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Psychiatric, or psychosocial, palliative care has transformed palliative medicine. Palliation that neglects psychosocial dimensions of patient and family experience fails to meet contemporary standards of comprehensive palliative care. While a focus on somatic issues has sometimes overshadowed attention to psychological, existential, and spiritual end-of-life challenges, the past decade has seen an all encompassing, multi-disciplinary approach to care for the dying take hold. Written by internationally known psychiatry and palliative care experts, the Handbook of Psychiatry in Palliative Medicine is an essential reference for all providers of palliative care, including psychiatrists, psychologists, mental health counselors, oncologists, hospice workers, and social workers.

Mittlerweile wird die Existenz der klinischen Realität der schizoaffektiven Erkrankungen nicht mehr in Frage gestellt. Die Erfahrung des Klinikers legt nahe, dass es tatsächlich eine Zwischen- oder Übergangsgruppe zwischen schizophrenen und affektiven Erkrankungen gibt. Jules Angst sagt: »Je besser und je länger wir unsere Patienten kennen, desto häufiger werden wir die Diagnose schizoaffektive Psychose stellen.« Im vorliegenden Buch tragen namhafte Autoren die wichtigsten Aspekte der Abgrenzung, Diagnostik und Therapie bei Jugendlichen und Erwachsenen zusammen. Neben historischen, theoretisch fundierten Betrachtungen werden ausführlich klinisch-therapeutische Vorgehensweisen sowie Verlauf und Prognose beschrieben. Die dargestellten pharmakologischen Behandlungsstrategien werden durch psychodynamische Zugangswege ergänzt. Das Buch wendet sich an all diejenigen, die sich therapeutisch um schizoaffektiv erkrankte Menschen bemühen. Mit Beiträgen von: J. Angst, D. Dietrich, H. Emrich, H. Gerhardt, M. Grube, P. Hartwich, A. Marneros, K. Maurer, C. Mischnick, B. Pflug, F. Poustka, M. Preisig, J. Röder, B. Schneider, D. Schone, D. Seehuber

Affekt und Kognition werden häufig als Gegensätze gesehen. Während Affekte subjektiv aufwühlen und emotional einstimmen, sowie über Lust und Unlust entscheiden, sollen kognitive Prozesse in einem objektiven »abgeklärten« Raum der Problemlösung stattfinden. Doch Denken im affektfreien Raum ist unmöglich. Während sich die Hirnforschung lange Zeit vor allem mit der »affektfreien« Kognition und den neuronalen Schaltkreisen beschäftigte, widmen sich Neurowissenschaftler seit einigen Jahren auch den Emotionen. In diesem Buch stellen Wissenschaftler unterschiedlicher Forschungsbereiche der Psychiatrie und Psychotherapie ihre neuesten Untersuchungsergebnisse zur Diskussion.

This book addresses the unmet needs of the medical community in dealing with the psychological problems, particularly anxiety and depression, of patients diagnosed with cancer. Providing a scholarly review of the impact of cancer diagnosis on patients'emotional and psychological status, as well as the evidence that psychological factors impact cancer occurrence and biological behavior, this book explores the therapeutic implications of such converse dynamics. Chapters review financial toxicity, eHealth, palliative care, mindfulness, sleep and cancer, social support and cancer, cultural diversity, pediatric and adolescent oncology, and geriatric oncology. While intended primarily for the professional readership of oncologists, psychologists, psychiatrists, social workers, and palliative care physicians, a final chapter also provides practical information on available resources for patients. This fully updated and expanded new edition of Psychological Aspects of Cancer: A Guide to Emotional and Psychological Consequences of Cancer, Their Causes, and Their Management provides practitioners with cutting edge knowledge as well as practical information that translates into better care for patients with cancer.

Developed by a renowned group of international authors, this engaging, case-based title once again offers readers a wide range of thought-provoking case studies that reflect contemporary, challenging, hands-on clinical care. Expanded and fully updated, Endocrinology and Diabetes: A Problem Oriented Approach, 2nd Edition addresses the complete range of endocrinologic problems found in patient care, offering the reader a convenient and pointed way to solve clinical problems in a timely manner. Due to its comprehensive coverage and practical focus, this title has developed a special place in the field of endocrinology and will again be of great interest to endocrinologists, diabetologists, internal medicine physicians, family physicians, fellows, and residents. The enthusiastic reception and warm welcome of the first edition of this book was overwhelming and gratifying. Despite many standard texts that cover physiology and clinical aspects of endocrinology, this book found a special place because it focused on patient care and practical aspects of endocrine practice. In the current volume we were fortunate to again have the honor of collaboration by international authors who pride themselves foremost as clinical endocrinologists. We hope our readers will find this updated, improved edition worthwhile, and use it for the benefit of their patients.

Many people living with epilepsy also suffer from debilitating psychiatric and cognitive disorders. While these comorbidities have been recognized for centuries, their causation, and relationship to the epilepsy remains clouded in mystery. This volume highlights recent knowledge and findings as well as controversies in our current understanding of behavioral and psychiatric comorbidities of epilepsy.

