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Revised by a collaborative, international, interdisciplinary team of editors and authors, this edition of the Manual of Clinical Microbiology includes the latest applications of genomics and proteomics and is filled with current findings regarding infectious agents, leading-edge diagnostic methods, laboratory practices, and safety guidelines. This edition also features four new chapters: Diagnostic Stewardship in Clinical Microbiology; Salmonella; Escherichia and Shigella; and Morganellaceae, Erwiniaceae, Hafniaceae, and Selected Enterobacterales. This seminal reference of microbiology continues to set the standard for state-of-the-science laboratory practice as the most authoritative reference in the field of microbiology. If you are looking for online access to the latest from this reference or site access for your lab, please visit www.wiley.com/learn/clinmicronow.

The shift of weather patterns has affected the incidence and prevalence of infectious diseases, including mycoses. Mycoses have remained neglected due to a lack of training and recognition within the medical community. Nonetheless, these diseases remain common worldwide while frequently being underdiagnosed. Climate change affects the distribution of fungal communities, provoking outbreaks in locations where these mycoses were absent or in low frequencies. Moreover, the reports of clinical cases related to new fungal pathogens have increased due to the description of new fungal species or due to the ability of some species to shift to new hosts. Thus, this book, The Impact of Climate Change on Fungal Diseases, is a contribution to the knowledge of a global environmental phenomenon and its relation to these diseases, and it serves as a guide for health professionals to dive deep into the repercussions of climate changeand how they can implement measures for the prevention and control of fungal infections.

This fourth edition of the Textbook consists of Eight Sections, divided into 39 Chapters, which cover the entire spectrum of fungal infections, spanning from superficial to opportunistic infection along with the latest information on therapeutic modalities. The pseudofungal infections, mimicking typical fungal diseases, are also given in a separate Section. The Textbook encompasses interesting historical aspects pertaining to Medical Mycology and has valuable references for further reading by the students. It contains a very useful introductory chapter on the basics of medical mycology. The last Section has seven Appendices, pertaining to various procedural details mentioned in the text of the Book. One of them is exclusively devoted to the antifungal susceptibility testing.

Superantigens constitute a growing family of bacterial and viral proteins that share the capacity of inducing massive activation of the immune system. This volume contains contributions from leaders in the field of classical T cell superantigens and sheds light on relevant B cell superantigens at the molecular and biochemical levels. Moreover, articles in this publication deal with the emerging, intriguing possibility that immunoglobulin superantigens can activate primary effector cells of allergic disorders both in vitro and in vivo, thus acting as superallergens. A detailed account is also given of the biochemical, immunological and clinical characteristics of several endogenous, viral and bacterial superallergens, which are probably relevant in a variety of human diseases. This is the first volume to put together basic and clinical aspects of the classical T cell superantigens, B cell superantigens and superallergens. It will therefore be indispensable reading to basic and clinical immunologists, microbiologists, virologists and specialists in allergic and immune disorders.