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Using a practical, easy-to-reference signs and symptoms approach, Fenichel's Clinical Pediatric Neurology, 9th Edition, provides a solid foundation in the diagnosis and management of primary neurologic disorders of childhood while bringing you fully up to date with developments in the field. It offers step-by-step, authoritative guidance that considers each presenting symptom in terms of differential diagnosis and treatment, reflecting real-life patient evaluation and management. Perfect for board exam preparation, office use, or residency reference, this well-organized, revised edition is an ideal introduction to this complex and fast-changing field. - Defines age at onset, course of illness, clinical features, and treatment options for each neurological disease, all logically organized by neurological signs and symptoms in a highly templated format. - Brings you up to date with every aspect of the field, with integrated content on new medications, new topics such as neurological complications of COVID in children, and a new chapter on behavioral neurology. - Includes comprehensive coverage of genetics in relation to epilepsy, autism, and many neurometabolic disorders, with up-to-date coverage of genetic testing, diagnosis, and pharmacogenomics. - Features weighted differential diagnosis tables and treatment algorithms that help you quickly identify the more common and most treatable neurological disorders, as well as evaluate and manage the most difficult neurodegenerative disorders, including those caused by inborn errors of metabolism. - Provides helpful boxes that synthesize symptoms and foundational points, an increased number of imaging examples throughout, and more than 300 illustrations, tables, and charts that support and clarify the text. - Shares the knowledge and experience of clinical neurologist and epileptologist, Dr. Kaitlin C. James, and Dr. J. Eric Piña-Garza, a longtime associate and protégé of Dr. Gerald Fenichel.

Die 3. Auflage des Handbuchs bietet Klinikern, Laboratoriumsmedizinern, experimentell Forschenden sowie allen, die sich für den Liquor cerebrospinalis interessieren, in der täglichen Praxis eine schnelle und fundierte Orientierung über den aktuellen Wissensstand der Liquordiagnostik. Methoden und Indikationsstellungen zur Gewinnung des Liquor cerebrospinalis sowie die Analyseverfahren, Messparameter und Befundkonstellationen werden im Licht der neuesten Erkenntnisse ausführlich dargestellt. Das Buch ermöglicht eine umfassende Einsicht in methodische und interpretatorische Aspekte aller klinisch bedeutsamen Liquorparameter sowie in den Stellenwert der Liquordiagnostik heute. Neben den aktuellen Entwicklungen in Immunologie, Molekularbiologie und Proteinanalytik sowie der Standardisierung und Qualitätssicherung ist in der Neuauflage erstmals ein 50-seitiger Zytologieatlas mit exemplarischen Fallbeschreibungen Teil dieses Lehrbuches, welcher sich konzeptionell am stufenweisen Erfassen eines zytologischen Präparats orientiert und daher auch besonders für Einsteiger in die Liquorzytologie geeignet ist. Mit Unterstützung der Deutschen Gesellschaft für Liquordiagnostik und Klinische Neurochemie e.V. (DGLN).

This book focuses on the clinical and preclinical research on traumatic brain injuries where age at time of injury (young versus aged) reveals both parallel and divergent findings at the molecular, cellular, and behavioral levels with insights into alterations in brain structure and function and the implications for recovery. The authors address the hurdles that have been overcome, consider new directions inspired by the most recent research, and the value of data sharing and evidenced based-practice. Traumatic Brain Injuries: Tackling the Unique Terrain of the Injured Young and Aged Brain explores the challenges imposed by an injury that not only causes tissue damage but disrupts brain development and may incite pathological events in the aging brain. With the proliferation of the research literature in traumatic brain injuries, this is the time for a book that surveys the landscape and assesses where the field is headed and what is needed moving forward.

While the first edition of this book provided a succinct introduction to pediatric neuro-oncology, biological knowledge of childhood CNS tumors has “exploded” over the past few years and a new edition of this textbook is needed to keep it up-to-date. This updated edition will include chapters on cancer predisposition in children with brain tumors, gliomas, embryonal brain tumors, ependymoma, CNS-GCT, targeted therapies in pediatric brain tumors, and long-term sequelae. New developments covered include the following: - Techniques like DNA methylation have improved the diagnostic process, and have led to an integrated diagnosis of histology, ICH and methylation. - Tumor pathways have been detected, which defines more subgroups within a tumor entity, and results in more individualized treatment for the patient. - Therapeutic options outside the standard combination of surgery, chemotherapy, and radiation have either been implemented within the last years, or are currently under consideration. This book will be aimed at pediatric oncologists and neurooncologists, neurosurgeons, radiation oncologists. Chapters detailing quality of life and supportive care will make this 2nd edition a useful resource for nurses, social workers, physiotherapists, and occupational therapists alike.

This extensively updated edition provides a comprehensive review of intensive care for neurologically injured patients from the emergency room and ICU through the operating room and post-surgical period in two comprehensive volumes. The Editors of this first volume present a comprehensive textbook that incorporates best practice/evidence-based medicine and performance improvement, while it champions the three characteristics needed in our neuro–ICUs: patient and family centered high-quality care, education, and discovery. This volume concentrates on neuroanatomy, diagnostic assessment and disease management, examining the neurological problems most frequently seen in intensive care, and describes the various types of neurosurgery and critical features of the management of patients. General issues are discussed across the textbook, such as cardiac care, fluids and electrolytes, nutrition, and monitoring as well as more specific conditions and complications including elevated intracranial pressure, seizures, and altered mental states. Listening to an injured brain is not easy. It takes knowledge, dedication, and understanding of the critically ill patient and their family. Textbook of Neurointensive Care Volume 1: Neuroanatomy, Diagnostic Assessment, Disease Management provides the reader with a detailed resource for studying this most complex area of medicine. It is thus essential reading for all trainees and professionals in critical care, neurosurgery, anesthesia and neurology.

This extensively updated edition provides a comprehensive review of intensive care for neurologically injured patients from the emergency room and ICU through the operating room and post-surgical period in two comprehensive volumes. The Editors of this second volume present a comprehensive textbook that incorporates best practice/evidence-based medicine and performance improvement, while it champions the three characteristics needed in our neuro–ICUs: patient and family centered high-quality care, education, and discovery. This volume concentrates on perioperative management, monitoring and pharmacotherapy, examining the neurological problems most frequently seen in intensive care, and describes the various types of neurosurgery and critical features of the management of patients. General issues are discussed across the textbook, such as cardiac care, fluids and electrolytes, nutrition, and monitoring as well as more specific conditions and complications including elevated intracranial pressure, seizures, and altered mental states. Listening to an injured brain is not easy. It takes knowledge, dedication, and understanding of the critically ill patient and their family. Textbook of Neurointensive Care Volume 2: Perioperative Management, Monitoring, Pharmacotherapy provides the reader with a detailed resource for studying this most complex area of medicine. It is thus essential reading for all trainees and professionals in critical care, neurosurgery, anesthesia and neurology.

