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Ten years have elapsed since the printing of the second edition of this book. Since then there's been a veritable explosion of information coming mainly from the field of molecular diagnostics, which bear particular importance in the classification and treatment of Infantile enteropathies, disorders associated with immunodeficiencies, the classification of intestinal polyps and polyposis syndromes in childhood, cholestatic and metabolic disorders of childhood, liver tumors and transplantation pathology, all of which were major subjects explored in our previous editions. In this updated third edition, most of the chapters have been extensively revised to incorporate updated understanding in pathogenesis and terminology. For example, the widespread use of genetic panels and next generation sequencing in the diagnosis of cholestatic disorders of infancy and childhood, not widely available when the last edition was being prepared, prompted the writing of an entirely new chapter reflecting these advances by a new set of authors. Similarly, progress in diagnosis and classification of liver tumors justified an entirely new chapter on liver tumors that incorporates newer patient stratification in treatment protocols and reflects the new WHO classification of liver tumors. Pathology of Pediatric Gastrointestinal and Liver Disease 3rd Edition provides the pediatric pathologist, the GI or general pathologist, and the pediatric gastroenterologist with the most complete and current reference on the subject. It includes in-depth discussions on disorders and issues that are frequently encountered but for which up-to-date information is often not readily available, as well as infrequent disorders unique or specific to children that are not covered in standard texts.

Pediatric Endocrinology covers all of the main aspects of translational endocrinology and clinical practice, making it an ideal resource for both paediatricians and endocrinologists. The book emphasizes the newer translational aspects of the topics covered, as well as molecular advances in diagnosis and therapy, although clinical relevance, with a particular focus on evidence-based clinical management, remains paramount. Further, transitions from childhood to adolescence and adulthood are discussed wherever appropriate. Written by a combination of respected and emerging experts in the field, this book is intended to serve as a major reference work for pediatric endocrinologists at all stages of their careers, as well as general pediatricians with an interest in endocrinology and diabetes, and endocrinologists in adult practice who may also treat children and adolescents. The book is part of the SpringerReference program, which provides access to ‘living editions'thatare constantly updated using a dynamic peer-review publishing process.

In diesem Buch vermitteln renommierte Spezialisten lückenlos und verständlich den Kenntnisstand zum Thema Kinder und Jugendliche mit Adipositas. Das Standardwerk beantwortet Fragen nach den Ursachen und dem Krankheitswert und erklärt, wie das Körpergewicht des Menschen reguliert wird. Ausführliche Informationen zur Diagnostik und zu therapeutischen Ansätzen werden mit zahlreichen Praxistipps und Beratungshinweisen ergänzt. Zusätzlich bietet das Buch Empfehlungen und Instrumente für die Betreuung Betroffener und ihrer Familien.

Dieses Buch widmet sich der bio-psycho-sozialen Erfassung, Beurteilung und Therapie belastender Krankheitssymptome und der praktischen Schmerztherapie in Rahmen der Palliativversorgung von Kindern, Jugendlichen und jungen Erwachsenen. Damit ergänzt es das bekannte Grundlagenbuch zum Thema Palliativversorgung von Boris Zernikow in idealer Weise. Der vorliegende Band ist vor allem bei der praktischen Umsetzung für den professionelle Helfer nützlich, um einem Kind mit lebensbedrohlichen oder lebenslimitierenden Erkrankungen und seiner Familie konkret und kompetent begegnen zu können.

Part of the Paediatric Psychology series Children and young people are increasingly among those being diagnosed with diabetes. However in the UK only 1 in 6 children succeed in controlling their diabetes successfully, despite support from parents and professionals. This enlightening new book is a comprehensive account of diabetes and the complex medical and psychosocial factors that influence metabolic control in children and young people. It presents a series of evidence-based and accessible educational, psychological and social approaches to increase specialist knowledge, promote positive attitudes, enhance patient care and create appropriate healthcare environments. The book offers an easy-to-comprehend approach to clinical care and includes practical tools for assessment for all healthcare professionals throughout the text. Featuring contributions from a number of international experts in the field, this thorough and wide-ranging guide is informative reading for all students, academics and professionals with an interest in paediatric psychology and health.

This book addresses and summarizes the main andrological disorders (genital, reproductive or sexual diseases) that may originate in childhood or adolescence. Since many of the andrological diseases that occur in adulthood originate before the age of 18 and sometimes even during gestation, andrological evaluation is essential during childhood to highlight anomalies in the genital organs. During puberty, evaluation can help to monitor growth and secondary sex characteristics, and to assess e.g. the possible presence of an eunucoid habitus, gynecomastia, testicular hypotrophy or varicocele, a very common pathology in young people. During adolescence, the assessment of risk factors, such as those related to certain lifestyles, is of fundamental importance for primary prevention. Moreover, in late adolescence the focus shifts to preventing sexually transmitted infections, or to dealing with possible discomforts related to the sexual sphere. Finally, ensuring young people's genital and sexual health also means protecting their fertility. Written by respected experts in the field, this book constitutes an innovative resource, combining updated, reliable and comprehensive information with agile consultation in order to provide a streamlined approach to the care of children and adolescents with such disorders.

An ideal resource for both pediatricians and endocrinologists, Sperling's Pediatric Endocrinology, 5th Edition, brings you fully up to date with accelerating research; new discoveries in metabolic, biochemical and molecular mechanisms; and the resulting advances in today's clinical care. The editorial team of world-renowned pediatric endocrinologists led by Dr. Mark Sperling, as well as expert contributing authors, cover comprehensive and current aspects of both basic science and clinical practice. Whether you're preparing for certification or have extensive clinical experience, this detailed, authoritative reference helps you increase your knowledge and determine the best possible course for every patient. - Delivers trusted guidance in every area of the field: including Endocrine Disorders of the Newborn, Endocrine Disorders of Childhood and Adolescence, and Laboratory Tests. - Features new topics such as transgender issues in children and adolescents and endocrinology of pregnancy, the fetus and the placenta. - Offers expert coverage of hot topics such as disorders of sexual development, molecular basis of endocrine disorders, hypoglycemia in newborns and infants; neonatal and other monogenic forms of diabetes; Type I and Type II diabetes and their treatment with new insulins together with the progress in an artificial pancreas and new medications for T2DM in adolescents; the obesity epidemic and role of bariatric surgery; and advances toward personalized medicine. - Includes easy-to-follow algorithms and numerous quick-reference tables and boxes in every clinical chapter, plus interactive questions online for self-assessment. - Offers state-of-the-art information and fresh perspectives from new and award-winning authors in such areas as disorders of growth, multiple endocrine tumors, and puberty and its disorders in girls and boys.

