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Genodermatoses are often considered rare diseases seldom seen by practicing clinicians, but as a result, professionals often have little experience or confidence with their diagnosis when they are called upon for a clinical case.This text presents a comprehensive illustrated overview of almost 200 inherited diseases of the skin, hair, and nails. Examples have been expanded, with new images added to provide clear examples, alongside coherent and comprehensive explanations to enable clinicians to easily identify and source relevant information. This resource encompasses a varied range of skin diseases, providing accessible and in-depth information to help familiarise clinicians. The entry for each disease provides background, followed by common characterisations, manifestations, laboratory findings, genetics, cutaneous and extracutaneous findings, differential diagnosis, an overview of complications and recommended follow-ups.Authored by dermatologists and geneticists, this is an atlas of scientific research which updates established information with current studies and references. In its third edition, this text becomes an invaluable resource for dermatologists and pediatricians.

This title provides a practically applicable guide to the use of immunomodulators and biologics to treat cutaneous diseases. Chapters cover the mechanisms, applications and safety concerns pertaining to the latest systemic therapies. Extensive guidance is provided on how to design lab monitoring schedules, manage patient follow-up visits, develop tapering plans and assess adverse outcomes. The book also reviews how to initiate off-label applications and establish methods of matching mechanisms for a range of diseases to the mechanisms of the available therapies. The latest updates in the development and utility of systemic immunomodulators, biologics and JAK Inhibitors from clinical trials and updated guidelines are also discussed. Immunomodulators and Biologics in Dermatologic Treatment comprehensively describes the use of a range of systemic therapies for immunomodulation in dermatology and how best to incorporate these into practice. It therefore represents a valuable resource for novice readers and experienced dermatologists involved in the management of these patients.

This volume contains nine chapters that detail advances in health and disease. Chapter One provides an overview of stress and mental health problems among students in Japan during the COVID-19 pandemic. Chapter Two addresses general aspects of allergy development and, as a model, structural studies for an essential group of allergenic proteins, the 2S albumins. Chapter Three reviews recent studies on the role of inflammatory mediators in the pathogenesis of the most common diseases of the oral cavity. Chapter Four emphasizes and sheds light on the critical role of Interleukin-17 as a mediator in the pathogenesis of and potential target for the treatment of inflammatory arthritis. Chapter Five focuses on the application of physical and chemical principles to better understand and treat xerosis cutis (dry skin). Chapter Six displays that game theory provides a suitable framework to model the intensive care unit cost and study the cooperation between clinical units in a hospital. Chapter Seven examines personality theories that have dealt with anxiety. Chapter Eight discusses the Markov model. Lastly, Chapter Nine provides an updated report of the employment of induced pluripotent stem cells as a model to study adverse drug reactions.

This comprehensive atlas illustrates the important relationship between periodontal and systemic health and disease with a wealth of superb illustrations. The periodontium as a part of the oral tissues is of great interest to dentists and its importance extends beyond local disorders to a wide range of conditions that may affect periodontal health. The atlas covers both local and systemic disorders including inflammatory diseases, developmental disorders, metabolic disorders, endocrine disorders, cancer and a vast number of other diseases, that may present with gingival or periodontal lesions. Now in its 2nd edition, Periodontal Manifestations of Local and Systemic Diseases helps periodontists, oral medicine specialists, general dentists, and dental students to diagnose and manage patients with complex medical problems. The book is unique because no other books specifically focused on the periodontal manifestations of oral and systemic diseases have been availablein this form. Nineteen years after the first edition the book has been almost entirely rewritten, expanded and updated. Over 50% of the pictorial material has been renewed and enriched with high quality color images. The book is written by a team of experienced experts and will be a valuable resource for the community.

This book is a volume of eight collected chapters on advances in the sciences of health and disease. Chapter One examines the properties of regulatory peptides and their mechanisms of effect on integrative brain activity. Chapter Two reviews the role of inflammatory cytokines in the pathogenesis of rheumatoid arthritis and novel therapeutic targets. Chapter Three provides insight into Tnbs induced ulcerative colitis through the animal model, giving a wide ranging overview of the etiology, pathogenesis, clinical course and pathological features. Chapter Four is a broad overview of issues related to antimicrobial drugs. Chapter Five looks at alternative pharmaceutical options that are, eponymously,'better than Xanax.'Chapters Six and Seven are overviews of overweightness and obesity amongst Saudi and Bahraini adolescents, respectively. Finally, Chapter Eight is a review of muscarinic cholinergic receptor antagonism as a potential method of treating major depressive disorder.

