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Neurocognitive and neuropsychiatric disorders contribute to a substantial amount of global morbidity and, as such, the identification of their causes is paramount to understanding their underlying pathophysiology as well as treatment and prevention strategies. Infectious Diseases in Neurocognitive and Neuropsychiatric Medicine considers the many infectious diseases that have been associated with cognitive and neuropsychiatric function. In Parts I-III, each chapter focuses on a different disease to cover a range of viral, bacterial, and parasitic diseases in neurocognitive and neuropsychiatric medicine. Part IV considers infectious diseases and clinical conditions and syndromes, while Part V examines the relationship between neurocognitive and neuropsychiatric function and the microbiome and Part VI the relationship with childhood development. In addition to molecular and clinical descriptions of the infectious diseases themselves, many chapters also explore the diseases'basic epidemiological features to consider where they may be exerting the greatest impact on cognitive and neuropsychiatric function. Where they exist, the possible mitigating factors and treatments for the neuropsychiatric and cognitive dysfunction that can be associated with these infectious diseases are also explored. In doing so, this volume examines the neurocognitive and neuropsychiatric disorders associated with infectious disease to better understand the role infections play.

For the individuals experiencing them, delusions and strong beliefs can be profoundly distressing and extremely limiting to healthy living. They also present significant challenges to the mental health professionals working with these individuals—not least because there is not always consensus around what might be considered delusional. For the first time, Decoding Delusions gathers the literature and treatment guidance materials related to delusions in one place to offer clinicians an up-to-date, culturally informed, and illustrated guide to managing the spectrum of delusions and other extreme beliefs encountered in daily practice.In Part I, chapter authors define and assess delusions, examining the current research literature into their linguistic and cultural aspects, as well as the history of their treatment. Crucially, it also provides a lived-experience perspective.Part II features the insights of a series of international experts on interventions—including third-wave cognitive-behavioral models such as compassion-focused therapy—for delusional presentations that include the following: • Persecutory paranoia• Delusional jealousy• Erotomania• Capgras syndrome• Delusions of thought possession• Trauma as a pathway to delusions Readers also will find a nuanced discussion of working with patients from Japanese backgrounds that will enhance their cultural competency and encourage them to think about extreme beliefs through a cultural lens.In Part III, the chapter authors explore the management of delusions in specific settings. Examples include delusions in forensic settings and use of remote technologies such as Zoom and digital media for measurement-based care. Finally, live-action demonstrations of key clinical skills at work are provided through video clips.Unlike any other resource currently available, Decoding Delusions proposes an approach that supports the exploration of extreme beliefs with the aim not only of distress reduction but also meaningful recovery.

In different sections of this book the relationships between the patterns of psychological response in acute and chronic respiratory failure, as well as the epidemiology of neuropsychiatric disorders in ventilator management, are collected and analyzed. Main concepts such as “vulnerability to stress”, critical illness-psychological stress and susceptibility that may develop during NIV support, as well as the diagnosis of neuropsychiatric disorders in respiratory failure are also summarized. A section is devoted to the most frequent indications of NIV, also including a special use of NIV in pandemic and high-risk infections, as well as in several other conditions such as acute and chronic respiratory failures and neurological disorders. A summary of practical approaches for treatment and prevention in neurologic and psychiatric disorders during noninvasive mechanical ventilation, as well as the perspective in terms of outcomes, quality-of-life, palliative care is also given.The book is intended for all those healthcare professionals treating patients suffering from neurological or psychiatric disorders and who develop acute or chronic respiratory failure. Neurologists, psychiatrists, pulmonary critical care professionals, geriatricians, internists and psychologists will find in the book a valuable guide for their everyday clinical practice.

