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From the latest vaccination evidence, recommendations, and protocols... to new vaccine development and the use of vaccines in reducing disease, Plotkin's Vaccines, 8th Edition, covers every aspect of vaccination. Now completely revised and updated from cover to cover, this award-winning text continues to provide reliable information from global authorities, offering a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as'an indispensable guide to the enhancement of the well-being of our world,'Plotkin's Vaccines is a must-have reference for current, authoritative information in this fast-moving field. - Contains all-new chapters on COVID-19, vaccine hesitancy, and non-specific effects of vaccines, as well as significantly revised content on new vaccine technologies such as mRNA vaccines, emerging vaccines, and technologies to improve immunization. - Presents exciting new data on evolution of adjuvants across the centuries, dengue vaccines, human papillomavirus vaccines, respiratory syncytial virus vaccines, tuberculosis vaccines, and zoster vaccines. - Provides up-to-date, authoritative information on vaccine production, available preparations, efficacy and safety, and recommendations for vaccine use, with rationales and data on the impact of vaccination programs on morbidity and mortality. - Provides complete coverage of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well as epidemiology and public health and regulatory issues. - Keeps you up to date with information on each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. - Covers vaccine-preventable diseases, vaccine science, and licensed vaccine products, as well as product technologies and global regulatory and public health issues. - Analyzes the cost-benefit and cost-effectiveness of different vaccine options. - Helps you clearly visualize concepts and objective data through an abundance of tables and figures. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

This book analyses the first two years of South Africa's response to the COVID-19 epidemic, from its emergence in early 2020.Drawing on the perspectives of a range of public health experts, economists and other social scientists, and development practitioners, this book argues that understanding this early response will be essential to moderate and improve future policy thinking around health governance and epidemic readiness. This book provides a systemic analysis of not only the epidemiological progression of COVID-19 in South Africa, but also the socio-political factors that will be key in determining the future of the country as a whole, including health system challenges, socio-economic disparities and inequalities, and variable (often contradictory and tardy) policy responses. Overall, this book exposes Manichean thinking and the spurious policy dichotomies that pitch public health against human rights, economic recovery against viral vector control, and science against ideology, with lessons not just for South Africa, but also for elsewhere on the African continent, and beyond.This book will be perfect for researchers and practitioners across Public Health, Health Policy, and Global Health, as well as those with an interest in South African politics and development more generally.The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 4.0 license.

Initialement centrée sur la prévention et le contrôle des maladies infectieuses, la surveillance épidémiologique a connu un essor considérable en France depuis une vingtaine d'années, devenant l'un des axes majeurs de l'action en santé publique. Les grandes affaires de santé publique (sang contaminé, canicule, pandémie grippale, COVID-19, …) ont d'ailleurs bien montré la nécessité de pouvoir disposer d'un système de surveillance efficace, fiable et réactif. Premier ouvrage en langue française spécifiquement consacré à ce sujet, Surveillance Épidémiologique et Veille Sanitaire a pour objectifs de faire connaître aux professionnels de santé les principes des systèmes de surveillance existants, de fournir aux épidémiologistes et chercheurs des outils méthodologiques, de permettre aux étudiants et enseignants de disposer d'un manuel complet et précis et enfin d'apporter aux décideurs en santé publique des informations de référence. L'ouvrage est organisé en quatre grandes parties, dans lesquelles sont développés : - les principes généraux et l'organisation de la surveillance épidémiologique et de la veille sanitaire ; - les méthodes et théories spécifiques à ce domaine, avec un souci constant d'accessibilité pour les non-spécialistes ; - les différents champs d'application (pathologies ou groupes de population particuliers…) ; - les relations de la surveillance épidémiologique avec les autres domaines de la santé publique (prévention, réglementation, aspects sociopolitiques…). Une attention particulière a également été portée à la surveillance en santé internationale. L'ouvrage, agrémenté de nombreux graphiques et tableaux, est complété par une série de fiches techniques expliquant et définissant les notions fondamentales de l'épidémiologie descriptive. Il intéressera tous les médecins, chercheurs, enseignants et étudiants en santé publique ainsi que tous ceux en charge de la santé publique, de la surveillance, de la veille ou de la prévention dans les agences ou organismes publics et dans les réseaux de professionnels. Cette seconde édition, traversée par la crise pandémique de la COVID-19, a vu l'ensemble de ses chapitres révisés à l'aune de la pandémie…

