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Rapid advances in our understanding of the etiopathogenesis of the inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis, and how best to treat them, call for a substantial revision and update of ‘Fast Facts: Inflammatory Bowel Disease'. In this new seventh edition, we explore advances in microbiome science which have linked specific microbes with different stages of disease. We discuss current thinking on how best to use immunomodulatory and biological drugs, alone or in combination, along with newly introduced and imminent therapies. This book is aimed at non-specialist doctors (particularly primary care providers and hospital doctors in training), nurses, stoma therapists, dietitians, psychologists, counselors, social workers, and other professionals involved in the care of patients with IBD.

The gold standard in gastrointestinal pathology textbooks returns More than 34 million Americans suffer from pathologies of the digestive system, with over 20 million of these disorders chronic. Treatment of these patients is a complex multidisciplinary area of clinical medicine, drawing upon expertise not only from specialist gastroenterologists but also pathologists, immunologists, endoscopists, and more. Morson & Dawson's Gastrointestinal Pathology has long set the standard for pathology textbooks, with its distinctive balance of clinical gastroenterology and pathology. Now fully updated to reflect the latest research in this vital field of medicine, it promises to bring this subject to a new generation of clinicians and pathologists worldwide. Readers of the sixth edition of Morson and Dawson's Gastrointestinal Pathology will also find: Contemporary recommendations and guidelines for getting the most out of every pathology specimen and producing the best possible report for managing the patientDiscussions of the evolving applications of immunohistochemistry and in situ hybridisationA completely new chapter on lymphoid and other tumours of the large intestine Morson & Dawson's Gastrointestinal Pathology is ideal for gastrointestinal pathologists, general pathologists, gastroenterologists, and any clinicians who work with or in gastrointestinal practice.

Ulcerative Colitis: The Complete Guide to Medical Management serves as the definitive source for medical management of ulcerative colitis (UC).Dr. Gary R. Lichtenstein, along with Dr. Ellen J. Scherl, have collaborated with over 60 experts from around the world to provide gastroenterologists and those in training with the necessary information to successfully manage the patient with ulcerative colitis. Sections Include:• Generalo The role of the FDA in drug development; pediatric considerations; disease modifiers; and more• Medicationso Antibiotic use in treatment of UC; oral novel biological therapies for UC; calcineurin inhibitors use in UC; novel biologic and non-biologic therapy for UC; and more• Specific Clinical Presentationso Medical management of toxic megacolon; management of extraintestinal manifestations; medical therapy of left-sided UC; use of prebiotics and probiotics; maintenance of remission; and moreFeatures:• Color images, graphs, and tables• Extensive index that includes cross-referencing to Crohn's Disease: The Complete Guide to Medical Management• Comprehensive references at the end of each chapterOrganized into an easy-to-reference format, Ulcerative Colitis: The Complete Guide to Medical Management threads theory into practice and provides gastroenterology professionals with the most comprehensive information available. The other side of inflammatory bowel disease is covered in Drs. Gary R. Lichtenstein and Ellen J. Scherl's Crohn's Disease: The Complete Guide to Medical Management. All gastroenterologists will find both books to be essential for future practice in the treatment and care of their patients with either Crohn's disease or ulcerative colitis, as well as in the overall management of those with inflammatory bowel disease.

This book now published in its fully updated second edition comprehensively summarizes the current state of knowledge on malignancies of the gastrointestinal tract and highlights the latest efforts in multimodality treatment options before and after surgery, important ongoing trials as well as future areas of investigation. Dedicated organ-based chapters evaluate current treatments and management and provide information on incidence, etiology and biological characteristics. The state of the art in the radiologic and endoscopic staging of gastrointestinal malignancies is described, and guidance is offered on the role of interventional radiology and interventional gastroenterology in the treatment of these challenging tumors. In addition, the book explores novel and evolving treatments, including Immunotherapy, personalized systemic therapy and minimally invasive surgical and radiology techniques, and addresses patient-reported outcomes and survivorship challenges. It will be of benefit to all surgeons, oncologists and other specialists who treat these malignancies, as well as to trainees looking to increase their understanding of the field.

Physicians treating patients with Inflammatory Bowel Disease (IBD) often face challenges due to the disease itself, associated conditions, and systemic effects. Recently, new medications have been introduced that allow for more aggressive and effective treatment of IBD. With these medications come the risks of adverse side effects, and physicians must vigilantly monitor for any complications. Drs. Miguel D. Regueiro and Jason Swoger have created a unique, user-friendly book that describes how to prevent, recognize, and manage complications encountered in the care of patients with IBD. Clinical Challenges and Complications of IBD aims to provide practical and clinically oriented information to assist physicians with commonly encountered complications of the natural history of IBD, extraintestinal manifestations of IBD, general health and metabolic complications of IBD, and complications arising from both the medical and surgical treatments of IBD. Formatted to allow for quick access of the information, Clinical Challenges and Complications of IBD is organized into sections that allow physicians to both identify potential pitfalls in treatment, as well as focus on health maintenance and specific challenges, including pregnancy, nutrition, and psychological issues. Clinical pearls will be emphasized and each chapter will provide a bulleted summary, along with suggestions for future reading.Clinical Challenges and Complications of IBD is an invaluable guide for gastroenterologists, nurse practitioners, physician assistants, and gastroenterology trainees as it is a one-of-a-kind resource for recognizing and dealing with the challenges and complications in patients with IBD.