This book is aimed at primary care providers who care for the pediatric age group (general pediatrician, the PCP working with pediatric patients, and family medicine providers) with the goal of covering the endocrine differential diagnosis of common signs and symptoms of possible endocrine disease as well as appropriate initial laboratory evaluation and interpretation. While multiple pediatric endocrine textbooks exist, most of them are heavy in coverage of physiology and rare diseases, with less discussion of practical steps in evaluation and diagnosis. This book distinguishes itself through a very practical approach. The first section is organized by presenting signs and symptoms, the second section is organized by laboratory interpretation, and the third section provides summaries of common pediatric endocrine disorders. Chapters are concise, providing critical clinical information including clinical pearls, common diagnoses and important points inpatient counseling. Written by experts in the field, Endocrine Conditions in Pediatrics is a valuable resource that provides general pediatricians and other primary care providers with all of the information they need to provide superb patient care before transferring to a pediatric endocrinologist when necessary.

This IAP (Indian Academy of Pediatrics) textbook focuses on pediatric endocrinology. Endocrine system plays a critical role in physical and mental development, especially during the delicate antenatal and postnatal period as well as during adolescence. This book comprised of 21 sections, which include basics in pediatric endocrinology, clinical pointers to endocrine disorders in pediatric practice, disorders of puberty, thyroid gland and its disorders, the adrenal gland and its disorders, disorders of sexual development, disorders of water, electrolytes and acid base, disorders of calcium, phosphorus and bone metabolism, disorders of parathyroid hormone, polyglandular syndromes, hypoglycemia, diabetes mellitus, lipid disorders in children, obesity in children, low birth weight and endocrine dysfunction in postnatal life, practical protocols for dynamic testing in children, radiology in pediatric endocrinology, drugs in pediatric endocrinology, which are further divided into 60 chapters. The book covers almost all aspects of pediatric endocrinology, growth disorders and diabetes in children. This book is enriched with flowcharts, diagrams, photographs and guidelines. At the end of each chapter, there is a comprehensive bibliography to expand readers'knowledge beyond this book. The text will also be useful to DM endocrine students who have special interest in pediatric endocrinology. Postgraduates in pediatric training will also benefit from the basics written at the beginning of each chapter.

This unique book presents an up-to-date discussion of clinical disorders of the pituitary gland in children with specific emphasis on state-of-the-art diagnostic and treatment modalities, highlighting the newest scientific advances in genomics and molecular biology that clinician-scientists caring for children need to know. Chapters focus on the current knowledge base in genomics, pathophysiology, diagnosis, and medical and surgical management, organized into thematic sections. Part I discusses embryologic and genetic disorders, including genomics and congenital disorders of the pituitary. Part II presents acquired pituitary disorders, such as prolactinomas, Cushing's Disease, and both hormone secreting and non-secreting pituitary tumors. Subsequent sections cover posterior pituitary disorders, such as diabetes insipidus, functional hormone deficiencies of the hypothalamic-pituitary axis, including delayed puberty and pubertal disorders and growth hormone disorders, neuro-opthalmicdisease, CNS radiation, childhood cancer treatment and traumatic brain injury. Authoritative and comprehensive, Pituitary Disorders of Childhood will serve as a precise guide for clinical endocrinologists and will guide future investigation into translational and clinical research on the pediatric pituitary.

Das Standardwerk für die dreijährige Zusatzweiterbildung Kinder-Endokrinologie und –Diabetologie vereint zwei Subdisziplinen der Pädiatrie. Der Bogen spannt sich von den physiologischen Grundlagen bis hin zum speziellen Wissen über bestimmte Krankheitsentitäten und Untersuchungstechniken. Zudem werden Referenzwerttabellen für unterschiedliche Mess- und Laborwerte bereitgestellt.

Pediatricians face many questions and challenges during patients'transition from childhood to adulthood. Chronic diseases justify long-term medical, psychological, educational, and social management. The establishment of networks with adult endocrinologists is, therefore, very important to achieving optimal conditions for a successful transition period. In this book, leading experts discuss major public health issues such as diabetes and obesity. They also review genetic diseases, including Turner syndrome and congenital adrenal hyperplasia. All clinical cases are presented in a focused way to highlight any issues which might be discussed by the doctor with patients and family. Psychological approaches are debated as are proposals for defining specific tools to encourage autonomy during this life period. This book is a valuable tool and will be helpful in answering many questions for endocrinologists, adult and pediatric, dedicated to the long-term management of patients with chronic diseases.

Offering current guidelines on the relatively new practice of puberty suppression for gender-dysphoric adolescents, Pubertal Suppression in Transgender Youth provides a succinct, easy-to-digest overview of this timely topic. This concise, clinically-focused resource by Dr. Courtney Finlayson covers all relevant topics, from a brief history of medical care of transgender youth to emerging developments in the field. - Covers the use of gonadotropin-releasing hormone agonist (GnRHa) therapy in transgender youth, including models of care and current treatment guidelines, fertility issues, ethical considerations and the consent process, and more. - Discusses psychosocial, medical, and surgical side effects of treatment. - Consolidates today's available information on this timely topic into one convenient resource.

