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Completely revised and updated, the second edition of this authoritative guide provides the latest information on the diagnosis, treatment, and ongoing management of pulmonary issues in children. The book covers genetic, congenital, and allergic conditions, as well as acquired and infectious respiratory ailments. Pulmonary issues related to other systemic disorders are also covered, along with respiratory care and pediatric sleep medicine. More than 300 finely detailed images complement the text. New Second Edition Features Expanded content on sleep medicine, including sleep development and maturation, insomnia, parasomnias, sleep-related movement disorders, and obstructive sleep apnea Expanded coverage of functional respiratory disorders Cystic fibrosis newborn screening and CFTR-related metabolic syndrome Expanded coverage of pneumonia, including when caused by COVID-19 Expanded coverage of primary ciliary dyskinesia Vaping and other forms of nicotine exposure Content HighlightsFoundation—anatomy; physiology; physical examination; pulmonary testing; imaging; and bronchoscopy Allergic Conditions—bronchopulmonary aspergillosis; hypersensitivity pneumonitis; eosinophilic pneumonia; and asthma Anatomical Disorders—congenital abnormalities of the upper airway; congenital lung anomalies; and chest wall and spinal deformities Upper Airway Infections—croup, epiglottitis, and bacterial tracheitis Lower Airway Infections—bronchiectasis; bronchiolitis; viral pneumonia (including when caused by COVID-19); nonviral pneumonia; complications of pneumonia; recurrent pneumonia; tuberculosis; and nontuberculous mycobacteria Noninfectious Pulmonary Disorders—atelectasis; respiratory disorders associated with systemic inflammatory diseases; interstitial lung disease; bronchopulmonary dysplasia; pleural effusion (noninfectious); pneumothorax and pneumomediastinum; and pulmonary hemorrhage Pediatric Sleep Medicine—sleep development and maturation; obstructive sleep apnea; home sleep testing; sleep-related movement disorders; insomnia; parasomnias; narcolepsy and other disorders of excessive somnolence; sudden infant death syndrome and brief resolved unexplained events; and congenital central hypoventilation syndrome Other Pulmonary Issues—acute aspiration and aspiration-related lung disease; lung transplant; asthma and other respiratory disorders associated with obesity; and functional respiratory disorders Genetic Disorders—cystic fibrosis; cystic fibrosis newborn screening and CFTR-related metabolic syndrome; and primary ciliary dyskinesia and other genetic lung diseases Lung Disease Associated With Systemic Disorders—respiratory considerations in children with cardiac disease; lung disease associated with endocrine disorders; pulmonary complications of gastrointestinal diseases; pulmonary complications of sickle cell disease; pulmonary manifestations of oncological disease and treatment; pulmonary complications of immunologic disorders; and pulmonary complications of neuromuscular disorders Treating and Managing Pulmonary Disease—airway clearance techniques; aerosol delivery of medication; bronchodilators; antibiotics for pulmonary conditions; nutritional aspects of pulmonary conditions; oxygen therapy; and nicotine and tobacco

COPD remains a major cause of ill health, disability, healthcare costs and premature mortality. Scientists and clinicians across many countries have made great efforts to understand this important disease, and these have yielded positive results. This Monograph provides an up-to-date overview of what is happening in this exciting field, both at a basic and a clinical level. Beginning, crucially, with the patient's perspective, the chapters that follow consider the best way to define COPD, changes in the disease's incidence and prevalence, and offer new insights into the role of the microbiome in COPD, advances in imaging and treatment options, both pharmacological and non-pharmacological. Taken together, these chapters are an important contribution to the Monograph series and the COPD field in general.

This book provides a comprehensive and up-to-date overview of all the upper and lower airways disorders and broadens their understanding by combining ENT and pulmonology disciplines. The volume opens with a general overview on the airways, before describing symptoms, infections and allergies. In addition to the upper airway tumors, specific lower, and upper airway disorders, other topics addressed by the book are pediatric lower airway disorders, sleep related breathing disorders, trauma, reflux, and interventional pulmonology. The closing part discusses the airway protection and includes a chapter on gender and pulmonary diseases. Written by experts in the fields, the book is a valuable resource for both specialists and trainees in ENT, pulmonology, and pediatrics.

This book presents the best practice, indications and drugs most used in the practice of noninvasive ventilation (NIV). In the last two decades NIV has made a lot of progress in different scenarios and etiologies of respiratory failure. The treatment of these patients frequently involves the use of drugs to control patient's symptoms such as dyspnea, discomfort and some of them can have direct or indirect effects on lung function. The volume is organized into various sections - dedicated both to adults as well as pediatrics - where the most frequent clinical conditions requiring for the use of a pharmacological support are described. Furthermore, this book is conceived as a quick reference guide including an analysis of the indications of drugs dosage and the pharmacological interactions that can be observed in lung function in patients undergoing NIV. Thanks to its contents, readers can quickly consult indications, contraindications, doses, the most suitable treatments to achieve the maximum NIV as well as the most important side effects reported by clinicians. In this book specialists in critical care and pharmacology, managing both adult and pediatric population, shed a light to the proper medication management and best drugs choice in patients with indications for NIV

Respiratory care is undergoing a period of major change as it cautiously begins to embrace digital transformation. Catalysed by the need for remote consultation in the pandemic, time-honoured approaches to delivering care are now being challenged by technology-based initiatives. This Monograph deftly guides the reader through the potential benefits and pitfalls of such change, breaking the discussion down into three areas: technological opportunities and regulatory challenges ; social benefits, challenges and implications; exemplars of digital healthcare. Each chapter reviews contemporary literature and considers not ‘if'but ‘how'a digital respiratory future can provide optimal care. The result is an authoritative, balanced guide to developing digital respiratory health.

Cystic Fibrosis has seen dramatic advances in treatment since the last edition, including targeted cystic fibrosis transmembrane conductance regulator (CFTR) protein modulators for most CFTR gene abnormalities. This new fifth edition is an update and expansion of the rapid clinical and scientific advances in improving prognosis, and the impact of COVID-19, all of which has transformed conventional models of care. It covers basic science, such as how detailed understanding of the biology of the CFTR gene and protein has led to novel and beneficial therapies, as well as all aspects of clinical management in high-, middle- and low-income settings and the voices of individuals with CF from across the world. It will be a useful reference for clinicians, including all levels of trainees, across the whole multidisciplinary team, scientists and students.Key Features• Follows an appealing organization of chapters, by developing fundamental knowledge of the reader before moving on to more complex or developing topics.• Presents a comprehensive, authoritative and up-to-date text, integrating fundamental science and clinical aspects of cystic fibrosis providing an attractive read for clinicians, trainee doctors and scientists.• Draws on global expertise and reflects best evidence-based practice from experts conducting cutting-edge clinical and basic science research from around the world.

