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The Tata Memorial Centre Textbook of Oncology is an authoritative and comprehensive book, meticulously compiled to cover contemporary issues in oncology. It features contributions from 189 authors, culminating in 76 chapters. Authored by faculty members from the renowned Tata Memorial Centre, this textbook offers a harmonious blend of detailed information and practical approaches. It serves as a comprehensive resource that contextualizes the practice of oncology in TMC and offers insights into delivering high-quality cancer care in diverse settings. It offers an authentic overview of the TMC approach to multidisciplinary cancer care. The Textbook is designed to cater to a wide array of readers – from undergraduate medical students to postgraduates specializing in general surgery, general medicine, pediatrics, gynecology, radiation oncology, and other disciplines, and practicing community oncologists. A notable feature of the Textbook is its utility in preparing students for entrance and exit examinations. This book is an essential resource for established cancer specialists, including surgeons, medical oncologists, radiation oncologists, and those in allied fields. It is also invaluable for super-specialty students and postgraduates with an interest in cancer management, offering a comprehensive guide to the dynamic field of oncology.

The book provides basic knowledge of clinical ophthalmic signs and their application in the clinical practice of medicine. It discusses several intra and extraocular signs that help the ophthalmologists to reach a diagnosis and suggest the presence or absence of an underlying severe sight-threatening or even life-threatening disease, such as diabetes, hypertension, cardiovascular disease, hematological disorders, systemic vasculitis, rheumatological disorders, brain tumors, sarcoidosis, or infectious diseases caused by M. tuberculosis, HIV or herpes viruses. The book is divided into two sections and each chapter is dedicated to one ophthalmic sign providing its pathophysiology, significance, differential diagnosis and clues to systemic disease. Each chapter is profusely illustrated with color and black and white images, and boxes with key messages on differential diagnosis and appropriate laboratory investigations. This book serves as a one-stop resource discussing the significance of individual ophthalmic signs and their context to sensitize the physicians, both the graduates and postgraduates in training, residents and fellows in ophthalmology, family medicine and internal medicine, and practicing physicians.

This book is a timely resource for all dealing with care of the elderly. It is deliberately wide in its scope and is aimed at strengthening medical students, interns, medical post-graduates, general practitioners, physicians and specialists in renal medicine, as they practice the skill, art and science of modern medicine in caring for the elderly. Despite diversity in culture, ethnicity, food habits, health care provision and socioeconomic status, there is an.

This edited volume covers all aspects of the Neglected Tropical Disease Scabies. The contributions are organised into four themed parts. The first part reviews the history of the disease and its treatment and management, part two is dedicated to parasitology and basic research on the disease causing parasite, Sarcoptes scabei. Epidemiology and disease burden including public health issues are discussed in the third part in detail. The last section of the book is covering clinical manifestation and management. This volume is the first one of its kind, providing an insight into all aspects of the skin disease which is causing considerable morbidity and mortality. Chapters are all written by dedicated experts in their respective area of interest making the publication a must have for all scientists and clinicians as well as public health specialists dedicated to Scabies research in any aspect.

The book offers a comprehensive overview of ENT diseases during pregnancy, postpartum and lactating period. It brings together the experience of authors from more than 25 countries and aims to provide a broader understanding of the diagnosis, prevention and treatment of the ENT pathologies in pregnant and lactating women. The book is organized in 7 main parts according to the ENT subspecialties, and each chapter features a reader-friendly, uniform structure. It includes developments about COVID-19 infection. ENT Diseases: Diagnosis and Treatment during Pregnancy and Lactation will appeal to a wide readership, from ENT practitioners through allergists and pulmonologists, to trainees and students in ENT, obstetrics/gynecology.​

Every surgical subspecialty has been rapidly developing with establishment of the board certification. The Division of Endocrine Surgery (DES) of the European Board of Surgery has defined the curriculum for Endocrine Surgery to include thyroid, parathyroid, adrenal and GEP-NET surgery, and handles accreditation in Endocrine Surgery. The first examinations in Endocrine Surgery in Europe have been introduced in 2003. The main goal of the exam is to maintain a uniform and high standard of endocrine surgical professionalism across the Europe.This book was completed with the expectation that it would benefit all European surgeons looking to be certified in Endocrine Surgery. Additionally, surgeons from the United States and other non-EU countries we hope will also benefit from this book. There is a need for a specialized book that reviews evidence based endocrine surgery that aligns itself with current curriculum standards in the field. The book contains knowledge that is expected to be known on the board examination of the DES. In general, chapters start with a patient's case followed by questions. The subsequent comprehensive yet concise main text provides all the information needed for a successful DES exam and cites important references. After the patient case and questions, the text goes on to define the condition, the standard of care approach to establish the diagnosis, perform diagnostic tests of choice, review evidence-based treatment options including medical therapy, preparation for surgery. The chapters conclude with follow up care and long term outcomes. The topics discussed within this book closely follow the curriculum of the European Board of Surgery Examination.Written by experts in the field, Endocrine Surgery Comprehensive Board Exam Guide is a valuable source of preparation for the Endocrine Surgery examination and brings Endocrine Surgery to a higher level of expertise byhelping to raise the standard of training for future endocrine surgeons.

