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This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners and trainees at all levels of experience and training. Covering all aspects of cytology, including gynecologic, nongynecologic exfoliative, fine-needle aspiration, and imaging, it incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Cytopathology is a visually stunning, one-stop resource for every practicing pathologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource. Covers all areas of cytopathology, including clinical, radiologic, and immunohistochemical as well as cytopathologic features and molecular correlates where applicable Contains new chapters on ancillary molecular tests specific to thyroid, prognostic/therapy-related immunomarkers in cell blocks, and small biopsies Provides new immunohistochemical and molecular coverage, including new immunostains and genomic targets Incorporates new reporting terminology (such as serous fluid and effusions) and updates to existing reporting terminologies Reflects the expanded use of fine-needle aspiration for small biopsies (FNA-B) with many more images added and updated throughout Keeps you up-to-date with current and emerging reporting systems on pancreaticobiliary, salivary, breast, and soft tissue cytology Features more than 3,000 print and online images, including carefully annotated histology and gross pathology photos, full-color illustrations, clinical photographs, and radiologic images to help practicing and in-training pathologists reach a confident diagnosis Includes new videos on such topics as the cytoprepratory process, cell transfer cell block and smears, collodion bag cell block, and more Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert cytopathology reference at the point of care

In the third edition of the book, The digital pathology, whole slide scanning, and artificial neural network are described in details in Chapter 19. Furthermore, there are several significant changes in different techniques, such as the polymerase chain reaction and next-generation sequencing, immunocytochemistry, and flow cytometry. In addition, the molecular pathology and immunocytochemistry of various tumors are highlighted in each chapter. Updated classification of the World Health Organization and International Academy of Cytologists in the urinary cytology, lung, breast, salivary gland, and lymph node have also been discussed.

This book provides a comprehensive, practical, and state-of-the art review addressing the major issues and challenges in cytopathology practice using a question and answer format. Making an accurate diagnosis, especially on a limited cytology sample obtained by minimally invasive procedures, is often challenging, yet crucial to patient care. Using the most current and evidence-based approaches, this book: 1) focuses on frequently asked questions in day-to-day practice of cytopathology as well as surgical pathology; 2) provides quick, accurate, and useful answers; 3) emphasizes the importance of clinical, radiological, and cytological correlation, as well as cyto-histological correlation; and 4) delineates how to judiciously use immunohistochemistry, molecular tests, flow cytometry, cytogenetics, and other established ancillary studies including next generation sequencing and computer-assisted diagnostics. Chapters are written by experts in their fields and provide the most up-to-date information in the field of cytopathology. Practical Cytopathology: Frequently Asked Questions serves as a practical resource and guide to relevant references for trainees, cytotechnologists, and cytopathologists at various skill levels.

This richly illustrated book will help presurgically diagnose pediatric/young adult tumors. The content is divided into two parts. The first part shows step-by-step how to perform a small volume specimen such as fine needle aspiration/core needle biopsy and how to correlate the morphology with the clinical, radiological, and/or molecular information. In turn, the second part presents a comprehensive overview of the various tumor entities. The content represents diagnostic modalities from the major diagnostic centers worldwide, and is supplemented by the authors` 25 years of experience in diagnosing pediatric tumors. This book will successfully guide practitioners, researchers and oncology pediatricians through the process of sample harvesting and diagnosing. Pediatric tumors represent a large variety of lesions including pseudotumors of inflammatory and non-inflammatory origin, various types of lympadenopathy, benign lesions, specific sarcomas, and blastemal malignancies. These age-specific and histotype-specific tumors of various origin, evolution and prognosis are often characteristic in morphological and molecular levels, making their diagnosis highly specialized.

•This new edition has been fully revised to provide trainees and clinicians with the latest advances in the field of cytology. •Divided into four sections, viz. general cytology, clinical cytology (exfoliative cytology and fine needle aspiration cytology), and laboratory techniques in cytology. •Includes two new chapters on round cell tumours and infections. •Contains all the recent information in the field of cytology including most recent classifications, molecular genetics, laboratory techniques, etc. •Contains large number of tables, boxes, line arts and microphotographs in every chapter. •Important information is highlighted in small boxes. •Incorporates multiple choice questions along with microphotographs with each chapter for self-assessment. •Both a theoretical and practical resource for the trainees and the practicing cytopathologists.

​The Essentials in Cytopathology book series fulfills the need for an easy-to-use and authoritative synopsis of site specific topics in cytopathology. These guide books fit into the lab coat pocket and are ideal for portability and quick reference. Each volume is heavily illustrated with a full color art program, while the text follows a user-friendly outline format. Central Nervous System Intraoperative Cytopathology covers the full spectrum of benign and malignant conditions of the CNS with emphasis on common disorders. The volume is heavily illustrated and contains useful algorithms that guide the reader through the differential diagnosis of common and uncommon entities encountered in the field of intraoperative neuro-cytopathology. This book will be a valuable quick reference for pathologists, cytopathologists, and fellows and trainees dealing with this exigent field.Since the successful First Edition, the advances in radiological, clinical, morphological, and molecular aspects of CNS diseases, as well as the increasing options for different treatments modalities require updating of textbooks and revision of diagnostic algorithms. To reach this aim, Central Nervous System Intraoperative Cytopathology, Second Edition features the incorporation of 3 new chapters, 2 appendices, and all new full-color images in the text with updates of new diagnostic information according to 2016 WHO classification of CNS tumors. This fully updated edition also includes expanded clinic-radiological approach, recent biomarkers, and cytological features of new WHO entities. In summary, the text has been extensively revised and largely rewritten to offer the practicing pathologist a concise summary of the critical information needed to recognize and interpret the current exigent field of intraoperative neurocytopathology.

