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This volume provides the most updated knowledge on the advancement of molecular pathogenesis, molecular diagnosis, and therapy development for hepatocellular carcinoma (HCC). Topics covered include the etiology and pathogenesis of HCC, recent advances in HCC genomics, biomarker discovery and validation in HCC diagnosis, the role of liver biopsy in HCC early diagnosis, and the future prospects of surgical approaches and targeted therapy for HCC. In addition to reviewing the current available knowledge, the book also discusses the future development of a precision and personalized medicine approach for HCC.Written by experts in the field, Precision Molecular Pathology of Liver Cancer is a concise yet comprehensive resource for practitioners who treat patients with hepatocellular carcinoma.

Aktuelles klinisches Wissen zu allen hepatobiliären Erkrankungen. Und das in gut lesbarer, didaktisch durchdachter Aufbereitung. Was wünschen Sie sich mehr bei einem Hepatologiebuch? Als Hepatologie-Neuling wird das Buch Ihre Freude an dem Fach wecken und gleichzeitig Ihr Verständnis für die klinische Hepatologie erleichtern. Lernen macht Spaß, wenn morphologische und pathophysiologische Grundlagen so anschaulich dargestellt werden. Doch auch der gestandene Hepatologe findet hier neues Wissen, das er gleich in die Praxis umsetzen kann. Durch die klare Gliederung finden Sie auch unter Zeitdruck schnell Informationen zu einer gerade brennenden Fragestellung. Und damit erfüllt das Buch sein eigentliches Ziel: die qualifizierte ärztliche Versorgung von Patienten mit hepatobiliären Erkrankungen.

Cellular and Molecular Pathology of the Liver is extensive, complex and ranges from the understanding the basic molecular mechanisms that dictate everything from liver homeostasis to liver disease. Molecular Pathology of the liver is complicated due to some of the important functions inherent and unique to the Liver, including its innate ability to regenerate and the multitude of functions it plays for the wellbeing of an organism. With all this in mind, Molecular Pathology of Liver Diseases is organized in different sections, which will coherently and cohesively present the molecular basis of hepatic physiology and pathology. The first two sections are key to understanding the liver anatomy and physiology at a cellular level and go on to define the molecular mechanics in various liver cell types. These sections also cover the existing paradigms in liver development, regeneration and growth. The next section is key to understanding the Molecular Pathology unique to liver diseases and associated phenotypes. The final sections are geared towards the existing knowledge of the molecular basis of many common and uncommon liver diseases in both neoplastic and non-neoplastic areas including pathologies associated with intra-hepatic and extra-hepatic biliary tree. Thus, this textbook is a one-stop reference for comprehending the molecular mechanisms of hepatic pathobiology. It is clearly unique in its format, readability and information and thus will be an asset to many in the field of Pathology and other disciplines.

Clinical Hepatology – Principles and Practice of Hepatobiliary Diseases provides clear and comprehensive coverage of the etiology, mechanisms of disease, diagnosis, and practical management of the entire spectrum of liver and biliary disorders. It also affords an excellent, evidence-based review of the rapidly expanding field of hepatobiliary diseases.