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The Oxford Handbook of Paediatric Gastroenterology, Hepatology, and Nutrition has been fully updated, with new chapters on transplantation, nutritional management, and liver function and biopsy to increase the breadth and depth of coverage of this range of closely related disciplines. Written by a team of experts at the top of their field, this handbook is a practical reference manual containing information on the day-to-day management of both rare and common conditions that are encountered by those who regularly see children with gastroenterology, hepatology, and nutritional problems. Containing up-to-date information and clearly organised for ease of reference, management guidelines and references to key articles for further reading are included to make this handbook an invaluable resource for both established and trainee clinicians, as well as other members of multidisciplinary teams such as specialist nurses, dieticians, and pharmacists.

Meeting macro- and micronutrient requirements during pregnancy and early childhood is crucial for short- and long-term health and cognitive function. Meta-analyses confirm that supplementation or fortification of food with the'big four'(vitamin A, iron, zinc, and iodine) is efficacious to reduce the risk of infectious disease and improves growth and cognitive outcome. More recently, folate and vitamin B12 deficiencies during pregnancy have been shown to be associated with poor neurodevelopmental outcome and childhood obesity. The papers collected in the book at hand address the fact that maternal and fetal deficiencies can induce inadequate metabolic programming in the offspring, with increased risk for non-communicable diseases later in life. World-renowned experts in the fields of epidemiology and nutritional intervention met with those in genetics, epigenetics, and metabolic outcome to clarify the pathogenesis of micronutrient deficiencies in pregnancy and childhood, preventive methods and strategies, and opportunities for treatment.