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After an initial slow diffusion of minimal invasive approaches in liver surgery, laparoscopy has now been implemented worldwide. This process has been sped up after several papers showed the superiority of laparoscopy over the open approach with regard to short-term outcomes. Before, the adaptation and diffusion of LLS was much slower compared to other general surgical specialties. The challenge in controlling major hemorrhage, the risk of gas embolism, the steepness of the learning curve and the uncertainty about oncological outcomes were barriers for the implementation of LLS. Nowadays, laparoscopic liver resections (LLR) are considered safe and feasible. The same evolution is seen in the diffusion of robotic liver surgery (RLS). The first reported robotic liver resection was published in 2003. Introduction of RLS has remained very slow compared to other subspecialties. This could be attributed to the complexity of minimally invasive liver surgery and the steep learning curve to overcome. Furthermore, the absence of instruments for parenchyma transection appeared to be a barrier for many surgeons to start RLS. Nowadays, Robotic liver surgery is in it's pioneering phase and limited to a few high volume centers. Furthermore data regarding the implementation of RLS are still scarce and the reproducibility of the implementation is still debated. This textbook will offer readers a useful overview of RLS state of the art, collecting the contributions of renowned robotic liver surgeons from Europe, Asia and the Americas. The editors will collaborate with a professional medical illustrator specialized in minimal invasive liver surgery to offer readers a visual experience of the most important surgical steps.

Psychosomatik spielt in der Gastroenterologie und Hepatologie eine immer noch zu wenig beachtete Rolle. Ausgehend vom Begriff des Bauchhirns (Brain-Gut-Axis) werden die psychosomatischen Aspekte sämtlicher Erkrankungen des Magen-Darm-Traktes ausführlich besprochen. In dieser aktualisierten und erweiterten Neuauflage kommen Expertinnen und Experten zu Wort, die die Psychosomatik als wichtigen Bestandteil Ihrer Patientenbetreuung integrieren. Die Bedeutung der Arzt-Patient-Beziehung wird praxisnah in diesem Buch vermittelt und durch Berichte von Betroffenen ergänzt. In weiterer Folge werden psychische Aspekte bei der endoskopischen Untersuchung und anderen diagnostischen Verfahren vorgestellt. Die psychopharmakologische Therapie psychischer Störungen im gastroenterologischen Alltag wird Raum gegeben und Modelle einer integrierten psychosomatischen Versorgung beispielhaft dargestellt. Im Sinne der evidenzbasierten Medizin bietet es den in Ausbildung stehenden Medizinern einen umfassenden Überblick über die aktuellen Entwicklungen der psychosomatischen Forschung des Verdauungstraktes.

​Das Buch vermittelt in knapper und verständlicher Form die Grundlagen und Besonderheiten der Ernährungsmedizin, wobei dieses breit angelegte Fach nahezu alle klinischen Disziplinen betrifft. Das besondere Kennzeichen des Buches ist sein handlungs- und lösungsorientierter Ansatz. Als Orientierungshilfe ist es nicht nur wissensvermittelnd, sondern kann für viele Fragestellungen als praktisches Nachschlagewerk für den beruflichen Alltag dienen. Die Inhalte orientieren sich an dem aktualisierten (Muster)-Kursbuch der BÄK für die Zusatz-Weiterbildung „Ernährungsmedizin“. Es werden physiologische und biochemische Grundlagen von Ernährung, Verdauung und Stoffwechsel sowie ernährungsmedizinische Probleme bei verschiedenen Krankheitsbildern einschließlich von enteraler und parenteraler Ernährung beschrieben. Die Strategien von Prävention und Therapie werden gleichwertig dargestellt, sodass auch Public Health Themen nicht zu kurz kommen.Das Buch eignet sich hervorragend zur Prüfungsvorbereitung, ist aber auch aufgrund der vielen praktischen Hinweise ein wertvoller Begleiter für alle ernährungsmedizinisch tätigen Ärzte..

