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This book documents the state of the art in pediatric neurosurgery with the intention of providing a comprehensive guide to the management of the full range of pediatric neurosurgical disorders that will aid in the delivery of optimal care. Detailed practical instruction, taking into account recent advances, is provided on the neurosurgical treatment of congenital brain malformations, cerebrovascular diseases, head injuries and spinal trauma, infections, functional disorders, congenital and developmental spinal disorders, and brain and spinal tumors. Pearls and pitfalls are highlighted, and attention drawn to the most useful tips and tricks. Information is also included on relevant related topics, including the principles of neuroimaging, the physiological responses of newborns, infants, and children to neurosurgical trauma, preoperative evaluation, anesthesiology and intensive care, and other forms of therapy. The authors are renowned experts in the field, and the text is supportedby a wealth of high-quality images. Handbook of Pediatric Neurosurgery will be of value for neurosurgeons of all levels of experience, as well as for pediatricians, neuroradiologists, neuropathologists, and neuro-oncologists.

This book presents a complete up-to date description of cavernoma disease together with its known biology, genetics and variable clinical presentation. It facilitates improved decision-making on surgical intervention by presenting different cases, highlighting the particular features of lesions such as anatomical location, eloquences of adjacent brain and type of presentation that are important when making decisions. In addition, the reader is brought up to speed with developments in the neuroimaging and active treatment techniques, especially surgical resection and radiosurgery. Finally, the natural history of the disease is taken into account and compared to the possible benefits of surgical treatment. Cavernomas of the CNS: Basic Science to Clinical Practice provides a comprehensive overview from the fundamentals of this condition, to special patient groups such as children and pregnant women. Therefore, it is an indispensable resource for neurovascular surgeons, neurosurgical residents and neurologists.

Outstanding endoscopic skull base surgical resource presents cutting-edge approaches from multidisciplinary global expertsTransnasal endoscopic skull base and brain surgery have undergone major technical advances in recent years. The accumulation of experience and exciting technological innovations – including high-definition cameras, more ergonomic and precise surgical instruments, as well as new hemostatic agents – have enabled safer and more efficacious treatment of lesions affecting highly complex and delicate regions. This fully revised and updated second edition of Transnasal Endoscopic Skull Base and Brain Surgery: Surgical Anatomy and its Applications builds on the acclaimed first edition, focusing on the correlation between endoscopic skull base anatomy and state-of-the-art clinical applications. Among these are the transplanum/transtuberculum, transcribrifom, transclival, and craniocervical junction surgical approaches.Renowned skull base surgeon Aldo Stamm and leading worldwide experts have compiled a comprehensive multidisciplinary textbook with 72 chapters in 14 sections, didactically organized by regions and diseases. Detailed descriptions of sinonasal, orbital, cranial base, and intracranial anatomy, imaging modalities, and in-depth surgical navigation techniques form the foundation of this remarkable book. The content reflects significant knowledge and diverse perspectives from masters in neurosurgery, otorhinolaryngology, head and neck surgery, neuroendocrinology, intensive care, neuro-anesthesiology, and other disciplines.Key HighlightsChapter summaries and highlights facilitate understanding and retention of complex conceptsMore than 700 beautiful anatomical, operative, and dissection illustrations and photographs enhance understanding of impacted areas20 accompanying videos provide guidance on endoscopic transnasal approaches in patients with diverse skull base diseasesPearls, pitfalls, and nuances throughout this book provide invaluable insights on achieving optimal outcomesNeurosurgeons, otolaryngologists–head and neck surgeons, and others will greatly benefit from the step-by-step endoscopic procedural guidance and tips in this quintessential skull base surgical reference.

The definitive state-of-the-art resource on pediatric endoscopic endonasal approachesToday, expanded endonasal approaches (EEA) have revolutionized the surgical treatment paradigm for pediatric central skull base lesions. Specially adapted micro-instruments have been developed to permit passage through the narrow sinonasal pathways in children, enabling access to the entire midline skull base, from the crista galli to the cervico-medullary junction.Pediatric Endoscopic Endonasal Skull Base Surgery by Harminder Singh, Jeffrey Greenfield, Vijay Anand, and Theodore Schwartz is the first textbook focused solely on endoscopic endonasal management of cranial base pathologies in children. The book reflects in-depth expertise from an extraordinary group of international contributors from five continents, who share extensive knowledge on this emerging field. Thirty chapters are presented in three comprehensive sections.Key FeaturesCore topics including anatomy, rhinological and anesthetic considerations, patient positioning and OR set-up, instrumentation, and endonasal corridors and approachesFifteen chapters detail endoscopic treatment of a full spectrum of pediatric pathologies, such as craniopharyngioma, meningoencephalocele, basilar invagination, and benign and malignant tumors, among othersDiscussion of multiple skull-base closure techniques, managing complications, and neurosurgical and otolaryngological postoperative careVisually rich, the succinct text is enhanced with more than 200 high-quality surgical illustrations and intraoperative photographs, as well as procedural videosThis unique reference is essential reading for neurosurgical and otolaryngology residents and fellows, as well as veteran surgeons, nurse-practitioners, and physician-assistants who treat and care for pediatric patients with skull-base conditions.

