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Das DIVI Jahrbuch präsentiert ausgewählte State of the Art-Beiträge und brandaktuelle wissenschaftliche Arbeiten aus der gesamten Intensiv- und Notfallmedizin. Neueste Ergebnisse aus der Grundlagen- und klinischen Forschung werden auf ihren Nutzen für die intensivmedizinische Praxis hin überprüft, spezielle Problemstellungen in der Klinik wie auch neue Blickwinkel auf diskutierte und etablierte Themen sorgen für eine breite, aber stets relevante Wissensvermittlung. Über die klinisch-medizinischen Fragestellungen hinaus werden auch Themenbereiche wie Organisation und Management, Qualitätssicherung oder ethische Fragen angegangen. Die Einbeziehung der aktuellen Vereinbarungen, Leitlinien oder Konsensuspapiere macht das DIVI Jahrbuch zu einer Pflichtlektüre für alle Ärzte und Pflegekräfte in den intensivmedizinischen Fachdisziplinen.

Doctoral Thesis / Dissertation from the year 2024 in the subject Medicine - General, grade: 100.00,, language: English, abstract: This research analyzed Indigenous health and lifestyle surveys and health data from the Canadian government on Indigenous people in Alberta, Canada. The information from the surveys and health data demonstrate concerns about the rising health implications and risk factors that lead to type II diabetes within Alberta's Indigenous population. This information will create a basis for developing a six-session educational protocol encompassing a detailed diabetes prevention plan that will lead to health improvement for Indigenous people with type II diabetes. The research method was a literature review design that used existing survey data. It began with a description and analysis of existing conditions, behaviors, and characteristics derived from the survey data regarding type II diabetes within the Indigenous population in Alberta, Canada. The surveys and statistics provided insight into the widespread prevalence of type II diabetes among the Indigenous population in Alberta and what to do about it. Based on Indigenous Survey Data results and data from Statistics Canada on Indigenous health status in Alberta, a six-session protocol was developed. The survey data described medical, cultural, and lifestyle care results for Indigenous people in Alberta and how the results have led to the type II diabetes numbers within the population. This study used the results of the surveys to build and formulate the six-session protocol and analyze the risk factors and high occurrence of type II diabetes among the Indigenous people in Alberta. Physicians who stated that the patients followed protocol regarding weight loss, exercised, regularly monitored blood sugar levels, and minimized risk factors showed a significant reduction in symptoms, which can lead to type II diabetes. Quality of life also improved in those who maintained a healthy lifestyle. Developing a six-session protocol with practical strategies is crucial in managing type II diabetes among the Indigenous group in Alberta. This involves implementing healthy habits and regular physical activity, promoting weight loss. In Indigenous communities in Alberta, prevention measures focus on tackling common risk factors like obesity, a sedentary lifestyle, social disparities, and an unhealthy diet. Increased health knowledge will instill prevention practices, overcome social concerns, and provide better access to lifestyle programs. This will mitigate type II diabetes within the Indigenous population in Alberta.

This book provides a thorough examination of the correlation between nutrition and stroke. It delves into the interplay between nutrition and brain functions, neurogenesis, and cognitive functions. Additionally, it investigates how various types of nutrition relate to stroke. Moreover, it discusses recent progress in recognizing the significant therapeutic role of different nutrients in addressing stroke. Finally, it offers an overview of nutrients as neuroprotective agents and outlines the fundamental principles of nutrigenomics.

Obesity is a global pandemic rising beyond the status of a lifestyle disorder, and its consequences include impaired metabolism, energy disruption, and abdominal fat deposition and storage. Body Recomposition: A Comprehensive and Metabolic Alternative to Weight Loss presents information on body recomposition, which emphasizes the approach of losing fat while gaining muscle. It contains vast research on topics including factors that influence fat accumulation, strategies for weight management, healthy diet and eating patterns, physical exercise, and lifestyle strategies in healthy weight management.Features: Influence of non-alcoholic fatty liver disease (NAFLD) on stored fat accumulation and its treatment Harnessing the gut microbial arm in combating obesity Roles of leptin, ghrelin, NPY, cortisol, and diverse neurotransmitters in appetite suppression and regulation Genetic predisposition and genetic addiction obesity risk assessment and therapies Gut–brain axis role in metabolism and body recomposition Efficacy of phytochemicals in weight management and roles of drugs and natural supplements in weight management Importance of physical exercise and manageable lifestyle factors Existing commercial weight loss strategies can fail to achieve and maintain sustainable weight loss or enhance greater healthy fat loss. This book provides an improved alternative for dietitians/nutritionists, health practitioners, and clinicians, as well as food and nutrition scientists.

