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The optimal management of children who receive dialysis therapy requires a thorough understanding of the multidisciplinary nature of their treatment. The multiple organ systems that are often impacted by acute and chronic impairment of kidney function makes the care of this patient population highly complex. This 3rd edition of Pediatric Dialysis provides authoritative and comprehensive information on all aspects of dialysis-related care for children to assist the clinician in achieving the best possible patient outcomes. Like the two preceding editions, the 3rd edition enlists experts from North America, South America, Europe, and Asia to provide their perspectives on virtually all issues pertaining to dialysis-related management for children, based on years of clinical and research experience. The book contains sections on all essential topics including when to initiate dialysis, peritoneal dialysis, hemodialysis, managing secondary complications, nutritional therapy, drugs and dialysis, dialysis outcomes, and transition to adult care. Each chapter has been thoroughly updated in terms of content and references. The book also includes several new chapters on topics such as remote patient monitoring, acute kidney injury management in the developing world, and antibiotic stewardship in the dialysis unit, maintaining the text's preeminent status as a worldwide source for pediatric dialysis care.

Offering practical guidance for all members of the transplant team, Kidney Transplantation, Principles and Practice, 8th Edition, provides the balanced, up-to-date information you need to achieve optimal outcomes for your patients. A global team of internationally renowned surgeons and nephrologists, many new to this edition, offers fresh perspectives on everything from applied science and surgical techniques to immunosuppressive methods, outcomes, risks, and medical considerations related to kidney transplantation, in both adults and children. - Offers state-of-the-art coverage of all areas of kidney transplantation such as preservation of kidneys; mechanisms of rejection and the induction of tolerance; techniques of laparoscopic live donor nephrectomy; and immunosuppression. - Contains up-to-date outcomes data and analysis of the evidence supporting current practice in the field. - Includes new information on desensitization and considerable new data on the clinical use of costimulation blockade. - Keeps you current with new chapters on kidney allocation policy that reflects the ethical and societal values of different countries and populations; and biomarkers of kidney injury and rejection, including the need for better monitoring tools to guide therapy and patient management. - Covers hot topics such as management of chronic allograft failure, the sensitized patient and antibody-mediated rejection, and paired exchange principles. - Features hundreds of superb illustrations to help you visualize key concepts and nuances of renal transplantation. - Provides dynamic visual guidance with new real-time video coverage of ultrasound-guided pancreas allograft biopsy; a new animation of calcineurin inhibitor mechanism of action animation; and videos that demonstrate the formation of an immune synapse, 3-D rotational images of immune synapses, an NK cell killing its target, peritoneal dialysis-catheter insertion techniques, laparoendoscopic single site (LESS) donor nephrectomy, and more. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices

This book provides a comprehensive and systematic review of the latest findings in a wide spectrum of clinically important aspects of chronic kidney disease (CKD), focusing on clinical diagnosis and therapeutics. CKD is a global health problem with a rising morbidity and mortality. The last decade has seen significant improvements in determining the incidence, prevalence, and complications of CKD, mainly thanks to the definitions of CKD developed by the National Kidney Foundation's Kidney Disease Outcomes Quality Initiative (K/DOQI). However, increased recognition of CKD has led to awareness of the limitations of its clinical diagnosis and treatment, which are essential to patients'wellbeing. This book is of particular value not only to nephrologists, but also to general practitioners and residents with an interest in CKD. It offers a well-organized exposition of the current knowledge base. Compared with previously published books on kidney disease and CKD, it has a smaller number of more concise chapters. As a result, readers can easily obtain an overview of the most important topics in CKD. We hope that practitioners will gain as much from reading this practical guide to clinical management of CKD as we have from editing it.