In diesem übersichtlichen Nachschlagewerk finden Kinder- und Jugendärzte, aber auch Allgemeinmediziner in Praxen und Kliniken die Hilfestellung, die für die praktische Tätigkeit gebraucht wird. Die allgemeine Versorgung von Kindern oder Erwachsenen wird Jugendlichen mit ihren oftmals spezifischen Problemen und ihrer besonderen Lebenssituation nicht gerecht. Das Buch unterstützt Ärzte, die Jugendliche behandeln, u.a. bei spezieller Jugendmedizin z.B. in Kardiologie, Onkologie und Neurologie, bei chronischen Erkrankungen und Transition, beim Umgang mit jugendlichen Migranten, Störungen in der Pubertätsentwicklung, Essstörungen, Verhaltensauffälligkeiten und Suchtverhalten.Das Buch ist aus dem Alltag an Praxen und Kliniken heraus entstanden, verständlich geschrieben und klar strukturiert.

This book is a comprehensive and up-to-date compendium of all aspects of brain tumors in children. After introductory chapters on the epidemiology of brain tumors, the book will provide readers with state-of-the art chapters on the principals of radiation therapy, neurosurgery and neuroimaging. Subsequent chapters discuss the biology and treatment of specific types of brain tumors. The concluding chapters present critical information relevant to survivorship, neurocognitive and other late effects, and the global challenges to better diagnosis and treatment of brain tumors in children. This book is co-authored by experts in the treatment of pediatric brain tumors. All of the authors are internationally recognized authorities and they offer an evidence-based consensus on the biology and treatment of brain tumors. This handbook has far-reaching applicability to the clinical diagnosis and management of brain tumors in children and will prove valuable to specialists, generalists and trainees alike.

Pediatric integrative medicine is a rapidly evolving field with great potential to improve the quality of preventive health in children and expand treatment options for children living with chronic disease. Many families actively use integrative therapies making familiarity with the field essential for clinicians working with pediatrics patients.This book provides a clear, evidence-based overview of the field. Foundations of pediatric health are covered with a goal of reviewing classic information and introducing emerging research in areas such as nutrition science, physical activity and mind-body therapies. Complementary medicine therapies are reviewed with an eye to expanding the conventionally trained clinician's awareness about traditional healing approaches. Clinical applications explored include: Allergy Asthma Mental health IBS Bullying Obesity Environmental health ADHD Autism The book provides an excellent introduction to a relatively young field and will help the reader understand the scope of current evidence for integrative therapies in children and how to introduce integrative concepts into clinical practice. Integrative Pediatrics is a refreshing must-read for all students and health professionals focused on pediatrics, especially those new to the field or studying at graduate level.

In diesem essential bereitet Bernhard Stier anhand von ausgewählten Fallbeispielen jungenmedizinische Fragestellungen auf, mit denen sich Ärzte in diesem Bereich im Alltag konfrontiert sehen. Ziel des Manuals ist, mit der übersichtlichen Beantwortung der wichtigsten Fragen zur Verbesserung der medizinischen Versorgung von Jungen bei Kinder- und Jugendärzten, Allgemeinmedizinern und Urologen beizutragen.

This text provides a concise, straightforward and clearly written approach for the evaluation of common topics in pediatric endocrinology. Pediatricians, family physicians, residents, fellows and medical students will benefit from the discussion of endocrine physiology and its application to common clinical practice. The text presents the major signs and symptoms and the diagnosis and management of pediatric endocrine disorders. The information presented can prepare a provider for communication with parents of a child with an endocrine condition and may allow the practitioner to avoid an unnecessary consultation. The concepts covered in the text are designed to address the first 10 headings in the content outline of the Sub-board of Pediatric Endocrinology of The American Board of Pediatrics with varying degrees of specificity. The Suggested Reading sections at the conclusion of each chapter direct the reader to outstanding larger and more detailed texts, manuscriptsand websites which offer increased detail.

Puberty is a unique paradigm for the understanding of gene-environment interaction and developmental programming. Therefore, normal and abnormal pubertal development can be divided and examined in three sections: the role of genetic factors, the role of environmental factors (including nutrition) and therapeutic issues in disorders of puberty. Dealing with all of these sections and framed along current key concepts in pediatric endocrinology, experts share their view on critical issues such as weighting of genetic versus environmental factors or the impact of environmental factors in relation to critical periods in development. Not only showing the consensus and controversial issues in the various areas, each chapter presents lessons for clinical management in an attempt to link basic research, physiology and pathophysiology with the clinical management of pubertal disorders. Puberty from Bench to Clinic bridges up-to-date concepts from animal and human physiology and pathology towards a better understanding and management of pubertal disorders, making it a unique resource for researchers in the field of development and reproduction, clinical scientists and practitioners in neuro-, pediatric and adolescent endocrinology as well as gynecology.

Dealing with current hot topics, this book aims to provide an update on advances in the treatment of endocrine disorders. The chapters cover innovative therapeutic approaches to type 1 diabetes, such as artificial pancreas and islet transplantation. Additionally, novel pharmacological interventions for patients with obesity and the metabolic syndrome, as well as with adrenal and gonadal disorders are provided. Furthermore, recent developments in growth-promoting therapies, such as the C-type natriuretic peptide analog to treat achondroplasia, as well as antioxidant and gene replacement therapies in patients with adrenoleukodystrophy, are described. Worldwide renowned experts share their experience and cutting edge research in Advanced Therapies in Pediatric Endocrinology and Diabetology, which makes it a useful and interesting resource for every pediatric endocrinologist, not only those active in clinical research, but also those involved in the management of children with endocrine diseases in daily practice.

Considered the definitive source in its field for over 35 years, Endocrinology: Adult and Pediatric, has been thoroughly updated to reflect today's recent advances in adult and pediatric endocrinology. Unique perspectives from a team of trusted, world-renowned experts ensure this medical reference book remains the most highly-regarded text in the field. Make the best clinical decisions with an enhanced emphasis on evidence-based practice and expert opinions on treatment strategies. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. Locate information quickly, while still getting the complete coverage you expect. Now in full color, with special design treatment for at-a-glance pediatric content, helping to distinguish the pediatric content. Expanded coverage for key topics such as pediatric endocrinology and obesity mechanisms and treatment, in addition to today's hot topics in endocrinology, including endocrine disruptors, bariatric surgery, androgen deficiency, genetic causes of obesity, endocrine rhythms, and the use of tyrosine kinase inhibitors in thyroid cancer. New content addressing the latest advances in testosterone and estrogen replacement, as well as the new causes of calcium and phosphate disorders, new molecular causes of endocrine cancers, new genetic causes of reproductive disorders, and more. Updated clinical guidelines for diabetes, lipid disorders, obesity management, osteoporosis, and more, as well as essential treatment updates for the medical management of acromegaly, Cushing's Disease, hypercalcemia, and diabetes mellitus. New Key Points provide snapshots of what to expect in each chapter, or serve as a refresher of what you just read. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.