Greenfield's is the world's leading neuropathology reference. It provides a comprehensive account of the pathological findings in neurological disease, their biological basis, and their clinical manifestations. The two volume work provides a remarkable text which is clear, comprehensive and precise with exceptional illustrations. The tenth edition features fully updated sections covering CNS tumours, neurodegeneration, skeletal muscle, epilepsy, paediatric and forensic neuropathology.Expert coverage from an international team of Editors and contributors ensures authoritative and up to date content. The two volume set includes a downloadable and easily used e-version. This is a tried and tested reference for scientists, clinicians, researchers, and students who wish to learn more about neurological disease.

Electroencephalography (EEG) is one of the oldest neurophysiological techniques used to evaluate brain activity and is a cornerstone of technical diagnostics in neurology. The technical advancement of electroencephalography in the last few decades, however, asks for a new approach to EEG reading. This textbook and atlas provides a systematic approach to normal and abnormal EEG patterns, serving as an instructional guide for the beginner in EEG and an essential reference for the experienced EEG reader. Containing about 400 figures illustrating typical EEG patterns which are also available online in reformatted referential and bipolar montages, this book covers how electrical waves are generated into the brain, the equipment required to record electrical brain waves (including the set-up of EEG machines, electrodes, and procedures), biological and non-biological disturbances called artifacts in EEG recordings, and differentiation of normal and abnormal patterns in EEG. The reader will be introduced to a systematic analysis of EEG interpretation by defining the characteristics of the EEG patterns (polarity, localization, frequency, modulation etc.) and their clinical meaning, making this an essential text that should be on the bookshelf of every medical professional using EEG.

The definitive text on the diagnosis and treatment of sports-related neurological injuriesAlthough musculoskeletal injuries are by far the most common injuries seen in sports, neurological injuries are often the most serious and potentially devastating. The Brain, Spine and Nerves in Sports is a comprehensive textbook edited by neurosurgeons Nicholas Theodore and Russell R. Lonser, internationally renowned experts in sports-related brain and spine trauma. The book covers intricacies associated with the diagnosis and treatment of sports-related neurological injuries, with firsthand, collaborative insights from a who's who of multidisciplinary neurological experts in sports injury medicine.The book is organized into four sections and 40 thoughtfully curated chapters covering diagnosis, surgical and nonsurgical approaches, and management of traumatic brain injuries, concussions, spinal cord injuries, and peripheral nerve injuries. The final chapter focuses on leveraging concussion data to improve the safety of American football. Each chapter blends theoretical knowledge, evidence-based practices, case studies, and practical insights derived from the authors'extensive clinical experience.Key FeaturesContributions and pearls from leading authorities in the fields of neurosurgery, spine surgery, sports medicine, and rehabilitationThe latest advancements, techniques, and best practices for managing neurological conditions in athletes, presented in a succinct, easy-to-digest format, with short videosDetailed, critical overviews of sports-related neurological injuries in American football, soccer, cycling, baseball, skiing, combat sports, ice hockey, rugby, and moreA wealth of tables and assessment tools to enhance management of challenging, often time-sensitive situations, including complex return-to-play issuesThis definitive textbook will help neurosurgeons, orthopedic surgeons, neurologists, trainers, sports medicine physicians, and pain management physicians optimize patient outcomes, enhance performance, and promote the overall well-being of athletes at all levels of competition.

This practical, case-based book offers an approach to diagnosis and treatment of movement disorders in the outpatient setting. The major hypokinetic and hyperkinetic disorders are considered in turn, with more than 1,000 videos illustrating the role of phenomenology in the diagnosis and treatment of these conditions. Discussion of the role of ancillary testing (imaging, genetic testing) and treatment options with medications, botulinum toxin injections, and surgical intervention are woven in to the discussion of cases throughout the book. Special attention is directed to pitfalls and perils of office-based practice. This volume will be of interest to movement disorders neurologists and trainees, general neurologists, neurology residents, and any healthcare professional with an interest in exploring the application of the many treatments that have transformed movement disorders into a therapeutic field. Rather than a textbook of movement disorders, thisvolume will help the practicing clinician in guiding the thought process for evaluation and management of patients in the clinic.

Ce volume consacré aux neuropathies périphériques aborde l'organisation et les fonctions du système nerveux périphérique, sa physiopathologie et la classification de ses atteintes. Une équipe de 28 auteurs francophones, reconnus aux niveaux national et international, apportent par leur expérience les données nécessaires à la révision et à la compréhension de l'anatomie, de l'histologie et de la physiologie. Richement illustrés de schémas et figures, d'un résumé didactique, les différents chapitres décrivent :• les apports attendus des explorations fonctionnelles, de l'imagerie, des biopsies de nerf et peau, des analyses génétiques ;• les clés utiles pour une orientation étiologique et à une prise en charge dans les centres de référence ;• l'ensemble des neuropathies focales et générales, en fonction de leurs différentes expressions cliniques et électrophysiologiques, de leurs causes et de leurs prises en charge ;• les échelles et scores de fonction qui permettent la quantification et le suivi clinique. Cet ouvrage destiné aux neurologues et internistes désireux de consulter une référence unique par son abord didactique, scientifique et clinique des maladies du système nerveux périphérique, est complété d'un volume consacré à l'étiologie des neuropathies périphériques spécifiques de causes définies.