Although the incidence of Helicobacter infection has been declining for the past decades, it is still one of the most common infectious disease all over the world. Over 50,000 research articles have been published so far and lots of studies are on-going. Most of previously published books dealt with so many issues and it is somewhat hard for the reader to apply in real world clinical practice. Since clinicians do not have enough time to read the book from head to the end, this book presents algorithms, tables, and figures at the end of each chapter to provide a brief summary for clinicians, so that they can use this book as a reference in a short time in clinical practice. Readers will find up-to-date information and guidance on diagnosis and different types of treatments.

Körperliche Erkrankungen gehen in ihrem Verlauf mit einer hohen psychischen Komorbidität einher. Vor allem eine koexistente Depression und Angst, ein chronischer oder traumatischer Stress üben einen relevanten negativen Einfluss auf das dynamische Krankheitsgeschehen aus. Sie sind nicht nur häufig mit einer erhöhten Morbidität, einer ungünstigeren Lebensqualität und belasteten psychosozialen Integration assoziiert. Sie sind oft auch mit einem erhöhten Mortalitätsrisiko und einem bedenkenswerten Suizidrisiko verbunden. Depression, Angst, chronischer und posttraumatischer Stress können auch die Entwicklung von körperlichen Krankheiten beeinflussen, indem sie allgemeine somatische Krankheitsrisiken vermitteln. Sowohl eine psycho-somatische als auch ein somato-psychische Perspektive ist notwendig, um die komplexen Interaktionen zwischen psychologischer, psychosozialer und biologischer Ebene zu erfassen. Ein allgemeiner Teil nimmt das Thema von psychischer und somatischer Komorbidität in einer bidirektionalen Wirkrichtung auf. Er befasst sich mit theoretischen Konzepten und empirischen Befunden zu möglichen Beziehungen zwischen somatischer Krankheit und medizinischer Behandlungsmodalität einerseits und psychischer Vulnerabilität und Störung andererseits, die traditionellerweise einer „psychosomatischen Perspektive“ in der Medizin zugeordnet werden. In einem speziellen Teil werden diese allgemeinen Aspekte einer biopsychosozialen Betrachtung von Depression, Angst und traumatischem Stress in ihrem potentiellen Einfluss auf definierte internistische Krankheitsrisiken bzw. von koexistenter depressiver, Angst- und posttraumatischer Belastungsstörung bei internistischen Erkrankungen in ihren möglichen Auswirkungen auf Krankheitsdynamik und Krankheitsverlauf jeweils nach traditionellen Organsystemen bzw. nach speziellen medizinischen Behandlungskontexten je gesondert dargestellt. Dieses umfangreiche Werk richtet sich gleichermaßen an die Kolleg•innenaus Psychiatrie und Psychotherapie wie aus den medizinischen Fächern, sowie an alle Leser•innen, die an einer psychosomatischen und somatopsychischen Perspektive auf die komplexen wechselseitigen Beziehungen zwischen psychischen Störungen und körperlichen Krankheiten interessiert sind.

The book offers a comprehensive and didactic overview of both advanced diagnostic and therapeutic endoscopy imaging techniques, with a clinical impact correspondent in major gastroenterology, hepatology, and pancreatology diseases.It includes state-of-the art techniques like endoscopic ultrasound and confocal laser endomicroscopy, as well as endoscopic retrograde cholangio-pancreatography. Divided into 9 main chapters, the book covers the examination techniques, the sedation and monitoring, and investigates the clinical impact of endoscopy. Specific chapters are dedicated to the upper gastrointestinal tract, the lower gastrointestinal tract, to pancreatico-biliary diseases and to liver diseases. Enriched by more than 400 original images based on 25 years'experience in the field of advanced endoscopy imaging, and accompanied by carefully selected videos, this volume will be a reference guide for residents and trainees in gastroenterology, hepatology, pancreatology,and surgery, with emphasis on endoscopy techniques.