Encyclopedia of Respiratory Medicine, Second Edition, Six Volume Set explores the key processes of lung diseases and their diagnosis and management. The book dissects the molecular and cellular biology, physiology and immunology that underpin normal lung function, along with the aberrations that occur in respiratory diseases, from common disorders such as asthma and COPD to rarer lung diseases such as cystic fibrosis, interstitial lung diseases and pulmonary hypertension. Written in at a time when the globe is in the grip of respiratory pandemic, lung disease has never been so prominent in the public and political conscious. This new edition will provide new researchers in respiratory medicine with a solid foundation in unfamiliar topics and will update more experienced researchers seeking to step outside their core areas of research to put their work into a broader context. - Presents a'one-stop'resource covering the entire scope of modern respiratory medicine - Brings together a truly global collaboration of some of the most authoritative voices in respiratory medicine - Provides chapters that are concise and accessible, with an authoritative introduction for non-specialists, as well as up-to-date, foundational content for those familiar with the field - Includes multimedia-rich content, including hundreds of clear and helpful illustrations that can be used as teaching aids

This acclaimed core text in Dermatology now returns in a thoroughly revised and refocused format. Its clear structuring will enable all readers to find quickly what they need to know and to see how each part fits into the whole, offering a consistent guide for residents wanting a reliable revision aid for the core topics in Dermatology and for physicians in other disciplines interested in individual topics (particularly family physicians specializing in the diagnosis of skin cancer).

Immunology: An Illustrated Outline is both a guide to the essential principles of immunology and a concise dictionary of immunological terms. The book can be used to consolidate understanding in preparation for course exams and medical licensing exams, or as a refresher when immunology is encountered in related life sciences, such as microbiology, virology, and zoology.The book is organized into five sections that represent the major topics in basic and clinical immunology. The Sixth Edition has been comprehensively revised to highlight the latest understanding of the field, particularly in the areas of innate immune defenses and antibody-based therapeutics. Concise explanations of immunological terms Full-color illustrations and micrographs to reinforce the text Each topic is set out in single- or double-page spreads Tables collate and summarize detailed information

This book focusses on the clinical aspects and management of pediatric skin disorders, especially seen in darker skin types. It includes unique conditions that the authors have encountered in their lifetime with their independent observations and approach to management. Original high-quality images are used to illustrate most dermatoses described in the book enabling a strong visual impression of the discussed diseases. It hopes to provide readers with a blend of evidence and experience based pediatric dermatology. This book aims to be a hands-on manual that can be referred to during a busy practice as it discusses the practical approach to dermatoses. Key Features Focusses on darker skin types. Examines unusual presentations with detailed clinical features. Discusses the ways to differentiate between similar-appearing diseases. Explores approaches to therapy, especially in resource-poor settings. Covers topics with high quality illustrations.

Von chronisch entzündlich-rheumatischen Erkrankungen sind bundesweit ca. 20.000 Kinder und Jugendliche bis 18 Jahre betroffen. Unterschieden werden die juvenile Arthritis, die Kollagenosen, die Vaskulitiden und andere immunvermittelte Erkrankungen (z.B. nicht-bakteriell bedingte Knochenentzündungen). Dieses Buch bietet eine kompakte und praxisorientierte Anleitung zu Diagnostik und Therapie von chronisch entzündlich-rheumatischen Erkrankungen im Kindes- und Jugendalter. Ebenso werden wichtige differentialdiagnostische Querverweise erteilt. Aktuelles Wissen von Autoren mit langjähriger praktischer Erfahrung.