The first two sections of this text address endoscopic and keyhole surgical procedures for cranial base and deep brain structures. These sections provide a comprehensive, state-of-the art review of this minimally invasive field and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in cranial base surgery. The philosophy, techniques, indications and limitations of endoscopic and keyhole cranial base surgery are covered in detail. This reference includes a discussion of the basic principles of these approaches as well as the preoperative planning, intraoperative pearls, and reconstruction techniques. The thorough descriptions of the practical and technical aspects are accompanied by extensive illustrations, figures and operative images. Extending beyond the technical details of these procedures, this text provides a third section that focuses on a thorough analysis and comparison of theendoscopic, keyhole and traditional open approaches to specific intracranial regions. Utilizing a “target-based” approach, the utility of each surgical technique is evaluated in regard to accessing pathology of the anterior, middle and posterior fossa cranial base as well as the deep central regions of the brain. All chapters are written by experts in their fields and include the most up to date scientific and clinical information. Endoscopic and Keyhole Cranial Base Surgery will be a valuable resource to specialists in optimizing surgical results and improving patient outcomes.

A unique perspective on neuroendoscopic versus microsurgical techniques from world-renowned neurosurgeonsIn the last two decades, neuroendoscopy has evolved from a fringe neurosurgical tool to an established subspecialty focusing on the treatment of diverse cranial and spinal diseases. Today, neuroendoscopic technology is widely used to treat supratentorial diseases, skull base pathologies, craniocervical diseases, and spinal pathologies. Despite the expanded use of neuroendoscopy across several subspecialties, its benefits and disadvantages versus those of traditional microsurgical methods remain highly controversial. Contradictory evidence in the neurosurgical literature adds to the surgical decision-making challenges for veteran and novice practitioners alike.Controversies in Neuroendoscopy by Peter Nakaji and Hasan Zaidi fills an unmet need for a book encompassing best practices, patient selection, and limitations and advantages of neuroendoscopic surgical approaches. Each case presents firsthand knowledge of internationally esteemed neurosurgeons, with a moderator, an endoscopic expert, and an expert in traditional microsurgical approaches. The unique discussion of neuroendoscopy versus microsurgery enables readers to compare the benefits and pitfalls of endoscopic and open microsurgical procedures for a wide range of conditions.In-depth comparative guidance on applications of the flexible endoscope, rigid endoscope, 3D endoscope, and high-definition 2D endoscope versus the microscopeA full spectrum of neurological conditions across the age continuum with comparative approaches for skull base surgery, pituitary surgery, hydrocephalus, spinal surgery, peripheral nerve surgery, and arachnoid cyst fenestrationRadiological imaging and intraoperative photographs enhance cases and provide precise, insightful technical guidanceHigh-quality color illustrations from the skilled medical illustrators at Barrow Neurological Institute reinforce key points and surgical techniquesNeurosurgery residents, neurosurgeons, and spine surgeons will all benefit from reading this remarkable book cover to cover, and they will no doubt use it as a go-to resource for specific cases.

The definitive textbook on state-of-the-art fluorescence-guided neurosurgeryAdvances in fluorescence-guided surgery (FGS) have resulted in a paradigm shift in neurosurgical approaches to neuro-oncological and cerebrovascular pathologies. Edited by two of the foremost authorities on the topic, Fluorescence-Guided Neurosurgery: Neuro-oncology and Cerebrovascular Applications encompasses the depth and breadth of this groundbreaking, still nascent technology. The book reflects significant contributions made by world renowned neurosurgeons Constantinos Hadjipanayis, Walter Stummer, and esteemed contributors on the growing uses of 5-aminolevulinic acid (5-ALA) and other FGS agents.The European Medicine Agency approved 5-ALA in 2007, heralding the birth of FGS globally. In 2017, the U.S. Food and Drug Administration approved 5-ALA (Gleolan) as an imaging agent to facilitate realtime detection and visualization of malignant tissue during glioma surgery. In the two decades since Dr. Stummer's initial description of 5-ALA FGS in a human patient, major strides have been made in its practical applications, leading to improved resection outcomes. As FGS is increasingly incorporated into neurosurgical practice, it holds promise for future innovations. Generously-illustrated and enhanced with online videos, this textbook is the definitive resource on the subject.Key FeaturesThe improved efficacy of 5-ALA for resecting high- and low-grade gliomas, recurrences, meningiomas, brain metastases, spinal cord tumors, pediatric brain tumors, and other adult tumorsThe future of fluorescence, including potentially powerful new fluorophores molecularly targeted specifically to tumorsThe use of the fluorescent agent indocyanine green (ICG) for brain tumors, cerebral aneurysms, AVMs, and cerebral vascularizationSpecial topics such as fluorescein, illuminating tumor paint, confocal microscopy, Raman spectroscopy, and integrating FGS with intraoperative imaging and brain mappingThis single accessible reference presents the current state-of-the-art on this emerging, exciting surgical technology. As such, it is a must-have for neurosurgical residents, fellows, and practicing neurosurgeons.