In diesem Praxisbuch haben Experten auf diesem Gebiet das aktuelle Wissen zur Differenzialdiagnostik und zur Therapie - konservativ bis operativ - zusammengefasst.Das klinische Bild der Refluxkrankheit ist sehr vielfältig. Neben den klassischen Symptomen Sodbrennen und Schmerz hinter dem Brustbein können auch atypische Beschwerden wie Asthma, chronischerer Husten und Heiserkeit als Folge der Refluxerkrankung auftreten. Im schlimmsten Fall kann sich auch als Folge eines langjährigen Refluxes Speiseröhrenkrebs bilden. Insbesondere bei atypischen Symptomen ist aber die Diagnostik erschwert. Hier muss die klinische Expertise durch differenzierten Einsatz von apparativer Diagnostik ergänzt werden. Dieses Praxisbuch leistet eine Hilfestellung in der Funktionsdiagnostik und erläutert mögliche Diagnoseverfahren. Im Therapieteil werden konservative wie auch operative Optionen mit notwendigen Indikationen aufgezeigt. Kapitel zu den Besonderheiten bei Kindern mit Refluxund einem Auftreten bestimmter Symptome während der Schwangerschaft runden das Buch ab. Die Inhalte orientieren sich an der aktualisierten Leitlinie „Gastroösophageale Refluxkrankheit“.Neben der hohen Prävalenz und der deutlichen Einschränkung der Lebensqualität liegt die Bedeutung der Erkrankung im breiten klinischen Spektrum an Symptomen, Komplikationen und Folgeerkrankungen mit Relevanz für zahlreiche Fachdisziplinen auch außerhalb der Gastroenterologie. So bietet dieses Buch einen kompakten Wissenstranfer zum Krankheitsbild - nicht nur für Gastroenterologen.

Bile duct injuries (BDI) are considered the most serious surgical complication associated with cholecystectomy. According to different reports, its incidence has remained constant over the years, ranging from 0.1% to 0.9%. BDI is associated with a greater risk of perioperative morbidity and mortality, a reduction in the quality of life, and a decrease in long-term survival. Also, this complication is a concern to surgeons since its progression is uncertain and may lead to demands on professional responsibility ('malpractice') and emotional and physical consequences ('second victim').Given that injuries in a high percentage of patients are initially unsuspected, the postoperative recovery may be prolonged, and the possibility of a successful repair reduced. Several surgical, endoscopic, and percutaneous procedures may be necessary to manage the lesions and to treat coexisting complications. BDI patients often undergo several repair attempts before successful resolution. This affects their quality of life and has a high psychological, physical, and mental impact due to the prolonged, complex, and unexpected nature of the injury. This currently represents a frequent problem in specialized referral centers or hepatobilopancreatic surgery units, where patients arrive with the sequelae of previous inadequate treatments. Usually, these patients require more elaborate procedures such as reoperations, liver resections and liver transplantation. The prevention, early diagnosis, and adequate treatment in the first approach is of crucial importance to ensure good long-term results. Therefore, this book is an essential resource for surgeons who perform cholecystectomy or treat BDI patients. It provides practical information and a comprehensive review on prevention and proper management, including complex cases. Readers will find contributions by experienced authors from a multidisciplinary and reference team in the management of BDI patients.

This book presents a comprehensive collection of classic cases and problem scenarios encountered as bedside case discussions during ward rounds. It facilitates the practical management of hepatic disorders. The unique aspect of hepatology involves the blend of the basic tenet of clinical medicine applied to liver disease and a multitude of interventional modalities in the management of liver, biliary, and pancreatic diseases. This book takes the reader through the process of ruling in and ruling out possibilities based on clinical data (history and examination) and then traces the logical trajectory of each case from recommended investigations to the analysis of test results and finally to making a syndromic diagnosis. By adopting an evidence-based approach, the book emphasizes analytical and need-based studies to exclude any mimics. This book helps practice hepatologists and gastroenterologists for a systematic approach towards the most common cases.