There have been many advances in the diagnosis and treatment of cancer, but it is still a feared disease with a lot of work left to be done. The importance of gastrointestinal cancer as a frequently occurring disease goes without saying. It accounts for half of human cancer cases but differs from other forms of cancer. Complete prevention is possible through proper treatment of precancerous lesions. There is still no comprehensive book about prevention, early diagnosis, and proper treatment of precancerous lesions and new developed diagnostic modality, and treatment such as endoscopic treatment and minimal invasive surgery and chemotherapy and immunotherapy. Also, this book will contain conservative treatment methods for patients suffering from diverse complications. There will be plentiful clinical cases including endoscopic findings, radiologic images, pathology and treatment outcome in this book. For these reasons, this book will give very valuable information to many gastroenterologists, oncologists, surgeons and general physicians.

YAMADA'S Textbook of Gastroenterology For over 25 years, Yamada's Textbook of Gastroenterology has been the most comprehensive gastroenterology reference book, combining an encyclopedic basic science approach to GI and liver disease with the latest clinical thinking, especially in diagnostic and therapeutic developments. It is universally respected across the globe. The original outstanding editorial team was led by Tadataka Yamada, MD, one of the world's leading figures in GI research. This seventh edition of the Textbook features a new set of Editors-in-Chief and a new team of Associate Editors. This new editorial team has made substantial changes and updates to the Textbook, with a greater focus on the human microbiome, obesity, bariatric endoscopy and aging, along with consolidation of many older chapters. Led by Professor Michael Camilleri and Professor Timothy C. Wang, a stellar group of associate editors have once again combined with authors in their respective fields to communicate their vast fund of knowledge and experience to make the 7th edition of this iconic textbook the most comprehensive ever published.

Now fully revised to include recent advances in the field, the third edition of Gastrointestinal and Liver Pathology Pathology, a volume in the Foundations in Diagnostic Pathology series, is an essential foundation text for residents and pathologists. The popular template format makes it easy to use, and new information throughout brings you up to date with what's new in the field, including advances in molecular diagnostic testing and new diagnostic biomarkers. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice.Key features of this practical text include: - A consistent, user-friendly format that explores each entity's clinical features, gross and microscopic findings, ancillary studies, differential diagnoses, and prognostic and therapeutic considerations. - A focus on specific features of selected neoplastic and non-neoplastic entities, including broad and in-depth differential diagnoses. - Clinical information on treatment and prognosis, enabling you to better understand the clinical implications of the diagnosis. - Nearly 1,000 full-color, high-quality illustrations with extensive figure legends, as well as abundant boxes and tables throughout. What's NEW in this edition: - Advances in molecular diagnostic testing and its capabilities and limitations, including targeted/personalized medicine. - New diagnostic biomarkers and their utility in differential diagnosis, newly described variants, and new histologic entities. - The latest TNM staging and WHO classification systems. - New co-editors Drs. Amitabh Srivastava and Daniela S. Allende lead a team of expert, internationally recognized pathologists who keep you up to date with the latest information in the field.

This book is a comprehensive, state-of-the art, definitive reference for the surgical management of Neuroendocrine Tumors (NETs). It provides a practical, clinically useful guide that prioritizes the diagnostic work-up, indications for surgery, surgical principles, and perioperative care of patients with NETs in the context of multi-disciplinary care. Most textbooks on NETs have traditionally focused on patients with advanced disease, highlighting systemic therapies and emerging treatment options. In contrast, this book provides a concise yet comprehensive summary of the surgical management of NETs and serves as an invaluable resource for physicians, fellows, and residents who treat this difficult disease by providing helpful guidelines and up-to-date information on clinical management. Written by experts in the field, Neuroendocrine Tumors includes the most up-to-date clinical information from national and international leaders in their respective disciplines. It not only serves as an invaluable resource for many as they seek to provide the best possible surgical and multidisciplinary cancer care, but also an opportunity to identify new avenues of scientific discovery that may lead to significant advances in the diagnosis and management of NETs.

Inflammatory bowel disease (IBD) comprises two idiopathic chronic relapsing and remitting inflammatory disorders of the gastrointestinal tract: ulcerative colitis and Crohn's disease. Understanding of the etiopathogenesis of IBD, and how best to treat it, continues to advance rapidly and has led to the need for this new edition. Chapter 1 has been substantially revised, emphasizing recent data that indicate how the gut microbiome and its human host may interact to cause IBD in genetically susceptible people. In later chapters, the latest thinking on how best to use immunomodulatory and biological drugs is discussed, along with new sections on recently introduced and imminent therapies. This book is aimed at non-specialist doctors (particularly primary care providers and hospital doctors in training), nurses, stoma therapists, dieticians, psychologists, counselors, social workers and other professionals involved in the care of patients with IBD.

