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In spite of great improvements in prehospital, critical care, and surgical management, traumatic brain injury is still a leading cause of death and disability resulting in great socioeconomic burden. This book provides a comprehensive and practical perspective of the management of traumatic brain injury, from prehospital setting to discharge. Even more, the book highlights the importance of pathways (Trauma Center and Neurocritical Care Unit) and the central role of the specialized neurocritical care team and neurological critical care units in the practice of neurocritical care. Encouraging a practical, protocol-driven, multidisciplinary approach for both adult and pediatric patients, the authors provide a methodological description of the diagnostic and therapeutic management of patients with traumatic brain injury throughout the patient journey. Neuromonitoring assumes predominant importance, with an increasing role of noninvasive monitoring (near-infrared spectroscopy, Pupillometry, transcranial color Doppler-TCD, transcranial color duplex-TCCD, and optic nerve ultrasound) and neurophysiology (electroencephalography and evoked potentials) for early recognition of complications and rapid assessment of the effectiveness of medical treatment. However, the increasing amount of data increases the complexity of interpreting the collected information. The basic principles of multimodal monitoring and the computer-assisted method are presented to provide an overview of the future direction regarding the integration and interpretation of different data obtained from various techniques.Paying particular attention to prognosis and treatment-limiting decisions, the authors reviewed the critical role of neurorehabilitation and the clinical and bioethical perspective on brain death, organ donation, and communication with the family.

This second updated volume on breast cancer provides a comprehensive overview of its clinical management and current therapies. Updated to reflect the changes in breast cancer staging, the progress in immunotherapy approaches, as well as the latest guidelines for therapies, this book brings readers up to speed with the latest therapeutic regimens in breast cancer and provides an in-depth account of current and new therapeutic approaches. The most important phase III trials, high quality meta-analysis, consensus reports and guidelines are extensively discussed in this new edition and provide the reader with the most up-to-date information.Divided in themed parts, the book examines invasive breast cancer, pre-operative systemic therapy surgical management and recurrence among others, thus providing an in-depth account of breast cancer at the clinical stage. Among the themed parts are a section dedicated to special therapeutic problems, such as breast cancer in older women, Paget'sdisease and phyllodes tumors and a section on supportive and follow-up care. By adopting a multidisciplinary approach to breast cancer, this book is a must-have for breast cancer practitioners. With a high number of colored illustrations and edited by highly experienced clinicians, this work enables readers to gain an interdisciplinary perspective on breast diseases. Contributions from an international team of experts present invaluable insight into clinical practice across different settings. Covering both theoretical and practical aspects of breast cancer, this is a highly informative and carefully presented book which will appeal to an international audience of medical, radiation and surgical oncologists.

This book offers the reader sound advice on how to perform optimal conventional pediatric radiographs and how to obtain quick and easy organ dose estimates in order to improve the optimization process in pediatric imaging. Clear guidelines are provided for minimization of the radiation exposure of children through optimization of the radiation exposure conditions, and conversion coefficients are presented for calculation of the organ doses achieved in organs and tissues during conventional pediatric radiography, taking into consideration both optimal and suboptimal radiation field settings. Previously published conversion coefficients have failed to represent the variation in radiation field settings in daily clinical routine, which has made it difficult for the pediatric radiologist to estimate the impact of the field settings on absorbed doses in organs and tissues. The aim of this book, co-written by a pediatric radiologist, a physician and physicist, and a medical radiation technologist, is to address this issue by providing, for the first time, a thorough overview of clinical radiation field settings and their implications for radiation protection. An accompanying volume is devoted to fluoroscopy.

This second volume of the handbook on breast disease provides a comprehensive overview of its clinical management and current therapies. It brings readers up to speed with the latest guidelines and therapeutic regimens in breast cancer and provides and in-depth account of current and new therapeutic approaches. Divided in themed parts, the book examines invasive breast cancer, pre-operative systemic therapy surgical management and recurrence among others, thus providing an in-depth account of breast cancer at the clinical stage. Among the themed parts are a section dedicated to special therapeutic problems, such as breast cancer in older women, Paget's disease and phyllodes tumors, and a section on supportive and follow-up care. By adopting a multidisciplinary approach to breast cancer, this book is a must- have for breast cancer practitioners. With a high number of colored illustrations and edited by highly experienced clinicians, this work enables readers to gain aninterdisciplinary perspective on breast diseases. Contributions from an international team of experts present invaluable insight into clinical practice across different settings. Covering both theoretical and practical aspects of breast cancer, this is a highly informative and carefully presented book which will appeal to an international audience of medical, radiation and surgical oncologists.

1897 wurde unter dem ersten Ordinarius für Kinderheilkunde der Medizinischen Fakultät Graz, Prof. Theodor Escherich, die erste Röntgeneinrichtung in einem Kinderkrankenhaus in Europa installiert. Bis in die 50er Jahre gehörte das Erlernen der gebräuchlichen Röntgenuntersuchungen zur Ausbildung eines Kinderarztes. 1963 wurde die European Society of Pediatric Radiology in Paris gegründet und auf dem Kinderärztekongress in Köln die Arbeitsgemeinschaft Pädiatrische Radiologie, aus der die Gesellschaft für Pädiatrische Radiologie der Kinderradiologen des gesamten deutschen Sprachraumes hervorging. Die Entwicklung von Sonographie und MRT beeinflusste die Kinderradiologie grundlegend. Ihr konsequenter Einsatz senkt die medizinisch verursachte Strahlenexposition bei Kindern und Jugendlichen weitestgehend.Dieses Buch gibt einen detaillierten Überblick über die Entwicklung und damit auch über die Bedeutung der Kinderradiologie in Deutschland, den Niederlanden, Österreich und der Schweiz.

Direct from the Cleveland Clinic Foundation, Endovascular Techniques in the Management of Cerebrovascular Disease is intended for neurologists, neurosurgery fellows-in training, and practicing clinicians with an interest in endovascular procedures. This essential volume:Reviews equipment, devices, and therapeutic agents such as anti-coagulants and