The fourth edition of Dr. James Rippe's classic Lifestyle Medicine textbook continues to lead and inform the rapidly growing field of lifestyle medicine. This is the discipline that focuses on the impact of daily habits and actions on both short- and long-term health and quality of life.The first edition of this comprehensive work named the field of lifestyle medicine in the academic medical literature. The fourth edition continues to span and expand the field and offers extensive evidence-based literature in virtually every aspect of lifestyle medicine. This Textbook, edited by cardiologist Dr. James Rippe, who is a leading lifestyle medicine researcher, represents the combined wisdom and recommendations of over 325 experts in virtually every aspect of lifestyle medicine. Chapter authors have been chosen because of their background as leaders in various aspects of lifestyle medicine.Lifestyle Medicine, Fourth Edition contains extensive sections on the treatment and prevention of coronary heart disease,stroke, cancer, diabetes, obesity, substance abuse, dementia, and many other clinical conditions. Key lifestyle modalities such as physical activity, nutrition, weight management, sleep, stress reduction, and positive connections with other humans are supported by detailed discussion and state-of-the-art evidence. The expanded section on behavioral medicine provides an important framework for these discussions. Every chapter has been completely revised and many new topics added, such as lifestyle medicine for nursing, psychiatry, and preventive neurology.The fourth edition of this classic text continues to serve as the leading, comprehensive textbook in lifestyle medicine. The original has been called the “indispensable bible” of lifestyle medicine, and the fourth edition of this work continues to justify this designation.There is no longer any serious doubt that daily habits and actions have a significant impact on multiple aspects of health. The fourth edition of Lifestyle Medicine provides the scientific evidence to support this assertion and will serve as an invaluable reference and guide, not only to lifestyle medicine practitioners but to all primary care physicians, subspecialty physicians, nurses, and other healthcare practitioners.

Written by a cadre of experts, this new edition provides a comprehensive, authoritative, and international view of gestational diabetes mellitus and will be invaluable to maternal-fetal medicine specialists, diabetologists, neonatologists, and a growing number of gynecologists and general physicians concerned with the management of noncommunicable diseases in pregnancy. Offers a comprehensive and authoritative guide to all aspects of the subject internationally Presents an invaluable resource for all working in diabetes, maternal-fetal medicine, and obstetrics Shows the latest developments in research in genomics and in practice with the digital clinic

The book delves into the development and therapeutic potential of Sodium-glucose Cotransporter-2 (SGLT2) inhibitors for the treatment of diabetes and cardiovascular diseases. It explores their mechanism of action, cardiovascular benefits, and role in primary and secondary protection from renal and cardiovascular diseases. The book also highlights their emerging opportunities in the management of myocardial infarction, diabetic cardiomyopathy, and congestive heart failure. It provides a comprehensive review of preclinical and clinical information on the cardiovascular advantages of SGLT2 inhibitors. Additionally, the book explores selective drugs and their effects on cardiovascular events, mortality, and safety outcomes in individuals with type 2 diabetes. The book is a valuable resource for researchers, healthcare professionals, and individuals interested in the field of SGLT2 inhibitors and their impact on diabetes and cardiovascular health.

This 2 volume set comprises of the 4th edition of Volume 1 and the 5th edition of Volume 2.The fifth edition of Volume 1 of Handbook of Obesity written by global experts covers the basic science aspects under the broad topic areas of epidemiology, etiology, and pathophysiology of obesity. Divided into 5 sections and detailed in 66 chapters, this edition covers the important advances occurring over the past decades. With a focus on science of obesity and factors participating in the etiology of obesity, this topic is studied from biological, behavioural and environmental perspectives.Volume 1 is structured into 5 parts: Part 1 focuses on the history, definitions, and prevalence of the obesity. It identifies the historical references to excess weight, obesity in art and literature, direct and surrogate measurements of adiposity and obesity related traits, epidemiology of obesity around the globe, and age, sex and ethnic variation completes this part of the volume.Part 2 explains the biological determinants of obesity. It explains the bioenergetics, energy dissipation mechanisms and exposure to experimental overfeeding, genetic and epigenetic evidence, metabolic rates, energy expenditure and energy partitioning, and the evidence on infections and adiposity.Part 3 describes the behavioral determinants of obesity. It deals with chapters related to food, beverages, and ingestive behavior, dealing with smoking, breast-feeding, and sleep duration and pattern, and sedentary behavior, occupational work, and leisure-time physical activity and obesity.Part 4 comprises of chapters explaining the environmental, social, and cultural determinants of obesity. The chapters in this section focus on the role of agriculture and the food industry in the current obesity epidemic, social and economic aspects of obesity, and ethnic and cultural differences and environmental pollutants.Part 5 of this volume discusses the health consequences of obesity. The chapters address important topics such obesity and heart disease, lipoprotein metabolism, insulin resistance and diabetes, metabolic syndrome, cancer, hepatic biology, pulmonary functions, and arthritis and gout, mental health and quality of life, growth and health disorders in pediatric populations, and on bias and discrimination affecting the obese persons.Volume 2 of the 5th Edition of the Handbook of Obesity spotlights on clinical applications for evaluation, diagnosis, prevention, and treatment of obesity. It covers on the several major developments occurred between the previous and the new edition, including the effect of SARS-CoV-2 on people with obesity, the concept of'Precision Medicine', and new medications approved by USFDA aiding patients with obesity weight loss of 15 to 20%.This volume is structured into 5 parts:Part 1 provides insights from evolution on changes in diet and physical activity, and the implications and results for preventing obesity, health care costs associated with obesity and the cost-effectiveness of obesity prevention and treatment.Part 2 deals with evaluation of overweight patients, approaches for classifying obesity and using this knowledge to evaluate patients, and addressing ethnic and racial considerations in evaluating patients with obesity.Part 3 explains the impact of lifestyle in managing obesity, which include behavioural management, diet, dietary composition, and meal timing, and the effects of physical activity and exercise in weight loss and weight loss maintenance.Part 4 is focused on medications in the management of obesity. This includes drug selection, various classes of drugs, combination of drugs affecting weight loss, effect of herbal agents on weight loss and treatment of obesity in pediatric populations, genetic diseases causing obesity and the role of drugs in treating the dyslipidemias.Part 5 discusses bariatric surgery, its history, procedure

