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Dissemination of knowledge is the best and only strategy capable of improving clinical management in rare and ultra-rare malignancies, including primary adrenal malignancies. It is preliminary to any further healthcare policy such as, for example, the centralization of cases in referral institutions. Adrenal primary malignancies are probably the rarest among rare pathologies. This epidemiological consideration is at the origin of a vicious circle: the lack of preoperative diagnosis leads to inappropriate surgical procedures and to inadequate follow-up and systemic therapy strategies. Furthermore, when malignancy is recognized, the relative role of systemic, surgical, or other local ablative techniques is often misinterpreted. All this produces a negative impact on survival, also in patients who could have been cured with a correct therapeutic strategy. This open access book provides a user-friendly exploration of these rare conditions, using a transversal approach common in modern precision medicine. The text covers various clinical aspects, including epidemiology, genetics, molecular medicine, imaging, and surgery. Guidelines for managing syndromic situations are provided. The book thoroughly addresses all the different surgical issues and emphasizes the importance of pathology in assessing prognosis. The pivotal role of medical oncologists in managing these patients is explored, along with alternative treatments such as nuclear medicine and radiotherapy. Finally, the book highlights the latest preclinical research and its implications for translational medicine.

The second edition of this important textbook covers all aspects of neuroendocrine tumors (NETs), from epidemiology, pathological classification and evaluation, and molecular biology through to diagnostic imaging methods and therapeutic options, including the latest targeted therapies and immunotherapies. Readers will find individual discussion of each of the various types of NET: gastrointestinal, lung, and pancreatic tumors such as insulinomas, gastrinomas, glucagonomas, VIPomas, somatostatinomas, PPomas, and non-functioning pancreatic NETs, as well as medullary thyroid carcinomas, pheochromocytomas, paragangliomas, etc. In addition to NETs, endocrine tumors such as thyroid tumors and adrenocortical tumors are also covered. The contributing authors are internationally recognized experts who bring a wealth of science and experience to the subject. This book will be an invaluable source of information for practicing medical oncologists, surgeons, endocrinologists, gastroenterologists, and pathologists as well as for trainees in these fields.

The Tata Memorial Centre Textbook of Oncology is an authoritative and comprehensive book, meticulously compiled to cover contemporary issues in oncology. It features contributions from 189 authors, culminating in 76 chapters. Authored by faculty members from the renowned Tata Memorial Centre, this textbook offers a harmonious blend of detailed information and practical approaches. It serves as a comprehensive resource that contextualizes the practice of oncology in TMC and offers insights into delivering high-quality cancer care in diverse settings. It offers an authentic overview of the TMC approach to multidisciplinary cancer care. The Textbook is designed to cater to a wide array of readers – from undergraduate medical students to postgraduates specializing in general surgery, general medicine, pediatrics, gynecology, radiation oncology, and other disciplines, and practicing community oncologists. A notable feature of the Textbook is its utility in preparing students for entrance and exit examinations. This book is an essential resource for established cancer specialists, including surgeons, medical oncologists, radiation oncologists, and those in allied fields. It is also invaluable for super-specialty students and postgraduates with an interest in cancer management, offering a comprehensive guide to the dynamic field of oncology.

Comprehensive and case-based, Pediatric Fluid, Electrolyte, and Acid-Base Disorders provides a state-of-the-art overview of this complex field in a concise, authoritative format perfect for self-study or review. Real-life patient cases reflect those that are frequently encountered in clinical decision making. These narrative case studies offer a unique opportunity for readers to determine how best to diagnose, treat, and manage their patients based on the history of present illness, review of symptoms, relevant history, and physical examination findings. - Includes over 200 cases frequently seen by medical students, residents, practicing physicians, and other health care provides during routine daily clinical practice. - Presents cases in a consistent template including succinct summary of patient's history, signs and symptoms, examination, and initial diagnosis/treatment plan. - Follows each case with questions and answers that provide a detailed discussion on each topic, with further cross-references and direction where appropriate. - An ideal resource for students, residents, and fellows rotating on nephrology subspecialty services, as well as for practicing physicians who need quick access to current scientific and clinical information on managing fluid, electrolyte, and acid-base disorders in children.

This book covers all aspects of how various Hormonal diseases affect Skin Health. It covers essential parts of the most common Hormonal disease - Polycystic Ovarian Disease (PCOD), i.e., its Pathogenesis, investigations, and individual clinical features with their Line of management.Chapters also provide information about other common yet less discussed hormonal issues like- Diabetes, Thyroid disease, and obesity affecting the skin and what signs and symptoms should be looked for in such patients for early diagnosis and treatment.Hence, this book assists Dermatologists, Consulting Physicians, Post Graduates, and Interns in a holistic understanding and practical management of standards as well as other miscellaneous issues like Diet and Hormones and Urticaria and Hormones.

Preserving good skin condition has significant quality of life implications for diabetic patients, especially for those suffering from related ulcers or diabetic foot syndrome. This timely work on the cutaneous manifestations of diabetes offers an interdisciplinary approach to help the practitioner's differential diagnosis and choice of the best therapeutic options. Starting from the broader picture to focus successively on infections of the skin, problems resulting from reduced circulation, leg ulcers, it also includes parts on wound and skin care. Chapter topics include complications and imaging, dermatoses and (auto) inflammatory skin diseases. Richly illustrated and presented in a clear style, Cutaneous Manifestations in the Diabetic Patient is meant for clinical dermatologists, general practitioners, internal medicine practitioners but will be a valued companion to nursing personnel and health care professionals involved in the care of diabetic patients, enabling early detection and safe management.