••Selected for Doody's Core Titles® 2024 in Transplantation Surgery•• From basic science to practical clinical tools, Chronic Kidney Disease, Dialysis, and Transplantation, 4th Edition provides you with the up-to-date, authoritative guidance you need to safely and effectively manage patients with chronic renal disease. Covering all relevant clinical management issues, this companion volume to Brenner and Rector's The Kidney presents the knowledge and expertise of renowned researchers and clinicians in the fields of hemodialysis, peritoneal dialysis, critical care nephrology, and transplantation – for an all-in-one, indispensable guide to every aspect of this fast-changing field. - Contains expanded content on economics and outcomes of treatment, as well as acute kidney injury. - Covers hot topics such as the genetic causes of chronic kidney disease, ethical challenges and palliative care, and home hemodialysis. - Discusses the latest advances in hypertensive kidney disease, vitamin D deficiency, diabetes management, transplantation, and more. - Provides a clear visual understanding of complex information with high-quality line drawings, photographs, and diagnostic and treatment algorithms. - Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Is the nephrology community facilitating excess cardiovascular deaths in patients with kidney failure and anemia by treating to a subnormal hematocrit? Why have clinicians and nephrologists permitted health insurance companies and the government to decide when anemia therapy should begin in persons with progressive kidney failure? Is iron the only variable that can be manipulated to maximize response to recombinant erythropoietin? Are we using too much intravenous iron in kidney failure patients, and is oral iron supplementation worthless in sustaining iron stores during long-term erythropoietin treatment? When does left ventricular hypertrophy begin to emerge in patients with progressive renal disease and is there convincing evidence that anemia is a significant cause of LVH in this setting? Is darbepoetin alfa, a new novel, long-acting erythropoietin, really superior to recombinant erythropoietin? This book is a compilation of proceedings from a conference in Brooklyn convened to address these and other controversial and unresolved issues in renal anemia management.

With meticulous updates throughout, Kidney Transplantation remains your definitive medical resource for state-of-the-art answers on every aspect of renal transplantation. A multidisciplinary approach from internationally renowned nephrologists from around the world offers practice-applicable guidance for all members of the transplant team. With coverage encompassing applied science, surgical techniques, immunosuppressive methods, outcomes, risks, and medical considerations related to kidney transplantation, both in adults and children, you'll have the balanced information you need to achieve the best possible outcomes.Visualize key concepts and discern nuances of renal transplantation techniques through more than 335 superb illustrations.

More than half a million people worldwide are now sustained by renal replacement therapy, mainly hemodialysis at a cost exceeding USD 30 billion per year. Each case of ESRD that is delayed or prevented saves funds that may be applied to other aspects of health care. Edited by an internationally renowned nephrologist, Prognosis for Kidney Disorders provides a timely summary of exciting work in progress directed toward renoprotection and of ultimate interdiction of ESRD. Suitable for researchers and clinicians, Dr. Morrell Michael Avram has collected and commented on promising initiatives likely to enter everyday practice in the immediate future. Suitable for renal trainees, experienced kidney doctors, nurses, nutritionists and cardiologists.

The leading textbook on the subject. A completely rewritten and up-to-date fifth edition, based upon the highly respected fourth edition, edited by C. Jacobs, C.M. Kjellstrand, K.M. Koch and J.F. Winchester. Considered the global resource for dialysis specialists, dialysis manufacturers and scientists for over two decades, this authoritative, highly acclaimed major reference work has been completely rewritten and revised in a much-awaited 5th edition. All previous chapters have been updated to include the very latest advancements and understandings in this critical and complex field. New sections include those on computerization of dialysis records, online monitoring and biofeedback, patient sexual function, patient selection and integration, use of exercise in improving patient health, design of randomized trials, and more. This new edition is truly global in scope and features the contributions the top experts from around the world.

In 1994, the expert knowledge of Ram Gokal and Karl D. Nolph, the two foremost figures in the field of peritoneal dialysis, was combined to produce the first edition of the Textbook of Peritoneal Dialysis. The work quickly became recognised as the `gold standard'for those working in the field. Since its conception, however, our understanding of peritoneal dialysis related physiology, kinetics and clinical outcomes, as well as the concepts of intraperitoneal chemotherapy, has increased sufficiently to make an updated and completely revised edition of the work necessary. An expansion of the editorial team by fellow-experts Ramesh Khanna and Raymond Krediet enabled an even more comprehensive approach to be taken. This second edition reasserts the book's uniqueness in its detailed discussion of the topic, making it required reading for all those working within the field of peritoneal dialysis.

developed. When I did not identify European colleagues In this rapidly evolving field it is appropriate to update frequently our state of the art knowledge of uremia therapy. who had the expertise who could expend the time and with Hence, this third edition of Replacement of Renal Function whom I could work so smoothly, I began alone. by Dialysis appears before many of its predecessors have Although I was tempted to ask all the same authors as had been destroyed by normal wear and tear over 11 and 6 years written so well previously to contribute again, I realized that the new edition must be revitalized. Accordingly a fraction of use, respectively. The first two editions of this book were designed to be of the authors changed, some new topics have been added integrated comprehensive reviews of the pertinent aspects and others have been deleted. The multinational character of dialysis and related fields with sufficient clarity for the of authorship has been maintained. Existing chapters have novice to learn, yet adequate depth for the expert to rely on been rewritten thoroughly, and new authors have provided them as encyclopedic desk references on renal replacement as requested a full discussion and bibliography in keeping therapy. Based on the favorable readers'comments and with the previous editions.