This book shows how psychological and social interventions can help people with psychosis. It brings together both theoretical chapters that contribute to the reconceptualization of psychosis and clinical cases illustrating how contemporary psychotherapeutic intervention models can be applied in the treatment of this mental health condition, with reflections, strategies and practical guidelines demonstrating how these models can inform professional practice in mental healthcare. Chapters brought together in this volume aim to reflect a paradigm shift in psychosis care. They present person-centered models that lead to a way of seeing, understanding and treating psychosis that is very different from the traditional biomedical model. Current authors and approaches are revolutionizing an outdated model trapped in purely pharmacological actions and tautological explanations of a biological nature, where symptom control is the basic and fundamental form of approach, and in which psychotherapeutic actions take second place as subsidiary to the former. Approaches such as Acceptance and Commitment Therapy, Acceptance and Recovery Therapy by Levels, Open Dialogue, Compassion-Centered Therapy or the Hearing Voices movement, to name but a few of those presented in this book, represent a journey of self-knowledge and learning for those recovering from psychosis, and have an intense transformative potential for the therapeutic team. The fundamental principle that guides this book is to share models belonging to psychology that aim at personal development while respecting the needs, values and goals of each person, and that can be adopted by any professional or student of clinical psychology, psychiatry, nursing, social work or any other discipline searching for more humanistic approaches to treat psychosis.

The volume summarizes the most recent advances in our understanding of the mesentery and explains the how these are important in inflammation. It comprises a series of state of the art chapters by leading authorities in each area. It explains how recent advances in our understanding of the mesenteric organ, have advanced the diagnosis and treatment abdominal and systemic conditions including cancer, inflammatory bowel disease and endocrine conditions such as diabetes, and circulatory disorders such as atherosclerosis.

The Oxford Textbook of Social Psychiatry serves as a comprehensive reference to the historical, theoretical, and practical aspects of social psychiatry, and its role in the management of psychiatric disorders. Written and edited by leading experts and rising stars in the field of social psychiatry, this textbook provides an authoritative and global look at social psychiatry, covering a wealth of topics and up-to-date research in 79 chapters. Divided into eight sections, this resource covers an overview of the history and development of social psychiatry, as well as the social world of families, culture, and identity, focusing on key issues such as globalisation, pandemics, trauma, spirituality, and gender. Clinical conditions and special vulnerable groups are also explored, with topics such as the mental health of prisoners, somatisation, and eating disorders. Case studies of specific geographical locations provide a critical overview of global mental health today and the challenges faced in different setting, such as low- and middle-income countries.

The text of choice for instructors looking for an innovative, empirically based, and practice-oriented perspective on psychopathology is now in a revised and expanded second edition with 50% new material. The volume presents state-of-the-art information on the disorders most frequently seen in clinical practice, reviewing their etiology, DSM-5 classification, symptoms and clinical features, course, epidemiology, and associated comorbidities. With the goal of integrating science and practice, each chapter also provides substantive therapeutic guidelines derived from the research. Contributors identify underlying principles of change that clinicians can draw on to improve their effectiveness and offer critical guidance for assessment, case formulation, and evidence-based intervention. New to This Edition •Chapters on new topics--suicide, sleep difficulties, and sexual dysfunction. •New chapter on schizophrenia. •Updated throughout with current theory, findings, and clinical advances. •Increased attention to transdiagnostic concerns.

Apathy is characterized by loss of motivation, decreased initiative, and emotional blunting. It is highly prevalent in neurological, and psychiatric disorders like Alzheimer's disease, traumatic brain injury, schizophrenia, Parkinson's disease, Huntington's disease, cerebrovascular disorders, and mild behavioural impairment. It has negative outcomes including impairments in activities of daily living, caregiver burden, and higher rates of institutionalization and mortality. The definition of apathy has changed over the years alongside the development of diagnostic criteria and apathy scales and measurements. Apathy is emerging as a treatment target with interest in pharmacological, non-pharmacological, and neuromodulatory treatments for apathy. There is also an increased understanding of the neurobiology of apathy with functional and structural neuroimaging research studies. This book is a comprehensive, in-depth review from experts in neurology and psychiatry. It reviews the current state of apathy in these various disorders while also summarizing apathy diagnostic criteria, scales and measurements, neuropathology, and treatments.