Das Standardwerk zum Thema Traumafolgestörungen Umfassend: Diagnostik und Therapie des breiten Spektrums an Traumafolgestörungen Neu in der 2. Auflage: Durchgängige Aktualisierung auf ICD-11, neue Beiträge zu sexuellem Missbrauch im kirchlichen Kontext, zu Sozialrechtlichen Bedingungen der Opferhilfe und aus Perspektive von Betroffenen Erfahrungen von schwerer Gewalt und Vernachlässigung vor allem in Kindheit und Jugend können zu einer Vielzahl psychischer und psychosomatischer Symptome führen. Typische Folgen sind Probleme mit der Affektregulation, der Selbstakzeptanz, Scham- und Schuldgefühle sowie Schwierigkeiten im zwischenmenschlichen Bereich. Nicht selten leiden Betroffene auch unter körperlichen Beschwerden ohne hinreichende organische Ursache. Auch Angststörungen, dissoziativen Störungen oder Suchterkrankungen gehören zu diesem breiten Spektrum der Beschwerden, die sich unter dem Begriff der komplexen Traumafolgestörungen zusammenfassen lassen. Die Vielzahl an gleichzeitig vorliegenden Symptomen und die hohe Beeinträchtigung der Patienten stellen eine Herausforderung für Diagnostik und Therapie dar. Dieses Standardwerk bietet eine umfassende und praxisorientierte Übersicht über die gesamte Bandbreite der Folgen schwerer und langdauernder Traumatisierungen und deren Behandlung. PsychotherapeutInnen, PsychiaterInnen und TraumatherapeutInnen erhalten somit ein wertvolles Instrument an die Hand, um komplexe Traumafolgestörungen sicher zu diagnostizieren und erfolgreich zu behandeln. In der zweiten aktualisierten Auflage wurden die Beiträge überarbeitet und auf den aktuellen Stand der Forschung aktualisiert sowie an die neue Diagnoseklassifikation WHO (ICD-11), angepasst, die jetzt auch die Diagnose Komplexe Posttraumatische Belastungsstörung als eigenständige Diagnose einschließt. Das umfangreiche Standardwerk wurde um Beiträge zu Bedingungen und Folgen von sexuellem Missbrauch im kirchlichen Kontext sowie zu sozialrechtlichen Bedingungen der Opferhilfe und einem Beitrag aus Perspektive von Betroffenen ergänzt.

This volume presents a comprehensive overview of childhood trauma, considering the psychopathological definition and its neurobiological implications as well as its impact on different psychiatric disorders. The focus on childhood trauma rather than that occurring in adulthood is important due to its general “neuro-psyco-socio” and its specific biological implications, since trauma during childhood impacts directly on neurodevelopment. It has been suggested that early life stress increases vulnerability to psychiatric disorders; however, the exact mechanisms of this association are not yet completely understood. Although childhood trauma could be considered too unspecific to be an important risk factor for individual psychiatric disorders since it seems to occur across the board, it impacts differently on different psychiatric disorders, and it can modulate their clinical expression. Therefore, the assessment of early trauma needs to be included in the clinical evaluation of patients with psychiatric disorders. The volume will be an invaluable tool for psychiatrists, helping them to select suitable pharmacological, psychotherapeutic and rehabilitative treatments.

Stress has been recognized as an important factor in the development or recurrence of various mental disorders, from major depressive disorder to bipolar disorder to anxiety disorders. Stressful stimuli also appear to exert their effects by acting upon individuals with susceptible genotypes. Over the past 50 years, animal models have been developed to study these dynamic interactions between stressful stimuli and genetically susceptible individuals during prenatal and postnatal development and into adulthood. Stress and Mental Disorders: Insights from Animal Models begins with a discussion of the history of psychiatric diagnosis and the recent goal of moving toward precision psychiatry, followed by a review of clinical research on connections between stressful stimuli and the development of psychiatric disorders. Chapters are also included on neuroendocrine, immune, and brain systems involved in responses to stress. Additional chapters focus on the development of animal models in psychiatry and the susceptibility of the developing organism to stressful stimuli. Subsequent chapters are devoted to animal models of specific stress-sensitive psychiatric disorders, including schizophrenia, autism spectrum disorders, bipolar disorder, anxiety disorders, depression, and post-traumatic stress disorder. These chapters also focus on identification of promising molecular targets for development of new drug therapies. The section concludes with a chapter on animal models of resilience to stress-induced behavioral alterations as a newer approach to understanding why some animals are susceptible to stress and others are resilient, even though they are essentially genetically identical. The final chapter discusses how these basic laboratory studies are providing promising leads for future breakthroughs in the diagnosis, treatment, and prevention of mental disorders.

This volume provides an empirical and conceptual overview of advances in our understanding of impulsivity and impulsive behaviors. Prominent scientists review the range of behavioral phenomena referred to as ‘impulsive', as well as the defining features and psychological, neurocognitive and behavioral processes that underlie of the manifestation of impulsive behaviors, focussing on progress made and the questions remaining to be answered.

This book serves as a tool for general psychiatrists, medical students, residents, and fellows looking for a clinically relevant and high-yield overview of addiction psychiatry in preparation for their board exams – or for everyday clinical practice. Written by expert educators in addiction psychiatry, the text is organized by substances misused and populations affected. This book serves as both a primary learning tool for those new to the field, as well as a reference for those working in addiction treatment. Each chapter begins with summaries of high yield clinical pearls, followed by general information including treatment, and then ends with accompanying board-style review questions. The scope includes understanding substances of misuse and substance use disorders (SUDs), how to evaluate, diagnose, and monitor SUDs, how to treat SUDs both pharmacologically and behaviorally, and critical information for specific populations of patients. Absolute Addiction Psychiatry for Clinical Practice and Review is an excellent resource for all medical students, residents, fellows, and professionals taking certification exams in addiction, including those in psychiatry, addiction medicine, emergency medicine, internal medicine, pain medicine, and others. The chapter'Laboratory Testing for Substance Use Disorders'is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