Cardiovascular disease is the leading cause of morbidity and mortality in the United States and worldwide. It is well recognized that traditional risk factors for cardiovascular disease have limited predictive utility in the identification of new cardiovascular disease cases and outcomes. Thus, investigators have argued that application of a biopsychosocial research paradigm in this field may be of particular utility in understanding cardiovascular disease pathogenesis. Accordingly, a subdiscipline within the field of behavioral medicine – cardiovascular behavioral medicine – examines interrelations among biological, behavioral, psychological, social, and environmental factors in cardiovascular health and disease. In 1989, Schneiderman and colleagues published a seminal work entitled'Research Methods in Cardiovascular Behavioral Medicine.'Since that time, there has been an exponential increase in the amount and scope of work in this topic area, but no similar edited volume has been undertaken. The present handbook provides a compendium of work in the field of cardiovascular behavioral medicine, the purposes of which are to summarize research in this area, promote transdisciplinary research and clinical practice, and encourage researchers and clinicians to consider all relevant facets of the disease process in their evaluation and study of cardiovascular disease pathogenesis and outcomes. This handbook has four sections: Section I provides perspectives on the past, present, and future of cardiovascular behavioral medicine, an overview of basic cardiovascular anatomy and physiology, cardiovascular disease classification, and application of the biopsychosocial model to the study of cardiovascular disease. Section IIcovers risk factors for cardiovascular disease from a behavioral medicine perspective, including sociodemographic, behavioral, psychosocial, biomedical, psychophysiological, and environmental risk factors for cardiovascular disease.These chapters offer a discussion of construct definitions, measurement issues, and epidemiological evidence for relations to cardiovascular disease. Section III offers review of multi-level influences in specific cardiovascular disease entities, the evidence- base for relevant biopsychosocial interventions, evaluation of the impact of cardiovascular diseases on behavior, and consideration of common co-morbidities. Section IV covers select statistical and bioethical topics relevant to the field of cardiovascular behavioral medicine. This volume is unique in several respects. First, there is no similar work available in terms of the scope of topic coverage. Second, the inclusion of relevant measurement issues and construct definitions of a comprehensive set of risk factors will be of great assistance to researchers and clinicians in this area who wish to improve their assessment of these variables yet are not familiar with or trained in the various methodologies. Third, the use of multidisciplinary contributors enhances the utility of the work. Representative disciplines include psychology, psychiatry, medicine (e.g., cardiology), nursing, epidemiology, and public health. The primary audiences for this work are researchers, clinicians, and students in each of these disciplines.

This book aims to be a single point of reference for advances in the care of geriatric populations across medical and surgical specialties. The aging population is a unique demographic with its own health challenges. Geriatricians are specifically trained to address these challenges but few medical students or residents enter geriatrics, even as the demand for geriatric expertise increases. The practices of many medical and surgical specialists are dominated by older patients who may themselves see many specialists but rarely visit geriatricians. This updated edition elucidates the most common medical conditions seen in aging patients and translates approaches to those conditions for physicians across specialties. Divided into three sections that assemble crosscutting issues, medical specialties, and surgical and related specialties, this book serves as a guide for clinicians of all backgrounds who will work with older patients as the demographic ages further.This second edition of Geriatrics for Specialists expands the number of specialist chapters to reflect growth in research in aging and clinical care for older people in dermatology, plastic surgery, and behavioral neurology. All original chapters from the first edition are extensively revised and updated to reflect the rapid growth of new knowledge in the field.

This book is targeted at ensuring frontline clinical staff including seniors, trainees and specialist nurses can easily reference the optimum investigation and management of potential TB cases. This will mirror the annual London Advanced TB course which aims to equip all of the team delivering care to have a working knowledge of the entire spectrum of the real life aspects of TB management ranging from investigation of active TB to latent screening in pre biologic therapy. It includes an update of MDR TB management and also the approaches needed to ensure the entire medico-social spectrum of TB care is addressed.

Through ten outstanding editions, Werner & Ingbar's The Thyroid: A Fundamental and Clinical Text has been the go-to reference for the most comprehensive coverage of the thyroid, including anatomy, development, biochemistry, physiology, pathophysiology, and treatment of all thyroid disorders. Now in full color throughout, the 11th Edition of this award-winning text remains the clinician's preferred source of authoritative information on the thyroid—an essential resource for all endocrinologists and thyroid surgeons.

With the development of nature science and industrial technology, more and more patients are benefitting from the rapid progress in ophthalmology, as the use of new medicine and delicate surgical therapy has ensured them the chance to restore their sight. However, some problems have come up during its development, of which the most serious one is the limitation of the ophthalmology. Eyes are not isolated organs, they are connected to our body, and thus, the general status of our body will affect the eyes'function. Therefore, it is of great importance that the ophthalmologists see the big picture while dealing with the clinical problems. Based on the above observations, we put forward the concept of Integrative Ophthalmology, and describe the ophthalmology related medical situations that are prone to be neglected in clinical practice in a bid to increase the awareness of doctors from all fields that a holistic view should be adopted in clinical practice,and it is the patients that we are treating rather than the disease. There are 9 parts in the book, containing the concept of integrative ophthalmology, intraocular and intracranial pressure gradient related diseases,and the relationship between the different general status and eye disorders. We do believe that the integrative ophthalmology is the key to the development of ophthalmology and hope readers can benefit from this book.

This volume presents and analyses the ongoing arguments, controversies, challenges and debates on thyroid disease with a view to clarifying some uncertainties, and to making suggestions that will help resolve others.Issues such as thyroid disease during pregnancy, Hashimoto's disease, Hurthle cell lesions, solitary thyroid nodules, retrosternal goiter, thyroid cancer, recurrent thyroid disease, thyroidectomy techniques, post-thyroidectomy hypocalcemia, and thyroid auto-transplantation are thoroughly explored. Richly illustrated, the book offers an invaluable tool for all specialists and trainees entrusted with the care of patients suffering from thyroid disease.

This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings.More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based onboth current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.

The introduction of new imaging methods has revolutionized the management of retinal diseases. Techniques like OCT angiography and fundus autofluorescence imaging have enabled the exploration of new perspectives for understanding the progress of diseases such as age-related macular degeneration (AMD) and diabetic retinopathy. Multimodal imaging of the retina will open new avenues for an integrated diagnostic approach in the future. This publication - like all volumes of the ‘ESASO Course Series'- summarizes the essentials of the ESASO education courses. It provides an update for retina specialists and imaging technicians. Residents and trainees will also find it to be useful for learning about new imaging techniques.