Asthma is a common chronic respiratory disease that causes substantial morbidity and has been challenging to treat due to its heterogeneous onset, environmental triggers, severity, and treatment response. To update the field on the rapid advances in this field, Precision Approaches to Heterogeneity in Asthma follows its highly successful predecessor, Heterogeneity in Asthma. In this new volume, noted authorities Allan R Brasier and Nizar N Jarjour and a cadre of leaders in the field incorporate new work advancing our understanding of phenotypes (endotypes) of disease, regional variations in ventilation, systems approach to analyzing the findings from studies of inducible phenotypes, and emerging results of biomarker-informed clinical trials. This work will facilitate our current understanding of the spectrum of disease etiology, prognosis, and the likelihood of responding to the range of available therapeutic interventions.

This book serves as a guide to the pulmonary and critical care complications of hematopoietic stem cell transplantation (HSCT). HSCT is an important therapeutic modality for a variety of malignant and non-malignant conditions. The outcomes of these patients have been improving and the number of HSCT cases is increasing around the world. These patients, however, continue to have post-transplant complications related to conditioning regimens and graft vs. host disease. Pulmonary complications following HSCT remain a major cause of morbidity and mortality in this patient population.The book begins with an overview of HSCT and graft vs. host disease. Chapters then cover particular complications, including immunological changes in lungs, diffuse alveolar hemorrhage, bronchiolitis obliterans and pulmonary fibrosis. Other complications, including neurologic, renal, gastrointestinal, and cardiac, are covered. Chapters are comprehensive and consistent with each defining the scope of the complication, epidemiology, risk factors, diagnostic approach, management, outcome and predictors of outcome, and future directions. The book provides insight as well on matters that arise during the care of HSCT patients such as provider burnout, nursing care, intensive care unit organization, nutritional support, and pulmonary and physical rehabilitation. This is an ideal guide for pulmonologists, critical care physicians, transplant specialists, oncologists, and relevant trainees caring for patients who have undergone HSCT.

The book offers a comprehensive overview of ENT diseases during pregnancy, postpartum and lactating period. It brings together the experience of authors from more than 25 countries and aims to provide a broader understanding of the diagnosis, prevention and treatment of the ENT pathologies in pregnant and lactating women. The book is organized in 7 main parts according to the ENT subspecialties, and each chapter features a reader-friendly, uniform structure. It includes developments about COVID-19 infection. ENT Diseases: Diagnosis and Treatment during Pregnancy and Lactation will appeal to a wide readership, from ENT practitioners through allergists and pulmonologists, to trainees and students in ENT, obstetrics/gynecology.​

Chronic obstructive pulmonary disease (often known as COPD) is a respiratory disease that affects more than 400 million people worldwide. In 2019, COPD was responsible for 3.23 million deaths globally. This makes COPD the third greatest cause of mortality worldwide. People with COPD frequently experience increasing levels of breathlessness as the disease advances. This can cause a significant financial burden due to the limitations on workplace and home productivity, and costs of medical treatment. Therefore, delivering comprehensive management for people living with COPD is important to lessen such a burden. This book intends to provide comprehensive expert review chapters on the most significant aspects in the management of COPD from diagnosis to treatment through clear insights and explanations. It offers thorough evaluations that provide clinicians involved in COPD management at all levels with a brief, all-encompassing reference to symptoms, diagnosis, and treatment. This book covers four major areas in COPD management, including disease physiology and pathophysiology, diagnosis tools, disease burden, and management of stable and non-stable COPD.

Asthma, Pneumonien, und chronischer Husten zählen zu den häufi gsten Krankheiten in der kinderärztlichen Praxis. Dieses Buch ist eine praxisorientierte und zugleich kompakte Einführung in die Kinderpneumologie. Erfahrene Kinderpneumologen vermitteln hier, was ihnen wichtig ist für eine gute Patientenbetreuung. Literaturhinweise dienen der weiteren Vertiefung auch zu Erkenntnissen, die noch keinen Einzug in die Routineversorgung gefunden haben.

The 19 sections of this second edition of the ERS Handbook of Paediatric Respiratory Medicine cover the whole spectrum of paediatric respiratory medicine, from anatomy and development to disease, rehabilitation and treatment. The editors have brought together leading clinicians to produce a thorough and easy-to-read reference tool. The Handbook is structured to accompany the paediatric HERMES syllabus, making it an essential resource for anyone interested in this field and an ideal educational training guide.

This book addresses an unmet need in the care of adolescents and young adults with lung disease. The increasing survival of young adults with childhood-onset pulmonary conditions is a testament to major advances in treatments and health care delivery. With the increase in survival of children with chronic respiratory conditions, there is a need for formalized transition programs to integrate adolescents and young adults into the adult model of care. This book helps fill gaps in knowledge to best achieve that initiative.This book takes a comprehensive approach to transition care in pulmonary medicine by satisfying the following objectives: 1) Understand the barriers and developmental challenges in the transition from pediatric to adult care for patients with chronic childhood-onset pulmonary disease; 2) Learn about successful evidence based transition models in pulmonary disease populations, focusing on key process and outcome measures for success; and 3) Develop knowledge to design, implement, and measure a transition program based on evidence and expert opinion. In the first section, the book outlines general principles of transition care that are applicable to all patients regardless of underlying disease process and describe best practices for performing necessary research in transition care. In the second section, the book explores psychosocial factors known to play a role in affecting transition outcomes, including parental support, psychological development, and socioeconomic factors. In the final section, transition outcomes and best practices in specific respiratory diseases are outlined. With a focus on populations with chronic pulmonary disease, this book highlights the challenges and barriers of transition, reviews model systems to understand the essential components of a transition program, and provides evidence-based information to navigate these barriers and achieve successful outcomes during transitionto adulthood.This is an ideal guide for pediatric and adult pulmonary providers caring for patients who are transition age, as well as multidisciplinary care team members who work with these providers in care models on transition projects to improve the transition process.