The concept of executive functioning has become central in understanding normal and abnormal cognitive processes. This timely volume analyzes the diverse conditions that can result in executive function disturbances, providing research about underlying causes, exploring the differences between developmental and acquired executive'dysfunctions,'and providing approaches for the assessment of executive dysfunction both in children and in adults. In doing so, it addresses a gap in the literature in its analysis of executive function deficits and their link with psychopathology in psychiatric patients for the management of clinical symptoms and social adjustment.Among the specific topics examined: Theoretical approaches for the analysis of the diverse dysexecutive syndromes Common executive dysfunction syndromes found during childhood development: attention deficit hyperactivity disorder and autism spectrum disorders Consequences of executive function deficits in the use of information technology Executive dysfunction and personality disorders Common executive function tests, assessment issues in executive dysfunction, and cross-cultural and bilingual questions in assessment of executive dysfunction Dysexecutive Syndromes: Clinical and Experimental Perspectives expertly extends the analysis of executive functions and dysfunctions from a fundamental and clinical perspective. It is essential reading for clinical psychologists, neuropsychologists, neurologists, and psychiatrists, and graduate and post-graduate students in psychology, neurology, and the health neurosciences, as well as clinicians, counselors, and psychometricians working with neuropsychiatric assessment.

This book is the newest edition on the series ‘advances in psychiatry'. The previous 3 volumes can be found online at http://www.wpanet.org/detail.php?section_id=10&content_id=660. They were highly successful in covering a broad area of psychiatry from different perspectives and angles and by reflecting both specialized but also international and global approaches. This series have guaranteed quality therefore can be used by different scientific groups for teaching and learning and also as a means for fast dissemination of advanced research and transformation of research findings into the everyday clinical practice.

In this volume, international experts critically review cutting-edge advances in neuroprogression research. The relevance of these findings to psychiatric and neurological disorders is clarified. Potential etiopathological mechanisms of neuroprogression are described in detail. Special emphasis is placed on the role of the immune system in stress and stress-related disorders and brain-immune interactions. The epigenetic consequences of adverse experiences in early childhood, which may prelude major psychiatric disorders, are also considered. Recent research has not only provided evidence of neuroprogression in psychiatric and neurological disorders, but has shown that pharmacologic interventions have the potential to arrest this process. Advances in testing and imaging will lead to timely diagnosis and earlier treatment. Identification of neurological mechanisms alongside (epi-)genetic vulnerability markers will create truly personalized treatment programs. This book is a valuable resource for everyone who wishes to gain insight into the essential features of the neuroprogressive course of major psychiatric and neurological disorders. In particular, psychiatrists, neuroscientists and neurologists ¬ as well as immunologists, pharmacologists and molecular biologists - will find very informative chapters of direct relevance to their field.

The Comprehensive Textbook of AIDS Psychiatry: A Paradigm for Integrated Care is the first book to provide insight into the interface between the psychiatric, medical, and social dimensions of HIV and AIDS and the need for a compassionate, integrated approach to the HIV pandemic with an emphasis on humanizing and destigmatizing HIV. Drawing from the expertise of 135 contributors in clinical and evidence-based medicine, the book provides information on the prevalence, incidence, medical and psychiatric aspects of HIV, as well as on the prevention and care of persons with HIV/AIDS.

The past twenty years have seen an increased interest in the impact of traumatic stress on development. In Neuroscience of Pediatric PTSD, Drs. Carrion and Weems summarize key work done in areas pertinent to function and development. They discuss advances in the neuroscience of executive function, memory, emotional processing and associated features such as dissociation, self-injurious behaviors and sleep regulation. Each chapter is divided into three parts; pre-clinical research, adult research and developmental research. The Authors present Issues such as comorbidity and treatment and their relationship to these neuroscience findings are presented.

Das umfangreiche Nachschlagewerk von Möller, Laux und Kapfhammer darf zu Recht als Standardwerk für Psychiatrie im deutschsprachigen Raum bezeichnet werden. Die aktuelle Auflage wurde komplett überarbeitet und aktualisiert, zahlreiche Autoren tragen mit ihrem Expertenwissen dazu bei, dass sowohl Ärzte in Weiterbildung als auch Fachärzte für Psychiatrie und Psychotherapie auf alle Fragen umfassende Antworten erhalten. Insgesamt vier Bände enthalten alle Grundlagen der Psychiatrie, Prinzipien der Diagnostik und Behandlung und selbstverständlich einen umfangreichen Teil zu den einzelnen Störungen.Von der Geschichte über Klassifikation, Diagnostik und Therapie aller Krankheitsbilder bis hin zu speziellen Aspekten der Psychiatrie finden Sie hier das gesamte Wissen auf aktuellem Stand.

Autism: The Movement Sensing Perspective is the result of a collaborative effort by parents, therapists, clinicians, and researchers from all disciplines in science including physics, engineering, and applied mathematics. This book poses questions regarding the current conceptualization and approach to the study of autism, providing an alternative unifying data-driven framework grounded in physiological factors. This book reaches beyond subjective descriptions of autistic phenomena and embraces a new era of objective measurements, analyses, and statistical inferences. The authors harness activities from the nervous systems across the brain and body (often in tandem), and introduce a platform for the comprehensive personalized phenotyping of individuals with autism. The impact of this approach is discussed to advance the development of tailored treatments options, enhance the ability to longitudinally track symptomatology, and to fundamentally empower affected individuals and their families. This book encompasses a new era for autism research and treatments, and our continuous effort to collectively empower and embrace the autistic community.