Bringing together the latest knowledge on the growth and development of children and the most important abnormalities of puberty, this comprehensive text presents the current views on the pathogenesis, diagnostic possibilities and therapeutic options of the main deviations from the normal course of puberty (e.g., precocious and delayed puberty). The chain of physical and hormonal changes in the transitional years is carefully followed, including the regulation of the hypothalamic pulse generator as well as the timing of puberty. Further topics include growth disturbances, adolescent varicocele, adolescent gynecomastia, polycystic ovary syndrome, pubertal acne, and the psychosocial development of adolescents with pubertal abnormalities. Written and edited by internationally noted experts, Puberty will be an excellent resource for pediatricians, endocrinologists, gynecologists, andrologists, urologists, family practitioners, child psychologists and public health specialists – allthose who will be challenged in their everyday practice with the problems of puberty.

La deuxième édition du Livre de l'interne en pédiatrie a été entièrement actualisée pour accompagner au mieux le médecin. Elle comprend les dernières recommandations ainsi que des travaux récents présentant les stratégies diagnostiques ou thérapeutiques. Les auteurs ont choisi les situations les plus fréquentes en privilégiant la pratique : l'examen clinique, les prescriptions d'examens complémentaires et les principaux traitements proposés. L'ensemble des chapitres de ce livre est construit sur un même modèle. La démarche est descriptive, puis analytique. Les points essentiels sont soulignés en début de chapitre, tandis que les tableaux et les arbres décisionnels forment une synthèse visuelle claire. L'ouvrage recouvre l'ensemble des spécialités d'organes concernant l'enfant, depuis la naissance jusqu'au passage de l'adolescence à l'âge adulte. Les 71 chapitres sont répartis en 12 grandes parties : adolescent, cardiologie – hémodynamique, chirurgie, dermatologie, endocrinologie, gastroentérologie, hématologie, maladies infectieuses, néphrologie, neurologie, ORL – ophtalmologie, pneumologie.

Despite the fact that the prevalence of obesity in early childhood has been stable and is no longer increasing in many developed and industrialized countries, the incidence of both obesity and full-blown metabolic syndrome in children and adolescents is still very high. Obesity is a major disease burden in all societies and needs to be prevented early in life. New approaches are eagerly sought and absolutely necessary. This book presents a comprehensive and state-of-the-art summary of current and new knowledge in this critical field. Crucial issues such as nutrition and genetics are described in detail. In addition, new ideas such as e-health and the consequences of urban living conditions are explored. Last but not least, modern treatment concepts and prevention even at an early age are competently discussed. Offering a valuable update on new developments in obesity research and the treatment in children and adolescents, this book is essential reading for all pediatricians and health-care professionals who look after young patients on a regular basis.

Eine adäquate Therapie von Schmerzen bei Kindern, egal welchen Alters, stellt die beste Prävention von chronischen Schmerzen dar. Lesen Sie in dem Standardwerk zum Thema nach, wie Sie gezielt die Therapie gestalten können: - Aktuelle Erkenntnisse zum Schmerzgeschehen bei Kindern, deren Schmerzwahrnehmung und -verarbeitung, - Möglichkeiten zur Schmerzanamnese, medikamentösen Therapie und psychologischen Intervention, - Hinweise zur speziellen Pflege inkl. alternativer Pflegemethoden, - Ambulante und stationäre multimodale Schmerztherapie.Die 5. Auflage erscheint komplett aktualisiert und fachlich erweitert. Neu sind die Themen Gesprächsführung bei chronisch schmerzkranken Kindern und Jugendlichen, Qualitätssicherung in der postoperativen Schmerztherapie, Therapie chronischer Schmerzen bei jungen Erwachsenen und mehr.Plus: Online-Zusatzmaterial u.a. mit zusätzlichen Informationen zur Fort- und Weiterbildung. Wissenschaftlich fundiert und praktisch anwendbar: Zahlreiche Tabellen, Fragebogen und Dokumentationshilfen zu Medikamentendosierungen, Überwachungsbogen, Adressen von Websites und Selbsthilfegruppen. Ein idealer Begleiter für alle Mitglieder im therapeutischen Team: Pädiater, Anästhesisten, Schmerztherapeuten, Physiologen, Psychologen und Kinderkrankenschwestern.

This book focuses on the state of the art in fully grasping precocious puberty and its consequences, incorporating advances in the areas of endocrinology, genetics, imaging and therapeutics to offer an indispensable tool for all physicians interested in the latest advances in this field. The authors present the latest findings on early puberty in girls and boys. The dynamic process of maturation is influenced by many signals and reshapes growing children's role within their environment.Readers will benefit from the educational value and level of depth of the individual chapters; written by respected experts and in a self-contained format, they can also be read separately to address specific interests.

Ten years ago a group of experts assembled in Chicago to develop a consensus on the management of conditions previously described as intersex. The consequences of this consensus have been far reaching, including a change in nomenclature, the development of greater collaboration across geographical boundaries, and a move towards greater involvement of patients and parents. Moreover, an international registry was established, as well as research and clinical networks. This book brings together a thorough overview on all these topics. Furthermore, the major technological advances in diagnostic genetic and biochemical capabilities over the past 10 years are outlined in detail. Offering a comprehensive update on various aspects of disorders of sex development (DSD), this book will be essential reading to all clinicians who are involved in delivering health care to patients with a DSD, as well as scientists involved in biomedical research related to DSD.