Gewalt und Psychose sind auf vielfältige Weise miteinander verknüpft. Die Autorinnen und Autoren setzen sich mit dem spannungsvollen Verhältnis von Psychose und Gewalt aus psychodynamischer Sicht auseinander. Sie behandeln nicht nur Gewalt, die als Bewältigungsversuch unerträglicher, zumeist reaktualisierter traumabedingter Spannungen eines psychotischen Menschen hervortritt. In ihren Blick rücken auch die Ursachen und Folgen von Gewalt, die von der Psychiatrie in ihrer institutionalisierten Funktion der Ausübung sozialer Kontrolle ausgeht. Anhand von Fallbeispielen und unter Berücksichtigung soziologischer, juristischer und klinischer Aspekte werden gesellschaftliche wie individuelle Gründe und Auswirkungen von Gewalt in Klinik, psychiatrisch-psychotherapeutischer Begegnung und psychoanalytischer Behandlung deutlich. Mit Beiträgen von Georg Bruns, Claas Happach, Peter Hartwich, Christian Maier, Thomas Müller, Andrea Pavlik-Kellersmann, Michael Putzke, Stefan Reichard, Daniela Saalwächter und Hildegard Wollenweber

This book presents an original approach to the study of psychiatry that is based on a justified epistemological position, which demands that both the natural and the human/social sciences are necessary in developing our understanding. Psychiatry as a medical specialism was constructed in the nineteenth century through the interplay of both the natural sciences and the human/social sciences. This interplay has created a hybrid discipline that spans biological and socio-cultural-historical domains, which has raised challenges for its understanding and research. This book focuses on one of the principal challenges – how can we explore mental symptoms and mental disorders as complexes of neurobiology on the one hand and meaning on the other?The chapters in this book, dedicated to Germán E Berrios, founder of the Cambridge school of psychopathology, tackles distinctive aspects of psychopathology or related areas. By means of a combination of approaches, chapters seek to unfold another element in our understanding of this field as well as raise new directions for its further study. Rethinking Psychopathology is a valuable resource for clinical psychologists and psychotherapists, psychological researchers, historians of psychology, cultural psychologists, critical psychologists, social scientists, philosophers of psychology, and philosophers of science.

Over its two editions, The New Oxford Textbook of Psychiatry has come to be regarded as one of the most popular and trusted standard psychiatry texts among psychiatrists and trainees. Bringing together 146 chapters from the leading figures in the discipline, it presents a comprehensive account of clinical psychiatry, with reference to its scientific basis and to the patient's perspective throughout. The New Oxford Textbook of Psychiatry, Third Edition has been extensively re-structured and streamlined to keep pace with the significant developments that have taken place in the fields of clinical psychiatry and neuroscience since publication of the second edition in 2009. The new edition has been updated throughout to include the most recent versions of the two main classification systems---the DSM-5 and the ICD-11---used throughout the world for the diagnosis of mental disorders. In the years since publication of the first edition, many new and exciting discoveries have occurred in the biological sciences, which are having a major impact on how we study and practise psychiatry. In addition, psychiatry has fostered closer ties with philosophy, and these are leading to healthy discussions about how we should diagnose and treat mental illness. This new edition recognises these and other developments. Throughout, accounts of clinical practice are linked to the underlying science, and to the evidence for the efficacy of treatments. Physical and psychological treatments, including psychodynamic approaches, are covered in depth. The history of psychiatry, ethics, public health aspects, and public attitudes to psychiatry and to patients are all given due attention.

The book covers important topics in the psychiatric genetics (PG) field. Many of these have been overlooked in mainstream accounts, and many contemporary PG researchers have omitted or whitewashed the eugenic and “racial hygiene” origins of the field. The author critically analyzes PG evidence in support of genetic claims which, given the lack of gene discoveries, are based mainly on the results of psychiatric twin and adoption studies. Given that the evidence in favor of genetic influences is much weaker than mainstream sources report, due to serious issues in twin and adoption research, the author points to environmental factors, including trauma, as the main causes of conditions such as schizophrenia.

