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The role of prostaglandins in physiological events and pathological disorders related to human reproduction has been most actively investigated in the past decade. Their clinical use for fertility regulation, extensively evaluated, represents the most common clinical indication for the administration of these remarkable compounds. Thus, it is most appropriate to update the available information related to the use of prostaglandins in the regulation of human fertility to provide a background document for the benefit of clinicians and scientists. Invited experts of international reputation from various parts of the world have contributed, each in his own area of interest, to offer this book, which we hope will fill an existing gap. M. T. M. B. E. S. E. H. ix 1 Potential for prostaglandin use in controlling human reproduction K. T. KIRTON and F. A. KIMBALL BACKGROUND It was observed in 1930 that seminal plasma of a number of species contained very large amounts of substance(s) capable of altering uterine motility. These substances were subsequently demonstrated to be prostaglandins (PGs); this began the early and continued association of this group of compounds with reproduction. The activity was found to be associated with a fraction containing lipid-soluble acids, derived from prostanoic acid. Restrictions imposed by obscure sources and small amounts of material available for testing were initially impediments to their study.

Access to high quality abortion care is essential to women's health, as evidenced by the dramatic decrease in pregnancy-related morbidity and mortality since the legalization of abortion in the United States, and by high rates of maternal death and complications in those countries where abortion is still provided under unsafe conditions. The past two decades have brought important advances in abortion care as well as increasing cross-disciplinary use of abortion technologies in women's health care. Abortion is an important option for pregnant women who have serious medical conditions or fetal abnormalities, and fetal reduction techniques are now well-integrated into infertility treatment to reduce the risks of multiple pregnancies resulting from assisted reproductive technologies. Management of Unintended and Abnormal Pregnancy: Comprehensive Abortion Care is the textbook of the National Abortion Federation, and serves as the standard, evidence-based reference text in abortion care. This state-of-the-art textbook provides a comprehensive overview of the public health implications of unsafe abortion and reviews the best surgical and medical practices for pregnancy termination, as well as managing ectopic and other abnormal pregnancies. Management of Unintended and Abnormal Pregnancy: Comprehensive Abortion Care is the leading source for a comprehensive understanding of issues related to unintended and abnormal pregnancy. This textbook: is authored by internationally-known leaders in women's health care; addresses unintended pregnancy and abortion from historical, legal, public health, clinical, and quality care perspectives; includes chapters on pregnancy loss, ectopic pregnancy, gestational trophoblastic disease, and multifetal pregnancy reduction; covers treatment of pregnancies in the first and second trimester by both medical and surgical techniques; and provides resources for clinical, scientific, and social support for the abortion provider and patient.

A brave account of the social and political forces that threaten a woman's right to choose, this emotionally affecting memoir from a doctor on the front lines of the abortion debate reveals what's really at stake in the Supreme Court In America the reproductive justice debate is reaching a new pitch, with the Supreme Court weighted against women's choice and state legislatures passing bills to essentially outlaw the practice of abortion. With This Common Secret, Dr. Susan Wicklund chronicles her twenty-year career in the vanguard of the abortion war. Growing up in working-class rural Wisconsin, Susan made the painful decision to have an abortion at a young age. It was not until she became a doctor that she realized how many women shared her ordeal of an unwanted pregnancy... and how hidden this common experience remains. Now, in this raw and riveting true story, Susan and the patients she's treated share the complex, anguished, and empowering emotions that drove their own choices. Hers is a calling that means sleeping on planes and commuting between clinics in different states -- and that requires her to wear a bulletproof vest and to carry a.38 caliber revolver. This Common Secret reveals the truth about the reproductive health clinics that anti-abortion activists mischaracterize as damaging and unsafe. This intimate memoir explains how social stigma and restrictive legislation can isolate women who are facing difficult personal choices -- and how we as a nation can, and must, support them.

'Conclusions of an International Consensus Conference on Medical Abortion in Early First Trimester, Bellagio, Italy'--Cover.

In June 1999, a United Nations General Assembly Special Session reviewed and appraised progress toward implementation of the Programme of Action of the International Conference on Population and Development (ICPD) held in Cairo, 1994. At this Special Session, the Governments of the world again recognised unsafe abortion as a major public health concern, and pledged their commitment to reduce the need for abortion through expanded and improved family planning services. They also agreed that,''in circumstances where abortion is not against the law, health systems should train and equip health-s.

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.