Mit diesem Buch für die Kitteltasche oder als eBook auf dem Smartphone behalten Sie die Nerven vor und während Ihres ersten Dienstes auf einer gastroenterologischen Station. Dieser Guide beantwortet alle wichtigen Fragen, die Sie sich vor Ihrem ersten Einsatz stellen: Wann sollte eine Endoskopie durchgeführt werden? Wann muss ich den Oberarzt rufen? Auf welche Notfälle muss ich vorbereitet sein? Von wichtigen Laborwerten über organisatorische Aspekte und Notfallsituationen, bis hin zum Umgang mit Fieber und Dysphagie finden Sie zahlreiche Tipps und Tricks für das ideale Vorgehen. Von jungen Gastroenterologen geschrieben, die wissen, was junge Ärzte für eine gute Vorbereitung ihrer ersten Dienste brauchen. Plus: eBook inklusive.Für jeden Weiterbildungsassistenten, der seine ersten Dienste in der Gastroenterologie souverän meistern möchte!

Die nicht-alkoholische Fettlebererkrankung gilt als'neue Seuche der Hepatologie', als diejenige Lebererkrankung mit den höchsten Zuwachsraten weltweit. Prognosen sagen eine Zunahme des Phänomens um 50% und eine darauf basierende Verdreifachung der Zirrhoseraten bis 2030 voraus.Dieses Buch dient zum Nachschlagen zu allen Fragen um das vielfältige Krankheitsbild der nicht-alkoholischen Fettleber (NAFLD). Es bildet den aktuellen Stand der Wissenschaft ab mit seinen diagnostischen Verfahren und Therapieoptionen sowie neuen Entwicklungen auf diesem Gebiet.Tabellen, Übersichten und Algorithmen, erlauben ein schnelles Erfassen der wichtigsten Punkte und eine strukturierte Diagnostik und Therapie. Grundlagen zur Pathogenese und Physiologie führen in das Thema ein. Weiterhin werden die Differentialdiagnostik und unterschiedliche Therapieverfahren erläutert. Dabei wird die gesamte therapeutische Bandbreite von der Verhaltensänderung über die Ernährung bis hin zu den neusten Medikamenten dargestellt. Auf spezifische Patientengruppen wie z.B. Kinder oder adipöse Patienten wird gesondert eingegangen. Weiterhin werden auch Komorbiditäten wie z.B. Hepatozelluläres Karzinom bei NAFLD oder NAFLD bei chronischen Lebererkrankungen und der Einfluss von Genussmitteln detailliert besprochen. Für alle Gastroenterologen und Hepatologen sowie für interessierte Internisten und Weiterbildungsassistenten ein praktisches Nachschlagewerk.

This book offers a comprehensive overview of the latest standard medical procedures and surgical techniques for biliary atresia (BA), as well as the perioperative care, long-term follow-up and transitions. Experts on pediatrics in such fields as hepatology, surgery, pathology, and liver transplantation present their research findings and analyses of this rare and intractable disease of unknown etiology. In Japan, shared experience and sound understanding based on conferences and guidelines have led to standardization of management and clinical care and, as a result, better outcomes. Providing insights into improving surgical outcomes, and including special chapters focusing on social support systems for patients and families as well as recent advances in early diagnosis, this book a valuable resource for medical professionals around the globe who are involved in treating biliary atresia. It is especially useful for pediatric hepatologists, pediatric surgeons and transplant surgeons.