This book comprehensively addresses the use of pulmonary function measurement for the evaluation, screening and timing of noninvasive mechanical ventilation (NIMV) from hospital to home care. To do so, it describes three clinical stages of NIMV support: before NIV, to detect early markers and determine whether NIV is appropriate; during NIV, to evaluate NIV response; and in long-term NIV support. Additionally, it assesses a range of complementary health care organizations (pulmonary function labs, pneumology wards, semi-intensive care units and home mechanical ventilation programs), techniques (chest physiotherapy/airway secretions, etc.) and applications. In closing, the book offers practical recommendations on how noninvasive ventilation and lung function measurement can improve outcomes and quality of life, making it a valuable resource for all specialists, e.g. intensivists and pneumologists, as well as anesthesiologists and therapists.

This book provides an overview of the latest experimental work on sex-based differences in lung function and inflammation. Readers will learn how these differences relate to individual predispositions for the development of lung disease in men and women, and in different stages of their reproductive lives. Further, the book focuses on diseases that predominantly affect women or men, with an emphasis on the physiological mechanisms underlying their pathobiology. In turn, these findings are complemented by chapters on recent studies, which investigate how circulating sex hormone levels impact the lung's innate immune response to environmental agents and air pollution. The pathogeneses of asthma and viral respiratory infection are also major focus areas. As an outlook, the book also discusses current and future research directions aimed at developing sex-specific therapies for lung disease. To examine these anatomical and physiological differences in the male and female respiratory systems, the authors employ a broad range of methods from molecular and clinical biology. Accordingly, the book will be a fascinating read for physiologists and clinicians alike.

This book covers the up-to-date advancement of respiratory monitoring in ventilation support as well as detecting the physiological responses to therapeutic interventions to avoid complications. Mechanical ventilation nowadays remains the cornerstone in life saving in critically ill patients with and without respiratory failure. However, conclusive evidences show that mechanical ventilation can also cause lung damage, specifically, in terms of ventilator-induced lung injury.Respiratory monitoring encloses a series of physiological and pathophysiological measurements, from basic gas exchange and ventilator wave forms to more sophisticated diaphragm function and lung volume assessments. The progress of respiratory monitoring has always been accompanied by advances in technology. However, how to properly conduct the procedures and correctly interpret the data requires clear definition.The book introduces respiratory monitoring techniques and data analysis, including gas exchange, respiratory mechanics, thoracic imaging, lung volume measurement, and extra-vascular lung water measurement in the initial part. How to interpret the acquired and derived parameters and to illustrate their clinical applications is presented thoroughly. In the following part, the applications of respiratory monitoring in specific diseases and conditions is introduced, including acute respiratory distress syndrome, obstructive pulmonary diseases, patient-ventilator asynchrony, non-invasive ventilation, brain injury with increased intracranial pressure, ventilator-induced diaphragm dysfunction, and weaning from mechanical ventilation.This book is intended primarily for ICU physicians and other practitioners including respiratory therapists, ICU nurses and trainees who come into contact with patients under mechanical ventilation. This book also provides guidance for clinical researchers who take part in respiratory and mechanical ventilation researches.

•Compilation of interesting cases in Pulmonary Medicine in day-to-day clinical practice which are challenging and educative. •Each case follows a step-by-step approach including history, salient findings on physical examination, and relevant investigations for diagnosis. •Each case has lot a of radiological images, which makes reading extremely interesting. •Plethora of cases including interesting tuberculosis, multidrug resistant (MDR), and extensively drug-resistant (XDR) cases. Diffuse parenchymal lung diseases, thoracic malignancies, and allergic bronchopulmonary aspergillosis. •Rare cases such as pulmonary sequestration, alveolar microlithiasis, endobronchial polyp, carcinoid syndrome, Chilaiditi syndrome, and lymphotracheal fistula.

Cystic fibrosis is a disease that affects the entire body. It tends to be thought of as primarily a pulmonary disease since pulmonary decline is the main factor in early mortality. Because of the multi-system nature of the disease, a better understanding of cystic fibrosis expands the family physician's understanding of subjects ranging from genetics to pulmonary function to nutrition to colon transport to hydration to electrolyte management. The primary care philosophy is unique in that it always considers how a narrow problem can affect an individual globally. Cystic Fibrosis care can often feel fractured to patients as they are sent to multiple specialists to deal with problems outside of the comfort level of a prior or current specialist. With a broad medical philosophy, care is more inclusive as clinicians can manage topics such as diabetes and preventive care without multiple referrals and additional appointments. Family physicians are well-positioned and well-qualified to competently meet many of the care needs of those with cystic fibrosis. This book is edited by a family medicine physician who has specialist level experience with the disease. It opens with a background on cystic fibrosis foundations and centers to familiarize the reader. The next chapter gives a basic overview of the disease. Each of the subsequent chapters provide a comprehensive look at how cystic fibrosis affects other areas of the body that the primary care physician should be familiar with. Major components of cystic fibrosis such as physiology, spirometry, inflammation, airway clearance, chronic infection, cystic fibrosis related diabetes and pancreatic insufficiency, among others, are thoroughly explained. Written by experts in the field, Cystic Fibrosis in Primary Care appeals to all family physicians as well as specialists, residents, medical students physician assistants and nurse practitioners alike.

Collaboratively authored by international experts and innovators, this book serves as a comprehensive introduction to flexible bronchoscopy in children, a guide to normal and abnormal bronchoscopy findings, and as the first pediatric bronchoscopy text to describe the array of innovative technologies now being utilized in advanced diagnostic and interventional bronchoscopy programs. Flexible bronchoscopy is a core clinical service provided by academic pediatric pulmonary medicine programs and a critical skill that trainees are expected to develop. The role of flexible bronchoscopy in the care of children with disorders of the respiratory tract has evolved rapidly over the past decade due to technological advances in diagnostic and therapeutic instruments. While many of these tools were designed for adult patients, pediatric pulmonologists have adapted them to meet the unique needs of children. The book is organized into three sections: thehistory and fundamentals of flexible bronchoscopy; the role of flexible bronchoscopy in evaluation of pediatric respiratory tract disorders; and advanced diagnostic and interventional bronchoscopy. Throughout, images and videos enhance the text and provide invaluable perspective. This is an ideal guide for practicing pediatric pulmonologists and trainees, and will also prove useful to pediatric anesthesiologists, intensivists, otolaryngologists and respiratory therapists.