This collection of epilepsy surgical cases illustrates patients with straightforward and challenging pharmacoresistant epilepsy. These cases convey the advancements, investigative strategies, past and modern surgical tools, and sophisticated state-of-the-art of epilepsy surgery and its disciplines. This textbook is organized into four major sections that parallel the contemporary FDA-approved and clinically applicable approaches: resective surgery, disconnection procedures, laser therapy, and neuromodulation. The chapters provide a case-based, interactive, and multidisciplinary integrative approach to pre-operative evaluation, data analysis, and surgical decision-making. In addition, we present alternative approaches to certain diagnostic tools, decision-making strategies, and surgical interventions.This textbook will provide trainees and clinicians with an exhaustive understanding of epilepsy surgery. Moreover, it will be an invaluable resource for preparation for the epilepsy board examination

This textbook presents real-world cases and discussions that introduce the various psychiatric syndromes found in the aging population before delving into the core concepts covered by geriatric psychiatry curricula. The text follows each case study with the vital information necessary for physicians in training, including key features of each disorder and its presentation, practical guidelines for diagnosis and treatment, clinical pearls, and other devices that are essential to trainees in geriatric psychiatry. With the latest DSM-5-TR guidelines and with rich learning tools that include key points, review questions, tables, and illustrations, this text is the only resource that is specifically designed to train both US and Canadian candidates for specialty and subspecialty certification or recertification in geriatric psychiatry. It will also appeal to audiences worldwide as a state-of-the-art resource for practice guidance. The text meets the needs of the future head on with its straightforward coverage of the most frequently encountered challenges, including neuropsychiatric syndromes, psychopharmacology, elder care and the law, substance use disorders, psychiatric comorbidities in systemic medical illness, consultation-liaison psychiatry, palliative care, climate change and health, and equity/diversity/inclusion matters in the care of older adults. Written by experts in the field, Geriatric Psychiatry: A Case-Based Textbook, 2nd edition will be the ultimate resource for graduate and undergraduate medical students and certificate candidates providing mental health care for aging adults, including psychiatrists, psychologists, geriatricians, primary care and family practice doctors, neurologists, social workers, nurses, and others.

A Video Atlas of Neuromuscular Disorders is the essential reference on adult neuromuscular disorders and their diagnosis and treatment. Written with the busy Fellow, Resident, and clinician in mind, the work utilizes real clinic videos as the key teaching tools to demonstrate clinical symptoms and how neurologists identify and diagnose them. Perfect for preparing for the neurology and neuromuscular boards, this book and accompanying videos have become an invaluable resource for neurology and neuromuscular training programs, while catering to the too-busy and often-overwhelmed modern doctor with its straightforward structure and language. All videos are supplemented with challenging multiple-choice questions to test the reader's knowledge and understanding. Each chapter is organized by cases, which start with a video, a description of the patient's symptoms, multiple choice questions, the diagnosis, and key references. This third edition, comprised of a total of 311 video cases (46 new), has several exciting new features and text to reflect the rapid advancement of medicine. The COVID-19 pandemic (caused by SARS-CoV-2) imposed tremendous challenges to the field of neurology and new videos are included to illustrate COVID-19 related neuromuscular disorders such as neuropathies and plexopathies. Videos also explore the pros and cons of virtual medicine, a practice expedited by the pandemic. A new chapter on the use of ultrasound, with 19 cases of videos and discussion, is now included. Videos of muscle and nerve biopsies are also included, as well as information about several new medications for myasthenia gravis, ALS and amyloidosis.

This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography.IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.

Klinik, Diagnostik und Therapie aller häufigen und seltenen Nervenkompressionssyndrome sind auch in der 4. Auflage des Buches fundiert und detailliert beschrieben. Ihre Behandlung ist eine interdisziplinäre Aufgabe, an der Neurologen, Neuroradiologen und Operateure unterschiedlicher Fachrichtungen (Handchirurgen, Neurochirurgen, Orthopäden und Unfallchirurgen, Plastische Chirurgen) mitwirken.Weitere Kapitel behandeln die elektrophysiologischen und bildgebenden Verfahren zur Diagnosestellung. Auch Sonderformen und die Abgrenzung zu fokalen Neuropathien anderer Ursache sind berücksichtigt.Die operativen Techniken sind mit zahlreichen Zeichnungen und Fotografien veranschaulicht. Über die SpringerNature MoreMedia-App können zudem Videos zur sonografischen Untersuchung und zu den Operationsverfahren aufgerufen werden.Ein Buch, das zum Thema Nervenkompressionssyndrom keine Frage offen lässt!

In spite of great improvements in prehospital, critical care, and surgical management, traumatic brain injury is still a leading cause of death and disability resulting in great socioeconomic burden. This book provides a comprehensive and practical perspective of the management of traumatic brain injury, from prehospital setting to discharge. Even more, the book highlights the importance of pathways (Trauma Center and Neurocritical Care Unit) and the central role of the specialized neurocritical care team and neurological critical care units in the practice of neurocritical care. Encouraging a practical, protocol-driven, multidisciplinary approach for both adult and pediatric patients, the authors provide a methodological description of the diagnostic and therapeutic management of patients with traumatic brain injury throughout the patient journey. Neuromonitoring assumes predominant importance, with an increasing role of noninvasive monitoring (near-infrared spectroscopy, Pupillometry, transcranial color Doppler-TCD, transcranial color duplex-TCCD, and optic nerve ultrasound) and neurophysiology (electroencephalography and evoked potentials) for early recognition of complications and rapid assessment of the effectiveness of medical treatment. However, the increasing amount of data increases the complexity of interpreting the collected information. The basic principles of multimodal monitoring and the computer-assisted method are presented to provide an overview of the future direction regarding the integration and interpretation of different data obtained from various techniques.Paying particular attention to prognosis and treatment-limiting decisions, the authors reviewed the critical role of neurorehabilitation and the clinical and bioethical perspective on brain death, organ donation, and communication with the family.

The second edition of the'IAN Textbook of Neurology'has been prepared for clinicians who participate in the care of neurological patients, including those who are in training to become neurologists, internists, neurosurgeons, and neuroscientists. The basic structure of this second edition has changed. The book is divided into seven parts. Section 1 discusses the History-taking and the Neurological Examination, inclusive of the systemic examination that helps the neurological diagnoses. Section 2 covers the Applied Neuroanatomy and Neurophysiology aspects that are important to clinicians. Section 3 discusses the clinical Approach to various Common Neurological Symptoms. Section 4 describes Diseases of the Nervous System. Section 5 discusses Investigations, Section 6 the Principles of Management, and Section 7 is about the Counseling and Doctor–Patient Relationship.

This fourth edition offers a practical guide to endovascular treatment of cerebrovascular disease and provides a comprehensive reference for the related neurovascular anatomy and the various disorders that affect the vascular system. Chapters cover fundamental principles underlying cerebral and spinal angiography; interventional techniques, devices, and practice guidelines; and commonly encountered cerebrovascular disorders for which interventional and endovascular methods are appropriateBuilding on the previous edition, the text is presented similarly in style and scope to emphasize accessibility and ease of reading. All chapters are fully updated to include more recent data, and obsolete products and techniques are replaced with the most current technology. Some key updates include:A greater emphasis on the use of radial artery access for the discussed endovascular techniques.The associations of COVID-19 with ischemic stroke and the implicationsof providing care for cerebrovascular patients during a pandemic.An extensive update to the acute ischemic stroke chapter with new references and format to more closely follow the format of other chapters in that section.Expansion of the pediatric sections of disease chapters, including discussions of genetic associations with disease. This is an ideal guide for clinicians and trainees in neurology, neurosurgery and neuroradiology, as well as practicing clinicians in related fields caring for patients with cerebrovascular disease.