Integrative Therapies for Depression: Redefining Models for Assessment, Treatment and Prevention summarizes emerging theories and research findings on various nonpharmaceutical therapies to treat mood disorders.Supported by the review of nearly 3000 scientific studies, the book describes the concepts of inflammation, genetics, hormonal imbalance, g

This book is an up-to-date, comprehensive review of the neuropsychiatry of epilepsy, by active authorities in the field, with an emphasis on clinical and management issues. A critical appraisal of the methodology and limitations of current research on the neuropsychiatry of epilepsy is provided, and unanswered questions and controversies are addressed. Pharmacological aspects of management are also discussed in order to enable the reader to manage these patients more safely. Neuropsychiatric Symptoms of Epilepsy is aimed at neurologists, epileptologists, psychiatrists and neuropsychiatrists, and will also be of interest to psychologists and neuropsychologists, research and specialist nurses, clinical researchers and methodologists.

Textbook of postgraduate psychiatry (2 volumes) is assimilated with all modern developments in psychiatry and their effects on clinical practice. Textbook of Postgraduate Psychiatry is addressed primarily to the postgraduate student in psychiatry and allied mental health fields, but it should equally serve as a good source of revision and reference to psychiatrists, who have already completed their training, and to practitioners and clinicians, and other mental health professionals. This book is divided into two volumes, which are further divided into 22 sections following as clinical examination in psychiatry and epidemiology of mental disorder, organic mental disorder and substance related disorders, schizophrenia, other psychotic disorders and mood disorder, anxiety disorders, stress related disorders, psychosomatic medicine, somatoform disorder, dissociative disorder and other related disorders, personality disorder, sexual disorder, sleep disorder and eating disorders, pregnancy and menstruation related disorders, liaison psychiatry, neuropsychiatry, psychiatric aspect of medical disorders and other related conditions, emergency in mental health, child and adolescent psychiatry, basic sciences and imaging in psychiatry, neuropsychology, research methods, statistics and genetics in psychiatry, biological therapies, psychological methods of treatment, culture, spirituality, anthropology and psychiatry, community psychiatry and psychiatric nursing, and forensic psychiatry and mental health legislation. These 22 sections cover the 82 chapters. It is also a best reference book for established practitioners across the world. The contributors include renowned authorities in the various subspecialties of psychiatry with original work to their credit as well as young, zealous psychiatrists, who are actively involved in academic life.

The intention of this unique title is to bridge the gap between psychiatry and neuroscience, allowing a fruitful dialogue between both sciences. Recognizing that psychiatry has received important contributions from the basic neurosciences and that the basic neurosciences have received inspiration and objectives from the open problems of psychiatry, Psychiatry and Neuroscience: Bridging the Divide is designed to identify the borders, trends and implications in both fields today. Comprehensive and developed by a renowned group of experts from both fields, the book is divided into four parts: Epistemological Considerations About the Study of Normal and Abnormal Human Behaviors; From Basic Neurosciences to Human Brain; Neurosciences, Learning, Teaching and the Role of Social Environment and Explaining Human Pathological Behaviors: From Brain Disorders to Psychopathology. A unique and invaluable addition to the literature in psychiatry and neuroscience, Psychiatry and Neuroscience: Bridging the Divide offers an important and clearer understanding of the relationship between psychiatry and neuroscience.

A growing body of evidence shows that physical activity can be a cost-effective and safe intervention for the prevention and treatment of a wide range of mental health problems. As researchers and clinicians around the world look for evidence-supported alternatives and complements to established forms of therapy (medication and psychotherapy), interest in physical activity mounts. The Routledge Handbook of Physical Activity and Mental Health offers the most comprehensive review of the research evidence on the effects of physical activity on multiple facets of mental health. Written by a team of world-leading international experts, the book covers ten thematic areas: physical activity and the ‘feel good'effect anxiety disorders depression and mood disorders self-perceptions and self-evaluations cognitive function across the lifespan psychosocial stress pain energy and fatigue addictions quality of life in special populations. This volume presents a balanced assessment of the research evidence, highlights important directions for future work, and draws clear links between theory, research, and clinical practice. As the most complete and authoritative resource on the topic of physical activity and mental health, this is essential reading for researchers, students and practitioners in a wide range of fields, including clinical and health psychology, psychiatry, neuroscience, behavioural and preventive medicine, gerontology, nursing, public health and primary care.

This book offers an evidence based guide for clinical psychologists, psychiatrists, psychotherapists and other clinicians working with trauma survivors in various settings. It provides easily digestible, up-to-date information on the basic principles of traumatic stress research and practice, including psychological and sociological theories as well as epidemiological, psychopathological, and neurobiological findings. However, as therapists are primarily interested in how to best treat their traumatized patients, the core focus of the book is on evidence based psychological treatments for trauma-related mental disorders. Importantly, the full range of trauma and stress related disorders is covered, including Acute Stress Reaction, Complex PTSD and Prolonged Grief Disorder, reflecting important anticipated developments in diagnostic classification. Each of the treatment chapters begins with a short summary of the theoretical underpinnings of the approach, presents a case illustrating the treatment protocol, addresses special challenges typically encountered in implementing this treatment, and ends with an overview of related outcomes and other research findings. Additional chapters are devoted to the treatment of comorbidities, special populations and special treatment modalities and to pharmacological treatments for trauma-related disorders. The book concludes by addressing the fundamental question of how to treat whom, and when.