For nearly 50 years, Sleisenger & Fordtran's Gastrointestinal and Liver Disease has been the go-to reference for gastroenterology and hepatology residents, fellows, physicians, and the entire GI caregiving team. Now in a fully revised 11th Edition, this two-volume masterwork brings together the knowledge and expertise of hundreds of global experts who keep you up to date with the newest techniques, technologies, and treatments for every clinical challenge you face in gastroenterology and hepatology. A logical organization, more than 1,100 full-color illustrations, and easy-to-use algorithms ensure that you'll quickly and easily find the information you need. - Features new and expanded discussions of chronic hepatitis B and C, Helicobacter pylori infection, colorectal cancer prevention through screening and surveillance, biologic agents and novel small molecules to treat and prevent recurrences of inflammatory bowel disease (IBD), gastrointestinal immune and autoimmune diseases, and more. - Offers reliable coverage of key topics such as Barrett's esophagus, gut microbiome, enteric microbiota and probiotics, fecal microbiota transplantation, and hepatic, pancreatic, and small bowel transplantation. - Provides more quick-reference algorithms that summarize clinical decision making and practical approaches to patient management. - Employs a consistent, templated, format throughout for quick retrieval of information. - Includes monthly updates online, as well as more than 20 procedural videos. - Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Gastric cancer is one of the most common and potentially lethal gastrointestinal malignancy, but it is now at the forefront of modern oncology due to new discoveries. In recent years, the field of gastric cancer has been transformed by many notable developments in both the diagnostic area and the therapeutic strategies.The main aim of the text is to propose a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for oncologists, pathologists, surgeons and researchers with an interest in gastric cancer. The first chapters will review the interplay between pathogens and especially H. pylori, inflammation, genomic instability, and tumorigenesis. Secondly, an exhaustive overview of the diagnosis of gastric cancer from a clinical/endoscopic and pathologic perspectives will be illustrated. Two specific chapters will deal with tissue and serum biomarkers with an important role in diagnosis as well as prognostic and predictive markers of response to specific therapy. A central section of the book will focus on treatment options available today for patients. Surgery is the cornerstone of treatment for gastric cancer; however, the prognosis of patients with locally advanced disease is still poor even after curative resection. Therefore, in order to improve the prognosis of patients, especially with advanced stage, a multimodal strategy is advisable and is thoroughly addressed in the appropriate section. With the advent of next-generation sequencing and new preclinical model technologies, the genomic landscape of gastric cancer has been delineated and molecular characterizations finalized to novel therapeutic targets of each molecular subtype have been identified. These advances are making it feasible to integrate clinical and phenotype-based diagnostic and therapeutic methods and are described in a dedicated section. The text will conclude with chaptersfocusing on the future direction of gastric cancer research in the precision medicine era: an in-depth analysis of non-coding RNAs and their role in gastric cancer, the impact of immunomodulation/immunotherapy and the perspectives of nano-medicine will be finally proposed to the audience. A brief review of the existing literature addressing the above mentioned topics will be present in each chapter. This text will serve as a useful resource for physicians and researchers dealing with, and interested in, this challenging malignancy. It will provide a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters will be written by experts in their fields and will include the most up to date scientific and clinical information.

This book provides a concise, yet comprehensive overview of cancer risks in patients with inflammatory bowel disease (IBD), as well as the screening modalities used to reduce these risks. Each chapter presents a major malignancy that patients with IBD are at risk from, stemming from the disease itself or from the medications used to treat the disease. Malignancies covered include colorectal cancer, skin cancer, lymphoma, and other cancers. Cancer risk and screening with current and emerging drug therapies are also discussed. Written by experts in the field, Cancer Screening in Inflammatory Bowel Disease: A Guide to Risk Management and Techniques is a valuable resource for gastroenterologists, colorectal surgeons, and primary care physicians who treat and manage patients with inflammatory bowel disease.

Now thoroughly up-to-date, Clinical Gastrointestinal Endoscopy, 3rd Edition, by Drs. Vinay Chandrasekhara, Mouen Khashab, B. Joseph Elmunzer, and V. Raman Muthusamy, ensures that you stay current with the latest technology and techniques in GI endoscopy. An all-new editorial team, newly updated images, and a reorganized format make this reference an easy-to-use source of reliable information on a full range of topics, including anatomy, pathophysiology, and therapeutic management options, in addition to the latest GI procedures and technologies. - Offers state-of-the-art coverage of bariatric surgery, therapeutic EUS, device-assisted enteroscopy, image-guided therapy, intramural endotherapy, and much more. - Features 100 updated videos with author voiceovers, as well as 1,000 revised photographs, endoscopic images, and anatomical drawings. - Provides a fresh perspective and expert guidance from an entirely new editorial team. - Includes many more references per chapter, as well as further references online. - Presents material in a newly restructured, organ-based format for quick reference. - Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

The revised fourth edition of Evidence-Based Gastroenterology and Hepatology continues to provide the most current, evidence-based information for determining the appropriate medical and surgical options for screening for, diagnosing, and treating gastrointestinal conditions. With contributions from an international team of leading experts in the field, the 4th edition includes practical recommendations for the care of individual patients based on the latest scientific evidence.

This book provides a comprehensive and complete overview of biomarkers in clinical practice for inflammatory bowel disease (IBD) bringing together the literature in a clear and concise manner. The book bridges the gap between growing knowledge at the bench and current and future applications of biomarkers in clinical practice. The central structure of the book focuses on prognostic and predictive biomarkers in IBD with an emphasis on the fields of research and scientific techniques (genomics, proteomics and metabonomics) that have led to biomarker discovery and places these biomarkers within a clinical context to help understand their utility in clinical practice.This book will be of use to clinicians who have an interest in using biomarkers in clinical practice as well as clinician researchers and scientists involved in the biomarker research pipeline.The author team comprises experts from around the world in order to bring together the literature in an effort to inform clinicians and researchers about the current state-of-the art in biomarker discovery. It is intended to assist future research efforts and indicate how biomarkers might be best applied to clinical practice both at present and in the future.

The most comprehensive and authoritative reference available today on colorectal surgeryThis revised fourth edition of Gordon and Nivatvongs'Principles and Practice of Surgery for the Colon, Rectum, and Anus edited by David Beck, Steven Wexner, and Janice Rafferty strikes a perfect balance between evidence-based medicine, in-depth details, and clinical pearls. The result is a highly engaging and authoritative tome in the grand tradition of Philip Gordon and Santhat Nivatvongs. Building on the widely acclaimed previous editions'reputation for superb quality and reader-friendliness, the fourth edition includes contributions from an expanded cadre of internationally known experts.Significant advances have been made in this field since the third edition was published. The latest diagnostic modalities are highlighted such as MRI, CT angiography, and enterography. The first section covers essentials such as anatomy, physiology, diagnosis, colonoscopy, and patient management. Sections two through four discuss a full spectrum of anorectal diseases, colorectal disorders, trauma, unexpected challenges, and complications. Among the additions are expanded sections on transanal total mesorectal excision, genetics, personalized medicine,'wait and watch'principles, outpatient management of anorectal surgery, and large bowel obstruction.Key HighlightsThirty-seven chapters cover a wide array of gastrointestinal disorders such as fecal incontinence, ulcerative colitis, Crohn's disease, diverticulitis, carcinomas, and other malignant lesionsA multidisciplinary team approach to rectal cancer encompasses rectal cancer protocol MRI, synoptic reporting, and various neoadjuvant therapy protocolsThe use of cutting-edge approaches including laparoscopy, robotics, hyperbaric oxygen, and radiofrequency tissue remodelingSuperb full-color plates, illustrations, photographs, diagrams, detailed tables, graphics, and surgical videos elucidate underlying disease and managementAs the most comprehensive resource on colorectal surgery available on the market today, this is a must-have for every colon and rectal surgeon – from residents to veteran practitioners.