This book deals with a potentially sight threatening complication - rupture of the posterior capsule – during cataract surgery. This handbook covers the management of this problem from 3 perspectives: 1.Identifying patients at higher risk and measures to manage such patients by surgical discipline 2.Intraoperative management of posterior capsular rupture (PCR) to minimize long-term complications 3.Post-operative care for a patient who has a PCR Cataract surgery is the most commonly performed surgical procedure in ophthalmology and despite tremendous technical and technological advancements, PCR still occurs. PCR occurs both in the hands of experienced senior surgeons and the neophyte surgeons, although with a higher frequency in the latter group. Additionally, certain types of cataracts are prone to this development. If managed properly in a timely manner the eventual outcome may be no different from that of an uncomplicated case. However, improper management may lead on to serious complications with a higher incidence of permanent visual disability. Written for experienced and not-so-experienced eye surgeons alike to understand and manage PCR.

The leading reference in the field of geriatric care, Brocklehurst's Textbook of Geriatric Medicine and Gerontology, 8th Edition, provides a contemporary, global perspective on topics of importance to today's gerontologists, internal medicine physicians, and family doctors. An increased focus on frailty, along with coverage of key issues in gerontology, disease-specific geriatrics, and complex syndromes specific to the elderly, makes this 8th Edition the reference you'll turn to in order to meet the unique challenges posed by this growing patient population. - Consistent discussions of clinical manifestations, diagnosis, prevention, treatment, and more make reference quick and easy. - More than 250 figures, including algorithms, photographs, and tables, complement the text and help you find what you need on a given condition. - Clinical relevance of the latest scientific findings helps you easily apply the material to everyday practice. - A new chapter on frailty, plus an emphasis on frailty throughout the book, addresses the complex medical and social issues that affect care, and the specific knowledge and skills essential for meeting your patients'complex needs. - New content brings you up to date with information on gerontechnology, emergency and pre-hospital care, HIV and aging, intensive treatment of older adults, telemedicine, the built environment, and transcultural geriatrics. - New editor Professor John Young brings a fresh perspective and unique expertise to this edition.

This newly expanded and updated fifth edition will be the largest and most comprehensive of the five editions and new topics and chapter authors have been added. The authors have created the most comprehensive and up-to-date review of the nutritional strategies available for the prevention of disease and the promotion of health through nutrition. Patients are looking for credible information from their health care providers about a whole range of subjects covered here, including ß-carotene, lycopene, antioxidants, folate, and the myriad of bioactive phytochemicals found in garlic and other foods. With sections on cardiovascular disease, diabetes, and pregnancy among many others, this volume will be of great value to practicing health professionals, including physicians, nutritionists, dentists, pharmacists, dieticians, health educators, policy makers, health economists, regulatory agencies and research investigators. An entire section covers nutrition transitions around the world including Eastern Europe, Latin America and Asia as well as goals for preventive nutrition in developing countries. Preventive Nutrition: The Comprehensive Guide for Health Professionals, 5th Ed. is an important resource for thousands of health professionals who have been utilizing the previous editions since 1997.

This textbook provides a comprehensive and state-of-the-art overview of the major issues specific to the field of pediatric gastroenterology, hepatology, and nutrition. The first part of the book, Gastroenterology and Nutrition, presents in a systematic way the overall scope of issues encountered by children (newborn to teenagers) suffering from disorders of the gastrointestinal tract, pancreas and/or presenting nutritional issues. These chapters are structured in logical sections to facilitate consultation and include major topics ranging from congenital disorders to gastrointestinal problems of the newborn, infectious diseases of the gastrointestinal tract, and approach to nutritional problems in the various pediatric ages. The second part of the book, Hepatology, is articulated in a series of chapters which present a comprehensive review of congenital and acquired disorders of the biliary tract and liver. This section also includes a critical analysis of available diagnostic andtherapeutic procedures and future perspectives.Written by experts in the field, Textbook of Pediatric Gastroenterology, Hepatology and Nutrition: A Comprehensive Guide to Practice constitutes a much needed, innovative resource combining updated, reliable and comprehensive information with agile consultation for a streamlined approach to the care of children with such disorders.

The intention of this unique title is to bridge the gap between psychiatry and neuroscience, allowing a fruitful dialogue between both sciences. Recognizing that psychiatry has received important contributions from the basic neurosciences and that the basic neurosciences have received inspiration and objectives from the open problems of psychiatry, Psychiatry and Neuroscience: Bridging the Divide is designed to identify the borders, trends and implications in both fields today. Comprehensive and developed by a renowned group of experts from both fields, the book is divided into four parts: Epistemological Considerations About the Study of Normal and Abnormal Human Behaviors; From Basic Neurosciences to Human Brain; Neurosciences, Learning, Teaching and the Role of Social Environment and Explaining Human Pathological Behaviors: From Brain Disorders to Psychopathology. A unique and invaluable addition to the literature in psychiatry and neuroscience, Psychiatry and Neuroscience: Bridging the Divide offers an important and clearer understanding of the relationship between psychiatry and neuroscience.

This compilation presents original study results on the leading edge of neuroscience research. Each article has been carefully selected in an attempt to present substantial research results across a broad spectrum. Included in this volume are the effects of b vitamins on behavior and neurochemistry; the human hippocampus; advantages and limitations of functional magnetic resonance imaging (FMRI) of the human visual brain; reaction times as a dependent variable of memory; processing speed and memory; lateral skull base; cognitive impairment in Asperger Syndrome; assessment of proprioception; processing speed and memory; and body weight changes with antiepileptic medications.