This practical, pocket-sized guide presents everything that a medical student needs to know to master the biochemistry and human metabolism content for the USMLE Step 1. It is a clear concise review of these topics in an easy to understand and digestible format. Each of the five sections provides high-yield information on the essentials of carbohydrate, lipid, protein, nucleotide and vitamin metabolism, respectively, including diagrammatic figures and tables for at-a-glance referral.

Diabetic complications, which occur both acutely and on a chronic basis, are an enormous challenge facing doctors at every level of care.There needs to be more knowledge, which is compiled into a textbook and is unavailable for reference- taking this into account, to provide clinical care, to address challenges to family physicians, nurses, diabetologists, subspecialty physicians, surgeons, doctors in training, and telemedicine consultations. This book is a compilation of different subjects in diabetic care, which can be easily referred to in diverse situations and organ involvement for appropriate management strategies. This book covers not only common complications lucidly but rare complications with a structured management plan. The book contains up-to-date information with color / black & white figures to explain the disease process and follow-up plans. The book is good teaching material for medical students, interns, nurses, and junior-level doctors and consultants. Chapters will provide a simple, comprehensive complication assessment with essential highlights—for example, foot ulcers and skin infections with management strategies for day-to-day evaluation. It covers any disease process with skin and mucus membrane involvement with serious issues such as Stroke, Myocardial Infarction, and CKD.

The fourth edition of this compilation has seen qualitative improvements over the previous editions has been aligned to the new CBME curriculum. While the contents of the book are comprehensive, presentation is simple. Clinical images, tables, boxes, algorithms and diagrams are simple and enhance the learning. This book will definitely be an essential learning tool for students of internal medicine.

Pediatric Endocrinology covers all of the main aspects of translational endocrinology and clinical practice, making it an ideal resource for both paediatricians and endocrinologists. The book emphasizes the newer translational aspects of the topics covered, as well as molecular advances in diagnosis and therapy, although clinical relevance, with a particular focus on evidence-based clinical management, remains paramount. Further, transitions from childhood to adolescence and adulthood are discussed wherever appropriate. Written by a combination of respected and emerging experts in the field, this book is intended to serve as a major reference work for pediatric endocrinologists at all stages of their careers, as well as general pediatricians with an interest in endocrinology and diabetes, and endocrinologists in adult practice who may also treat children and adolescents. The book is part of the SpringerReference program, which provides access to ‘living editions'thatare constantly updated using a dynamic peer-review publishing process.

•Tables, electrocardiographs, and up-to-date investigations have been included. •Updated information on both diagnosis and treatment of maladies, both common and some uncommon. •A very useful book for going through examinations as well as to have an in-depth knowledge of the subject of Medicine. •New concept of “Box” has been introduced which gives important information of the subject matter at a glance. •Illustrations have been used in pathogenesis and diagnosis of diseases.

In this book, a clinician can experience the most typical medical subjects in a primary care setting, which is the highlight. The book brings knowledge and counseling skills into action as it takes you through various scenarios. In addition, it serves as a guide for passing the Objective Structured Clinical Examination, or'OSCE,'by mirroring the Middle East and Arab World exam format in a structured fashion. With that, the book left behind distinctive traces that productively revealed its value and reputation.The book chapters provide a systematic approach to patient-centered medical problems, making it easier and handier for the students. The process covers in-depth history remarks, an organized set of physical examinations, and careful counseling tips.

It is my privilege and honor to introduce the seventh edition of Manual of Practical Medicine. The basic principles involved in clinical examination have not changed. All the chapters have been revised and updated.

This book provides an overview of endocrine diseases associated with alterations of salt metabolism, with a focus on clinical and pathophysiological aspects. It covers various topics in the endocrine control of salt and water homeostasis, such as neuroendocrine determinants of water balance, adrenal hormone biosynthesis, hormonal function in target renal cells, and dysfunction of hormonal target effectors in the kidney. It also features an update on the clinical management of these diseases, including new diagnostic and therapeutic tools. Written by a combination of recognized and emerging experts in the field, this book is intended as a major reference work, not only for endocrinologists and nephrologists, but also for pediatricians, neonatologists, cardiologists, and emergency medicine and intensive care specialists, who can be faced with the management of endocrine diseases responsible of salt and water imbalance. The book is part of the SpringerReference program, which provides access to ‘living editions'that are constantly updated using a dynamic, peer-review publishing process.

Part of the renowned Braunwald family of references, Hypertension: A Companion to Braunwald's Heart Disease provides today's clinicians with clear, authoritative guidance on every aspect of managing and treating patients who suffer from hypertensive disorders. An invaluable resource for cardiologists, endocrinologists, and nephrologists, this one-stop reference covers all the latest developments from basic science to clinical trials and guidelines related to the treatment of common to complex hypertension. Now fully updated from cover to cover, the 4th Edition offers unparalleled coverage of hypertension in an accessible and user-friendly manner. - Thoroughly covers new treatment guidelines related to recent research and the latest physiologic understanding for a wide range of patients with hypertension and related co-morbidities. - Includes new chapters on Hypertension in Women, Mineralocorticoid Receptor Antagonists, Exercise and Hypertension, and Telemedicine/Digital Health. - Contains new or expanded content on epidemiology, pathophysiology, immunology, clinical findings, laboratory testing, invasive and non-invasive testing, risk stratification, clinical decision-making, prognosis, and management. - Provides new chapter summaries and a new focus on clinical and actionable content using a streamlined, narrative format. - Covers behavior management and prevention as an integral part of hypertensive and pre-hypertensive treatment plans. - Highlights combination drug therapies and management of chronic complications of hypertension. - Offers expert guidance from worldwide experts in cardiology, endocrinology, and nephrology, and integrates the most recent guidelines from leading organizations around the world. - Any additional digital ancillary content may publish up to 6 weeks following the publication date.