This book examines sex and gender differences in the causes and expression of medical conditions, including mental health disorders. Sex differences are variations attributable to individual reproductive organs and the XX or XY chromosomal complement. Gender differences are variations that result from biological sex as well as individual self-representation which include psychological, behavioural, and social consequences of an individual's perceived gender. Gender is still a neglected field in psychopathology, and gender differences is often incorrectly used as a synonym of sex differences. A reconsideration of the definition of gender, as the term that subsumes masculinity and femininity, could shed some light on this misperception and could have an effect in the study of health and disease. This second edition of Psychopathology clarifies the anthropological, cultural and social aspects of gender and their impact on mental health disorders. It focuses ongender perspective as a paradigm not only in psychopathology but also in mental health disorders. As such it promotes open mindedness in the definition and perception of symptoms, as well as assumptions about those symptoms, and raises awareness of mental health.

Attention deficit hyperactivity disorder (ADHD) is one of the most common mental disorders affecting children and adolescents. The condition is characterized by a persistent pattern of behavioural symptoms including inattentiveness, hyperactivity, and impulsiveness associated with substantial impairment in social, academic, and/or occupational functioning. Clinical and research interest in the topic of ADHD has grown substantially in recent years but, despite this, there is still a lack of up-to-date reference texts devoted to the diagnosis, assessment, and management of patients with these conditions. Part of the Oxford Textbooks in Psychiatry series, the Oxford Textbook of Attention Deficit Hyperactivity Disorder attempts to bridge this gap by providing an authoritative, multi-disciplinary guide to the latest research developments in the diagnosis, assessment, and management of patients with ADHD. Organized into eight key sections, this textbook covers the aetiology, pathophysiology, epidemiology, clinical presentation, co-morbidity, clinical assessment, and clinical management of ADHD. Individual chapters address key topics such as the clinical assessment of ADHD in adults, and contain information on best practice, current diagnostic guidelines including DSM-5 and ICD-11, and key up-to-date references for further reading. Edited and written by an international group of recognized experts, the Oxford Textbook of Attention Deficit Hyperactivity Disorder is a comprehensive resource suitable for child and adolescent psychiatrists, adult psychiatrists, and psychiatric trainees, as well as child psychologists, paediatricians, psychiatric nurses, and other mental health care professionals.

This book comprises succinct, accessible clinical cases in neuropsychiatry. Each clinical case has a specific and practical learning point, concerned with assessment, diagnosis, treatment or general approach. Each case models clinical reasoning and shows how the'puzzle'in the case changed the future practice of the author. Neuropsychiatry Case Studies is divided into sections relating to specific areas of neuropsychiatry, including dementias, movement disorders, autoimmune encephalopathies and epilepsy, amongst others. This book is aimed at trainee doctors in neurology and psychiatry and will also be of interest to fully trained doctors, nurses, psychologists and other allied health professionals working in this area.​

Psychiatric symptoms are common in the neurological and geriatric care of patients with Parkinson's disease. This book assembles short reviews from experts in the field to chart the various psychiatric syndromes known in Parkinson's disease, their presentation, etiology and management. Presented are special topics on epidemiology of psychiatric symptoms, affective disorders and apathy, early cognitive impairment through to dementia, visuoperceptual dysfunction, psychotic disorders, sleep disturbances, impulse disorders and sexual problems. Further, rarely discussed issues, such as the relationship between somatoform disorders and parkinsonism are reviewed. This publication is essential reading for old age psychiatrists, gerontologists and neurologists who work with patients suffering from Parkinson's disease. In addition, health practitioners who deal with senior patients, as well as scientists who need a quick update on the progress in this important clinical field will find this volume a helpful reference.

In this volume there is a strong emphasis on translational science, with preclinical approaches suggesting new directions for development of new treatments. Individual chapters describe how neuroimaging, neuroendocrine, genetic and behavioral studies use powerful research tools that are offering a completely new understanding of the factors that increase vulnerability to ADHD. The clinical impact of co-morbid problems, especially obesity and substance misuse, are highlighted and explain what such problems can tell us about the etiology of ADHD, more generally. Reviews of the pharmacology of established drug treatments for ADHD justify an exciting novel theory for their therapeutic actions and address questions about the effects of their long‑term use.