Can the way in which we relate to others seriously affect our health? Can understanding those attachments help health care providers treat us better? In Love, Fear, and Health, psychiatrists Robert Maunder and Jonathan Hunter draw on evidence from neuroscience, stress physiology, social psychology, and evolutionary biology to explain how understanding attachment – the ways in which people seek security in their close relationships – can transform patient outcomes.Using attachment theory, Maunder and Hunter provide a practical, clinically focused introduction to the influence of attachment styles on an individual's risk of disease and the effectiveness of their interactions with health care providers. Drawing on more than fifty years of combined experience as health care providers, teachers, and researchers, they explain in clear language how health care workers in all disciplines can use this knowledge to meet their patients'needs better and to improve their health.

Stress is such an over-used word that it is at time difficult to define its core features. When is an environment stressful? What does a stressful environment do to the brain and to the body? What are the biological mechanisms by which a stressor affects us? How does stress contributes to the onset and the progression of mental disorders? How do the effects of stress change over the life-time of an individual? These are just some of the overarching questions addressed by this book, thanks to the contribution of some of the world leading experts on the neurobiology of stress at the pre-clinical and clinical levels. Topics include current advances on the neurobiology of stress on various neurobiological systems such as immune, hypothalamic-pituitary-adrenal (HPA) axis, neurogenesis and neuroplasticity, neurotransmitter (glutamate, noradrenaline, dopamine, serotonin and endocannabinoid), neuropeptides, cognition and emotional processing as well as in utero and early postnatal effects. The clinical chapters deal with the relationship of stress and mental disorders such as depression, posttraumatic stress disorder (PTSD), anxiety disorders, schizophrenia, bipolar disorder, substance abuse and addiction, dementia and age-related cognitive decline as well as resilience to stress. Thus, this book brings together some of the most updated and authoritative views on the effects of stress of brain and behavior.

The book aims to cover basic physiologic functions of melatonin, and its therapeutic applications in humans for a variety of clinically relevant disorders. This book contains chapters on the recent aspects of melatonin physiology, its receptors and their role in mitochondrial function, its immunomodulatory role and importance in seasonal dependent diseases, role in human reproduction, role in sleep, circadian rhythm and sleep disorders, role in neurologic disorders such as Parkinson's disease, Alzheimer's disease. Additionally, melatonin's therapeutic use in neurobehavioral disorders in children, migraine and tension headache is also covered in this book. Melatonin's antioxidant role in Duchenne's muscular dystrophy and in glaucoma have also been discussed in short chapters. Two major melatonin agonists, ramelteon and agomelatine are discussed extensively on their current clinical application and ongoing research. Two chapters on agomelatonin and its role in mood disorders, particularly depressive disorders, are an important feature of this book. The chapters are written by experts from the global academia recognized for their original research and published work in the field of melatonin science.

An overview of childhood traumatic exposures and their impact for health care providers - child and adolescent psychiatrists, general psychiatrists, other pediatric behavioral health providers and primary care clinicians - is presented. Most clinicians are unaware that children in the United States are exposed to trauma frequently, either as a single occurrence, or through repeated events. These exposures result in neurobiological, developmental and clinical sequelae that can undermine children's health and well-being. This issue describes the multiple types of traumatic exposures and their sequelae, methods of screening and assessment, and principles of effective prevention and clinical treatment. The volume highlights areas of particular relevance to children, such as natural disasters, war, domestic violence, school and community violence, sexual victimization, and complex trauma. Each is differentiated as a unique trauma, requiring trauma-informed systems of care to effectively meet the needs of the exposed population. Since traumatic exposure results in added risk to child well-being, the third section of the volume describes strategies for primary prevention (e.g. violence prevention) and risk mitigation (e.g. skill and resilience building strategies), as well as reviews evidence based treatments for trauma-induced clinical disorders.

PET and SPECT in Psychiatry showcases the combined expertise of renowned authors whose dedication to the investigation of psychiatric disease through nuclear medicine technology has achieved international recognition. The classical psychiatric disorders as well as other subjects – such as suicide, sleep, eating disorders, and autism – are discussed and the latest results in functional neuroimaging are detailed. Most chapters are written jointly by a clinical psychiatrist and a nuclear medicine expert to ensure a multidisciplinary approach. This state of the art compendium will be valuable to all who have an interest in the field of neuroscience, from the psychiatrist and the radiologist/nuclear medicine specialist to the interested general practitioner and cognitive psychologist. It is the first volume of a trilogy on PET and SPECT imaging in the neurosciences; other volumes will focus on PET and SPECT in neurology and PET and SPECT of neurobiological systems.

Die 4. Auflage der Psychiatrie der Gegenwart ist völlig neu konzipiert; sie umfaßt jetzt 6 Bände. Beibehalten hat man den editorischen Leitgedanken, der auch die Vorauflagen prägte: Nicht enzyklopädische Vollständigkeit, sondern der aktuelle Erfahrungsstand der Psychiatrie wird - paradigmatisch - vermittelt. Das Werk bringt zu jedem Thema eine Übersicht des wissenschaftlich gesicherten Wissens, dessen Anwendung in der Praxis sowie Brennpunkte, Entwicklungstrends, Zukunftsperspektiven des Fachs. Wesentliche Akzentsetzungen der 4. Auflage sind die internationale Vielfalt der Beiträge, die Gewichtung von'Migration, Postraumatischer Belastungsstörung - allgemein: Spezifischen Lebenssituationen', die Integration neuer Erkenntnisse etwa in der Molekularbiologie, im Bereich bildgebender Verfahren oder in der Neuropsychologie. Neu und leserfreundlich ist das zweifarbige, mit Mariginalienspalte versehene Innenlayout.