‘Dermatological Emergencies'aims to cover aspects of situations and their management when they present in a Dermatology setup. This includes severe drug reactions, bullous disorders, erythroderma, infections, vasculitis and systemic emergencies presenting with skin signs. This book guides the reader to recognize such emergencies, helps to approach the initial phase of management, identifies the investigations, thus leading to a holistic management of the scene. Case scenarios are used in all chapters with logical flow of text, flowcharts, algorithms and representative clinical and laboratory images for better understanding of the readers. Key Features Details all dermatological emergencies Discusses manifestation of these emergencies with unique algorithms and flowcharts Examines case scenarios for first-hand experience Consists of Do's and Don'ts for effective management of cases Uses high quality clinical images for clarity

This compilation opens with a review of the structure and life cycle of neuraminidase in influenza A, and also discusses the method of developing neuraminidase inhibitors derived from natural products and peptides. Following this, the authors describe the different uses of chlorhexidine in the medical field, focusing on dental use. Particularly, the authors discuss its: properties, chemistry, forms of presentation, substantivity and cytotoxicity; uses in dentistry: cariology, periodontology, oral surgery and endodontics. Additionally, the authors discuss rufinamide, a novel triazole derivative which differs from commercial antiepileptic drugs. It is used as an adjunctive medicine in children, adults and the elder population, and administered orally. One study discusses antiviral treatment for the avian influenza A virus using neuraminidase inhibitors such as oseltamivir and zanamivir. Although both inhibitors show therapeutic and prophylactic activities against the H5N1 strains, it is proposed that treatment should be further developed in order to increase the efficiency of the inhibitors against the strains. Angiogenesis or neovascularization is a global term which indicates the physiological process involving the sprouting of new blood vessels from the pre-existing ones. The development of new blood vessels from differentiating endothelial cells is called vasculogenesis. This collection addresses how these processes are vital for tissue development and wound healing in damaged tissues. The spectrum of spondyloarthritides with inflammatory bowel disease and enteropathic arthritis is examined in an effort to give the reader an insight into the risk factors, treatment and prognosis of this clinically challenging rheumatic disease. Later, the principles of optical coherence tomography-guided femtosecond laser cataract surgery are explored. The combination of femtosecond laser surgery and optical coherence tomography imaging simultaneously guides the development of next-generation femtosecond surgical lasers in cataract surgery and explores femtosecond-laser surgical strategies. The authors present a novel colorimetric method for the assay of XI using a reducing monosaccharide determination. The test solution was mixed with 20-fold volume of the 50 mM Na2SiO3, 600 mM Na2MoO4, and 0.95 M HCl aqueous solution (pH 4.5), in which a yellow molybdosilicate species was formed. The penultimate chapter introduces the origin, preparation, applications of Taiyi Shenzhen (Taiyi Moxa Stick Moxibustion), and reviews the relevant research in the past ten years. The concluding study focuses on the daily foraging of honeybees, which is one of the most well-organized social behaviors that exist among social insects. Honeybees are extensively used model animals in behavioral studies for understanding the time-space learning, landmark use and concept of learning.

Skin Tissue Models provides a translational link for biomedical researchers on the interdisciplinary approaches to skin regeneration. As the skin is the largest organ in the body, engineered substitutes have critical medical application to patients with disease and injury – from burn wounds and surgical scars, to vitiligo, psoriasis and even plastic surgery. This volume offers readers preliminary description of the normal structure and function of mammalian skin, exposure to clinical problems and disease, coverage of potential therapeutic molecules and testing, skin substitutes, models as study platforms of skin biology and emerging technologies. The editors have created a table of contents which frames the relevance of skin tissue models for researchers as platforms to study skin biology and therapeutic approaches for different skin diseases, for clinicians as tissue substitutes, and for cosmetic and pharmaceutical industries as alternative test substrates that can replace animal models. - Offers descriptions of the normal structure/function of mammalian skin, exposure to clinical problems, and more - Presents coverage of skin diseases (cancer, genodermatoses, vitiligo and psoriasis) that extends to clinical requirements and skin diseases in vitro models - Addresses legal requirements and ethical concerns in drugs and cosmetics in vitro testing - Edited and authored by internationally renowned group of researchers, presenting the broadest coverage possible

Biomechanics applies the laws and techniques of mechanics in the study of biological systems and related phenomena. Biomechanics uses mathematical and computational tools such as model construction of musclo-skeletal system, body fluid circulation, to aid medical diagnosis, therapeutics and surgery planning, designing of prostheses and implants or in tissue engineering. Present book targets specific topics pertaining to the biomechanics of soft tissues. Subjects addressed includes solids and multi-species mixtures as open systems: a continuum mechanics perspective; electro-chemo-mechanical couplings: tissues with a fixed electric charge and growth of biological tissues.

