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With treatment approaches and the field of neuro-oncology neuroimaging changing rapidly, this third edition of the Handbook of Neuro-Oncology Neuroimaging is very relevant to those in the field, providing a single-source, comprehensive, reference handbook of the most up-to-date clinical and technical information regarding the application of neuroimaging techniques to brain tumor and neuro-oncology patients. This new volume will have updates on all of the material from the second edition, and in addition features several new important chapters covering diverse topics such as imaging for the use of Laser Interstitial Thermal Therapy, advanced imaging techniques in radiation therapy, therapeutic treatment fields, response assessment in clinical trials, surgical planning of neoplastic disease of the spine, and more. Sections first overview neuro-oncological disorders before delving into the physics and basic science of neuroimaging and great focus on CT and MRI. The book then focuses on advances in the neuroimaging of brain tumors and neuroimaging of specific tumor types. There is also discussion of neuroimaging of other neuro-oncological syndromes. This book will serve as a resource of background information to neuroimaging researchers and basic scientists with an interest in brain tumors and neuro-oncology. - Summarizes translational research on brain imaging for brain tumors - Discusses limitations of neuroimaging for diagnosis and treatment - Presents advanced imaging technologies, including CT, MRI, and PET - Contains new coverage on Laser Interstitial Thermal Therapy, radiation therapy, clinical trials, and more

Neurological Complications of Systematic Cancer and Antineoplastic Therapy, Second Edition provides an expanded, updated and in-depth review of common manifestations related to neurology that occur in patients with systemic cancer. These include brain metastases, spinal cord compression, cerebrovascular events, and leptomeningeal disease. The book also discusses neurological complications related to treatments such as radiation and chemotherapy and is an essential reference for the practicing neurologist and oncologist. Sections in this new release cover the pathophysiology and molecular biology of cancer and the metastatic phenotype, Metastatic spread to cranial and peripheral nerves and brachial and lumbosacral plexuses, Metabolic and nutritional disorders, CNS infections, Neurological complications of immunotherapy and bone marrow transplants, Neurological complications of new molecular agents and immuno-modulatory drugs, and more. Summarizes the neurologic effects of both cancer and cancer treatment Provides scientific and clinical information relevant to research and treatment Identifies neurological complications by tumor type and tumor therapy Covers GI, lung, breast, gynecological, head and neck cancers, and more Includes radiotherapy, chemotherapy, immunotherapy, and new drugs Contains melanoma, lymphoma, sarcoma, myeloma, leukemia, and more

Anatomical localization skills based in physical examination are essential for any clinician caring for patients with neurologic disease processes. Now fully revised and up to date, Localization in Clinical Neurology, 8th Edition, uses easy-to-read descriptions, full-color illustrations and videos to help readers understand and locate the source of a patient's signs and symptoms. This gold standard text now features dozens of clinical videos that help clinicians improve diagnostic accuracy and avoid unnecessary testing.

Develop and perfect your neurological localization skills with the gold standard text in the field. Anatomical localization skills based in physical examination are essential for any clinician caring for patients with neurologic disease processes. Newly revised and updated, Localization in Clinical Neurology, Seventh Edition, uses detailed, easy-to-read descriptions and full-color illustrations to help you understand and pinpoint the source of a patient's signs and symptoms. Improve your diagnostic accuracy and avoid unnecessary testing with this outstanding roadmap to neurologic diagnosis.

Remarkable progress in neuro-oncology due to increased utilization of advanced imaging in clinical practice continues to accelerate in recent years. Refinements in magnetic resonance imaging (MRI) and computed tomography (CT) technology, and the addition of newer anatomical, functional, and metabolic imaging methods, such as MRS, fMRI, diffusion MRI, and DTI MRI have allowed brain tumor patients to be diagnosed much earlier and to be followed more carefully during treatment. With treatment approaches and the field of neuro-oncology neuroimaging changing rapidly, this second edition of the Handbook of Neuro-Oncology Neuroimaging is so relevant to those in the field, providing a single-source, comprehensive, reference handbook of the most up-to-date clinical and technical information regarding the application of neuro-Imaging techniques to brain tumor and neuro-oncology patients. This new volume will have updates on all of the material from the first edition, and in addition will feature several new important chapters covering diverse topics such as advanced imaging techniques in radiation therapy, therapeutic treatment fields, response assessment in clinical trials, surgical planning of neoplastic disease of the spine, and more. It will also serve as a resource of background information to neuroimaging researchers and basic scientists with an interest in brain tumors and neuro-oncology. - Provides a background to translational research and the use of brain imaging for brain tumors - Contains critical discussions on the potential and limitations of neuroimaging as a translational tool for the diagnosis and treatment of brain tumor and neuro-oncology patients - Presents an up-to-date reference on advanced imaging technologies, including computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET), as well as the recent refinements in these techniques