Worldwide longitudinal studies performed since the 1970s have clearly shown that ADHD persists into adulthood. These findings have stimulated researchers to develop the therapeutic approaches for adult patients, especially in European countries where scientific and clinical interest in ADHD has increased. In this volume, leading experts from Europe and the United States present their long-term results in order to provide an overview of important aspects of ADHD across the lifespan. These results include epidemiology, neurobiology, psychopathology, longitudinal course, comorbidity and social impairment associated with ADHD. Topics include diagnostic problems and therapeutic options as well as molecular genetic studies. Further, morphological and functional imaging studies in adult ADHD are reviewed, as well as the very important issue of comorbidity. Providing an excellent source of up-to-date information, this publication is essential reading for psychiatrists, neurologists, geneticists, psychotherapists, physicians and other therapists working with ADHD patients.

Compiling the expertise and research of many of the most widely-cited opinion leaders in the field, this reference spans the etiology, assessment, and management of ADHD and covers all the essential data required to care for patients with this disorder including clinical definitions, psychosocial management approaches, medication dosing ranges, and

Psychische Störungen verstehen! In den letzten Jahrzehnten ist das Wissen um die neurobiologischen Grundlagen psychischer Störungen geradezu explodiert. Neurowissenschaftler, Psychiater und Psychologen sind auf dem Weg, gemeinsam die Geheimnisse rund um das Gehirn zu entschlüsseln. Und nur wer die Grundlagen kennt, kann auch verstehen, wie und warum sich psychische Störungen entwickeln. Die erste Auflage der'Neurobiologie psychischer Störungen'ist ein Meilenstein in der deutschsprachigen Fachliteratur. Das Buch bietet Ihnen Top-Herausgeber und Autoren sowie interdisziplinäre Autorenteams. Jede Störung wird sowohl von der psychiatrisch-neurowissenschaftlichen als auch von der psychologischen Seite beleuchtet. Die neuesten Entwicklungen und Erkenntnisse werden dargestellt. Im ersten Teil werden die Grundlagen der Neuroanatomie, Neurophysiologie und Neuropharmakologie aufgezeigt. Der zweite, störungsspezifische Teil behandelt sämtliche psychischen Störungen von A wie Affektive Störungen bis Z wie Zwangserkrankungen. Die'Neurobiologie psychischer Störungen'ist beides: Eine hervorragende Einführung und DAS Referenzwerk für alle Aspekte der modernen Psychiatrie.

Immer unkonzentriert und leicht ablenkbar? Gereizt, überempfindlich und desorganisiert? Und das vielleicht schon das ganze Leben lang? Aufmerksamkeits- und Aktivitätsstörungen wurden bislang vor allem mit Kindern und Jugendlichen assoziiert. Erst seit kurzem wurde klar, dass auch Erwachsene an dieser Störung leiden können und ihr soziales Leben dadurch erheblich erschwert wird. Was steckt hinter dieser Störung? Wie kann sie sich auswirken? Welche Ursachen hat sie und wie kann sie behandelt werden? Mit diesen Fragen setzen sich die Autoren auseinander und liefern einen gut verständlichen Gesamtüberblick über dieses Störungsbild bei Erwachsenen. Mit den neuesten Studienergebnissen!

Clinical Child Psychiatry, Second Edition serves as a focused text of the major problems, challenges and practices commonly encountered in clinical child psychiatry. The introductory section covers assessment of the patient, treatment planning and a review of CBT and play therapy. Each chapter in section two reviews a clinical disorder in detail, giving diagnostic criteria and clinical management advice and is enhanced by case studies. The final section covers special topics such as foster care, adoption, loss and grief, sleep disorders, forensics and socioeconomics. Clinical Child Psychiatry, Second Edition provides invaluable guidance for all practitioners: interns and residents entering the field, pediatricians and family physicians who now provide the preponderance of child psychiatric services, and experienced clinicians encountering new areas of practice. Praise from the reviews:'… the information provided is practical and presented in user-friendly fashion. The editors have done an excellent job in organizing this text. I recommend this text to interns and residents in psychiatry and child psychiatry as well as to pediatricians and general psychiatrists.'AMERICAN JOURNAL OF PSYCHIATRY (first edition review) “… useful as a reference guide. For those entering the field, it is a good book to begin with…it is easy to read and the methods used to employ this information enhance the text.'DOODY'S HEALTH SERVICES