Migraine Management, Volume 196 covers the effective treatment of migraines, including different subtypes of migraines in different patient populations. The classification and diagnostic criteria of common and uncommon subtypes of migraine is explored in detail, including childhood variants. An in-depth analysis of the pharmacology of acute and prophylactic agents is presented, along with an evidence-based review of pharmacologic management. This includes recently developed CGRP monoclonal antibodies and non-peptide small molecule CGRP antagonists. Advances in neuromodulatory treatments, both noninvasive and implantable, are also critically reviewed. Finally, specific treatment-related issues in pregnancy and lactation and childhood as well as the elderly are covered. Issues related to the diagnosis and management of vestibular migraine and the co-morbid disorder of persistent postural-perceptual dizziness is also explored. - Summarizes evidence-based best treatment for migraines - Differentiates treatment based on patient population, migraine type, and clinical setting - Includes pharmacological, biobehavioral, and physical treatments - Provides specialized treatments for children, the elderly, and pregnant patients

This book aims to collect research findings and provide insightful recommendations on various aspects of female epilepsy patients of childbearing age. This book discusses multidisciplinary effort of brain science, reproductive medicine, endocrinology, drug metabolism, genetics, maternal and infant medicine, etc. This book is written by a multidisciplinary team of researchers who had a passion for improving the quality of life of women with epilepsy, to demonstrate the latest scientific discoveries and precise management strategies for women with epilepsy in child-bearing age.

The book provides a comprehensive overview of sudden deafness. The volume comprises eleven chapters that are easy to read, amenable, and aim to address all commonly raised questions in daily practice. It starts with a chapter on the concept and epidemiology of sudden deafness, followed by the aetiology of sudden sensorineural hearing loss, diagnostic assessment, and MRI. The next chapter covers prognostic factors and recovery criteria. The remaining chapters elaborate on treatment options, and the closing chapter presents the available hearing aids for single-sided deafness (SSD). This book is the result of over 20 years of clinical experience, research, and knowledge dissemination on this disease. It will be a valuable resource for ENT specialists, neurology specialists, and family doctors.

Advances in Diagnostics and Immunotherapeutics for Neurodegenerative Diseases delves into the intricate mechanisms underlying neurodegenerative disorders and highlights cutting-edge diagnostic methods and innovative immunotherapeutic strategies. This comprehensive book addresses several key themes crucial to understanding and combating these debilitating conditions with an updated understanding of neurodegenerative disorders and a review of the latest advancements in diagnostic and treatment strategies.Key ThemesNeuroinflammation: examines the complex molecular pathways involved in neuroinflammatory responses and their impact on disease dynamics.Gut-Brain Axis: A thorough discussion on the relationship between the gut microbiome and neurodegenerative processes is presented.Advanced Diagnostics: A state-of-the-art review of diagnostic techniques provides updates on advanced neuroimaging modalities, cerebrospinal fluid biomarker analysis, and genetic testing.Epigenetic Regulation of Microglia: Covers the emerging field of epigenetic modifications and their role in modulating microglial activation and function.Immunotherapeutics: Learn about the potential of monoclonal antibodies, immune modulators, and repurposed drug therapies in slowing disease progression and improving patient outcomes.This book serves as a valuable resource for researchers, clinicians, and students in the fields of molecular biology, neuroimmunology, and clinical neurology.

Psychiatric symptoms (or mood/emotional disturbances) are diverse in patients with neurological diseases, that include depression, anxiety, emotional incontinence, anger, fatigue, and apathy. These symptoms are common; more than 1/3 of the patients suffer from these symptoms. Unfortunately, they have been neglected because 1) unlike other neurological symptoms such as motor dysfunction, speech disturbances or visual field defect, these symptoms are not visible and difficult to be noticed unless they are specifically examined by a physician who is properly educated on this problem 2) they are often not regarded as neurological symptoms either by the patients or their caregivers 3) they are relatively poorly studied by both neurologists and psychiatrists, and accordingly, are unfamiliar to the physicians. Especially, although `depression'is well known to physicians, other symptoms such as emotional incontinence, anger, fatigue or apathy are not appropriately assessed by physicians, and frequently misdiagnosed as depression. Moreover, there are difficulties in diagnosing depression in patients neurological diseases. For example, the individual items included in depression diagnosis such as sleep disturbances, appetite loss, or fatigue can result from neurological diseases or comorbid physical conditions in patients with neurological diseases. Therefore, a diagnosis of `depression'should be made cautiously. Finally, it should be understood that the importance of different mood/ emotional syndromes differ among various neurological diseases; for instance, although emotional incontinence and anger occur in as many as 20-30% of stroke patients, apathy and fatigue are more important symptoms than these for patients with neuro-degenerative disease.In clinical practice, recognizing these symptoms is important because they negatively affect the patients'quality of life, impair the functional recovery, increase the mortality, and increase the caregiver burden. Nevertheless, unlike other neurological symptoms such as motor/sensory dysfunction, and speech disturbances, they are relatively well managed mostly by pharmacological therapy such as selective serotonin re-uptake inhibitors (SSRI).The phenomenology of these neuropsychiatric symptoms and related factors, pathophysiological mechanism, and treatment strategies should be properly educated for neurologists, psychiatrists and other physicians. The book is written by experts in this field to disseminate important knowledges to neurologists, psychiatrists, psychologists and other physicians and will eventually benefit patients with neurological diseases.

The Oxford Textbook of Neurohaematology is a single source of knowledge on the diverse neurological conditions associated with malignant and classical haematological diseases. The book covers the full range of haematological diseases, both malignant and classical, that impact the central, peripheral, and autonomic nervous systems. The book is divided into three sections. In the first section, neurological conditions associated with malignant haematological diseases are presented. This section begins with chapters on primary haematological malignancies of the nervous system including primary central nervous system lymphomas, vitreoretinal lymphoma, and other rare primary malignancies such as Hodgkin disease and lymphoproliferative disorders. Next, a chapter on histiocytic tumours of the central nervous system presents the neurological conditions associated with the Langerhans and non-Langerhans histiocytoses. This is followed by chapters covering the neurological complications of systemic myeloid and lymphoid malignancies. The second section of the book covers neurological complications of the treatments used in the management of haematological malignancies such as chemotherapy, radiation, and immunotherapy including chimeric antigen receptor T cells. The third and final section of the book features chapters on the neurological complications associated with classical haematological diseases including disorders of red blood cells (e.g., sickle cell anaemia), disorders of platelets and coagulation (e.g., immune thrombocytopenia), and disorders of white blood cells (e.g., hyperviscosity syndrome). Edited by leading authorities in the field, this book will serve as a useful resource for neurologists, haematologists, and oncologists, as well as for subspecialists and allied health professionals involved in the management of haematological diseases and their neurological manifestations.