The leading textbook in pain management – updated with the latest research and developments'This is an excellent, comprehensive textbook on all aspects of pain and is recommended for physicians in all specialties who deal with pain patients.'-- reviewing earlier edition in Anesthesia & Analgesia. This concise yet comprehensive text is a true one-stop resource for anesthesiologists and specialists in pain medicine. Every aspect of diagnosing and treating specific pain conditions and syndromes are covered, including physiology, physical and laboratory diagnosis, and therapeutic interventions. While thorough and encompassing the entire curriculum of clinical pain management, the book has been carefully edited to be a manageable length and not overwhelming to readers. Reflecting the fact that pain medicine is a true multidisciplinary specialty, a new co-editor who is a pain psychologist at Beth Israel Deaconess has been added. The third edition also features a greater emphasis on risk management and an updated Interventional Pain Section highlighted by an increased number of figures and a stronger clinical focus. Key clinical concepts are summarized at the end of each chapter Numerous tables and figures highlight the most important concepts and procedures

Disorders of the peripheral nervous system (PNS) are the cause of prominent neurological symptoms including weakness, sensory loss, pain and autonomic dysfunction associated with deficits, morbidity and mortality. These disorders may be primary hereditary or cryptogenic neurologic disorders confined to the PNS or part of the pathology of both the central nervous system and the PNS. Most PNS disorders are secondary to other system disorders and may be responsive to treatment of the primary disease. Important advances have been obtained in several areas including molecular genetics, biochemistry, immunology, morphology and physiology that have enhanced our understanding of the causes and consequences of damage to peripheral nerve. Understanding of both these groups of PNS diseases has greatly expanded over recent years and has led to important advances of treatment both to protect and to repair damages of peripheral nerve. This volume provides an overview of the state-of-the-art of examination, diagnosis and treatment of these very diverse disorders and will be of interest to both the research and clinical neuroscience and neurology communities. - Covers both hereditary and cryptogenic neurologic disorders - Includes advances in the basic science of PNS from molecular genetics, biochemistry, immunology, morphology and physiology - Detailed coverage of neuropathy in connective tissue disorders, infectious disorders, metabolic disorders and malignancy

Neurooncology has become a science of such great proportions and indefinite limits as to include branches which widely diverge from one another. Therefore, it is not an easy task to fit it all into the narrow framework of a book, though the collaboration among scientists compensates partly for the varying depths of knowledge and ex­ perience in the individual disciplines. The principal characteristic of this work, how­ ever, is in casting'pathology'as the common nosographic link. Though scientific progress has brought us well past the nosography of brain tu­ of departure, the area of mutual understanding to mors, pathology remains the point which all students of neurooncology refer when laying out diagnostic, therapeutic, and research schedules. Neurologists, neurosurgeons, and neuroradiologists orient themselves only by referring to tumor types. Neurooncology treatises require ever greater numbers of authors in order to cover the different subject areas with uniform authority. Excellent texts are available today for this purpose. The present book is not, and does not wish to be, a treatise but rather aims at presenting different aspects of neurooncology from the perspective of pathology and its biological and clinical correlates. It expresses the author's experi­ ence in the study of brain tumors and their pathology and clinical characteristics. The emphasis dedicated to the subjects relates to the clinicopathological and theore­ tical importance.

Neuro-Oncology—a new title in the Blue Books of Practical Neurology series—is a concise and clinically applicable guide to this dynamic subspecialty. Jeremy Rees, PhD, MRCP and Patrick Y. Wen, MD present the most current information on the treatment and management of primary CNS tumors, secondary brain tumors, and the neurological complications of other cancers and their therapies in a format and scope appealing to both the general neurologist and the subspecialist. Access comprehensive coverage of treatment for adult and pediatric conditions—including tumors of the spinal cord as well as the brain. Find coverage of recent advances easily thanks to the emphasis on the latest clinical and laboratory findings and their implications for clinical management and treatment. Apply the possibilities and outcomes of neuro-oncologic surgery within the context of neurologic practice. Address the neurologic complications of cancer and its treatment as well as of primary and secondary tumors. Tap into the global perspectives of experts from all around the world for a multi-disciplinary approach to practice.