New 14th Edition! Keep up with current practice guidelines and policies from the American Academy of Pediatrics with the latest, most up-to-date edition of this clinical reference classic. This evidence-based decision-making tool for managing common pediatric conditions has been revised and updated for 2014, with the latest clinical practice guidelines for more than 30 conditions, plus every AAP policy statement, clinical report, and technical report through December 2013. Updated and expanded for 2014 including:- 3 new pediatric clinical practice guidelines including Management of Newly Diagnosed Type 2 Diabetes Mellitus (T2DM) in Children and Adolescents Diagnosis and Management of Acute Otitis Media Diagnosis and Management of Acute Bacterial Sinusitis in Children Aged 1 to 18 Years- New Periodicity Schedule- Full text of more than 60 new or revised AAP policies- CD-ROM includes the full text of more than 400 AAP clinical practice guidelines, policy statements, clinical reports, and technical reports. - More than 30 clinical practice guidelines including Sleep Apnea guideline, as well as ADHD, bronchiolitis, dysplasia of the hip, gastroenteritis, otitis media, urinary tract infection, and more.- 2014 immunization schedule.

In a single, convenient volume, Pediatric Endocrinology offers complete coverage of all aspects of basic science and clinical practice, ideal for both pediatricians and endocrinologists. Pediatric endocrinology expert Dr. Mark Sperling teams up with world-renowned authors to bring you up to date with the latest key developments in every area of the field, providing invaluable guidance on how your clinical decision making will be affected by today's technological and scientific advances.Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Determine the best possible course for every patient with easy-to-follow algorithms in every clinical chapter. Stay up to date with today's hottest topics, including neonatal diabetes mellitus, Type II childhood diabetes, molecular endocrinology, and genetics. Explore the impact of today's advances and challenges, including explosive growth in molecular biology, sophisticated imaging techniques, and an increase in both pediatric diabetes and obesity. Quickly access the information you need with a new, streamlined organization (Concepts, Endocrine Disorders of the Newborn, Endocrine Disorders of Childhood and Adolescence, and Laboratory Tests and Imaging).

Schmerztherapie bei Kindern erfordert interdisziplinäre Zusammenarbeit und spezielles Fachwissen. Namhafte Experten liefern Ihnen aktuelles Know-how mit gesicherten Therapie-Empfehlungen.Praxis-Plus: Schmerz-Fragebogen, Dosierungsskalen, Überwachungsbogen, wichtige Adressen Neu in der 2. Auflage: Physiologie des nociceptiven Systems, Differentialdiagnose von Schmerzen, Lokalanästhesie, Hautanalgesie, Homöopathie, Schmerztherapie bei Mehrfachbehinderten

Aktuelle Erkenntnisse zum Schmerzgeschehen bei Kindern, deren Schmerzwahrnehmung und -verarbeitung, die Möglichkeiten der Schmerzanamnese sowie der medikamentösen Therapie und psychologischen Intervention sind in diesem Werk übersichtlich zusammengefasst. Der Herausgeber und die Autoren, mit langjähriger Erfahrung im Bereich der Schmerztherapie bei Kindern, stellen die Themen wissenschaftlich, unter den Kriterien'evidence-based-medicine'und gleichzeitig mit starkem Praxisbezug dar.Fragebögen zur Schmerzwahrnehmung, Dokumentationshilfen zu Medikamentendosierungen, Überwachungsbögen sowie Adressen von Websites und Selbsthilfegruppen geben dem Arzt das notwendige Handwerkszeug für eine patientenorientierte Therapie. Das Werk richtet sich in erster Linie an den klinisch tätigen und niedergelassenen Pädiater sowie Krankenpflegepersonal, ist aber auch für Ärzte anderer Fachrichtungen von großer Bedeutung, die Kinder mit Schmerzen zu betreuen haben.

Adolescence is a pivotal period of development with respect to health and illness. It is during adolescence that many positive health behaviors are consolidated and important health risk behaviors are first evident; thus, adolescence is a logical time period for primary prevention. In addition, the predominant causes of morbidity and mortality in adolescence are quite different from those of adults, indicating that early identification and treatment of adolescent health problems must be directed to a unique set of targets in this age group. Moreover, because of the particular developmental issues that characterize adolescence, intervention efforts designed for adults are often inappropriate or ineffective in an adolescent population. Even when chronic illnesses are congenital or begin in childhood, the manner in which the transition from childhood to adolescence to young adulthood is negotiated has important implications for disease outcomes throughout the remainder of the person's life span. Organized in five major sections (General Issues, Developmental Issues, Treatment and Training, Mental Health, and Physical Health) and 44 chapters, Handbook of Adolescent Health Psychology addresses the common and not so common health issues that tend to affect adolescents. Coverage includes: ▪ Context and perspectives in adolescent health psychology ▪ Health literacy, health maintenance, and disease prevention in adolescence ▪ Physical disorders such as asthma, obesity, physical injury, and chronic pain ▪ Psychological disorders such as substance abuse, attention deficit hyperactivity disorder, depression, and eating disorders ▪ Congenital chronic diseases such as type 1 diabetes and spina bifida Handbook of Adolescent Health Psychology is the definitive reference for pediatricians, family physicians, health psychologists, clinical social workers, rehabilitation specialists, and all practitioners and researchers working with adolescents.