Auch in der 12. Auflage dieses Lehrbuchs wird wieder der aktuelle Stand zur Therapie des “idiopathischen Parkinson-Syndroms” vermittelt, leitlinienkonform wurde der Titel in Therapie der Parkinson-Krankheit angepasst. Alle wichtigen Therapieneuentwicklungen und -empfehlungen wurden aufgenommen (wie beispielsweise L-Dopa zum Inhalieren und für die subkutane Infusion sowie Apomorphin sublingual). So bleibt dieses Buch ein hochaktuelles Kompendium rund um alle relevanten Aspekte der Therapie der Parkinson-Krankheit, welches die tägliche Arbeit in Klinik und Praxis erleichtert.

This book is a comprehensive resource on acute neurorehabilitation consultations. When a patient first undergoes a traumatic brain or acquired spinal cord injury, an immediate consultation is needed with a rehabilitation specialist. In-depth literature reviews, practice guidelines, and case studies offer in-depth, practical coverage of the complete neurorehabilitation consultation with information on specific testing tools and metrics. The acute care consultant works in concert with other physicians and medical professionals, so throughout the text considerations on how to best organize the team to maximize care is carefully considered. Chapters also explore acute neurological sequelae, including arousal and stimulation, sleep, agitation, spasticity, and seizure prevention, for which an acute care consultant could provide important insight, treatment, and future management recommendations. The book concludes with advice on how to best transition patients from acute to long-term care, including patient prognostication and family education. This is an ideal guide for physiatrists and neurologists aiming to maximize recovery outcomes for their patients.

This revised, expanded third edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genome-wide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed.Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics. Each chapter now contains teaching/training MCQs to help with retention of information learnt from each chapter and this will be of considerable use to those training or about to the examined inthe field of inherited stroke.Additional questions via app: Download the Springer Nature Flashcards app for free and use exclusive additional material to test your knowledge.

In 2006, Daniel Gibbs, author of A Tattoo on my Brain: A Neurologist's Personal Battle against Alzheimer's Disease (soon to be a documentary produced by MTV/Paramount+), first noticed symptoms which he now knows to have been early signs of his Alzheimer's Disease. Daniel still writes every day, something he credits with keeping his mind sharper and his demons at bay. This book is a personal collection of essays written over the past two years that describe his own personal experiences, first treating patients with Alzheimer's, and now living with the disease himself. The book presents an up-to-date discussion of recent advances and setbacks in Alzheimer's research. Humane and hopeful, this book offers evidence-based information on how it may be possible even now to slow progression of the disease.

This book serves as a clinical guide for the growing number of Advanced Practice Clinicians (APC) who care for stroke patients. It covers the entire spectrum of stroke care: acute, inpatient, and outpatient, as well as fundamental topics like neuroanatomy and radiology. Each chapter succinctly reviews crucial topics designed to guide APCs of any experience level with clinical decision-making. To further enrich the text, we incorporated guidelines, relevant trial data written in plain language, decision-making algorithms, clinical pearls, and case vignettes. Since this is a book for APCs, each chapter is written in a clear, clinically focused manner by an experienced APC with a collaborating physician. We hope this is a helpful resource not only for APCs in neurology but also for those practicing in other specialties, primary care, and students learning about stroke care.

With an accurate and up-to-date approach, this book offers a comprehensive view of Parkinson's disease in the context of movement as a pillar of health. It compiles the current scientific knowledge supporting exercise therapy as a powerful tool to preventing and relieving symptoms, and to slowing the progression of Parkinson's disease. The work presents different therapeutic exercises, such as cueing, gait training, virtual reality, exergames, occupational therapy, electrostimulation, perturbed training, Qigong, and other methods. The pathophysiology, diagnosis, pharmacological interaction, motor and nonmotor symptoms, and the effects of exercise therapy are addressed in detail. Readers will learn to identify protective factors, to take precautions, to manage associated risks, and to dose the exercise load for Parkinson's. The work collects years of research and top-quality scientific evidence and goes beyond by presenting an innovative training planning proposal, which allows readers to prescribe exercise in a logical and quantitative way for patients with Parkinson's and other neurodegenerative diseases. Therapeutic exercise for Parkinson's Disease and Related Disorders is an essential work that provides new perspectives on how to prevent and reverse neurodegeneration. It is a must-read for healthcare professionals, students, and all those committed to improving the quality of life of people with Parkinson's disease.

This book provides clinicians with a comprehensive resource on the topic of respiratory complications of neuromuscular disease. It includes chapters by neurologists, pediatric pulmonologists, adult pulmonologists, anesthesiologists, and sleep physicians. The book begins with a review of the pathophysiology and epidemiology of the neuromuscular diseases that affect the respiratory system. It then includes chapters on pediatric concerns and the transition from pediatric providers to adult providers. There is additionally a focus on various therapeutic approaches and the monitoring of noninvasive ventilation. Finally, it includes a chapters on secretion clearance, palliative care and end of life decision making. The book appeals to a broad medical audience including adult pulmonologists, pediatric pulmonologists, respiratory therapists, nurses, sleep medicine providers, and neurologists.

This book focuses on rehabilitation demonstrating how translational research may help clinicians in boosting neural plasticity and functional recovery. Translational Neurorehabilitation is a new interesting field that seeks to produce more meaningful, applicable rehabilitation results that directly enhance human health, performance and quality of life. As neurological diseases increase with age and people who survive a brain injury are rising, thanks to the improvement of intensive acute care, the need to appeal to neurorehabilitation will double in the next few years. Motor, cognitive and behavior approaches have changed over the years and novel tools to treat brain and spinal cord injury should be validated before translating them into clinical practice. The book is aimed to expand the current understanding of brain function and disease by evaluating preclinical and clinical trials on neural plasticity and functional recovery after nervous system disorders. Also, it disseminates the knowledge coming from novel therapies, including advanced robotic and ICT-based applications. The book will be of interest to neuroscientists, physiatrists, neural engineers, and clinical neurologists.

