly 3,000 high-quality images aid rapid comprehension of surgical proceduresOnline access to more than 100 surgical technique videosThis book should be read cover to cover by young practitioners several times during their residency, and it will keep more experienced neurosurgeons up-to-date on the latest surgical techniques in the field.

Neurointerventional Techniques: Tricks of the Trade is a practical reference that includes core procedures used in the growing neurointerventional subspecialty. The step-by-step, concise presentation of procedures along with original line drawings and high-quality images concisely distill a wealth of information, making it easy for both novice and expert neurointerventionists to review how procedures are performed. The book includes over 50 specific procedures as well as important chapters on access points, physiological testing, and pharmacology in the endovascular suite.Key Features:Written by leading experts in neurointerventional practice Strong emphasis on complication avoidance throughout the text Covers both basic and more complex neuroendovascular procedures Appendices are rich with information on catheters, presented in an easy-to-access tabular format, as well as important guidance on intraoperative neurophysiologic monitoring as it applies to neurointerventional proceduresNeurosurgeons and neurointerventionists at all levels, from residents learning procedures to experienced practitioners needing a quick refresher, will find this book to be an invaluable resource that they will consult frequently in clinical practice.

The complex, highly technological field of neurovascular surgery is quickly expanding, encompassing traditional surgical approaches, as well as endovascular and neurointerventional techniques. The last decade has seen increased cross-specialty interest in utilizing minimally invasive techniques to help prevent and treat cerebrovascular disease. Concurrently, there has been important research analyzing the efficacy of surgical methods versus endovascular approaches – and the clip versus coil discussion is covered herein.Written by 21st Century pioneers in the field, this second, cutting-edge edition offers the latest science throughout 1,400 pages – and a remarkable video library – covering anatomy, diagnosis, epidemiology, history, treatment indications, technical nuances, outcomes, and complications. Internationally renowned experts from across the globe share clinical pearls and best practices, from the research lab to the ER to the OR. Medical, surgical, endovascular, cerebral revascularization, bypass surgery, radiation therapy, and other procedures are covered in depth. Evidence-based and transdisciplinary, the second edition covers the full spectrum of neurovascular pathologies, preoperatively and postoperatively, including:Ischemic Stroke and Vascular InsufficiencyCerebral and Spinal AneurysmsCerebral and Spinal Arteriovenous Fistulae and MalformationsVascular TumorsCarotid Artery DiseaseMoya-Moya DiseaseRevascularization techniquesOrganized into 11 primary sections, 99 richly illustrated chapters, and more than 140 videos, this volume is an invaluable, one-stop reference tool. It is a must-have for general, vascular and endovascular neurosurgeons; interventional radiologists; neurologists; critical care practitioners; and neuro-rehabilitation specialists.

A comprehensive review of surgical approaches and techniques for the posterior fossaThe ability to operate successfully in the posterior fossa requires a thorough understanding of its neuroanatomy and physiology, accurate localization of lesions, and optimal surgical technique. Principles of Posterior Fossa Surgery provides an in-depth review of this complex surgical region, with detailed coverage of anatomy, pathology, imaging, disease-based management, and surgical approaches. Written by a team of highly respected specialists, it will be a valued reference and refresher for clinicians who perform posterior fossa surgery, as well as for trainees. Special Features:Begins with a useful framework in neuroimaging, neuropathology, and microsurgical anatomy of the posterior cranial fossa Covers a wide range of approaches and pathologies in the region, including congenital Chiari malformations, infections, trauma, aneurysms, and tumors Highlights the anatomy of common surgical approaches, with numerous radiographic and endoscopic images that aid in visualizing concepts Provides full coverage of surgical techniques, starting with basic concepts and progressing to operations on more challenging entities like petroclival meningiomas, jugular bulb tumors, acoustic neuromas, complex basilar aneurysms, and posterior circulation aneurysms Includes comprehensive sections on surgical management of pediatric posterior fossa tumors and shunt surgery for lesions Shares the insights of prominent neurosurgeons from top centers around the world, who discuss their preferred strategies for tackling this challenging area of the brainFocusing solely on the posterior fossa, this book fills an important gap for neurosurgeons, skull base specialists, and residents and fellows who are training in this anatomically challenging region. It will enrich their understanding and knowledge of the field, expand their surgical armamentarium, and help achieve the most successful clinical outcomes.

Principles of Neurosurgery, by Drs. Richard G. Ellenbogen, Saleem I. Abdulrauf and Laligam N Sekhar, provides a broad overview of neurosurgery ideal for anyone considering or training in this specialty. From general principles to specific techniques, it equips you with the perspectives and skills you need to succeed. Comprehensive without being encyclopedic, this new edition familiarizes you with the latest advances in the field-neuroimaging, the medical and surgical treatment of epilepsy, minimally invasive techniques, and new techniques in position and incisions-and shows you how to perform key procedures via an online library of surgical videos at www.expertconsult.com. No other source does such an effective job of preparing you for this challenging field!Get comprehensive coverage of neurosurgery, including pre- and post- operative patient care, neuroradiology, pediatric neurosurgery, neurovascular surgery, trauma surgery, spine surgery, oncology, pituitary adenomas, cranial base neurosurgery, image-guided neurosurgery, treatment of pain, epilepsy surgery, and much more. Gain a clear visual understanding from over 1,200 outstanding illustrations-half in full color-including many superb clinical and operative photographs, surgical line drawings, and at-a-glance tables. Apply best practices in neuroimaging techniques, minimally invasive surgery, epilepsy surgery, and pediatric neurosurgery. Master key procedures by watching experts perform them in a video library online at www.expertconsult.com, where you can also access the fully searchable text, an image gallery, and links to PubMed. Keep up with recent advances in neurosurgery with fully revised content covering neuroimaging, the medical and surgical treatment of epilepsy, minimally invasive techniques, new techniques in position and incisions, deep brain stimulation, cerebral revascularization, and treatment strategies for traumatic brain injury in soldiers. Apply the latest guidance from new chapters on Cerebral Revascularization, Principles of Modern Neuroimaging, Principles of Operative Positioning, Pediatric Stroke and Moya-Moya, Anomalies of Craniovertebral Junction, and Degenerative Spine Disease. Tap into truly global perspectives with an international team of contributors led by Drs. Richard G. Ellenbogen and Saleem I. Abdulrauf. Find information quickly and easily thanks to a full-color layout and numerous detailed illustrations.