Begleitung auf dem letzten Weg:Pädiatrische Palliativversorgung bedeutet, Kinder, Jugendliche und junge Erwachsene mit lebensbedrohlichen oder lebenslimitierenden Erkrankungen begleitend an die Hand zu nehmen und ihre betroffenen Familien zu unterstützen. Körper, Seele und Geist des Kindes benötigen eine aktive und umfassende Betreuung.Wie professionelle Helfer aus dem Palliativteam dem Kind im Angesicht des Todes begegnen können, vermittelt dieses Buch ausführlich und praxisnah, angelehnt an das Curriculum für Palliativmedizin.Die Autoren spannen den Bogen von den strukturellen, organisatorischen und ethischen Grundlagen, den Bedürfnissen von sterbenden Kindern über die praktische Schmerztherapie bis hin zur Situation von Betreuern und Geschwistern sowie Recht und Weiterbildung. Praxisorientierter Schwerpunkt: die Symptomerfassung und Symptomtherapie mit neuen Kapiteln zu Notfällen der Symptomkontrolle und zur palliativen Sedierung. Besonderheiten bei bestimmten Patientengruppen schließen u.a. Aspekte der Versorgung schwerst-mehrfach behinderter Kinder oder krebskranker Kinder ein. Als hilfreiche Stütze in der praktischen Palliativversorgung dienen das neue Medikamentenverzeichnis und ein kompakter Leitfaden zur Optimierung der stationären Palliativversorgung auf Normalstationen.Ein kompetentes Buch für die kompetente Unterstützung Ihrer Patienten.

This textbook provides a comprehensive review of gynecological imaging in infancy, childhood, and adolescence. Experts from the disciplines of pediatric radiology, gynecology, surgery, and endocrinology have come together to produce a textbook that, while written primarily from the perspective of the radiologist, will be of value to all professionals involved in the management of these patients. The normal development of the female reproductive tract is described in detail through embryological development, normal childhood appearances, and puberty. Congenital abnormalities are addressed in chapters reviewing structural abnormalities of the reproductive tract and disorders of sex development. A symptoms-based approach is followed in chapters devoted to the assessment of the patient with gynecological pain and disorders of menstruation. Disorders of the breast and the imaging of patients with gynecological neoplasia are considered in dedicated chapters.

The body of knowledge in most medical specialties is rapidly expanding, making it virtually impossible to follow all advances in clinical and basic sciences that are relevant to a given field. This is particularly true in pediatric endocrinology, at the cross-road of pediatrics, endocrinology, development and genetics. Providing abstracts of articles that report the year's breakthrough developments in the basic sciences and evidence-based new knowledge in clinical research and clinical practice that are relevant to the field, the Yearbook of Pediatric Endocrinology 2012 keeps busy clinicians and scientists, pediatric endocrinologists, and also pediatricians and endocrinologists informed on new advances. Twelve Associate Editors and their co-authors selected from several thousand papers those that brought the most meaningful new information, summarized them and provided comments to put them into perspective. The papers are classified into those that identify new genes involved in diseases, new hormones, concepts revised or re-centered, important observations for clinical practice, large-scale clinical trials, new mechanisms, new paradigms, important review articles, new fears and new hopes. Because the Yearbook is endorsed by the European Society for Paediatric Endocrinology (ESPE), its publication is linked to the annual meeting of the ESPE. The Yearbook of Pediatric Endocrinology 2012 covers the medical and scientific literature from June 2011 through May 2012.

The extended contents of this second edition reflect the growing spectrum of topics in pediatric and adolescent gynecology. Like its predecessor, this book addresses the most common gynecological problems encountered in childhood medicine, including endocrinological and surgical aspects. New chapters place particular emphasis on an update of technological aspects such as ultrasound, molecular genetics, surgery in sex disorders and new problems encountered in reproductive medicine. The book opens with a comprehensive description of the background of infant and adolescent gynecology and diagnostic tools. Several chapters are devoted to the various pathologies encountered in prepubertal and adolescent girls. Contemporary social issues such as sexual abuse, sexually transmitted diseases, contraception for teenagers and teenage pregnancy are also discussed in detail. Presenting a clear plan for clinical management and treatment of frequently encountered problems in prepubertal and adolescent girls, this book should be read by pediatricians, endocrinologists, gynecologists and family practitioners.

Accurately diagnose the entire spectrum of pediatric conditions with the most trusted atlas in the field: Zitelli and Davis'Atlas of Pediatric Physical Diagnosis, 6th Edition. Over 2,500 superb clinical photographs provide unparalleled coverage of important clinical signs and symptoms – from the common (pinkeye) to the rare (Williams syndrome). Trusted by residents and clinicians alike, this updated classic helps you quickly and confidently diagnose any childhood condition you're likely to encounter.Get the comprehensive coverage you need - from pertinent historical factors and examination techniques to visual and diagnostic methods - with over 2,500 practical, clinical photographs to help identify and diagnose hundreds of pediatric disorders. Benefit from authoritative guidance on genetic disorders and dysmorphic conditions, neonatology, developmental-behavioral pediatrics, allergy and immunology, conditions of each body system, child abuse and neglect, infectious disease, surgery, pediatric and adolescent gynecology, orthopedics, and craniofacial syndromes – all enhanced by over 3,400 high-quality images. Prepare for the pediatric boards with one of the best, most widely used review tools available. Access the complete contents and illustrations online at www.expertconsult.com - fully searchable! Get in-depth guidance on your laptop or mobile device with online diagnostic videos of non-seizure neurological symptoms, respiratory disorders, and seizures, plus an infant development assessment tool, a downloadable image gallery (JPEGs or PPTs for easy insertion into academic presentations) and links to PubMed – all online at www.expertconsult.com. Gain an up-to-date understanding of today's hottest topics, including autism spectrum disorders, childhood obesity, inborn errors of metabolism, malformations associated with teratogens, and mitochondrial disorders. Stay current with new chapters and revised coverage of genetics, radiology, development, endocrinology, infectious diseases, cerebral palsy, skeletal syndromes, and child abuse.

Dieses Buch schließt eine Lücke auf dem deutschsprachigen Markt - gibt es doch seit einigen Jahren kein Werk zur Pädiatrischen Endokrinologie mehr. Die'Pädiatrische Endokrinologie und Diabetologie'vereint in einem Band zwei Subdisziplinen, die - trotz aller Eigenständigkeit - alleine schon durch die Weiterbildungsordnung zusammenwachsen. Großen Wert legt das Buch auf Verständlichkeit und Praxistauglichkeit, soll es doch die jungen Assistenzärzte dort abholen wo sie stehen und auf der anderen Seite den Fachärzten ein hilfreicher Begleiter am'Point-of-care'sein. Dargestellt werden alle zum Verständnis notwendigen Grundlagen und natürlich sämtliche Krankheitsbilder. Die Herausgeber haben ein hochkarätiges Autorenteam um sich versammelt und bürgen für Aktualität, Qualität und verläßliche Informationen. Für Fachärzte und angehende Kinderärzte, aber auch Internisten, die Kinder und Jugendlichen in ihren Praxen sehen, geeignet.