The past decade has witnessed a revolution in our understanding of microglia, especially since their roles in the healthy CNS have started to unravel. These cells were shown to actively maintain health, in concert with neurons and other types of CNS cells, providing further insight into their crucial involvement with diseases. Edited by Drs. Marie-Ève Tremblay and Alexei Verkhratsky, Microglia: Physiology, Pathophysiology and Therapeutic Potential shares with the scientific and medical community the latest discoveries in the microglial research field, with a truly comprehensive collection of chapters written by the top specialists across five continents. The book begins by explaining briefly what they are, from both historical and evolutionary points of view, and how they can be studied. The first section explains their physiological roles in the maturation, function, and plasticity of the CNS. The second section focuses on their general involvement in neuropathophysiology, and the third section on their critical implication in specific CNS diseases, including neurotrauma, neuropathic pain, ischemia and stroke, infectious diseases, autoimmune diseases, neurodevelopmental and neuropsychiatric disorders, substance use and addiction, sleep disorders, ageing, and neurodegenerative diseases. The fourth section presents their clinical potential as a targeted therapeutic tool for these CNS diseases.

This book covers all diagnostic and therapeutic aspects of neuro-oncological diseases. In the last decade, the management of brain tumors has been revolutionized following the new WHO classification and thanks to the introduction of molecular markers into the clinical routine. From an imaging point of view, the continuous technological developments and the implementation of various radiopharmaceuticals have paved the way to new clinical indications and has helped optimize patient management. In this context, a major breakthrough could derive from the introduction of radiomics and artificial intelligence in the diagnostic and therapeutic pathway. Not forgetting the emerging role of heavy-ion therapy as a complement to the innovative drugs and treatments adopted in medical oncology and radiation therapy. In the present book, all above-mentioned aspects are covered, starting with the novel standards for the WHO classification of brain tumors, to the up-to-date surgical techniques and advanced therapeutic approaches, passing through the currently available imaging modalities and ongoing developments embracing both radiology and nuclear medicine discipline. Imaging represents indeed the “trait d'union” for all the arguments described in the book; therefore, in most chapters there are dedicated sessions focused on the role of imaging in each specific context. The publication aims to fill the gap between the clinicians and all professionals directly involved in the management of patients with brain tumors and the newest scientific outreach. Moreover, thanks to the comprehensive insight into the latest technological developments, scientists and researchers interested in the topic will find the book a useful tool for future studies and perspective discoveries.

This book covers experimental theory and practice of yoga that have enhanced its neuroscientific understanding. This is an excellent handbook for the researchers in the field of evidence-based integrative health. It encompasses traditional and modern tools used in neuroscience. It also provides information for the modern biologists, physicians and policymakers, of how mind-body complexities in neuroscience, mental health and preventive healthcare can be useful for health and disease. It serves as a guide for integrative health practitioners, patients, educationists, philosophers, graduate students and faculty pursuing research in the field of biology, complimentary medicine, and other alternative therapies. The chapters in this book also serve as a comprehensive resource for clinical trials in Yoga. In addition, flow charts and illustrations have been provided to understand how healthy brain ageing can be achieved.

Die Neurotologie ist ein Teilgebiet der Medizin, das sich mit der Diagnose und Behandlung neurologischer Erkrankungen des Innenohrs und der damit verbundenen Strukturen befasst. In jüngster Zeit wurden zahlreiche Fortschritte in der Neurotologie erzielt, die in Fachzeitschriften für Allgemeinmedizin, HNO-Heilkunde und Neurologie veröffentlicht wurden. Dieses umfassende Buch fasst diese Informationen zusammen, um ein vollständigeres Bild vom Stand des Fachgebiets zu vermitteln, und bezieht die eigenen klinischen Erfahrungen der Autoren ein. In letzter Zeit hat das Interesse an der Neurotologie deutlich zugenommen, was sich in den klinischen Erfahrungen und den Forschungsarbeiten und Veröffentlichungen von HNO-Ärzten, Neurologen, Neuro-Ophtalmologen, Audiologen und Physiotherapeuten zeigt. Es handelt sich also um ein Werk auf dem neuesten Stand der Technik, das alle aktuellen neurophysiologischen Daten über das vestibuläre System enthält. Man schätzt, dass 10% der Patienten, die sich in einer Notfallklinik vorstellen, vestibuläre Störungen, einschließlich Schwindel, haben, und diese Störungen sind häufig eine Ursache für Stürze bei älteren Patienten. Andererseits behandeln viele Ärzte ihre Schwindelpatienten mit Vestibularisblockern, die zwar die Symptome behandeln, aber die Störungen nicht heilen. Wir halten es für wichtig, eine Informationsquelle zum Gleichgewichtssystem und zu Gleichgewichtsstörungen bereitzustellen, und dieser Titel wird dies auf umfassende Weise tun. Dieser Titel ist ein ideales Nachschlagewerk für HNO-Ärzte, Neurologen, Neuroophtalmologen, Audiologen und Physiotherapeuten für die Diagnose und Behandlung von Gleichgewichtsstörungen. Die Übersetzung wurde mit Hilfe von künstlicher Intelligenz durchgeführt. Eine anschließende menschliche Überarbeitung erfolgte vor allem in Bezug auf den Inhalt.

Die Behandlung mit repetitiver transkranieller Magnetstimulation (rTMS) wird zunehmend zum Standard bei der Behandlung von Patienten mit Depressionen, unterstützt durch eine rasch wachsende Forschungsbasis. Dieser prägnante klinische Leitfaden dient als Nachschlagewerk und praktisches Werkzeug für Kliniker, die mit dieser Behandlungstechnik arbeiten oder sie kennenlernen möchten. Die einleitenden Kapitel enthalten grundlegende Informationen über die Geschichte und Entwicklung der rTMS-Behandlung und ihren Wirkmechanismus. Die Anwendung der Behandlung bei Depressionen wird dann im Detail behandelt, wobei die Evidenzbasis erläutert und eine Vielzahl klinischer Fragen erörtert wird. Die Nebenwirkungen der Behandlung werden diskutiert, und die Einrichtung von rTMS-Behandlungsprogrammen wird erklärt. Es gibt einen aktualisierten Überblick über den Einsatz von rTMS-Anwendungen bei anderen psychiatrischen Erkrankungen wie Zwangsstörungen. Weitere Kapitel befassen sich mit dem Einsatzvon tiefer TMS, Theta-Burst-Stimulation, beschleunigten Formen der rTMS und was bei Patienten zu tun ist, die nicht auf die erste Therapie ansprechen. Darüber hinaus werden die verschiedenen Ansätze für eine zielgerichtete Behandlung im Detail dargestellt. Dieses Buch vermittelt dem rTMS-Praktiker und jedem Interessierten eine aktuelle und umfassende Übersicht und bietet umfangreiche praktische klinische Ratschläge.