Clinicians and students at all levels and in all primary care disciplines will benefit from the clear, practical, evidence-based writing and recommendations that address the full spectrum of clinical problems encountered in the adult primary care practice. Whether it's the answer to a screening, prevention, evaluation, or management question or a comprehensive approach to a complex condition, the reader will find a review of best evidence integrated with considerations of affordability, cost-effectiveness, convenience and patient preference. Chapters present actionable, scientifically validated guidance that allows physicians to go beyond standard consensus guidelines and provide highly personalized care. Special consideration is given to team-based approaches of primary care delivery, recognizing its increasing importance to achieving high levels of practice performance. Primary Care Medicine's digital format and quarterly updates ensure current, point-of-care decision support. New, online resources include a recommended curriculum for trainees and faculty, emphasizing a core knowledge base needed for all members of the primary care team, and access to state-of-the-art, condition-specific decision grids to facilitate patient participation in shared decision-making.

Endocrinology is a complex specialty that spans a wide range of diseases, disorders, and conditions. The field is now moving toward an increasingly personalized approach to patient management, with a greater focus on mechanisms of disease and biomarkers. Written by internationally renowned specialists, the second edition of Endocrinology in Clinica

In providing care to diabetic patients, education to patient and family members is one of the most important aspects of management. The informed decisions about self-monitoring of blood glucose (SMBG), nutrition, exercise, weight control, eye and foot care, use of oral medications and insulin, prevention of micro- and macrovascular complications cannot be effectively managed without knowledge of diabetes. Also, the factors such as desire to learn, cognitive abilities, attitudes, depression, family support, barrios to care and cultural and ethnic back ground influence the learning process. Obviously, physicians and other health care professionals play a pivotal role in providing education and care to patients with this chronic devastating disease. Most of the care of diabetes and steps to prevent its complications occurs in the institutional or private clinics. There is vast amount of literature, often confusing and contradictory, is available on multitude of topics concerning diabetes and its complications. This book has made a sincere effort to provide new and futuristic information in diabetes management, which is not overwhelming. Chapters are written as easy to understand clear information and practical guidelines by expert international clinicians and scientists. Also, the chapters in this book have made an attempt to provide unbiased and evidence-based information in a comprehensive yet concise manner to be a useful guide for practicing primary care physicians, endocrinologists and other health care providers in their quest of providing excellent care to their diabetic patients. The authors have taken meticulous efforts to provide current practice recommendation. In many chapters the tables and figures stipulate clear and concise guidance which can be used as ready reference material by busy practitioners. Unique chapter on Diabetes Registry discuss and provide guidelines how diabetes registry can help institutions, private practice clinics and individual clinicians to manage the patients with this chronic disease and its complications. The chapter on epidemiology enhances the understanding of multifaceted nature of pathophysiology and risk factors of diabetes and importance of this understanding in overall management of diabetes. The chapter on self-monitoring of blood glucose (SMBG) explores controversies and provides guidance on how parsimonious and structured use of SMBG can lead to improved glycemic control and health outcomes in diabetic patients. Easy to understand and clear guidelines on the management of pregnant diabetic patient from pre-partum to post-partum and treatment of congestive cardiac failure and hypertension in diabetic patient are outlined in specific chapters. A new concept in health care delivery ‘Medical Home'for diabetes which leverages resources and improves outcomes while holding down cost is discussed in clear and concise manner in the chapter ‘management of diabetes in primary care'. The book also describes state-of-art and evidence based information for management of diabetic neuropathy, erectile dysfunction, and diabetic foot and eye disorders. Utility of food frequency questionnaire and motivational interview, the key aspects of nutritional management are discussed in specific chapters. A clear understanding of pathophysiology and treatment of type 2 diabetes in youth as well as guidelines for management of diabetic patients during religious fasting, international travelling and shift work are described in dedicated chapters.

Auf die Bedürfnisse der täglichen Praxis abgestimmtStrukturierte, klar definierte Vorgehensweisen für Diagnostik, Therapiekonzepte und personalisierte Therapieziele.Umfassende Information, inklusive- Prävention, Früherkennung- Begleiterkrankungen: Fettstoffwechselstörungen, Hypertonie...- Folgeerkrankungen: Gefäßerkrankungen, Nephropathie, Neuropathien...- Patientenschulung: Ernährung, Lebensführung...Besonderheiten bei- Kindern/Jugendlichen, Schwangeren, alten Patienten- perioperativer Betreuung, enteraler und parenteraler Ernährung- psychiatrischen Erkrankungen einschließlich Demenz- Sport, ReisenKomplexe Fragen – kompetente Antworten- Stufentherapie individuell abgestimmt auf Begleiterkrankungen, Bedürfnisse und Möglichkeiten des Patienten- Praxistipps für typische und atypische Therapieprobleme- neue und zukünftige TherapieformenNEU u.a.- Bariatrische Chirurgie- Compliance und Empowerment- Qualitätssicherung und Versorgungsforschung- DMPs, DRGsNach den Leitlinien/Richtlinien- Deutsche Diabetes Gesellschaft (DDG)- Österreichische Diabetesgesellschaft (ÖDG)- Schweizerische Gesellschaft für Endokrinologie und Diabetologie (SGED)Interdisziplinär, topaktuell. Von den führenden Experten aus Deutschland, Österreich, Schweiz.Wissen für das optimale Diabetes-Management – gerade heute besonders wichtig.

Que doit savoir l'ophtalmologiste sur le strabisme dans sa pratique quotidienne? Les réponses à cette question guident la rédaction et les choix thématiques du rapport SFO 2013. Dans un contexte d'hyper-spécialisation et d'évolution extrêmement rapide des connaissances, des pratiques et de l'organisation professionnelle le rapporteur et les co-auteurs dressent un panorama du strabisme et des pathologies associées. Le rapport aborde les symptômes du strabisme, de l'amblyopie, du nystagmus aussi bien chez le nourrisson, l'enfant et l'adulte. Les rapporteurs insistent sur l'importance de la'correction optique'pour diminuer l'incidence du strabisme, les indications et contre-indications de la rééducation, les stratégies thérapeutiques médicales ou chirurgicales. Il accorde aussi une large place aux aspects psychosociaux de cette pathologie qui reste la maladie de toute une vie.