This revised and updated second edition explains how to analyze endoscopic mucosal biopsies of the ileum and colon. As in the first edition, the diagnosis and follow up of colitis in general and inflammatory bowel diseases in particular is covered and this edition also includes new chapters on ileitis and optimal biopsy procedures. The basic lesions are described using multiple drawings together with an explanatory text and endoscopic and histological photographs. A review of various differential diagnostic issues and types of colitis is also included.Colitis: A Practical Approach to Colon and Ileum Biopsy Interpretation is aimed at general pathologists and pathologists in training and also gastroenterologists to help them understand how a precise diagnosis can be reached.

Pouchitis and Ileal Pouch Disorders: A Multidisciplinary Approach for Diagnosis and Management provides much needed information on the evolution of pouch surgery, pouch surgery techniques, and surgery-associated complications, including inflammatory, functional, neoplastic, and metabolic complications. The book provides information on the anatomy of the pouch, pathogenesis of pouchitis and other pouch disorders, proper diagnostic modalities, and medical, endoscopic and surgical options for those disorders. The information has been compiled from a panel of national and international leading experts in the field, including basic scientists, gastrointestinal (GI) pathologists, GI radiologists, gastroenterologists, and more. - Features never-before-published information and technology from the vast experience of the contributors and editors in diagnosis and medical, endoscopic, and surgical management of pouchitis and other pouch disorders - Contains easy to access recommendations from experts - Provides access to an accompanying website with videos of endoscopic demonstrations of various configurations of the pouch, endoscopic evaluation of pouch disorders, and endoscopic treatment of pouch strictures, fistula, and anastomotic leaks/sinuses

Advances in Endoscopy in Inflammatory Bowel Disease summarizes the recent progress made in endoscopy, an essential tool for the diagnosis and management of IBD. It goes on to provide an introduction of state-of-the-art endoscopic techniques, as well as an atlas of high-quality endoscopic images of IBD and related diseases. Among others, endoscopy is one of the clinical fields in which Asian countries are leading the way in the management of gastrointestinal disorders. As the number of patients with IBD is dramatically increasing in Asia, quality of patient care has been significantly improved. With diagnosis of intestinal Behcet, simple ulcers, and intestinal tuberculosis, which are unique to the Asian countries, this book offers the ideal standard textbook for IBD endoscopy in all Asian counties, while the superior quality of images also makes it a valuable resource for practitioners around the globe. This book will significantly help all physicians, endoscopists and researchers working on GI endoscopy, especially those focusing on IBD, to improve their knowledge of IBD endoscopy.

This brand new updated edition of the most comprehensive reference book on pancreatic disease details the very latest knowledge on genetics and molecular biological background in terms of anatomy, physiology, pathology, and pathophysiology for all known disorders. Included for the first time, are two brand new sections on the key areas of Autoimmune Pancreatitis and Benign Cystic Neoplasms. In addition, this edition is filled with over 500 high-quality illustrations, line drawings, and radiographs that provide a step-by-step approach to all endoscopic techniques and surgical procedures. Each of these images can be downloaded via an online image bank for use in scientific presentations. Every existing chapter in The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery, 3rd Edition has been thoroughly revised and updated to include the many changes in clinical practice since publication of the current edition. The book includes new guidelines for non-surgical and surgical treatment; new molecular biologic pathways to support clinical decision making in targeted treatment of pancreatic cancer; new minimally invasive surgical approaches for pancreatic diseases; and the latest knowledge of neuroendocrine tumors and periampullary tumors. The most encyclopedic book on the pancreas—providing outstanding and clear guidance for the practicing clinician Covers every known pancreatic disorder in detail including its anatomy, physiology, pathology, pathophysiology, diagnosis, and management Completely updated with brand new chapters Over 500 downloadable illustrations An editor and author team of high international repute who present global best-practice The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery, 3rd Edition is an important book for gastroenterologists and gastrointestinal surgeons worldwide.

Os títulos da série MOUNT SINAI Expert Guides fornecem acesso rápido à informação clínica especializada para médicos de diversas áreas terapêuticas. Este, de Gastroenterologia, editado por especialistas renomados da Icahn School of Medicine em Mount Sinai, conta com a contribuição dos principais membros do corpo docente. A fim de garantir a consistência em cada título e na série como um todo, os capítulos seguem uma estrutura única: Problemas comuns no diagnóstico e tratamento; Como prevenir complicações; Algoritmos de diagnóstico e tratamento; Principais ensaios científicos; Conteúdo clínico baseado em evidências; Diretrizes das principais organizações.