Cytology is a unique subspecialty in anatomic pathology, and plays a critical role in the diagnosis of a variety of benign and malignant lesions by using minimally invasive procedures, such as fine needle aspiration, brushing, washing and lavage. Cytology not only provides an accurate diagnosis of the lesion based on the cytomorphological evaluation at cellular level, but also provides material for molecular characterization of a tumor for targeted therapy. In the era of personalized medicine, cytology has continued to grow and evolve as an important diagnostic tool. For example, some types of procedures are routinely used, diagnostic criteria have become more refined, and certain terminology has been changed based on current WHO classifications. Therefore, it is necessary to update our knowledge and terminology in cytology. In this volume, we have retained the quality and the clarity of the series, and like the other volumes, this volume aims to be concise and comprehensive yet clinically relevant to daily practice. Although this volume is written by multiple authors, all chapters follow a similar format: brief introduction of the specific organ/system (including types of specimens and techniques to obtain samples), description of normal findings, and a practice approach to diagnose benign and malignant lesions. In each chapter, the key cytomorphological feature and main differential diagnoses of the lesion are summarized in a concise table. Images in each chapter are instructive and clearly represent findings. Where necessary, we have also illustrated the important ancillary tests, such as flow cytometry, immunohistochemistry and molecular analysis, which are crucial for an accurate diagnosis and targeted therapy. The updated knowledge, including key cytomorphological features, current terminology and molecular diagnostic tests, is the highlight of this volume.

This text presents serious challenges for trainees, clinicians, and practicing pathologists and cytopathologists due to the wide spectrum of diagnoses that may be seen in children and the lack of familiarity with these entities. This reference book has been designed as a practical, high-yield review of pediatric cytopathology. Key findings are highlighted and up-to-date information is provided on the diagnosis of pediatric lesions by cytology, with extensive guidance on differential diagnosis. The book includes tables and full-color images of the cytomorphology and ancillary studies, as well as pertinent histological correlation and guidance on technical issues. Pediatric Cytopathology: A Practical Guide will be an essential reference for anyone interested in the cytomorphological findings in childhood diseases.

Liquid-based cytology preparations are currently the standard of care for gynecological cytology, and are being increasingly used for non-gynecological cytology. Diagnostic Liquid-Based Cytology serves as a handy guide to diagnostic cytopathology on liquid-based preparations. The authors, renowned experts in the field, provide clear, concise, and practical diagnostic guidance.This handbook equips you to achieve accurate diagnosis of most commonly and uncommonly encountered diseases in exfoliative and aspirated tissue samples from various sites. The key cytopathological features of various diseases are described. The book is lavishly illustrated with dozens of color images that depict the full range of common and rare conditions.Diagnostic Liquid-Based Cytology offers highly practical guidance and information needed to solve common diagnostic challenges in liquid-based cytology preparations. Appropriate histopathological correlations and a consideration of the possible differential diagnosis accompany the cytological findings. The book is an excellent resource not only for practicing pathologists as well as for pathologists-in-training, and will be the perfect practical resource for daily reference in the cytopathology laboratory.

This book reviews the current applications of molecular tools in cytopathology and provides a concise handbook for those who provide care in this era of personalized medicine. Specifically, the text provides a comprehensive and concise review of the emerging molecular tests available clinically in different subspecialities of diagnostic pathology. It reviews the current data of molecular testing already applied in cytopathology, discusses some of the biomarkers with potential utility in cytopathology in the near future and reviews the technical challenges in applying and validating molecular tools in liquid-based cytologic materials. Molecular Cytopathology will serve as a valuable resource for cytopathologists, cytotechnologists, pathology trainees, and clinicians with an interest in molecular applications in cytopathology.

This book provides cytopathologists a succinct but comprehensive reference covering common diagnostic dilemmas caused by normal, iatrogenic, inflammatory and reactive/reparative changes in cytology samples. This book will provide immediate access to these confounders, clearly illustrating key features and detailing the pitfalls these cells engender in all cytologically accessible body sites. The text is organized in chapters corresponding to cytologically accessible body sites/organ systems. Each chapter's discussions are further organized by general categories of confounders (i.e., normal contaminants, inflammatory, infectious and iatrogenic), with special attention to site specific confounders. Pitfalls in Diagnostic Cytopathology With Key Differentiating Cytologic Features will be of great value to practicing pathologists, pathology residents, cytopathology fellows, cytotechnology technologists and students.

This book offers clear, up-to-date guidance on how to report cytologic findings in cervical, vaginal and anal samples in accordance with the 2014 Bethesda System Update. The new edition has been expanded and revised to take into account the advances and experience of the past decade. A new chapter has been added, the terminology and text have been updated, and various terminological and morphologic questions have been clarified. In addition, new images are included that reflect the experience gained with liquid-based cytology since the publication of the last edition in 2004. Among more than 300 images, some represent classic examples of an entity while others illustrate interpretative dilemmas, borderline cytomorphologic features or mimics of epithelial abnormalities. The Bethesda System for Reporting Cervical Cytology, with its user-friendly format, is a “must have” for pathologists, cytopathologists, pathology residents, cytotechnologists, and clinicians.