With the changing demographic profile and an increasing number of aging population, Asia will have disproportionately large number of persons with glaucoma, mostly with angle-closure disease. Bilateral blindness is projected in 11 millions of those with glaucoma and effective opportunistic screening, early detection and appropriate treatment measures will remain the key-to-combat glaucoma blindness. In recent years, there has been virtually an explosion of knowledge with accumulation of new information on the inheritance and pathophysiology of glaucoma. The text on glaucoma has been written by practitioners of glaucoma of national and international repute and the authors have made a sincere attempt to present the most complex information available on glaucoma in a very simple and lucid style.

Leading medical authorities and clinicians comprehensively review and critically assess the newest nutritional approaches to preventing or delaying disease processes to create the single most comprehensive resource for health professionals seeking to improve individual health outcomes through nutrition. Along the way these distinguished scientists develop specific nutrient recommendations and illuminate not only the relationship between diet on the one hand and cancer, cardiovascular disease, and diabetes on the other, but also the dietary prevention of cataracts, osteoporosis, and immune dysfunction. In addition, they examine the exciting current research linking nutritional status with the prevention of birth defects, as well as with the optimization of the health and intellectual capacity of children. Their pathbreaking reviews clearly spell out the public health implications of preventive nutrition strategies for the US and Europe, as well as emerging nations and developing countries worldwide.

Handbook of Food Fortification and Health: From Concepts to Public Health Applications Volume 2 represents a multidisciplinary approach to food fortification. This book aims to disseminate important material pertaining to the fortification of foods from strategic initiatives to public health applications. Optimal nutritional intake is an essential component of health and wellbeing. Unfortunately situations arise on a local or national scale when nutrient supply or intake is deemed to be suboptimal. As a consequence, ill health occurs affecting individual organs or causing premature death. In terms of public health, malnutrition due to micronutrient deficiency can be quite profound imposing economic and social burdens on individuals and whole communities. This comprehensive text examines the broad spectrum of food fortification in all its manifestations. Coverage includes sections on definitions of fortifications, fortified foods, beverages and nutrients, fortifications with micronutrients, biofortification, impact on individuals, public health concepts and issues, and selective methods and food chemistry. Handbook of Food Fortification and Health: From Concepts to Public Health Applications Volume 2 is an indispensable text designed for nutritionists, dietitians, clinicians and health related professionals.

'Science tends to generalize, and generaliza­ tions mean simplifications.... And generaliza­ tions are also more satisfying to the mind than details. Of course, details and generalizations must be in proper balance: Generalizations can be reached only from details, while it is the generalization which gives value and interest to the detail:'... (A. Szent-Gyorgy, Science 1964) The first edition of this book, published in German as Tabak­ abhiingigkeit in 2001, was prompted by the fact that no single volume was available in Germany or elsewhere summarising the adverse repercussions of cigarette smoking on human health. As far as my own research was able to ascertain, the last comprehensive work dealing with this subject was writ­ ten in Germany by the Dresden internist, F. Lickint, whose Tabak und Organismus was published in 1939 by the Hip­ pokrates-Verlag. All subsequent monographs in this field have tended to focus on detailed aspects, and there has been no shortage of publications on subjects such as how smokers can quit smoking, healthy eating for smokers etc. Friends and colleagues abroad have urged me to prepare an English­ language version of Tabakabhiingigkeit. In gladly complying with this suggestion, I have intentionally prepared an up­ dated and slightly enlarged new edition, taking account of the rapidly proliferating literature on the subject up to the start of 2002. The harmful sequelae of smoking are played down by politicians in many industrialised countries, including Ger­ many.

From the difficult to diagnose to the difficult to treat, Manson's Tropical Diseases prepares you to effectively handle whatever your patients may have contracted. Featuring an internationally recognized editorial team, global contributors, and expert authors, this revised and updated medical reference book provides you with the latest coverage on parasitic and infectious diseases from around the world. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Incorporate the latest therapies into your practice, such as recently approved drugs and new treatment options. Find what you need easily and apply it quickly with highlighted key information, convenient boxes and tables, extensive cross-referencing, and clinical management diagrams. Make the most accurate Tropical Disease diagnoses through a completely redesigned and modernized format, which includes full-color images throughout plus a wealth of additional illustrations online at Expert Consult. Apply the latest treatment strategies for HIV/AIDS, tropical neurology, malaria, and much more. Put the latest international expertise to work for you and your patients with new chapters covering Global Health; Global Health Governance and Tropical Diseases; Non-communicable Diseases; Obesity in the Tropics; and Emergency and Intensive Care Medicine in Resource-poor Settings. See which diseases are most prevalent in specific areas of the tropics through a new index of diseases by country, as well as online-only maps that provide additional detail. Better understand the variations in treatment approaches across the globe.

The Update compiles the most recent, widespread developments of experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.

Medical Management of Glaucoma is a comprehensive review of glaucoma, current pharmacological therapies, and treatment guidelines for the disease as put forth by the American Academy of Ophthalmologists (AAO) and European Glaucoma Society (EGS). This book will review glaucoma's definition, classes, epidemiology, risk factors, pathogenesis (especially discussing intraocular pressure, aqueous humor production, and outflow), diagnosis and assessment tools, and current therapeutic options for patients. Medical Management of Glaucoma will also give ophthalmologists and related healthcare professionals insight into how the patient is affected by their disease by reviewing quality of life issues, adherence, and costs of therapy, which is particularly significant as the management of this chronic disease should be tailored for each patient.​

A state-of-the-art and concise guide to the clinical management of pediatric endocrine disorders, the second edition of the highly regarded Pediatric Endocrinology: A Practical Clinical Guide covers the most common and challenging conditions seen by practicing endocrinologists and primary care physicians, including growth, hypothalamic, pituitary, adrenal, thyroid, calcium and bone, and reproductive disorders, as well as metabolic syndromes. This expanded second edition includes new topics being seen more commonly in pediatric endocrinology practices related to obesity and type 2 diabetes mellitus and lipid disorders. Each chapter contains an introductory discussion of the problem, a review of the clinical features that characterize it, the criteria needed to establish a diagnosis, and a comprehensive therapy section delineating the risks and benefits of the best therapeutic options available. Invaluable tables summarize the critical factors in etiology, clinical presentation, diagnosis, and therapeutic dosages. Pediatric Endocrinology: A Practical Clinical Guide, Second Edition, is a comprehensive resource for all clinicians concerned with the myriad endocrinologic disorders seen in children and adolescents.