Vaccination programmes are of vital importance to public health and are present in virtually every country in the world. By promoting an understanding of the diverse effects of vaccination programmes, this textbook discusses how epidemiologic methods can be used to study, in real life, their impacts, benefits and risks.Written by expert practitioners in an accessible and concise style, this book is interspersed with practical examples which allow readers to acquire understanding through real-life data and problems. Part I provides an overview of basic concepts in vaccinology, immunology, vaccination programmes, infectious disease transmission dynamics, the various impacts of vaccination programmes and their societal context. Part II covers the main field tools used for the epidemiological evaluation of vaccination programmes: monitoring coverage and attitudes towards vaccination, surveillance of vaccine-preventable diseases and pathogens, seroepidemiological studies, methods to assess impact and outbreak investigation. Part III is dedicated to vaccine effectiveness and its assessment. Part IV includes an overview of the potential risks of vaccination and how to study these. Lastly, Part V deals with methods for an integrated assessment of benefits and risks of vaccination programmes. Suitable for professionals working in public health, epidemiology, biology and those working in health economics and vaccine development, Vaccination Programmes also serves as a textbook for postgraduate students in public health, epidemiology and infectious diseases.The book is aimed at all those involved in the many aspects of vaccination programmes, including public health professionals and epidemiologists. Its primary target audiences are master and doctoral students in infectious disease epidemiology and public health, post-doctoral participants of field epidemiology training programmes and public health professionals working in the post-implementation epidemiological evaluation of vaccines and vaccination programmes.The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 4.0 license

This book provides an engaging, jargon-free introduction to the threat of global pandemics, offering an overview of the many origins and triggers of pandemic events. It covers the impacts generated by novel infectious disease outbreaks across various dimensions – from social and ethical to medical and political, from media to economic and legal implications. The author discusses the preparedness strategies developed globally, the lessons learned from various outbreaks and the mitigation measures deployed — from quarantine and social distancing to data sharing and surveillance systems — including their unintended impacts. While the risk of global pandemics is certainly intensely debated by the scientific community, and increasingly by policy makers at various levels, the threat is hardly discussed in the public domain. It only permeates the media during crisis events, such as during the SARS outbreak in 2003, the West African Ebola outbreak in 2014–15, and most notably the ongoing COVID-19 global pandemic crisis. This book is thus highly timely and topical. It has a global scope, whilst at times zooming in on the implications of pandemic risk and mitigation for the Global North or the Global South. Given the interdisciplinarity of the topic, this book will be of great interest to a wider non-academic audience, as well as students from a range of subjects including politics, sociology, geography, anthropology, and international development, along with entry-level medical students keen to widen their appreciation of the social dimensions of the medical work they set out to conduct.

Highly practical yet authoritative, the new edition of Modern Infectious Disease Epidemiology has been thoroughly updated and revised in line with changing health concerns. This successful book continues to outline the tools available to the infectious disease student or clinician seeking a thorough background in the epidemiology of infectious and communicable diseases. Building on many case studies and practical scenarios included, the book then uses the tools learnt to illustrate the fundamental concepts of the study of infectious diseases, such as infection spread, surveillance and control, infectivity, incubation periods, seroepidemiology, and immunity in populations. New edition of this popular book, completely revised and updated Retains the clarity and down-to-earth approach praised in previous editions Successfully combines epidemiological theory with the principles of infectious disease treatment and control A highly experienced author brings a personal and unique approach to this important subject All students of epidemiology, infectious disease medicine and microbiology will find this text invaluable, ensuring its continued popularity.

Infectious Disease Epidemiology is a concise reference guide which provides trainees and practicing epidemiologists with the information that they need to understand the basic concepts necessary for working in this specialist area. Divided into two sections, part one comprehensively covers the basic principles and methods relevant to the study of infectious disease epidemiology. It is organised in order of increasing complexity, ranging from a general introduction to subjects such as mathematical modelling and sero-epidemiology. Part two examines key major infectious diseases that are of global significance. Grouped by their route of transmission for ease of reference, they include diseases that present a particular burden or a high potential for causing mortality. This practical guide will be essential reading for postgraduate students in infectious disease epidemiology, health protection trainees, and practicing epidemiologists.

Viral respiratory tract infections are important and common causes of morbidity and mortality worldwide. In the past two decades, several novel viral respiratory infections have emerged with epidemic potential that threaten global health security. This Monograph aims to provide an up-to-date and comprehensive overview of severe acute respiratory syndrome, Middle East respiratory syndrome and other viral respiratory infections, including seasonal influenza, avian influenza, respiratory syncytial virus and human rhinovirus, through six chapters written by authoritative experts from around the globe.