The latest edition of this essential text provides a comprehensive overview of the unique pediatric issues of inflammatory bowel disease. Through new and thoroughly revised chapters, the volume features updates regarding pathogenesis, clinic features, and management, with an emphasis on recent understanding of pharmacokinetics and the utilization of cutting edge therapeutic monitoring to maximize efficacy of medical management. The new edition also highlights newer, recently approved drugs, emerging therapies, and the most recent recommendations regarding post-operative management for patients who ultimately require surgery. Written by experts in the field, Pediatric Inflammatory Bowel Disease, Third Edition is a valuable resource for both pediatric and adult gastroenterologists involved in the care of children with inflammatory bowel disease.

The latest edition of this text provides a comprehensive overview of the “natural flow of knowledge” regarding inflammatory bowel disease, with an emphasis on state-of-the art approaches that should be the basis for diagnosis and treatment of most patients. In addition to updated chapters, this volume includes new chapters on such topics as the impending biosimilar revolution, quality of care, and new challenges to previously held beliefs about IBD diagnosis, treatment, and pathogenesis. The book is also one of the first to have a chapter written specifically by and for physician extenders in the training of colleagues and the treatment of patients, which is of increasing importance moving forward in the medical profession. Written by experts in the field, Inflammatory Bowel Disease: Diagnosis and Therapeutics, Third Edition is a valuable resource for physicians, nurses, researchers, and other health care providers interested in the latest cutting-edge knowledge for treating patients with inflammatory bowel disease.

This book examines the biological aspects of bile acid analysis and their clinical applications, providing readers with an overview of cutting-edge discussions on Bile Acid research and diseases. It begins with detailed discussions on the biological aspects of bile acid, with chapters examining bile acid from various perspectives, from its metabolism to its use in therapeutic agents. Subsequent chapters focus on diseases involving bile acid abnormalities, and specific applications are addressed concerning gallstones, cholestatic liver disease, NAFLD/NASH, hepatitis, pancreatitis, esophageal cancer and colon cancer. In keeping with the book's integrated approach, the Editor has gathered a broad range of eminent scholars and practitioners to provide a comprehensive review of modern bile acid research. The book offers clinical physicians, basic researchers and postgraduate students essential insights into cutting-edge research and paves the way for further research.

This new edition is a unique combined resource for physicians and scientists addressing the needs of both groups. In addition to stimulating exchange and collaboration and shortening the path between discovery and application of new knowledge, the book helps clinicians understand new therapeutic concepts from their origins. The volume serves as a comprehensive guide to the current diagnostic modalities, including enhanced imaging techniques such as MRI and CT enterography, virtual colonoscopy, ultrasound, and endomicroscopy, as well as conventional and complex immunomodulatory principles. The latest edition also includes revised chapters from the previous edition, as well as new chapters reflecting current developments in the field. Written by experts in their field, Crohn's Disease and Ulcerative Colitis: From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach, Second Edition is of great value to gastroenterologists, surgeons, internists,pediatricians and gynecologists trainees, as well as all those involved in Crohn's disease, ulcerative colitis, and related autoimmune disorders.

Ulcerative colitis and Crohn's disease, referred to collectively as inflammatory bowel disease (IBD), are chronic debilitating disorders. IBD, particularly Crohn's disease, is increasing everywhere, most notably in the Western world where about 1 in 200 people now has the condition. This highly readable,'zippy'fifth edition of'Fast Facts: Inflammatory Bowel Disease'provides succinct yet thorough information that will aid early recognition of these disorders and their complications, alongside practical holistic management advice. With important emphasis on the doctor–patient relationship and effective multidisciplinary services,'Fast Facts: Inflammatory Bowel Disease'is an invaluable resource for all primary care providers, hospital doctors in training, nurses, stoma therapists, dieticians, psychologists, counselors and social workers; in fact, all health professionals involved in the care of patients with IBD, as well as patients who wish to know more about their condition.

Consult the leading text in the field that delivers the information you need to diagnose and treat pediatric gastrointestinal and liver diseases effectively. In one convenient and comprehensive volume, Drs. Robert Wyllie, Jeffrey S. Hyams, and Marsha Kay provide all the latest details on the most effective new therapies, new drugs, and new techniques in the specialty. In addition, the new two-color design throughout helps you find what you need quickly and easily. Full-color endoscopy images to help improve your visual recognition Definitive guidance from renowned international contributors who share their knowledge and expertise in this complex field Detailed diagrams that accurately illustrate complex concepts and provide at-a-glance recognition of disease processes More than 400 board review-style questions, answers, and rationales New therapies for hepatitis B and C, new drugs for the treatment of inflammatory bowel disease, and an expanded discussion of the newest endoscopic and motility techniques available for pediatric patients The most current information on diagnosing and treating abnormalities of protein, fat, and carbohydrate metabolism New chapters on pancreatic transplantation and liver pathology The latest surgical techniques for children with gastrointestinal conditions

This book comprehensively summarizes the current state of knowledge on malignancies of the gastrointestinal tract. Dedicated organ-based chapters evaluate current treatments and management and provide information on incidence, etiology and biological characteristics. The state of the art in the radiologic and endoscopic staging of gastrointestinal malignancies is described, and guidance is offered on the role of interventional radiology and interventional gastroenterology in the treatment of these challenging tumors. In addition, the book explores novel and evolving treatments, including personalized systemic therapy and minimally invasive surgical and radiology techniques, and addresses patient-reported outcomes and survivorship challenges. It closes by discussing animal models of gastrointestinal malignancies and examining the significance of the Ras superfamily of GTPases. It will be of benefit to all surgeons, oncologists and other specialists who treat these malignancies, as well as to trainees looking to increase their understanding of the field.