This book aims to gather the current knowledge regarding different aspects of brain and spinal cord tumors in order to more efficiently help the patients. Brain tumors comprise about 5–9% of all human neoplasms; and the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. The more we know about the nature and characteristic of brain and spinal cord tumors, the more precise decision could be made for each patient, in order to reach the best outcome. While surgical resection, chemotherapy, and radiotherapy have been considered as the standards of care for benign and/or malignant CNS tumors since a long time ago, new therapeutic approaches such as immunotherapy have been recently proposed to be considered for treatment of CNS tumors, especially as in some cases, the tumors might be inoperable or the patient may not benefit from other treatment modalities after several recurrences. The second volume of the book focuses on clinical aspects of these tumors. Accordingly, the most important brain and spinal cord tumors are specifically discussed in each chapter based on a rational outlining for all chapter in this volume: Background and epidemiology, genetics, immunology and molecular biology, histopathology and morphology, imaging and radiologic features, clinical manifestations, therapeutic approaches, surgical intervention, chemotherapy and radiotherapy, new therapeutic modalities, follow-up, and prognosis. The chapters of this volume discuss the following pathologies of brain and spinal cord tumors: malignant glioma, benign glioma, meningiomas and other meningeal tumors, ependymomas, medulloblastomas, pineal tumors, choroid plexus and ventricular tumors, neuroectodermal tumors of CNS, neuroepithelial tumors of CNS, pituitary gland tumors, craniopharyngioma, schwannomas and nerve-sheet tumors, hemangioblastomas and other vascular originating tumors, brain and spinal tumors of embryonic origin, germ line cell tumors, malignant bone or cartilage-originating tumors of brain and spine, benign bone or cartilage-originating tumors of brain and spine, brain tumors affecting the orbit globe and orbit tumors affecting the brain, CNS lymphomas, metastatic lesions of the brain and spine, malignant spinal tumors, benign spinal tumors, brain and/or spinal cord tumors accompanied with other diseases or syndromes, psychological and psychiatric aspects of brain and spinal cord tumors, a brief explanation on surgical approaches for treatment of different brain tumors. This volume of book is useful for physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists, and neuroradiologists.

The Diabetes Textbook: Clinical Principles, Patient Management and Public Health Issues (2nd Edition) addresses diabetes from a comprehensive, multidisciplinary perspective. Its purpose is to integrate state-of-the-art information on diabetes from specialists in various disciplines, including epidemiology, public health, pathophysiology, non-pharmacologic and pharmacologic treatment, patient support, acute and chronic complications, new and unproven therapies, and prevention. The main benefit of “The Diabetes Textbook” is its integrative approach. The book is therefore intended for three main types of readers: 1) physicians and health professionals seeking a comprehensive approach to diabetes; 2) those with previous expertise in a specific professional area who want to expand their knowledge; and 3) those interested in learning about topics not previously covered, who will find the contents of “The Diabetes Textbook” both enriching and innovative. The Diabetes Textbook is intended for a broad readership, including professors of medicine and related disciplines (nursing, nutrition, psychology); general physicians; internists and specialists, e.g. in ophthalmology, endocrinology, cardiology, obstetrics and gynecology, pediatrics, geriatrics, epidemiology and public health. To address these readers'needs, the second edition is divided into the following eleven sections: 1) Magnitude of the Problem from an Individual and Social Context, 2) Diagnosis, Classification and Mechanisms of Disease, 3) Global Experiences in Diabetes Care, 4) Basic Components of Management: Patient-Centeredness, Evidence-Based Medicine, and Outcomes, 5) Resources of Support for Persons with Diabetes, 6) Drug Therapy, 7) Cardiovascular Risk Factors, 8) Acute Complications, 9) Chronic Complications, 10) Diabetes in Special Populations, and 11) Novel Therapeutic Approaches: Evidence-Based and Non-Proven, and Diabetes Prevention.

Das Standardwerk der Andrologie - jetzt komplett aktualisiert! Das Buch gibt einen vollständigen, interdisziplinären Überblick aller Themen der Andrologie, u.a. · der Infertilität, · des Hypogonadismus, · der männlichen Kontrazeption, · der erektilen Dysfunktion und · der Varianten der sexuellen Differenzierung. Der Leser erhält detaillierte Informationen über · die Physiologie der Hoden- und Spermienfunktion · die Diagnostik und Therapie einschl. operativer Verfahren in der Andrologie · die klinische Praxis der Paarbehandlung, · relevante Fakten aus der Gynäkologie, · moderne Verfahren der assistierten Fertilisation · psychologische Faktoren der Sexualität und Infertilität · Umwelteinflüsse auf die Fertilität · Therapie mit Testosteron und Missbrauch · endokrinologische und reproduktive Funktionen des alternden Mannes. · Fertilitätsprotektion · rechtliche und ethische Grundlagen der Andrologie Zusätzlich werden die relevanten naturwissenschaftlichen Grundlagen – einschließlich Molekularbiologie und -genetik – abgedeckt. Komplett nach dem neuesten Stand der wissenschaftlichen Erkenntnis überarbeitet, aktualisiert und praxisorientiert ist der Nieschlag das Standardwerk der Andrologie, an dem keine Ärztin und kein Arzt, der sich mit dem Thema befasst, vorbeikommt. Für Andrologen und Teilnehmer der Zusatzbezeichnung'Andrologie', Urologen, Dermatologen und Internisten, die sich mit dem Gebiet Andrologie beschäftigen. Für Reproduktionsbiologen und Reproduktionsmediziner mit Interesse an der Paarbehandlung.