This is a comprehensive and authoritative textbook on pediatric pulmonology. Edited by Pablo Bertrand and Ignacio Sánchez, renowned academics and pediatricians from the Pontifical Catholic University of Chile, it encompasses five sections and 74 chapters, presenting and discussing the most important topics related to pediatric respiratory diseases. Written and presented in a simple and didactic format, it intends to ease learning and settlement of doubts in pediatric respiratory diseases. The reader is naturally introduced into the physiology, diagnosis, syndromes, diseases and the treatment associated with the respiratory pathologies affecting children. The chapters include algorithms for the treatment of various syndromes and updated treatment proposals grounded in evidence-based medicine for more than 50 pulmonary diseases. Pediatric Respiratory Diseases – A Comprehensive Textbook is an essential reference for the proper clinical approach to respiratory diseasesin children. It is intended for all interns, residents and fellows with interest in pediatric pulmonary medicine, as well as practicing physicians, general practitioners, pediatricians and pulmonologists who face pediatric respiratory disorders in daily clinical practice.

This book provides an innovative and comprehensive overview of the relationship between lung and exercise, both in healthy, active subjects and in subjects with chronic respiratory diseases. It investigates in detail the central role of the lungs during exercise and illustrates the impact of respiratory impairment due to both acute and chronic lung diseases on performance. Further, the book presents the latest evidence-based findings, which confirm that exercise is an effective and safe form of prevention and rehabilitation in respiratory diseases.The first section describes the changes in the respiratory system during exercise and the contribution of respiration to exercise, while readers will learn how to perform a respiratory assessment in the second section. The third section addresses a broad range of chronic respiratory diseases and the (in)ability of those affected to play sports and perform exercise, thus providing a basis for individual assessments. The last two sections focus on respiratory training, rehabilitation and the relationship between respiration and the environment, e.g. in high-altitude and underwater sports. The book will appeal to a wide readership, including pulmonologists, sport medicine physicians, physiotherapists and trainers, as well as instructors and students in exercise science.

This book presents a clear and concise summary of the clinical tenets of lung transplantation with an update on recent developments in the field. It examines the operational principles which underpin successful lung transplantation and shows how an evidenced based approach combined with wisdom borne of experience leads to better outcomes in day-to-day management. Focused on simplicity and elegance of style with ample visual images, this book provides a unique overview of trends and strategies for the best outcomes in lung transplantation. Approachable and easily digested, this book will be a go-to resource for professionals seeking a succinct and well-illustrated guide to this growing area of surgical transplantation.

This book is a comprehensive and authoritative source on nontuberculous mycobacterial (NTM) pathogens and diseases and their appropriate management, with a focus on lung disease. NTM diseases, especially lung diseases, are increasing in prevalence in the U.S. and internationally with concomitant growing interest in a broad section of the medical community. Often merely included in coverage of tuberculosis, many aspects of NTM organisms and diseases are actually very different than TB. These differences are not intuitive or trivial and frequently result in suboptimal management of NTM patients. This book addresses these gaps in the literature with chapters on microbiology, pathophysiology, epidemiology, the various diseases that can stem from NTM, and their particular management. There is also coverage on prevention and NTM as a public health problem. For pulmonologists and infectious disease physicians, this is the definitive resource on nontuberculous mycobacteria.

Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.

Now in a fully updated 9th Edition, Kendig's Disorders of the Respiratory Tract in Children, by Drs. Robert Wilmott, Andrew Bush, Robin Deterding, and Felix Ratjen, continues to provide authoritative, evidence-based information to residents, fellows, and practitioners in this wide-ranging specialty. Bringing key knowledge from global experts together in one easy-to-understand volume, it covers everything from the latest basic science and its relevance to today's clinical issues, to improving patient outcomes for the common and rare respiratory problems found in newborns and children worldwide. - Uses succinct, straightforward text, numerous tables and figures, summaries at the end of each chapter, and more than 500 full-color images to convey key information in an easy-to-digest manner. - Contains new chapters reflecting expanding knowledge on the respiratory complications of Down syndrome and other genetic disorders, modern molecular therapies for cystic fibrosis and asthma, and pulmonary embolism and thromboembolic disease. - Includes access to a new video library with demonstrations of key procedures. - Features a new templated format with more descriptive headings and bulleted text for quick reference and navigation. - Covers today's key issues, including the genetic basis of respiratory disease, new and emerging respiratory infections, interstitial lung diseases in infants and young children, technology and diagnostic techniques for pulmonary function tests, emerging lung infections, and new therapies for cystic fibrosis and asthma. - Provides up-to-date instruction on important procedures, such as bronchoscopy and pulmonary function testing. - Highlights the knowledge and expertise of three new editors, as well as more than 100 world authorities in the fields of pediatrics, pulmonology, neurology, microbiology, cardiology, physiology, diagnostic imaging, critical care, otolaryngology, allergy, and surgery. - Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

This book serves as a unique, comprehensive resource for physicians and scientists training in pulmonary medicine and learning about pulmonary function testing. Pulmonary function testing and the physiological principles that underlie it are often poorly understood by medical students, residents, fellows and graduate students training in the medical sciences. One reason is that students tend to get overwhelmed by the basic mathematical descriptions that explain the working of the respiratory system and the principles of pulmonary function testing. Another reason is that too many approaches focus on the math without explaining the clinical relevance of these principles and the laboratory testing that enables us to measure the very lung function that these principles are describing. This book answers that need by providing a series of chapters that guide the reader in a natural order of learning about the respiratory system. In particular, after a generaloverview of the structure-function design of the lung and the history of pulmonary function testing, authors begin with the drive to breathe, and then follow the pathway of air as it is drawn into the lung, undergoes gas exchange, and is then exhaled back out again. Each chapter focuses on the key principles and corresponding pulmonary function tests that explain each step in this pathway. Each chapter is written by at least two experts, one with expertise in the underlying physiology, and the other with expertise in the clinical testing and application of pulmonary function testing in practice. Many figures and tables highlight key points, and multiple case studies in each section provide specific examples of the clinical application of each pulmonary function test. This is an ideal guide to pulmonary function tests for practicing pulmonologists, residents, fellows, and medical students.