Das DIVI Jahrbuch präsentiert ausgewählte State of the Art-Beiträge und brandaktuelle wissenschaftliche Arbeiten aus der gesamten Intensiv- und Notfallmedizin. Neueste Ergebnisse aus der Grundlagen- und klinischen Forschung werden auf ihren Nutzen für die intensivmedizinische Praxis hin überprüft, spezielle Problemstellungen in der Klinik wie auch neue Blickwinkel auf diskutierte und etablierte Themen sorgen für eine breite, aber stets relevante Wissensvermittlung. Über die klinisch-medizinischen Fragestellungen hinaus werden auch Themenbereiche wie Organisation und Management, Qualitätssicherung oder ethische Fragen angegangen. Die Einbeziehung der aktuellen Vereinbarungen, Leitlinien oder Konsensuspapiere macht das DIVI Jahrbuch zu einer Pflichtlektüre für alle Ärzte und Pflegekräfte in den intensivmedizinischen Fachdisziplinen.

This completely revised and updated Fourth Edition of the Atlas of Diabetes Mellitus provides a broad coverage of all aspects of diabetes mellitus and an extensive collection of common and rare clinical images. It aims to provide an invaluable resource for anyone interested in the management of this ubiquitous clinical condition including primary care/ family physicians, endocrinologists, physicians in training, diabetic specialist nurses and other key professionals who are likely to be involved in the care of patients with diabetes mellitus.

Volume 2 of the 5th Edition of the Handbook of Obesity spotlights on clinical applications for evaluation, diagnosis, prevention, and treatment of obesity. It covers on the several major developments occurred between the previous and the new edition, including the effect of SARS-CoV-2 on people with obesity, the concept of “Precision Medicine”, and new medications approved by USFDA aiding patients with obesity weight loss of 15 to 20%. This volume is structured into 5 parts: Part 1 provides insights from evolution on changes in diet and physical activity, and the implications and results for preventing obesity, health care costs associated with obesity and the cost-effectiveness of obesity prevention and treatment Part 2 deals with evaluation of overweight patients, approaches for classifying obesity and using this knowledge to evaluate patients, and addressing ethnic and racial considerations in evaluating patients with obesity Part 3 explains the impact of lifestyle in managing obesity, which include behavioural management, diet, dietary composition, and meal timing, and the effects of physical activity and exercise in weight loss and weight loss maintenance Part 4 is focused on medications in the management of obesity. This includes drug selection, various classes of drugs, combination of drugs affecting weight loss, effect of herbal agents on weight loss and treatment of obesity in pediatric populations, genetic diseases causing obesity and the role of drugs in treating the dyslipidemias Part 5 discusses bariatric surgery, its history, procedure and effects in details, and other surgical techniques including electric stimulation of the vagus nerve, gastric balloons, intestinal liners, and liposuction

More than 85% of people with diabetes receive their diabetes care in the primary care setting. With the busy primary care practitioner in mind, Everyday Diabetes in Primary Care: A Case-Based Approach offers dozens of diabetes cases in an easy-to-digest format—each representing a common clinical question that clinicians face in this common and complex area. For every case, fellowship-trained diabetologist Dr. Jay Shubrook shares his considerable expertise, providing authoritative, real-world guidance for your day-to-day management of patients with diabetes.

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in women and men worldwide and represents a major financial burden to world health care systems. Importantly, CVD has eclipsed cancer as the leading cause of death for women globally. Through advancements in research and clinical testing, the symptoms and risk factors for CVD have been well established for men, but not for women. Consequently, there is an immediate need for new innovative research that will bridge this gap and allow for improved early diagnosis and treatment of CVD in women. This book will serve as a guide for health care providers to better understand the physiological, biochemical, and genetic differences in heart disease in women with the goal of providing improved education, awareness and treatment of cardiovascular disease in women. The book will cover topics such as: sex dependent clinical outcomes of cardiovascular disease, cardiac protection by estrogen, cardiac health during menopause, cardiac rehabilitation programs, fitness and exercise, cardio-oncology, shift work and the CVD risk, and pregnancy related CVD.

The 4th edition of the Oxford Textbook of Children's Sport and Exercise Medicine is the definitive single-volume reference in the field presented in four sections Exercise Science; Exercise Medicine; Sport Science; and Sport Medicine.

Figlia di un riduzionismo esasperato, la medicina contemporanea ha prodotto un sistema che cura i sintomi ignorando le cause. I processi fisici, chimici, biologici, mentali e sociali che caratterizzano l'essere umano non possono non essere percepiti che nelle loro molteplici interrelazioni. Questo libro è un ausilio per quei medici e cardiologi che si interrogano costantemente sul mistero della guarigione, che recepiscono i contenuti euristici dalle proprie esperienze professionali e che sono interessati a possedere il maggior numero di strumenti per guarire quello specifico paziente che incontrano nelle difficoltà della quotidianità; allo stesso tempo può anche aiutare il paziente cardiologico a intraprendere un cammino tra le diverse terapie disponibili, meno praticate o conosciute, potendone così valutare scientificità e affidabilità.