Practical and highly organized, the 5-Minute Clinical Consult 2024 provides rapid access to the diagnosis, treatment, medications, follow-up, and associated conditions for more than 500 disease and condition topics to help you make accurate decisions at the point of care. Organized alphabetically by diagnosis, it presents brief, bulleted points in a templated format, and contains more than 100 diagnostic and therapeutic algorithms. This up-to-date, bestselling reference delivers maximum clinical confidence as efficiently as possible, allowing you to focus your valuable time on providing high-quality care to your patients.

Focusing on the essential information you need to know for the most commonly encountered problems in outpatient internal medicine, this practical volume in the Washington Manual® series provides concise, high-yield content that reflects today's advances in patient evaluation and management. In one convenient, portable resource, you'll find complete coverage of everything from hypertension and diabetes to sleep disorders, nutrition, and care of the cancer patient—all at your fingertips for quick review and reference. Edited by Drs. Maureen D. Lyons, Peter J. McDonnell, and Jennifer M. Schmidt, The Washington Manual® of Outpatient Internal Medicine, 3rd Edition, is an excellent companion to the Washington Manual® of Medical Therapeutics, which thoroughly covers inpatient care.

This completely updated 4th edition now includes two volumes: it retains the easy-to-use handbook format of the previous successful book, while fulfilling the need for a review of the content. Taking into consideration recent advances in systemic and topical treatments, state-of-the-art lasers, and the latest evidence-based recommendations, it now includes biologic agents for psoriasis and their use as off-label treatments in other skin disorders, targeted agents for malignant melanoma and basal cell carcinoma, and new treatment modalities for rosacea, acne, atopic dermatitis, and urticaria, to name but a few. The European Handbook of Dermatological Treatments provides concise, up-to-date overviews of treatment guidelines and clinical pearls for a large number of skin diseases. It is divided into three main sections addressing the many different skin diseases, the drugs available for dermatological treatments, and the various methods applied in dermatology, including fillers, botulinum toxin, lasers, dermoscopy, cryosurgery, and electrosurgery. Written by a recognized expert in the field, each chapter focuses on a particular skin disease, illustrating current treatments while providing a brief synopsis of the etiology and clinical presentation of the disease. Treatment indications and contraindications, modes of action, and dosages are clearly identified and the content is enhanced by a wealth of clinical pictures and tables, making it an engaging tool for professionals, and a valuable learning resource for young practitioners, as well as postgraduate students and residents.

The purpose of this book is to outline the topics that are critical in the dermatological approach to patients with cancer. This purpose will be accomplished by discussing the value of a multidisciplinary approach, and case examples will be used, including some from the Hospital Sírio-Libanês, a pioneering institution in the treatment of cancer. In all, the book will present and discuss the best global evidence for the dermatologic care of patients with cancer, skin cancer, and solid organ- and bone-marrow-transplanted patients. The clinical, surgical, pathologic, imaging, radiotherapy, oncology and palliative care aspects of the dermatologic care of cancer patients will be covered. The book will also discuss subjects such as genetics, biology, evidence-based medicine, and new diagnostic methods and tools such as dermoscopy and confocal microscopy. Chapters will be based on the following key areas: educating clinicians on how to prevent skin cancer in patients, screening and counseling, diagnosis and treatment of pigmented lesions, melanoma and nonmelanoma skin cancer, cutaneous lymphomas, sarcomas, leukemic and lymphomatous infiltrations, cutaneous metastases, cutaneous paraneoplasic manifestations and cutaneous adverse reactions to chemotherapy and radiation treatment. The primary audiences are dermatologists, oncologists, radioncologists and oncologic surgeons. The secondary audience is residents in these fields. The goal is to prepare and update all specialists on this important clinical and research area.

This very well-received book, now in its third edition, equips the radiologist with the information needed in order to diagnose internal medicine disorders and their complications from the radiological perspective. It offers an easy-to-consult tool that documents the most common and most important radiological signs of a wide range of diseases, across diverse specialties, with the aid of an excellent gallery of images and illustrations. Compared with the second edition, new updates have been added, including three new chapters that cover autonomic medicine, psychosomatic medicine, and forensic medicine. Internal Medicine – An Illustrated Radiological Guide puts the radiologist in the internal medicine physician's shoes. It teaches radiologists how to think in terms of disease progression and complications, explains where to look for and to image these complications, and identifies the best modalities for reaching a diagnosis. It will also benefit internal medicine physicians by clarifying the help that radiology can offer them and assisting in the choice of investigation for diagnostic confirmation.

Fully revised for this fourth edition, the Oxford Handbook of Obstetrics and Gynaecology fully reflects new developments in the field. Featuring new sections on the outcomes of the MBRRACE report, abnormally adherent and invasive placenta, pregnancies in mothers of advanced age, assisted reproduction, and ovarian cancer screening, it provides a contemporary overview of this complex and important specialty. Written and reviewed by a team of highly experienced clinicians, academics, and trainees, this Handbook is a perfect starting point for preparation for postgraduate exams. Practical advice is presented with key evidence-based guidelines, supported by visual algorithms and top clinical tips. The previous edition was Highly Commended in the Obstetrics and Gynaecology category of the BMA Book Awards. The indispensable, concise, and practical guide to all aspects of obstetric and gynaecological medical care, diagnosis, and management, this fourth edition continues to be the must-have resource for all specialist trainees, junior doctors, and students, as well as a valuable aide memoire for experienced clinicians.