The new edition of a concise yet thorough illustrated review of the diagnosis and treatment of many forms of psoriasis now includes the many new therapies available and in development, as well as more material on psoriasis as a systemic disease and on comorbidities. This will be of interest to all dermatologists in training and practice, as well as primary care physicians.

The Eye: Basic Sciences in Practice provides highly accessible, concise coverage of all the essential basic science required by today's ophthalmologists and optometrists in training. It is also essential reading for those embarking on a career in visual and ophthalmic science, as well as an invaluable, current refresher for the range of practitioners working in this area. This new fourth edition has now been fully revised and updated in line with current curricula, key research developments and clinical best practice. It succinctly incorporates the massive strides being made by genetics and functional genomics based on the Human Genome Project, the new understanding of how the microbiome affects all aspects of immunology, the remarkable progress in imaging technology now applied to anatomy and neurophysiology, as well as exciting new molecular and other diagnostic methodologies now being used in microbiology and pathology. All this and more collectively brings a wealth of new knowledge to students and practitioners in the fields of ophthalmology and visual science. - The only all-embracing textbook of basic science suitable for trainee ophthalmologists, optometrists and vison scientists – other books concentrate on the individual areas such as anatomy. - Attractive page design with clear, colour diagrams and text boxes make this a much more accessible book to learn from than many postgraduate textbooks. - Presents in a readable form an account of all the basic sciences necessary for an understanding of the eye – anatomy, embryology, genetics, biochemistry, physiology, pharmacology, immunology, microbiology and infection and pathology. - More on molecular pathology. - Thorough updating of the sections on pathology, immunology, pharmacology and immunology. - Revision of all other chapters. - More colour illustrations - Comes with complete electronic version

Diagnosing a genetic skin disease can sometimes be a difficult task for a dermatologist. This is especially true for genodermatoses-generally considered rare diseases seldom seen by practicing clinicians. As a result, professionals often have little experience with their diagnosis. The Atlas of Genodermatoses presents a unique collection of such ca

En parfaite conformité avec le nouveau programme de DFASM, cet ouvrage aborde les connaissances fondamentales en dermatologie. Il comprend deux parties : - une partie Connaissances qui aborde tous les items pour lesquels la dermatologie est concernée : chaque chapitre comporte le numéro de l'item et de l'UE concernés et commence systématiquement par un rappel des objectifs pédagogiques puis développe la thématique, étayée de points clés, de notions à retenir, de tableaux, de figures et de photographies en couleur ; - une partie Entraînement qui propose des cas cliniques commentés (correspondant aux modalités des ECN jusqu'en 2015) et des cas cliniques QRM (sur le modèle des dossiers progressifs) avec grilles de correction, offrant un véritable outil d'auto-évaluation. Cette 6e édition est une remise à jour complète de l'ensemble des données au regard des avancées médicales, en conformité avec le nouveau programme et les nouvelles épreuves. Elle propose par ailleurs des compléments accessibles sur un site internet et par flashcodes. Fidèle à l'esprit des précédentes éditions, l'ouvrage s'inscrit dans la collection Les référentiels des Collèges, dont le format et la maquette en quadrichromie offrent une clarté de lecture et facilitent la compréhension et la mémorisation..

Edited by an expert editorial team from leading dermatology centers, this set consists of two books: Mild to Moderate Psoriasis, Third Edition and Moderate to Severe Psoriasis, Fourth Edition. Using a practical and problem-focused approach, these updated texts equip dermatologists, family practitioners, and internists with a state-of-the-art guide to the clinical management of all forms of psoriasis. The set provides up-to-date treatment strategies for optimum patient management.

Written by experts in the dermatology field, this new fourth edition of Moderate-to-Severe Psoriasis discusses the current use of biologics and other pharmacologic and phototherapy treatments for moderate-to-severe psoriasis. Illustrated with high quality color figures, this standalone text emphasizes safe and effective treatments for the psoriasis