Yamada's Textbook of Gastroenterology has for 20 years been the most comprehensive gastroenterology reference book, combining an encyclopaedic basic science approach to GI and liver disease with the latest clinical thinking, especially in diagnostic and therapeutic developments. It is universally respected across the globe.The original outstanding editorial team was led by Tadataka Yamada, MD, one of the world's leading figures in GI research. As in previous editions, the new textbook reflects the collective efforts of the editors and a hugely impressive team of contributors, who are each experts in their specific areas. Now with another world leader in gastroenterology as Editor-in-Chief, Daniel K. Podolsky MD, President and Professor of Internal Medicine at the University of Texas Southwestern Medical Center, together with a stellar group of associate editors, the 6th edition of this iconic textbook has been expanded and enhanced in many ways with new content and technology.

Now in its 10th edition, Sleisenger and Fordtran?s Gastrointestinal and Liver Disease remains your indispensable source for definitive, state-of-the-art answers on every aspect of gastroenterology and hepatology. Overcome your most complex clinical challenges and make optimal use of the newest techniques, technologies, and treatments?with superb guidance from hundreds of world-renowned authorities. Meticulous updates throughout include the latest approaches and improvements in gastrointestinal and liver disease diagnosis and therapy as well as hundreds of images and 35 new procedural videos.'..one of the most valuable clinical resources in the dynamic field of gastroenterology and hepatology.'Reviewed by Brindusa Diaconu on behalf of the Journal of Gastrointestinal and Liver Diseases, July 2015'..an engaging, educational yet clinically orientated textbook which is relevant to modern clinical practice.'Reviewed by Dr Harry Brown on behalf of glycosmedia.com, April 2015'I can personally attest to the remarkable advances that have been made, as I was author of the chapter on eosinophilic gastroenteritis in the second edition of the textbook, and reading the same chapter in the tenth edition underscores the important advances that have been made in our understanding of the molecular basis as well as the pathophysiology of this and related disorders.'Foreword by Norton J. Greenberger, MD Boston, Massachusetts, June 2015 Consult this title on your favorite e-reader. Get the essential gastroenterology information you need from one authoritative source with an outstanding global reputation for excellence. Zero in on the key information you need to know with a consistent, full-color chapter design. Stay up to date with emerging and challenging topics: enteric microbiota and probiotics; fecal microbiota transplantation; Clostridium difficile colitis; and factitious gastrointestinal diseases. Incorporate the latest findings and improvements in care for liver disease patients—from diagnosis and treatment through post-treatment strategies and management of complications. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.

A thorough update is presented by the Guest Editors on the diagnosis, treatment, and management of Barrett's Esophagus. Not only do they address the most pertinent clinical issues like screening, biomarkers, surveillance, therapeutics, and predictors of disease progression but they present state of the art material on therapeutic/treatment modalities like EMR, ESD, and ablative therapy. Further, articles are presented on epidemiology, molecular pathogensis, and cost-analysis studies so that the reader will come away with a comprehensive update on Barrett's Esophagus.

Clinics Collections: Gastrointestinal Diseases draws from Elsevier's robust Clinics Review Articles database to provide multidisciplinary teams, including general practitioners, gastroenterologists, otolaryngologists, oncologists, pathologists, and surgeons, with practical clinical advice and insights on this highly prevalent condition and its comorbidities. Clinics Collections: Gastrointestinal Diseases guides readers on how to apply current primary research findings on gastrointestinal diseases to everyday practice to help overcome challenges and complications, keep up with new and improved treatment methods, and improve patient outcomes. • Areas of focus include gastroesophageal reflux disease, Barrett's esophagus, upper gastrointestinal bleeding, dyspepsia, eosinophilic esophagitis, gastroparesis, dysphagia, esophageal tumor, colon polyps/cancer, constipation, inflammatory bowel disease, gastroenteritis, lower gastrointestinal bleeding, and hemorrhoids. • Each article begins with keywords and key points for immediate access to the most critical information. • Articles are presented in an easy-to-digest and concisely worded format. Elsevier's Clinics Collections provide concise reviews of today's most prevalent conditions and significant medical developments. Other Clinics Collections titles available include Type II Diabetes Mellitus, Asthma, Obesity, Pain Management, Lipid Disorders, and Chronic Obstructive Pulmonary Disease.

Colonoscopy is the bread and butter for endoscopists and advances in the procedure to reduce time, improve efficiency, and prevent errors are very important for this group. The newest advances look at colonoscopy efficiency and a better way to target tissue sampling, which avoids random biopsies and instead looks at ways to predict areas for sampling. The Guest Editors have selected top experts to provide these important updates and they also address current thinking that questions the continued value of colonoscopies as predictors of colon cancer. The issue will be a very popular one, and it needs to be heavily promoted.

This concise book explains how to analyze endoscopic mucosal biopsies of the colon obtained for diagnosis and follow up of colitis in general and inflammatory bowel diseases (ulcerative colitis, Crohn's disease and microscopic colitis) in particular. This is achieved by the presentation of basic lesions in multiple drawings together with an explanatory text and microscopic photographs. The description is completed by a review of various differential diagnostic issues and types of colitis.Colitis: A Practical Approach to Colon Biopsy Interpretation is aimed at general pathologists and pathologists in training and also gastroenterologists to help them understand how a precise diagnosis can be reached.

Mount Sinai Expert Guides: Gastroenterology will provide physicians with an extremely clinical and accessible handbook covering the major GI diseases and symptoms, their diagnosis and clinical management. Perfect as a point-of-care resource on the hospital wards and also as a refresher for board exam preparation, the focus throughout is on providing rapid reference, essential information on each disease to allow for quick, easy browsing and assimilation of the must-know information. All chapters follow a consistent template including the following features: - An opening bottom-line/key points section - Classification, pathogenesis and prevention of disease - Evidence-based diagnosis, including relevant algorithms, laboratory and imaging tests, and potential pitfalls when diagnosing a patient - Disease management including commonly used medications with dosages, when to perform surgery, management algorithms and how to prevent complications - How to manage special populations, ie, in pregnancy, children and the elderly - The very latest evidence-based results, major society guidelines (ASG/ACG/UEGW) and key external sources to consult In addition, the book comes with a companion website housing extra features such as case studies with related questions for self-assessment, key patient advice and ICD codes. Each guide also has its own mobile app available for purchase, allowing you rapid access to the key features wherever you may be. If you specialise in gastroenterology and require a concise, practical guide to the clinical management of GI disease, bought to you by one of world's leading hospitals, then this is the perfect book for you.This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from iTunes, Google Play or the MedHand Store.