This handbook volume is part of the Reference Series: Micro/Nano Technologies. This individual volume provides a comprehensive, self-contained, and authoritative knowledge in nanomedicine. It covers the theoretical and practical aspects of functionalizations of nanoparticles as nanomedicine, including surface activation, characterization, and microemulsion systems. As a Springer Major Reference Work it is continuously updated online, allowing newcomers and other readers to keep in touch with the most up-to-date information.The book is particularly recommended to undergraduates, postgraduates, researchers, scientists, and field experts. It will inspire innovations in the highly interdisciplinary field of nanomedicine.

Diabetes is one of the chronic diseases of metabolism, which procure around 2.8% of the world's demographics. It is up surging across every continent in the world. Treatment to prevent this disease is an important challenge for researchers. Conventional drugs for the treatment of this disease improve insulin sensitivity. Increased production of insulin results in a decreased blood glucose level. However, they have additional side effects and do not always provide satisfactory results. The WHO estimates that approximately 80% of the world's population rely on traditional medicine for their primary health care and many plants have ethnomedical claims of usefulness in the treatment of diabetes and other chronic diseases globally and have been employed empirically in antidiabetic, antihyperlipidemic, antihypertensive, anti-inflammatory and antiparasitic remedies. Plants are paramount for potential lead candidates'discovery, which can play an important role in drug discovery and development projects. Plants are an alternative source to overcome this problem as they contain various phytocompounds which show protective effects against diabetes.

Cardiovascular Diseases (CVDs) are the number one cause of death and disability globally, being the most important public health problem that needs to be tackled as more people die annually from CVDs than from any other cause. Over three-quarters of CVD deaths take place in low- and middle-income countries. This book on cardiovascular diseases provides an overview of the global and regional challenges associated with CVDs. Coupled with case studies and theoretical concepts, it helps the reader to contextualize CVDs in the broader public health system and the administrative aspects of practicing CVD control approaches for improved population health in their local setting. Key Features:1. Covers existing and emerging issues in cardiovascular disease epidemiology and prevention.2. Has a multidisciplinary approach in content and audience.3. Connects with health systems and relevant sustainable development goals.4. Provides case studies for enabling readers to understand and apply evidence-based solutions to key public health issues.5. Has inputs from globally renowned public health experts.

This book contains seven selected chapters covering advances in health and disease. Chapter One reviews the properties of plasmids and their role in human diseases. Chapter Two examines chronic kidney disease and its disturbances on the gastrointestinal system. Chapter Three reviews ginsenosides and their health benefits as well as their role in disease prevention. Chapter Four discusses how first-generation somatostatin analogues changes the outcome of acromegaly. Chapter Five is an overview of the pathophysiology of diabetes mellitus and its impact on the gastrointestinal system. Chapter Six is a narrative review of superior mesenteric venous thrombosis. Chapter Seven is an overview of hub genes and their role in myocardial ischemia, additionally it is discussed how exercise can modulate, improve, and reverse these pathways.

This book examines new technologies (device and pharmacologic) that have evolved over the past few years in treating peripheral arterial disease. Chapters offer optimal strategies to treat PAD, supported by peer-reviewed data. The pillars of this strategy will focus on (a) changing vessel compliance to allow better lumen expansion, (b) less recoil and dissections, and (c) less bailout stenting. Chapters also review embolic protection devices and apply the adjunctive use of anti-proliferative therapy to maintain good long term outcomes. In addition, the book reviews drug coated balloons and drug eluting stent technologies and other means of drug delivery into the vessel wall. The goal of this book is to discuss all these emerging technologies under the strategy of treating patients with the focus on both acute and long term outcomes. Featuring world renown experts, this book offers a critical and comprehensive overview of the current data and future directions that would pave the wayfor optimal PAD management.Peripheral Arterial Interventions is an essential resource for physicians, residents, fellows, and medical students in cardiology, radiology, vascular surgery, primary care, and health promotion and disease prevention as well as internal and vascular medicine specialists.

The book is an evidence-based source of information on women's health issues for health professionals already practicing lifestyle medicine, as well as an entry level textbook for those new to the field of lifestyle medicine. The collective expertise of each of the editors along with content provided by leaders within the American College of Lifestyle Medicine fills a much-needed void within the specialty of Lifestyle Medicine and is for providers of women's health globally.