Tentative estimates suggest that one in ten patients suffers from an adverse event in hospital. In Germany, approx. 1.8 million out of approx. 18 million inpatients suffer from adverse events; 50 percent of these cases are estimated to be avoidable. In the US, nearly 100,000 people die from the consequences of mistreatment. The intensive care units record 1.7 medical errors per patient and day. The most affected disciplines are the operative disciplines, particularly general surgery. Medical errors mainly occur when the indication for surgery is being made, during surgery and post-surgery. Suspicious oncological diagnostic results and post-operative complications are also often ignored. This book deals with complications and typical medical errors in surgery. It shows solutions and ways of dealing effectively with these errors and how to establish an efficient security management system.

Iron Physiology and Pathophysiology in Humans provides health professionals in many areas of research and practice with the most up-to-date and well-referenced volume on the importance of iron as a nutrient and its role in health and disease. This important new volume is the benchmark in the complex area of interrelationships between the essentiality of iron, its functions throughout the body, including its critical role in erythropoiesis, the biochemistry and clinical relevance of iron-containing enzymes and other molecules involved in iron absorption, transport and metabolism, he importance of optimal iron status on immune function, and links between iron and the liver, heart, brain and other organs. Moreover, the interactions between genetic and environmental factors and the numerous co-morbidities seen with both iron deficiency and iron overload in at risk populations are clearly delineated so that students as well as practitioners can better understand the complexities of these interactions. Key features of the volume include an in-depth index and recommendations and practice guidelines are included in relevant chapters. The volume contains more than 100 detailed tables and informative figures and up-to-date references that provide the reader with excellent sources of information about the critical role of iron nutrition, optimal iron status and the adverse clinical consequences of altered iron homeostasis. Iron Physiology and Pathophysiology in Humans is an excellent new text as well as the most authoritative resource in the field.

The impetus for presentation of this micro-review is to re-look at the,common problem of iron deficiency anaemia with particular reference,to current concepts of its pathogenesis, historical perspective and,impact on health in human population. Hence this warrants a critical,appraisal of the subject. It is appropriate therefore to look into its,historical perspective in addition to clearly defining the concept of iron,deficiency anaemia as a significant public health problem. It calls for,an apt definition of iron deficiency anaemia as it is generally conceived,today.

The American Cancer Society recently estimated that about 45,000 new cases of thyroid cancer will be diagnosed in the United States, with three-quarters occurring in women. The overall 5-year survival rate is about 97%, making it one of the least lethal cancers. We are experiencing an epidemic of well-differentiated thyroid cancer, in part due to the widespread use of imaging modalities that detect thyroid nodules and microcarcinomas. Concurrently, there have been a number of recent advances in surgical treatment, as well as diagnostic modalities that allow us to detect small amounts of residual local and metastatic disease. Additionally, a reexamination of past treatment regimens has led to new recommendations regarding the use of radioactive iodine, and to new therapeutic options, such as targeted therapy which have supplanted the use of more toxic chemotherapy for metastatic cancer. Multiple academic organizations have developed consensus guidelines for the management of thyroid cancer, occasionally with conflicting recommendations. In Thyroid Cancer, a renowned group of authors presents a broad overview of the pathology, pathophysiology, diagnosis, and management of thyroid cancer, with an emphasis on recent evidence-based information. State-of-the-art and a significant contribution to the literature, Thyroid Cancer is an invaluable reference for endocrinologists, oncologists, nuclear medicine physicians, radiation oncologists, primary care physicians, and surgeons who deal with head and neck cancer.

A 2ª Edição desse livro foi amplamente revista e atualizada. Além de 11 novos capítulos acrescidos a essa nova edição, os anteriores foram redistribuídos em oitoseções que privilegiam amplamente os mais diversos tópicos relacionados à Hipertensão Arterial. Epidemiologia e Prevenção; Patogênese: Papel dos Principais Determinantes na Gênese e Sustentação da Hipertensão Arterial; Medida da Pressão Arterial; Classifi cação, Estratifi cação de Risco e AvaliaçãoComplementar; Tratamento Não Medicamentoso; Tratamento Medicamentoso; Hipertensão em Situações Especiais e Hipertensão Arterial Secundária são as seções que abrigam os 69 capítulos que compõem essa nova edição. Seus editores, Andréa de Araújo Brandão, Celso Amodeo e Fernando Nobre trabalharam com o auxílio de 112 especialistas da área, com conhecimento para que as informações fossem as mais amplas e atualizadas. Eles representam as principais instituições em todo o país voltadas ao estudo, pesquisa e tratamento da Hipertensão Arterial. Esse livro, obra indispensável para todos que de alguma forma militam nesse contexto, é fruto de um trabalho de quase um ano de todos os que nele se envolveram. Disso resultaram mais de 500 páginas de difusão de conhecimentos e informações relevantes. Da mesma forma que em 2006, quando de sua primeira edição, temos convicção que a 2ª. Edição deHIPERTENSÃO representa um livro realmente indispensável.

This issue of Medical Clinics of North America provides the latest essential updates on thyroid disorders and diseases. Topics covered include the following: thyroid synthesis and physiology; hyperthyroidism; hypothyroidism; thyroid nodules; goiter; differentiated thyroid cancer; subacute, silent, and postpartum thyroiditis; thyroid and pregnancy; thyroid and the elderly; medications and thyroid hormones; thyroid and the heart; thyroid and lipids; and Graves'ophthalmology.