Attention deficit hyperactivity disorder (ADHD) is a common neurobehavioral disorder affecting 5–10% of children and adolescents and 3% of adults. Attention Deficit Hyperactivity Disorder: From Genes to Patients aims to provide a comp- hensive, state-of-the-art overview of the critical aspects of ADHD, and hopefully will serve as a quick and up-to-date reference source for professionals with an int- est in ADHD. The book is divided into three major areas that follow an historical survey. The first group of chapters deals with current theories on the pathophysiology of ADHD, and focuses on neurotransmitters and the contributions and validity of animal m- els. The second section emphasizes the evaluation and treatment of patients with ADHD, from the day-to-day approach by the clinical psychologist to the more sophisticated anatomical and functional imaging strategies that have emerged in the last decade. In addition, chapters dealing with specific impairments, such as those pertaining to reading, social interaction, and working memory, are also included for more detailed analysis of these important aspects and their respective contributions to global functioning. The third and final section provides an expanded review on the pharmacotherapy of ADHD and the appropriate methods for selection of specific drugs for individual patients based on drug kinetics and gene expression. David Gozal, MD Dennis L. Molfese, PhD vii CONTENTS Dedication........................................................................................................................................... v Preface............................................................................................................................................... vii Contributors....................................................................................................................................... xi 1 Historical Aspects of Attention Deficit Hyperactivity Disorder................................... 1 Roscoe A. Dykman 2 Scanning the Genome for Attention Deficit Hyperactivity Disorder.........................

The use of neuroimaging studies in psychiatry is exploding -- and offers tremendous potential for practicing clinicians. Yet if you're like many psychiatrists, you're sometimes uncertain about which studies to use in specific situations. Until now, you've had to sort through the only information available -- technical reviews in the literature -- for guidance. But no more.Essentials of Neuroimaging for Clinical Practice is an all-in-one resource that explains how to use these powerful techniques to improve outcomes. It demystifies neuroimaging with clear, concise, and practical advice on using today's most advanced applications in the diagnostic workup of patients. This practical clinical guide will help you achieve a solid understanding of the full range of neuroimaging modalities: • Structural techniques such as computed tomography (CT) and magnetic resonance imaging (MRI) • Functional techniques such as positron emission tomography (PET), single photon emission computed tomography (SPECT), functional magnetic resonance imaging (fMRI), and magnetic resonance spectroscopy (MRS)• Other techniques such as electroencephalography (EEG) -- including quantitative EEG and event-related potentials -- and magnetoencephalography. For each modality, you'll find: • A basic review of the technique -- trace the development of each modality, and become familiar with its underlying technology.• Guidance on when to use it -- learn which techniques are best to use in specific clinical situations. • Tips for ordering studies -- discover how to write up orders to obtain the most accurate and detailed information from each study, including when to use contrast and how to determine the best acquisition parameters.• A look at its future potential in practice and research -- explore the current capabilities of each modality and the most promising strategies for improving diagnostic results. Filled with examples of real-life imaging studies, Essentials of Neuroimaging for Clinical Practice is a must-have tool for all practicing psychiatrists and psychologists. In addition, it will serve as an excellent clinical guide for residents -- and an outstanding text for courses in clinical neuroimaging for psychiatrists.

Reflecting the latest advancements in the assessment and diagnosis of substance use and comorbid disorders, this Second Edition surveys current research in the epidemiology, genetics, and management of dually-diagnosed patients-comprehensively describing the treatment of major medical disorders that are directly or indirectly related to substance abuse including alcohol-related gastrointestinal disorders, cocaine-induced cardiac disease, and hepatitis C infection.