This book highlights the work of pioneers in this field, in order to inspire their peers, healthcare leaders and an interested audience. Prior to the respective care practices, the authors describe the core of personalized care and illustrate its connections to value-driven care and evidence-based medicine. The last part of the book addresses organizational and other conditions under which personalized care can thrive.In the Netherlands, substantial work is being done on value-driven care and more is currently being discussed. This book focuses on the benefits of value-driven care for patients and healthcare providers alike. To do so, it explores a range of representative cases and scenarios, such as: Scenario 1: You are able to surgically remove the most difficult tumors and find out one day that you don't need to do so in all indicated patients. Later you can find out how to recognize when surgery isn't the best treatment for certain patients. And now your team hasa fixed routine to find the optimal choice together with the patient. Scenario 2: You consider yourself to be a patient-centered doctor who is really in touch with their patients – until you ask them to report for themselves on how they are doing. In the'patient-reported outcomes'you see that you have completely missed an important aspect. Later, you can structurally integrate this into your outpatient clinic. Scenario 3: In line with the planning principles of your hospital, you see chronic patients once a year – and of course also'as needed'– until your data shows you that you see patients too early or too late, but rarely when it would be most helpful. Later you can discover how to offer your consultation exactly on time – based on early signals and often even before the patient calls the clinic. This is what value-driven care is all about: care is of more significance to the patient when it is tailored to his or her unique situation. Recognizingthe patient's needs, preferences and values, and structurally adapting care accordingly – that is the noble profession of value-driven care, which takes us an important step closer to the ideal of personalized care.

This book provides an in-depth coverage not only of liver pathology but also of diagnosis of the numerous types of liver disease, placing specific emphasis on current treatments of liver pathology including the most up-to-date information on liver transplantation. The first part of provides an in-depth account of the liver pathology in different conditions such as Hepatits, liver ischaemia reperfusion injury, Lyme disease, cirrhotic cardiomyopathy and hepatocellular carcinoma. The second part provides a comprehensive overview of diagnostic methods. Of particular interest are chapters on the latest techniques in Patient-specific 3D printing and transient elastography (FibroScan). The final part focuses on treatment and provides a step-by step guide to the therapeutic management of liver diseases starting with pharmacological treatment and techniques including surgery and liver transplantation. This is an invaluable book for clinicians, practitioners including academics, scientists/researchers and postgraduates to provide the newest knowledge in the field of liver pathogenesis. It is written by a multidisciplinary team of experts in hepathology, gastroenterology, and surgery especially from liver transplantation.

This book offers a comprehensive overview of liver failure including Epidemiology, mechanism of the disease, and its clinical manifestations. The diagnosis of numerous types of liver disease leading to liver failure; with specific emphasis on the current and future treatment modalities including up-to-date and extensive information on liver transplantation. It provides the most up-to-date information on liver failure for clinicians, practitioners including GPs, scientists/researchers, postgraduates and allied health professionals. It features an overview of the relevant classification and epidemiologic aspects of acute liver failure along with a thorough review of the mechanisms associated with acute liver failure and multisystemic involvement. Detailed guidance is also provided on the latest treatment techniques including those available for liver transplantation and potential future approaches, enabling the reader to develop a detailed understanding of the topic. Liver Failure: Acute and Acute on Chronic provides a practically applicable guide to the epidemiology and management of liver failure. It features contributions from an outstanding panel of experts in hepatology, gastroenterology and surgery making it a vital up-to-date reference for trainee and practicing medical professionals in a variety of disciplines who encounter these patients.

This text provides a concise yet comprehensive overview of autoimmune hepatitis (AIH). The book reviews diagnosis criteria for AIH, biochemical and histologic findings in typical and atypical cases, and treatment with first, second, and third line therapies. Furthermore, the book discusses management of AIH for specific patient populations, including pediatric patients, pregnant patients, and patients undergoing liver transplantation. Criteria for stopping therapy and risk of relapse, studies demonstrating the efficacy and safety of alternatives to corticosteroids, and diagnosis and treatment of overlap syndromes are also explored in the text.Written by experts in the field, Diagnosis and Treatment of Autoimmune Hepatitis: A Clinical Guide is a state-of-the-art resource for clinicians and practitioners who treat and manage patients with AIH