The Indian subcontinent is a vast land mass inhabited by over one billion people. Its rich and varied history is reflected by its numerous racial and ethnic groups and its distinct religious, cultural and social characteristics. Like many developing countries in Asia, it is passing through both demographic and epidemiological transitions whereby, at least in some parts, the diseases of severe poverty are being replaced by those of Westemisation; obesity, diabetes, and heart disease, for example. Indeed, as we move into the new millennium India has become a land of opposites; on the one hand there is still extensive poverty yet, on the other hand, some of the most remarkable developments in commerce and technology in Asia are taking place, notably in the fields of information technology and biotechnology. India has always fascinated human geneticists and a considerable amount of work has been done towards tracing the origins of its different ethnic groups. In the current excitement generated by the human genome project and the molecular and genetic approach to the study of human disease, there is little doubt that this field will develop and flourish in India in the future. Although so far there are limited data about genetic diseases in India, enough is known already to suggest that this will be an extremely fruitful area of research.

This book provides up-to-date knowledge on the role of water and fat soluble vitamins in the prevention of human diseases. The vitamins are essential food constituents with magnificent biological effects therefore, linking our biology to our lifestyle and environment. One-sided nutrition, smoking, alcohol, genetic factors, and even geographical origin interfere with our dietary intake of the vitamins. Therefore, it is not wondering that insufficient vitamin intake can impact our health and contribute significantly to the development of numerous diseases. The book offers expert reviews and judgements on the role of vitamins in our health and the link between vitamins deficiency and disease conditions at different life stages. Having knowledge about the association of vitamins and disease, as well as keeping track on the patients vitamin status has become increasingly important to physicians, clinical chemists, epidemiologists, specialists in nutrition, health professionals, researchers, and students who are interested in this area. Recent development in laboratory methods has helped making many issues in this field quantitative.

This continuing series gathers and presents original research results on the leading edge of medicine and biology. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed in this compilation include the cell cycle alteration in down syndrome; TLR agonists as immune adjuvants; heart rate variability in eating disorders; current trends in glaucoma; pharmacological aspects of borates; phage display technology and the quantitative determination of oxytocin.

- La obra se presenta como un libro de texto en el que, de forma novedosa, se combinan los principios básicos de la optometría con su aplicación clínica, todo ello con el objetivo de unir ambos enfoques, presentar las técnicas actuales para su estudio, así como dar una visión clara de la aplicación de dichas técnicas en pacientes. A través de diferentes secciones, y en un único manual, se recogen distintos aspectos básicos de la Optometría, como son los exámenes preliminares y complementarios, la refracción y la evaluación de la visión binocular, así como la corrección óptica del ojo humano. - El libro se acompaña de material online, disponible en www.studentconsult.es, con el objetivo de que los alumnos puedan completar la formación en determinadas áreas, en las que se exigen más créditos y horas prácticas. En la página web podrán encontrar: - Preguntas de autoevaluación - Casos clínicos - Galería de imágenes - Una colección de vídeos cortos que recogerán las principales técnicas que han de conocer tanto alumnos como profesionales -'Optometría. Principios básicos y aplicación clínica'es una obra de texto dirigida fundamentalmente a los estudiantes de Grado de Óptica y Optometría, pero también a estudiantes de postgrado e incluso a profesionales en activo con interés en la actualización de las nuevas técnicas de Óptica y Optometría que se llevan a cabo en la práctica clínica diaria. - Libro de texto en el que se combinan los principios básicos de la optometría con su aplicación clínica, para así unir ambos enfoques, presentar las técnicas actuales para su estudio y dar una visión clara de la aplicación de dichas técnicas en pacientes. - Aborda la actualización de las nuevas técnicas de Óptica y Optometría que se llevan a cabo en la práctica clínica diaria. - Incluye el recurso online en ingles Student Consult, el cual contiene: preguntas de autoevaluación, casos clínicos, galería de imágenes y vídeos que recogen las principales técnicas.

Veja cada assunto com mais clareza com o apoio de uma abordagem visual dos problemas médicos do dia a dia!Este livro combina centenas de extraordinárias imagens de Netter com resumos concisos do pensamento médico mais atual das condições/doenças, diagnósticos, tratamentos e protocolos mais frequentes, para serem usados como guias de referência de uso fácil e rápido.• Aumente seu conhecimento em clínica médica com o auxílio das mais de 500 extraordinárias ilustrações realizadas pelo mestre ilustrador Frank H. Netter e por outros artistas que trabalham de acordo com a tradição de Netter.Esses outros profissionais criaram ilustrações exclusivas para esta edição.• Faça uma revisão da situação da clínica médica nos dias atuais - incluindo assuntos que estão se tornando mais frequentes, como a obesidade e o transtorno do estresse pós-traumático - por meio de 40 novos capítulos, da expansão de muitos capítulos e de diversas novas imagens.• Localize rapidamente a informação desejada graças aos algoritmos coloridos de forma codificada.• Consulte as recomendações de diretrizes práticas e de orientações para educação e apoio ao paciente graças às citações destacadas para fontes adicionais de consulta, incluindo web sites e outros recursos.• Faça uma revisão das evidências obtidas a partir dos estudos principais que influenciaram os padrões atuais de conduta.Contém ilustrações de Netter educativas e memoráveis, que fornecem uma compreensão visual rica de todos os conceitos. O resultado é uma excelente fonte para consulta clínica contínua, assim como para a educação do paciente e da equipe de trabalho!