This'patient-oriented'book was written as a meeting ground for practicing clinicians, allied health professionals, and clinical researchers to provide a practical guide for the contemporary assessment and management of patients with heart failure and cardiomyopathy. It revolves around broad patient scenarios to elegantly (or expertly) guide diagnostic and management strategies. Combining the talents of over one-hundred experts in the field, the book also endeavors to challenge the reader with areas of current controversies and opportunities for clinical investigation with the goals of both orienting clinicians and stimulating their research passions. Key Features Provides practical guidance based on real-life heart failure scenarios Discusses both acute and chronic care patient-oriented scenarios Covers up-to-date and novel concepts in heart failure Features the perspectives of current debates and controversies in heart failure Highlights the opportunities for research in this field

This volume focuses on the potential use of probiotics in treating metabolic disorders such as diabetes mellitus, metabolic acidosis, and gut dysbiosis. Chapters draw an association between gut microbiota and its diversity with metabolic diseases like diabetes, obesity, related liver and gut disorders; gut-brain axis; increased inflammation, and a compromised immune system resulting from these manifestations and scope of intervention with probiotics. Special attention is laid on describing the mechanisms of action of such beneficial effects of probiotic administration. The ability of probiotics to decrease metabolic endotoxemia by restoring the disrupted intestinal mucosal barrier is also included.The volume is a comprehensive compilation describing the scope and application of probiotic and prebiotic therapy in treating metabolic disorders. Readers will discover how probiotics are not just confined to the microbiology industry but are showing promising results in the medical and pharmaceutical sectors.

For over sixty years, McDonald's Blood Flow in Arteries has remained the definitive reference work in the field of arterial hemodynamics, including arterial structure and function with special emphasis on pulsatile flow and pressure. Prestigious, authoritative and comprehensive, this seventh edition has been totally updated and revised with many new chapters. This edition continues to provide the theoretical basis required for a thorough understanding of arterial blood flow in both normal and pathological conditions, while keeping clinical considerations and readability paramount throughout.Key Features The definitive reference work on arterial hemodynamics Fully updated and revised to cover all recent advancements in the field

Since its first edition, Men's Health has established itself as the essential reference for practitioners across the spectrum of medicine - including those working in urology, andrology, cardiology, endocrinology, family practice and mental health. For this fully updated fourth edition the editors have again assembled an international team of expert authors to write on an encyclopedic range of topics, making this an invaluable resource for any health professional interested in maintaining and improving the health of their male patients. Comprehensive coverage of every aspect of men's health and the gender gap. Includes the latest research on cardiovascular risks. Assesses the specific issues concerning men and cancer. Examines the often overlooked aspects of mental health as it affects men. Incorporates new developments in metabolic medicine and men.

O livro Fisioterapia Vascular Periférica é um marco na fisioterapia vascular brasileira, pois reúne, pela primeira vez, na língua portuguesa, uma coletânea de capítulos focados na angiologia e fisioterapia vascular, diferenciando-se de outros livros da área cardiovascular que possuem foco em cardiologia e informações esparsas sobre essa área em evolução dentro da intervenção fisioterapêutica.

This book reviews the application of artificial intelligence and machine learning in healthcare. It discusses integrating the principles of computer science, life science, and statistics incorporated into statistical models using existing data, discovering patterns in data to extract the information, and predicting the changes and diseases based on this data and models. The initial chapters of the book cover the practical applications of artificial intelligence for disease prognosis & management. Further, the role of artificial intelligence and machine learning is discussed with reference to specific diseases like diabetes mellitus, cancer, mycobacterium tuberculosis, and Covid-19. The chapters provide working examples on how different types of healthcare data can be used to develop models and predict diseases using machine learning and artificial intelligence. The book also touches upon precision medicine, personalized medicine, and transfer learning, with the real examples. Further, it also discusses the use of machine learning and artificial intelligence for visualization, prediction, detection, and diagnosis of Covid -19. This book is a valuable source of information for programmers, healthcare professionals, and researchers interested in understanding the applications of artificial intelligence and machine learning in healthcare.

This new edition of an acclaimed text reviews the evidence for best practice in Maternal-Fetal Medicine, to present the reader with the right information, with appropriate use of proven interventions and avoidance of ineffectual or harmful ones. The information is presented in the right format by summarizing evidence succinctly and clearly in tables and algorithms. The aim is to inform the clinician, to reduce errors and'to make it easy to do it right.'The volume can be purchased separately or together with the companion volume on Obstetric Evidence Based Guidelines (set ISBN 9780367567033).The Series in Maternal-Fetal Medicine is published in conjunction with the Journal of Maternal-Fetal and Neonatal Medicine.From reviews of previous editions:'An excellent resource with quick and easy protocols… this book has a permanent spot on my shelf.'— Doody's Review Service

This volume presents eight chapters, each focused on a particular topic in health and disease. Chapter One reviews the mechanism of action and clinical evidence available on the effect of sodium-glucose co-transporter 2 inhibitors (SGLT2i) on glycemic control, weight, blood pressure, and cardiovascular and renal outcomes in patients with type 2 diabetes. Chapter Two explains the diagnosis and management of bruxism, a disorder defined by the repetitive involuntary activity of muscles of mastication characterized by teeth clenching or grinding. Chapter Three details the diagnosis and treatment options for acute appendicitis. Chapter Four focuses on the evolution of pharmacological management of gastroesophageal reflux disease (GERD) with a focus on the current updates in terms of the safety and efficacy of acid suppressive therapy (AST). Chapter Five explores the profile of pediatric patients with bruxism following a therapeutic care program in a health center specialized in bruxism during childhood. Chapter Six discusses the role of anti-reflux surgery in GERD, which is used in cases where AST fails to treat the disease. Chapter Seven provides another perspective on the diagnosis and management of acute appendicitis. Finally, Chapter Eight focuses on the diagnosis of GERD, as well as its medical, endoscopic and surgical management.