Pediatric Surgery provides an authoritative, up-to-date and comprehensive analysis of current practice in the field. It is divided into three topical volumes, with a total of seven sections focusing on general principles, newborn surgery, general pediatric surgery, tumor surgery, trauma, transplantation, and pediatric urology surgery. Detailed descriptions of surgical techniques and pre- and postoperative management are provided by experts from various parts of the world.The result is an international reference on the surgical management of both common and rare diseases of infants and children that will be an ideal source of information and guidance for pediatric surgeons, pediatric urologists, neonatologists, pediatricians, and all those seeking more detailed information on surgical conditions in children. The three topical volumes are as follows:General Principles and Newborn SurgeryGeneral Pediatric Surgery, Tumors, Trauma andTransplantationPediatric Urology

This book describes how exposure to various classes of endocrine disruptors, as well as other environmental chemicals targeting the endocrine system by alternative non-endocrine mechanisms, impact on endocrinological and endocrinological-related diseases. It includes comprehensive reviews of all aspects of environmental endocrinology, ranging from sources and patterns of exposure and identification of endocrine targets to direct endocrine disruptive mechanisms and indirect actions on the endocrine system, the latter including endocrine cell-directed cytotoxicity, oxidative damage, and genetic and epigenetic aberrations resulting in endocrine damage. It also examines the causal pathways and offers an extensive overview of downstream endocrinological and endocrinological-related disorders. In addition, several chapters focus on transgenerational actions, which are a topic of particular interest. Lastly, evidence from preclinical and clinical studies provides the basis for an in-depth, critical discussion of each topic. The book is part of the SpringerReference program, which provides access to ‘living editions'that are constantly updated using a dynamic peer-review publishing process.

The extensively revised third edition of this text offers an in-depth practical guide to clinical conditions encountered in pediatric nephrology. Extensively updated disease-specific chapters offer detailed coverage of relevant basic science, diagnostic work-up, laboratory evaluation methods, appropriate management options and potential complications. Topics covered include disorders of renal development, glomerular disorders, the kidney and systemic disease, renal tubular disorders, tubulointerstitial disease, urinary tract disorders, acute kidney injury, chronic kidney disease, dialysis, kidney transplantation and hypertension. Information is also provided on important related issues, including the genetic origins of diseases, the role of complement in the pathogenesis of kidney disease, and pharmacological aspects related to the kidney. Pediatric Kidney Disease comprehensively reviews a range of clinical conditions encountered in pediatric nephrology, assisting the reader to develop their skills and improve their clinical decision-making. It is a vital resource for trainees and practicing clinicians alike and a useful reference for those preparing for pediatric nephrology board examinations.

Every surgical subspecialty has been rapidly developing with establishment of the board certification. The Division of Endocrine Surgery (DES) of the European Board of Surgery has defined the curriculum for Endocrine Surgery to include thyroid, parathyroid, adrenal and GEP-NET surgery, and handles accreditation in Endocrine Surgery. The first examinations in Endocrine Surgery in Europe have been introduced in 2003. The main goal of the exam is to maintain a uniform and high standard of endocrine surgical professionalism across the Europe.This book was completed with the expectation that it would benefit all European surgeons looking to be certified in Endocrine Surgery. Additionally, surgeons from the United States and other non-EU countries we hope will also benefit from this book. There is a need for a specialized book that reviews evidence based endocrine surgery that aligns itself with current curriculum standards in the field. The book contains knowledge that is expected to be known on the board examination of the DES. In general, chapters start with a patient's case followed by questions. The subsequent comprehensive yet concise main text provides all the information needed for a successful DES exam and cites important references. After the patient case and questions, the text goes on to define the condition, the standard of care approach to establish the diagnosis, perform diagnostic tests of choice, review evidence-based treatment options including medical therapy, preparation for surgery. The chapters conclude with follow up care and long term outcomes. The topics discussed within this book closely follow the curriculum of the European Board of Surgery Examination.Written by experts in the field, Endocrine Surgery Comprehensive Board Exam Guide is a valuable source of preparation for the Endocrine Surgery examination and brings Endocrine Surgery to a higher level of expertise byhelping to raise the standard of training for future endocrine surgeons.

Since the publication of the 7th edition of this book, there has been a remarkable increase in information in several clinical areas, including cardiology, immunology and oncology. This rapid knowledge expansion has led to practice changes for family physicians and other primary care providers. Patients are now discharged from tertiary care hospitals to their home communities with life sustaining left ventricular assist “heart pumps”. Hepatitis C, once an incurable illness, is now routinely cured. Oncology treatment regimens are increasingly becoming ambulatory and individualized. The decreased cost and increasing availability of health monitoring devices will make it possible for physicians to remotely check on the health status of their patients in their homes. With the ongoing and worsening shortage of family physicians across the US, the practice model for family medicine in the future may tend toward a family physician supervising a cast of mid-level providers as they care for a panel of patients, versus the physician providing the majority of care. All of these changes will require practice pattern changes and a need for up to date sources of information for the family physician. In addition, the “family” of family medicine academic organizations is undertaking a major review of the practice, training, funding and evaluation of all aspects of family medicine. Eight family medicine organizations have launched the “Family Medicine for America's Health” (FMAHealth) with the expressed purpose “to strategically align work to improve practice models, payment, technology, workforce and education, and research to support the triple aim”. This project has moved past the study phase and will soon move to the implementation phased. This book is organized into short, focused chapters almost exclusively dedicated to topics relevant to daily practice. All lead authors are themselves accomplished family physicianswho can specifically address the needs, concerns, and interests of this crucial profession. As one of the key reference textbooks for family medicine, it is very important to provide the most up-to-date knowledge to support learners and practitioners of family medicine in the face of rapidly expanding clinical knowledge and the extensive self-examination of family medicine. Family Medicine: Principles and Practice, 8th Edition, is a must-have reference for medical students, residents, practicing physicians, nurse practitioners and physician assistants with an active role in patient care.