This new rapid reference guide provides the latest information on common respiratory disorders seen in practice, with full coverage of asthma management, sleep disorders, and more. Includes more than 100 images to aid in problem-solving and diagnosis! Content is presented in a concise, bulleted template featuring algorithms, tables, and figures that make it easy to find key information to aid in diagnosis and treatment.Topics include:Evaluation of Children With Respiratory DiseaseAnatomic Disorders and Congenital Anomalies of the Airway, Lungs, Pulmonary Vessels, and Chest Wall Asthma and Related ConditionsInfections of the Respiratory TractPulmonary Function TestingPharmacological ManagementPulmonary and Respiratory ImagingBronchoscopyPediatric Sleep MedicineSpecial expanded sections on asthma, sleep medicine, and respiratory care provide non-specialists with the knowledge needed to effectively treat these often-complicated conditions. Each chapter is presented in a concise, bulleted format with tables and figures that make it easy to locate key information. Also included is direction on when to refer patients who require the care of a pulmonary specialist.

Bronchiectasis is a hot topic in respiratory medicine, attracting an increasing amount of interest from clinicians, scientists, physiotherapists and the pharmaceutical industry. However, there is a lack of knowledge about the disease in terms of the research performed, clinical management, classification and patient treatment. The disease is also very complex because it can be caused by multiple underlying disorders, meaning its clinical presentation is highly diverse. This Monograph will tackle these issues by providing a series of chapters from recognised world experts covering: clinical management, service delivery, pathophysiology, microbiology and underlying disorders. The book also addresses the challenges faced in clinical trials and the need for drug development, and presents a number of clinical cases designed to aid learning. The Bronchiectasis Monograph substantially integrates the 2017 ERS guidelines on management of these patients. It is an essential reference for anyone caring for bronchiectasis patients or engaged in bronchiectasis research.

Véritable traité par son ampleur, cette nouvelle édition de Pneumologie pédiatrique témoigne des progrès réalisés ces dernières années aussi bien dans les explorations que dans la prise en charge. Notamment, la génétique et l'immunologie contribuent à affiner les connaissances sur les pathologies interstitielles, les maladies inflammatoires, les dyskinésies ciliaires, la mucoviscidose ou les pathologies vasculaires pulmonaires. L'imagerie, IRM et imagerie prénatale, améliore également le diagnostic des pathologies pulmonaires, de même que les données issues de la recherche fondamentale. Synthèse pratique et complète, depuis la sémiologie aux prises en charge spécifiques, l'ouvrage couvre l'ensemble des thèmes de la pneumologie pédiatrique : signes d'appel • outils diagnostiques • pathologie infectieuse • pathologie immuno-allergique • anomalies du développement • mucoviscidose • dyskinésie ciliaire primitive • pathologies infiltratives diffuses • poumon tumoral • poumon et autres pathologies • poumon aigu et poumon toxique • prises en charge spécifiques. L''ouvrage comprend en outre une riche iconographie (imagerie, histologie, schémas), des tableaux, des points clefs à la fin de chaque chapitre soulignant les messages essentiels. Un site compagnon en ligne propose également des vidéos et des bibliographies complémentaires. Cet ouvrage, dirigé par les Professeurs Jacques de Blic et Christophe Delacourt, tous deux Professeurs des Universités et Praticiens hospitaliers dans le service de Pneumologie et Allergologie pédiatriques à l'hôpital Necker-Enfants malades (Paris), est le fruit de la collaboration de plus de cent quarante auteurs, tous spécialistes reconnus de leur discipline

The latest edition of this popular book covers the “how-to” of respiratory care of newborns. Chapters from the previous edition have been updated to reflect advances in both equipment and practice, while newer chapters reflect the evolving worldwide approaches to neonatal respiratory failure, such as sustained inflation, optimization of lung volume, and the use of volumetric capnography, aerosol therapy, and management of chylothorax. New additions to the book also include chapters on assessment of large data bases, implementation of quality improvement programs in neonatal respiratory care, chronic ventilation of the baby with non-respiratory failure. The text also features case studies for self-review and is illustrated with high quality radiographic images, figures, tables, and algorithms. Written and edited by international experts, the Manual of Neonatal Respiratory Care, Fourth Edition is a thorough update and remains a convenient source of practical information on respiratory physiology, exam techniques, tips for performing procedures, radiography, ventilation, pain management, transport, and discharge planning.

• Divided into two volumes containing 163 chapters in total. • Completely revised edition with updated information, referenced with most recent citations. • Specifically focuses on pathophysiology, pulmonary interventions, newer diagnostic techniques and treatment modalities. • Contains separate sections on respiratory history, physiology, pharmacology, radiology and diagnostic techniques. • Includes chapters on pulmonary perspectives such as history, ethics and economics. • Aims to provide comprehensive but concise information, using a large number of tables, figures and flow charts. • The chapters are written by over 200 contributors from different countries, including India, America, Europe, South Africa, Japan, and Middle East. • Useful to the educators, pulmonologists, intensivists, thoracic surgeons, pediatricians, clinical practitioners, who are treating the patients with lung involvement; and also for the postgraduate students.

Lung Transplantation: Principles and Practice covers the current practice in donor and recipient management as well as current treatment strategies and outcomes. With 39 chapters from international experts in the field, this book covers the current practice in donor and recipient management as well as current treatment strategies and outcomes. It discusses significant advances achieved in the past decade in areas such as donor allocation, organ preservation and management, recipient selection, management and support, surgical and critical care techniques, immune suppression, and infection prophylaxis. Specific instances of pulmonary disease that commonly necessitate lung transplantation are also covered.

Lung Transplantation: Principles and Practice covers the current practice in donor and recipient management as well as current treatment strategies and outcomes. With 39 chapters from international experts in the field, the book is divided into four broad sections: General Topics, Donor Management, Recipient Management and Outcome, and the Future of Lung Transplantation. The book discusses significant advances achieved in the past decade in areas such as donor allocation, organ preservation and management, recipient selection, management and support, surgical and critical care techniques, immune suppression, and infection prophylaxis. Specific instances of pulmonary disease that commonly necessitate lung transplantation are also covered. Generously illustrated in full color, this valuable resource is relevant to both specialists and other providers who may refer or care for patients before and after transplantation.