This book helps to recognize the rights of refugees and provides a framework to identify and approach health needs, from basic elements like service mapping and initial interventions to more complex elements of ongoing healthcare and support and broader topics such as migration public health, migration policy and health systems. Beyond biomedical frameworks, it draws on socio-ecological models to inform assessments and integrated models of care to improve health and health equity. Set out in three comprehensive sections: public health theory (Part 1), applied public health (Part 2), and clinical approaches (Part 3), this book draws on multiple disciplines and insights from humanitarians, academics, policy experts, and clinicians from diverse contexts, with expertise in forced migration, to create an accessible reference tool to inform healthcare professionals'interactions with forcibly displaced individuals and populations in all contexts for both high and low resource countries. Apart from providing information across the spectrum of health issues, clinical specialties and global contexts, it discusses associated areas, including human rights and law, public health, medical anthropology and cultural awareness.Key Features: Bridges the gap between existing academic literature on refugee health and guidelines for health management in humanitarian emergencies Helps to develop an integrated approach to healthcare provision, allowing healthcare professionals and humanitarians to adapt their specialist knowledge for use in forced migration contexts and with refugees. Recognizes the complex and interconnected needs in displacement scenarios and identifies holistic and systems-based approaches. Covers public health theory, applied public health and clinical aspects of forced migration.

Con el objetivo de aportar a la educación médica continuada de la región, la Universidad Pontificia Bolivariana y la Clínica Cardio VID han decidido publicar el primer libro sobre cardiología y enfermedades cardiovasculares para abordar problemas de actualidad con la más alta calidad científica, en el que además se pueda compartir la experiencia de uno de los centros de atención cardiovascular y de los posgrados en esta área más tradicionales de la región y Colombia. Este libro es una obra escrita por médidcos cardiólogos clínicos y subespecialistas, cirujanos cardiovasculares, residentes de cardiología clínica, cardiología pediátrica, ecocardiografía, anestesiología cardiovascular, cirugía cardiovascular y medicina interna, que aborda problemas clínicos cotidianos de patologías cardiovasculares que permitirá que los lectores profundicen en ellos.

Der Arzneiverordnungs-Report ist seit 1985 eine gemeinsame Publikation von Autoren aus Pharmakologie, Klinik, Praxis, Gesundheitsökonomie und Krankenversicherung. Basis sind die Verordnungsdaten von Arzneimitteln für ambulante Patienten der gesetzlichen Krankenversicherung (GKV). Datenbasis des Jahres 2019 sind 820 Millionen Verordnungen von 179.805 Vertragsärzten und 63.360 Vertragszahnärzten für 73,195 Mio. GKV-Versicherte.Die allgemeine Verordnungs- und Marktentwicklung wird in 5 Kapiteln dargestellt, in denen zusätzlich 31 neue Arzneimittel des Jahres 2019, Biologika und Biosimilars, 10 Jahre AMNOG und europäische Arzneimittelpreise für Biosimilars thematisiert werden. Die speziellen Verordnungsdaten der 3000 meistverordneten Arzneimittel werden in 39 Kapiteln für die führenden Indikationsgruppen evidenzbasiert analysiert.

Published in 1981: The main topic of the book is the growth of white adipose tissue as a whole as well as the level of the local fat depots.

With an exponential growth in the number of older adults, understanding the common disorders of the elderly patient requiring cardiac care is becoming increasingly important. Incorporating recent advances in the field, Tresch and Aronow's Cardiovascular Disease in the Elderly 6th Edition has been completely revised and updated to provide cardiologists, primary care physicians, geriatricians and other clinicians caring for the elderly a comprehensive and accessible overview of the epidemiology, pathophysiology and treatment of cardiovascular disorders in older patients.

Advancements in data science have created opportunities to sort, manage, and analyze large amounts of data more effectively and efficiently. Applying these new technologies to the healthcare industry, which has vast quantities of patient and medical data and is increasingly becoming more data-reliant, is crucial for refining medical practices and patient care. Data Analytics in Medicine: Concepts, Methodologies, Tools, and Applications is a vital reference source that examines practical applications of healthcare analytics for improved patient care, resource allocation, and medical performance, as well as for diagnosing, predicting, and identifying at-risk populations. Highlighting a range of topics such as data security and privacy, health informatics, and predictive analytics, this multi-volume book is ideally designed for doctors, hospital administrators, nurses, medical professionals, IT specialists, computer engineers, information technologists, biomedical engineers, data-processing specialists, healthcare practitioners, academicians, and researchers interested in current research on the connections between data analytics in the field of medicine.