In 1986 the first edition of Continuous Ambulatory Peritoneal Dialysis, edited by R. Gokal, was published. In 1989 the third edition of Peritoneal Dialysis, edited by K.D. Nolph, was published. Both books were widely recognized for their comprehensive discussion of this particular field. Rather than edit new editions of each of these books separately, two of the most prominent figures in this field have decided to combine their knowledge and enthusiasm in this single book: The Textbook of Peritoneal Dialysis. The book is unique in its detailed discussion of a complete range of topics, including new advances in our understanding of the physiology of peritoneal dialysis, peritoneal dialysis kinetics, clinical results and a chapter dealing with the concepts of intraperitoneal chemotherapy. These examples of the dynamic nature of the field further illustrate the importance of this textbook, and make it required reading for everybody working within the field of peritoneal dialysis.

Since the inaugural publication of Pediatric Dialysis in 2004, a wide range of advances have taken place in dialysis-related care, leading to a wealth of new knowledge in the field. Pediatric Dialysis, Second Edition brings this knowledge together to provide the most comprehensive source of state-of-the-art information on the dialysis of infants, children and adolescents. With new chapters, updated chapters and references, and contemporary, unique perspectives from authors who are leaders in the global pediatric nephrology community, Pediatric Dialysis, Second Edition is, once again, an authoritative reference that will facilitate best practices in both acute and chronic dialysis. Experienced clinicians and trainees alike will find Pediatric Dialysis, Second Edition not only another valuable contribution to the literature but an indispensable guide to managing their pediatric patients on dialysis.

During the past quarter century there has been a renaissance of interest in the use of peritoneal dialysis as the primary dialytic modality for the treatment of children with end-stage renal disease (ESRD). The development of continuous ambulatory peritoneal dialysis (APD) has facilitated the provision of prolonged dialysis to infants, children and adolescents and has provided pediatric nephrologists worldwide with a real opportunity to administer effective dialysis therapy to all patients afflicted with ESRD. It has been more than a decade since the initial publication of CAPD/CCPD in Children. In the interim, a great deal of clinical experience with patients receiving peritoneal dialysis has been accumulated and research efforts have substantially increased our understanding of the technique. Therefore, we felt that a second edition of CAPD/CCPD in Children was propitious to update the advances of the past decade.

The master tool of logic is the syllogism. If A> Band B> C, then it must follow as the night the day that A > C. If the major and minor premises are true or scientifically correct by current knowledge, the conclusion is true or at least scientifically correct by current knowledge. The demographer of today beams a clear message, which if not true is at least scientifically correct by current knowledge. In the first 80 years of the Twentieth Century, the'over-65'population of Americans increased eight­ fold. By century's end it will have increased 12-fold and shortly thereafter will include one in five Americans. While initially a fact of the developed world, the pace of similar graying is accelerating even more rapidly in the Second and Third Worlds. This gray delta constitutes about 35 million living Americans, who may use one-half or more of the health care resources. A would have to be a lot more foolish than B if they failed to recognize that in the coming decade the causation, case-mix, and area of the gray delta demands a change from early, mid-or even later-century medicine. If Homer Smith was right in saying,'We are what we are because we have the kind of kidneys we have'and'The kidneys make the stuff of philosophy', then the who, what, where, when, and why the gray delta will be cared for must focus on the stuff of geriatric nephrology.