The neuroendocrine system plays a pivotal role in the control of growth, puberty, reproduction, and intermediate metabolism. The last decades have witnessed rapid progress in the understanding of the molecular and biochemical mechanisms involved in neuroendocrine function, paralleled by dramatic improvements in imaging techniques. In this volume an international group of basic and clinical investigators presents their latest research on neuroendocrine physiology, advances in the control of the onset of puberty and its disorders, and basic and clinical aspects of the GH/IGF-1 and hypothalamic-pituitary-adrenal axes. An entire section is dedicated to pituitary tumors, including genetics and neuroimaging, and another covers the neuroendocrine control of substrate metabolism, including hypothalamic obesity and anorexia. Pragmatic and topical, this book is a must read for pediatricians, endocrinologists and clinical researchers working in the field of pediatric neuroendocrinology.

Topics in Asthma and Diabetes in Adolescent include: Part I Asthma: Update On Asthma Therapy: Making Sense Of The Guidelines For Adolescents With Asthma, The Management Of Acute Asthma Exacerbations, Asthma In Adolescents Living In The Inner City, Exercise And The Adolescent With Asthma, The Role Of Allergen Exposure And Avoidance In Asthma, Asthma Education: Pitfalls And Solutions. Part II Diabetes:· Type 1 Diabetes Mellitus In Adolescents, Type 2 Diabetes Mellitus In Adolescents, Other Forms of Diabetes in Adolescents, Technological Advancements in Diabetes Care, Psychological Problems In Adolescents With Diabetes.

The neuroendocrine system plays a pivotal role in the control of growth, puberty, reproduction, and intermediate metabolism. The last decades have witnessed rapid progress in the understanding of the molecular and biochemical mechanisms involved in neuroendocrine function, paralleled by dramatic improvements in imaging techniques. In this volume an international group of basic and clinical investigators presents their latest research on neuroendocrine physiology, advances in the control of the onset of puberty and its disorders, and basic and clinical aspects of the GH/IGF-1 and hypothalamic-pituitary-adrenal axes. An entire section is dedicated to pituitary tumors, including genetics and neuroimaging, and another covers the neuroendocrine control of substrate metabolism, including hypothalamic obesity and anorexia. Pragmatic and topical, this book is a must read for pediatricians, endocrinologists and clinical researchers working in the field of pediatric neuroendocrinology.

Continuing advances in the management of childhood malignancies result in a rapidly growing number of childhood cancer survivors. However, many of them experience treatment-induced ‘late effects'including a significant number of endocrine dysfunctions. In this book experts in the field of late effects of childhood cancer treatment offer clinical insight into pertinent issues such as the impact of cancer therapies on growth, puberty and hypothalamic and pituitary function, male and female fertility, obesity, and metabolic and bone problems. Multidisciplinary long-term follow-up of these patients is essential to monitor, treat and prevent morbidity. Therefore this volume is of great interest to pediatric endocrinologists and oncologists, adult and reproductive endocrinologists, primary care practitioners, nurses and nurse practitioners as well as others involved in planning and delivering the holistic care which this increasingly numerous and important group of patients requires.

The body of knowledge in most medical specialties is rapidly expanding, making it virtually impossible to follow all advances in clinical and basic sciences that are relevant to a given field. This is particularly true in pediatric endocrinology, at the cross-road of pediatrics, endocrinology, development and genetics. Providing abstracts of articles that report the year's breakthrough developments in the basic sciences and evidence-based new knowledge in clinical research and clinical practice that are relevant to the field, the ‘Yearbook of Pediatric Endocrinology 2009'keeps busy clinicians and scientists, pediatric endocrinologists, and also pediatricians and endocrinologists informed on new advances. Twelve Associate Editors and their co-authors selected from several thousand papers those that brought the most meaningful new information, summarized them and provided comments to put them into perspective. The papers are classified into those that identify new genes involved in diseases, new hormones, concepts revised or re-centered, important observations for clinical practice, large-scale clinical trials, new mechanisms, new paradigms, important review articles, new fears and new hopes. Because the Yearbook is endorsed by the European Society for Paediatric Endocrinology (ESPE), its publication is linked to the annual meeting of the ESPE. The ‘Yearbook of Pediatric Endocrinology 2009'covers the medical and scientific literature from June 2008 through May 2009.

A Karger'Publishing Highlights 1890–2015'title There is compelling evidence that many of the risks leading to the most frequent chronic diseases in adulthood originate in the earliest stages of life. Adverse environmental conditions in utero and during infancy can lead to negative health effects during the subsequent lifetime of the exposed individual. This book offers precious insights into the latest concepts and results from epidemiologic, clinical and basic studies in this burgeoning area of health care. The developmental origins of various diseases such as diabetes, obesity and cancer are examined, as well as the early programming of reproductive health and different organs. Attention is given to the impact of environmental factors such as nutrition and pollution, and the mediating genetic and epigenetic pathways are reviewed. A crucial point under discussion is the concept of environmental insults adversely affecting not only the exposed persons, but also their descendants. In addition, the economic consequences of a suboptimal start to life and the importance of preventive measures are stressed. This publication is of great value to anyone interested in health care, notably to specialists in obstetrics, pediatrics, internal medicine, obesity, diabetes and heart disease.