Since the very early stages of life, we all experience some form of stress. Stressors can be mild to severe and can range from unsuccessfully longing for maternal milk in infancy, to recklessly wiggling on a motorbike to be on time to watch the NBA finals on TV, to breaking up a relationship. All those events that we call “stress” have the capability of perturbing a given state of psychological and physiological equilibrium and moving it to a different level. The transition from crawling to walking has to be considered a form of stress as much as losing a job. It is through a continuous cross-talk between environmental stressors and individual adaptations that we build our personalities and our ways to cope with daily hassles. External challenges should not necessarily be regarded as “bad”, but instead seen as constructive forces forming our ability to navigate a changing world.What is stress good for? What is stress bad for? When and why do we need to be “stressed”? Should we worry about stress? When does stress equate to “normality”? When does it turn into pathology? We hope with this book to provide some answers to these fundamental questions.

Die Betrachtung der Interaktionen emotionaler und kognitiver Prozesse ist von zentraler Bedeutung für das Verständnis der menschlichen Entwicklung und des menschlichen Verhaltens sowie für das Verständnis unterschiedlicher psychiatrischer Erkrankungen. In der vorliegenden Monographie werden zunächst grundlegende Erkenntnisse zur Emotions/Kognitions-Kopplung bei Gedächtnisprozessen und deren Relevanz für affektive Störungen dargestellt. Nach einer Einführung in die Methodik der ereigniskorrelierten Hirnpotentiale werden die Möglichkeiten der Anwendung dieses Verfahrens für Fragestellungen im Bereich der Emotions/Kognitions-Kopplung bei Patienten mit affektiven Erkrankungen und bei gesunden Probanden untersucht und fächerübergreifend (Psychiatrie, Psychologie, Neurobiologie und Elektrophysiologie) diskutiert.

The German version of this work has a long tradition, and this fourth edition is the first to see an English version. Its main feature is the international approach regarding both authors and topics. The four internationally renowned editors were able to acquire the leading specialists for each field as contributors to the book. No less than 120 authors, half of them from non-German speaking countries, ensure an extremely high standard and that cross-cultural aspects are considered. Another major feature is that the book presents the evidence such that it may be examined from at least four different entry points -- via basic disciplines of psychiatric knowledge about groups defined by demographic criteria. Detailed linkages to other chapters allow the inclusion of neighbouring disciplines, such as the neurosciences and molecular biology. Contemporary Psychiatry is also unique in including chapters on psychiatric disorders caused by catastrophes, disasters etc. -- aspects totally neglected by normal textbooks. While this book gives an overall view of the state of the art of psychiatric knowledge, it even goes so far as to suggest future perspectives.

A growing body of evidence shows that physical activity can be a cost-effective and safe intervention for the prevention and treatment of a wide range of mental health problems. As researchers and clinicians around the world look for evidence-supported alternatives and complements to established forms of therapy (medication and psychotherapy), interest in physical activity mounts. The Routledge Handbook of Physical Activity and Mental Health offers the most comprehensive review of the research evidence on the effects of physical activity on multiple facets of mental health. Written by a team of world-leading international experts, the book covers ten thematic areas: physical activity and the ‘feel good'effect anxiety disorders depression and mood disorders self-perceptions and self-evaluations cognitive function across the lifespan psychosocial stress pain energy and fatigue addictions quality of life in special populations. This volume presents a balanced assessment of the research evidence, highlights important directions for future work, and draws clear links between theory, research, and clinical practice. As the most complete and authoritative resource on the topic of physical activity and mental health, this is essential reading for researchers, students and practitioners in a wide range of fields, including clinical and health psychology, psychiatry, neuroscience, behavioural and preventive medicine, gerontology, nursing, public health and primary care.

In 1970 I gave up the chairmanship of the Department of Pharmacology at Stanford University Schoel of Medicine to devote full time to basic and clinical research on problems of drug addiction. In 1971 I developed the method of radioligand binding that led to the important characterization of opioid receptors in several laboratories. The extraordinary specificity of these receptors for morphine and related opiates suggested the likelihood that there were naturally occurring morphine-like molecules in the brain and other tissues. The systematic search for these molecules culminated in 1979 in the discovery, by my group, ofthe dynorphin peptides-one of the three families of opioid peptides, the first of which (the enkephalin family) had been discovered in Aberdeen, Scotland, in 1975. I also became involved in clinical research on the pharmacologic treatment of heroin addicts, for which I established the first large methadone mainte­ nance treatment program in California. My basic and clinical research experience convinced me that an institution encompassing laboratory research, studies on normal human volunteers, and treatment research, under a single roof, could expedite progress in understanding the drug addictions. That concept was transformed into reality by the founding, in 1974, of the Addiction Research Foundation of Palo Alto, California. The funds for construction of a laboratory were provided by a generous grant from the Drug Abuse Council (a consortium of several foundations), the president of which was Thomas L. Bryant.

Trauma, Psychopathology, and Violence: Causes, Causes, Consequences, or Correlates? critically examines correlates, consequences, and potential causal relationships involving trauma, psychopathology, and violence. The authors address methodological and theoretical challenges to understanding the interrelationships among trauma, psychopathology, and violence from the perspective of their own research fields. Chapters focus on different types of traumas, traumas occurring at different developmental stages and in different contexts, and the contributions of biological and genetic factors in understanding psychopathology and violence. Each of the chapters offers recommendations for needed research. The book is divided into six topical areas: (1) Setting the context; (2) Biological and genetic factors in understanding trauma, psychopathology and violence; (3) Trauma in childhood and risk of psychopathology and violence; (4) Culture and community context in understanding trauma, psychopathology, and violence; (5) Responses to disasters and terrorism; and (6) Trauma, psychopathology, and violence in the military. The third volume in the American Psychopathological Association series, Trauma, Psychopathology, and Violence is a much needed addition to the scholarship of the mental health consequences of violence and trauma.