This book presents a comprehensive overview of the current understanding of the organization of endogenous lung stem and progenitor cell compartments during fetal lung development, postnatal lung growth and in adulthood. Progressing stage by stage, the chapters on fetal lung development emphasize the integrated role of epithelial, stromal, vascular and neural cell elements in building a functional lung, while the subsequent chapters on adult lung regeneration describe the nature and properties of adult lung stem/progenitor cells distributed along the proximal-distal axis of the airway tree. The chapters on regulation of lung regeneration and repair discuss how regenerative cells interact with their niche microenvironment and how regulation of lung regeneration and repair in the steady state and following injury recapitulates ontogeny. And, lastly, the chapters on cellular therapies for lung disease and bioengineering the lung focus on promising emerging therapies and approaches in lung regenerative medicine. The scope of this volume of the Stem Cell Biology and Regenerative Medicine series focuses on exploring the topic of building and rebuilding the lung from a cellular rather than a molecular perspective. Thus, the section on cellular therapies does not include extensive coverage of each of the numerous lung diseases, including cancer, which could be amenable to stem cell-based therapies, although the final chapter does include some discussion on the future prospects and challenges. All of the contributors are working on the cutting edge of the lung stem cell field, making this book essential reading for those with an interest in the field of lung stem cell biology and the potential role of cellular therapies and tissue bioengineering approaches in lung regenerative medicine, including biomedical scientists, graduate students, post-graduate researchers and respiratory clinicians.

Hodson and Geddes'Cystic Fibrosis provides everything the respiratory clinician, pulmonologist or health professional treating patients needs in a single manageable volume. This international and authoritative work brings together current knowledge and has become established in previous editions as a leading reference in the field. This fourth edition includes a wealth of new information, figures, useful videos, and a companion eBook. The basic science that underlies the disease and its progression is outlined in detail and put into a clinical context. Diagnostic and clinical aspects are covered in depth, as well as promising advances such as gene therapies and other novel molecular based treatments. Patient monitoring and the importance of multidisciplinary care are also emphasized. This edition: Features accessible sections reflecting the multidisciplinary nature of the cystic fibrosis care team Contains a chapter written by patients and families about their experiences with the disease Includes expanded coverage of clinical areas, including chapters covering sleep, lung mechanics and the work of breathing, upper airway disease, insulin deficiency and diabetes, bone disease, and sexual and reproductive issues Discusses management both in the hospital and at home Includes a new section on monitoring and discusses the use of databases to improve patient care Covers monitoring in different age groups, exercise testing and the outcomes of clinical trials in these areas Includes chapters devoted to nursing, physiotherapy, psychology, and palliative and spiritual care Throughout, the emphasis is on providing an up-to-date and balanced review of both the clinical and basic science aspects of the subject and reflecting the multidisciplinary nature of the cystic fibrosis care team.

Ideal for fellows and practicing pulmonologists who need an authoritative, comprehensive reference on all aspects of pulmonary medicine, Murray and Nadel's Textbook of Respiratory Medicine offers the most definitive content on basic science, diagnosis, evaluation and treatment of the full spectrum of respiratory diseases. Full-color design enhances teaching points and highlights challenging concepts. Understand clinical applications and the scientific principles of respiratory medicine. Detailed explanations of each disease entity allow you to work through differential diagnoses. Expert Consult eBook version included with purchase. This enhanced eBook experience offers content updates, videos, review questions, and Thoracic Imaging Cases (TICs), all of which are easily navigable on any device for access on rounds or in the clinic. Includes more than 1,000 figures and over 200 videos and audio files. Key Points and Key Reading sections highlight the most useful references and resources for each chapter. An expanded sleep section now covers four chapters and includes control of breathing, consequences of sleep disruption, as well as obstructive and central apnea. New chapters in the Critical Care section cover Noninvasive Ventilation (NIV) and Extracorporeal Support of Gas Exchange (ECMO). New chapters focusing on diagnostic techniques now include Invasive Diagnostic Imaging and Image-Guided Interventions and Positron Emission Tomography, and a new chapter on Therapeutic Bronchoscopy highlights the interventional role of pulmonologists. Embedded videos feature thoracoscopy, therapeutic bronchoscopy, volumetric chest CT scans, and more. Brand-new audio files highlight normal and abnormal breath sounds and the separate components of cough.

Over the past 20 years, diagnostic tests for pediatric pulmonologists have revolutionized care of children afflicted with respiratory disorders. These tests have been used to not only help in diagnosis, but also in the management and treatment of these children. Bronchoscopic, imaging and physiologic advances have improved clinical care of these children and have been used as outcome measures in research trials. Diagnostic Tests in Pediatric Pulmonology: Applications and Interpretation describes the various diagnostic modalities (especially the newer ones) that are available for the evaluation of pediatric respiratory disorders. It also provides an understanding of the advantages and limitations of each test so that the clinician may choose the most appropriate ones. An internationally renowned group of authors describe how best to interpret the key findings in a variety of tests as well as the possible pitfalls in incorrect interpretation. This volume focuses on the main diagnostic modalities used in the evaluation of pediatric patients with respiratory disorders and presents up-to-date information on the advantages and limitations of each test for a variety of conditions encountered in the practice of pediatric pulmonology. Clinical utility of these tests is also highlighted. This valuable resource is well suited to practicing clinicians, including pediatric pulmonologists, pediatricians and primary care practitioners, as well as trainees, respiratory therapists and clinical researchers.

Turn to the field's definitive text for a thorough understanding of the clinical and scientific aspects of pulmonary medicine Since 1980, Fishman's Pulmonary Diseases and Disorders has delivered unparalleled coverage of pulmonary medicine and the underlying basic and applied science upon which clinical practice is based. The Fifth Edition, with 270 contributing authors, includes over 2,000 illustrations, 60 videos, and 18,000 references. The book opens with a comprehensive overview of the scientific basis of lung function in health and disease. It then provides detailed coverage of the broad array of diseases and disorders affecting the respiratory system, including obstructive and restrictive diseases, pulmonary vascular disorders, sleep-disordered breathing, lung neoplasms, respiratory infections, and respiratory failure, among others. The Fifth Edition has been completely updated to reflect the many advancements that have been made in pulmonary medicine over the past few years, including: Molecular development of the lung Stem cells and respiratory disease Genetics of pulmonary disease and the growth of personalized medicine Technical advances in lung transplantation Growth in immunology and immunosuppressive management Diagnosis and treatment of pulmonary hypertension Circadian rhythms and sleep biology Rapid evolution in lung imaging techniques, including functional imaging Contemporary interventional bronchoscopic techniques You will also find state-of-the-art coverage of the latest topics in critical care medicine, including: Early diagnosis and management of sepsis Multiple organ dysfunction syndrome (MODS) Acute respiratory distress syndrome (ARDS) Management of agitation and delirium in the ICU The newly defined entity of'chronic critical illness'

Cystic Fibrosis (CF) is a multi-system disorder, requiring not just respiratory expertise but also management of nutrition, diabetes, musculoskeletal and psychosocial issues. This pocketbook is a concise companion for all health care professionals who manage patients with CF. The book covers all aspects of care, including both paediatric and adult-specific issues, and summarizes up-to-date literature in a concise and focussed style. There is an emphasis on the practical aspects of management with separate chapters covering the effects of CF in the lung, the microbiology of pulmonary CF, and management of exacerbations. Psychosocial aspects of CF care, end of life care and lung transplantation are also covered, and potential future therapies reviewed. This second edition has been extensively updated to reflect the UK CF Trust Standards of Care, treatment guidelines and Cochrane reviews. There are updates on emerging organisms; an expanded section on physiotherapy; and a new Pharmacopeia that covers all common CF medications.