This book conjoins the latest advances on the use of endoscopy to diagnose, monitor, and treat patients with inflammatory bowel disease. Chapters include the historical use of rigid sigmoidoscopy, non-interventional imaging procedures, and the correlation of pathology and endoscopic visualization. This is the first book to include individual chapters in gastroenterology, colorectal surgery, and IBD texts, the preeminent role of endoscopic imaging in the management of chronic ulcerative colitis, and Crohn's disease. It also includes chapters on capsule endoscopy and balloon and overtube-assisted enteroscopy to define the presence and activity of Crohn's enteritis and additional chapters defining the use of random biopsies versus chromoendoscopy, and computer enhanced imaging to define possible dysplasia development. The book also includes access to online videos, making it the ultimate verbal and visual tool for all medical professionals interested in the advances in the field over the last several decades.Endoscopy in Inflammatory Bowel Disease is a concise text that is of great value to practicing endoscopists, gastroenterologists, general or colorectal surgeons, physicians in training, and all medical professionals caring for patients with inflammatory bowel disease.

Lewin's Gastrointestinal Pathology and Its Clinical Implications, Second Edition This comprehensive, two-volume resource highlights the practical aspects the pathology of biopsies and gross specimens, the clinical/pathological correlation, and differential diagnoses, and the ways in which these affect the management of patients with gastrointestinal disorders. The authors provide valuable insights on many important areas of gastrointestinal pathology, and openly address controversies within the specialty. This all-inclusive work stands alone in its illustrative quality and in its emphasis on the clinical implications of patient management as related to pathologic findings. The Second Edition has been completely revised to reflect two decades of advances in the field. The book's focus on clinical/pathological correlations and differential diagnoses emphasizes their affect on patient management. Major revisions of the chapters on colitis and gastritis feature new approaches to treatment. Over 2100 full-color illustrations highlight pathologic features to sharpen diagnostic skills and guide treatment choices. NEW to the Second Edition… Completely revised content reflects two decades of advances in the field. Focus on clinical/pathological correlations and differential diagnoses emphasizes their affect on patient management Major revisions of the chapters on colitis and gastritis feature new approaches to treatment. Over 2100 full-color illustrations highlight pathologic features to sharpen diagnostic skills and guide treatment choices.

Nonpolypoid Colorectal Neoplasms in Inflammatory Bowel Disease, An Issue of Gastrointestinal Endoscopy Clinics,

Der hier vorliegende Band 2 der zweiten Auflage der Pathologie, der der ersten Hälfte des zweiten Bandes der ersten Auflage entspricht, enthält alle Kapitel zu den Verdauungsorganen. Er bietet eine vollständige Aktualisierung der Stoffdarstellung. Die Darstellung ist klinik- und praxisbezogen. Die klare Gliederung innerhalb eines jeden Kapitels, die graphische Hervorhebung der didaktisch wesentlichen Inhalte sowie zahlreiche Abbildungen erleichtern die rasche Orientierung.

In diesem Buch werden Klinik, Diagnostik, Therapie und Grundlagen des Morbus Crohn und der Colitis ulcerosa praxisbezogen und umfassend dargestellt. Die zunehmende Bedeutung des Ultraschalls, der Endosonographie und der Kernspintomographie in der Diagnostik sowie die Erweiterung des therapeutischen Spektrums durch 5-Aminosalizylsäure, Cyclosporin und Budesonid sind ausführlich beschrieben. Einen besonderen Schwerpunkt bildet die Darstellung der klinischen Bilder, der extraintestinalen Manifestationen und der zahlreichen Differentialdiagnosen. Ziel des Buches ist es, zu einem besseren Verständnis der klinischen Symptomatik, zu einer zeitgerechten Diagnosestellung und zu einem begründeten Therapiekonzept beizutragen.

Dr. Kahi has assembled top experts to provide clinically focused articles on colonoscopy and polypectomy. The issue is divided into sections devote to Technique Fundamentals, Advances in Technique, Technology, Neoplasia Detection, Quality and Outcomes, and The Future. Everyone from early-career gastroenteorlogists to those late in their career should find this edition to be very valuable.

Pediatric Inflammatory Bowel Disease, Second Edition provides an essential reference with an emphasis on the unique pediatric issues of IBD. Chapters focus on complications of IBD specific to children and adolescents. Treatment recommendations are based on the latest clinical research available. The textbook also presents sections dedicated to the aspects of participation in clinical research unique to children and adolescents and the complicated yet vital process of successfully transitioning a patient from a pediatric to adult specialist. Controversies in pediatric IBD care such as the off-label use of medications are also covered. The format incorporates multiple tables, graphs, and figures to improve readability and make for an efficient reference for clinicians to use.Thoroughly revised and updated from the first edition, the volumes includes new therapies that are currently being used or tested for treatment of IBD, important areas regarding incidence and prevalence, immunization and response to vaccine administration as well as advancements in our understanding of growth and development with particular to the use of growth hormone therapy. Other new areas covered include important topics of complementary and alternative medicine use in IBD, immunization, and liver disease in IBD. Pediatric Inflammatory Bowel Disease, Second Edition is a valuable resource for pediatric gastroenterologists as well as adult gastroenterologists.