Recent progress in brain science has been remarkable, especially with regard to advances in the area of neuroscience. Particularly in the past decade, there have been many important discoveries about signal transduction in the brain. With this background, biological research in affective disorders has become well developed in relation to neural signaling. However, this field is fairly hard to understand comprehensively, and there is relatively little integrative work with clinical psychiatry in spite of the involvement of a wide variety of scien­ tific disciplines. This monograph brings together up-to-date reviews from several young Japanese scientists who work in basic and clinical neuroscience. The intention is to explain in plain language the information that has evolved on signal transduction in terms of the biological abnormalities and mechanisms of anti­ depressants. The model shown on the cover (and on page 24) is intended to help the reader understand signal transduction in the brain and the patho­ physiology of affective disorders as well as the mechanisms of antidepressants.

Nuclear Medicine in Psychiatry showcases the combined expertise of renowned authors whose dedication to the investigation of psychiatric disease through nuclear medicine technology has achieved international recognition. Psychiatric disorders are discussed both from categorical and functional psychopathological viewpoint and the latest results in functional neuroimaging are detailed. Most chapters are written jointly by a psychiatrist and a nuclear medicine expert, and each contains a section'Clinical Aspects', to link research data with clinical routine. This state-of-the-art compendium will be valuable to anybody in the field of neuroscience, from the psychiatrist and the radiologist/nuclear medicine specialist to the interested general practitioner and cognitive psychologist.

This book offers the most up-to-date information about research surrounding the neurobiology of bipolar disorder as well as currently available and novel therapeutic options. The volume has assembled a widely respected group of preclinical and clinical researchers who bring their expertise to bear upon this illness by reviewing cutting-edge research and clinical evidence regarding the pathophysiology and treatment of bipolar disorder. Early chapters review the course and outcome and genetics of this highly heritable condition, including chapters on epigenetics and clinical endophenotypes. Several chapters offer a remarkably thorough and unique overview of the neurobiology of the disorder, including what is known from neuroimaging work and the development of animal models. Finally, the book covers treatment strategies for bipolar disorder, including both traditional and novel therapeutics, as well as non-pharmacological treatments. It offers both researchers and clinicians key insights into this devastating disorder.

Part of the new American Pyschopathological Association Series. Containing contributions from leading scholars of causal thinking in epidemiology and psychopathology research, this volume is based on presentations at the ground-breaking 2008 meeting of the American Psychopathological Association. The authors explore the meaning of causal statements that are made from statistical and experimental evidence; then, they suggest novel approaches to analyze these statements and thus make them more informative and medically rigorous. The collection of chapters uniquely includes both methodological contributions and detailed assessments of how causal inferences can be made when considering research results on developmental psychopathology, clinical psychopharmacology, personality disorders, post-traumatic stress disorder, and psychiatric genetics. In analyzing causal references, the authors examine controversies surrounding various disorders and their treatment.

Keine Angst mehr! Viele Kinder und Jugendliche leiden unter einer Angststörung – und häufig hat sie eine Schrittmacherfunktion für weitere psychische Störungen (wie etwa Depression, Alkohol- ujnd Substanzmissbrauch). In den letzten Jahren haben sich unsere Kenntnisse über'Kinderängste'erheblich erweitert; wir wissen immer mehr darüber, wie Angststörungen entstehen, wie man sie erkennen und behandeln kann. Dieses umfassende Handbuch liefert Ihnen erstmals das komplette Wissen zu diesem Thema: Grundlagen, um Angststörungen besser zu verstehen Spezielle Angststörungen, z.B. Trennungsangst, Generalisierte Angststörung, soziale Phobie etc. Diagnostik und Therapie, für jede Störung mit konkreten und detaillierten Hinweisen Prävention Die Kapitel überzeugen durch ihre klare didaktische Aufbereitung sowie ihre verständliche und praxisorientierte Sprache. Angst lässt sich behandeln – mit diesem Buch wissen Sie wie.

Comprehensive and state of the art, the second edition of Pharmacotherapy of Depression offers major revisions of every chapter and the addition of new chapters by expert contributors. The first chapter reviews the neurobiology of depression, which lays the groundwork for understanding the mechanisms of action of antidepressants. In the next chapter, a review of the general principles guiding the diagnosis and medication treatment of unipolar depression is provided. The clinical pharmacology of antidepressants is reviewed in some detail, supplemented by tables that provide information on dosing, indications, and metabolism. Augmentation strategies are reviewed, including the use of non-traditional agents. The chapters that follow next address the use of antidepressants in special populations, such as the elderly and depressed individuals with psychosis, bipolar disorder, substance abuse, and post traumatic stress disorder. The complex issues involving the diagnosis and treatment of depression during pregnancy is thoroughly reviewed in Chapter 8 and provides a synthesis of the scientific literature in the area, one that is noted for contradictory and controversial findings, as well as guidelines for prescribing. The next chapter then provides an overview of the treatment of depression in the pediatric population, highlighting clinical concerns such as suicide risk. The book concludes with two chapters at the interface of medicine and psychiatry in the treatment of mood disorders: managing depression in primary care settings and depression associated with medical illnesses. The outstanding clinician-scientists who have contributed to this volume are all leaders in their fields and represent a broad spectrum of renowned institutions. A timely contribution to the literature, The Pharmacotherapy of Depression, Second Edition, offers busy clinicians from many disciplines a strong scientific foundation that seamlessly transitions into practical recommendations for clinicalpractice. The result is another gold-standard guide to the safe and effective use of the latest antidepressant medications.