This text provides a comprehensive and state-of-the-art overview of the evaluation and management of liver mass lesions. Major topics covered include epidemiology, the use of different imaging modalities in the differential diagnosis of liver lesions, the use of biomarkers and immunohistochemical stains for diagnosis, and treatment of the different types of liver masses. These include hepatocellular adenoma and hepatocellular carcinoma, fibrolamellar carcinoma, cholangiocarcinoma, hemangioma, focal nodular hyperplasia, liver masses in adult patients with congenital heart disease, and other infectious, inflammatory, and cystic lesions of the liver. The volume presents highly practical case presentations of typical patients seen in a clinical hepatobiliary practice. Written by experts from multiple disciplines, Evaluation and Management of Liver Masses is a valuable resource for clinicians and professionals who manage patients with these conditions.

This text provides a concise yet comprehensive review of GI tract complications of HIV infection. Beginning with an overview on the pathophysiology of HIV and its direct effect on the GI tract, the book outlines opportunistic infections, noninfectious etiologies, diagnostic testing, and therapy in relation to specific organs in the GI tract. Organs covered include the esophagus, stomach, gallbladder and biliary tract, liver, pancreas, and small and large intestines.Written by experts in the field, HIV and GI Tract Complications: A Comprehensive Clinical Guide is a valuable resource for clinicians and researchers interested in HIV/AIDS and associated GI tract complications, that will help guide patient management and stimulate investigative efforts.

This book describes the latest advances concerning the molecular mechanisms of and therapeutic strategies for alcohol- and non-alcohol-related digestive diseases. Alcohol abuse causes not only liver injury but can harm various organs, resulting in esophageal and colorectal cancers, GERD, pancreatitis, etc. Similar to alcoholic abuse, metabolic syndrome based on obesity and diabetes is also strongly associated with the development of various digestive diseases. Although these diseases may be differentiated by the presence or absence of alcohol intake, the pathologic findings and pathogenesis reveal a number of similarities. This volume covers clinical and basic approaches for esophageal, gastric, hepatic, colorectal and pancreatic diseases associated with alcohol abuse and metabolic syndrome; further, it discusses the roles of microbiota, oxidative stress, and apoptosis, the critical factors causing alcoholic and metabolic digestive diseases. Also, it showcases new pathological and therapeutic perspectives in gastric and pancreatic cancers. Alcoholic/Non-Alcoholic Digestive Diseases will provide invaluable information for doctors specializing in gastroenterology and hepatology and researchers seeking new research on digestive diseases based on alcohol consumption and obesity. ​

This book is the first to provide balanced examination of both pediatric liver disease and liver transplantation – two topics that are inherently related, given that most chronic liver disorders eventually require organ replacement. The different forms of liver disease encountered in the pediatric age group are first discussed in a series of disease-specific chapters that have a reader-friendly, uniform structure covering pathophysiology, diagnostic and treatment algorithms, clinical cases, and transition to adult care. Key topics in the field of liver transplantation are then addressed. Examples include indications and contraindications, surgical techniques and complications, immunosuppression, in pediatric liver transplantation, acute and chronic rejection and allograft dysfunction, and CMV and EBV infection in transplant recipients, long-term graft injury and tolerance. A section on pediatric hepatology across the world includes chapters presenting the features and management of pediatric liver disease in South-America, Africa and Asia. A closing section considers what the future holds for pediatric liver disease and its management, including novel genetic testing, cell therapy and gene therapy. Pediatric Hepatology and Liver Transplantation will be of value for a range of practitioners, from residents making their first approach to pediatric liver disease through to specialists working in transplantation centers.

In the 1990's significant advances in the understanding of viral hepatitis have been observed. In particular, our knowledge of the nature and diversity of viruses causing hepatitis in humans have substantially increased.'Virus Hepatitis” comprehensively and uniquely presents these valuable information all in a single volume for the utmost benefit of medical practitioners, microbiologists, as well as those actively involved in health administration world-wide. The virological, clinical epidemiological, diagnostic, therapeutic, and preventive aspects pertaining to all the types of hepatitis known to date including hepatitis C and E are thoroughly discussed.