Drs. Nici and ZuWallack have assembled an expert team of authors covering topics such as: The history of pulmonary rehabilitation, The systemic nature of chronic lung disease, Evidence-based outcomes from pulmonary rehabilitation in the COPD patient, Location, duration and timing of pulmonary rehabilitation, Exercise training in pulmonary rehabilitation, Strategies to enhance the benefits of exercise training in the respiratory patient, Collaborative self management and behavior change, Approaches to outcome assessment in pulmonary rehabilitation, and more!

Das Referenzwerk zur pädiatrischen Pneumologie wurde von einem neuen Herausgeberteam grundlegend überarbeitet. Spezialisten aus Deutschland, Österreich und der Schweiz haben bei diesem umfassenden Praxisbuch mitgewirkt, das sich an dem European Training Syllabus der European Academy of Paediatrics orientiert. Lückenlos präsentiert das Buch das fundierte Spezialwissen zu Atemwegserkrankungen bei Kindern und Jugendlichen von den respiratorischen Erkrankungen des Früh- und Neugeborenen bis hin zu Asthma, obstruktiven Atemwegserkrankungen, Pneumonie und seltenen Lungenerkrankungen. Der Bogen wird gespannt von den verständlich dargestellten Grundlagen des gesunden Respirationstraktes über die diagnostischen Techniken bis hin zu den Erkrankungen des Respirationstraktes, die nach einer einheitlichen Struktur ausführlich und praxisnah beschrieben sind.Spezielle Therapien wie Inhalationstherapie oder Heimbeatmung bilden einen weiteren Schwerpunkt des Buches. Das wichtige Themader Interaktionen mit anderen Fachgebieten wurde neu ins Buch aufgenommen, darunter intensivmedizinische Aspekte, Difficult Airway Management oder kinderchirurgische Aspekte. Damit ist dieses Referenzwerk für alle Ärzte nützlich, die mit pädiatrischer Pneumologie in Berührung kommen. Zum Lesen, Lernen und Nachschlagen.

Although respiratory syncytial virus (RSV) has been a high priority for vaccine development for over 50 years now, still no vaccine is available and none has yet demonstrated sufficient promise to move to licensure. The success of RSV immune prophylaxis and the availability of ever more powerful tools to study the immune response and pathogenesis of disease, combined with the ability to construct a wide variety of vaccines using different vaccine platforms, give us grounds to believe that an RSV vaccine is within reach. This book brings together in one source what is currently known about the virus: its clinical and epidemiologic features; the host response and pathogenesis of the disease; vaccines, vaccine platforms, and treatment; and animal and tissue culture models of RSV infection. It is designed to organize the critical information relevant to RSV vaccine development, facilitate the assimilation of data, and speed progress toward producing a safe and effective vaccine.

Respiratory syncytial virus (RSV) is an important respiratory pathogen of infants and young children and is the most common cause of lower respiratory tract infection-related hospitalization of children under the age of one. In this book, the authors present current research in the study of the prevention, diagnosis and treatment of RSV. Topics discussed include the genetic variables that play a role in the presentation and the outcome of severe RSV disease; cellular immunity and immunoproteomics of HLA class I ligands in HSRV infection and recurrent infections, chronic sequelae, and risk factors for RSV.

Kendig, Chernick's Disorders of the Respiratory Tract in Children is the definitive medical reference book to help you confront critical challenges using the latest knowledge and techniques. You'll get the state-of-the-art answers you need to offer the best care to young patients.Tackle the toughest challenges and improve patient outcomes with coverage of all the common and rare respiratory problems found in newborns and children worldwide. Get a solid foundation of knowledge to better understand and treat your patients through coverage of the latest basic science and its relevance to clinical problems. Get comprehensive, authoritative coverage on today's hot topics, such as interstitial lung disease, respiratory disorders in the newborn, congenital lung disease, swine flu, genetic testing for disease and the human genome, inflammatory cytokines in the lung, new radiologic techniques, diagnostic imaging of the respiratory tract, and pulmonary function tests. Learn from the experts with contributions from 100 world authorities in the fields of pediatrics, pulmonology, neurology, microbiology, cardiology, physiology, diagnostic imaging, anesthesiology, otolaryngology, allergy, and surgery.

This popular book covers the “how-to” of the respiratory care of newborns in outline format. It includes case studies for self-review and is illustrated with high quality radiographic images, figures, tables, and algorithms. Written and edited by international experts, the Third Edition is a thorough update and remains a convenient source of practical information on respiratory physiology, exam techniques, tips for performing procedures, radiography, ventilation, pain management, transport, and discharge planning.·Up-to-date clinical information from world experts·Case studies·Easy-to-consult outline format·Condensed information about all of the major mechanical ventilators (e.g., modes, displays, and alarms)“The extent of coverage, easy readability, superb organization [and] …practical pearls make [this book] worthwhile…simply a great bargain.” --Journal of Perinatology (review of a previous edition)

The first issue of Clinics in Chest Medicine to be published with this focus, this issue reviews bronchiectasis from numerous angles to provide comprehensive coverage on this important subject. Epidemiology, airway defense mechanisms, pathogenesis, imaging and genetic causes of bronchiectasis are discussed. Allergic bronchopulmonary aspergillosis is addressed, as well as non-tuberculous mycobacteria as a cause of bronchiectasis. Authors examine how to evaluate the success of therapy for bronchiectasis (what endpoints to use) and then discuss a variety of therapy options: inhaled and systemic antibiotic treatment, chest physiotherapy, pharmacologic agents for mucous clearance, antipinflammatory therapy and macrolides. Pulmonary resection and lung transplantation for bronchiectasis are reviewed. Recent advances in Cystic Fibrosis are also discussed.