This official textbook of the Society of Neurocritical Care (SNCC) comprises a comprehensive review of all possible neurologic conditions that one may encounter in the practice of neuro-intensive care. It covers various topics, from the history and origin of neuro-intensive care to psychological and nursing care. Neurocritical care is the intensive care management of patients with life-threatening neurological and neurosurgical illnesses such as massive stroke, bleeding in or around the brain (subarachnoid hemorrhage, intracerebral hemorrhage, subdural hemorrhage, intraventricular hemorrhage), brain tumors, brain trauma, status epilepticus, nerve and muscle diseases (myasthenia gravis, Guillain-Barre Syndrome), spinal cord disorders and the cardiopulmonary complications of brain injury. Neurocritical care units specialize in managing the unique needs of such critically ill patients. The textbook is divided into many sections. Chapters discuss issues related to palliative care and describe some of the commonly performed procedures in the neuro-intensive care unit as well. It provides a straightforward and systematic approach to various clinical problems encountered during intensive care management of neurologic patients. It includes a separate section on special considerations in neurocritical care. The book includes ample figures, flowcharts and algorithms. The textbook is a valuable resource for residents, fellows and trainees in neuroanesthesia, neurointensive care, critical care, and anesthesia. It serves as a quick guide to all intensivists managing neurosurgical patients. It is also helpful for general intensivists who occasionally manages neurologic patients.

This book describes the theoretical background of the different forms of tinnitus (ringing in the ears) and detailed knowledge of state-of-the-art treatments of tinnitus. Tinnitus has many forms, and the severity ranges widely from being non-problematic to severely affecting a person's daily life. How loud the tinnitus is perceived does not directly relate to how much it distresses the patient. Thus, even tinnitus very close to the hearing threshold can be a disabling symptom. It can reduce the quality of life by generating anxiety and concentration problems, impairing the ability to do intellectual work, making it difficult to sleep, causing depression and sometimes even leading to suicide.Textbook of Tinnitus has filled a void by providing a comprehensive overview about the different forms of tinnitus, their pathophysiology and their treatment. However, since the publication of the first edition of the Textbook of Tinnitus in 2011, tinnitus research has dramaticallyevolved. In view of the substantial increase in knowledge, most chapters in this second edition are newly written and a few original chapters have had major updates. This edition has nine sections, covering the basics of tinnitus, the neurobiology of tinnitus, pathophysiological models, animal research, diagnosis and assessment, various forms of management and treatment, and finally, a look at the future of tinnitus and tinnitus research. The book will be of great interest to otolaryngologists, neurologists, psychiatrists, neurosurgeons, primary care clinicians, audiologists and psychologists, and students. Because of its organization and its extensive subject index, Textbook of Tinnitus, Second Edition can also serve as a reference for clinicians who do not treat tinnitus patients routinely.

This book represents a significant advance in the field of evidence-based acupuncture, specifically in regard to neurological disorders. It is a testament to the promising future of acupuncture, integrating the complexities of the human brain with the healing art of acupuncture. Each chapter leads readers to an expanded perspective where past and future, tradition and technology, converge in the pursuit of healing and well-being. In recent decades, technologies like functional magnetic resonance imaging (fMRI) have revolutionized our understanding of the human brain, enabling scientists to observe the brain's response to acupuncture in real-time. Tracing the pathways from acupoint to brain structure reveals fresh insights on the therapeutic function of acupoints and meridians. Participate in this journey to understand how acupuncture influences the brain, exploring new frontiers in the treatment and understanding of brain-related conditions. This book offers a rich blend of traditional healing wisdom and contemporary scientific insight.

Machine learning (ML) and deep learning (DL) have become essential tools in healthcare. They are capable of processing enormous amounts of data to find patterns and are also adopted into methods that manage and make sense of healthcare data, either electronic healthcare records or medical imagery. This book explores how ML/DL can assist neurologists in identifying, classifying or predicting neurological problems that require neuroimaging. With the ability to model high-dimensional datasets, supervised learning algorithms can help in relating brain images to behavioral or clinical observations and unsupervised learning can uncover hidden structures/patterns in images. Bringing together artificial intelligence (AI) experts as well as medical practitioners, these chapters cover the majority of neuro problems that use neuroimaging for diagnosis, along with case studies and directions for future research.

In the last 15 years, a combination of detailed clinical, genetic, molecular electrophysiological and immunological research has combined to result in a deep understanding of a subgroup of neurological diseases spanning the central and peripheral nervous system and which have become known collectively as the Neurological Channelopathies.Ion channels are critical membrane bound proteins that underpin many fundamental processes in the central and peripheral nervous system including action potential generation and propagation and the control of neurotransmitter release at all CNS synapses as well as at the neuromuscular junction. Ion channels are consequently essential for all motor actions, cognitive functions and sensory perceptions. Although it was originally considered that significant ion channel dysfunction would not be compatible with life, we now know this is often not the case, although severe disease can often be the result. Given the fundamental processes that are dependent on ion channel function, it is perhaps unsurprising that genetic or immunologically mediated ion channel dysfunction can result in almost any neurological symptom; patients may present to virtually any subspecialty within both adult and child neurology. The advances that have been made here have not only increased knowledge about the fundamental molecular mechanisms at play, but have also improved our ability to both diagnose and treat many of these disorders in clinical practice. Given these major advances, it is now the right time to combine this knowledge into a single HCN volume dedicated to the Neurological Channelopathies.The book will begin with an introductory overview highlighting common mechanistic themes that cut across different CNS and PNS presentations but with potential for common treatment approaches. This initial chapter considers the classification, genetics, and fundamental physiology of ion channels. Subsequent chapters present a detailed consideration of all genetic and immunological channelopathies. Each chapter will consider•Pathophysiological underpinnings - genetic or immunological•Clinical presentations•Diagnostic approach•Treatment and management - Identifies importance of ion channels to CNS & PNS function - Considers the classification, genetics, and physiology of ion channels - Presents all major immunological and genetic channelopathies - Provides clinical presentation, diagnosis, and treatment of channelopathies

