Search

With the increasing incidence of Type 2 diabetes in the adult population and the realization that this is a vascular disease and a major coronary risk factor, Professor Betteridge has chosen fifty diabetologists to contribute a case which has had an effect on their clinical practice. Both Types 1 and 2 diabetes are included, along with other forms of diabetes, eg gestational. Each case is presented in the same format. The various cases are informative and educational and should provide the reader with a sounder knowledge of patient and disease types.

Fibrinolysis in Disease reviews the state of the art of basic and clinical aspects of the fibrinolytic enzyme system. The text, authored by outstanding and internationally known investigators, is presented in two books.The Malignant Process, Interventions in Thrombogenic Mechanisms, and Novel Treatment Modalities discusses the molecular biology of the system's key components and their fundamental roles in a variety of thrombotic and metabolic disorders. Molecular and Hemovascular Aspects of Fybrinolysis presents the latest findings and concepts of the association between plasminogen activator (u-PA) overexpression and abnormal growth regulation in a variety of solid tumors and in leukemia. One chapter deals with various successful interventions in thrombogenic mechanisms, ranging from exercise and diet to anticoagulants and direct and indirect thrombolytic agents. It concludes with a projection of exciting, novel treatment modalities in thrombotic and malignant diseases.

Het tandheelkundig jaar 2009 biedt een overzicht van de meest recente ontwikkelingen in de tandheelkunde. Een breed scala aan onderwerpen komt aan bod, beschreven door een keur van gezaghebbende Nederlandse en Vlaamse auteurs. Een greep uit de onderwerpen: De behandeling van halitose, Behandeling van mucositis, Overzicht implantaatsystemen, Retentie is geen evidentie, Tandheelkundige afwijkingen in het Ehlers–Danlos syndroom, Mondzorg bij reumatoïde artritis.

Predictive, preventive and personalized medicine offers great promise for the future practice of medicine. Essential components of this approach include well-organized population screening protocols utilizing novel diagnostic biomarkers of disease states, targeted prevention of common human pathologies, optimal treatment planning and personalized medicine thereby resulting in substantial improvement of the quality of life. This approach also offers the advantage of delivering care at potentially reduced costs to the population at large thereby addressing social and ethical issues related to access to and affordability of health care. Consequently, conventional medicine and new branches of biomedicine are currently challenging many issue-related questions: Should molecular diagnostic approaches be considered complementary or substitutive measures to conventional approaches? How reliable are biomarkers for any given pathology? How to distinguish between the highly predictive power of innovation and quackery in diagnostics? How to overcome currently well-recognizable (inter)national barriers in knowledge transfer? How to correctly educate the new generation of experts in bio- and predictive medicine? The book addresses these highly relevant issues and provides some clues for plausible solutions. The information presented in this book emphasizes the necessity of individualized patient treatment and provides compelling reasons as to why “across-the-board” treatment is not warranted. Application of nutritional proteomics results in individualized optimal diet and may potentially restrict the epidemic scale of type 2 Diabetes mellitus. A broad distribution and a routine clinical utilization of these advanced technological approaches could enable a significant portion of the population to reach the 100-year age limit yet remaining vibrant in excellent physical and mental health and as actively contributing members of society. The examples given in the book are based on well-recognized expertise, scientific publications and international patents. A panel of leading world experts and authorities of the international issue-related associations have contributed to the book by addressing relevant issues and topics such as model-based patient-care and individualized therapy-planning, reproductive medicine and postnatal diagnostics, early/predictive diagnosis and optimized treatment of cancer as well as the most frequent neurodegenerative disorders.

A classic nephrology reference for over 20 years, Seldin & Giebisch's The Kidney, is the acknowledged authority on renal physiology and pathophysiology. The fourth edition follows the changed focus of nephrology research to the study of how individual molecules work together to affect cellular and organ function, emphasizing the mechanisms of disease. With over 40 new chapters and over 1000 illustrations, this edition offers the most in-depth discussion anywhere of the physiologic and pathophysiologic processes of renal disease. Comprehensive, authoritative coverage progresses from molecular biology and cell physiology to clinical issues regarding renal function and dysfunction. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin & Giebisch's The Kidney is your number one source for information.• Offers the most comprehensive coverage of fluid and electrolyte regulation and dysregulation in 51 completely revised chapters unlike Brenner & Rector's The Kidney which devotes only 7 chapters to this topic.• Includes 3 sections, 31 chapters, devoted to regulation and disorders of acid-base homeostasis, and epithelial and nonepithelial transport regulation. Brenner & Rector's only devotes 5 chapters to these topics.• Previous three editions edited by Donald Seldin and Gerhard Giebisch, world renowned names in nephrology. The title for the fourth edition has been changed to reflect their considerable work on previous editions and they have also written the forward for this edition. • Over 20 million adults over age 20 have chronic kidney disease with the number of people diagnosed doubling each decade making it America's ninth leading cause of death.

Now in its sixth edition, The Kidney and Hypertension in Diabetes Mellitus retains its position as the comprehensive resource for information on diabetic kidney disease. The book covers all aspects of renal involvement in diabetes and incorporates information from important publications and new trials conducted during the last three years. The new

Developed through the collaboration of leading experts, Management of Diabetic Nephropathy provides background information on diabetes mellitus and nephropathy as well as a description of the genetic basis and factors causing progression of this disease. The book reviews the various therapeutic options at all stages of renal disease from mild to en

This state-of-the-art reference details current and effective symptom-specific strategies for the diagnosis and management of diabetic patients-emphasizing the exploration of therapeutic options available for the treatment of accelerated coronary complications associated with diabetes.Addresses the pathophysiology underlying advanced heart

Responding to the rising number of ESRD patients and the increasing importance of dialysis care and management, Complications of Dialysis provides a comprehensive, multidisciplinary perspective on the latest therapy options-addressing complications that may arise from dialysis and utilizing the patient-, technique-, and relationship-oriented approa