Infectious disease surveillance has evolved at an extraordinary pace during the past several decades, and continues to do so. It is increasingly used to inform public health practice in addition to its use as a tool for early detection of epidemics. It is therefore crucial that students of public health and epidemiology have a sound understanding of the concepts and principles that underpin modern surveillance of infectious disease. Written by leaders in the field, who have vast hands-on experience in conducting surveillance and teaching applied public health, Concepts and Methods in Infectious Disease Surveillance is comprised of four sections. The first section provides an overview, a description of systems used by public health jurisdictions in the United States and legal considerations for surveillance. The second section presents chapters on major program-area or disease-specific surveillance systems, including those that monitor bacterial infections, foodborne diseases, healthcare-associated infections, and HIV/AIDS. The following section is devoted to methods for conducting surveillance and also approaches for data analysis. A concluding section summarizes communication of surveillance findings, including the use of traditional and social media, in addition to showcasing lessons learned from the New York City Department of Health's experience in surveillance and epidemiology training. This comprehensive new book covers major topics at an introductory to intermediate level, and will be an excellent resource for instructors. Suitable for use in graduate level courses in public health, human and veterinary medicine, and in undergraduate programs in public-health-oriented disciplines, Concepts and Methods in Infectious Disease Surveillance is also a useful primer for frontline public health practitioners, hospital epidemiologists, infection control practitioners, laboratorians in public health settings, infectious disease researchers, and medical and public health informaticians interested in a concise overview of infectious disease surveillance.

This fully updated edition of Infectious Disease Surveillance is for frontline public health practitioners, epidemiologists, and clinical microbiologists who are engaged in communicable disease control. It is also a foundational text for trainees in public health, applied epidemiology, postgraduate medicine and nursing programs. The second edition portrays both the conceptual framework and practical aspects of infectious disease surveillance. It is a comprehensive resource designed to improve the tracking of infectious diseases and to serve as a starting point in the development of new surveillance systems. Infectious Disease Surveillance includes over 45 chapters from over 100 contributors, and topics organized into six sections based on major themes. Section One highlights the critical role surveillance plays in public health and it provides an overview of the current International Health Regulations (2005) in addition to successes and challenges in infectious disease eradication. Section Two describes surveillance systems based on logical program areas such as foodborne illnesses, vector-borne diseases, sexually transmitted diseases, viral hepatitis healthcare and transplantation associated infections. Attention is devoted to programs for monitoring unexplained deaths, agents of bioterrorism, mass gatherings, and disease associated with international travel. Sections Three and Four explore the uses of the Internet and wireless technologies to advance infectious disease surveillance in various settings with emphasis on best practices based on deployed systems. They also address molecular laboratory methods, and statistical and geospatial analysis, and evaluation of systems for early epidemic detection. Sections Five and Six discuss legal and ethical considerations, communication strategies and applied epidemiology-training programs. The rest of the chapters offer public-private partnerships, as well lessons from the 2009-2010 H1N1 influenza pandemic and future directions for infectious disease surveillance.

Sono passati sette anni dalla seconda edizione di Vaccini e vaccinazioni e in questo periodo non solo sono comparsi nuovi vaccini, ma sono state seguite, per la loro preparazione, nuove strategie basate sulla moderna capacità di riconoscere e manipolare i geni.

This unique book covers many major disease surveillance systems, drawing on the experiences of leading experts from around the world. Beginning with an overview of the newly revised International Health Regulations from the World Health Organization, the book progresses to explore surveillance systems currently in practice. Examples included are as far ranging as surveillance for antimicrobial-resistant foodborne pathogens, vaccine adverse events, influenza and HIV/AIDS, to communicable disease surveillance during complex emergencies in Iraq and Sudan. Infectious Disease Surveillance also covers the use of modern technologies to track infectious diseases, including molecular epidemiologic techniques and electronic means for data collection and distribution. Other chapters discuss evaluation of surveillance methods, ethical considerations and legal issues. The book concludes with a review of historical lessons learned from the application of surveillance in disease control—for smallpox in the 1970s and for severe acute respiratory syndrome (SARS) in 2003. A comprehensive resource to improve the tracking of infectious diseases Offers perspectives on best practices through examples of a wide variety of surveillance systems from around the globe Acts as a starting point for design of new surveillance systems Serves as an easy reference for key information Designed for frontline public health practitioners engaged in communicable disease control, epidemiologists, clinical microbiologists, and students of public health and epidemiology, this book portrays both the conceptual framework and the practical aspects of infectious disease surveillance.