Internet of Things and Machine Learning for?Type I and Type II Diabetes: Use Cases provides a medium of exchange of expertise and addresses the concerns, needs, and problems associated with Type I and Type II diabetes. Expert contributions come from researchers across biomedical, data mining, and deep learning. This is an essential resource for both the AI and Biomedical research community, crossing various sectors for broad coverage of the concepts, themes, and instrumentalities of this important and evolving area. Coverage includes IoT, AI, Deep Learning, Machine Learning and Big Data Analytics for diabetes and health informatics. - Integrates many Machine learning techniques in biomedical domain to detect various types of diabetes to utilizing large volumes of available diabetes-related data for extracting knowledge - It integrates data mining and IoT techniques to monitor diabetes patients using their medical records (HER) and administrative data - Includes clinical applications to highlight contemporary use of these machine learning algorithms and artificial intelligence-driven models beyond research settings

There are three aims of Injured Brains of Medical Minds II - Firstly, to provide perceptive accounts of symptoms and the natural history of brain disorders by people specially trained in the art of observing and reporting, thus yielding unique insights into the lived experience of what it is like to be a patient and to be disabled. Secondly, to offer insights into how the brain works, since the articles are written by patients who are uniquely privileged in view of their understanding of the brain. Thirdly, to highlight ways in which the conditions described in the book can be best managed and treated by healthcare professions and carers. Each chapter includes a set of articles by doctors and other healthcare professionals who have suffered a brain injury illness or brain injury, recounting their experience, accompanied by a commentary for each article. The commentaries critically examine the piece, relating it to current issues in neuropsychology, neurology and cognitive neuroscience. Accounts from over 40 individuals cover a wide range of conditions including: stroke, traumatic brain injury, Alzheimer's Disease and other forms of dementia, brain tumour, infectious and inflammatory conditions, multiple sclerosis, and epilepsy. Summaries are also included of recent books written by doctors/scientists who suffered a brain disorder. This second volume includes totally new articles and commentaries, providing a valuable insight into what it is like to suffer from a brain disorder as well as advice both to patients and practitioners as to what can best be done to improve everyday limitations resulting from a brain disorder. The first volume was published by Oxford University Press in 1997.

This book assembles, for the first time, information required for the recognition, understanding, and treatment of behavioral problems resulting from neurological conditions. Its focus is two-pronged: 1) on conditions where cognitive-behavioral manifestations are major symptoms, such as attention deficit hyperactivity disorder, autism, and developmental language disorder; and 2) on conditions where these symptoms are significant but secondary, such as brain tumors, epilepsy, and AIDS. This multi-authored guide also outlines effective approaches to behavioral therapy for these conditions. Pediatric Behavioral Neurology is an excellent resource for practitioners whose work demands knowledge of the symptoms, signs, and treatment of behavioral and cognitive disorders caused by brain abnormalities. It is comprehensive, yet concise and easy to use.

Hone your clinical reasoning and diagnostic skills with a new series of case-based topic-specific studies. This compilation of twenty neurology-related cases includes presenting clinical manifestations and a discussion of the broad range of possible diagnoses, with a reveal of the actual diagnosis at the end. Does this child have a classic presentation of a rare condition or an atypical presentation of a common diagnosis? Does the patient have a primary neurological condition or a neurological manifestation of a systemic disease? Several patients in this collection presented with ataxia, but their final diagnoses range from the unsurprising cerebellar tumor to uncommon conditions like heavy metal poisoning and rare genetic disorders. Does the child with diffuse weakness have a classic condition such as Guillain-Barré syndrome, a vitamin deficiency, one of the periodic paralyses, or an autoimmune disorder such as myasthenia gravis? Cases also include relatively new conditions such as autoimmune encephalitis or genetic disorders but remind us not to overlook well-known but now uncommon conditions like vitamin deficiencies or remote neurological dysfunction due to cancer in another organ.

This innovative book offers a multidimensional exploration of the epistemological foundations of psychiatry and its major disorders. By emphasizing the importance of phenomenology in unravelling the intricate interplay between basic categories of human experience and neurobiological processes, it advocates for a shift in both psychiatric research and clinical practice. Phenomenological Neuropsychiatry presents psychiatry as a hybrid discipline that synthesizes subjective mental experiences with objective neuroscientific findings and forms an integrative and interdisciplinary structure that provides a dialectical bridge between understanding, compassion, and explanation. The first section of the book presents the lived experience of psychosis and argues for a more inclusive approach to mental health issues. The second section examines the ways in which psychiatric knowledge is constructed and the unique challenges posed by combining understanding and explanation of mental disorders. Section three sheds light on how disruptions in bodily experiences, memory processes, and self-perception can contribute to the development and manifestation of psychiatric issues. The following section discusses disorders of mood and anxiety, including the phenomena of depression, obsessions, and depersonalization. The fifth and final section provides an in-depth examination of psychotic disorders. It covers a range of topics, such as timing, intentionality, self-monitoring of action in schizophrenia, and the neurobiology of prodromal psychosis. As a singular work dedicated to revitalizing and advancing cross-fertilization between psychiatry and phenomenology, this groundbreaking book clears the foggy operationalized clusters of mental symptoms that may obscure diagnosis and treatment and argues for systematic integration of patient subjectivity and collaboration in clinical research. It features an authorship of the leading clinicians and thinkers from throughout the world in psychiatry, psychology, neuroscience, social sciences, and philosophy. Phenomenological Neuropsychiatry: How Patient Experience Bridges the Clinic with Clinical Neuroscience is a major contribution to the clinical literature and a must-read for psychiatrists, neurologists, psychologists, and professionals and students from other disciplines concerned with absorbing a deeper understanding of psychiatric disorders.

This new second edition presents a completely new selection of 25 scenarios based on cases from the personal archive of Ondrej Dolezal, collected over 20 years of clinical practice. With a simple and uniquely innovative approach, this book offers a natural workflow through the chapter structure, helping junior doctors to gain confidence in reaching their clinical diagnosis. A range of different clinical scenarios and neurological conditions are examined, from cerebal palsy and other degenerative disorders, to epilepsy and headache. This book can serve as a teaching aid in a classroom setting, where the teacher introduces the case (“telling the story”, neurological examination) and the students then propose differential diagnoses and further tests. The teacher can show a representative test result to students and expect them to interpret the scan/test, as well as proposing further referrals and discussing the prognosis. Each chapter, contains visual aids in the form of Neuroexam, helping the reader gain a quick understanding of the case. Scenarios presented in this book can be used at the bedside in teaching medical students and junior doctors, and it is aimed at trainee neurologists and any non-neurologists who might encounter neurological cases in the clinic.