The book offers a comprehensive overview of ENT diseases during pregnancy, postpartum and lactating period. It brings together the experience of authors from more than 25 countries and aims to provide a broader understanding of the diagnosis, prevention and treatment of the ENT pathologies in pregnant and lactating women. The book is organized in 7 main parts according to the ENT subspecialties, and each chapter features a reader-friendly, uniform structure. It includes developments about COVID-19 infection. ENT Diseases: Diagnosis and Treatment during Pregnancy and Lactation will appeal to a wide readership, from ENT practitioners through allergists and pulmonologists, to trainees and students in ENT, obstetrics/gynecology.​

This book provides a review of the most recent data on osteoporosis and bone health, presenting a vision of diagnosis and management for the year 2021 and beyond. It covers all pertinent aspects of bone health including diagnosis, fracture prevention, optimized practice, impaired orthostasis, and falls. The book examines recent developments in therapeutics, including goal-directed therapy, individualizing therapy, sequential and combined therapies, pharmaceuticals, and anabolic vs. antiresorptive therapy. In addition, it provides an in-depth overview of osteoporosis and bone health in complex patients, covering Duchene dystrophy, renal failure, periodontal diseases, and steroid-induced osteoporosis as well as considerations for pediatric populations and men. New Horizons in Osteoporosis Management is an essential resource for physicians and related professionals, residents, fellows, graduate students and nurses in rheumatology, endocrinology, radiology, pediatrics, primary care, and internal medicine.

Clinically-orientated and focused squarely on the core curriculum, Medicine for Finals and Beyond delivers what medical students need to know in a manner that encourages learning and recall. The consistent, easy-to-navigate structure makes locating information simple and is tailored for exam success. Highly illustrated throughout, notes based information is supplemented by'At A Glance textboxes', ‘Emergency Presentations'and ‘Must Know Checklists'for quick reference, while online question and answer material allows for self-testing during that inevitable last-minute revision.Key features:· Comprehensive - everything you need to know to pass your medical finals in a single volume· Accessible - systems-based chapters all follow a common structure· Convenient - summarises the ideal approach to the patient, including history and examination, clinical presentations, differential diagnosis and investigations· Focused - covers all the common conditions that medical students need to know for future practice· Relevant - designed with input from lecturers and studentsThis brand-new revision aid for medical students will be a convenient companion throughout clinical studies and an ideal aide-memoire for those approaching their final examinations.

This encyclopedia volume covers the complete field of endocrine pathology – from Acidophil Stem Cell Adenoma to Waterhouse-Friderichsen syndrome. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need.

•Comprises of latest research in the field of infertility. •It includes everything from basic knowledge of female and male fertility, investigations, and conventional treatments to the most advanced ART techniques. •Clear-cut messages on Do's and Don'ts based on evidences. •Practical approach with scientifically based explanations and to-the-point information is the highlight of this book. •The book will prove to be an ‘‘under the desk, immediate reference book''for every infertility consultant.

Known for its concise, easy-to-read writing style and comprehensive coverage, Cecil Essentials of Medicine has been a favorite of students, residents, and instructors through nine outstanding editions. This revised 10th Edition continues the tradition of excellence with a focus on high-yield core knowledge of key importance to anyone entering or established in the field of internal medicine. Fully revised and updated by editors Edward J. Wing and Fred J. Schiffman, along with other leading teachers and experts in the field, Cecil Essentials remains clinically focused and solidly grounded in basic science. - New focus on high-yield, core knowledge necessary for clerkships or residencies in medicine, with concise, complete coverage of the core principles of medicine and how they apply to patient care. - Each section describes key physiology and biochemistry, followed by comprehensive accounts of the diseases of the organ system or field covered in the chapters. - Full-color design enhances readability and retention of concepts, while numerous imaging videos cover cardiovascular disease, endoscopy, sphincterotomy, and more. - Superb images and photographs vividly illustrate the appearance and clinical features of disease. - New chapters cover Women's Cancer and Transitions in Care from Children to Adults with Pulmonary Disease.

