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The care of retinoblastoma patients is not the result of a single clinician, but it is a consortium of multiple subspecialties including ocular oncologists, pediatric oncologists, radiation oncologists, pathologists, geneticists and scientists. In the medical literature there is a lack of a comprehensive textbook that covers all aspects of retinoblastoma management. In this textbook, experts from a wide range of subspecialties have compiled their knowledge and experience to serve as a reference guide to readers. The basic idea of this book was based on the question. This book is designed to be the most comprehensive and authoritative text in one volume, co-authored by leading physicians and scientists worldwide. Nearly 70 contributors from many countries including Italy, Turkey, France, England, Mexico, Argentina, Belgium, the Netherlands, Switzerland, India, the Philippines, Finland, and the USA. This book is divided into seven sections including epidemiology/pathogenesis, clinical features, chemotherapy, radiation therapy, advanced retinoblastoma, pathology and supportive care. In this book also emphasized the quality of life in children treated for retinoblastoma by addressing not only the diagnostics and management but also visual rehabilitation, ocular prosthesis and psychosocial aspects. The book is extremely illustrative with approximately 350 photographs and included appendices at the end for quick reference of chemotherapy regimens and genetic counselling. Medicine is an ever changing, ever growing field and included sections with newer developments and future trends. Cover extensive section on pathology of retinoblastoma with illustrative images by the pioneers of ocular pathology.