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With examinations of 19 new psychiatric drugs, 19 new forms of previously available drugs, and a host of new medical agents, this third edition of the Clinical Manual of Psychopharmacology in the Medically Ill has been updated to include medical and psychiatric drugs that have become available since the publication of the second edition in 2017, as well as recent relevant randomized controlled trials, systematic reviews, and meta-analyses. Boasting all the rigor that characterized the preceding editions, every chapter in this new volume has been reviewed and revised by experts—including 11 new authors. For 15 categories of medical disorders and specialty areas that include cardiovascular disorders, oncology, obstetrics and gynecology, and substance use disorders, the book examines • Key differential diagnostic considerations • The evidence for the efficacy of psychiatric drugs in each disorder • Disease-specific side effects of psychiatric drugs • Neuropsychiatric side effects of drugs for each medical disorder • Disease-specific alterations in pharmacokinetics • Drug-drug interactions Patients with medical and psychiatric comorbidity have more functional impairment, disability days, emergency department use, and rehospitalization, as well as higher medical care costs. By examining the intersection of psychiatric and medical illness, and offering easily referenced key points for each chapter, this new edition prepares both mental health practitioners and primary care physicians and internists to more safely and effectively work with patients who have psychiatric and medical illness.

This significantly revised fourth edition provides a practically orientated guide to interactions associated with antiseizure medications. It describes pharmacokinetic and pharmacodynamic antiseizure medication (ASM) interactions, including details of the magnitude and mechanism of interactions, and also of drug combinations that are not associated with interactions and therefore can be co-prescribed without undue concern. Presented in alphabetical order and by drug class, drug interactions that occur between ASMs and also between ASMs and non- ASMs are described in three sections: Drug interactions between ASMs; Drug interactions between ASMs and non- ASM Drugs: Interactions affecting ASMs; Drug interactions between ASMs and non ASM Drugs: Interactions affected by ASMs. The latest data on all drug interactions is presented. New agents discussed include cannabidiol, cenobamate, everolimus and fenfluramine,. Antiseizure Medication Interactions: A Clinical Guide, 4th Edition concisely presents the most recent developments and data available on the topic. Therefore, enabling physicians and allied health professionals to make more rational choices when ASM polytherapy regimens are required. It will be of interest to medical professionals in disciplines including neurology, psychiatry and pediatrics.

This book provides neurologists with a basic knowledge of psychiatric medications. It begins with general principles of psychopharmacology and the frequency of psychiatric illness in neurology patients. It goes on to cover psychoactive drugs in the elderly and treating behavioral symptoms of dementia. There is a special emphasis on drug-drug and drug-diet interactions that may be seen in clinical practice. Neurologists, residents, neuropsychiatrists, neuropsychologists and psychiatrists in training will find this practical guide invaluable in numerous clinical settings.

The new edition of Clinical Manual of Psychopharmacology in the Medically Ill continues the legacy and builds on the success of the first edition by offering a thoroughly up-to-date, comprehensive, and practical guide to the prescription of psychotropic medications in patients with medical illness. The book addresses the prevalence of psychiatric illness in patients with serious medical illness, the complications that may arise, and the implications for psychopharmacological treatment. There is increasing recognition that patients with medical and psychiatric comorbidity have more functional impairment, disability days, emergency department use, rehospitalization, and other medical care costs than do those without such comorbidity. As a result, health care systems have been incentivized to develop new and innovative models of population-based care that integrate medical and psychiatric care in an effort to increase quality and prevention while decreasing use of expensive services such as emergency department visits and hospitalizations. The book is a valuable guide for clinicians across a range of specialties operating in this new, more demanding health care environment. The manual addresses critically important topics through the use of a variety of user-friendly features: • Psychiatric drugs that have become available since the first edition, as well as all recent relevant randomized controlled trials, systematic reviews, and meta-analyses, are covered thoroughly.• Each chapter addresses key differential diagnostic considerations and adverse neuropsychiatric side effects of disease-specific medications.• Disease-specific pharmacokinetic principles in drug prescribing, including interactions between psychotropic drugs and disease-specific drugs, are also addressed.• Key summary points pertaining to psychotropic prescribing in the specific medical disease(s) or specialty area covered are included at the end of each chapter, and a multitude of useful tables summarizing the most important information are provided as well.• Chapters are heavily referenced with source information should readers wish to expand their knowledge in a specific area. The chapter authors were selected for their expertise in each area, then the text was edited for consistency, clarity, and maximum utility. Clinical Manual of Psychopharmacology in the Medically Ill is a rigorous and illuminating guide to this vital topic, and clinicians from a variety of specialties will find it indispensable.