Eine signifikante Verbesserung der Heilungs- und Überlebensraten war in den letzten Jahren bei metastasierten gastrointestinalen Tumoren nicht zu beobachten. Umso wichtiger ist es, die vorhandenen therapeutischen Möglichkeiten sorgfältig zu evaluieren und die interdisziplinäre Zusammenarbeit weiter zu optimieren. Als ein für den Patienten höchst relevantes Ergebnis dieser Kooperation sind die jüngsten Ergebnisse der großen Studien zur adjuvanten Chemotherapie beim Kolonkarzinom und zur adjuvanten Chemo-/Strahlentherapie beim Rektumkarzinom zu werten, die kürzlich einen signifikanten Überlebensvorteil durch diese adjuvante Therapie nachgewiesen haben. In diesem Band werden für Oesophagus-, Magen-, Kolon-, Rektum-, Pankreas-, Gallen- und Analkarzinome die Ergebnisse der neuesten Studie präsentiert und für jeden Tumor die Wertigkeit von Chemotherapie, Chirurgie, Strahlentherapie und Immunmodulation bezüglich Prognose dargestellt.

Morson and Dawson's Gastrointestinal Pathology 5th Edition Edited by Neil A. Shepherd, DM, FRCPath, Gloucestershire Cellular Pathology Laboratory, Cheltenham, UK; Bryan F. Warren, MB, ChB, FRCP (London), FRCPath, John Radcliffe Hospital, Oxford, UK; Geraint T. Williams, OBE, BSc, MD, MRCR, FRCP (London), FRCPath, FMedSci, Cardiff University, Cardiff, UK; Joel K. Greenson, MD, University of Michigan Medical School, Ann Arbor, MI, USA; Gregory Y. Lauwers, MD, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; and Marco R. Novelli, MB, ChB, PhD, FRCPath, University College Hospital, London, UK Emphasizing the important role the gastrointestinal pathologist now plays in patient management, Morson and Dawson's Gastrointestinal Pathology, 5th Edition, is a comprehensive resource for both training and practice. This revision of a “gold standard” textbook reflects current practice, where the abundance of surgical specimens and the revolution in endoscopy has made virtually the entire gastrointestinal tract accessible to biopsy. Generations of practitioners valued Morson and Dawson's candid guidance, highly readable text, and abundant, high-quality illustrations. This edition preserves those popular features and, to add an international dimension, now includes authors from North America, the European continent, Asia, and Australia. Authors write on their areas of expertise, with chapters organized into seven major parts: Oesophagus Stomach Small Intestine Appendix Large Intestine The Anal Region Peritoneum Each part opens with a chapter on normal anatomy, dissection, and relevant histology. The following chapters describe the morphology, pathogenesis, and aetiology of specific disorders and incorporate developments in molecular pathology and immunohistochemistry. A concluding chapter in each part summarizes miscellaneous conditions of that organ. More than 700 colour images throughout the text illustrate the discussion. An associated website contains all the figures for easy downloading into presentations. With outstanding contributions from the world's leading gastrointestinal pathologists and a wealth of new information, Morson and Dawson's Gastrointestinal Pathology, 5th Edition, will serve a new generation of gastrointestinal pathologists, gastroenterologists, and pathologists as the definitive reference for the field.

Comprehensive and complete, Shackelford's Surgery of the Alimentary Tract delivers the definitive, clinically oriented, cutting-edge guidance you need to achieve optimal outcomes managing the entire spectrum of gastrointestinal disorders. Make effective use of the latest endoscopic, robotic, and minimally invasive procedures as well as medical therapies with unbeatable advice from a'who's who'of international authorities!Find expert answers to any clinical question in gastrointestinal surgery, from the esophagus to the colon.See exactly what to look for and how to proceed from an abundance of beautifully detailed intraoperative and laparoscopic photographs.

Der'Pouch', ein aus Darmschlingen neu gebildetes Reservoir, hat sich in Chirurgie und Urologie als rekonstruktives Prinzip durchgesetzt. In dem vorliegenden Werk wird dem Leser durch nationale und internationale Experten ein aktueller Wissensstand zu sämtlichen Aspekten der Pouch-Chirurgie vermittelt. Sowohl für den Gastroenterologen bzw. Urologen als auch für den auf diesem Gebiet operativ tätigen Chirurgen werden systematisch die Bedeutung des Organverlustes, die operative Technik der verschiedenen Rekonstruktionen und die Komplikationsbeherrschung beschrieben. Ein weiterer Schwerpunkt liegt in der Evaluierung der postoperativen Funktion, hieraus resultierender klinisch relevanter Folgezustände und die jeweilige Lebensqualität.

This issue presents a concise clinical overview on the most current knowledge on advanced imaging modalities. Dr. Ananadasabapathy has secured internationally recognized authors to write articles on endomicoscopy, molecular imagaing, optical coherence tomography, and chromoendoscopy. Articles are also devoted to imaging the biliary tree and red flag technologies in gastric neoplasia.

Atlas of Dermatological Manifestations of Gastrointestinal Disease provides a comprehensive compendium of digestive tract diseases with dermatological manifestations. The work is arranged by digestive symptoms, with sections based on the specific digestive disease etiology. Each section contains paired chapters of text, one on gastrointestinal manifestations and the other on dermatological manifestations. The atlas includes clinical presentations, pathophysiology, differential diagnosis, diagnostic tests/procedures, pathology, and references presented with substantial numbers of images. Concise and easy to use, Atlas of Dermatological Manifestations of Gastrointestinal Disease is an important resource for gastroenterologists, dermatologists, and internists alike in the treatment of digestive tract diseases.