Overcome the toughest clinical challenges in nephrology with the new 9th edition of Brenner/Rector's The Kidney! A brand-new editorial team of Drs. Maarten W. Taal, Glenn M. Chertow, Philip A. Marsden, Karl Skorecki, Alan S. L. Yu, and Barry M. Brenner,, together with a diverse list of international contributors bring you the latest knowledge and best practices on every front in nephrology worldwide. Brand-new sections on Global Considerations in Nephrology and Pediatric Nephrology, as well as new chapters on recent clinical trials, cardiovascular and renal risk prediction in chronic kidney disease, identification of genetic causes of kidney disease, and many others, keep you at the forefront of this rapidly growing, ever-changing specialty. Brenner/Rector remains the go-to resource for practicing and training nephrologists and internists who wish to master basic science, pathophysiology, and clinical best practices.Broaden your knowledge base with expert, dependable, comprehensive answers for every stage of your career from the most comprehensive, definitive clinical reference in the field! Prepare for certification or recertification with a review of the basic science that underpins clinical nephrology as well as a comprehensive selection of the most important bibliographical sources in nephrology. Visually grasp and better understand critical information with the aid of over 700 full-color high-quality photographs as well as carefully chosen figures, algorithms, and tables to illustrate essential concepts, nuances of clinical presentation and technique, and decision making. Get internationally diverse, trusted guidance and perspectives from a team of well-respected global contributors, all of whom are at the top and the cutting edge of your field. A new editorial team headed by Dr. Taal and hand-picked by Dr. Brenner ensures the ongoing adherence to previous standards of excellence. Access information quickly thanks to a new, reorganized format and supplemental figures, tables, additional references, and expanded discussions. Keep current with the rapid development of care and research worldwide. A new section,'Global Considerations', focuses on regions outside Europe and North America. Leading experts from Latin America, Africa, Near and Middle East, Indian Subcontinent, Far East, Oceania and Australia present their expert insights into specific conditions, as well as progress and challenges in the development of the specialty. Improve therapy and outcomes for children with renal disease. New to this edition,'Pediatric Nephrology'addresses renal pathologies that usually present in childhood and covers topics such as Maturation of Kidney Structure and Function; Fluid; Electrolyte and Acid-Base Disorders in Children; Diseases of the Kidney and Urinary Tract in Children; Dialysis in Children; and Kidney Transplantation in Children. Stay up to date with all the latest clinical information including recent clinical trials, genetic causes of kidney disease, and cardiovascular and renal risk prediction in chronic kidney disease.

This new clinical resource brings you a state-of-the-art comprehensive review on every clinical condition encountered in pediatric nephrology in one concise, clinically focused text. International experts provide you with the latest on epidemiology, diagnosis, investigations, management, and prognosis for a full range of pediatric kidney disorders. A full-color, highly visual, meticulously crafted format, makes this material remarkably easy for you to access and apply. Comprehensive Pediatric Nephrology also serves as an ideal resource for board review study for the ABP subspecialty boards in pediatric nephrology.Just the right amount of'need-to-know'basic science coupled with practical clinical guidance for every disorder helps you make efficient, informed decisions.The book provides a much needed update on the genetic origins of pediatric kidney disorders.Chapters about glomerulonephritis, nephrotic syndrome, and tubular disorders provide an orientation in the pathophysiology, differential diagnosis, and treatment of these heterogeneous disease entities.Disease specific chapters include diagnostic work-up, laboratory evaluation, and management of disorders and complications, making this necessary information readily accessible. The prevention and management of pediatric chronic renal failure and its complications are comprehensively covered in many detailed chapters.Four chapters devoted to childhood hypertension offer you insights into an increasingly prevalent condition among pediatric patients so you can treat them more effectively.A chapter on the role of the interventional radiologist in pediatric nephrology keeps you apprised of the latest advances in a key area in the field.The function of complementary and alternative medicine in patients with renal disease is reviewed for the first time in a standard pediatric nephrology textbook.A consistent organization throughout and a full-color layout lets you find diagnostic guidance quickly.

Here's an in-depth, quick-reference, problem-solving resource for those involved in the care of dialysis patients. More than 120 world-class authorities discuss dialysis techniques, mechanical considerations, and complications related to various diseases for both pediatric and adult patients. Selected annotated references and excellent cross-referencing between chapters help you find answers fast, and more than 100 photos, drawings, charts, and tables, mostly in color, clarify complex topics. Providing practical, immediately useful guidelines that can be applied directly to patient care, this book is a'must-have'for all dialysis caregivers.Presents the practice-proven experience of top experts in the field of dialysis treatment.Offers dialysis guidance for both adult and pediatric patients in one convenient source.Features a readable hands-on approach, allowing you to quickly review the complicated concepts of dialysis.Includes helpful annotated bibliography lists in each section for further in-depth research on any subject.Explains complex dialysis concepts through abundant diagrams, photos, line drawings, and tables. Features a new 4-color format, enabling you to find the guidance you need more quickly.Includes coverage of convective dialytic therapies and the results of recent clinical trials.Ensures that you keep current on pediatric dialysis concerns prevention and treatment with new chapters including prevention and treatment of bone disease, management of anemia, assessing quality of life in pediatric patients undergoing dialysis, and immunizations in children undergoing dialysis.