Part of the Neurosurgery by Example series, this volume on surgical neuro-oncology presents exemplary cases in which renowned authors guide readers through the assessment and planning, decision making, surgical procedure, after care, and complication management of common and uncommon disorders. The cases explore a number of different types of nervous systems tumors, including glioblastoma, medulloblastoma, skull tumors, and more. Each chapter also contains'pivot points'that illuminate changes required to manage patients in alternate or atypical situations, and pearls for accurate diagnosis, successful treatment, and effective complication management. Containing a focused review of medical evidence and expected outcomes, Surgical Neuro-Oncology is appropriate for neurosurgeons who wish to learn more about this subspecialty, and those preparing for the American Board of Neurological Surgery oral examination.

This book presents, in a stepwise and interactive fashion, approximately 75 cases that reflect the wide spectrum of pathology encountered in this region. Each case description commences with a concise clinical scenario. High-quality radiologic, laboratory, and histopathologic images depicting the differentiating features of the lesion subtype in question are then presented, and key operative and clinical management pearls are briefly reviewed. The interdisciplinary nature of this easy-to-use color atlas and textbook reflects the fact that the management of patients with sellar and parasellar lesions is itself often interdisciplinary. The format is unique in that no similar interdisciplinary book is available on lesions of this region of the brain. Atlas of Sellar and Parasellar Lesions: Clinical, Imaging, and Pathologic Correlations is of great value for practitioners and trainees in a range of medical specialties, including radiology, neurology, endocriniology, pathology, oncology, radiation oncology, and neurosurgery.

The essential guide to managing tumors of the central nervous systemNeuro-Oncology: The Essentials, Third Edition, is a comprehensive introduction to the fundamental science and core clinical concepts behind the successful multidisciplinary management of patients with brain and spine tumors. Among the updates to this new edition are eight new chapter topics, including: Endoscopic Approaches, Pediatric Supratentorial Tumors, and Neuro-Oncology in the Developing World. The book begins with basic science, progresses to clinical applications, and includes a robust section on specific tumor types.Key Features:A major revision, with a 20% increase in content and over 35% increase in figuresEditor's Notes at the end of each chapter briefly summarize a topic, provide a historical perspective on a topic, add a current reference, or highlight salient pointsDemonstrates the latest surgical navigation techniques, including stereotaxy and intraoperative MRI, used to access hard-to-reach tumors This new edition is an invaluable reference for all neurosurgeons, neurologists, and oncologists, as well as residents and fellows, and it will be a treasured volume in their medical libraries for years to come.

Because the base of the skull has proven to be one of the most challenging regions of the body to access, treatment options were once limited for patients with tumors or lesions in this area. However, with recent advancements and breakthroughs in treatment, patients with skull base tumors now have an array of surgical options that can help them return to leading a normal and active life. The Endoscopic Endonasal Approach (EEA) is an innovative surgical technique used to remove brain tumors and lesions—some as large as softballs—all through the nose.

Now in two volumes–an updated atlas to help you and disorders of the brain…This thoroughly revised and expanded atlas is the ideal reference for residents, fellows, and clinicians to review surgical procedures before entering the operating room. The authors provide step-by-step descriptions of techniques, clearly delineating indications and contraindications, goals, operative preparation and anesthesia, and postoperative management. The main focus of this book is on teaching neurosurgical techniques at the most detailed level.Features of the second edition:A new chapter on proton therapyAn expanded section covering the latest radiosurgery techniquesNearly 3,000 high-quality images aid rapid comprehension of surgical proceduresOnline access to more than 100 surgical technique videosThis book should be read cover to cover by young practitioners several times during their residency, and it will keep more experienced neurosurgeons up-to-date on the latest surgical techniques in the field.

Principles and Practice of Stereotactic Radiosurgery, Second Edition serves as the definitive reference textbook for SRS practitioners. It provides a theoretical basis for the use of therapeutic radiation including imaging techniques and radiobiology. The bulk of the textbook contains chapters that are comprehensive in scope on all diseases that are treated by SRS. Lastly, it addresses administrative and technical aspects of running an SRS unit. Each chapter provides an expansive treatment of the subject, with emphasis placed on the technical aspects of SRS so that practitioners in this field can use it as a daily reference.Written by noted experts in the field, Principles and Practice of Stereotactic Radiosurgery, Second Edition is the only reference needed for neurosurgeons, radiation oncologists and medical physicists at all levels of training and practice who are interested in SRS.