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Now in a fully revised and updated fourth edition, this book remains the most comprehensive resource on Prader-Willi syndrome (PWS) available on the market. There have been significant changes in the diagnosis, clinical care and treatment of PWS since the previous edition was published in 2006, and more thorough information on understanding the cause and diagnosis of the condition, along with clinical presentation and findings with natural history data now available. The book is divided into three thematic sections. Part One discusses the genetics, diagnosis, research and overview of PWS, including current laboratory testing. The medical physiology and treatment of PWS comprise Part Two, covering the GI system, obesity as well as the use of growth hormone. Part Three, the largest section, presents a wide-ranging, multidisciplinary management approach to PWS, attending to the many manifestations of the condition. Topics here include neurodevelopmental aspects, speech and language disorders, motor issues, psychological and behavioral management, educational and transitional considerations, vocational training and residential care, and advocacy for both school discipline and sexuality. Syndrome-specific growth charts, benefits eligibility information and additional resources are included in helpful appendices. Timely and well-crafted, this latest edition of Management of Prader-Willi Syndrome remains the gold standard for clinicians and health care providers working with patients diagnosed with this rare obesity-related genetic disorder.

Drogenmissbrauch in der Schwangerschaft hat negative Folgen für die werdende Mutter und ihr ungeborenes Kind. Eine möglichst frühe und umfassende Aufklärung ist deshalb eine der wichtigsten Aufgaben, die vor allem Ärztinnen und Ärzte leisten müssen, aber auch Angehörige aller Gesundheitsberufe, die Schwangere und junge Mütter betreuen. Ziel ist dabei, Mutter und Kind vor den Folgen des Drogenkonsums zu bewahren bzw. zumindest die Risiken so weit wie möglich zu minimieren. Grundlegende pharmakologische Kenntnisse der intrauterinen Exposition mit deren Langzeitfolgen und den sich daraus ergebenden therapeutischen Maßnahmen bilden die Basis zu diesen Aufgaben.

This completely revised and updated edition offers a comprehensive overview of neonatal pain assessment and treatment. It includes the field of fetal surgery, and many other topics have been updated or added, such as circumcision analgesia, new drugs, new insights into neurophysiologic pathways of neonatal pain and new drawbacks of analgesic drugs. While in the early years of the 21st century pain treatment in neonates was still optional, it is now a tenet, and more and more institutions are looking for inspiration and good references to create their own guidelines. Written by leading researchers in the field, this book provides that inspiration and offers a valuable tool for neonatologists, anesthetists, nurses and physiotherapists. Since it also deals with prenatal and postnatal surgery, it also appeals to surgeons.