Adrenal disorders are often difficult to diagnose due to common symptoms, and challenging to treat due to common comorbidities. Adrenal Disorders: 100 Cases from the Adrenal Clinic provides a comprehensive, case-based approach to the evaluation and treatment of both common and uncommon adrenal disorders, offering practical, real-world guidance highlighted by ultrasound scans, biopsy images, and tables. - Features 100 two-page cases covering a wide range of common and uncommon adrenal disorders. - Includes case report, investigations, treatment, and outcome for each case, plus a case overview with expert advice, take-home points, and references. - Organizes comprehensive content by type of disorder, including adrenal masses (benign and malignant), primary aldosteronism, ACTH-independent Cushing syndrome, ACTH-dependent Cushing syndrome, adrenal carcinoma, pheochromocytoma, adrenal and ovarian hyperandrogenism, and adrenal disorders in pregnancy. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Now in its third edition, Oncology Board Review: Blueprint Study Guide and Q&A is designed to help you prepare for the American Board of Internal Medicine (ABIM) Medical Oncology Certification Exam. This comprehensive digital resource has been revised to include new treatment regimens, clinical guidelines, and other advancements impacting the field as well as updated board-style Q&A. Dedicated sections cover hematological malignancies and solid tumors with a templated chapter approach highlighting epidemiology, etiology and risk factors, diagnostic criteria, staging, signs and symptoms of the disease, prognostic factors, indications for treatment, and special considerations. Later sections address other topics found on the exam, including cancer genetics and tumor biology, supportive and palliative care, bone marrow transplantation, and biostatistics. With more than 240 practice questions and detailed rationales, Oncology Board Review gives you the tools to study your way and the confidence to pass the first time! Key Features: Aligns with the latest ABIM Medical Oncology Certification Exam blueprint Provides a comprehensive yet concise review of all hematologic malignancies and solid tumors Covers anticancer therapies, clinical research methodology, survivorship and palliative care, and more areas found on the exam Revised to include new treatment recommendations and FDA approvals Includes end-of-chapter assessment questions with detailed rationales - a total of more than 240 questions throughout

The API Textbook of Medicine was first published in 1969. For more than 50 years, the Association of Physicians of India (API) has been regularly publishing the Textbook which is read by the medical students of our country. The current edition is up-to-date, reader-friendly and a realistic textbook, authoritatively written by experts with immense knowledge and experience, making it an ideal reference tool for Clinicians, Practitioners, and Students. The theme of the book from bedside to the bench to clinical management of cases—is well elucidated. The style and layout of the book is similar to that of the earlier editions. The contents of the book have been modified as per the latest advances and made as contemporary as possible.

The emphasis in this book is on providing evidence-based basic understanding of the subject. The pathophysiology of diseases has been simplified. Modes of presentation and approach to investigations are given in a clinically applicable manner. Therapeutic plan, as given in guidelines, is summarized and presented in a way it has to be used in practice. Each chapter has been written by an expert in the field. Language is simple to comprehend. Enriched with graphs and tables for easy understanding. Effects of COVID-19 on various systems have been included. Provides an Indian perspective of the diseases in each chapter. Includes MCQs in the chapters for revision. Selected readings can be used for more information on the topic.

Practical and highly organized, The5-Minute Clinical Consult 2023 provides rapid access to the diagnosis, treatment, medications, follow-up, and associated conditions for more than 540 disease and condition topics to help you make accurate decisions at the point of care. Organized alphabetically by diagnosis, it presents brief, bulleted points in a templated format and contains more than 100 diagnostic and therapeutic algorithms. Edited by Frank J. Domino, Robert A. Baldor, Kathleen A. Barry, Jeremy Golding, and Mark B. Stephens, this up-to-date, bestselling reference delivers maximum clinical confidence as efficiently as possible, allowing you to focus your valuable time on providing high-quality care to your patients.

Circulatory conditions are involved both in the oncologic disease itself and in its treatment, with a direct impact on therapeutic planning for patients. At the same time, it goes without saying that cancer and its treatment affect the circulatory system, be it arterial, venous or lymphatic.This book explores the interface between vascular surgery and the various clinical and surgical oncological specialties, highlighting which types of neoplasm are most common and focusing on those that more frequently cause or are influenced by vascular diseases. The diagnostic procedures for these tumors and the most suitable types of treatment are also discussed.The content is divided into three sections: I – Surgical Oncology, II – Clinical Oncology and Oncohematology, and III – Vascular and Endovascular Surgery. The first section presents the most common types of tumor in each surgical oncology specialty, and the most frequent tumors associated with vascular complications. The diagnosis, staging, prognosis and oncological treatments are discussed, while associated vascular complications, such as vascular invasion, venous thrombosis, and arterial thrombosis, are described. The second section focuses on general aspects of Clinical Oncology and Oncohematology in addition to the most frequent vascular complications related to solid and hematological cancers and its treatment (chemotherapy, radiotherapy, bone marrow transplantation). The third section includes a more detailed approach to vascular events and diseases commonly found in cancer patients, in addition to technical discussions regarding vascular reconstructions associated with tumor resection, vascular access, among other topics.At the end of each chapter, the editors comment and highlight the most important challenges for vascular surgeons who dedicate their lives to treating cancer patients.Given its scope, the book offers a valuable resource for medical specialists and professionals in training in the fields of vascular surgery and angiology, clinical oncology, oncohematology and surgical oncology.

Sex/gender - specific medicine (SGM) is defined as the practice of medicine based on the understanding that biology and social roles are important in men and women for disease prevention, screening, diagnosis, and treatment. Current research demonstrates differences in disease incidence, symptomatology, morbidity, and mortality based on sex and gender. Sex/gender-specific medicine is a fundamental aspect of tailored therapy and precision medicine. Therefore, the variables must be considered in medical education and practice as well as in research models ranging from human participants, animals and cells. Gastroenterology is very big and important division of Internal Medicine, which include esophagus, stomach, small and large intestine, pancreatobiliary tract and liver. Nowadays estrogen is known to play a key role in the prevention of colon cancer and progression of liver cirrhosis and hepatocellular carcinoma, especially in women. This book covers the sex/gender-specific medicine inthe area of gastrointestinal (GI) tract in the adults as well as in the pediatrics and in the gut microbiota.