This book comprehensively summarizes the adverse effects of tobacco smoking on human health. The current second edition has integrated a large set of new data that have been published in numerous scientifc studies and meta-analyses over the past few years. Unfortunately, the harmful sequelae of tobacco smoking are played down by the ind- try and politicians in many industrialized countries. However, about 800,000 people/year in the EU die from the immediate consequences of smoking. The particularly insidious feature of tobacco consumption is that smoking-attributable harmful effects on health do not generally become apparent until three or four decades after smoking initiation. Although some positive changes in the legislative handling of tobacco have appeared in the past fve years, we still need to form a pact, sealed by politicians, the medical prof- sionals, teachers and the media, to target the problem across nations. In this respect, a minority of countries, including the US and the UK, have given positive examples. There are four areas that need to be improved in future: (1) strict bans on tobacco adv- tisement on a global level, (2) better measures to protect against side-stream (passive) smoke exposure, (3) establishment of prevention programs, especially for children and (4) tre- ment of tobacco addiction.

Evidence-based nutritional interventions are now a critical component of preventive medicine, employed in a wide variety of medical scenarios. Preventive Nutrition: A Comprehensive Guide for Health Professionals, Fourth Edition gives health professionals up-to-date, comprehensive reviews that evaluate the dietary practices and interventions that have been shown to reduce disease risk and improve health outcomes. This is the flagship volume for the book series, Nutrition and Health, which has become an essential tool for health professionals. As the state of global health and nutrition have changed much since the publication of the Third Edition, this major revised and expanded Fourth Edition includes newly authored chapters and features analysis of the results of the Women's Health Initiative, the largest intervention study ever undertaken and completed in postmenopausal women. Other new material includes chapters reviewing the evidence concerning econutrition, micronutrients and major cancers, and cognitive function and other mental health areas. Also discussed are the importance of gastric acid secretions, the nutritional effects of current therapies, and the latest information on the biology of obesity and its relationship to Type 2 diabetes. One key new feature of this edition is a chapter on behavioral strategies to help assure compliance with dietary regimes, maximizing the health benefits of preventive nutrition. The authors have created the most comprehensive and up-to-date review of the nutritional strategies available for the prevention of disease and the promotion of health through nutrition. Patients are looking for credible information from their health care providers about a whole range of subjects covered here, including ß-carotene, lycopene, antioxidants, folate, and the myriad of bioactive phytochemicals found in garlic and other foods. With sections on cardiovascular disease, diabetes, and pregnancy among many others, thisvolume will be of great value to practicing health professionals, including physicians, nutritionists, dentists, pharmacists, dieticians, health educators, policy makers, health economists, regulatory agencies and research investigators. An entire section covers nutrition transitions around the world including Eastern Europe, Latin America and Asia as well as goals for preventive nutrition in developing countries.

Gain fast, easy visual access to the problems most often encountered in practice! This resource combines hundreds of exquisite Netter images – including several new paintings created especially for this book - with concise summaries of the most current medical thinking on common diseases/conditions, diagnostics, treatments, and protocols - for a single easy-to-use quick-reference guide. Instructive and memorable Netter plates provide a rich visual understanding of every concept. The result is a superb source for ongoing clinical reference as well as patient and staff education. - Offers quick access to expert medical thinking on common diseases/conditions, diagnostics, treatments, and protocols. - Presents more than 500 exquisite illustrated plates by master illustrator Frank H. Netter and other artists working in the Netter tradition to enhance your understanding of the material. - Presents nearly 40 new chapters, many expanded chapters, and several new images to reflect the state of internal medicine today—including increasingly common issues like bariatric surgery and posttraumatic stress syndrome. - Offers more tables and algorithms for enhanced'at-a-glance guidance. - Features annotated citations for additional resources, including websites and other key sources for practice guidelines and patient education and support. - Presents annotated evidence from key studies that have shaped the current standard of care.

Otolaryngologists-head and neck surgeons, plastic/reconstructive and oral/maxillofacial surgeons, radiation and medical oncologists, and other clinicians interested in caring for patients with tumors of the head and neck will find this text to be a concise resource providing critical and useful information for the systematic and efficient evaluation, diagnosis, and comprehensive treatment planning and monitoring therapy for patients with malignant head and neck tumors.

Diabetic retinopathy is the most common microvascular complication of diabetes. It remains a major cause of new-onset visual loss in the United States and other industrialized nations. In Diabetic Retinopathy, Elia Duh and a panel of internationally recognized experts comprehensively assess the current state of knowledge regarding the clinical management of DR as well as its underlying mechanisms. The authors outline the current understanding of diabetic retinopathy from the perspective of clinical practice, while reviewing the multi-factorial pathogenesis and pathophysiology of DR from the standpoint of biomedical research. Also included is a discussion of emerging concepts relating to the management and treatment of DR. Informative and highly-practical, Diabetic Retinopathy provides ophthalmologists, diabetologists, endocrinologists, and internists with a highly readable guide not only to understanding diabetic retinopathy, but also to its optimal clinical management.

Had you looked up “quality of life” (QOL) in Index Medicus premature deaths. Procedures ranging from joint replacement priorto1975,yoursearchwouldhavebeenfruitless. Although and coronary bypass surgery to treatments for arthritis and thetermwasmostlikely?rstintroducedbyKarnofskyin1949 sleep disturbances do little to increase longevity; rather, they within the realm of chemotherapy for cancer patients (1), it make it easier for the person to function in his or her daily was not used as a key word in Index Medicus for another 26 life. A cynical perspective would say that clinicians are now interested in QOL to justify their existence, as interventions years. Since that time, there has been an exponential growth in such as hip replacement cannot be rationalized on the basis the number of articles about QOL. Figure 1 shows the number of preserving lives. However, as people live longer, they do of unique articles cited each year in Medline and PsycInfo: 7 in fact become more susceptible to disorders and conditions in 1970, 331 in 1980, not quite 1800 in 1990, slightly over that interfere with activities of daily living and consequently 6000 in 2000, and nearly 11,000 in 2005. Once the domain of decrease their QOL. mainly medicine and psychology, QOL has found its way into A second factor is the realization that QOL is not syno- every aspect of health care, including physiotherapy, oc- mous with the absence of symptoms: patients with serious pational therapy, social work, nursing, and others.