Neurological Complications of Systematic Cancer and Antineoplastic Therapy provides an in-depth review of common manifestations related to neurology that occur in patients with systemic cancer. These include brain metastases, spinal cord compression, cerebrovascular events, and leptomeningeal disease. The book also discusses less common complicatio

Patients with cancer can suffer from a bewildering variety of neurologic signs and symptoms. The neurologic symptoms are often more disabling than the primary cancer. Symptoms including confusion, seizures, pain and paralysis may be a result of either metastases to the nervous system or one of several nonmetastatic complications of cancer. The physician who promptly recognizes neurologic symptoms occurring in a patient with cancer and makes an early diagnosis may prevent the symptoms from becoming permanently disabling or sometimes lethal. This monograph, an update of the first edition published in 1995, is divided into 3 sections. The first classifies the wide variety of disorders that can cause neurologic symptoms the patient with cancer, discusses the pathophysiology of nervous system metastases, the pathophysiology and treatment of brain edema and the approach to supportive care of common neurologic symptoms such as seizures, pain, and side effects of commonly used supportive care agents. The second section is devoted to nervous system metastases, addressing in turn, brain, spinal cord, meningeal and cranial and peripheral nerve metastases, describing clinical symptoms, approach to diagnosis and current treatment. The third section addresses several nonmetastatic complications of cancer and includes sections on vascular disease, infections, metabolic and nutritional disorders, side chemotherapy, radiation and other diagnostic and therapeutic procedures. The final chapter addresses paraneoplastic syndromes. The book is intended for practicing oncologists, neurologists, neurosurgeons and radiation oncologists as well as internists who treated patients with cancer. Our attempt was to write a book that would assist oncologists in understanding neurologic problems and neurologists in understanding oncologic problems. The book is also intended for physicians training to specialize in any of the above areas. It includes a practical approach to the diagnosis and management of patients with neurologic disease who are with known to have cancer or in whom cancer is suspected.

Neuro-oncology has evolved substantially as a clinical and research discipline over the past few decades. Cancer Neurology in Clinical Practice: Neurologic Complications of Cancer and its Treatment, Second Edition provides clinicians from various backgrounds and levels of training with a reference to help focus the differential diagnosis, treatment strategy, and management plan for the cancer patient with neurologic symptoms and findings. The volume begins with an overview of the field of neuro-oncology and a review of the role of neuroimaging in the diagnosis of neuro-oncologic disease. Several chapters on interpretation and management of common neuro-oncologic symptoms follow. Subsequent sections contain chapters on the direct and indirect neurologic complications of cancer as well as complications of therapy. The final section focuses on the spectrum and management of neurologic disease in patients with cancer of specific organs. Cancer Neurology in Clinical Practice: Neurologic Complications of Cancer and its Treatment, Second Edition is an important new work that aims to broaden and deepen the familiarity of clinicians with the range and management of neuro-oncologic diseases in order to improve the quality of care for cancer patients.

Although the field of Neuro-Oncology has grown considerably in the last 10 to 15 years and has a rather extensive literature, there are no comprehensive,'single-source books that summarize the current literature and future trends of neuroimaging in neuro-oncology. This book covers this topic in more comprehensive fashion, making it an important addition to the armamentarium of physicians that care for patients with brain tumors and other neuro-oncological disorders. Well-founded in basic science, it includes chapters that provide an overview of relevant background material in critical areas such as physics, contrast agents, ultra-high field brain MRI, and molecular imaging.

This brand-new text provides you with an easy-to-use, comprehensive reference that features a clinical perspective balanced with relevant basic science. Inside, you'll find discussions of the latest research and how it has led to a greater understanding of the cause of disease, as well as burgeoning tests and the latest therapeutic agents available. From Alzheimer's disease to vestibular system disorders, you'll find the practical guidance you need to diagnose effectively and provide an appropriate therapeutic approach for each individual case. Plus, a templated, four-color design offers you easy access to pertinent informationIntegrates basic science with clinical neurology to help you better understand neurologic diseases and provide the most accurate diagnosis and best treatment plan for each patient.Discusses the latest research results and offers new information on treatment options.Features the expertise of international authorities, providing a worldwide perspective.Uses a templated, four-color format that makes information accessible and easy to understand-particularly the basic science concepts.

In Cancer Neurology in Clinical Practice, leading neuro-oncologists from around the world comprehensively review the neurologic symptoms that cancer patients experience, and show how they should be interpreted and evaluated. Organized by both symptom and organ, the book carefully describes each diagnostic neurologic entity-from symptomatology to diagnostic studies to management and prognosis-and presents each major type of cancer in terms of it neurologic problems and how they should be handled. The role of surgery, radiation, chemotherapy, and other palliative measures are considered for each type of problem. Multidisciplinary and up-to-date, Cancer Neurology in Clinical Practice explains to the busy physicians treating cancer patients the latest findings in neuro-oncology that will help them to focus their differential diagnosis, diagnostic strategy, and treatment plan for the cancer patient with neurologic symptoms and findings.