The fully updated fifth edition of this highly successful textbook provides an integrated symptom- and issue-based approach to internal medicine with easily accessible, high-yield clinical information. For each topic, carefully organized sections on different diagnoses, investigations, and treatments are designed to facilitate patient care and examination preparation. Numerous clinical pearls and comparison tables are provided to help enhance learning, and international units (US and metric) are used to facilitate application in everyday clinical practice. In addition to the central tenets of internal medicine, the book covers many highly important, rarely discussed topics in medicine, including: palliative care, obstetrical medicine, transfusion reactions, needle stick injuries, interpretation of gram stain, depression and code status discussion. This fifth edition additionally includes new coverage of the coronavirus-19 and cancer survivorship while being fully updated throughout. Authors present this information in a streamlined fashion, preserving the book's pocket-sized, quick reference format. Approach to Internal Medicine continues to serve as an essential reference primarily for medical students, residents, and fellows -- with practicing physicians, nurses, and advanced practice providers also finding the text of value as a point of care reference.

This book provides a detailed description of laryngeal procedures performed under topical anesthesia in an office setting. The last two decades have witnessed a major evolution in laryngology practice toward office-based surgery, thus reducing the risk of general anesthesia and containing healthcare costs while also hastening recovery rates from the time of diagnosis. Beginning with a comprehensive review of the anatomy and physiology of phonation, the book then provides systematic assessment of patients with voice dysfunction secondary to structural and functional laryngeal disorders. It offers detailed instructions on patient selection, safety, tolerance, and proper administration of topical anesthesia. The book supplies detailed descriptions of the various surgical techniques commonly used in office-based laryngeal surgery using color illustrations, photographs and videos. Different surgical approaches are presented including transcervical, transnasal and per-oral techniques. Thebook also supplies a thorough review of the literature on the current status of the most commonly performed office-based laryngeal surgeries including patient care, surgical outcome, and complications. Office-Based Laryngeal Surgery will help laryngologists operating on awake patients in an office setting to be both well-equipped and well-informed.

This book comprehensively addresses female and male fertility preservation. It discusses in detail all major aspects of fertility preservation in both sexes, explains the basis of fertility preservation, and highlights the currently available techniques; further chapters are dedicated to specific diseases. The book offers an essential reference guide for all physicians, specialists or not, seeking to improve their grasp of female and male fertility preservation.

Concise, portable, and user-friendly, The Washington Manual® Cardiology Subspecialty Consult, Fourth Edition, provides essential information on inpatient and outpatient management of common diseases and disorders. Edited by Drs. Justin S. Sadhu, Mustafa Husaini, and Dominique S. Williams, this edition offers state-of-the-art content on disease pathophysiology, diagnostic tools, and management options, including new biomedical discoveries and novel therapeutics. Ideal for residents, fellows, and practicing physicians who need quick access to current scientific and clinical information in cardiology, the manual is also useful as a first-line resource for internists and other primary care providers.

Over the course of the previous seven editions, Pediatric Nephrology has become the standard reference text for students, trainees, practicing physicians (pediatricians, nephrologists, internists, and urologists), subspecialists, and allied health professionals seeking information about children's kidney diseases. It is global in perspective, reflecting the fact that the international group of editors are all acknowledged world experts. The latest edition of this text is no different, providing a comprehensive, state-of-the-art overview on pediatric nephrology. Much like the previous edition, the latest edition reviews the most critical aspects of the field. Topics covered include developmental physiology and diseases, renal physiology and diagnostic approaches, glomerular disease, kidney involvement in systemic diseases, renal tubular disorders, homeostasis, cystic kidney disease and related disorders, urinary tract disorders, hypertension, acute kidney injury, and chronic kidney failure.Unlike the previous edition, however, the chapters in this edition now combine physiology, clinical management, and pathology for ease of use. The latest edition also includes a new section on the evaluation of different disorders that can have multiple etiologies, setting the stage for the evaluation and management of specific diseases. This book serves as a superb resource and an invaluable asset for practitioners, health professionals, and trainees seeking out information about children's kidney diseases.

Pearls for Primary Care is unique, integrating pertinent basic science information with clinical medicine. The resource bridges the information gap and provides insights for providers and students. Additionally, there are succinct yet comprehensive

This comprehensive book provides detailed practical advice on the diagnosis and surgical management of congenital and acquired conditions in infants and children. Following the great success of the first edition, the new edition has been fully updated to reflect the major developments in the field of the past decade. Advances in prenatal diagnosis, imaging, anaesthesia and intensive care as well as the introduction of new surgical techniques, including minimally invasive surgery and robotic technology that have radically altered surgical conditions are now discussed in the book. In addition new chapters have been added on surgical safety in children, surgical problems of children with disabilities and surgical implications of HIV infection in children among others. This is a superbly structured and richly illustrated guide aimed at trainees, young pediatric surgeons and general surgeons with interest in pediatric surgery. The book also serves as a handy, quick andeasy reference for those making decisions in daily practice. Pediatric Surgery, Diagnosis and Management features contributions by leading experts in pediatric surgery and pediatric urology who have unique experience in their respective fields.

•A scientific treatise which covers many aspects of basic and advanced treatment modalities of infertility. •Includes step-by-step approach to fertility management from basic to advanced procedures. •The simple format makes this book an excellent choice and a ready reckoner for practicing fertility specialists of all spectrums. •30 chapters covering the introduction, important assets and investigations, anovulation, male infertility, special conditions and intrauterine insemination (IUI) and in vitro fertilization (IVF).