Dieses Buch vermittelt einen umfassenden Überblick über das aktuelle Wissen auf dem Gebiet der Neuropsychopharmakologie im Kindes- und Jugendalter. Im ersten Teil werden die Grundlagen der Neuro-Psychopharmakologie dargelegt, um ein tieferes Verständnis der Therapieprinzipien sowie der Besonderheiten der Neuro-Psychopharmakologie bei Kindern und Jugendlichen zu erhalten. Rechtliche und ethische Fragen im Praxisalltag werden eingehend erörtert. Im speziellen Teil werden die verschiedenen Arzneistoffgruppen ausführlich behandelt. Im dritten Teil wird die störungsspezifische und symptomorientierte Medikation praxisorientiert beschrieben und kritisch bewertet, so dass der Arzt über eine klare Handlungsanleitung verfügt. Die 2. Auflage wurde durch Kapitel zu Alkohol- und Drogenmissbrauch erweitert. Dieses Nachschlagewerk besticht durch die komprimierte und einheitliche Darstellung mit vielen zweifarbigen Tabellen, Schemata und Abbildungen. Es wendet sich an Kinder- und Jugendpsychiater und -psychotherapeuten, Pädiater, Allgemeinmediziner, Psychologen, Pflegekräfte und Lehrer.

Behandeln Sie Schmerzen von Kindern angemessen! Die 4. Auflage des Standardwerkes liegt komplett überarbeitet und erweitert für Sie vor: - Aktuelle Erkenntnisse zum Schmerzgeschehen bei Kindern, deren Schmerzwahrnehmung und -verarbeitung, - Möglichkeiten zur Schmerzanamnese, medikamentösen Therapie und psychologischen Intervention, alternative Verfahren, - Hinweise zur speziellen Pflege, incl. alternativer Pflegemethoden, - Eigene Kapitel zu Neugeborenen und Mehrfachbehinderten.Neu in der 4. Auflage: Schmerzepidemiologie, psychologische Invention bei chronischen Schmerzen, Schmerztherapie in der Palliativmedizin, multimodale TherapieprogrammePlus: Exklusiver Zugang zur Homepage www.Vodafone-Stiftungsinstitut.de mit zusätzlichen Informationen, Lehrmaterial, Fallbeispielen und Vorträgen. Wissenschaftlich fundiert und gleichzeitig praktisch anwendbar: Zahlreiche Tabellen, Fragebogen und Dokumentationshilfen zu Medikamentendosierungen, Überwachungsbogen, Adressen von Websites und Selbsthilfegruppen. Ein idealer Begleiter für alle Mitglieder im therapeutischen Team: Pädiater, Anästhesisten, Schmerztherapeuten, Physiologen, Psychologen und Kinderkrankenschwestern.

Completely updated, the new edition of this easy-to-reference text examines the physiological, biochemical, and genetic aspects of pediatric endocrine disorders. Leaders in the field discuss the hottest topics-including genetics, diabetes and obesity-impacting today's endocrine practice, keeping you up to date. A user-friendly organization speeds you to the information you need, and conceptual illustrations and photographs depict the latest advances with consistency and clarity. It's the guidance you need to provide effective, state-of-the-art care for your pediatric and neonatal patients.Examines the physiological, biochemical, and genetic aspects of endocrine disorders all in one convenient reference. Incorporates the importance of molecular biology as it relates to developmental and pediatric endocrinology. Offers expanded coverage of genetics, diabetes and obesity-topics of increasing concern in pediatric endocrinology today.Presents the work of many new contributors for fresh perspectives on the current state of pediatric endocrinology.Provides new tables of normal values and growth charts for monitoring your patients'progress.Concepts, Endocrine Disorders of the Newborn, Endocrine Disorders of Childhood and Adolescence, and Laboratory Tests and Imaging-making the material easy to navigate.

For 20 years, KIGS (Pfizer International Growth Database) has provided an outstanding tool for monitoring the use, efficacy and safety of growth hormone (GH) treatment in children with short stature of varying origin. This volume offers a comprehensive update of the continuing experiences in KIGS and is based on data from more than 50 countries and more than 60,000 patients. International experts analyse in detail the basic auxological characteristics of patients and their response to GH treatment for a broad spectrum of growth disorders. These include idiopathic GH deficiency, organic GH deficiency due to a variety of causes such as congenital malformations and syndromes, genetic disorders or treatment for leukaemia or central nervous system tumours and short stature in children born small for gestational age, specific syndromes and systemic disorders. Each growth disorder is also covered by a review of relevant published data by international experts. KIGS has also established itself as a primary source of information about adverse events during long-term GH treatment in children. The recent analysis of KIGS data has revealed no new adverse drug reactions since the 10-year follow-up. Therefore, treatment with GH seems a low-risk intervention in children and adolescents with various growth disorders. The process of developing disease-specific growth response prediction models has been ongoing in KIGS for many years. The available models are accurate, precise and have a relatively high degree of predictive power, although further predictors of the growth response remain to be identified. The KIGS prediction models can be applied prospectively to new patients, enabling their GH therapy to be better tailored and monitored to achieve optimal growth, safety and cost outcomes. The future of KIGS within the era of evidence-based medicine will continue to depend upon the quality of the data reported. Therefore, the commitment of participating physicians will continue to be a decisive element. The ongoing recognition of the importance of valid safety and efficacy information in the practice of paediatric endocrinology is exemplified by this valuable international collaboration of clinicians and the pharmaceutical community.

Your best source for guidance on the visual diagnosis of pediatric disorders now comes to you in print and online! More than 3,400 hundred illustrations-3,000 in full color-capture the full range of gross anatomic signs as well as laboratory and radiologic findings for hundreds of pediatric disorders.Addresses the entire spectrum of pediatric conditions-from pertinent historical factors and examination techniques to visual and diagnostic methods-providing you with comprehensive coverage for your toughest diagnostic challenges.Features more than 3,400 practical, clinical photographs to help you identify and diagnose hundreds of pediatric disorders.Features new, comprehensive coverage of malnutrition, obesity, and trauma to help you identify a wide range of conditions.Includes expanded information on child abuse and neglect so you can better recognize and manage the signs and symptoms of this sensitive condition.Presents new coverage in the Genetic Disorders and Dysmorphic Conditions chapter to assist you in diagnosing metabolic diseases more accurately.Offers online access to the entire searchable contents of the book for quick answers to clinical questions.Provides online downloadable images from the book that allow you to create your own electronic presentations.