The field of lifestyle medicine, which is the study of how daily habits and actions impact on both short- and long-term health and quality of life, continues to expand globally. The scientific and medical literature that supports the success of these lifestyle habits and actions is now overwhelming. Thousands of studies provide evidence that regular physical activity, maintenance of a health body weight, following sound nutritional practices, stress reduction, and other good practices all profoundly impact both health and quality of life. Following its predecessors, Lifestyle Medicine, Third Edition, is edited by lifestyle medicine pioneer, cardiologist Dr. James Rippe. This edition has been thoroughly updated and represents the expert opinions of 20 section editors as well as more than 150 expert chapter authors whose knowledge span all aspects of this emerging discipline. Topics cover lifestyle medicine practices including regular physical activity, proper nutrition, and weight management. These principles are applied to the prevention and or treatment of a wide variety of chronic conditions ranging from heart disease and diabetes to cancer, mental health, addiction, and injury prevention. This book serves as evidence base for individuals who wish to practice lifestyle medicine or incorporate some of its principles into either general medicine or subspecialty practice. It provides valuable information to healthcare workers in the fields of nutrition, exercise physiology, psychology, behavioral medicine, health promotion, and public policy where lifestyle medicine principles play an ever-increasing role.

Diabetes mellitus ist die chronische Erkrankung mit der höchsten Inzidenzrate weltweit. Neben Risikiofaktoren wie Bewegungsmangel und Übergewicht spielen vor allem die deutlich gestiegene Lebenserwartung und damit auch das parallel steigende Diabetesrisiko die Hauptrolle. Der multimorbide und gehandicapte Mensch, d. h. der geriatrische Mensch mit Diabetes, zeigt im Gegensatz zum jungen, nicht-geriatrischen Menschen mit Diabetes deutlich andere körperliche, seelische und kognitive Voraussetzungen. Die sich daraus ableitenden Einschränkungen im Alter erfordern ein im Gegensatz zur herkömmlichen Therapie teilweise konträres Handlungskonzept in Bezug auf Diagnostik und Therapie. Beispiel: Ernährung: Adipositas verhindern beim jungen Diabetiker vs. Mangelernährung verhindern beim geriatrischen Menschen mit Diabetes. Die sonst wichtigste Säule in der Diabetestherapie, die Selbsttherapie des Patienten, ist mit den herkömmlichen Methoden nicht mehr erfolgreich umsetzbar. Oft muß die Umgebung, in Form von Angehörigen oder Helfern, diese Therapieaufgabe unter ganz anderen Prämissen, als dies im ärztlichen und pflegerischen Kontext möglich ist, übernehmen. In diesem Buch vermitteln anerkannte Experten aus der klinischen Praxis, basierend auf Fallbeispielen, einen sehr differenzierten, interaktiven Einblick in die Welt des älteren Menschen mit Diabetes mellitus.

The Manual of Hypertension of the European Society of Hypertension reflects emerging concepts that have the potential to impact diagnostic and therapeutic approaches to hypertension. Updating all material, this new edition also delves into a number of areas that have received heightened interest in recent years or have become a matter of debate due to the controversial interpretation of the available data.FEATURES Reflects emerging concepts impacting diagnostic and therapeutic approaches Explores background, history, epidemiology, and risk factors Describes pharmacological, nonpharmacological, and medical treatments Examines hypertension in special populations and treatment

Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes provides an in-depth examination of the role of endothelium and endothelial dysfunction in normal vascular function, and in a broad spectrum of clinical syndromes, from atherosclerosis, to cognitive disturbances and eclampsia. The endothelium is a major participant in the pathophysiology of diseases, such as atherosclerosis, diabetes and hypertension, and these entities are responsible for the largest part of cardiovascular mortality and morbidly. Over the last decade major new discoveries and concepts involving the endothelium have come to light. This important reference collects this data in an easy to reference resource. Written by known experts, and covering all aspects of endothelial function in health and disease, this reference represents an assembly of recent knowledge that is essential to both basic investigators and clinicians. - Provides a complete overview of endothelial function in health and diseases, along with an assessment of new information - Includes coverage of groundbreaking areas, including the artificial LDL particle, the development of a new anti-erectile dysfunction agent, a vaccine for atherosclerosis, coronary calcification associated with red wine, and the interplay of endoplasmic reticulum/oxidative stress - Explores the genetic features of endothelium and the interaction between basic knowledge and clinical syndromes

