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This book is an informal autobiography by John West MD PhD. He obtained his medical degree in Adelaide, Australia and then spent 15 years mainly at the Royal Postgraduate Medical School, Hammersmith Hospital in London where he, with others, used radioactive oxygen-15 to make the first description of the uneven regional distribution of blood flow in the lung. In 1960-1961, he was a member of the Himalayan Scientific and Mountaineering Expedition led by Sir Edmund Hillary who had made the first ascent of Mt Everest 7 years before. During the expedition about 6 scientists spent up to three months at an altitude of 5800 m studying the effects of this very high altitude on human physiology. Because of his interests in the effects of gravity on the lung, Dr. West spent a year at the NASA Ames Research Center in Mountain View, California in 1967-1968. While there he submitted a proposal to NASA to measure pulmonary function of astronauts in space, and thiswas funded. Later, in 1981 he organized the American Medical Research Expedition to Everest during which the first measurements of human physiology on the summit, altitude 8848 m, were obtained. In the 1990's, Dr. West's team made the first comprehensive measurements of pulmonary function of astronauts in space using SpaceLab which was taken up in the Shuttle.

This book consists of 23 essays about prominent people and events in the history of respiratory physiology. It provides a first-hand chronicle of the advancements made in respiratory physiology starting with Galen and the beginnings of Western physiology. The volume covers every aspect of the evolution of this important area of knowledge: pulmonary circulation, Boyle's Law, pulmonary capillaries and alveoli, morphology, gas exchange and blood flow, mechanics, control of ventilation, and comparative physiology. The book emphasizes societal and philosophical aspects of the history of science. Although it concentrates on physiology, it also describes how cultural movements, such as The Enlightenment, shaped the researchers discussed.This book is published on behalf of the American Physiological Society by Springer. Access to APS books published with Springer is free to APS members.

This companion monograph to West's Respiratory Physiology covers normal respiratory function and focuses on the function of the diseased lung. Pulmonary Pathophysiology: The Essentials offers a concise overview of the diseased states of the lung, emphasizing structure and function. The Eighth Edition is updated to include new information on asthma therapies, new radiographs and micrographs, extended sections on infections and cancer, more thorough explanations for review questions, and a new summary appendix of equations with sample calculations.

This up-to-the-minute reference provides comprehensive coverage of the behavior of the lung in the presence and absence of gravity-emphasizing the effect of gravity upon the cardiovascular, pulmonary, and lymphatic systems.Covers experiments in respiratory physiology from before the Space Shuttle Era to long-duration flights of the Internat