Written in an engaging, accessible style, this book synthesizes the growing body of knowledge on the neuropsychology of emotion and identifies practical clinical implications. The author unravels the processes that comprise a single emotional event, from the initial trigger through physiological and psychological responses. She also examines how patterns of emotional responses come together to motivate complex behavioral choices. Grounded in theory and research, the book discusses relevant syndromes and populations, reviews available assessment instruments, and describes how deficits in emotional processing affect cognition, daily functioning, and mental health.

Neuroprotection is a novel perspective for the treatment of disorders that lead to neurodegeneration and disabilities as a result of deterioration of neurons due to apoptosis, oxidative stress, excitotoxicity, and other mechanisms. These mechanisms have implications not only for neurodegenerative disorders, but also for schizophrenia, mood and cognitive disorders. The purpose of this book is to provide an up-to-date overview of basic and clinical studies concerning the neuroprotective approach, mechanisms, and several compounds with neuroprotective properties that may contribute to more efficacious treatment of major mental health disorders. The book is divided into two sections. The first section serves as an introduction and overview of conceptual issues of the neuroprotective approach, and some neurobiological advances. Chapters in this section review definitions, perspectives, and issues that provide a conceptual base for the rest of the book. In addition, this part includes chapters in which the authors present and discuss the findings from basic studies of neurodegenerative mechanisms that are associated with the pathogenesis of major mental health disorders. The second section focuses on findings obtained from clinical trials with neuroprotective compounds, and neuromodulatory techniques. The take-home message is that principles of the neuroprotective approach may be applied to treatment of schizophrenia, mood and cognitive disorders. Contributors to this book are among the most active investigators and clinicians in the field who provide new perspectives not only clarifying ongoing controversies but also propose diverse aspects and new insights to neuroprotection. This book is intended for a broad readership, which includes a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, graduate students, and policy makers in the fields of mental health.

Behavioral medicine emerged in the 1970s as the interdisciplinary field concerned with the integration of behavioral, psychosocial, and biomedical science knowledge relevant to the understanding of health and illness, and the application of this knowledge to prevention, diagnosis, treatment, and rehabilitation. Recent years have witnessed an enormous diversification of behavioral medicine, with new sciences (such as genetics, life course epidemiology) and new technologies (such as neuroimaging) coming into play. This book brings together such new developments by providing an up-to-date compendium of methods and applications drawn from the broad range of behavioral medicine research and practice. The book is divided into 10 sections that address key fields in behavioral medicine. Each section begins with one or two methodological or conceptual chapters, followed by contributions that address substantive topics within that field. Major health problems such as cardiovascular disease, cancer, HIV/AIDs, and obesity are explored from multiple perspectives. The aim is to present behavioral medicine as an integrative discipline, involving diverse methodologies and paradigms that converge on health and well being.

Schizophrenia remains an important challenge to psychiatry, with its causes and underlying brain mechanisms yet to be fully revealed. Currently available treatments are neither universally effective nor without unwanted effects. These aspects, together with the high prevalence of schizophrenia, its often debilitating nature, and the associated family and social burden, make this mental disorder one of the most complex public health issues of our times. The purpose of the Advances in Schizophrenia Research series is to provide comprehensive periodic reviews of the wide range of research studies carried out around the world, with the dual purpose of solving the schizophrenia puzzle, and providing clues to new forms of treatment and prevention for this disorder. A special feature of the series is its broad scope, virtually encompassing all fields of schizophrenia research: epidemiology and risk factors; psychopathology; diagnostic boundaries; cognition; outcome and prognosis; pathophysiology; genetics; pharmacological and psychological forms of treatment and rehabilitation; community care; and stigmatization.

This book provides a detailed account of intellectual, other neuropsychological and behavioral manifestations of general pediatric diseases. The conditions discussed include the whole range of pediatric diseases - genetic syndromes, other congenital conditions, metabolic, endocrine, gastrointestinal, infectious, immunologic, toxic, trauma, and neoplastic, as well as sensory disabilities including deafness and blindness. Although the book is not intended to discuss cognitive and behavioral manifestations of conditions usually considered to be primary neurological disease, some of those, including cerebral palsy, muscular dystrophy, myotonic dystrophy and epilepsy, are included. Where possible, a'translational'approach is used, linking the behavioral and cognitive manifestations of these conditions, to the underlying structural, chemical or genetic abnormalities and their effect on the brain, and, in turn, on behavior and cognition. At the same time, included are significant psychosocial factors. Together, those factors have a major effect on patients'performance, including school performance, and on their families. This book is unique in its extensive coverage of the major pediatric conditions and of the detailed neurological, neuropsychological and behavioral aspects of each condition.

This volume provides a unique and valuable contribution to our understanding of the impact of stressful life events and mass trauma on the person, the culture and society in the course of the life span. It provides a comprehensive look at our psychological state of affairs at the beginning of the twenty-first century. There are several volumes that address some or most of these areas indivi- ally but this volume is unique in that it has brought together theoreticians, researchers and clinicians who address critical challenges in our lives. But we are now several months into the global financial crisis requiring a transition, not only for the western world but for the third world. How on earth do families in trauma zones – from Sri Lanka to Afghanistan, New Orleans to Gaza – cope with similar declining older relatives, with added traumas and zero medical resources attempt to survive? In news reports, politicians and financiers denying the inevitable and struggling for solutions that cannot be relevant to the new reality that they have yet to discover.