Therapy in Sleep Medicine, by Drs. Teri J. Barkoukis, Jean K. Matheson, Richard Ferber, and Karl Doghrami, provides the clinically focused coverage you need for rapid diagnosis and effective treatment of sleep disorders. A multidisciplinary team of leading authorities presents the latest on sleep breathing disorders (including obstructive sleep apnea), neuropharmacology, parasomnias, neurologic disorders affecting sleep, sleep therapy for women, sleep therapy in geriatric patients, controversies, and future trends in therapy in a highly illustrated, easy-to-follow format.Diagnose and treat patients effectively with complete coverage of the full range of sleep disorders. Find diagnostic and treatment information quickly and easily thanks to a highly illustrated, easy-to-read format that highlights key details. Stay current on discussions of hot topics, including sleep breathing disorders (including obstructive sleep apnea), neuropharmacology, parasomnias, neurologic disorders affecting sleep, sleep therapy for women, sleep therapy in geriatric patients, controversies, and future trends in therapy. Tap into the expertise of a multidisciplinary team of leading authorities for well-rounded, trusted guidance.

This book published in two volumes. Both volume divided in twenty three sections, all sections and chapters are most important. The Textbook of Pulmonary and Critical Care Medicine also offers a unique exposure to the problems in many parts of the world. Tuberculosis, the “number one” treatable condition has been extensively covered; and special topics such as multi-drug resistance, directly observed therapy, TB prevention, nonpharmacologic approaches and extapulmonary tuberculosis are particularly relevant. Many countries are facing a growing burden of noncommunicable respiratory diseases. They have become the second leading cause of death after injuries, and their impact on indirect costs such as loss of work and home productivity is enormous. These problems are addressed and measures of prevention such as smoking cessation are included. Other special challenges including topics such as indoor and outdoor air pollution, climate change, poisoning with pesticides, snakebite toxicity, pulmonary manifestations of tropical infections and industrial accidents such as the tragedy seen in Bhopal, Madhya Pradesh, with methyl isocyanate, have been well covered. However, as globalization flattens the playing field, and countries leap to industrialization, cultural beliefs, natural resources, climate and geography have slowed the pace of development in many parts of the world. Poverty leads to malnutrition, homelessness, lack of education, and poor access to health care. Overcrowded cities and rural underdevelopment are other challenges that impact health in the various parts of the world. Moreover, epidemics of HIV, drug abuse and smoking addiction take a greater toll on the population. Yes, the world is flat, but the terrain is filled with mountains and valleys and local problems demand local solutions. And these local problems need to be explored and presented with a scholarly perspective. The Textbook of Pulmonary and Critical Care Medicine has successfully incorporated these sociodemographic factors into the subject matter. The text is well-written and the chapters are carefully referenced with subjects found in all traditional pulmonary and critical care textbooks, e.g. airway diseases, interstitial lung disease, pleural disease, pulmonary neoplasia, pulmonary infection, sleep and critical care. There are several nontraditional sections as well that are practical and especially helpful to the practicing physician. These include a section on the symptom approach to lung disease, an overview of the pharmacologic agents used to treat lung disease, and a comprehensive review of methods in lung diagnosis from the simple history and physical examination to the latest complex tools of interventional pulmonology. The textbook is especially unique because of the abundance of illustrations, flow charts and tables. There are many radiographic and pathologic reproductions that are especially helpful.

You'll turn here often for the latest AAP findings and recommenations; assessment and testing how-tos; proven therapeutic strategies; procedures, and techniques; home care and monitoring considerations; and much more. Powerful problem-solving features in each information-rich chapter include illustrative case reports, key point summaries; and definitions of pulmonary-specific terms. Nearly 300 finely detailed images complement the text. Content highlights: - Foundation knowledge and know-how - anatomy and physiology; physical examination; pulmonary testing; imaging; bronchoscopy- Allergic conditions - acute bronchopulmonary aspergillosis; asthma- Anatomical disorders - congenital anomalies; chest wall and spinal deformities- Upper airway infections - croup, epiglottitis, and bacterial tracheitis- Lower airway infections - bronchiectasis; bronchiolitis; community-acquired pneumonia; complications of pneumonia; tuberculosis- Noninfectious pulmonary disorders - interstitial lung disease; bronchopulmonary dysplasia; pleural effusion; pneumothorax and pneumomediastinum; pulmonary hemorrhage; aspiration- Miscellaneous pulmonologic issues - lung transplantation; pulmonary disorders associated with obesity; functional respiratory disorders; sleep disorders- Genetic disorders - cystic fibrosis; primary ciliary dyskinesia- Lung disease associated with systemic disorders - pulmonary complications of cardiac disease; endocrine disorders; GI disorders; sickle cell disease; immunodeficiency disorders; neuromuscular disorders; cancer- Treating and managing pulmonary disease - airway clearance techniques; medication delivery; bronchodilators; antibiotics and corticosteroids; oxygen therapy; preventing and treating tobacco dependence; home monitoring; home ventilation

Murray and Nadel's Textbook of Respiratory Medicine has long been the definitive and comprehensive pulmonary disease reference. Robert J. Mason, MD now presents the fifth edition in full color with new images and highlighted clinical elements. The fully searchable text is also online at www.expertconsult.com, along with regular updates, video clips, additional images, and self-assessment questions. This new edition has been completely updated and remains the essential tool you need to care for patients with pulmonary disease.Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices.Master the scientific principles of respiratory medicine and its clinical applications. Work through differential diagnosis using detailed explanations of each disease entity. Learn new subjects in Pulmonary Medicine including Genetics, Ultrasound, and other key topics. Grasp the Key Points in each chapter. Search the full text online at expertconsult.com, along with downloadable images, regular updates, more than 50 videos, case studies, and self-assessment questions.Consult new chapters covering Ultrasound, Innate Immunity, Adaptive Immunity, Deposition and Clearance, Ventilator-Associated Pneumonia.Find critical information easily using the new full-color design that enhances teaching points and highlights challenging concepts.Apply the expertise and fresh ideas of three new editors-Drs. Thomas R. Martin, Talmadge E. King, Jr., and Dean E. Schraufnagel.Review the latest developments in genetics with advice on how the data will affect patient care.