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​Nutraceuticals are defined as any food bioactive compounds or supplements which provide health and medicinal benefits, usually in the prevention of disease and sometimes playing a role in their treatment as well. Nutraceuticals are a combination of a variety of nutrients ranging from vitamins and minerals to certain amino acids. Nutrients are an essential part of the diet and serve a variety of roles in human physiology through various enzymes which govern biocatalysis in various metabolic pathways including tissue and DNA repair and body defense and immunity. Nutrients that are routinely prescribed as dietary supplements include multivitamins, minerals and certain specific amino acids. Nutraceuticals not only serve a pivotal role in tissue repair and body defense mechanism but also play a crucial role in various signal transduction and metabolic pathways. The deficiency of any crucial nutrient can negatively affect metabolic and transduction pathways which can lead toa variety of diseases and disorders. The preventive use of nutraceuticals is a promising new trend for a variety of diseases and disorders. Nutraceuticals: A New Millennium Approach for Preventive Medicine focuses on the preventive use of nutraceuticals to avoid various diseases and disorders. The chapters cover nutrients and human physiology, metabolism and xenobiotics, plus their use in the prevention and treatment of a wide range of diseases and disorders from cancer to cardiovascular disorders to diabetes and renal diseases. Further chapters study the role nutraceuticals play in the treatment of depression and mental illnesses, neurogenerative diseases and autoimmune diseases. The relationship between nutrients and suboptimal health is explored as are links between nutrition and infertility. As these food supplements continue to gain in popularity with consumers, it is increasingly important to understand their benefits and limitations in the prevention and treatment of various diseases and disorders, and this book offers a fully up-to-date snapshot for researchers.

Nutrition and Osteoporosis: Seeing Through a Glass, Darkly (1 Cor. 13:12) This volume of Advances in Nutritional Research deals with the present state of knowledge relative to the role of nutrition in the etiology of osteoporosis, one of the most serious degenerative diseases in the aging population. As a back­ drop for subsequent chapters on specific nutrients, Chapter 1 provides a com­ prehensive account of the gain and loss of bone throughout the life cycle, with emphasis on the architectural changes in later life that predispose to osteoporotic bone fractures. Chapter 2 documents the occurrence of aging bone loss through­ out human archeological history and Chapter 3 extends this documentation to all non-human vertebrate species so far examined, including primates living in the wild. It is apparent that a progressive loss of bone tissue is a normal accompaniment of aging among higher vertebrates. Whether it is a cause of bone fractures in animals, as it is in humans, is still unknown. It has also been established that there are significant differences in the frequency of osteoporotic fractures among human families, ethnic groups, national populations and diet cultures. Numerous studies have been carried out in an effort to explain these differences, and many of these deal with the possible effect of nutrition. Protracted controversies over the role of nutrition in the etiology of osteoporosis are reflected in the contents of several of the ensuing chapters.

Volume 8 of Advances in Nutritional Research deals with several topics of prime current interest in nutritional research, including the role of nutrition in hypertension, in the infections associated with protein-energy malnu­ trition, and in pathological conditions associated with the generation of oxygen radicals in the tissues, as well as with topics of ongoing interest. Recent research indicates that reduction of obesity, of alcohol intake, and of sodium intake by salt-sensitive individuals, are the most effective non­ pharmacological means of reducing high blood pressure. A new approach to therapy for infections caused by protein-energy malnutrition, based on restoration of immunocompetence by administration of thyroid and anti­ glucocorticoid hormones, is presented. Current research into the role of nutrition in modulating tissue damage caused by oxygen radicals generated in various pathologies is reviewed. Two· chapters deal with perinatal nutrition, one with the transfer of nutrients across the placenta and the other with the energy requirements of term and preterm infants. Another dicusses methods of assessing the nutritional status of hospitalized patients. vii Contents Chapter 1. The Transfer of Nutrients across the Perfused Human Placenta.................................... Joseph Dands 1. Introduction................................. 1 2. Comments on Comparative Placentology...........•.. 1. 3. The Perfusion Technique..................... 3.... 4. Review of Transfer Experiments.................... 3 4.1. Transfer of Glutamic Acid.................... 3 4.2. Transfer of Riboflavin................ •... 6... 5. Potentials and Umltations.................... 9....References........................... 10......

Das Heft umfasst folgende Berichte: Gesundheitliche Bewertung von pharmakologisch wirksamen Substanzen; Lebensmittelsicherheit von Rückständen von Tierarzneimitteln; Target Animal Safety for Veterinary Pharmaceutical Products (VICH GL 43); Beurteilung und Überwachung der Resistenzsituation bei und nach der Zulassung von Tierarzneimitteln.

Das Heft umfasst folgende Berichte: Gesundheitliche Bewertung von pharmakologisch wirksamen Substanzen; Lebensmittelsicherheit von Rückständen von Tierarzneimitteln; Target Animal Safety for Veterinary Pharmaceutical Products (VICH GL 43); Beurteilung und Überwachung der Resistenzsituation bei und nach der Zulassung von Tierarzneimitteln.

For more than two decades, this work has remained the leading advanced textbook and easy-to-use reference on food chemistry and technology. Its fourth edition has been extensively re-written and enlarged, now also covering topics such as BSE detection or acrylamide. Food allergies, alcoholic drinks, or phystosterols are now treated more extensively. Proven features of the prior editions are maintained: Contains more than 600 tables, almost 500 figures, and about 1100 structural formulae of food components - Logically organized according to food constituents and commodities - Comprehensive subject index. These features provide students and researchers in food science, food technology, agricultural chemistry and nutrition with in-depth insight into food chemistry and technology. They also make the book a valuable on-the-job reference for chemists, food chemists, food technologists, engineers, biochemists, nutritionists, and analytical chemists in food and agricultural research, food industry, nutrition, food control, and service laboratories. From reviews of the first edition'Few books on food chemistry treat the subject as exhaustively…researchers will find it to be a useful source of information. It is easy to read and the material is systematically presented.'JACS