Biofilms are complex and dynamic communities of surface-attached microorganisms held together by a self-produced extracellular polymeric matrix, forming a highly hydrated structure. It is known that there is considerable heterogeneity within biofilms with respect to local environments, which may result in spatial and temporal patterns of gene expression. Advances in Medicine and Biology. Volume 132 begins by discussing the use of GFP to explore these microbial communities, presenting the most recent developments associated with GFP variants and novel applications of this molecule in biofilm research. Next, the authors discuss the fibrinolytic and its important role in reproduction. Plasminogen Activator Inhibitor-1 (PAI-1) is one of the primary regulators of thefibrinolytic system and is expressed in various cells including ovarian granulosa and theca cells, endometrial cells and trophoblasts. This overview provides the current knowledge on the role of PAI-1 and PAI-1 gene mutations in reproduction. Green fluorescent protein (GFP) is a bio-luminous fluorescent phosphoprotein which was originally isolated from the luminous organ of the jellyfish Aequorea Victoria. At the molecular level, it is composed of 238 amino acids with an approximate molecular weight of about 27 kDa. The authors discuss the role of GFP in animal diagnostic technologies, molecular tracking techniques using GFP as fusion tags in studying protein–protein interactions and real time monitoring of host pathogen interactions. In the authors'Immunoallergology Department, a recent study of 64 CSU patients treated with omalizumab provided pertinent information. Overall, the patients had a reduction of the UAS7 score of 5.82% per omalizumab administration (pOa) and of the DLQI score of 6.69% pOa (data not published). However, when patients were divided according to their baseline serum total IgE levels (STIgE), patients with higher STIgE had a much faster response to omalizumab. The results of this study are discussed in detail. The subsequent chapter aims to explore the diagnosis and management of gastrointestinal stromal tumours (GISTs) that arise from the small bowel in both metastatic and non-metastatic disease. GISTs account for two per cent of all neoplasia of the gastrointestinal tract. They represent the most common GI mesenchymal tumour with a worldwide incidence of 11-15 per million and a median age of presentation of 55-60 years. Diabetes insipidus (DI) is examined as one of the major clinical syndromes characterized by the excretion of copious volumes of diluted urine (polyuria) together with persistent intake of abnormally large volumes of fluid (polydipsia). Investigation of the chronological changes of hyper intensity (HI) distribution over the pituitary stalk and the posterior lobe after transsphenoidal surgery on MR images might enable to predict how frequently postoperative diabetes insipidus occurs and how long it persists, and to elucidate an underlying mechanism for the appearance of the HI in the pituitary stalk. In the following chapter, the authors discuss salient aspects of central nervous system effects of methionine and methionine metabolites in relation to behavioural, neurochemical and possible structural alterations. The possibility of the evolution of conventionally-approved clinical applications of oral methionine, and the potential limitations to its utilisation in such capacity are also considered. Later, this collection considers the functions of Gamma-Aminobutyric acid (GABA) in pharmacology and diseases. The authors aim to address what GABA is, how GABA reacts, and what GABA-related diseases and agents exist. GABA is the principal inhibitory neurotransmitter of the vertebrate central nervous system, acting at inhibitory synapses in the brain. In the concluding chapter, the authors address how gabapentin, a synthetic analog of GABA, may be an effective analgesic used to treat different types of neuropathic pain syndromes, includi

In this compilation, the authors open with a discussion on lectins, carbohydrate-binding proteins which are widely present in living organisms and participate in molecular recognition and intracellular functions. Due to their carbohydrate specificity, lectins can be employed as an analytical tool to study glycan structures on glycoconjugates. Plant lectins have also been used to study glycosylation pattern of animal glycoproteins. The first chapter includes a brief review on lectins, a summary of the general information on glycoconjugate, a review on lectin-affinity techniques and their potential, as well as perspectives of the employment of lectins in the estimation of the glycosylation pattern of glycoconjugates. Next, the authors discuss the cytokine interleukin-7 and its many diverse and important functions in the development and maintenance of immune cells. For haematopoiesis, depending on particular cell type, IL-7 is important for cell survival, proliferation and differentiation. The cytokine's receptor is expressed by early progenitors of B, T lymphocytes and Innate Lymphoid Cells, and IL-7 signaling is critical for the generation of these cells. The authors go on to examine enzyme therapy as a modern way of providing better protection for people with coeliac disease and sensitivity to gluten who have been placed solely on a lifelong gluten-free diet. By itself, the gluten-free diet is not always fully protective of the small intestine because small amounts of gluten can be present from contamination and the failure to recognize “hidden gluten” in food. This chapter explains how certain supplements are able to help those with gluten sensitivity overcome the harmful effects of gluten and reduce the worry about contamination of their food and the lack of knowledge about its gluten content. These supplements represent an important development of the gluten-free diet and will assist in patient management to ensure that patients remain free from the effects of gluten. Later, adrenergic urticarial, a well-defined-yet-neglected variant of urticarial, is discussed. It is characterized by a peculiar clinical picture, with small hives surrounded by white haloes due to local vasoconstriction. Lastly, the authors discuss how abnormalities in physical properties of the cell membranes may be strongly linked to cerebro- and cardiovascular diseases. Recent evidence indicates that increased plasma levels of tumor necrosis factor-a (TNF-a), an inflammatory cytokine, may actively participate in the pathophysiology of endothelial dysfunction, hypertension and other circulatory disorders. The present study was performed to investigate the possible relationships among plasma TNF-a, asymmetric dimethylarginine and membrane fluidity in hypertensive and normotensive subjects using an electron spin resonance (ESR)-spectrometry.

Iatrogenesis is the occurrence of untoward effects resulting from actions of health care providers, including medical errors, medical malpractice, practicing beyond one's expertise, adverse effects of medication, unnecessary treatment, inappropriate screenings, and surgical errors. This is a huge public health issue: tens to hundreds of thousands of deaths are attributed to iatrogenic causes each year in the U.S., and vulnerable populations such as the elderly and minorities are particularly susceptible. Edited by two renowned cardiology experts, Iatrogenicity: Causes and Consequences of Iatrogenesis in Cardiovascular Medicine addresses both the iatrogenicity that arises with cardiovascular interventions, as well as non-cardiovascular interventions that result in adverse consequences on the cardiovascular system. The book aims to achieve three things: to summarize the available information on this topic in a single high-yield volume; to highlight the human and financial cost of iatrogenesis; and to describe and propose potential interventions to ameliorate the effects of iatrogenesis. This accessible book is a practical reference for any practicing physician who sees patients with cardiovascular issues..