The Nutrition and Health™ series of books have, as an overriding mission, to provide health professionals with texts that are considered essential because each includes: (1) a synthesis of the state of the science, (2) timely, in-depth reviews by the leading researchers in their respective fields, (3) extensive, up-to-date fully annotated reference lists, (4) a detailed index, (5) relevant tables and figures, (6) identi- cation of paradigm shifts and the consequences, (7) virtually no overlap of information between chapters, but targeted, inter-chapter referrals, (8) suggestions of areas for future research, and (9) balanced, data-driven answers to patient /health professional questions that are based upon the totality of evidence rather than the findings of any single study. The series volumes are not the outcome of a symposium. Rather, each editor has the potential to examine a chosen area with a broad perspective, both in subject matter as well as in the choice of chapter authors. The international perspective, especially with regard to public health initiatives, is emphasized where appropriate. The editors, whose trainings are both research and practice oriented, have the opportunity to develop a primary objective for their book, define the scope and focus, and then invite the leading authorities from around the world to be part of their initiative. The authors are encouraged to provide an overview of the field, discuss their own research, and relate the research findings to potential human health consequences.

Anemia in the elderly has been properly defined as the silent epidemic, representing 3 million people in the United States aged 65 years and older. Incidence and prevalence of this condition increase with age. It differs in its etiology, pathogenesis and treatment from anemia in children and younger adults. Anemia is associated with reduced survival, increased risk of functional dependence and hospitalization, increased risk of congestive heart failure and stage renal disease and cognitive disorders. Approximately 70% of anemia in older individuals is reversible.

Revised in line with feedback from users of the first edition, this practical clinical resource boasts a worldwide array of contributors, including the most prominent pediatric nephrologists in the US. Excellently illustrated with photomicrographs and clinical diagrams supporting the chapters, Clinical Pediatric Nephrology features expanded case histories relating to the discussion and management of renal disease – thus ensuring that this is a highly useful reference tool for nephrologists and house officers in practice, as well as nephrology fellows in training.

The best reference on end-stage renal disease! This authoritative resource has been thoroughly revised for physicians caring for the rapidly growing population of renal patients, in an expanding number of dialysis centers. Written by world-class experts, it provides coverage of essential new techniques in peritoneal dialysis, home dialysis, pediatric dialysis, and more.

In this timely publication, various topics related to ESRD are discussed, including vascular disease and atherosclerosis in uremia, outcomes of hemodialysis patients in different countries, malnutrition as well as oxidative stress and chronic inflammation as risk factors for cardiovascular disease. Moreover, the opportunity of using peritoneal dialysis as a first treatment modality for ESRD is debated, together with the benefits which may be achieved with daily dialysis. Further topics include the most advanced techniques for electrolyte monitoring and profiling in hemodialysis as well as the treatment of acute renal failure, describing the new acute dialysis quality initiative. Another important part of this publication is a controversy on whether hemoglobin levels in pre-ESRD and hemodialysis patients should be normalized or not, followed by a discussion of the potential long-term benefits of a new technology coupling hemoperfusion with hemodialysis, utilizing a new sorbent device. A definition of the real utility of these technologies in daily clinical practice and whether they are economically more affordable with present reimbursement policies rounds off the presentations. Being the second volume in this series (see also the volumes for the years 2000, 2002 and 2003), this book is intended to serve as a syllabus for conferences as well as an educational tool for fellows and residents. At the same time, it provides a most helpful update on recent practice and technology for all physicians involved in the field of hemodialysis.

Responding to the rising number of ESRD patients and the increasing importance of dialysis care and management, Complications of Dialysis provides a comprehensive, multidisciplinary perspective on the latest therapy options-addressing complications that may arise from dialysis and utilizing the patient-, technique-, and relationship-oriented approa

... About previous editions... `The standard reference book for the artificial kidney world.'JAMA `The aim of the authors - to produce a standard text for nephrologists and those with an interest in today's treatment of renal failure - is fully achieved.'Urological Research `A superb book... the detail and depth of discussions are unequalled in any current nephrology text.'Mayo Clinic Proceedings.