This book provides a concise yet comprehensive overview of frailty and sarcopenia in the cirrhotic patient. The text presents a personalized approach to identifying cirrhotic patients at risk of higher morbidity and mortality due to frailty and sarcopenia. It reviews current and novel diagnostic methods, while spotlighting treatment and management strategies for frailty and sarcopenia. The book also focuses on special issues associated with these syndromes, such as the effect of gender, age, and ethnicity on frailty and sarcopenia, sarcopenic obesity, and frailty and sarcopenia after liver transplantation. Future considerations are outlined in the closing chapters, including emerging pharmacological and interventional therapies for these syndromes.Written by experts in the field, Frailty and Sarcopenia in Cirrhosis: The Basics, the Challenges, and the Future is a valuable resource for clinicians and practitioners who treatpatients with cirrhosis.

This book provides a comprehensive overview of the current limitations and unmet needs in Hepatocellular Carcinoma (HCC) diagnosis, treatment, and prevention. It also provides newly emerging concepts, approaches, and technologies to address challenges. Topics covered include changing landscape of HCC etiologies in association with health disparities, framework of clinical management algorithm, new and experimental modalities of HCC diagnosis and prognostication, multidisciplinary treatment options including rapidly evolving molecular targeted therapies and immune therapies, multi-omics molecular characterization, and clinically relevant experimental models. The book is intended to assist collaboration between the diverse disciplines and facilitate forward and reverse translation between basic and clinical research by providing a comprehensive overview of relevant areas, covering epidemiological trend and population-level patient management strategies, new diagnostic and prognostic tools, recent advances in the standard care and novel therapeutic approaches, and new concepts in pathogenesis and experimental approaches and tools, by experts and opinion leaders in their respective fields. By thoroughly and concisely covering whole aspects of HCC care, Hepatocellular Carcinoma serves as a valuable reference for multidisciplinary readers, and promotes the development of personalized precision care strategies that lead to substantial improvement of disease burden and patient prognosis in HCC.

This clinical casebook provides a concise yet comprehensive state-of-the-art review of liver disease. Presented in a case-based format, each case features a scenario centered on a different variant of liver disease, with sections on case history, diagnosis/assessment, treatment, outcomes, alternative approaches, and clinical pearls. Diseases covered include drug-induced liver injury, acute hepatitis, chronic hepatitis, NAFLD, and cholangitis. Scenarios such as liver disease in pregnancy, elevated liver function tests, and liver transplants are also presented in the casebook.Written by experts in the field, Liver Disease: A Clinical Casebook is a valuable resource for clinicians and practitioners who treat patients with liver disease.

This textbook provides a comprehensive and state-of-the-art overview of the major issues specific to the field of pediatric gastroenterology, hepatology, and nutrition. The first part of the book, Gastroenterology and Nutrition, presents in a systematic way the overall scope of issues encountered by children (newborn to teenagers) suffering from disorders of the gastrointestinal tract, pancreas and/or presenting nutritional issues. These chapters are structured in logical sections to facilitate consultation and include major topics ranging from congenital disorders to gastrointestinal problems of the newborn, infectious diseases of the gastrointestinal tract, and approach to nutritional problems in the various pediatric ages. The second part of the book, Hepatology, is articulated in a series of chapters which present a comprehensive review of congenital and acquired disorders of the biliary tract and liver. This section also includes a critical analysis of available diagnostic andtherapeutic procedures and future perspectives.Written by experts in the field, Textbook of Pediatric Gastroenterology, Hepatology and Nutrition: A Comprehensive Guide to Practice constitutes a much needed, innovative resource combining updated, reliable and comprehensive information with agile consultation for a streamlined approach to the care of children with such disorders.