The new edition of this definitive textbook reflects the continuing reintegration of psychiatry into the mainstream of biomedical science. The research tools that are transforming other branches of medicine - epidemiology, genetics, molecular biology, imaging, and medicinal chemistry - are also transforming psychiatry. The field stands poised to make dramatic advances in defining disease pathogenesis, developing diagnostic methods capable of identifying specific and valid disease entities, discovering novel and more effective treatments, and ultimately preventing psychiatric disorders. The Neurobiology of Mental Illness is written by world-renowned experts in basic neuroscience and the pathophysiology and treatment of psychiatric disorders. It begins with a succint overview of the basic neurosciences followed by and evaluation of the tools that are available for the study of mental disorders in humans. The core of the book is a series of consistently organized sections on the major psychiatric disorders that cover their diagnostic classification, molecular genetics, functional neuroanatomy, neurochemistry and pharmacology, neuroimaging, and principles of pharmacotherapy. Chapters are written in a clear style that is easily accessible to practicing psychiatrists, and yet they are detailed enough to interest researchers and academics. For this second edition, every section has been thoroughly updated, and 13 new chapters have been added in areas where significant advances have been made, including functional genomics and animal models of illness; epidemiology; cognitive neuroscience; postmortem investigation of human brain; drug discovery methods for psychiatric disorders; the neurobiology of schizophrenia; animal models of anxiety disorders; neuroimaging studies of anxiety disorders; developmental neurobiology and childhood onset of psychiatric disorders; the neurobiology of mental retardation; the interface between neurological and psychiatric disorders; the neurobiology of circadian rhythms; and the neurobiology of sleep disorders. Both as a textbook and a reference work, Neurobiology of Mental Illness represents a uniquely valuable resource for psychiatrists, neuroscientists, and their students or trainees.

This is a thorough revision of one of the landmark books in the field of neuropsychiatry. The authors, one a distinguished neurologist and the other an eminent psychiatrist, provide a clear, well-integrated account of the behavioral aspects of neurological conditions and the neurological aspects of psychiatric disorders. Earlier editions presented the view, then provocative, that disordered brain function underlies psychiatric illnesses. A more balanced view characterizes the Fourth Edition, in which the authors discuss the most recent data from the neurosciences and molecular biology, including changes in the brain induced by the environment and by emotions. There is also a valuable new clinical chapter on differentiating the etiologies of disturbed behavior. Avoiding the deluge of information in multi-authored volumes, this very readable text provides a consistent approach to the understanding and diagnosis of disturbances of behavior. While the book is directed toward medical students, residents, psychiatrists, neurologists, psychologists, and psychology students (particularly those taking abnormal psychology courses), it has also been used by a wide variety of health professionals and attorneys.

This volume illuminates the interplay among biological, psychological, and social-contextual processes in the development of prevalent clinical problems. Bruce F. Pennington explains the variety of methods used to investigate the mind-brain connection, including behavioral and molecular genetics, studies of brain structure and function, neuropsychology, and treatment studies. Shedding light on where mental disorders come from, how they develop, and why they are so common, the book also examines the implications for diagnosis, treatment, and prevention.

Electrodennal activity refers to electrical changes across the skin in areas of the body that are psychologically responsive. The eccrine sweat glands are the primary detenninant of electrodennal activity, and these are psychologically active especially on the palms of the hands and the soles of the feet. As a matter of convenience, electrodennal activity is most often recorded from the palms. Over the years, the electrodennal response has been known as the psychogalvanic reflex, the galvanic skin response, the skin resistance response, the skin conductance response, and the skin potential response. The tenns psychogalvanic reflex and galvanic skin response have fallen into disuse among scientists, but are still to be found in psychology text books. of its early discovery, ease of measurement, and often easily observable Because response to experimental manipulations, the recording of electrodennal activity is one of the most frequently used methods in psychophysiology. Indeed, in the early years following the founding of the Society for Psychophysiological Research, electrodennal research so dominated the field that people worried that the society was simply an electrodennal society. Although other psychophysiological techniques have emerged as equally strong contributors to psychophysiology, electrodennal research continues to be important throughout the world. As a result of this massive research investment, there has been great progress in understanding electrodennal phenomena, as well as major advances in recording methods since the phenomenon was discovered.