This updated third edition of a successful book is a description of both pharmacokinetic and pharmacodynamic antiepileptic drug (AED) interactions, including details of the magnitude and mechanism of interactions, and also of drug combinations that are not associated with interactions and therefore can be coprescribed without undue concern. Presented in alphabetical order and by drug class, drug interactions that occur between AEDs and also between AEDs and non-AEDs are described in three sections: Drug interactions between AEDs; Drug interactions between AEDs and non-AED Drugs: Interactions affecting AEDs; Drug interactions between AEDs and non-AED Drugs: Interactions affected by AEDs.Antiepileptic Drug Interactions: A Clinical Guide, 3rd Edition with its clear, concise and unambiguous content will allow physicians and allied health professionals to make more rational choices when AED polytherapy regimens are indicated. There is always a choice and avoiding highly interacting drugs and choosing drug combinations that are minimally interacting or do not interact should be the goal in treating patients with epilepsy. This book provides all the necessary information so as to allow this goal to be achieved and, if necessary, to aid effective management of AED interactions.

Antiepileptic Drug Interactions: A Clinical Guide, Second Edition provides a pocket-sized, systematic description of the most clinically relevant drug interactions that occur between AEDs and also between AEDs and non-AEDs. AEDs are presented alphabetically and by drug class in three sections for easy access: Drug interactions between AEDs; Drug interactions between AEDs and non-AEDs: Interactions affecting AEDs; and Drug interactions between AEDs and non-AEDs: Interactions affected by AEDs. Antiepileptic Drug Interactions: A Clinical Guide, Second Edition should help physicians make more rational choices when polytherapy regimens are indicated and should be of interest to all who treat patients with epilepsy: neurologists and neurosurgeons, trainees at all levels, general practitioners and epilepsy nurse specialists.

Drug interactions have become a significant iatrogenic complication, with as many as 5% of hospitalizations and 7,000 deaths annually attributable to drug-drug interactions in the United States. There are several reasons these numbers have increased. First, many new medications have been brought to market in recent years. Second, advances in medical care have resulted in increased longevity and more elderly patients than ever before -- patients who are more likely to be following polypharmacy regimens. Population patterns in the U.S. have amplified this trend, with aging baby boomers swelling the patient pool and demanding treatment with medications advertised on television and in print. Fortunately, drug interactions can be prevented with access to current, comprehensive, reliable information, and the Clinical Manual of Drug Interaction Principles for Medical Practice provides just that in a user-friendly format psychiatry clinicians (including residents and nurses) and forensics experts will find indispensable. With this new edition, the book has evolved from'Concise Guide'to'Clinical Manual'and offers the expanded coverage and features healthcare providers need to keep up with this critical field. The book is well organized, with major sections on metabolism; cytochrome P450 enzymes; drug interactions by medical specialty; and practical matters, such as the medicolegal implications of drug-drug interactions and how to retrieve and review the literature. In the section on P450 enzymes, each chapter addresses what the individual enzyme does and where, its polymorphisms, and drugs that inhibit or induce activity. Each chapter also includes extensive references and study cases to help the reader understand and contextualize the information. A number of additional features enhance the book's scope and utility: • The book boasts the very latest information in the area of drug metabolism, transport, and interaction.• The chapter on P-glycoprotein (a drug transporter) was expanded from the last edition to include a broader array of transport mechanisms.• The highest ethical standard was adhered to in the development of this volume, which was not supported in any way by pharmaceutical makers or distributors. All eight contributors to this excellent resource are experts in the fields they have addressed, and clinicians can trust that the information contained in the Manual reflects the very latest research. This exceptionally practical manual is essential to maintaining the highest standard of care.

A must-have resource for the doctor's office and hospital consultations, this handy pocket reference describes and catalogues the adverse effects of commonly prescribed and over-the-counter generic drugs and herbals used in psychiatry.